메뉴 건너뛰기




Volumn 10, Issue 5, 2010, Pages 359-366

Hormonal influences on cognition and risk for Alzheimer's disease

Author keywords

Alzheimer's Disease; Dementia; Estrogen; Genetics; Hormone Replacement Therapy

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE 1; AROMATASE; CONJUGATED ESTROGEN; CONJUGATED ESTROGEN PLUS MEDROXYPROGESTERONE ACETATE; CYTOCHROME P450 17; DIENOGEST; ESTRADIOL; ESTROGEN; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; GESTAGEN; PLACEBO; PROGESTERONE; RALOXIFENE; SELECTIVE ESTROGEN RECEPTOR MODULATOR; TAMOXIFEN; NEUROPROTECTIVE AGENT;

EID: 77956288455     PISSN: 15284042     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11910-010-0122-6     Document Type: Review
Times cited : (109)

References (78)
  • 1
    • 0029924284 scopus 로고    scopus 로고
    • Estrogens attenuate and corticosterone exacerbates excitotoxicity, oxidative injury, and amyloid beta-peptide toxicity in hippocampal neurons
    • 10.1046/j.1471-4159.1996.66051836.x 1:CAS:528:DyaK28XisVSkurs%3D 8780008
    • Y Goodman AJ Bruce B Cheng MP Mattson 1996 Estrogens attenuate and corticosterone exacerbates excitotoxicity, oxidative injury, and amyloid beta-peptide toxicity in hippocampal neurons J Neurochem 66 1836 1844 10.1046/j.1471-4159.1996.66051836.x 1:CAS:528:DyaK28XisVSkurs%3D 8780008
    • (1996) J Neurochem , vol.66 , pp. 1836-1844
    • Goodman, Y.1    Bruce, A.J.2    Cheng, B.3    Mattson, M.P.4
  • 2
    • 0026551310 scopus 로고
    • Estrogen receptors colocalize with low-affinity nerve growth factor receptors in cholinergic neurons of the basal forebrain
    • 10.1073/pnas.89.10.4668 1:CAS:528:DyaK38XktVWht74%3D 1316615
    • CD Toran-Allerand RC Miranda WD Bentham, et al. 1992 Estrogen receptors colocalize with low-affinity nerve growth factor receptors in cholinergic neurons of the basal forebrain Proc Natl Acad Sci U S A 89 4668 4672 10.1073/pnas.89.10.4668 1:CAS:528:DyaK38XktVWht74%3D 1316615
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 4668-4672
    • Toran-Allerand, C.D.1    Miranda, R.C.2    Bentham, W.D.3
  • 3
    • 0021861330 scopus 로고
    • Estradiol increases choline acetyltransferase activity in specific basal forebrain nuclei and projection areas of female rats
    • 10.1016/0014-4886(85)90108-6 1:CAS:528:DyaL2MXltFKnu70%3D 2990988
    • VN Luine 1985 Estradiol increases choline acetyltransferase activity in specific basal forebrain nuclei and projection areas of female rats Exp Neurol 89 484 490 10.1016/0014-4886(85)90108-6 1:CAS:528:DyaL2MXltFKnu70%3D 2990988
    • (1985) Exp Neurol , vol.89 , pp. 484-490
    • Luine, V.N.1
  • 4
    • 0028971169 scopus 로고
    • 17-beta estradiol protects neurons from oxidative stress-induced cell death in vitro
    • 10.1006/bbrc.1995.2647 1:CAS:528:DyaK2MXptlentLY%3D 7488136
    • C Behl M Widmann T Trapp F Holsboer 1995 17-beta estradiol protects neurons from oxidative stress-induced cell death in vitro Biochem Biophys Res Commun 216 473 482 10.1006/bbrc.1995.2647 1:CAS:528:DyaK2MXptlentLY%3D 7488136
    • (1995) Biochem Biophys Res Commun , vol.216 , pp. 473-482
    • Behl, C.1    Widmann, M.2    Trapp, T.3    Holsboer, F.4
  • 5
    • 0028342424 scopus 로고
    • Estrogen regulates metabolism of Alzheimer amyloid beta precursor protein
    • 1:CAS:528:DyaK2cXjtFKisbg%3D 8175728
    • AB Jaffe CD Toran-Allerand P Greengard SE Gandy 1994 Estrogen regulates metabolism of Alzheimer amyloid beta precursor protein J Biol Chem 269 13065 13068 1:CAS:528:DyaK2cXjtFKisbg%3D 8175728
    • (1994) J Biol Chem , vol.269 , pp. 13065-13068
    • Jaffe, A.B.1    Toran-Allerand, C.D.2    Greengard, P.3    Gandy, S.E.4
  • 6
    • 0032786697 scopus 로고    scopus 로고
    • Gender differences in the incidence of AD and vascular dementia: The EURODEM Studies. EURODEM Incidence Research Group
    • 1:STN:280:DC%2BD3c%2Fms1OmsQ%3D%3D 10599770
    • K Andersen LJ Launer ME Dewey, et al. 1999 Gender differences in the incidence of AD and vascular dementia: the EURODEM Studies. EURODEM Incidence Research Group Neurology 53 1992 1997 1:STN:280:DC%2BD3c%2Fms1OmsQ%3D%3D 10599770
    • (1999) Neurology , vol.53 , pp. 1992-1997
    • Andersen, K.1    Launer, L.J.2    Dewey, M.E.3
  • 7
    • 0031024278 scopus 로고    scopus 로고
    • Very old women at highest risk of dementia and Alzheimer's disease: Incidence data from the Kungsholmen Project, Stockholm
    • 1:STN:280:DyaK2s7mtFamsw%3D%3D 9008508
    • L Fratiglioni M Viitanen E von Strauss, et al. 1997 Very old women at highest risk of dementia and Alzheimer's disease: incidence data from the Kungsholmen Project, Stockholm Neurology 48 132 138 1:STN:280: DyaK2s7mtFamsw%3D%3D 9008508
    • (1997) Neurology , vol.48 , pp. 132-138
    • Fratiglioni, L.1    Viitanen, M.2    Von Strauss, E.3
  • 8
    • 0034646205 scopus 로고    scopus 로고
    • Ten-year incidence of dementia in a rural elderly US community population: The MoVIES Project
    • 1:STN:280:DC%2BD3c7otlahtw%3D%3D 10720283
    • M Ganguli HH Dodge P Chen, et al. 2000 Ten-year incidence of dementia in a rural elderly US community population: the MoVIES Project Neurology 54 1109 1116 1:STN:280:DC%2BD3c7otlahtw%3D%3D 10720283
    • (2000) Neurology , vol.54 , pp. 1109-1116
    • Ganguli, M.1    Dodge, H.H.2    Chen, P.3
  • 9
    • 0032127506 scopus 로고    scopus 로고
    • Incidence of dementia and Alzheimer's disease: A reanalysis of data from Rochester, Minnesota, 1975-1984
    • 1:STN:280:DyaK1czis1GgtQ%3D%3D 9663404
