메뉴 건너뛰기




Volumn 9, Issue 2, 2011, Pages 220-237

Seeking novel targets for improving In Vivo macrophage-specific reverse cholesterol transport: Translating basic science into new therapies for the prevention and treatment of atherosclerosis

Author keywords

Atherosclerosis; Cardiovascular disease; High density lipoprotein; Macrophages; Mice; Reverse cholesterol transport

Indexed keywords

[2 METHYL 4 [4 METHYL 2 (4 TRIFLUOROMETHYLPHENYL) 5 THIAZOLYLMETHYLTHIO]PHENOXY]ACETIC ACID; [4 [2 (3 FLUORO 4 TRIFLUOROMETHYLPHENYL) 4 METHYL 5 THIAZOLYLMETHYLTHIO] 2 METHYLPHENOXY]ACETIC ACID; ABC TRANSPORTER A1; ABC TRANSPORTER G5; ANACETRAPIB; APOLIPOPROTEIN A1; APOLIPOPROTEIN E; ATORVASTATIN; CHOLESTEROL ESTER TRANSFER PROTEIN; CHOLESTEROL ESTER TRANSFER PROTEIN INHIBITOR; CHOLESTEROL ESTERASE; DALCETRAPIB; ETC 216; EZETIMIBE; FENOFIBRATE; FERULIC ACID; FISH OIL; HIGH DENSITY LIPOPROTEIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LIVER X RECEPTOR AGONIST; MYCOPHENOLIC ACID; N (2,2,2 TRIFLUOROETHYL) N [4 [2,2,2 TRIFLUORO 1 HYDROXY 1 (TRIFLUOROMETHOXY)ETHYL]PHENYL]BENZENESULFONAMIDE; NEVIRAPINE; NONNUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONIST; PHOSPHATIDYLCHOLINE STEROL ACYLTRANSFERASE; PHOSPHOLIPID TRANSFER PROTEIN; SCAVENGER RECEPTOR BI; SIALOPROTEIN; TORCETRAPIB; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 79951719402     PISSN: 15701611     EISSN: None     Source Type: Journal    
DOI: 10.2174/157016111794519264     Document Type: Review
Times cited : (13)

