Altered deactivation in individuals with genetic risk for Alzheimer's disease

Neuropsychologia

Volumn 46, Issue 6, 2008, Pages 1679-1687

  Persson, J ^a   Lind, J ^b   Larsson, A ^c   Ingvar, M ^b   Sleegers, K ^d,e   Van Broeckhoven, C ^d,e   Adolfsson, R ^c   Nilsson, L G ^a   Nyberg, L ^c  

^a STOCKHOLM UNIVERSITY   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c UMEÅ UNIVERSITY   (Sweden)

^d DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^e UNIVERSITY OF ANTWERP   (Belgium)

Author keywords

AD; Aging; Alzheimer's disease; APOE; Compensation; Deactivation; fMRI; Genetic; Memory encoding

Indexed keywords

ADULT; AGED; ALLELE; ALZHEIMER DISEASE; APOLIPOPROTEIN E4 GENE; ARTICLE; BRAIN FUNCTION; CONTROLLED STUDY; CORRELATION ANALYSIS; EPISODIC MEMORY; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; GENE; GENETIC ANALYSIS; GENETIC RISK; HETEROZYGOTE; HUMAN; HYPOTHESIS; MALE; NERVE CELL NECROSIS; SEMANTIC DIFFERENTIAL METHOD;

AGED; ALZHEIMER DISEASE; APOLIPOPROTEIN E4; BRAIN; BRAIN MAPPING; FEMALE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MALE; MEMORY; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; OXYGEN; SEMANTICS;

EID: 43849097422     PISSN: 00283932     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropsychologia.2008.01.026     Document Type: Article

References (41)

