-
1
-
-
0942268727
-
Development and selection of marginal zone B cells
-
Lopes-Carvalho, T. and Kearney, J. F., Development and selection of marginal zone B cells. Immunol. Rev. 2004. 197: 192-205.
-
(2004)
Immunol. Rev
, vol.197
, pp. 192-205
-
-
Lopes-Carvalho, T.1
Kearney, J.F.2
-
2
-
-
16844379386
-
Models for peripheral B cell development and homeostasis
-
Srivastava, B., Lindsley, R. C., Nikbakht, N. and Allman, D., Models for peripheral B cell development and homeostasis. Semin. Immunol. 2005. 17: 175-182.
-
(2005)
Semin. Immunol
, vol.17
, pp. 175-182
-
-
Srivastava, B.1
Lindsley, R.C.2
Nikbakht, N.3
Allman, D.4
-
3
-
-
18844398045
-
Marginal zone B cells in lymphocyte activation and regulation
-
Lopes-Carvalho, T., Foote, J. and Kearney, J. F., Marginal zone B cells in lymphocyte activation and regulation. Curr. Opin. Immunol. 2005. 17: 244-250.
-
(2005)
Curr. Opin. Immunol
, vol.17
, pp. 244-250
-
-
Lopes-Carvalho, T.1
Foote, J.2
Kearney, J.F.3
-
4
-
-
0035887778
-
Unique signaling properties of B cell antigen receptor in mature and immature B cells: Implications for tolerance and activation
-
Benschop, R. J., Brandl, E., Chan, A. C. and Cambier, J. C., Unique signaling properties of B cell antigen receptor in mature and immature B cells: Implications for tolerance and activation. J. Immunol. 2001. 167: 4172-4179.
-
(2001)
J. Immunol
, vol.167
, pp. 4172-4179
-
-
Benschop, R.J.1
Brandl, E.2
Chan, A.C.3
Cambier, J.C.4
-
5
-
-
0344069651
-
Distinct signal thresholds for the unique antigen receptor-linked gene expression programs in mature and immature B cells
-
Benschop, R. J., Melamed, D., Nemazee, D. and Cambier, J. C., Distinct signal thresholds for the unique antigen receptor-linked gene expression programs in mature and immature B cells. J. Exp. Med. 1999. 190: 749-756.
-
(1999)
J. Exp. Med
, vol.190
, pp. 749-756
-
-
Benschop, R.J.1
Melamed, D.2
Nemazee, D.3
Cambier, J.C.4
-
6
-
-
0035284811
-
Antigen receptor proximal signaling in splenic B-2 cell subsets
-
Li, X., Martin, F., Oliver, A. M., Kearney, J. F. and Carter, R. H., Antigen receptor proximal signaling in splenic B-2 cell subsets. J. Immunol. 2001. 166: 3122-3129.
-
(2001)
J. Immunol
, vol.166
, pp. 3122-3129
-
-
Li, X.1
Martin, F.2
Oliver, A.M.3
Kearney, J.F.4
Carter, R.H.5
-
7
-
-
33744551665
-
Mouse follicular and marginal zone B cells show differential expression of Dnmt3a and sensitivity to 5′-azacytidine
-
Wang, Y., Zhang, P., Li, W., Hou, L., Wang, J., Liang, Y. and Han, H., Mouse follicular and marginal zone B cells show differential expression of Dnmt3a and sensitivity to 5′-azacytidine. Immunol. Lett. 2006. 105: 174-179.
-
(2006)
Immunol. Lett
, vol.105
, pp. 174-179
-
-
Wang, Y.1
Zhang, P.2
Li, W.3
Hou, L.4
Wang, J.5
Liang, Y.6
Han, H.7
-
8
-
-
33747856465
-
Identification of CD36 as a new surface marker of marginal zone B cells by transcriptomic analysis
-
Zhang, P., Li, W., Wang, Y., Hou, L., Xing, Y., Qin, H., Wang, J. et al., Identification of CD36 as a new surface marker of marginal zone B cells by transcriptomic analysis. Mol. Immunol. 2007. 44: 332-337.
-
(2007)
Mol. Immunol
, vol.44
, pp. 332-337
-
-
Zhang, P.1
Li, W.2
Wang, Y.3
Hou, L.4
Xing, Y.5
Qin, H.6
Wang, J.7
-
9
-
-
1342321748
-
PI3K signaling controls cell fate at many points in B lymphocyte development and activation
-
Donahue, A. C. and Fruman, D. A., PI3K signaling controls cell fate at many points in B lymphocyte development and activation. Semin. Cell Dev. Biol. 2004. 15: 183-197.
-
(2004)
Semin. Cell Dev. Biol
, vol.15
, pp. 183-197
-
-
Donahue, A.C.1
Fruman, D.A.2
-
10
-
-
0038281331
-
Proliferation and survival of activated B cells requires sustained antigen receptor engagement and phosphoinositide 3-kinase activation
-
Donahue, A. C. and Fruman, D. A., Proliferation and survival of activated B cells requires sustained antigen receptor engagement and phosphoinositide 3-kinase activation. J. Immunol. 2003. 170: 5851-5860.
