Critical roles of Pten in B cell homeostasis and immunoglobulin class switch recombination

Journal of Experimental Medicine

Volumn 197, Issue 5, 2003, Pages 657-667

  Suzuki, Akira ^a,b,g   Kaisho, Tsuneyasu ^a,c   Ohishi, Minako ^a   Tsukio Yamaguchi, Manae ^a   Tsubata, Takeshi ^d   Koni, Pandelakis A ^f   Sasaki, Takehiko ^e,g   Mak, Tak Wah ^g,h   Nakano, Toru ^a  

^a OSAKA UNIVERSITY   (Japan)

^b AKITA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c RIKEN YOKOHAMA INSTITUTE   (Japan)

^d TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^e TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

^f MEDICAL COLLEGE OF GEORGIA   (United States)

^g UNIVERSITY OF TORONTO   (Canada)

^h Advanced Medical Discovery Institute   (Canada)

Author keywords

Activation induced cytidine deaminase; Class switch recombination; Marginal zone B cells; Mutation; PTEN

Indexed keywords

AUTOANTIBODY; CYTIDINE DEAMINASE; IMMUNOGLOBULIN CLASS;

ANIMAL CELL; ANTIBODY BLOOD LEVEL; APOPTOSIS; ARTICLE; B LYMPHOCYTE; CELL MATURATION; CONTROLLED STUDY; ENZYME INDUCTION; GENE MUTATION; GENE REARRANGEMENT; HOMEOSTASIS; LYMPHOCYTE MIGRATION; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; OVARY FOLLICLE CELL; PRIORITY JOURNAL; PTEN GENE; SPLEEN; TUMOR SUPPRESSOR GENE;

ANIMALS; APOPTOSIS; AUTOANTIBODIES; B-LYMPHOCYTE SUBSETS; B-LYMPHOCYTES; GERMINAL CENTER; HOMEOSTASIS; HUMANS; IMMUNOGLOBULIN CLASS SWITCHING; IMMUNOGLOBULINS; INTEGRASES; LYMPHOCYTE ACTIVATION; MICE; MUTATION; PHOSPHORIC MONOESTER HYDROLASES; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; TIME FACTORS; TUMOR SUPPRESSOR PROTEINS; VIRAL PROTEINS;

EID: 0037416216     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20021101     Document Type: Article

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