1. Aupee A.M., Desgranges B., Eustache F., Lalevee C., de la Sayette V., Viader F., et al. Voxel-based mapping of brain hypometabolism in permanent amnesia with PET. Neuroimage 13 (2001) 1164-1173
2. Bassett S.S., Yousem D.M., Cristinzio C., Kusevic I., Yassa M.A., Caffo B.S., et al. Familial risk for Alzheimer's disease alters fMRI activation patterns. Brain 129 (2006) 1229-1239
3. Binder J.R., Frost J.A., Hammeke T.A., Bellgowan P.S., Rao S.M., and Cox R.W. Conceptual processing during the conscious resting state. A functional MRI study. Journal of Cognitive Neuroscience 11 (1999) 80-95
4. Bookheimer S.Y., Strojwas M.H., Cohen M.S., Saunders A.M., Pericak-Vance M.A., Mazziotta J.C., et al. Patterns of brain activation in people at risk for Alzheimer's disease. New England Journal of Medicine 343 (2000) 450-456
5. Braak H., and Braak E. Pathology of Alzheimer's disease. In: Calne D.B. (Ed). Neurodegenerative diseases (1994), Saunders, Philadelphia 585-613
6. Cabeza R., Anderson N.D., Locantore J.K., and McIntosh A.R. Aging gracefully: Compensatory brain activity in high-performing older adults. Neuroimage 17 (2002) 1394-1402
7. Celone K.A., Calhoun V.D., Dickerson B.C., Atri A., Chua E.F., Miller S.L., et al. Alterations in memory networks in mild cognitive impairment and Alzheimer's disease: An independent component analysis. Journal of Neuroscience 26 (2006) 10222-10231
8. Della-Maggiore V., Sekuler A.B., Grady C.L., Bennett P.J., Sekuler R., and McIntosh A.R. Corticolimbic interactions associated with performance on a short-term memory task are modified by age. Journal of Neuroscience 20 (2003) 8410-8416
9. Folstein M.F., Folstein S.E., and McHugh P.R. Mini-mental state: A practical method for grading the cognitive state of patients for the clinician. Journal of Psychiatric Research 12 (1975) 189-198
10. Grady C.L., Maisog J.M., Horwitz B., Ungerleider L.G., Mentis M.J., Salerno J.A., et al. Age-related changes in cortical blood flow activation during visual processing of faces and location. Journal of Neuroscience 14 (1994) 1450-1462
11. Grady C.L., Springer M.V., Hongwanishkul D., McIntosh A.R., and Winocur G. Age-related changes in brain activity across the adult lifespan. Journal of Cognitive Neuroscience 18 (2006) 227-241
12. Han S.D., Houston W.S., Jak A.J., Eyler L.T., Nagel B.J., Fleisher A.S., Brown G.G., Corey-Bloom J., Salmon D.P., Thal L.J., and Bondi M.W. Verbal paired-associate learning by APOE genotype in non-demented older adults: fMRI evidence of a right hemispheric compensatory response. Neurobiology of Aging 28 2 (2007) 238-247
13. He Y., Wang L., Zang Y., Tian L., Zhang X., Li K., et al. Regional coherence changes in the early stages of Alzheimer's disease: A combined structural and resting-state functional MRI study. Neuroimage 35 (2007) 488-500
14. Johnson K.A., Jones K., Holman B.L., Becker J.A., Spiers P.A., Satlin A., et al. Preclinical prediction of Alzheimer's disease using SPECT. Neurology 50 (1998) 1563-1571
15. Johnson S.C., Saykin A.J., Baxter L.C., Flashman L.A., Santulli R.B., McAllister T.W., et al. The relationship between fMRI activation and cerebral atrophy: Comparison of normal aging and Alzheimer disease. Neuroimage 11 (2000) 179-187
16. Kapur S., Craik F.I.M., Tulving E., Wilson A.A., Houle S., and Brown G.M. Neuroanatomical correlates of encoding in episodic memory: Levels of processing effect. Proceedings of the National Academy of Sciences in the United States of America 91 (1994) 2008-2011
17. Kogure D., Matsuda H., Ohnishi T., Asada T., Uno M., Kunihiro T., et al. Longitudinal evaluation of early Alzheimer's disease using brain perfusion SPECT. Journal of Nuclear Medicine 41 (2000) 1155-1162
18. Lind J., Ingvar M., Persson J., Sleegers K., Van Broeckhoven C., Adolfsson R., et al. Parietal cortex activation predicts memory decline in apolipoprotein E-epsilon4 carriers. Neuroreport 17 (2006) 1683-1686
19. Lind J., Larsson A., Persson J., Ingvar M., Nilsson L.G., Backman L., et al. Reduced hippocampal volume in non-demented carriers of the apolipoprotein E varepsilon4: Relation to chronological age and recognition memory. Neuroscience Letters 396 (2006) 23-27
20. Lind J., Persson J., Ingvar C.M., Larsson A., Cruts M., Van Broeckhoven C., et al. Cognitively intact carriers of the Apolipoprotein E4 show reduced functional brain activity response. Brain 129 (2006) 1240-1248