    • WA Rocca RH Cha SC Waring E Kokmen 1998 Incidence of dementia and Alzheimer's disease: a reanalysis of data from Rochester, Minnesota, 1975-1984 Am J Epidemiol 148 51 62 1:STN:280:DyaK1czis1GgtQ%3D%3D 9663404
    • (1998) Am J Epidemiol , vol.148 , pp. 51-62
    • Rocca, W.A.1    Cha, R.H.2    Waring, S.C.3    Kokmen, E.4
  • 10
    • 0027457545 scopus 로고
    • Incidence of dementia and probable Alzheimer's disease in a general population: The Framingham Study
    • 1:STN:280:DyaK3s7ps1yrsA%3D%3D 8450993
    • DL Bachman PA Wolf RT Linn, et al. 1993 Incidence of dementia and probable Alzheimer's disease in a general population: the Framingham Study Neurology 43 515 519 1:STN:280:DyaK3s7ps1yrsA%3D%3D 8450993
    • (1993) Neurology , vol.43 , pp. 515-519
    • Bachman, D.L.1    Wolf, P.A.2    Linn, R.T.3
  • 11
    • 0034643878 scopus 로고    scopus 로고
    • Age-specific incidence rates of Alzheimer's disease: The Baltimore Longitudinal Study of Aging
    • 1:STN:280:DC%2BD3czhtFGltQ%3D%3D 10851365
    • C Kawas S Gray R Brookmeyer, et al. 2000 Age-specific incidence rates of Alzheimer's disease: the Baltimore Longitudinal Study of Aging Neurology 54 2072 2077 1:STN:280:DC%2BD3czhtFGltQ%3D%3D 10851365
    • (2000) Neurology , vol.54 , pp. 2072-2077
    • Kawas, C.1    Gray, S.2    Brookmeyer, R.3
  • 12
    • 0029031466 scopus 로고
    • Age-specific incidence of Alzheimer's disease in a community population
    • 10.1001/jama.273.17.1354 1:STN:280:DyaK2M3jtVyksQ%3D%3D 7715060
    • LE Hebert PA Scherr LA Beckett, et al. 1995 Age-specific incidence of Alzheimer's disease in a community population JAMA 273 1354 1359 10.1001/jama.273.17.1354 1:STN:280:DyaK2M3jtVyksQ%3D%3D 7715060
    • (1995) JAMA , vol.273 , pp. 1354-1359
    • Hebert, L.E.1    Scherr, P.A.2    Beckett, L.A.3
  • 13
    • 0036845531 scopus 로고    scopus 로고
    • Dementia and Alzheimer disease incidence: A prospective cohort study
    • 10.1001/archneur.59.11.1737 12433261
    • WA Kukull R Higdon JD Bowen, et al. 2002 Dementia and Alzheimer disease incidence: a prospective cohort study Arch Neurol 59 1737 1746 10.1001/archneur.59.11.1737 12433261
    • (2002) Arch Neurol , vol.59 , pp. 1737-1746
    • Kukull, W.A.1    Higdon, R.2    Bowen, J.D.3
  • 14
    • 0344603632 scopus 로고    scopus 로고
    • Endogenous levels of dehydroepiandrosterone sulfate, but not other sex hormones, are associated with depressed mood in older women: The Rancho Bernardo Study
    • 1:CAS:528:DyaK1MXktFOhsLo%3D 10366167
    • E Barrett-Connor D von Muhlen GA Laughlin A Kripke 1999 Endogenous levels of dehydroepiandrosterone sulfate, but not other sex hormones, are associated with depressed mood in older women: the Rancho Bernardo Study J Am Geriatr Soc 47 685 691 1:CAS:528:DyaK1MXktFOhsLo%3D 10366167
    • (1999) J Am Geriatr Soc , vol.47 , pp. 685-691
    • Barrett-Connor, E.1    Von Muhlen, D.2    Laughlin, G.A.3    Kripke, A.4
  • 15
    • 0031911321 scopus 로고    scopus 로고
    • Cognitive function in nondemented older women who took estrogen after menopause
    • 1:CAS:528:DyaK1cXhslyqu7g%3D 9484355
    • DM Jacobs MX Tang Y Stern, et al. 1998 Cognitive function in nondemented older women who took estrogen after menopause Neurology 50 368 373 1:CAS:528:DyaK1cXhslyqu7g%3D 9484355
    • (1998) Neurology , vol.50 , pp. 368-373
    • Jacobs, D.M.1    Tang, M.X.2    Stern, Y.3
  • 16
    • 0028085516 scopus 로고
    • Estrogen deficiency and risk of Alzheimer's disease in women
    • 1:STN:280:DyaK2czgtlKlsg%3D%3D 8030628
    • A Paganini-Hill VW Henderson 1994 Estrogen deficiency and risk of Alzheimer's disease in women Am J Epidemiol 140 256 261 1:STN:280: DyaK2czgtlKlsg%3D%3D 8030628
    • (1994) Am J Epidemiol , vol.140 , pp. 256-261
    • Paganini-Hill, A.1    Henderson, V.W.2
  • 17
    • 0030591669 scopus 로고    scopus 로고
    • Effect of oestrogen during menopause on risk and age at onset of Alzheimer's disease
    • 10.1016/S0140-6736(96)03356-9 1:CAS:528:DyaK28XlsValtrc%3D 8709781
    • MX Tang D Jacobs Y Stern, et al. 1996 Effect of oestrogen during menopause on risk and age at onset of Alzheimer's disease Lancet 348 429 432 10.1016/S0140-6736(96)03356-9 1:CAS:528:DyaK28XlsValtrc%3D 8709781
    • (1996) Lancet , vol.348 , pp. 429-432
    • Tang, M.X.1    Jacobs, D.2    Stern, Y.3
  • 18
    • 0034718373 scopus 로고    scopus 로고
    • Cognitive decline in women in relation to non-protein-bound oestradiol concentrations
    • 10.1016/S0140-6736(00)02628-3 1:CAS:528:DC%2BD3cXmtlOgurY%3D 11085689
    • K Yaffe LY Lui D Grady, et al. 2000 Cognitive decline in women in relation to non-protein-bound oestradiol concentrations Lancet 356 708 712 10.1016/S0140-6736(00)02628-3 1:CAS:528:DC%2BD3cXmtlOgurY%3D 11085689
    • (2000) Lancet , vol.356 , pp. 708-712
    • Yaffe, K.1    Lui, L.Y.2    Grady, D.3
  • 19
    • 0037032401 scopus 로고    scopus 로고
    • Hormone replacement therapy and incidence of Alzheimer disease in older women: The Cache County Study
    • 10.1001/jama.288.17.2123 1:CAS:528:DC%2BD38XosVOjs7Y%3D 12413371
    • PP Zandi MC Carlson BL Plassman, et al. 2002 Hormone replacement therapy and incidence of Alzheimer disease in older women: the Cache County Study JAMA 288 2123 2129 10.1001/jama.288.17.2123 1:CAS:528:DC%2BD38XosVOjs7Y%3D 12413371
    • (2002) JAMA , vol.288 , pp. 2123-2129
    • Zandi, P.P.1    Carlson, M.C.2    Plassman, B.L.3
  • 20
    • 73949123417 scopus 로고    scopus 로고
    • Aging, estrogens and episodic memory in women
    • 10.1097/WNN.0b013e3181a74ce7 19996872
    • VW Henderson 2009 Aging, estrogens and episodic memory in women Cogn Behav Neurol 22 205 214 10.1097/WNN.0b013e3181a74ce7 19996872
