Cilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved

Genes and Development

Volumn 23, Issue 16, 2009, Pages 1910-1928

  Chen, Miao Hsueh ^a   Wilson, Christopher W ^a   Li, Ya Jun ^a   Law, Kelvin King Lo ^b,c   Lu, Chi Sheng ^a   Gacayan, Rhodora ^a   Zhang, Xiaoyun ^b,c   Hui, Chi Chung ^b,c   Chuang, Pao Tien ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b HOSPITAL FOR SICK CHILDREN   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

Author keywords

Evolution; Gli; Hedgehog; Primary cilium; Signal transduction; Sufu

Indexed keywords

PROTEIN; PROTEIN PATCHED 1; SMOOTHENED PROTEIN; SONIC HEDGEHOG PROTEIN; SPOP PROTEIN; SUPPRESSOR OF FUSED PROTEIN; TRANSCRIPTION FACTOR GLI1; TRANSCRIPTION FACTOR GLI2; TRANSCRIPTION FACTOR GLI3; UNCLASSIFIED DRUG; AXIN PROTEIN; CELL SURFACE RECEPTOR; DROSOPHILA PROTEIN; G PROTEIN COUPLED RECEPTOR; GLI3 PROTEIN, MOUSE; KRUPPEL LIKE FACTOR; NERVE PROTEIN; NUCLEAR PROTEIN; PATCHED RECEPTORS; REPRESSOR PROTEIN; SMO PROTEIN, MOUSE; SMOOTHENED PROTEIN, DROSOPHILA; SPOP PROTEIN, MOUSE; SUFU PROTEIN, DROSOPHILA; SUFU PROTEIN, MOUSE; SUFU PROTEIN, ZEBRAFISH; ZEBRAFISH PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; EMBRYO; EUKARYOTIC FLAGELLUM; FLY; GENE ACTIVATION; GENE REPRESSION; GENE TRANSLOCATION; HUMAN; HUMAN CELL; MAMMAL CELL; MOLECULAR EVOLUTION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; SPECIES; ZEBRA FISH; ANIMAL; CELL LINE; DROSOPHILA; GENETICS; METABOLISM; PHYSIOLOGY; UPREGULATION;

DANIO RERIO; ERINACEIDAE; MAMMALIA;

ANIMALS; CELL LINE, TRANSFORMED; CILIA; DROSOPHILA; DROSOPHILA PROTEINS; EVOLUTION, MOLECULAR; HEDGEHOG PROTEINS; HUMANS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MICE; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; RECEPTORS, CELL SURFACE; RECEPTORS, G-PROTEIN-COUPLED; REPRESSOR PROTEINS; SIGNAL TRANSDUCTION; UP-REGULATION; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 69249245332     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.1794109     Document Type: Article

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