-
(2003)
J. Immunol
, vol.170
, pp. 5851-5860
-
-
Donahue, A.C.1
Fruman, D.A.2
-
11
-
-
0033556333
-
Impaired B cell development and proliferation in absence of phosphoinositide 3-kinase p85alpha
-
Fruman, D. A., Snapper, S. B., Yballe, C. M., Davidson, L., Yu, J. Y., Alt, F. W. and Cantley, L. C., Impaired B cell development and proliferation in absence of phosphoinositide 3-kinase p85alpha. Science 1999. 283: 393-397.
-
(1999)
Science
, vol.283
, pp. 393-397
-
-
Fruman, D.A.1
Snapper, S.B.2
Yballe, C.M.3
Davidson, L.4
Yu, J.Y.5
Alt, F.W.6
Cantley, L.C.7
-
12
-
-
30444439101
-
Key role of the p110delta isoform of PI3K in B-cell antigen and IL-4 receptor signaling: Comparative analysis of genetic and pharmacologic interference with p110delta function in B cells
-
Bilancio, A., Okkenhaug, K., Camps, M., Emery, J. L., Ruckle, T., Rommel, C. and Vanhaesebroeck, B., Key role of the p110delta isoform of PI3K in B-cell antigen and IL-4 receptor signaling: Comparative analysis of genetic and pharmacologic interference with p110delta function in B cells. Blood 2006. 107: 642-650.
-
(2006)
Blood
, vol.107
, pp. 642-650
-
-
Bilancio, A.1
Okkenhaug, K.2
Camps, M.3
Emery, J.L.4
Ruckle, T.5
Rommel, C.6
Vanhaesebroeck, B.7
-
13
-
-
0037119630
-
A crucial role for the p110delta subunit of phosphatidylinositol 3-kinase in B cell development and activation
-
Clayton, E., Bardi, G., Bell, S. E., Chantry, D., Downes, C. P., Gray, A., Humphries, L. A. et al., A crucial role for the p110delta subunit of phosphatidylinositol 3-kinase in B cell development and activation. J. Exp. Med. 2002. 196: 753-763.
-
(2002)
J. Exp. Med
, vol.196
, pp. 753-763
-
-
Clayton, E.1
Bardi, G.2
Bell, S.E.3
Chantry, D.4
Downes, C.P.5
Gray, A.6
Humphries, L.A.7
-
14
-
-
10844255780
-
Altered splenic B cell subset development in mice lacking phosphoinositide 3-kinase p85alpha
-
Donahue, A. C., Hess, K. L., Ng, K. L. and Fruman, D. A., Altered splenic B cell subset development in mice lacking phosphoinositide 3-kinase p85alpha. Int. Immunol. 2004. 16: 1789-1798.
-
(2004)
Int. Immunol
, vol.16
, pp. 1789-1798
-
-
Donahue, A.C.1
Hess, K.L.2
Ng, K.L.3
Fruman, D.A.4
-
15
-
-
9244263536
-
Frontline: The p85alpha isoform of phosphoinositide 3-kinase is essential for a subset of B cell receptor-initiated signaling responses
-
Hess, K. L., Donahue, A. C., Ng, K. L., Moore, T. I., Oak, J. and Fruman, D. A., Frontline: The p85alpha isoform of phosphoinositide 3-kinase is essential for a subset of B cell receptor-initiated signaling responses. Eur. J. Immunol. 2004. 34: 2968-2976.
-
(2004)
Eur. J. Immunol
, vol.34
, pp. 2968-2976
-
-
Hess, K.L.1
Donahue, A.C.2
Ng, K.L.3
Moore, T.I.4
Oak, J.5
Fruman, D.A.6
-
16
-
-
0037695593
-
Essential, nonredundant role for the phosphoinositide 3-kinase p110delta in signaling by the B-cell receptor complex
-
Jou, S. T., Carpino, N., Takahashi, Y., Piekorz, R., Chao, J. R., Carpino, N., Wang, D. and Ihle, J. N., Essential, nonredundant role for the phosphoinositide 3-kinase p110delta in signaling by the B-cell receptor complex. Mol. Cell. Biol. 2002. 22: 8580-8591.
-
(2002)
Mol. Cell. Biol
, vol.22
, pp. 8580-8591
-
-
Jou, S.T.1
Carpino, N.2
Takahashi, Y.3
Piekorz, R.4
Chao, J.R.5
Carpino, N.6
Wang, D.7
Ihle, J.N.8
-
17
-
-
0037047590
-
Impaired B and T cell antigen receptor signaling in p110delta PI 3-kinase mutant mice
-
Okkenhaug, K., Bilancio, A., Farjot, G., Priddle, H., Sancho, S., Peskett, E., Pearce, W. et al., Impaired B and T cell antigen receptor signaling in p110delta PI 3-kinase mutant mice. Science 2002. 297: 1031-1034.