    • (2009) Cogn Behav Neurol , vol.22 , pp. 205-214
    • Henderson, V.W.1
  • 21
    • 0037032405 scopus 로고    scopus 로고
    • Hormone therapy and risk of Alzheimer disease: A critical time
    • 10.1001/jama.288.17.2170 12413378
    • SM Resnick VW Henderson 2002 Hormone therapy and risk of Alzheimer disease: a critical time JAMA 288 2170 2172 10.1001/jama.288.17.2170 12413378
    • (2002) JAMA , vol.288 , pp. 2170-2172
    • Resnick, S.M.1    Henderson, V.W.2
  • 22
    • 33745235532 scopus 로고    scopus 로고
    • Estrogen therapy selectively enhances prefrontal cognitive processes: A randomized, double-blind, placebo-controlled study with functional magnetic resonance imaging in perimenopausal and recently postmenopausal women
    • 10.1097/01.gme.0000189618.48774.7b 16735938
    • H Joffe JE Hall S Gruber, et al. 2006 Estrogen therapy selectively enhances prefrontal cognitive processes: a randomized, double-blind, placebo-controlled study with functional magnetic resonance imaging in perimenopausal and recently postmenopausal women Menopause 13 411 422 10.1097/01.gme.0000189618.48774.7b 16735938
    • (2006) Menopause , vol.13 , pp. 411-422
    • Joffe, H.1    Hall, J.E.2    Gruber, S.3
  • 23
    • 0027102043 scopus 로고
    • Effects of estrogen on memory function in surgically menopausal women
    • 10.1016/0306-4530(92)90007-T 1:STN:280:DyaK3s7jtl2rtg%3D%3D 1484915
    • SM Phillips BB Sherwin 1992 Effects of estrogen on memory function in surgically menopausal women Psychoneuroendocrinology 17 485 495 10.1016/0306-4530(92)90007-T 1:STN:280:DyaK3s7jtl2rtg%3D%3D 1484915
    • (1992) Psychoneuroendocrinology , vol.17 , pp. 485-495
    • Phillips, S.M.1    Sherwin, B.B.2
  • 24
    • 0023770991 scopus 로고
    • Estrogen and/or androgen replacement therapy and cognitive functioning in surgically menopausal women
    • 10.1016/0306-4530(88)90060-1 1:STN:280:DyaL1M7ksFCgsw%3D%3D 3067252
    • BB Sherwin 1988 Estrogen and/or androgen replacement therapy and cognitive functioning in surgically menopausal women Psychoneuroendocrinology 13 345 357 10.1016/0306-4530(88)90060-1 1:STN:280:DyaL1M7ksFCgsw%3D%3D 3067252
    • (1988) Psychoneuroendocrinology , vol.13 , pp. 345-357
    • Sherwin, B.B.1
  • 25
    • 27744445643 scopus 로고    scopus 로고
    • A 20-week randomized controlled trial of estradiol replacement therapy for women aged 70 years and older: Effect on mood, cognition and quality of life
    • 10.1016/j.neurobiolaging.2004.12.012 1:CAS:528:DC%2BD2MXht1egsr3P 16298249
    • OP Almeida NT Lautenschlager S Vasikaran, et al. 2006 A 20-week randomized controlled trial of estradiol replacement therapy for women aged 70 years and older: effect on mood, cognition and quality of life Neurobiol Aging 27 141 149 10.1016/j.neurobiolaging.2004.12.012 1:CAS:528:DC%2BD2MXht1egsr3P 16298249
    • (2006) Neurobiol Aging , vol.27 , pp. 141-149
    • Almeida, O.P.1    Lautenschlager, N.T.2    Vasikaran, S.3
  • 26
    • 13244256993 scopus 로고    scopus 로고
    • Short-term transdermal estradiol therapy, cognition and depressive symptoms in healthy older women. A randomised placebo controlled pilot cross-over study
    • 10.1016/j.psyneuen.2004.08.007 1:CAS:528:DC%2BD2MXptlGntQ%3D%3D 15694110
    • R Schiff CJ Bulpitt KA Wesnes C Rajkumar 2005 Short-term transdermal estradiol therapy, cognition and depressive symptoms in healthy older women. A randomised placebo controlled pilot cross-over study Psychoneuroendocrinology 30 309 315 10.1016/j.psyneuen.2004.08.007 1:CAS:528:DC%2BD2MXptlGntQ%3D%3D 15694110
    • (2005) Psychoneuroendocrinology , vol.30 , pp. 309-315
    • Schiff, R.1    Bulpitt, C.J.2    Wesnes, K.A.3    Rajkumar, C.4
  • 27
    • 0032805059 scopus 로고    scopus 로고
    • Two weeks of transdermal estradiol treatment in postmenopausal elderly women and its effect on memory and mood: Verbal memory changes are associated with the treatment induced estradiol levels
    • 10.1016/S0306-4530(99)00025-6 1:CAS:528:DyaK1MXltlOmsbc%3D 10451908
    • OT Wolf BM Kudielka DH Hellhammer, et al. 1999 Two weeks of transdermal estradiol treatment in postmenopausal elderly women and its effect on memory and mood: verbal memory changes are associated with the treatment induced estradiol levels Psychoneuroendocrinology 24 727 741 10.1016/S0306-4530(99)00025-6 1:CAS:528:DyaK1MXltlOmsbc%3D 10451908
    • (1999) Psychoneuroendocrinology , vol.24 , pp. 727-741
    • Wolf, O.T.1    Kudielka, B.M.2    Hellhammer, D.H.3
  • 28
    • 34748925938 scopus 로고    scopus 로고
    • Hormone therapy in menopausal women with cognitive complaints: A randomized, double-blind trial
    • 10.1212/01.wnl.0000277275.42504.93 1:CAS:528:DC%2BD2sXhtVKhsrbN 17893293
    • PM Maki MJ Gast AJ Vieweg, et al. 2007 Hormone therapy in menopausal women with cognitive complaints: a randomized, double-blind trial Neurology 69 1322 1330 10.1212/01.wnl.0000277275.42504.93 1:CAS:528:DC%2BD2sXhtVKhsrbN 17893293
    • (2007) Neurology , vol.69 , pp. 1322-1330
    • Maki, P.M.1    Gast, M.J.2    Vieweg, A.J.3
  • 29
    • 0035071467 scopus 로고    scopus 로고
    • Double-blind, placebo-controlled psychometric studies on the effects of a combined estrogen-progestin regimen versus estrogen alone on performance, mood and personality of menopausal syndrome patients
    • 1:CAS:528:DC%2BD3MXivVCkt7Y%3D 11304940
    • L Linzmayer HV Semlitsch B Saletu, et al. 2001 Double-blind, placebo-controlled psychometric studies on the effects of a combined estrogen-progestin regimen versus estrogen alone on performance, mood and personality of menopausal syndrome patients Arzneimittelforschung 51 238 245 1:CAS:528:DC%2BD3MXivVCkt7Y%3D 11304940
