PI3K is a negative regulator of IgE production

International Immunology

Volumn 20, Issue 4, 2008, Pages 499-508

  Doi, Tomomitsu ^a,b,d   Obayashi, Kunie ^a,d   Kadowaki, Takashi ^b,c   Fujii, Hideki ^a,b   Koyasu, Shigeo ^a,b  

^a KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

AID; Class switch recombination; IC87114; Id2; IgE; PI3K; Wortmannin

Indexed keywords

2 (6 AMINO 9 PURINYLMETHYL) 5 METHYL 3 (2 METHYLPHENYL) 3H QUINAZOLIN 4 ONE; ACTIVATION INDUCED CYTIDINE DEAMINASE; CD40 LIGAND MONOCLONAL ANTIBODY; IMMUNOGLOBULIN E; IMMUNOGLOBULIN SUBCLASS; INHIBITOR OF DIFFERENTIATION 2; INTERLEUKIN 4; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN SUBUNIT; WORTMANNIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE ACTIVATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME DEFICIENCY; ENZYME INHIBITION; ENZYME PURIFICATION; HUMORAL IMMUNITY; IMMUNOGLOBULIN PRODUCTION; IN VITRO STUDY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CROSS LINKING; PROTEIN EXPRESSION; REGULATORY MECHANISM; WILD TYPE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; ANTIBODIES; ANTIGEN-ANTIBODY REACTIONS; B-LYMPHOCYTES; CELLS, CULTURED; CYTIDINE DEAMINASE; DOWN-REGULATION; GENE EXPRESSION PROFILING; IMMUNOGLOBULIN CLASS SWITCHING; IMMUNOGLOBULIN E; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PROTEIN KINASE INHIBITORS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 41149103027     PISSN: 09538178     EISSN: 14602377     Source Type: Journal    
DOI: 10.1093/intimm/dxn009     Document Type: Article

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