-
1
-
-
0345059765
-
Hedgehog signalling in cancer formation and maintenance
-
Pasca di Magliano M, Hebrok M. Hedgehog signalling in cancer formation and maintenance. Nat Rev Cancer 2003;3:903-11.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 903-911
-
-
Pasca Di Magliano, M.1
Hebrok, M.2
-
2
-
-
0035902140
-
The hedgehog and Wnt signalling pathways in cancer
-
Taipale J, Beachy PA. The hedgehog and Wnt signalling pathways in cancer. Nature 2001;411:349-54.
-
(2001)
Nature
, vol.411
, pp. 349-354
-
-
Taipale, J.1
Beachy, P.A.2
-
3
-
-
0032126734
-
Transducing hedgehog: The story so far
-
Ingham PW. Transducing hedgehog: the story so far. EMBO J 1998;17:3505-11.
-
(1998)
EMBO J
, vol.17
, pp. 3505-3511
-
-
Ingham, P.W.1
-
4
-
-
15844386165
-
Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome
-
Hahn H, Wicking C, Zaphiropoulous PG, Gailani MR, Shanley S, Chidambaram A, Vorechovsky I, Holmberg E, Unden AB, Gillies S, Negus K, Smyth I, et al. Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome. Cell 1996;85:841-51.
-
(1996)
Cell
, vol.85
, pp. 841-851
-
-
Hahn, H.1
Wicking, C.2
Zaphiropoulous, P.G.3
Gailani, M.R.4
Shanley, S.5
Chidambaram, A.6
Vorechovsky, I.7
Holmberg, E.8
Unden, A.B.9
Gillies, S.10
Negus, K.11
Smyth, I.12
-
5
-
-
15844381336
-
Human homolog of patched, a candidate gene for the basal cell nevus syndrome
-
Johnson RL, Rothman AL, Xie J, Goodrich LV, Bare JW, Bonifas JM, Quinn AG, Myers RM, Cox DR, Epstein EH Jr, Scott MP. Human homolog of patched, a candidate gene for the basal cell nevus syndrome. Science 1996;272:1668-71.
-
(1996)
Science
, vol.272
, pp. 1668-1671
-
-
Johnson, R.L.1
Rothman, A.L.2
Xie, J.3
Goodrich, L.V.4
Bare, J.W.5
Bonifas, J.M.6
Quinn, A.G.7
Myers, R.M.8
Cox, D.R.9
Epstein Jr., E.H.10
Scott, M.P.11
-
6
-
-
15644373337
-
Mutations of the PATCHED gene in several types of sporadic extracutaneous tumors
-
Xie J, Johnson RL, Zhang X, Bare JW, Waldman FM, Cogen PH, Menon AG, Warren RS, Chen LC, Scott MP, Epstein EH Jr. Mutations of the PATCHED gene in several types of sporadic extracutaneous tumors. Cancer Res 1997;57:2369-72.
-
(1997)
Cancer Res
, vol.57
, pp. 2369-2372
-
-
Xie, J.1
Johnson, R.L.2
Zhang, X.3
Bare, J.W.4
Waldman, F.M.5
Cogen, P.H.6
Menon, A.G.7
Warren, R.S.8
Chen, L.C.9
Scott, M.P.10
Epstein Jr., E.H.11
-
7
-
-
0031036694
-
Sporadic medulloblastomas contain PTCH mutations
-
Raffel C, Jenkins RB, Frederick L, Hebrink D, Alderete B, Fults DW, James CD. Sporadic medulloblastomas contain PTCH mutations. Cancer Res 1997;57:842-5.
-
(1997)
Cancer Res
, vol.57
, pp. 842-845
-
-
Raffel, C.1
Jenkins, R.B.2
Frederick, L.3
Hebrink, D.4
Alderete, B.5
Fults, D.W.6
James, C.D.7
-
8
-
-
0031913524
-
Activating smoothened mutations in sporadic basal-cell carcinoma
-
Xie J, Murone M, Luoh SM, Ryan A, Gu Q, Zhang C, Bonifas JM, Lam CW, Hynes M, Goddard A, Rosenthal A, Epstein EH Jr, et al. Activating smoothened mutations in sporadic basal-cell carcinoma. Nature 1998;391:90-2.