    • (2001) Arzneimittelforschung , vol.51 , pp. 238-245
    • Linzmayer, L.1    Semlitsch, H.V.2    Saletu, B.3
  • 30
    • 33847289250 scopus 로고    scopus 로고
    • The effect of 3-year treatment with 0.25 mg/day of micronized 17beta-estradiol on cognitive function in older postmenopausal women
    • 10.1111/j.1532-5415.2007.01085.x 17341247
    • MA Pefanco AM Kenny RF Kaplan, et al. 2007 The effect of 3-year treatment with 0.25 mg/day of micronized 17beta-estradiol on cognitive function in older postmenopausal women J Am Geriatr Soc 55 426 431 10.1111/j.1532-5415.2007.01085. x 17341247
    • (2007) J Am Geriatr Soc , vol.55 , pp. 426-431
    • Pefanco, M.A.1    Kenny, A.M.2    Kaplan, R.F.3
  • 31
    • 33646407283 scopus 로고    scopus 로고
    • Effects of combination estrogen plus progestin hormone treatment on cognition and affect
    • 10.1210/jc.2005-2097 1:CAS:528:DC%2BD28XkslCntb8%3D 16522699
    • SM Resnick PM Maki SR Rapp, et al. 2006 Effects of combination estrogen plus progestin hormone treatment on cognition and affect J Clin Endocrinol Metab 91 1802 1810 10.1210/jc.2005-2097 1:CAS:528:DC%2BD28XkslCntb8%3D 16522699
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 1802-1810
    • Resnick, S.M.1    Maki, P.M.2    Rapp, S.R.3
  • 32
    • 0036851506 scopus 로고    scopus 로고
    • Effect of postmenopausal hormone therapy on cognitive function: The Heart and Estrogen/Progestin Replacement Study
    • 10.1016/S0002-9343(02)01270-6 1:CAS:528:DC%2BD38XovFGqtbc%3D 12459399
    • D Grady K Yaffe M Kristof, et al. 2002 Effect of postmenopausal hormone therapy on cognitive function: the Heart and Estrogen/Progestin Replacement Study Am J Med 113 543 548 10.1016/S0002-9343(02)01270-6 1:CAS:528: DC%2BD38XovFGqtbc%3D 12459399
    • (2002) Am J Med , vol.113 , pp. 543-548
    • Grady, D.1    Yaffe, K.2    Kristof, M.3
  • 33
    • 0032430616 scopus 로고    scopus 로고
    • The Women's Health Initiative Memory Study (WHIMS): A trial of the effect of estrogen therapy in preventing and slowing the progression of dementia
    • 10.1016/S0197-2456(98)00038-5 1:STN:280:DyaK1M%2FptFSnsQ%3D%3D 9875839
    • SA Shumaker BA Reboussin MA Espeland, et al. 1998 The Women's Health Initiative Memory Study (WHIMS): a trial of the effect of estrogen therapy in preventing and slowing the progression of dementia Control Clin Trials 19 604 621 10.1016/S0197-2456(98)00038-5 1:STN:280:DyaK1M%2FptFSnsQ%3D%3D 9875839
    • (1998) Control Clin Trials , vol.19 , pp. 604-621
    • Shumaker, S.A.1    Reboussin, B.A.2    Espeland, M.A.3
  • 34
    • 0038386058 scopus 로고    scopus 로고
    • Estrogen plus progestin and the incidence of dementia and mild cognitive impairment in postmenopausal women: The Women's Health Initiative Memory Study: A randomized controlled trial
    • 10.1001/jama.289.20.2651 1:CAS:528:DC%2BD3sXktVCqs7w%3D 12771112
    • SA Shumaker C Legault SR Rapp, et al. 2003 Estrogen plus progestin and the incidence of dementia and mild cognitive impairment in postmenopausal women: the Women's Health Initiative Memory Study: a randomized controlled trial JAMA 289 2651 2662 10.1001/jama.289.20.2651 1:CAS:528:DC%2BD3sXktVCqs7w%3D 12771112
    • (2003) JAMA , vol.289 , pp. 2651-2662
    • Shumaker, S.A.1    Legault, C.2    Rapp, S.R.3
  • 35
    • 2942755831 scopus 로고    scopus 로고
    • Conjugated equine estrogens and incidence of probable dementia and mild cognitive impairment in postmenopausal women: Women's Health Initiative Memory Study
    • 10.1001/jama.291.24.2947 1:CAS:528:DC%2BD2cXltFKjsLw%3D 15213206
    • SA Shumaker C Legault L Kuller, et al. 2004 Conjugated equine estrogens and incidence of probable dementia and mild cognitive impairment in postmenopausal women: Women's Health Initiative Memory Study JAMA 291 2947 2958 10.1001/jama.291.24.2947 1:CAS:528:DC%2BD2cXltFKjsLw%3D 15213206
    • (2004) JAMA , vol.291 , pp. 2947-2958
    • Shumaker, S.A.1    Legault, C.2    Kuller, L.3
  • 36
    • 0042337371 scopus 로고    scopus 로고
    • Divergent impact of progesterone and medroxyprogesterone acetate (Provera) on nuclear mitogen-activated protein kinase signaling
    • 10.1073/pnas.1334098100 1:CAS:528:DC%2BD3sXntFynsLg%3D 12925744
    • J Nilsen RD Brinton 2003 Divergent impact of progesterone and medroxyprogesterone acetate (Provera) on nuclear mitogen-activated protein kinase signaling Proc Natl Acad Sci USA 100 10506 10511 10.1073/pnas.1334098100 1:CAS:528:DC%2BD3sXntFynsLg%3D 12925744
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 10506-10511
    • Nilsen, J.1    Brinton, R.D.2
  • 37
    • 59349103299 scopus 로고    scopus 로고
    • A multi-center, randomized, double blind placebo-controlled trial of estrogens to prevent Alzheimer's disease and loss of memory in women: Design and baseline characteristics
    • 10.1177/1740774508096313 18827045
    • M Sano D Jacobs H Andrews, et al. 2008 A multi-center, randomized, double blind placebo-controlled trial of estrogens to prevent Alzheimer's disease and loss of memory in women: design and baseline characteristics Clin Trials 5 523 533 10.1177/1740774508096313 18827045
    • (2008) Clin Trials , vol.5 , pp. 523-533
    • Sano, M.1    Jacobs, D.2    Andrews, H.3
  • 38
    • 68749108089 scopus 로고    scopus 로고
    • Using basic science to design a clinical trial: Baseline characteristics of women enrolled in the Kronos Early Estrogen Prevention Study (KEEPS)
