Biased binding of class IA phosphatidyl inositol 3-kinase subunits to inducible costimulator (CD278)

Cellular and Molecular Life Sciences

Volumn 68, Issue 18, 2011, Pages 3065-3079

  Acosta, Yenny Y ^a   Zafra, Maria Paz ^a   Ojeda, Gloria ^b   Bernardone, Ilaria Seren ^a,c   Dianzani, Umberto ^c   Portolés, Pilar ^b   Rojo, Jose M ^a  

^a CENTRO DE INVESTIGACIONES BIOLÓGICAS   (Spain)

^b INSTITUTO DE SALUD CARLOS III   (Spain)

^c UNIVERSITY OF EASTERN PIEDMONT   (Italy)

Author keywords

ICOS; Inducible costimulator; PI3 Kinase; T lymphocyte

Indexed keywords

CD278 ANTIBODY; CD28 ANTIGEN; CD3 ANTIBODY; CELL ANTIBODY; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE 3 KINASE; PROTEIN KINASE B; PROTEIN P110; PROTEIN P110 ALPHA; PROTEIN P110 BETA; PROTEIN P110 DELTA; PROTEIN P50; PROTEIN P55; PROTEIN P55 ALPHA; PROTEIN P85; PROTEIN P85 ALPHA; PROTEIN P85 BETA; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CATALYSIS; CELL ELONGATION; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME ACTIVATION; ENZYME INHIBITION; MOUSE; NONHUMAN; PRECIPITATION; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION; T LYMPHOCYTE ACTIVATION;

AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; DNA PRIMERS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME-LINKED IMMUNOSORBENT ASSAY; IMMUNOBLOTTING; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED BALB C; MOLECULAR SEQUENCE DATA; PHOSPHATIDYLINOSITOL 3-KINASE; PROTEIN BINDING; PROTEIN SUBUNITS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; T-LYMPHOCYTES;

EID: 80052270140     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-010-0606-1     Document Type: Article

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