Age at onset of dementia and age of menopause in women with Down's syndrome

Journal of Intellectual Disability Research

Volumn 43, Issue 6, 1999, Pages 461-465

  Cosgrave, Mary P ^a,b,c   Tyrrell, J ^a   McCarron, M ^a   Gill, M ^a   Lawlor, B A ^a,b  

^a TRINITY COLLEGE DUBLIN   (Ireland)

^b ST JAMES S HOSPITAL   (Ireland)

^c ST PATRICK S HOSPITAL   (Ireland)

Author keywords

Alzheimer's disease; Correlation; Dementia; Down's syndrome; Menopause

Indexed keywords

ESTROGEN;

ADULT; AGING; ALZHEIMER DISEASE; ARTICLE; DEMENTIA; DOWN SYNDROME; ESTROGEN DEFICIENCY; FEMALE; HUMAN; IRELAND; MAJOR CLINICAL STUDY; MENOPAUSE; ONSET AGE; RISK FACTOR;

ADULT; AGE OF ONSET; ALZHEIMER DISEASE; ANALYSIS OF VARIANCE; DEMENTIA; DOWN SYNDROME; ESTROGENS; FEMALE; HUMANS; IRELAND; MENOPAUSE; MIDDLE AGED; POSTMENOPAUSE; PROSPECTIVE STUDIES;

EID: 0033458868     PISSN: 09642633     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2788.1999.00192.x     Document Type: Article

References (21)

1. Armstrong R. A., Cairns N. J., Myers D., Smith C. U. M., Lantos P. L. & Rossor M. N. (1996) A comparison of beta-amyloid deposition in the medial temporal lobe in sporadic Alzheimer's disease, Down's syndrome and normal elderly brains. Neurodegeneration 5, 35-41.
2. Aylward E., Burt D., Thorpe L., Lai F. & Dalton A. (1997) Diagnosis of dementia in individuals with intellectual disability. Journal of Intellectual Deficiency Research 41, 152-64.
3. Carr J. & Hollins J. (1995) Menopause in women with learning disabilities. Journal of Intellectual Deficiency Research 39, 137-9.
4. Fraser J. & Mitchell A. (1876) Kalmuc idiocy: report of a case with autopsy with notes on 62 cases. Journal of Mental Science 22, 161.
5. Jeune B. (1986) Parity and age at menopause in a Danish sample. Maturitas 8, 359-65.
6. Kawas C., Resnick S., Morrison A., Brookmeyer R., Corrada M., Zonderman A., Bacal C., Donnell Lingle D. & Metter E. (1997) A prospective study of estrogen replacement therapy and the risk of developing Alzheimer's disease. Neurology 48, 1517-21.
7. Mackay E. B., Beischer N. A., Cox L. W. & Wood C. (1983) Illustrated Textbook of Gynaecology, pp. 85. Artarmon Saunders, NSW.
8. Martin G. M. (1978) Genetic syndromes in man with potential relevance to pathobiology of aging. In: Genetic Effects on Aging, Birth Defect: Original Articles, Vol. XIV (eds D. Bergsma & D. E. Harrisons), pp. 5-39. New York, NY.
9. Niki E. & Nakano M. (1990) Estrogens as antioxidants. Methods in Enzymology 186, 330-3.
10. Oliver C. & Holland A. J. (1986) Down's syndrome and Alzheimer's disease: a review. Psychological Medicine 16, 307-22.
11. Paganini-Hill A. & Henderson V. (1996) Estrogen replacement therapy and the risk of Alzheimer disease. Archives of Internal Medicine 24, 137-41.
12. Pary R. (1992) Differential diagnosis of functional decline in Down's Syndrome. Habilitative Mental Healthcare Newsletter II, 37-41.
13. Prasher V. P. (1995) Age-specific prevalence, thyroid dysfunction and depressive symptomatology in adults with Down syndrome and dementia. International Journal of Geriatric Psychiatry 10, 25-31.
14. Prasher V. P. & Krishna V. H. R. (1993) Age on onset and duration of dementia in people with Down syndrome: integration of 98 reported cases in literature. International Journal of Geriatric Psychiatry 8, 915-22.
15. Saunders A., Schmader K., Breitner J. S. C., Benson M. D., Brown W. T., Goldfarb L., Goldgaber D., Manwaring M. G., Szymanski M. H., McCowan N., Dole K. C., Schmechel D. E., Strittmatter W. J., Pericak-Vance M. A. & Roses A. D. (1993) Apolipoprotein E e4 allele distributions in late-onset Alzheimer's disease and other amyloid-forming diseases. Lancet 342, 710-11.
16. Schupf N., Zigman W., Kapell D., Lee J. H., Kline J. & Levin B. (1997) Early menopause in women with Down's syndrome. Journal of Intellectual Deficiency Research 41, 264-7.
17. Talbot C., Lendon C., Craddock N., Shears S., Morris J. & Goate A. (1994) Protection against Alzheimer's disease with ApoE e2. Lancet 343, 1432-3.
18. Tang M., Jacobs D., Stern Y., Marder K., Schofield P., Gurland B., Andrews H. & Mayeux R. (1996) Effect of oestrogen during menopause on risk and age at onset of Alzheimer's disease. Lancet 348, 429-32.
19. Tyrrell J., Cosgrave M., Hawi Z., McPherson J., O'Brien C., McCalvert J., McLaughlin M., Lawlor B. & Gill M. (1998) A protective effect of Apolipoprotein E e2 allele on dementia in Down's, syndrome. Biological Psychiatry 43, 397-400.
20. Visser F. E., Aldenkamp A. P., van Huffelen A. C., Kuilman M., Overweg J. & van Wijk J. (1997) Prospective study of the prevalence of Alzheimer-type dementia in institutionalized individuals with Down syndrome. American Journal on Mental Retardation 101, 400-12.
21. World Health Organization (WHO) (1992) The ICD-10 Classification of Mental and Behavioural Disorders. WHO, Geneva.