Testing the rate-of-living/oxidative damage theory of aging in the nematode model Caenorhabditis elegans

Experimental Gerontology

Volumn 42, Issue 9, 2007, Pages 845-851

  Brys, Kristel ^a   Vanfleteren, Jacques R ^a   Braeckman, Bart P ^a  

^a GHENT UNIVERSITY   (Belgium)

Author keywords

Caenorhabditis elegans; daf 2(e1370); Oxidative damage hypothesis; Rate of living hypothesis

Indexed keywords

REACTIVE OXYGEN METABOLITE; SOMATOMEDIN C;

ADOLESCENT; AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; CAENORHABDITIS ELEGANS; CARBONYLATION; CONTROLLED STUDY; ENERGY METABOLISM; LIFESPAN; NONHUMAN; OXIDATION; PREDICTION; PRIORITY JOURNAL; SHORT SURVEY; STRESS;

AGING; ANIMALS; ANTIOXIDANTS; BASAL METABOLISM; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; LONGEVITY; MODELS, ANIMAL; MUTATION; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; RECEPTOR, INSULIN;

CAENORHABDITIS ELEGANS;

EID: 34547956260     PISSN: 05315565     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exger.2007.02.004     Document Type: Short Survey

References (36)

1. Braeckman B.P., Houthoofd K., and Vanfleteren J.R. Assessing metabolic activity in aging Caenorhabditis elegans: concepts and controversies. Aging Cell 1 (2002) 82-88
2. Braeckman B.P., Houthoofd K., and Vanfleteren J.R. Energy metabolism, anti-oxidant defense and aging in Caenorhabditis elegans. In: Nyström T., and Osiewacz H.D. (Eds). Topics in Current Genetics. Model Systems in Aging vol. 3 (2003), Springer-Verlag, Berlin, Heidelberg 99-144
3. Brand M.D., Affourtit C., Esteves T.C., Green K., Lambert A.J., Miwa S., Pakay J.L., and Parker N. Mitochondrial superoxide: production, biological effects, and activation of uncoupling proteins. Free Radic. Biol. Med. 37 (2004) 755-767
4. Clancy D.J., Gems D., Harshman L.G., Oldham S., Stocker H., Hafen E., Leevers S.J., and Partridge L. Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein. Science 292 (2001) 104-106
5. Cypser J.R., and Johnson T.E. Multiple stressors in Caenorhabditis elegans induce stress hormesis and extended longevity. J. Gerontol. Biol. Sci. 57A (2002) B109-B114
6. Duhon S.A., and Johnson T.E. Movement as an index of vitality: comparing wild type and the age-1 mutant of Caenorhabditis elegans. J. Gerontol. Biol. Sci. 50A (1995) B254-B261
7. Feng J., Bussiere F., and Hekimi S. Mitochondrial electron transport is a key determinant of life span in Caenorhabditis elegans. Dev. Cell 1 (2001) 633-644
8. Friedman D.B., and Johnson T.E. A mutation in the age-1 gene in Caenorhabditis elegans lengthens life and reduces hermaphrodite fertility. Genetics 118 (1988) 75-86
9. Garigan D., Hsu A.L., Fraser A.G., Kamath R.S., Ahringer J., and Kenyon C. Genetic analysis of tissue aging in Caenorhabditis elegans. A role for heat-shock factor and bacterial proliferation. Genetics 161 (2002) 1101-1112
10. Gems D., Sutton A.J., Sundermeyer M.L., Albert P.S., King K.V., Edgley M.L., Larsen P.L., and Riddle D.L. Two pleiotropic classes of daf-2 mutation affect larval arrest, adult behavior, reproduction and longevity in Caenorhabditis elegans. Genetics 150 (1998) 129-155
11. Halaschek-Wiener J., Khattra J.S., Mckay S., Pouzyrev A., Stott J.M., Yang G.S., Holt R.A., Jones S.J.M., Marra M.A., Brooks-Wilson A.R., and Riddle D.L. Analysis of long-lived C. elegans daf-2 mutants using serial analysis of gene expression. Genome Res. 15 (2005) 603-615
12. Hansen M., Taubert S., Crawford D., Libina N., Lee S.-L., and Kenyon C. Lifespan extension by conditions that inhibit translation in Caenorhabditis elegans. Aging Cell 6 (2007) 95-110
13. Harman D. Aging: a theory based on free radical and radiation chemistry. J. Gerontol. 11 (1956) 298-300
14. Herndon L.A., Schmeissner P.J., Dudaronek J.M., Brown P.A., Listner K.M., Sakano Y., Paupard M.C., Hall D.H., and Driscoll M. Stochastic and genetic factors influence tissue-specific decline in ageing C. elegans. Nature 419 (2002) 808-814
15. Holzenberger M., Dupont J., Ducos B., Leneuve P., Geloen A., Even P.C., Cervera P., and Le Bouc Y. IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice. Nature 421 (2003) 182-187
