Clinical implications of hedgehog signaling pathway inhibitors

Chinese Journal of Cancer

Volumn 30, Issue 1, 2011, Pages 13-26

  Liu, Hailan ^a   Gu, Dongsheng ^a   Xie, Jingwu ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Animal model; Cancer; Clinical trials; Hedgehog; PTCH1; Signal transduction; Smoothened

Indexed keywords

2 AMINOTHIAZOLE; 2 CHLORO N [4 CHLORO 3 (2 PYRIDINYL)PHENYL] 4 METHANESULFONYLBENZAMIDE; ANTINEOPLASTIC AGENT; BMS 833923; COLECALCIFEROL; COMPOUND 5; COMPOUND Z; CURCUMIN; CYCLOPAMINE; CYCLOPAMINE TARTRATE; EPIGALLOCATECHIN GALLATE; GANT 58,61; GENISTEIN; HPI 1234; IPI 926; ITRACONAZOLE; JERVINE; LDE 225; N (3 METHOXYBENZYL) 3,3 DIMETHYL N [1 (3,4 METHYLENEDIOXYBENZYL) 2 (1 PIPERAZINYLCARBONYL) 4 PYRROLIDINYL]BUTYRAMIDE; PROTEIN PATCHED 1; RESVERATROL; ROBOTNIKININ; SANT 1234; SMOOTHENED PROTEIN; SONIC HEDGEHOG PROTEIN; SONIC HEDGEHOG PROTEIN SIGNALING INHIBITOR; TAZAROTENE; UNCLASSIFIED DRUG; XL 139;

ANTINEOPLASTIC ACTIVITY; BASAL CELL CARCINOMA; BASAL CELL NEVUS SYNDROME; CANCER GROWTH; CANCER SUSCEPTIBILITY; CARCINOGENESIS; CLINICAL TRIAL (TOPIC); CONCENTRATION RESPONSE; DRUG EFFICACY; DRUG TARGETING; FEEDBACK SYSTEM; GENE MUTATION; GENETIC ASSOCIATION; HUMAN; MEDULLOBLASTOMA; METASTASIS; NONHUMAN; PANCREAS ADENOCARCINOMA; PROSTATE CANCER; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVIEW; RHABDOMYOSARCOMA; SIGNAL TRANSDUCTION; SOLID TUMOR;

EID: 79954486712     PISSN: 1000467X     EISSN: 1944446X     Source Type: Journal    
DOI: 10.5732/cjc.010.10540     Document Type: Review

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