β-Amyloid (Aβ) deposition in the brains of aged orangutans

Neurobiology of Aging

Volumn 18, Issue 2, 1997, Pages 139-146

  Gearing, M ^a   Tigges, J ^a   Mori, H ^b   Mirra, Suzanne S ^a,c  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

^c ATLANTA VA MEDICAL CENTER   (United States)

Author keywords

Aging Senile plaque; Alzheimer's disease; Amyloid Apolipoprotein E; Great ape; Nonhuman primate; Orangutan

Indexed keywords

AMYLOID BETA PROTEIN; APOLIPOPROTEIN E;

AGED; AGING; ALZHEIMER DISEASE; ARTICLE; CONTROLLED STUDY; HISTOPATHOLOGY; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; NONHUMAN; ORANG UTAN; PRIORITY JOURNAL; SENILE PLAQUE;

AGING; AMYLOID BETA-PROTEIN; ANIMALS; BRAIN; BRAIN CHEMISTRY; CEREBRAL CORTEX; COLORING AGENTS; FEMALE; IMMUNOHISTOCHEMISTRY; MALE; NEUROFIBRILLARY TANGLES; PONGO PYGMAEUS;

EID: 0030833582     PISSN: 01974580     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0197-4580(97)00012-2     Document Type: Article

References (35)

