Vav1 transduces T cell receptor signals to the activation of phospholipase C-γ1 via phosphoinositide 3-kinase-dependent and -independent pathways

Journal of Experimental Medicine

Volumn 195, Issue 9, 2002, Pages 1103-1114

  Reynolds, Lucinda F ^a   Smyth, Lesley A ^a   Norton, Trisha ^a   Freshney, Norman ^b   Downward, Julian ^b   Kioussis, Dimitris ^a   Tybulewicz, Victor L J ^a  

^a NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^b IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

Itk; Rac1; SLP 76; Tec; Thymus

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOLIPASE C; PHOSPHOPROTEIN; PROTEIN DERIVATIVE; PROTEIN ITK; PROTEIN VAV1; RAC1 PROTEIN; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL POPULATION; CONTROLLED STUDY; ENZYME ACTIVATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; THYMOCYTE; THYMUS;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CALCIUM; CELL CYCLE PROTEINS; ISOENZYMES; MICE; MICE, KNOCKOUT; MODELS, BIOLOGICAL; PHOSPHOLIPASE C; PHOSPHOLIPASE C GAMMA; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-VAV; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; T-LYMPHOCYTES;

EID: 0037029653     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20011663     Document Type: Article

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