-
(2002)
Science
, vol.297
, pp. 1031-1034
-
-
Okkenhaug, K.1
Bilancio, A.2
Farjot, G.3
Priddle, H.4
Sancho, S.5
Peskett, E.6
Pearce, W.7
-
18
-
-
0037341617
-
PI3K and Btk differentially regulate B cell antigen receptor-mediated signal transduction
-
Suzuki, H., Matsuda, S., Terauchi, Y., Fujiwara, M., Ohteki, T., Asano, T., Behrens, T. W. et al., PI3K and Btk differentially regulate B cell antigen receptor-mediated signal transduction. Nat. Immunol. 2003. 4: 280-286.
-
(2003)
Nat. Immunol
, vol.4
, pp. 280-286
-
-
Suzuki, H.1
Matsuda, S.2
Terauchi, Y.3
Fujiwara, M.4
Ohteki, T.5
Asano, T.6
Behrens, T.W.7
-
19
-
-
0033555829
-
Xid-like immunodeficiency in mice with disruption of the p85alpha subunit of phosphoinositide 3-kinase
-
Suzuki, H., Terauchi, Y., Fujiwara, M., Aizawa, S., Yazaki, Y., Kadowaki, T. and Koyasu, S., Xid-like immunodeficiency in mice with disruption of the p85alpha subunit of phosphoinositide 3-kinase. Science 1999. 283: 390-392.
-
(1999)
Science
, vol.283
, pp. 390-392
-
-
Suzuki, H.1
Terauchi, Y.2
Fujiwara, M.3
Aizawa, S.4
Yazaki, Y.5
Kadowaki, T.6
Koyasu, S.7
-
20
-
-
1342303480
-
Phosphatidylinositol 3-kinase-dependent mitogen-activated protein/extracellular signal-regulated kinase kinase 1/2 and NF-kappa B signaling pathways are required for B cell antigen receptor-mediated cyclin D2 induction in mature B cells
-
Piatelli, M. J., Wardle, C., Blois, J., Doughty, C., Schram, B. R., Rothstein, T. L. and Chiles, T. C., Phosphatidylinositol 3-kinase-dependent mitogen-activated protein/extracellular signal-regulated kinase kinase 1/2 and NF-kappa B signaling pathways are required for B cell antigen receptor-mediated cyclin D2 induction in mature B cells. J. Immunol. 2004. 172: 2753-2762.
-
(2004)
J. Immunol
, vol.172
, pp. 2753-2762
-
-
Piatelli, M.J.1
Wardle, C.2
Blois, J.3
Doughty, C.4
Schram, B.R.5
Rothstein, T.L.6
Chiles, T.C.7
-
21
-
-
0028093139
-
Inhibition of human B lymphocyte cell cycle progression and differentiation by rapamycin
-
Aagaard-Tillery, K. M. and Jelinek, D. F., Inhibition of human B lymphocyte cell cycle progression and differentiation by rapamycin. Cell. Immunol. 1994. 156: 493-507.
-
(1994)
Cell. Immunol
, vol.156
, pp. 493-507
-
-
Aagaard-Tillery, K.M.1
Jelinek, D.F.2
-
22
-
-
0025132636
-
Suppression of B cell activation by cyclosporine A, FK506 and rapamycin
-
Wicker, L. S., Boltz, R. C., Jr., Matt, V., Nichols, E. A., Peterson, L. B. and Sigal, N. H., Suppression of B cell activation by cyclosporine A, FK506 and rapamycin. Eur. J. Immunol. 1990. 20: 2277-2283.
-
(1990)
Eur. J. Immunol
, vol.20
, pp. 2277-2283
-
-
Wicker, L.S.1
Boltz Jr., R.C.2
Matt, V.3
Nichols, E.A.4
Peterson, L.B.5
Sigal, N.H.6
-
23
-
-
1342279422
-
PI3-kinase and TOR: PIKTORing cell growth
-
Richardson, C. J., Schalm, S. S. and Blenis, J., PI3-kinase and TOR: PIKTORing cell growth. Semin. Cell Dev. Biol. 2004. 15: 147-159.
-
(2004)
Semin. Cell Dev. Biol
, vol.15
, pp. 147-159
-
-
Richardson, C.J.1
Schalm, S.S.2
Blenis, J.3
-
24
-
-
32044465506
-
TOR signaling in growth and metabolism
-
Wullschleger, S., Loewith, R. and Hall, M. N., TOR signaling in growth and metabolism. Cell 2006. 124: 471-484.
-
(2006)
Cell
, vol.124
, pp. 471-484
-
-
Wullschleger, S.1
Loewith, R.2
Hall, M.N.3
-
25
-
-
0032518467
-
3-Phosphoinositide-dependent protein kinase 1 (PDK1) phosphorylates and activates the p70 S6 kinase in vivo and in vitro
-
Alessi, D. R., Kozlowski, M. T., Weng, Q. P., Morrice, N. and Avruch, J., 3-Phosphoinositide-dependent protein kinase 1 (PDK1) phosphorylates and activates the p70 S6 kinase in vivo and in vitro. Curr. Biol. 1998. 8: 69-81.
