Loss of the retrograde motor for IFT disrupts localization of Smo to cilia and prevents the expression of both activator and repressor functions of Gli

Developmental Biology

Volumn 287, Issue 2, 2005, Pages 378-389

  May, Scott R ^a   Ashique, Amir M ^a   Karlen, Mattias ^c   Wang, Baolin ^d   Shen, Yiguo ^a   Zarbalis, Kostantinos ^a   Reiter, Jeremy ^e   Ericson, Johan ^c   Peterson, Andrew S ^a,b,f  

^a UNIVERSITY OF CALIFORNIA SAN FRANCISCO   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c KAROLINSKA INSTITUTE   (Sweden)

^d WEILL CORNELL MEDICAL COLLEGE   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f GENENTECH INC   (United States)

Author keywords

Gli cortical patterning; Primary cilia; Shh; Smoothened

Indexed keywords

ISOPROTEIN; PROTEIN; PROTEIN PATCHED; RAB PROTEIN; SMOOTHENED PROTEIN; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GLI3; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL ORGANELLE; CONTROLLED STUDY; EMBRYO; EUKARYOTIC FLAGELLUM; FUNCTIONAL PROTEOMICS; GENE; INTRAFLAGELLAR TRANSPORT GENE; MOLECULAR DYNAMICS; MOUSE; MUTANT; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROCESSING; REGULATORY MECHANISM; REPRESSOR GENE; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION;

ANIMALIA; ERINACEIDAE; EUKARYOTA;

EID: 27744484694     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ydbio.2005.08.050     Document Type: Article

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