Enhanced phosphoinositide 3-kinase δ activity is a frequent event in systemic lupus erythematosus that confers resistance to activation-induced T cell death

Journal of Immunology

Volumn 187, Issue 5, 2011, Pages 2376-2385

  Suárez Fueyo, Abel ^a   Barber, Domingo F ^a   Martínez Ara, Jorge ^b   Zea Mendoza, Antonio C ^c   Carrera, Ana C ^a  

^a CENTRO NACIONAL DE BIOTECNOLOGÍA   (Spain)

^b HOSPITAL UNIVERSITARIO LA PAZ   (Spain)

^c HOSPITAL RAMÓN Y CAJAL   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

AZATHIOPRINE; CYCLOPHOSPHAMIDE; HYDROXYCHLOROQUINE; METHOTREXATE; MYCOPHENOLIC ACID; NONSTEROID ANTIINFLAMMATORY AGENT; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE DELTA; PREDNISONE; TACROLIMUS; UNCLASSIFIED DRUG;

ADULT; ARTICLE; BIOACCUMULATION; CELL DEATH; CELL SURVIVAL; CONTROLLED STUDY; DISEASE ACTIVITY; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IMMUNOLOGICAL TOLERANCE; MAJOR CLINICAL STUDY; MEMORY T LYMPHOCYTE; PERIPHERAL BLOOD MONONUCLEAR CELL; PERIPHERAL LYMPHOCYTE; PRIORITY JOURNAL; SYSTEMIC LUPUS ERYTHEMATOSUS; T LYMPHOCYTE ACTIVATION;

ADULT; APOPTOSIS; BLOTTING, WESTERN; CELL SEPARATION; CELL SURVIVAL; ENZYME ACTIVATION; FEMALE; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; HUMANS; IMMUNOLOGIC MEMORY; LUPUS ERYTHEMATOSUS, SYSTEMIC; LYMPHOCYTE ACTIVATION; MALE; MIDDLE AGED; PHOSPHATIDYLINOSITOL 3-KINASES; PROTEIN-SERINE-THREONINE KINASES; T-LYMPHOCYTES; YOUNG ADULT;

EID: 80052667108     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1101602     Document Type: Article

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