    • 10.1007/s12265-009-9104-y 1:STN:280:DC%2BC3crhtFGluw%3D%3D 19668346
    • VM Miller DM Black EA Brinton, et al. 2009 Using basic science to design a clinical trial: baseline characteristics of women enrolled in the Kronos Early Estrogen Prevention Study (KEEPS) J Cardiovasc Transl Res 2 228 239 10.1007/s12265-009-9104-y 1:STN:280:DC%2BC3crhtFGluw%3D%3D 19668346
    • (2009) J Cardiovasc Transl Res , vol.2 , pp. 228-239
    • Miller, V.M.1    Black, D.M.2    Brinton, E.A.3
  • 40
    • 0031818145 scopus 로고    scopus 로고
    • Serum estrogen levels, cognitive performance, and risk of cognitive decline in older community women
    • 1:CAS:528:DyaK1cXkslSltLc%3D 9670866
    • K Yaffe D Grady A Pressman S Cummings 1998 Serum estrogen levels, cognitive performance, and risk of cognitive decline in older community women J Am Geriatr Soc 46 816 821 1:CAS:528:DyaK1cXkslSltLc%3D 9670866
    • (1998) J Am Geriatr Soc , vol.46 , pp. 816-821
    • Yaffe, K.1    Grady, D.2    Pressman, A.3    Cummings, S.4
  • 41
    • 22044440465 scopus 로고    scopus 로고
    • Endogenous oestrogens are related to cognition in healthy elderly women
    • 10.1111/j.1365-2265.2005.02297.x 1:CAS:528:DC%2BD2MXnt1ylsrc%3D
    • CE Lebrun YT van der Schouw FH de Jong, et al. 2005 Endogenous oestrogens are related to cognition in healthy elderly women Clin Endocrinol (Oxf) 63 50 55 10.1111/j.1365-2265.2005.02297.x 1:CAS:528:DC%2BD2MXnt1ylsrc%3D
    • (2005) Clin Endocrinol (Oxf) , vol.63 , pp. 50-55
    • Lebrun, C.E.1    Van Der Schouw, Y.T.2    De Jong, F.H.3
  • 42
    • 0141646636 scopus 로고    scopus 로고
    • Onset of dementia is associated with age at menopause in women with Down's syndrome
    • 10.1002/ana.10677 14520653
    • N Schupf D Pang BN Patel, et al. 2003 Onset of dementia is associated with age at menopause in women with Down's syndrome Ann Neurol 54 433 438 10.1002/ana.10677 14520653
    • (2003) Ann Neurol , vol.54 , pp. 433-438
    • Schupf, N.1    Pang, D.2    Patel, B.N.3
  • 43
    • 1642512469 scopus 로고    scopus 로고
    • Elevated sex-hormone binding globulin in elderly women with Alzheimer's disease
    • 10.1016/S0197-4580(03)00046-0 1:CAS:528:DC%2BD2cXnvVKrtw%3D%3D 14749131
    • EK Hoskin MX Tang JJ Manly R Mayeux 2004 Elevated sex-hormone binding globulin in elderly women with Alzheimer's disease Neurobiol Aging 25 141 147 10.1016/S0197-4580(03)00046-0 1:CAS:528:DC%2BD2cXnvVKrtw%3D%3D 14749131
    • (2004) Neurobiol Aging , vol.25 , pp. 141-147
    • Hoskin, E.K.1    Tang, M.X.2    Manly, J.J.3    Mayeux, R.4
  • 44
    • 33748172357 scopus 로고    scopus 로고
    • Bioavailable estradiol and age at onset of Alzheimer's disease in postmenopausal women with Down syndrome
    • 10.1016/j.neulet.2006.07.062 1:CAS:528:DC%2BD28XpsVOmt70%3D 16926067
    • N Schupf S Winsten B Patel, et al. 2006 Bioavailable estradiol and age at onset of Alzheimer's disease in postmenopausal women with Down syndrome Neurosci Lett 406 298 302 10.1016/j.neulet.2006.07.062 1:CAS:528: DC%2BD28XpsVOmt70%3D 16926067
    • (2006) Neurosci Lett , vol.406 , pp. 298-302
    • Schupf, N.1    Winsten, S.2    Patel, B.3
  • 45
    • 0038077567 scopus 로고    scopus 로고
    • Endogenous estradiol and risk of dementia in women and men: The Rotterdam Study
    • 10.1002/ana.10521 1:CAS:528:DC%2BD3sXktVSntrk%3D 12730994
    • MI Geerlings LJ Launer FH de Jong, et al. 2003 Endogenous estradiol and risk of dementia in women and men: the Rotterdam Study Ann Neurol 53 607 615 10.1002/ana.10521 1:CAS:528:DC%2BD3sXktVSntrk%3D 12730994
    • (2003) Ann Neurol , vol.53 , pp. 607-615
    • Geerlings, M.I.1    Launer, L.J.2    De Jong, F.H.3
  • 46
    • 33845481822 scopus 로고    scopus 로고
    • Endogenous sex hormone levels and risk of cognitive decline in an older biracial cohort
    • 10.1016/j.neurobiolaging.2006.10.004 1:CAS:528:DC%2BD28XhtlaktL7F 17097195
    • K Yaffe D Barnes K Lindquist, et al. 2007 Endogenous sex hormone levels and risk of cognitive decline in an older biracial cohort Neurobiol Aging 28 171 178 10.1016/j.neurobiolaging.2006.10.004 1:CAS:528:DC%2BD28XhtlaktL7F 17097195
    • (2007) Neurobiol Aging , vol.28 , pp. 171-178
    • Yaffe, K.1    Barnes, D.2    Lindquist, K.3
  • 47
    • 0034021844 scopus 로고    scopus 로고
    • Higher levels of plasma estradiol and testosterone in healthy elderly men compared with age-matched women may protect aspects of explicit memory
    • 10.1097/00042192-200007030-00007 1:STN:280:DC%2BD3c3mvFSquw%3D%3D 10810962
    • LE Carlson BB Sherwin 2000 Higher levels of plasma estradiol and testosterone in healthy elderly men compared with age-matched women may protect aspects of explicit memory Menopause 7 168 177 10.1097/00042192-200007030-00007 1:STN:280:DC%2BD3c3mvFSquw%3D%3D 10810962
    • (2000) Menopause , vol.7 , pp. 168-177
    • Carlson, L.E.1    Sherwin, B.B.2
  • 48
    • 75149165139 scopus 로고    scopus 로고
    • Cognition is not modified by large but temporary changes in sex hormones in men
    • 10.1210/jc.2009-1346 1:CAS:528:DC%2BC3cXhtVGhsbs%3D 19880786
    • LA Young MB Neiss MH Samuels, et al. 2010 Cognition is not modified by large but temporary changes in sex hormones in men J Clin Endocrinol Metab 95 280 288 10.1210/jc.2009-1346 1:CAS:528:DC%2BC3cXhtVGhsbs%3D 19880786
    • (2010) J Clin Endocrinol Metab , vol.95 , pp. 280-288
    • Young, L.A.1    Neiss, M.B.2    Samuels, M.H.3
  • 49
    • 0030013029 scopus 로고    scopus 로고
    • Estradiol is related to visual memory in healthy young men
    • 10.1037/0735-7044.110.3.613 1:CAS:528:DyaK2sXmtVCqtbY%3D 8889006