-
(1998)
Nature
, vol.391
, pp. 90-92
-
-
Xie, J.1
Murone, M.2
Luoh, S.M.3
Ryan, A.4
Gu, Q.5
Zhang, C.6
Bonifas, J.M.7
Lam, C.W.8
Hynes, M.9
Goddard, A.10
Rosenthal, A.11
Epstein Jr., E.H.12
-
9
-
-
0036648241
-
Mutations in SUFU predispose to medulloblastoma
-
Taylor MD, Liu L, Raffel C, Hui CC, Mainprize TG, Zhang X, Agatep R, Chiappa S, Gao L, Lowrance A, Hao A, Goldstein AM, et al. Mutations in SUFU predispose to medulloblastoma. Nat Genet 2002;31:306-10.
-
(2002)
Nat Genet
, vol.31
, pp. 306-310
-
-
Taylor, M.D.1
Liu, L.2
Raffel, C.3
Hui, C.C.4
Mainprize, T.G.5
Zhang, X.6
Agatep, R.7
Chiappa, S.8
Gao, L.9
Lowrance, A.10
Hao, A.11
Goldstein, A.M.12
-
10
-
-
0242669237
-
Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer
-
Watkins DN, Berman DM, Burkholder SG, Wang B, Beachy PA, Baylin SB. Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer. Nature 2003;422:313-7.
-
(2003)
Nature
, vol.422
, pp. 313-317
-
-
Watkins, D.N.1
Berman, D.M.2
Burkholder, S.G.3
Wang, B.4
Beachy, P.A.5
Baylin, S.B.6
-
11
-
-
0242270878
-
Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis
-
Thayer SP, Di Magliano MP, Heiser PW, Nielsen CM, Roberts DJ, Lauwers GY, Qi YP, Gysin S, Fernandez-Del Castillo C, Yajnik V, Antoniu B, McMahon M, et al. Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis. Nature 2003;425:851-6.
-
(2003)
Nature
, vol.425
, pp. 851-856
-
-
Thayer, S.P.1
Di Magliano, M.P.2
Heiser, P.W.3
Nielsen, C.M.4
Roberts, D.J.5
Lauwers, G.Y.6
Qi, Y.P.7
Gysin, S.8
Fernandez-Del Castillo, C.9
Yajnik, V.10
Antoniu, B.11
McMahon, M.12
-
12
-
-
0242268525
-
Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours
-
Berman DM, Karhadkar SS, Maitra A, Montes De Oca R, Gerstenblith MR, Briggs K, Parker AR, Shimada Y, Eshleman JR, Watkins DN, Beachy PA. Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours. Nature 2003;425:846-51.
-
(2003)
Nature
, vol.425
, pp. 846-851
-
-
Berman, D.M.1
Karhadkar, S.S.2
Maitra, A.3
Montes De Oca, R.4
Gerstenblith, M.R.5
Briggs, K.6
Parker, A.R.7
Shimada, Y.8
Eshleman, J.R.9
Watkins, D.N.10
Beachy, P.A.11
-
13
-
-
13644261744
-
Activation of the hedgehog pathway in advanced prostate cancer
-
Sheng T, Li C-X, Zhang X, Chi S, He N, Chen K, McCormick F, Gatalica Z, Xie J. Activation of the hedgehog pathway in advanced prostate cancer. Mol Cancer 2004;3:29.