-
(1998)
Curr. Biol
, vol.8
, pp. 69-81
-
-
Alessi, D.R.1
Kozlowski, M.T.2
Weng, Q.P.3
Morrice, N.4
Avruch, J.5
-
26
-
-
0036342294
-
Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway
-
Manning, B. D., Tee, A. R., Logsdon, M. N., Blenis, J. and Cantley, L. C., Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway. Mol. Cell 2002. 10: 151-162.
-
(2002)
Mol. Cell
, vol.10
, pp. 151-162
-
-
Manning, B.D.1
Tee, A.R.2
Logsdon, M.N.3
Blenis, J.4
Cantley, L.C.5
-
27
-
-
24744435392
-
Activation of mammalian target of rapamycin in transformed B lymphocytes is nutrient dependent but independent of Akt, mitogen-activated protein kinase/extracellular signal-regulated kinase kinase, insulin growth factor-I, and serum
-
Wlodarski, P., Kasprzycka, M., Liu, X., Marzec, M., Robertson, E. S., Slupianek, A. and Wasik, M. A., Activation of mammalian target of rapamycin in transformed B lymphocytes is nutrient dependent but independent of Akt, mitogen-activated protein kinase/extracellular signal-regulated kinase kinase, insulin growth factor-I, and serum. Cancer Res. 2005. 65: 7800-7808.
-
(2005)
Cancer Res
, vol.65
, pp. 7800-7808
-
-
Wlodarski, P.1
Kasprzycka, M.2
Liu, X.3
Marzec, M.4
Robertson, E.S.5
Slupianek, A.6
Wasik, M.A.7
-
28
-
-
8744275597
-
The p110delta subunit of phosphoinositide 3-kinase is required for the lipopolysaccharide response of mouse B cells
-
Hebeis, B. J., Vigorito, E. and Turner, M., The p110delta subunit of phosphoinositide 3-kinase is required for the lipopolysaccharide response of mouse B cells. Biochem. Soc. Trans. 2004. 32: 789-791.
-
(2004)
Biochem. Soc. Trans
, vol.32
, pp. 789-791
-
-
Hebeis, B.J.1
Vigorito, E.2
Turner, M.3
-
29
-
-
14844351587
-
Coligation of the B cell receptor with complement receptor type 2 (CR2/ CD21) using its natural ligand C3dg: Activation without engagement of an inhibitory signaling pathway
-
Lyubchenko, T., dal Porto, J., Cambier, J. C. and Holers, V. M., Coligation of the B cell receptor with complement receptor type 2 (CR2/ CD21) using its natural ligand C3dg: Activation without engagement of an inhibitory signaling pathway. J. Immunol. 2005. 174: 3264-3272.
-
(2005)
J. Immunol
, vol.174
, pp. 3264-3272
-
-
Lyubchenko, T.1
dal Porto, J.2
Cambier, J.C.3
Holers, V.M.4
-
30
-
-
0035892228
-
Resolution of three nonproliferative immature splenic B cell subsets reveals multiple selection points during peripheral B cell maturation
-
Allman, D., Lindsley, R. C., Demuth, W., Rudd, K., Shinton, S. A. and Hardy, R. R., Resolution of three nonproliferative immature splenic B cell subsets reveals multiple selection points during peripheral B cell maturation. J. Immunol. 2001. 167: 6834-6840.
-
(2001)
J. Immunol
, vol.167
, pp. 6834-6840
-
-
Allman, D.1
Lindsley, R.C.2
Demuth, W.3
Rudd, K.4
Shinton, S.A.5
Hardy, R.R.6
-
31
-
-
0033526816
-
B cell development in the spleen takes place in discrete steps and is determined by the quality of B cell receptor-derived signals
-
Loder, F., Mutschler, B., Ray, R. J., Paige, C. J., Sideras, P., Torres, R., Lamers, M. C. and Carsetti, R., B cell development in the spleen takes place in discrete steps and is determined by the quality of B cell receptor-derived signals. J. Exp. Med. 1999. 190: 75-89.
-
(1999)
J. Exp. Med
, vol.190
, pp. 75-89
-
-
Loder, F.1
Mutschler, B.2
Ray, R.J.3
Paige, C.J.4
Sideras, P.5
Torres, R.6
Lamers, M.C.7
Carsetti, R.8
-
32
-
-
27744491859
-
-
Srivastava, B., Quinn, W. J., 3rd, Hazard, K., Erikson, J. and Allman, D., Characterization of marginal zone B cell precursors. J. Exp. Med. 2005. 202: 1225-1234.
-
Srivastava, B., Quinn, W. J., 3rd, Hazard, K., Erikson, J. and Allman, D., Characterization of marginal zone B cell precursors. J. Exp. Med. 2005. 202: 1225-1234.
