Numb is a suppressor of Hedgehog signalling and targets Gli1 for Itch-dependent ubiquitination

Nature Cell Biology

Volumn 8, Issue 12, 2006, Pages 1415-1423

  Di Marcotullio, Lucia ^a   Ferretti, Elisabetta ^a   Greco, Azzura ^a   De Smaele, Enrico ^a   Po, Agnese ^a   Sico, Maria Anna ^a   Alimandi, Maurizio ^a   Giannini, Giuseppe ^a   Maroder, Marella ^a   Screpanti, Isabella ^a   Gulino, Alberto ^a,b  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b IRCCS NEUROMED   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ITCH PROTEIN; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GLI1; UBIQUITIN PROTEIN LIGASE E3;

ANIMAL CELL; ARTICLE; BRAIN CANCER; CANCER CELL CULTURE; CANCER INHIBITION; CARCINOGENESIS; CELL FATE; CELL PROLIFERATION; CELL RENEWAL; CONTROLLED STUDY; DOWN REGULATION; GRANULE CELL; HUMAN; HUMAN CELL; MORPHOGENESIS; MOUSE; NERVE CELL DIFFERENTIATION; NEURAL STEM CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN TARGETING; SIGNAL TRANSDUCTION; UBIQUITINATION;

ANIMALS; CEREBELLAR NEOPLASMS; CEREBELLUM; DOWN-REGULATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HEDGEHOG PROTEINS; HUMANS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MEDULLOBLASTOMA; MEMBRANE PROTEINS; MICE; NERVE TISSUE PROTEINS; PROTEIN PROCESSING, POST-TRANSLATIONAL; REPRESSOR PROTEINS; RNA, MESSENGER; SIGNAL TRANSDUCTION; STEM CELLS; TRANSCRIPTION FACTORS; UBIQUITIN-PROTEIN LIGASES; UBIQUITINS;

ERINACEIDAE;

EID: 33751503224     PISSN: 14657392     EISSN: None     Source Type: Journal    
DOI: 10.1038/ncb1510     Document Type: Article

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