-
(2004)
Mol Cancer
, vol.3
, pp. 29
-
-
Sheng, T.1
Li, C.-X.2
Zhang, X.3
Chi, S.4
He, N.5
Chen, K.6
McCormick, F.7
Gatalica, Z.8
Xie, J.9
-
14
-
-
4344659678
-
Inhibition of prostate cancer proliferation by interference with SONIC HEDGE-HOG-GLI1 signaling
-
Sanchez P, Hernandez AM, Stecca B, Kahler AJ, DeGueme AM, Barrett A, Beyna M, Datta MW, Datta S, Ruiz i Altaba A. Inhibition of prostate cancer proliferation by interference with SONIC HEDGE-HOG-GLI1 signaling. Proc Natl Acad Sci USA 2004;101:12561-6.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 12561-12566
-
-
Sanchez, P.1
Hernandez, A.M.2
Stecca, B.3
Kahler, A.J.4
Degueme, A.M.5
Barrett, A.6
Beyna, M.7
Datta, M.W.8
Datta, S.9
Ruiz I Altaba, A.10
-
15
-
-
6044243650
-
Hedgehog signalling in prostate regeneration, neoplasia and metastasis
-
Karhadkar SS, Bova GS, Abdallah N, Dhara S, Gardner D, Maitra A, Isaacs JT, Berman DM, Beachy PA. Hedgehog signalling in prostate regeneration, neoplasia and metastasis. Nature 2004;431:707-12.
-
(2004)
Nature
, vol.431
, pp. 707-712
-
-
Karhadkar, S.S.1
Bova, G.S.2
Abdallah, N.3
Dhara, S.4
Gardner, D.5
Maitra, A.6
Isaacs, J.T.7
Berman, D.M.8
Beachy, P.A.9
-
16
-
-
0032843811
-
Estimates of the worldwide mortality from 25 cancers in 1990
-
Pisani P, Parkin DM, Bray F, Ferlay J. Estimates of the worldwide mortality from 25 cancers in 1990. Int J Cancer 1999;83:18-29.
-
(1999)
Int J Cancer
, vol.83
, pp. 18-29
-
-
Pisani, P.1
Parkin, D.M.2
Bray, F.3
Ferlay, J.4
-
17
-
-
4043129541
-
Pathology of upper gastrointestinal malignancies
-
Sarbia M, Becker KF, Hofler H. Pathology of upper gastrointestinal malignancies. Semin Oncol 2004;31:465-75.
-
(2004)
Semin Oncol
, vol.31
, pp. 465-475
-
-
Sarbia, M.1
Becker, K.F.2
Hofler, H.3
-
18
-
-
0030990735
-
Human patched (PTCH) mRNA is overexpressed consistently in tumor cells of both familial and sporadic basal cell carcinoma
-
Unden A, Zaphiropoulos PG, Toftgard R, Stahle-Backdahl M. Human patched (PTCH) mRNA is overexpressed consistently in tumor cells of both familial and sporadic basal cell carcinoma. Cancer Res 1997;57:2336-40.
-
(1997)
Cancer Res
, vol.57
, pp. 2336-2340
-
-
Unden, A.1
Zaphiropoulos, P.G.2
Toftgard, R.3
Stahle-Backdahl, M.4
-
19
-
-
1542427154
-
IFNalpha induces Fas expression and apoptosis in hedgehog pathway activated BCC cells through inhibiting Ras-Erk signaling
-
Li C, Chi S, He N, Zhang X, Guicherit O, Wagner R, Tyring S, Xie J. IFNalpha induces Fas expression and apoptosis in hedgehog pathway activated BCC cells through inhibiting Ras-Erk signaling. Oncogene 2004;23:1608-17.
-
(2004)
Oncogene
, vol.23
, pp. 1608-1617
-
-
Li, C.1
Chi, S.2
He, N.3
Zhang, X.4
Guicherit, O.5
Wagner, R.6
Tyring, S.7
Xie, J.8
-
20
-
-
5644264887
-
Inhibition of smoothened signaling prevents ultraviolet B-induced basal cell carcinomas through regulation of Fas expression and apoptosis
-
Athar M, Li C, Tang X, Chi S, Zhang X, Kim AL, Tyring SK, Kopelovich L, Hebert J, Epstein EH Jr, Bickers DR, Xie J. Inhibition of smoothened signaling prevents ultraviolet B-induced basal cell carcinomas through regulation of Fas expression and apoptosis. Cancer Res 2004;64:7545-52.