References (303)
  • 1
    • 0016433018 scopus 로고
    • Plasma-high-density-lipoprotein concentration and development of ischaemic heart-disease
    • Miller GJ, Miller NE. Plasma-high-density-lipoprotein concentration and development of ischaemic heart-disease. Lancet 1975; 1:16-9.
    • (1975) Lancet , vol.1 , pp. 16-19
    • Miller, G.J.1    Miller, N.E.2
  • 2
    • 0024449985 scopus 로고
    • High-density lipoprotein--the clinical implications of recent studies
    • Gordon DJ, Rifkind BM. High-density lipoprotein--the clinical implications of recent studies. N Engl J Med 1989; 321: 1311-6.
    • (1989) N Engl J Med , vol.321 , pp. 1311-1316
    • Gordon, D.J.1    Rifkind, B.M.2
  • 3
    • 33845320131 scopus 로고    scopus 로고
    • Molecular regulation of HDL metabolism and function: Implications for novel therapies
    • Rader DJ. Molecular regulation of HDL metabolism and function: implications for novel therapies. J Clin Invest 2006; 116: 3090-100.
    • (2006) J Clin Invest , vol.116 , pp. 3090-3100
    • Rader, D.J.1
  • 4
    • 0019226419 scopus 로고
    • A-Imilano apoprotein. Isolation and characterization of a cysteine-containing variant of the A-I apoprotein from human high density lipoproteins
    • Weisgraber KH, Bersot TP, Mahley RW, et al. A-Imilano apoprotein. Isolation and characterization of a cysteine-containing variant of the A-I apoprotein from human high density lipoproteins. J Clin Invest 1980; 66: 901-7.
    • (1980) J Clin Invest , vol.66 , pp. 901-907
    • Weisgraber, K.H.1    Bersot, T.P.2    Mahley, R.W.3
  • 5
    • 0019226420 scopus 로고
    • A-IMilano apoprotein. Decreased high density lipoprotein cholesterol levels with significant lipoprotein modifications and without clinical atherosclerosis in an Italian family
    • Franceschini G, Sirtori CR, Capurso A 2nd, et al. A-IMilano apoprotein. Decreased high density lipoprotein cholesterol levels with significant lipoprotein modifications and without clinical atherosclerosis in an Italian family. J Clin Invest 1980; 66: 892-900.
    • (1980) J Clin Invest , vol.66 , pp. 892-900
    • Franceschini, G.1    Sirtori, C.R.2    Capurso II, A.3
  • 6
    • 0035901577 scopus 로고    scopus 로고
    • Cardiovascular status of carriers of the apolipoprotein A-I(Milano) mutant: The Limone sul Garda study
    • Sirtori CR, Calabresi L, Franceschini G, et al. Cardiovascular status of carriers of the apolipoprotein A-I(Milano) mutant: the Limone sul Garda study. Circulation 2001; 103: 1949-54.
    • (2001) Circulation , vol.103 , pp. 1949-1954
    • Sirtori, C.R.1    Calabresi, L.2    Franceschini, G.3
  • 7
    • 34047106220 scopus 로고    scopus 로고
    • Effect of torcetrapib on the progression of coronary atherosclerosis
    • Nissen SE, Tardif JC, Nicholls SJ, et al. Effect of torcetrapib on the progression of coronary atherosclerosis. N Engl J Med 2007; 356: 1304-16.
    • (2007) N Engl J Med , vol.356 , pp. 1304-1316
    • Nissen, S.E.1    Tardif, J.C.2    Nicholls, S.J.3
  • 8
    • 34247241088 scopus 로고    scopus 로고
    • Effect of torcetrapib on carotid atherosclerosis in familial hypercholesterolemia
    • Kastelein JJ, van Leuven SI, Burgess L, et al. Effect of torcetrapib on carotid atherosclerosis in familial hypercholesterolemia. N Engl J Med 2007; 356: 1620-30.
    • (2007) N Engl J Med , vol.356 , pp. 1620-1630
    • Kastelein, J.J.1    van Leuven, S.I.2    Burgess, L.3
  • 9
    • 34447265547 scopus 로고    scopus 로고
    • Torcetrapib and carotid intima-media thickness in mixed dyslipidaemia (RADIANCE 2 study): A randomised, double-blind trial
    • Bots ML, Visseren FL, Evans GW, et al. Torcetrapib and carotid intima-media thickness in mixed dyslipidaemia (RADIANCE 2 study): a randomised, double-blind trial. Lancet 2007; 370: 153-60.
    • (2007) Lancet , vol.370 , pp. 153-160
    • Bots, M.L.1    Visseren, F.L.2    Evans, G.W.3
  • 10
    • 36348975228 scopus 로고    scopus 로고
    • Effects of torcetrapib in patients at high risk for coronary events
    • Barter PJ, Caulfield M, Eriksson M, et al. Effects of torcetrapib in patients at high risk for coronary events. N Engl J Med 2007; 357: 2109-22.
    • (2007) N Engl J Med , vol.357 , pp. 2109-2122
    • Barter, P.J.1    Caulfield, M.2    Eriksson, M.3
  • 12
    • 0037058995 scopus 로고    scopus 로고
    • Disruption of Abcg5 and Abcg8 in mice reveals their crucial role in biliary cholesterol secretion
    • Yu L, Hammer RE, Li-Hawkins J, et al. Disruption of Abcg5 and Abcg8 in mice reveals their crucial role in biliary cholesterol secretion. Proc Natl Acad Sci USA 2002; 99: 16237-42.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 16237-16242
    • Yu, L.1    Hammer, R.E.2    Li-Hawkins, J.3
  • 13
    • 0035287440 scopus 로고    scopus 로고
    • Mouse models of hyperlipidemia and atherosclerosis
    • Fazio S, Linton MF. Mouse models of hyperlipidemia and atherosclerosis. Front Biosci 2001; 6: D515-25.
    • (2001) Front Biosci , vol.6
    • Fazio, S.1    Linton, M.F.2
  • 15
    • 0035082586 scopus 로고    scopus 로고
    • Mouse models of atherosclerosis