-
-
-
-
33
-
-
0036498795
-
Transitional B lymphocyte subsets operate as distinct checkpoints in murine splenic B cell development
-
Su, T. T. and Rawlings, D. J., Transitional B lymphocyte subsets operate as distinct checkpoints in murine splenic B cell development. J. Immunol. 2002. 168: 2101-2110.
-
(2002)
J. Immunol
, vol.168
, pp. 2101-2110
-
-
Su, T.T.1
Rawlings, D.J.2
-
34
-
-
0032545343
-
The inositol phosphatase SHIP inhibits Akt/PKB activation in B cells
-
Aman, M. J., Lamkin, T. D., Okada, H., Kurosaki, T. and Ravichandran, K. S., The inositol phosphatase SHIP inhibits Akt/PKB activation in B cells. J. Biol. Chem. 1998. 273: 33922-33928.
-
(1998)
J. Biol. Chem
, vol.273
, pp. 33922-33928
-
-
Aman, M.J.1
Lamkin, T.D.2
Okada, H.3
Kurosaki, T.4
Ravichandran, K.S.5
-
35
-
-
0037189571
-
Convergence of signaling pathways on the activation of ERK in B cells
-
Jacob, A., Cooney, D., Pradhan, M. and Coggeshall, K. M., Convergence of signaling pathways on the activation of ERK in B cells. J. Biol. Chem. 2002. 277: 23420-23426.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 23420-23426
-
-
Jacob, A.1
Cooney, D.2
Pradhan, M.3
Coggeshall, K.M.4
-
36
-
-
23444446774
-
Coordinate analysis of murine immune cell surface markers and intracellular phosphoproteins by flow cytometry
-
Krutzik, P. O., Clutter, M. R. and Nolan, G. P., Coordinate analysis of murine immune cell surface markers and intracellular phosphoproteins by flow cytometry. J. Immunol. 2005. 175: 2357-2365.
-
(2005)
J. Immunol
, vol.175
, pp. 2357-2365
-
-
Krutzik, P.O.1
Clutter, M.R.2
Nolan, G.P.3
-
37
-
-
23444432362
-
Characterization of the murine immunological signaling network with phosphospecific flow cytometry
-
Krutzik, P. O., Hale, M. B. and Nolan, G. P., Characterization of the murine immunological signaling network with phosphospecific flow cytometry. J. Immunol. 2005. 175: 2366-2373.
-
(2005)
J. Immunol
, vol.175
, pp. 2366-2373
-
-
Krutzik, P.O.1
Hale, M.B.2
Nolan, G.P.3
-
38
-
-
0036173143
-
Simultaneous measurement of multiple active kinase states using polychromatic flow cytometry
-
Perez, O. D. and Nolan, G. P., Simultaneous measurement of multiple active kinase states using polychromatic flow cytometry. Nat. Biotechnol. 2002. 20: 155-162.
-
(2002)
Nat. Biotechnol
, vol.20
, pp. 155-162
-
-
Perez, O.D.1
Nolan, G.P.2
-
39
-
-
33645318725
-
Phospho-proteomic immune analysis by flow cytometry: From mechanism to translational medicine at the single-cell level
-
Perez, O. D. and Nolan, G. P., Phospho-proteomic immune analysis by flow cytometry: From mechanism to translational medicine at the single-cell level. Immunol. Rev. 2006. 210: 208-228.
-
(2006)
Immunol. Rev
, vol.210
, pp. 208-228
-
-
Perez, O.D.1
Nolan, G.P.2
-
40
-
-
33746214828
-
Kinetics of B cell receptor signaling in human B cell subsets mapped by phosphospecific flow cytometry
-
Irish, J. M., Czerwinski, D. K., Nolan, G. P. and Levy, R., Kinetics of B cell receptor signaling in human B cell subsets mapped by phosphospecific flow cytometry. J. Immunol. 2006. 177: 1581-1589.
-
(2006)
J. Immunol
, vol.177
, pp. 1581-1589
-
-
Irish, J.M.1
Czerwinski, D.K.2
Nolan, G.P.3
Levy, R.4
-
41
-
-
35348812273
-
Measuring phosphorylated Akt and other phosphoinositide-3-kinase-regulated phosphoproteins in primary lymphocytes
-
Donahue, A. C. and Fruman, D. A., Measuring phosphorylated Akt and other phosphoinositide-3-kinase-regulated phosphoproteins in primary lymphocytes. Methods Enzymol. 2007. 434: 131-154.
-
(2007)
Methods Enzymol
, vol.434
, pp. 131-154
-
-
Donahue, A.C.1
Fruman, D.A.2
-
42
-
-
0037342166
-
Pten inactivation alters peripheral B lymphocyte fate and reconstitutes CD19 function
-
Anzelon, A. N., Wu, H. and Rickert, R. C., Pten inactivation alters peripheral B lymphocyte fate and reconstitutes CD19 function. Nat. Immunol. 2003. 4: 287-294.