    • DL Kampen BB Sherwin 1996 Estradiol is related to visual memory in healthy young men Behav Neurosci 110 613 617 10.1037/0735-7044.110.3.613 1:CAS:528:DyaK2sXmtVCqtbY%3D 8889006
    • (1996) Behav Neurosci , vol.110 , pp. 613-617
    • Kampen, D.L.1    Sherwin, B.B.2
  • 50
    • 0345708069 scopus 로고    scopus 로고
    • Serum levels of estradiol and testosterone and performance in different cognitive domains in healthy elderly men and women
    • 10.1016/S0306-4530(03)00053-2 1:CAS:528:DC%2BD3sXptlyhurw%3D 14644069
    • E Hogervorst C De Jager M Budge AD Smith 2004 Serum levels of estradiol and testosterone and performance in different cognitive domains in healthy elderly men and women Psychoneuroendocrinology 29 405 421 10.1016/S0306-4530(03) 00053-2 1:CAS:528:DC%2BD3sXptlyhurw%3D 14644069
    • (2004) Psychoneuroendocrinology , vol.29 , pp. 405-421
    • Hogervorst, E.1    De Jager, C.2    Budge, M.3    Smith, A.D.4
  • 51
    • 0036186427 scopus 로고    scopus 로고
    • Endogenous estradiol in elderly individuals: Cognitive and noncognitive associations
    • 10.1001/archneur.59.3.385 1:STN:280:DC%2BD387lvFCltQ%3D%3D 11890841
    • V Senanarong S Vannasaeng N Poungvarin, et al. 2002 Endogenous estradiol in elderly individuals: cognitive and noncognitive associations Arch Neurol 59 385 389 10.1001/archneur.59.3.385 1:STN:280:DC%2BD387lvFCltQ%3D%3D 11890841
    • (2002) Arch Neurol , vol.59 , pp. 385-389
    • Senanarong, V.1    Vannasaeng, S.2    Poungvarin, N.3
  • 52
    • 0036251660 scopus 로고    scopus 로고
    • Endogenous estradiol and testosterone levels are associated with cognitive performance in older women and men
    • 10.1006/hbeh.2002.1770 1:CAS:528:DC%2BD38XktVGhs7w%3D 11971659
    • OT Wolf C Kirschbaum 2002 Endogenous estradiol and testosterone levels are associated with cognitive performance in older women and men Horm Behav 41 259 266 10.1006/hbeh.2002.1770 1:CAS:528:DC%2BD38XktVGhs7w%3D 11971659
    • (2002) Horm Behav , vol.41 , pp. 259-266
    • Wolf, O.T.1    Kirschbaum, C.2
  • 53
    • 28044432960 scopus 로고    scopus 로고
    • Association of sex steroid hormones with brain morphology and cognition in healthy elderly men
    • 10.1212/01.wnl.0000184512.08249.48 1:CAS:528:DC%2BD2MXhtFOhsL%2FN 16301487
    • CN Lessov-Schlaggar T Reed GE Swan, et al. 2005 Association of sex steroid hormones with brain morphology and cognition in healthy elderly men Neurology 65 1591 1596 10.1212/01.wnl.0000184512.08249.48 1:CAS:528: DC%2BD2MXhtFOhsL%2FN 16301487
    • (2005) Neurology , vol.65 , pp. 1591-1596
    • Lessov-Schlaggar, C.N.1    Reed, T.2    Swan, G.E.3
  • 54
    • 73949083164 scopus 로고    scopus 로고
    • A randomized controlled trial of add-back estrogen or placebo on cognition in men with prostate cancer receiving an antiandrogen and a gonadotropin-releasing hormone analog
    • 10.1016/j.psyneuen.2009.06.012 1:CAS:528:DC%2BC3cXnt1Wrtw%3D%3D 19615826
    • RH Matousek BB Sherwin 2010 A randomized controlled trial of add-back estrogen or placebo on cognition in men with prostate cancer receiving an antiandrogen and a gonadotropin-releasing hormone analog Psychoneuroendocrinology 35 215 225 10.1016/j.psyneuen.2009.06.012 1:CAS:528:DC%2BC3cXnt1Wrtw%3D%3D 19615826
    • (2010) Psychoneuroendocrinology , vol.35 , pp. 215-225
    • Matousek, R.H.1    Sherwin, B.B.2
  • 55
    • 33749501951 scopus 로고    scopus 로고
    • Endogenous sex hormones, cognitive decline, and future dementia in old men
    • 10.1002/ana.20918 1:CAS:528:DC%2BD28XhtFyksLfJ 16865684
    • MI Geerlings D Strozyk K Masaki, et al. 2006 Endogenous sex hormones, cognitive decline, and future dementia in old men Ann Neurol 60 346 355 10.1002/ana.20918 1:CAS:528:DC%2BD28XhtFyksLfJ 16865684
    • (2006) Ann Neurol , vol.60 , pp. 346-355
    • Geerlings, M.I.1    Strozyk, D.2    Masaki, K.3
  • 56
    • 33845665357 scopus 로고    scopus 로고
    • Characterization of verbal and spatial memory changes from moderate to supraphysiological increases in serum testosterone in healthy older men
    • 10.1016/j.psyneuen.2006.10.008 1:CAS:528:DC%2BD2sXpvFGq 17145137
    • MM Cherrier AM Matsumoto JK Amory, et al. 2007 Characterization of verbal and spatial memory changes from moderate to supraphysiological increases in serum testosterone in healthy older men Psychoneuroendocrinology 32 72 79 10.1016/j.psyneuen.2006.10.008 1:CAS:528:DC%2BD2sXpvFGq 17145137
    • (2007) Psychoneuroendocrinology , vol.32 , pp. 72-79
    • Cherrier, M.M.1    Matsumoto, A.M.2    Amory, J.K.3
  • 57
    • 29144474501 scopus 로고    scopus 로고
    • Testosterone loss and estradiol administration modify memory in men
    • 10.1016/S0022-5347(05)00049-2 1:CAS:528:DC%2BD28XntlWktg%3D%3D 16406889
    • TM Beer LB Bland JR Bussiere, et al. 2006 Testosterone loss and estradiol administration modify memory in men J Urol 175 130 135 10.1016/S0022-5347(05) 00049-2 1:CAS:528:DC%2BD28XntlWktg%3D%3D 16406889
    • (2006) J Urol , vol.175 , pp. 130-135
    • Beer, T.M.1    Bland, L.B.2    Bussiere, J.R.3
  • 58
    • 0036235104 scopus 로고    scopus 로고
    • Effects of transdermal testosterone on cognitive function and health perception in older men with low bioavailable testosterone levels
    • 11983727
    • AM Kenny S Bellantonio CA Gruman, et al. 2002 Effects of transdermal testosterone on cognitive function and health perception in older men with low bioavailable testosterone levels J Gerontol A Biol Sci Med Sci 57 M321 M325 11983727
    • (2002) J Gerontol A Biol Sci Med Sci , vol.57
    • Kenny, A.M.1    Bellantonio, S.2    Gruman, C.A.3