16. Houthoofd K., Braeckman B.P., and Vanfleteren J.R. Metabolism and life span determination in C. elegans. In: Mattson M.P. (Ed). Advances in Cell Aging and Gerontology. Energy Metabolism and Lifespan Determination vol. 14 (2003), Elsevier, Amsterdam 143-175
17. Hulbert A.J., Clancy D.J., Mair W., Braeckman B.P., Gems D., and Partridge L. Metabolic rate is not reduced by dietary-restriction or by lowered insulin/IGF-1 signalling and is not correlated with individual lifespan in Drosophila melanogaster. Exp. Gerontol. 39 (2004) 1137-1143
18. Iser W.B., Kim D., Bachman E., and Wolkow C. Examination of the requirement for ucp-4, a putative homolog of mammalian uncoupling proteins, for stress tolerance and longevity in C. elegans. Mech. Ageing Dev. 126 (2005) 1090-1096
19. Ishii N., Goto S., and Hartman P. Protein oxidation during aging of the nematode Caenorhabditis elegans. Free Radic. Biol. Med. 33 (2002) 1021-1025
20. Johnson T.E. Increased life-span of age-1 mutants in Caenorhabditis elegans and lower Gompertz rate of aging. Science 249 (1990) 908-912
21. Johnson T.E., Wu D., Tedesco P., Dames S., and Vaupel J.W. Age-specific demographic profiles of longevity mutants in Caenorhabditis elegans show segmental effects. J. Gerontol. Biol. Sci. 56A (2001) B331-B339
22. Kenyon C., Chang J., Gensch E., Rudner A., and Tabtiang R. A C. elegans mutant that lives twice as long as wild type. Nature 366 (1993) 461-464
23. Khazaeli A.A., Van Voorhies W., and Curtsinger J.W. Longevity and metabolism in Drosophila melanogaster: genetic correlations between life span and age-specific metabolic rate in populations artificially selected for long life. Genetics 169 (2005) 231-242
24. Kimura K.D., Tissenbaum H.A., Liu Y., and Ruvkun G. daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans. Science 277 (1997) 942-946
25. Loeb J., and Northrop J.H. On the influence of food and temperature upon the duration of life. J. Biol. Chem. 32 (1917) 102-121
26. McElwee J.J., Schuster E., Blanc E., Thornton J., and Gems D. Diapause-associated metabolic traits reiterated in long-lived daf-2 mutants in the nematode Caenorhabditis elegans. Mech. Ageing Dev. 127 (2006) 458-472
27. Melendez A., Tallóczy Z., Seaman M., Eskelinen E.-L., Hall D., and Levine B. Autophagy genes are essential for dauer development and life-span extension in C. elegans. Science 301 (2003) 1387-1391
28. Miwa S., Riyahi K., Partridge L., and Brand M.D. Lack of correlation between mitochondrial reactive oxygen species production and life span in Drosophila. Ann. N Y Acad. Sci. 1019 (2004) 388-391
29. Murphy C.T., McCarroll S.A., Bargmann C.I., Fraser A., Kamath R.S., Ahringer J., Li H., and Kenyon C. Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans. Nature 424 (2003) 277-284
30. Pearl R. The Rate of Living (1928), University of London Press, London
31. Rubner M. Das problem des lebensdauer und zeine beziehungen zum wachstum und ernährung (1908), Oldenbourg, Munich
32. Scott B.A., Avidan M.S., and Crowder C.M. Regulation of hypoxic death in C. elegans by the insulin/IGF receptor homolog DAF-2. Science 296 (2002) 2388-2391
33. Speakman J.R., Talbot D.A., Selman C., Snart S., Mclaren J.S., Redman P., Krol E., Jackson D.M., Johnson M.S., and Brand M.D. Uncoupled and surviving: individual mice with high metabolism have greater mitochondrial uncoupling and live longer. Aging Cell 3 (2004) 87-95
34. Van Voorhies W.A., Khazaeli A.A., and Curtsinger J.W. Lack of correlation between body mass and metabolic rate in Drosophila melanogaster. J. Insect Physiol. 50 (2004) 445-453
35. Yasuda K., Adachi H., Fujiwara Y., and Ishii N. Protein carbonyl accumulation in aging dauer formation-defective (daf) mutants of Caenorhabditis elegans. J. Gerontol. Biol. Sci. 54A (1999) B47-B51 discussion B52-B53
36. Yasuda K., Ishii T., Suda H., Akatsuka A., Hartman P.S., Goto S., Miyazawa M., and Ishii N. Age-related changes of mitochondrial structure and function in C. elegans. Mech. Ageing Dev. 127 (2006) 763-770