-
(2003)
Nat. Immunol
, vol.4
, pp. 287-294
-
-
Anzelon, A.N.1
Wu, H.2
Rickert, R.C.3
-
43
-
-
0036171199
-
Activation of the PKB/AKT pathway by ICAM-2
-
Perez, O. D., Kinoshita, S., Hitoshi, Y., Payan, D. G., Kitamura, T., Nolan, G. P. and Lorens, J. B., Activation of the PKB/AKT pathway by ICAM-2. Immunity 2002. 16: 51-65.
-
(2002)
Immunity
, vol.16
, pp. 51-65
-
-
Perez, O.D.1
Kinoshita, S.2
Hitoshi, Y.3
Payan, D.G.4
Kitamura, T.5
Nolan, G.P.6
Lorens, J.B.7
-
44
-
-
0442309363
-
Role of phospholipase D1 in the regulation of mTOR activity by lysophosphatidic acid
-
Kam, Y. and Exton, J. H., Role of phospholipase D1 in the regulation of mTOR activity by lysophosphatidic acid. FASEB J. 2004. 18: 311-319.
-
(2004)
FASEB J
, vol.18
, pp. 311-319
-
-
Kam, Y.1
Exton, J.H.2
-
45
-
-
33646548305
-
The amino acid sensitive TOR pathway from yeast to mammals
-
Dann, S. G. and Thomas, G., The amino acid sensitive TOR pathway from yeast to mammals. FEBS Lett. 2006. 580: 2821-2829.
-
(2006)
FEBS Lett
, vol.580
, pp. 2821-2829
-
-
Dann, S.G.1
Thomas, G.2
-
46
-
-
0034986036
-
Antigen-receptor cross-linking and lipopolysaccharide trigger distinct phosphoinositide 3-kinase-dependent pathways to NF-kappa B activation in primary B cells
-
Bone, H. and Williams, N. A., Antigen-receptor cross-linking and lipopolysaccharide trigger distinct phosphoinositide 3-kinase-dependent pathways to NF-kappa B activation in primary B cells. Int. Immunol. 2001. 13: 807-816.
-
(2001)
Int. Immunol
, vol.13
, pp. 807-816
-
-
Bone, H.1
Williams, N.A.2
-
47
-
-
18644376284
-
IRF3 mediates a TLR3/TLR4-specific antiviral gene program
-
Doyle, S., Vaidya, S., O'Connell, R., Dadgostar, H., Dempsey, P., Wu, T., Rao, G. et al., IRF3 mediates a TLR3/TLR4-specific antiviral gene program. Immunity 2002. 17: 251-263.
-
(2002)
Immunity
, vol.17
, pp. 251-263
-
-
Doyle, S.1
Vaidya, S.2
O'Connell, R.3
Dadgostar, H.4
Dempsey, P.5
Wu, T.6
Rao, G.7
-
48
-
-
8444224619
-
Balancing Akt with S6K: Implications for both metabolic diseases and tumorigenesis
-
Manning, B. D., Balancing Akt with S6K: Implications for both metabolic diseases and tumorigenesis. J. Cell Biol. 2004. 167: 399-403.
-
(2004)
J. Cell Biol
, vol.167
, pp. 399-403
-
-
Manning, B.D.1
-
49
-
-
33847217892
-
A novel mechanism for Bcr-Abl action: Bcr-Abl-mediated induction of the eIF4F translation initiation complex and mRNA translation
-
Prabhu, S., Saadat, D., Zhang, M., Halbur, L., Fruehauf, J. P. and Ong, S. T., A novel mechanism for Bcr-Abl action: Bcr-Abl-mediated induction of the eIF4F translation initiation complex and mRNA translation. Oncogene 2007. 26: 1188-1200.
-
(2007)
Oncogene
, vol.26
, pp. 1188-1200
-
-
Prabhu, S.1
Saadat, D.2
Zhang, M.3
Halbur, L.4
Fruehauf, J.P.5
Ong, S.T.6
-
50
-
-
0033563309
-
high lymphocytes enriched in the splenic marginal zone generate effector cells more rapidly than the bulk of follicular B cells
-
high lymphocytes enriched in the splenic marginal zone generate effector cells more rapidly than the bulk of follicular B cells. J. Immunol. 1999. 162: 7198-7207.
-
(1999)
J. Immunol
, vol.162
, pp. 7198-7207
-
-
Oliver, A.M.1
Martin, F.2
Kearney, J.F.3
-
51
-
-
22144455025
-
Vav proteins are required for B-lymphocyte responses to LPS
-
Hebeis, B., Vigorito, E., Kovesdi, D. and Turner, M., Vav proteins are required for B-lymphocyte responses to LPS. Blood 2005. 106: 635-640.