-
(2004)
Cancer Res
, vol.64
, pp. 7545-7552
-
-
Athar, M.1
Li, C.2
Tang, X.3
Chi, S.4
Zhang, X.5
Kim, A.L.6
Tyring, S.K.7
Kopelovich, L.8
Hebert, J.9
Epstein Jr., E.H.10
Bickers, D.R.11
Xie, J.12
-
21
-
-
0035979147
-
A role of PDGFRalpha in basal cell carcinoma proliferation
-
Xie J, Aszterbaum M, Zhang X, Bonifas JM, Zachary C, Epstein E, McCormick F. A role of PDGFRalpha in basal cell carcinoma proliferation. Proc Natl Acad Sci USA 2001;98:9255-9.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 9255-9259
-
-
Xie, J.1
Aszterbaum, M.2
Zhang, X.3
Bonifas, J.M.4
Zachary, C.5
Epstein, E.6
McCormick, F.7
-
22
-
-
0036839405
-
Sonic hedgehog expression correlates with fundic gland differentiation in the adult gastrointestinal tract
-
van den Brink GR, Hardwick JC, Nielsen C, Xu C, ten Kate FJ, Glickman J, van Deventer SJ, Roberts DJ, Peppelenbosch MP. Sonic hedgehog expression correlates with fundic gland differentiation in the adult gastrointestinal tract. Gut 2002;51:628-33.
-
(2002)
Gut
, vol.51
, pp. 628-633
-
-
Van Den Brink, G.R.1
Hardwick, J.C.2
Nielsen, C.3
Xu, C.4
Ten Kate, F.J.5
Glickman, J.6
Van Deventer, S.J.7
Roberts, D.J.8
Peppelenbosch, M.P.9
-
23
-
-
0042338649
-
Differences in the levels of Sonic hedgehog protein during early foregut development caused by exposure to adriamycin give clues to the role of the Shh gene in oesophageal atresia
-
Arsic D, Keenan J, Quan QB, Beasley S. Differences in the levels of Sonic hedgehog protein during early foregut development caused by exposure to adriamycin give clues to the role of the Shh gene in oesophageal atresia. Pediatr Surg Int 2003;19:463-6.
-
(2003)
Pediatr Surg Int
, vol.19
, pp. 463-466
-
-
Arsic, D.1
Keenan, J.2
Quan, Q.B.3
Beasley, S.4
-
24
-
-
0035576196
-
Comparative genomic hybridization of esophageal squamous cell carcinoma: Correlations between chromosomal aberrations and disease progression/prognosis
-
Yen CC, Chen YJ, Chen JT, Hsia JY, Chen PM, Liu JH, Fan FS, Chiou TJ, Wang WS, Lin CH. Comparative genomic hybridization of esophageal squamous cell carcinoma: correlations between chromosomal aberrations and disease progression/prognosis. Cancer 2001;92:2769-77.
-
(2001)
Cancer
, vol.92
, pp. 2769-2777
-
-
Yen, C.C.1
Chen, Y.J.2
Chen, J.T.3
Hsia, J.Y.4
Chen, P.M.5
Liu, J.H.6
Fan, F.S.7
Chiou, T.J.8
Wang, W.S.9
Lin, C.H.10
-
25
-
-
0033899382
-
Chromosomal imbalances in Barrett's adenocarcinoma and the metaplasia-dysplasia-carcinoma sequence
-
Walch AK, Zitzelsberger HF, Bruch J, Keller G, Angermeier D, Aubele MM, Mueller J, Stein H, Braselmann H, Siewert JR, Hofler H, Werner M. Chromosomal imbalances in Barrett's adenocarcinoma and the metaplasia-dysplasia-carcinoma sequence. Am J Pathol 2000;156:555-66.
-
(2000)
Am J Pathol
, vol.156
, pp. 555-566
-
-
Walch, A.K.1
Zitzelsberger, H.F.2
Bruch, J.3
Keller, G.4
Angermeier, D.5
Aubele, M.M.6
Mueller, J.7
Stein, H.8
Braselmann, H.9
Siewert, J.R.10
Hofler, H.11
Werner, M.12
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