Sjögren's syndrome-like disease in mice with T cells lacking class 1A phosphoinositide-3-kinase

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 45, 2006, Pages 16882-16887

  Oak, Jean S ^a   Deane, Jonathan A ^a,d   Kharas, Michael G ^a   Luo, Ji ^b,c   Lane, Thomas E ^a   Cantley, Lewis C ^b,c   Fruman, David A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

Autoantibodies; Autoimmunity; T lymphocyte

Indexed keywords

ANTINUCLEAR ANTIBODY; CD4 ANTIGEN; CD8 ANTIGEN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOINOSITIDE 3 KINASE 1A; RO ANTIBODY; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY BLOOD LEVEL; ANTIBODY SPECIFICITY; ANTIBODY TITER; ARTICLE; AUTOIMMUNE DISEASE; AUTOIMMUNITY; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL LOSS; CONTROLLED STUDY; CORNEA OPACITY; DRY EYE; EYE IRRITATION; FEMALE; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; LACRIMAL GLAND; LYMPHOCYTIC INFILTRATION; MALE; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SJOEGREN SYNDROME; T LYMPHOCYTE; XEROSTOMIA;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; AUTOANTIBODIES; CELL DIFFERENTIATION; DISEASE MODELS, ANIMAL; HUMANS; LACRIMAL APPARATUS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, MUTANT STRAINS; MICE, TRANSGENIC; SIGNAL TRANSDUCTION; SJOGREN'S SYNDROME; T-LYMPHOCYTES; T-LYMPHOCYTES, HELPER-INDUCER; T-LYMPHOCYTES, REGULATORY;

EID: 33750963809     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0607984103     Document Type: Article

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