-
(2005)
Blood
, vol.106
, pp. 635-640
-
-
Hebeis, B.1
Vigorito, E.2
Kovesdi, D.3
Turner, M.4
-
52
-
-
0030832150
-
Marginal zone B cells exhibit unique activation, proliferative and immunoglobulin secretory responses
-
Oliver, A. M., Martin, F., Gartland, G. L., Carter, R. H. and Kearney, J. F., Marginal zone B cells exhibit unique activation, proliferative and immunoglobulin secretory responses. Eur. J. Immunol. 1997. 27: 2366-2374.
-
(1997)
Eur. J. Immunol
, vol.27
, pp. 2366-2374
-
-
Oliver, A.M.1
Martin, F.2
Gartland, G.L.3
Carter, R.H.4
Kearney, J.F.5
-
53
-
-
33749685322
-
Regulation of class-switch recombination and plasma cell differentiation by phosphatidylinositol 3-kinase signaling
-
Omori, S. A., Cato, M. H., Anzelon-Mills, A., Puri, K. D., Shapiro-Shelef, M., Calame, K. and Rickert, R. C., Regulation of class-switch recombination and plasma cell differentiation by phosphatidylinositol 3-kinase signaling. Immunity 2006. 25: 545-557.
-
(2006)
Immunity
, vol.25
, pp. 545-557
-
-
Omori, S.A.1
Cato, M.H.2
Anzelon-Mills, A.3
Puri, K.D.4
Shapiro-Shelef, M.5
Calame, K.6
Rickert, R.C.7
-
54
-
-
0029882545
-
Phosphatidylinositol 3-kinase activation in normal human B lymphocytes
-
Aagaard-Tillery, K. M. and Jelinek, D. F., Phosphatidylinositol 3-kinase activation in normal human B lymphocytes. J. Immunol. 1996. 156: 4543-4554.
-
(1996)
J. Immunol
, vol.156
, pp. 4543-4554
-
-
Aagaard-Tillery, K.M.1
Jelinek, D.F.2
-
55
-
-
0019865787
-
Marginal zones: The major B cell compartment of rat spleens
-
Kumararatne, D. S., Bazin, H. and MacLennan, I. C., Marginal zones: The major B cell compartment of rat spleens. Eur. J. Immunol. 1981. 11: 858-864.
-
(1981)
Eur. J. Immunol
, vol.11
, pp. 858-864
-
-
Kumararatne, D.S.1
Bazin, H.2
MacLennan, I.C.3
-
56
-
-
25444457577
-
hVps34 is a nutrient-regulated lipid kinase required for activation of p70 S6 kinase
-
Byfield, M. P., Murray, J. T. and Backer, J. M., hVps34 is a nutrient-regulated lipid kinase required for activation of p70 S6 kinase. J. Biol. Chem. 2005. 280: 33076-33082.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 33076-33082
-
-
Byfield, M.P.1
Murray, J.T.2
Backer, J.M.3
-
57
-
-
26444575415
-
Amino acids mediate mTOR/ raptor signaling through activation of class 3 phosphatidylinositol 3OH-kinase
-
Nobukuni, T., Joaquin, M., Roccio, M., Dann, S. G., Kim, S. Y., Gulati, P., Byfield, M. P. et al., Amino acids mediate mTOR/ raptor signaling through activation of class 3 phosphatidylinositol 3OH-kinase. Proc. Natl. Acad. Sci. USA 2005. 102: 14238-14243.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 14238-14243
-
-
Nobukuni, T.1
Joaquin, M.2
Roccio, M.3
Dann, S.G.4
Kim, S.Y.5
Gulati, P.6
Byfield, M.P.7
-
58
-
-
15444378732
-
Modulation of the mammalian target of rapamycin pathway by diacylglycerol kinase-produced phosphatidic acid
-
Avila-Flores, A., Santos, T., Rincon, E. and Merida, I., Modulation of the mammalian target of rapamycin pathway by diacylglycerol kinase-produced phosphatidic acid. J. Biol. Chem. 2005. 280: 10091-10099.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 10091-10099
-
-
Avila-Flores, A.1
Santos, T.2
Rincon, E.3
Merida, I.4
-
59
-
-
0036776168
-
A novel pathway regulating the mammalian target of rapamycin (mTOR) signaling
-
Chen, J. and Fang, Y., A novel pathway regulating the mammalian target of rapamycin (mTOR) signaling. Biochem. Pharmacol. 2002. 64: 1071-1077.
-
(2002)
Biochem. Pharmacol
, vol.64
, pp. 1071-1077
-
-
Chen, J.1
Fang, Y.2
-
60
-
-
0035976615
-
Phosphatidic acid-mediated mitogenic activation of mTOR signaling
-
Fang, Y., Vilella-Bach, M., Bachmann, R., Flanigan, A. and Chen, J., Phosphatidic acid-mediated mitogenic activation of mTOR signaling. Science 2001. 294: 1942-1945.