21. Lustig C., Snyder A.Z., Bhakta M., O'Brien K.C., McAvoy M., Raichle M.E., et al. Functional deactivations: Change with age and dementia of the Alzheimer type. Proceedings of the National Academy of Sciences in the United States of America 100 (2003) 14504-14509
22. Matsuda H. Cerebral blood flow and metabolic abnormalities in Alzheimer's disease. Annals of Nuclear Medicine 15 (2001) 85-92
23. Mazoyer B., Zago L., Mellet E., Bricogne S., Etard O., Houdé O., et al. Cortical networks for working memory and executive functions sustain the conscious resting state in man. Brain Research Bulletin 54 (2001) 287-298
24. McKiernan K.A., Kaufman J.N., Kucera-Thompson J., and Binder J.R. A parametric modulation of factors affecting task-induced deactivation in functional neuroimaging. Journal of Cognitive Neuroscience 15 (2003) 394-408
25. Meguro K., Blaizot X., Kondoh Y., Le Mestric C., Baron J.C., and Chavoix C. Neocortical and hippocampal glucose hypometabolism following neurotoxic lesions of the entorhinal and perirhinal cortices in the non-human primate as shown by PET. Implications for Alzheimer's disease. Brain 122 (1999) 1519-1531
26. Minoshima S., Foster N.L., and Kuhl D.E. Posterior cingulate cortex in Alzheimer's disease. Lancet 344 (1994) 895
27. Minoshima S., Giordani B., Berent S., Frey K.A., Foster N.L., and Kuhl D.E. Metabolic reduction in the posterior cingulate cortex in very early Alzheimer's disease. Annals of Neurology 42 (1997) 85-94
28. Nilsson L.-G., Bäckman L., Erngrund K., Nyberg L., Adolfsson R., Bucht G., et al. The Betula prospective cohort study: Memory, health and aging. Aging Neuropsychology and Cognition 4 (1997) 1-32
29. Nilsson L.-G., Adolfsson R., Bäckman L., de Frias C., Molander B., and Nyberg L. Betula: A prospective cohort study on memory, health, and aging. Aging, Neuropsychology and Cognition 11 (2004) 134-148
30. Persson J., Lind J., Larsson A., Ingvar C.M., Cruts M., Van Broeckhoven C., et al. Altered brain white matter integrity in healthy carriers of the APOE ε4 allele: A risk for AD?. Neurology 66 (2006) 1029-1033
31. Persson J., Lustig C., Nelson J.K., and Reuter-Lorenz P. Age differences in deactivation: A link to cognitive control?. Journal of Cognitive Neuroscience 19 (2007) 1021-1032
32. Persson J., Nyberg L., Lind J., Larsson A., Nilsson L.G., Ingvar M., et al. Structure-function correlates of cognitive decline in aging. Cerebral Cortex 16 (2006) 907-915
33. Raichle M.E., MacLeod A.M., Snyder A.Z., Powers W.J., Gusnard D.A., and Shulman G.L. A default mode of brain function. Proceedings of the National Academy of Sciences in the United States America 98 (2001) 676-682
34. Reed L.J., Marsden P., Lasserson D., Sheldon N., Lewis P., Stanhope N., et al. FDG-PET analysis and findings in amnesia resulting from hypoxia. Memory 7 (1999) 599-612
35. Reiman E.M., Caselli R.J., Yun L.S., Chen K., Bandy D., Minoshima S., et al. Preclinical evidence of Alzheimer's disease in persons homozygous for the epsilon 4 allele for apolipoprotein E. New England Journal of Medicine 334 (1996) 752-758
36. Reuter-Lorenz P.A., Jonides J., Smith E.E., Hartley A., Miller A., Marshuetz C., et al. Age differences in the frontal lateralization of verbal and spatial working memory revealed by PET. Journal of Cognitive Neuroscience 12 (2000) 174-187
37. Rombouts S.A., Barkhof F., Goekoop R., Stam C.J., and Scheltens P. Altered resting state networks in mild cognitive impairment and mild Alzheimer's disease: An fMRI study. Human Brain Mapping 26 (2005) 231-239
38. Shulman G.L., Fiez J.A., Corbetta M., Buckner R.L., Miezin F.M., Raichle M.E., et al. Common blood flow changes across visual tasks. II. Decreases in cerebral cortex. Journal of Cognitive Neuroscience 9 (1997) 648-663
39. Small G.W., Ercoli L.M., Silverman D.H., Huang S.C., Komo S., Bookheimer S.Y., et al. Cerebral metabolic and cognitive decline in persons at genetic risk for Alzheimer's disease. Proceedings of the National Academy of Sciences in the United States of America 97 (2000) 6037-6042
40. Smith C.D., Andersen A.H., Kryscio R.J., Schmitt F.A., Kindy M.S., Blonder L.X., et al. Altered brain activation in cognitively intact individuals at high risk for Alzheimer's disease. Neurology 53 (1999) 1391
41. Strittmatter W.J., Saunders A.M., Schmechel D., Pericak-Vance M., Enghild J., Salvesen G.S., et al. Apolipoprotein E: High-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. Proceedings of the National Academy of Sciences in the United States of America 90 (1993) 1977-1981