  • 59
    • 1242352114 scopus 로고    scopus 로고
    • The effect of short-term estradiol therapy on cognitive function in older men receiving hormonal suppression therapy for prostate cancer
    • 10.1111/j.1532-5415.2004.52067.x 14728639
    • P Taxel MC Stevens M Trahiotis, et al. 2004 The effect of short-term estradiol therapy on cognitive function in older men receiving hormonal suppression therapy for prostate cancer J Am Geriatr Soc 52 269 273 10.1111/j.1532-5415.2004.52067.x 14728639
    • (2004) J Am Geriatr Soc , vol.52 , pp. 269-273
    • Taxel, P.1    Stevens, M.C.2    Trahiotis, M.3
  • 60
    • 0034123814 scopus 로고    scopus 로고
    • Sex steroids modify working memory
    • 10.1162/089892900562228 1:STN:280:DC%2BD3cvjsVKhtg%3D%3D 10931767
    • JS Janowsky B Chavez E Orwoll 2000 Sex steroids modify working memory J Cogn Neurosci 12 407 414 10.1162/089892900562228 1:STN:280: DC%2BD3cvjsVKhtg%3D%3D 10931767
    • (2000) J Cogn Neurosci , vol.12 , pp. 407-414
    • Janowsky, J.S.1    Chavez, B.2    Orwoll, E.3
  • 61
    • 12544249772 scopus 로고    scopus 로고
    • The role of aromatization in testosterone supplementation: Effects on cognition in older men
    • 10.1212/01.WNL.0000165995.98986.F1 1:CAS:528:DC%2BD2MXhvFOktw%3D%3D 15668427
    • MM Cherrier AM Matsumoto JK Amory, et al. 2005 The role of aromatization in testosterone supplementation: effects on cognition in older men Neurology 64 290 296 10.1212/01.WNL.0000165995.98986.F1 1:CAS:528:DC%2BD2MXhvFOktw%3D%3D 15668427
    • (2005) Neurology , vol.64 , pp. 290-296
    • Cherrier, M.M.1    Matsumoto, A.M.2    Amory, J.K.3
  • 62
    • 80051570913 scopus 로고    scopus 로고
    • A randomized controlled trial of estrogen treatment in men with mild cognitive impairment
    • Epub ahead of print
    • Sherwin BB, Chertkow H, Schipper H, Nasreddine Z: A randomized controlled trial of estrogen treatment in men with mild cognitive impairment. Neurobiol Aging (Epub ahead of print).
    • Neurobiol Aging
    • Sherwin, B.B.1    Chertkow, H.2    Schipper, H.3    Nasreddine, Z.4
  • 63
    • 0036218209 scopus 로고    scopus 로고
    • Sex hormones and cognitive function in older men
    • 10.1046/j.1532-5415.2002.50166.x 11982672
    • K Yaffe LY Lui J Zmuda J Cauley 2002 Sex hormones and cognitive function in older men J Am Geriatr Soc 50 707 712 10.1046/j.1532-5415.2002.50166.x 11982672
    • (2002) J Am Geriatr Soc , vol.50 , pp. 707-712
    • Yaffe, K.1    Lui, L.Y.2    Zmuda, J.3    Cauley, J.4
  • 64
    • 16844368852 scopus 로고    scopus 로고
    • Effect of raloxifene on prevention of dementia and cognitive impairment in older women: The Multiple Outcomes of Raloxifene Evaluation (MORE) randomized trial
    • 10.1176/appi.ajp.162.4.683 15800139
    • K Yaffe K Krueger SR Cummings, et al. 2005 Effect of raloxifene on prevention of dementia and cognitive impairment in older women: the Multiple Outcomes of Raloxifene Evaluation (MORE) randomized trial Am J Psychiatry 162 683 690 10.1176/appi.ajp.162.4.683 15800139
    • (2005) Am J Psychiatry , vol.162 , pp. 683-690
    • Yaffe, K.1    Krueger, K.2    Cummings, S.R.3
  • 65
    • 70449715476 scopus 로고    scopus 로고
    • Effects of tamoxifen and raloxifene on memory and other cognitive abilities: Cognition in the study of tamoxifen and raloxifene
    • 10.1200/JCO.2008.21.0716 1:CAS:528:DC%2BD1MXhsFahsLrP 19770382
    • C Legault PM Maki SM Resnick, et al. 2009 Effects of tamoxifen and raloxifene on memory and other cognitive abilities: cognition in the study of tamoxifen and raloxifene J Clin Oncol 27 5144 5152 10.1200/JCO.2008.21.0716 1:CAS:528:DC%2BD1MXhsFahsLrP 19770382
    • (2009) J Clin Oncol , vol.27 , pp. 5144-5152
    • Legault, C.1    Maki, P.M.2    Resnick, S.M.3
  • 66
    • 77950236952 scopus 로고    scopus 로고
    • Relative effects of tamoxifen, raloxifene, and conjugated equine estrogens on cognition
    • 10.1089/jwh.2009.1605
    • MA Espeland SA Shumaker M Limacher, et al. 2010 Relative effects of tamoxifen, raloxifene, and conjugated equine estrogens on cognition J Womens Health (Larchmt) 19 371 379 10.1089/jwh.2009.1605
    • (2010) J Womens Health (Larchmt) , vol.19 , pp. 371-379
    • Espeland, M.A.1    Shumaker, S.A.2    Limacher, M.3
  • 67
    • 0033585056 scopus 로고    scopus 로고
    • Association of the estrogen receptor alpha gene polymorphisms with sporadic Alzheimer's disease
    • 10.1006/bbrc.1999.1665 1:CAS:528:DyaK1MXnt1SlsrY%3D 10558867
    • ML Brandi L Becherini L Gennari, et al. 1999 Association of the estrogen receptor alpha gene polymorphisms with sporadic Alzheimer's disease Biochem Biophys Res Commun 265 335 338 10.1006/bbrc.1999.1665 1:CAS:528: DyaK1MXnt1SlsrY%3D 10558867
    • (1999) Biochem Biophys Res Commun , vol.265 , pp. 335-338
    • Brandi, M.L.1    Becherini, L.2    Gennari, L.3
  • 68
    • 33745210614 scopus 로고    scopus 로고
    • Association of estrogen receptor alpha (ESR1) PvuII and XbaI polymorphisms with sporadic Alzheimer's disease and their effect on apolipoprotein e concentrations
    • 10.1159/000093315 1:CAS:528:DC%2BD28XlvVemt7s%3D 16699281
    • RM Corbo G Gambina M Ruggeri R Scacchi 2006 Association of estrogen receptor alpha (ESR1) PvuII and XbaI polymorphisms with sporadic Alzheimer's disease and their effect on apolipoprotein E concentrations Dement Geriatr Cogn Disord 22 67 72 10.1159/000093315 1:CAS:528:DC%2BD28XlvVemt7s%3D 16699281
    • (2006) Dement Geriatr Cogn Disord , vol.22 , pp. 67-72
    • Corbo, R.M.1    Gambina, G.2    Ruggeri, M.3    Scacchi, R.4