-
(2001)
Science
, vol.294
, pp. 1942-1945
-
-
Fang, Y.1
Vilella-Bach, M.2
Bachmann, R.3
Flanigan, A.4
Chen, J.5
-
61
-
-
33750813851
-
Identification of a novel human lysophosphatidic acid acyltransferase, LPAAT-theta, which activates mTOR pathway
-
Tang, W., Yuan, J., Chen, X., Gu, X., Luo, K., Li, J., Wan, B. et al., Identification of a novel human lysophosphatidic acid acyltransferase, LPAAT-theta, which activates mTOR pathway. J. Biochem. Mol. Biol. 2006. 39: 626-635.
-
(2006)
J. Biochem. Mol. Biol
, vol.39
, pp. 626-635
-
-
Tang, W.1
Yuan, J.2
Chen, X.3
Gu, X.4
Luo, K.5
Li, J.6
Wan, B.7
-
62
-
-
0028302987
-
Protection from endotoxic shock in mice by pharmacologic inhibition of phosphatidic acid
-
Rice, G. C., Brown, P. A., Nelson, R. J., Bianco, J. A., Singer, J. W. and Bursten, S., Protection from endotoxic shock in mice by pharmacologic inhibition of phosphatidic acid. Proc. Natl. Acad. Sci. USA 1994. 91: 3857-3861.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 3857-3861
-
-
Rice, G.C.1
Brown, P.A.2
Nelson, R.J.3
Bianco, J.A.4
Singer, J.W.5
Bursten, S.6
-
63
-
-
33144458615
-
Signaling roles of diacylglycerol kinases
-
Topham, M. K., Signaling roles of diacylglycerol kinases. J. Cell. Biochem. 2006. 97: 474-484.
-
(2006)
J. Cell. Biochem
, vol.97
, pp. 474-484
-
-
Topham, M.K.1
-
64
-
-
0037629646
-
-
Fukao, T. and Koyasu, S., PI3K and negative regulation of TLR signaling. Trends Immunol. 2003. 24: 358-363.
-
Fukao, T. and Koyasu, S., PI3K and negative regulation of TLR signaling. Trends Immunol. 2003. 24: 358-363.
-
-
-
-
65
-
-
33646471083
-
TLR5-mediated phosphoinositide 3-kinase activation negatively regulates flagellin-induced proinflammatory gene expression
-
Yu, Y., Nagai, S., Wu, H., Neish, A. S., Koyasu, S. and Gewirtz, A. T., TLR5-mediated phosphoinositide 3-kinase activation negatively regulates flagellin-induced proinflammatory gene expression. J. Immunol. 2006. 176: 6194-6201.
-
(2006)
J. Immunol
, vol.176
, pp. 6194-6201
-
-
Yu, Y.1
Nagai, S.2
Wu, H.3
Neish, A.S.4
Koyasu, S.5
Gewirtz, A.T.6
-
66
-
-
0033520020
-
Bacterial lipopolysaccharide induced B cell activation is mediated via a phosphatidylinositol 3-kinase dependent signaling pathway
-
Venkataraman, C., Shankar, G., Sen, G. and Bondada, S., Bacterial lipopolysaccharide induced B cell activation is mediated via a phosphatidylinositol 3-kinase dependent signaling pathway. Immunol. Lett. 1999. 69: 233-238.
-
(1999)
Immunol. Lett
, vol.69
, pp. 233-238
-
-
Venkataraman, C.1
Shankar, G.2
Sen, G.3
Bondada, S.4
-
67
-
-
0029831167
-
Direct inhibition of the signaling functions of the mammalian target of rapamycin by the phosphoinositide 3-kinase inhibitors, wortmannin and LY294002
-
Brunn, G. J., Williams, J., Sabers, C., Wiederrecht, G., Lawrence, J. C., Jr. and Abraham, R. T., Direct inhibition of the signaling functions of the mammalian target of rapamycin by the phosphoinositide 3-kinase inhibitors, wortmannin and LY294002. EMBO J. 1996. 15: 5256-5267.
-
(1996)
EMBO J
, vol.15
, pp. 5256-5267
-
-
Brunn, G.J.1
Williams, J.2
Sabers, C.3
Wiederrecht, G.4
Lawrence Jr., J.C.5
Abraham, R.T.6
-
68
-
-
33646383684
-
A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signaling
-
Knight, Z. A., Gonzalez, B., Feldman, M. E., Zunder, E. R., Goldenberg, D. D., Williams, O., Loewith, R. et al., A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signaling. Cell 2006. 125: 733-747.
-
(2006)
Cell
, vol.125
, pp. 733-747
-
-
Knight, Z.A.1
Gonzalez, B.2
Feldman, M.E.3
Zunder, E.R.4
Goldenberg, D.D.5
Williams, O.6
Loewith, R.7
-
69
-
-
0033712984
-
Xid-like phenotypes: A B cell signalosome takes shape
-
Fruman, D. A., Satterthwaite, A. B. and Witte, O. N., Xid-like phenotypes: A B cell signalosome takes shape. Immunity 2000. 13: 1-3.
-
(2000)
Immunity
, vol.13
, pp. 1-3
-
-
Fruman, D.A.1
Satterthwaite, A.B.2
Witte, O.N.3
|