Correlations between apolipoprotein E ε4 gene dose and brain-imaging measurements of regional hypometabolism

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 23, 2005, Pages 8299-8302

  Reiman, Eric M ^a,b,h,i   Chen, Kewei ^a,c,d,i   Alexander, Gene E ^d,i   Caselli, Richard J ^e,i   Bandy, Daniel ^a,i   Osborne, David ^e,i   Saunders, Ann M ^f,j   Hardy, John ^g,k  

^a BANNER GOOD SAMARITAN MEDICAL CENTER   (United States)

^b UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF ARIZONA   (United States)

^d ARIZONA STATE UNIVERSITY   (United States)

^e MAYO CLINIC   (United States)

^f DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g MAYO GRADUATE SCHOOL   (United States)

^h TRANSLATIONAL GENOMICS RESEARCH INSTITUTE   (United States)

ⁱ ARIZONA ALZHEIMER S CONSORTIUM   (United States)

^j GLAXOSMITHKLINE   (United States)

^k NATIONAL INSTITUTE ON AGING   (United States)

more..

Author keywords

Alzheimer's disease; Endophenotype; Genetics; Positron emission tomography

Indexed keywords

GLUCOSE;

ADULT; ALLELE; ALZHEIMER DISEASE; APOE EPSILON4 GENE; ARTICLE; BRAIN HYPOMETABOLISM; BRAIN METABOLISM; BRAIN REGION; CINGULATE GYRUS; COGNITION; COGNITIVE DEFECT; CONTROLLED STUDY; CORRELATION ANALYSIS; DEMENTIA; DNA MODIFICATION; FEMALE; FRONTAL CORTEX; GENE; GENE DOSAGE; GENETIC ASSOCIATION; GENETIC RISK; GENOTYPE; HETEROZYGOSITY; HETEROZYGOTE; HOMOZYGOSITY; HUMAN; MAJOR CLINICAL STUDY; MALE; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING; ONSET AGE; PARIETAL LOBE; PHENOTYPE; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; TEMPORAL CORTEX;

AGE OF ONSET; AGED; ALLELES; ALZHEIMER DISEASE; APOLIPOPROTEIN E4; APOLIPOPROTEINS E; BRAIN; FEMALE; GENE DOSAGE; GENOTYPE; GLUCOSE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; METABOLIC DISEASES; MIDDLE AGED; PHENOTYPE; POSITRON-EMISSION TOMOGRAPHY;

EID: 20444395466     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0500579102     Document Type: Article

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