1. Bowden, D. M.; Williams, D. D. Aging. Adv. Vet. Sci. Comp. Med. 28:305-341; 1984.
2. Cork, L. C.; Walker, L. C. Age-related lesions, nervous system. In: Jones, T. C.; Mohr, U.; Hunt, R. D., eds. Nonhuman primates II. Berlin: Springer Verlag; 1993; 173-183.
3. 40: Evidence from cats and dogs. Neurobiol. Aging 17:653-659; 1996.
4. Fukumoto, H.; Asami-Odaka, A.; Suzuki, N.; Shimada, H.; Ihara, Y.; Iwatsubo, T. Amyloid β protein deposition in normal aging has the same characteristics as that in Alzheimer's disease. Prominence of Aβ42(43) and association of Aβ40 with cored plaques. Am. J. Pathol. 148:259-265; 1996.
5. Gearing, M.; Mori, H.; Mirra, S. S. Aβ peptide length and apolipoprotein E genotype in Alzheimer's disease. Ann. Neurol. 39:395-399; 1996.
6. Gearing, M.; Rebeck, G. W.; Hyman, B. T.; Tigges, J.; Mirra, S. S. Neuropathology and apolipoprotein E profile of aged chimpanzees: Implications for Alzheimer disease. Proc. Natl. Acad. Sci. USA 91:9382-9386; 1994.
7. 40 is a major form of β-amyloid in nonhuman primates. Neurobiol. Aging 17:903-908; 1996.
8. Greenberg, S. M.; Rebeck, G. W.; Vonsattel, J. P. G.; Gomez-Isla, T.; Hyman, B. T. Apolipoprotein E ∈4 and cerebral hemorrhage associated with amyloid angiopathy. Ann. Neurol. 38:254-259; 1995.
9. Guilloud, M. B.; McClure, H. M. Air sac infection in the orang-utan (Pongo-pygmaeus). Recent Adv. Primatol. 3:143-147; 1969.
10. Iwatsubo, T.; Mann, D. M. A.; Odaka, A.; Suzuki, N.; Ihara, Y. Amyloid β protein (Aβ) deposition: Aβ42(43) precedes Aβ40 in Down syndrome. Ann. Neurol. 37:294-299; 1995.
11. Iwatsubo, T.; Odaka, A.; Suzuki, N.; Mizusawa, H.; Nukina, N.; Ihara, Y. Visualization of Aβ42(43) and Aβ40 in senile plaques with end-specific Aβ monoclonals: Evidence that an initially deposited species is Aβ42(43). Neuron 13:45-53; 1994.
12. Jarrett, J. T.; Lansbury, P. T., Jr. Seeding "one-dimensional crystallization" of amyloid: A pathogenic mechanism in Alzheimer's disease and scrapie? Cell 73:1055-1058; 1993.
13. Maggio, J. E.; Stimson, E. R.; Ghilardi, J. R.; Allen, C. J.; Dahl, C. E.; Whitcomb, D. C.; Vigna, S. R.; Vinters, H. V.; Labenski, M. E.; Mantyh, P. W. Reversible in vitro growth of Alzheimer disease β-amyloid plaques by deposition of labeled amyloid peptide. Proc. Natl. Acad. Sci. USA 89:5462-5466; 1992.
14. Mak, K.; Yang, F.; Vinters, H. V.; Frautschy, S. A.; Cole, G. M. Polyclonals to β-amyloid(1-42) identify most plaque and vascular deposits in Alzheimer cortex, but not striatum. Brain Res. 667:138-142; 1994.
15. Miyamoto, M. M.; Koop, B. F.; Slightom, J. L.; Goodman, M.; Tennant, M. R. Molecular systematics of higher primates: Genealogical relations and classification. Proc. Natl. Acad. Sci. USA 85:7627-7631; 1988.
16. 42 in the cerebrospinal fluid of patients with Alzheimer's disease. Ann. Neurol. 38:634-648; 1995.
17. Mufson, E. J.; Benzing, W. C.; Cole, G. M.; Wang, H.; Emerich, D. F.; Sladek, J. R., Jr.; Morrison, J. H.; Kordower, J. H. Apolipoprotein E-immunoreactivity in aged rhesus monkey cortex: Colocalization with amyloid plaques. Neurobiol. Aging 15:621-627; 1994.
18. Poduri, A.; Gearing, M.; Rebeck, G. W.; Mirra, S. S.; Tigges, J.; Hyman, B. T. Apolipoprotein E4 and beta amyloid in senile plaques and cerebral blood vessels of aged rhesus monkeys. Am. J. Pathol. 144:1183-1187; 1994.
19. Price, D. L.; Martin, L. J.; Sisodia, S. S.; Wagster, M. V.; Koo, E. H.; Walker, L. C.; Koliatsos, V. E.; Cork, L. C. Aged non-human primates: An animal model of age-associated neurodegenerative disease. Brain Pathol. 1:287-296; 1991.
20. Rebeck, G. W.; Reiter, J. S.; Strickland, D. K.; Hyman, B. T. Apolipoprotein E in sporadic Alzheimer's disease: Allelic variation and receptor interactions. Neuron 11:575-580; 1993.
21. Roher, A. E.; Lowenson, J. D.; Clarke, S.; Woods, A. S.; Cotter, R. J.; Gowing, E.; Ball, M. J. β-Amyloid-(1-42) is a major component of cerebrovascular amyloid deposits: Implications for the pathology of Alzheimer disease. Proc. Natl. Acad. Sci. USA 90:10836-10840; 1993.
22. Ruvolo, M.; Pan, D.; Zehr, S.; Goldberg, T.; Disotell, T. R.; von Dornum, M. Gene trees and hominoid phylogeny. Proc. Natl. Acad. Sci. USA 91:8900-8904; 1994.
23. 42 in cerebrovascular deposits. Amyloid Int. J. Exp. Clin. Invest. 2:234-240; 1995.
24. Scheuner, D.; Eckman, C.; Jensen, M.; Song, X.; Citron, M.; Suzuki, N.; Bird, T. D.; Hardy, J.; Hutton, M.; Kukull, W.; Larson, E.; Levy-Lahad, E.; Viitanen, M.; Peskind, E.; Poorkaj, P.; Schellenberg, G.; Tanzi, R.; Wasco, W.; Lannfelt, L.; Selkoe, D.; Younkin, S. Secreted amyloid β-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease. Nat. Med. 2:864-870; 1996.
25. Schmechel, D. E.; Saunders, A. M.; Strittmatter, W. J.; Crain, B. J.; Hulette, C. M.; Joo, S. H.; Pericak-Vance, M. A.; Goldgaber, D.; Roses, A. D. Increased amyloid β-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease. Proc. Natl. Acad. Sci. USA 90:9649-9653; 1993.
26. Selkoe, D. J.; Bell, D. S.; Podlisny, M. B.; Price, D. L.; Cork, L. C. Conservation of brain amyloid proteins in aged mammals and humans with Alzheimer's disease. Science 235:873-877; 1987.
27. Strittmatter, W. J.; Saunders, A. M.; Schmechel, D.; Pericak-Vance, M.; Enghild, J.; Salvesen, G. S.; Roses, A. D. Apolipoprotein E: High avidity binding to β-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. Proc. Natl. Acad. Sci. USA 90:1977-1981; 1993.
28. 717) mutants. Science 264:1336-1340; 1994.
29. 1-42/43) of amyloid β protein as a seed molecule in cerebral deposits of Alzheimer's disease. Biochem. Biophys. Res. Commun. 205:834-842; 1994.
30. Tamaoka, A.; Odaka, A.; Ishibashi, Y.; Usami, M.; Sahara, N.; Suzuki, N.; Nukina, N.; Mizusawa, H.; Shoji, S.; Kanazawa, I.; Mori, H. APP717 missense mutation affects the ratio of amyloid β protein species (Aβ1-42/43 and Aβ1-40) in familial Alzheimer's disease brain. J. Biol. Chem. 269:32721-32724; 1994.
31. Tekirian, T. L.; Cole, G. M.; Russell, M. J.; Yang, F.; Wekstein, D. R.; Patel, E.; Snowdon, D. A.; Markesbery, W. R.; Geddes, J. W. Carboxy terminal of β-amyloid deposits in aged human, canine, and polar bear brains. Neurobiol. Aging 17:249-257; 1996.
32. Utermann, G.; Langenbeck, U.; Beisiegel, U.; Weber, W. Genetics of the apolipoprotein E system in man. Am. J. Hum. Genet. 32:339-347; 1980.
33. Wisniewski, T.; Lalowski, M.; Bobik, M.; Russell, M.; Strosznajder, J.; Frangione, B. Amyloid β 1-42 deposits do not lead to Alzheimer's neuritic plaques in aged dogs. Biochem. J. 313:575-580; 1996.
34. Younkin, S. G. Evidence that Aβ42 is the real culprit in Alzheimer's disease. Ann. Neurol. 37:287-288; 1995.
35. Zannis, V. I.; Nicolosi, R. J.; Jensen, E.; Breslow, J. L.; Hayes, K. C. Plasma and hepatic apoE isoproteins of nonhuman primates. Differences in apoE among humans, apes, and New and Old World monkeys. J. Lipid Res. 26:1421-1430; 1985.