  • 69
    • 0032802798 scopus 로고    scopus 로고
    • Positive association between an estrogen receptor gene polymorphism and Parkinson's disease with dementia
    • 10.1046/j.1468-1331.1999.640431.x 1:STN:280:DyaK1M3pt12rtA%3D%3D 10362895
    • K Isoe-Wada M Maeda J Yong, et al. 1999 Positive association between an estrogen receptor gene polymorphism and Parkinson's disease with dementia Eur J Neurol 6 431 435 10.1046/j.1468-1331.1999.640431.x 1:STN:280: DyaK1M3pt12rtA%3D%3D 10362895
    • (1999) Eur J Neurol , vol.6 , pp. 431-435
    • Isoe-Wada, K.1    Maeda, M.2    Yong, J.3
  • 70
    • 0033995124 scopus 로고    scopus 로고
    • Estrogen receptor gene polymorphisms in patients with Alzheimer's disease, vascular dementia and alcohol-associated dementia
    • 10.1159/000017224 1:CAS:528:DC%2BD3cXktVOmtLc%3D 10765041
    • Y Ji K Urakami K Wada-Isoe, et al. 2000 Estrogen receptor gene polymorphisms in patients with Alzheimer's disease, vascular dementia and alcohol-associated dementia Dement Geriatr Cogn Disord 11 119 122 10.1159/000017224 1:CAS:528:DC%2BD3cXktVOmtLc%3D 10765041
    • (2000) Dement Geriatr Cogn Disord , vol.11 , pp. 119-122
    • Ji, Y.1    Urakami, K.2    Wada-Isoe, K.3
  • 71
    • 43049141541 scopus 로고    scopus 로고
    • Estrogen receptor-alpha variants increase risk of Alzheimer's disease in women with Down syndrome
    • 10.1159/000126495 1:CAS:528:DC%2BD1cXltFOktLk%3D 18408366
    • N Schupf JH Lee M Wei, et al. 2008 Estrogen receptor-alpha variants increase risk of Alzheimer's disease in women with Down syndrome Dement Geriatr Cogn Disord 25 476 482 10.1159/000126495 1:CAS:528:DC%2BD1cXltFOktLk%3D 18408366
    • (2008) Dement Geriatr Cogn Disord , vol.25 , pp. 476-482
    • Schupf, N.1    Lee, J.H.2    Wei, M.3
  • 72
    • 27244443755 scopus 로고    scopus 로고
    • Estrogen receptor beta gene variants are associated with increased risk of Alzheimer's disease in women
    • 10.1038/sj.ejhg.5201447 1:CAS:528:DC%2BD2MXovVOiurw%3D 15944651
    • M Pirskanen M Hiltunen A Mannermaa, et al. 2005 Estrogen receptor beta gene variants are associated with increased risk of Alzheimer's disease in women Eur J Hum Genet 13 1000 1006 10.1038/sj.ejhg.5201447 1:CAS:528: DC%2BD2MXovVOiurw%3D 15944651
    • (2005) Eur J Hum Genet , vol.13 , pp. 1000-1006
    • Pirskanen, M.1    Hiltunen, M.2    Mannermaa, A.3
  • 73
    • 0034748991 scopus 로고    scopus 로고
    • Investigations of a CA repeat in the oestrogen receptor beta gene in patients with Alzheimer's disease
    • 10.1038/sj.ejhg.5200714 1:CAS:528:DC%2BD3MXpt1eitLs%3D 11781694
    • C Forsell E Enmark K Axelman, et al. 2001 Investigations of a CA repeat in the oestrogen receptor beta gene in patients with Alzheimer's disease Eur J Hum Genet 9 802 804 10.1038/sj.ejhg.5200714 1:CAS:528:DC%2BD3MXpt1eitLs%3D 11781694
    • (2001) Eur J Hum Genet , vol.9 , pp. 802-804
    • Forsell, C.1    Enmark, E.2    Axelman, K.3
  • 74
    • 61849088952 scopus 로고    scopus 로고
    • Estrogen receptor genotype and risk of cognitive impairment in elders: Findings from the Health ABC study
    • 10.1016/j.neurobiolaging.2007.08.003 1:CAS:528:DC%2BD1MXjtF2nsLo%3D 17889406
    • K Yaffe K Lindquist S Sen, et al. 2009 Estrogen receptor genotype and risk of cognitive impairment in elders: findings from the Health ABC study Neurobiol Aging 30 607 614 10.1016/j.neurobiolaging.2007.08.003 1:CAS:528:DC%2BD1MXjtF2nsLo%3D 17889406
    • (2009) Neurobiol Aging , vol.30 , pp. 607-614
    • Yaffe, K.1    Lindquist, K.2    Sen, S.3
  • 75
    • 34247094924 scopus 로고    scopus 로고
    • CYP19 haplotypes increase risk for Alzheimer's disease
    • 10.1136/jmg.2005.039461 1:STN:280:DC%2BD28vlvFOhsg%3D%3D 16882736
    • R Huang SE Poduslo 2006 CYP19 haplotypes increase risk for Alzheimer's disease J Med Genet 43 e42 10.1136/jmg.2005.039461 1:STN:280: DC%2BD28vlvFOhsg%3D%3D 16882736
    • (2006) J Med Genet , vol.43 , pp. 42
    • Huang, R.1    Poduslo, S.E.2
  • 76
    • 1842580609 scopus 로고    scopus 로고
    • Polymorphisms in the CYP19 gene confer increased risk for Alzheimer disease
    • 1:CAS:528:DC%2BD2cXktFGjtL0%3D 15079018
    • S Iivonen E Corder M Lehtovirta, et al. 2004 Polymorphisms in the CYP19 gene confer increased risk for Alzheimer disease Neurology 62 1170 1176 1:CAS:528:DC%2BD2cXktFGjtL0%3D 15079018
    • (2004) Neurology , vol.62 , pp. 1170-1176
    • Iivonen, S.1    Corder, E.2    Lehtovirta, M.3
  • 77
    • 72549092806 scopus 로고    scopus 로고
    • Association of the aromatase gene with Alzheimer's disease in women
    • 10.1016/j.neulet.2009.10.089 1:CAS:528:DC%2BD1MXhs1Wgt77N 19879925
    • HT Butler DR Warden E Hogervorst, et al. 2010 Association of the aromatase gene with Alzheimer's disease in women Neurosci Lett 468 202 206 10.1016/j.neulet.2009.10.089 1:CAS:528:DC%2BD1MXhs1Wgt77N 19879925
    • (2010) Neurosci Lett , vol.468 , pp. 202-206
    • Butler, H.T.1    Warden, D.R.2    Hogervorst, E.3
  • 78
    • 66149122258 scopus 로고    scopus 로고
    • Genetic variation of CYP19 (aromatase) gene influences age at onset of Alzheimer's disease in women
    • 10.1159/000221832 1:CAS:528:DC%2BD1MXovFWrurY%3D 19478482
    • RM Corbo G Gambina L Ulizzi, et al. 2009 Genetic variation of CYP19 (aromatase) gene influences age at onset of Alzheimer's disease in women Dement Geriatr Cogn Disord 27 513 518 10.1159/000221832 1:CAS:528:DC%2BD1MXovFWrurY%3D 19478482
    • (2009) Dement Geriatr Cogn Disord , vol.27 , pp. 513-518
    • Corbo, R.M.1    Gambina, G.2    Ulizzi, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.