Expansion of Bcr-Abl-Positive Leukemic Stem Cells Is Dependent on Hedgehog Pathway Activation

Cancer Cell

Volumn 14, Issue 3, 2008, Pages 238-249

  Dierks, Christine ^a,b   Beigi, Ronak ^b   Guo, Gui Rong ^b   Zirlik, Katja ^a   Stegert, Mario R ^b   Manley, Paul ^c   Trussell, Christopher ^b   Schmitt Graeff, Annette ^a   Landwerlin, Klemens ^a   Veelken, Hendrik ^a   Warmuth, Markus ^b,d  

^a UNIVERSITY OF FREIBURG   (Germany)

^b Department of Medicinal Chemistry ^*  (United States)

^c NOVARTIS PHARMA AG   (Switzerland)

^d NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

CELLCYCLE; STEMCELL

Indexed keywords

BCR ABL PROTEIN; CYCLOPAMINE; FLUOROURACIL; IMATINIB; NILOTINIB; SMOOTHENED PROTEIN; SONIC HEDGEHOG PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CANCER CHEMOTHERAPY; CANCER RELAPSE; CELL CLONE; CHRONIC MYELOID LEUKEMIA; CONTROLLED STUDY; DRUG TARGETING; EMBRYO; HEMATOPOIESIS; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STEM CELL; UPREGULATION;

ERINACEIDAE;

EID: 50649118068     PISSN: 15356108     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ccr.2008.08.003     Document Type: Article

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