Should Alzheimer's disease be equated with human brain ageing?: A maladaptive interaction between brain evolution and senescence

Ageing Research Reviews

Volumn 11, Issue 1, 2012, Pages 104-122

  Neill, David ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

Ageing; Default network; Neuroplasticity; Posteromedial cortex; Senescence

Indexed keywords

AMYLOID; APOLIPOPROTEIN E; CLATHRIN ASSEMBLY PROTEIN; SYNAPTOBREVIN 2; TAU PROTEIN;

ALZHEIMER DISEASE; AMYLOIDOSIS; BRAIN ATROPHY; BRAIN DEVELOPMENT; BRAIN DYSFUNCTION; BRAIN METABOLISM; DEMENTIA; DNA MODIFICATION; DOWN REGULATION; ENDOCYTOSIS; ENTORHINAL CORTEX; EPISODIC MEMORY; EVOLUTIONARY ADAPTATION; GLYCOLYSIS; GRAY MATTER; HIPPOCAMPUS; HUMAN; INCIDENCE; INFERIOR PARIETAL LOBULE; MALADJUSTMENT; METABOLIC DISORDER; NERVE CELL LESION; NERVE CELL NETWORK; NERVE CELL PLASTICITY; NONHUMAN; OXIDATIVE STRESS; PARAHIPPOCAMPAL GYRUS; POSTERIOR CINGULATE; PRECUNEUS; PREFRONTAL CORTEX; PROTEIN PHOSPHORYLATION; REGULATORY DNA SEQUENCE; RETROSPLENIAL CORTEX; REVIEW; SENESCENCE; TEMPORAL CORTEX; VISUAL CORTEX;

AGED; AGED, 80 AND OVER; AGING; ALZHEIMER DISEASE; BRAIN; HUMANS; NERVE DEGENERATION;

EID: 83855164141     PISSN: 15681637     EISSN: 18729649     Source Type: Journal    
DOI: 10.1016/j.arr.2011.06.004     Document Type: Review

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