Glypican-3 Inhibits Hedgehog Signaling during Development by Competing with Patched for Hedgehog Binding

Developmental Cell

Volumn 14, Issue 5, 2008, Pages 700-711

  Capurro, Mariana I ^a   Xu, Ping ^a   Shi, Wen ^a   Li, Fuchuan ^a   Jia, Angela ^a   Filmus, Jorge ^a  

^a Sunnybrook Health Sciences Centre   (Canada)

Author keywords

SIGNALING

Indexed keywords

GLYPICAN 3; HEPARAN SULFATE; PROTEIN PATCHED; SONIC HEDGEHOG PROTEIN;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ARTICLE; BINDING AFFINITY; CELL LINE; CONTROLLED STUDY; DEVELOPMENT; EMBRYO; ENDOCYTOSIS; FIBROBLAST; GENE MUTATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; INHIBITION KINETICS; MAMMAL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN INTERACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SIMPSON GOLABI BEHMEL SYNDROME; WESTERN BLOTTING;

ANIMALS; BINDING, COMPETITIVE; CELL LINE; EMBRYO, MAMMALIAN; ENDOCYTOSIS; FIBROBLASTS; GLYPICANS; HEDGEHOG PROTEINS; HUMANS; MICE; PROTEIN BINDING; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECEPTORS, CELL SURFACE; SIGNAL TRANSDUCTION;

ERINACEIDAE; MAMMALIA; MUS;

EID: 43049097898     PISSN: 15345807     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.devcel.2008.03.006     Document Type: Article

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