Activating Smoothened mutations in sporadic basal-cell carcinoma

Nature

Volumn 391, Issue 6662, 1998, Pages 90-92

  Xie, Jingwu ^a   Murone, Maximilien ^b   Luoh, Shiuh Ming ^b   Ryan, Anne ^b   Gu, Qimin ^b   Zhang, Chaohui ^b   Bonifas, Jeannette M ^a   Lam, Ching Wan ^c   Hynes, Mary ^b   Goddard, Audrey ^b   Rosenthal, Arnon ^b   Epstein Jr , Ervin H ^a   De Sauvage, Frederic J ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b GENENTECH INC   (United States)

^c CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

ONCOPROTEIN; SMOOTHENED ONCOPROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BASAL CELL CARCINOMA; HUMAN; HUMAN CELL; MISSENSE MUTATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTO ONCOGENE; TRANSGENIC MOUSE;

ADENOVIRUS E1A PROTEINS; ANIMALS; CARCINOMA, BASAL CELL; CELL LINE; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 7; HEDGEHOG PROTEINS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; MICE; MICE, TRANSGENIC; MUTATION; ONCOGENES; POLYMERASE CHAIN REACTION; PROTEIN CONFORMATION; PROTEINS; RATS; RECEPTORS, CELL SURFACE; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION; SKIN NEOPLASMS; TRANS-ACTIVATORS; TRANSFECTION;

ADENOVIRIDAE; ANIMALIA; ERINACEIDAE; MURINAE; MUS MUSCULUS;

EID: 0031913524     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/34201     Document Type: Article

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