    • Reardon CA, Getz GS. Mouse models of atherosclerosis. Curr Opin Lipidol 2001; 12: 167-73.
    • (2001) Curr Opin Lipidol , vol.12 , pp. 167-173
    • Reardon, C.A.1    Getz, G.S.2
  • 16
    • 70349673274 scopus 로고    scopus 로고
    • HDL therapy for the treatment of cardiovascular diseases
    • Parolini C, Marchesi M, Chiesa G. HDL therapy for the treatment of cardiovascular diseases. Curr Vasc Pharmacol 2009; 7: 550-6.
    • (2009) Curr Vasc Pharmacol , vol.7 , pp. 550-556
    • Parolini, C.1    Marchesi, M.2    Chiesa, G.3
  • 17
    • 0029989281 scopus 로고    scopus 로고
    • Centripetal cholesterol flux from extrahepatic organs to the liver is independent of the concentration of high density lipoprotein-cholesterol in plasma
    • Osono Y, Woollett LA, Marotti KR, et al. Centripetal cholesterol flux from extrahepatic organs to the liver is independent of the concentration of high density lipoprotein-cholesterol in plasma. Proc Natl Acad Sci USA 1996; 93: 4114-9.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 4114-4119
    • Osono, Y.1    Woollett, L.A.2    Marotti, K.R.3
  • 18
    • 0031755081 scopus 로고    scopus 로고
    • Centripetal cholesterol flux to the liver is dictated by events in the peripheral organs and not by the plasma high density lipoprotein or apolipoprotein A-I concentration
    • Jolley CD, Woollett LA, Turley SD, Dietschy JM. Centripetal cholesterol flux to the liver is dictated by events in the peripheral organs and not by the plasma high density lipoprotein or apolipoprotein A-I concentration. J Lipid Res 1998; 39: 2143-9.
    • (1998) J Lipid Res , vol.39 , pp. 2143-2149
    • Jolley, C.D.1    Woollett, L.A.2    Turley, S.D.3    Dietschy, J.M.4
  • 19
    • 0035844301 scopus 로고    scopus 로고
    • Effect of up-regulating individual steps in the reverse cholesterol transport pathway on reverse cholesterol transport in normolipidemic mice
    • Alam K, Meidell RS, Spady DK. Effect of up-regulating individual steps in the reverse cholesterol transport pathway on reverse cholesterol transport in normolipidemic mice. J Biol Chem 2001; 276: 15641-9.
    • (2001) J Biol Chem , vol.276 , pp. 15641-15649
    • Alam, K.1    Meidell, R.S.2    Spady, D.K.3
  • 20
    • 0033652099 scopus 로고    scopus 로고
    • Induction of bile acid synthesis by cholesterol and cholestyramine feeding is unimpaired in mice deficient in apolipoprotein AI
    • Jolley CD, Dietschy JM, Turley SD. Induction of bile acid synthesis by cholesterol and cholestyramine feeding is unimpaired in mice deficient in apolipoprotein AI. Hepatology 2000; 32: 1309-16.
    • (2000) Hepatology , vol.32 , pp. 1309-1316
    • Jolley, C.D.1    Dietschy, J.M.2    Turley, S.D.3
  • 21
    • 0034823167 scopus 로고    scopus 로고
    • Hepatobiliary cholesterol transport is not impaired in Abca1-null mice lacking HDL
    • Groen AK, Bloks VW, Bandsma RH, et al. Hepatobiliary cholesterol transport is not impaired in Abca1-null mice lacking HDL. J Clin Invest 2001; 108: 843-50.
    • (2001) J Clin Invest , vol.108 , pp. 843-850
    • Groen, A.K.1    Bloks, V.W.2    Bandsma, R.H.3
  • 22
    • 44449103671 scopus 로고    scopus 로고
    • Beyond high-density lipoprotein cholesterol levels evaluating high-density lipoprotein function as influenced by novel therapeutic approaches
    • deGoma EM, deGoma RL, Rader DJ. Beyond high-density lipoprotein cholesterol levels evaluating high-density lipoprotein function as influenced by novel therapeutic approaches. J Am Coll Cardiol 2008; 51: 2199-211.
    • (2008) J Am Coll Cardiol , vol.51 , pp. 2199-2211
    • deGoma, E.M.1    deGoma, R.L.2    Rader, D.J.3
  • 23
    • 0037040184 scopus 로고    scopus 로고
    • Control of cholesterol turnover in the mouse
    • Dietschy JM, Turley SD. Control of cholesterol turnover in the mouse. J Biol Chem 2002; 277: 3801-4.
    • (2002) J Biol Chem , vol.277 , pp. 3801-3804
    • Dietschy, J.M.1    Turley, S.D.2
  • 24
    • 0033543084 scopus 로고    scopus 로고
    • Stimulation of fecal steroid excretion after infusion of recombinant proapolipoprotein A-I. Potential reverse cholesterol transport in humans
    • Eriksson M, Carlson LA, Miettinen TA, Angelin B. Stimulation of fecal steroid excretion after infusion of recombinant proapolipoprotein A-I. Potential reverse cholesterol transport in humans. Circulation 1999; 100: 594-8.
    • (1999) Circulation , vol.100 , pp. 594-598
    • Eriksson, M.1    Carlson, L.A.2    Miettinen, T.A.3    Angelin, B.4
  • 25
    • 0034763557 scopus 로고    scopus 로고
    • Intravenous apoA-I/lecithin discs increase pre-beta-HDL concentration in tissue fluid and stimulate reverse cholesterol transport in humans
    • Nanjee MN, Cooke CJ, Garvin R, et al. Intravenous apoA-I/lecithin discs increase pre-beta-HDL concentration in tissue fluid and stimulate reverse cholesterol transport in humans. J Lipid Res 2001; 42: 1586-93.
    • (2001) J Lipid Res , vol.42 , pp. 1586-1593
    • Nanjee, M.N.1    Cooke, C.J.2    Garvin, R.3
  • 26
    • 20944437770 scopus 로고    scopus 로고
    • Effects of cholesteryl ester transfer protein inhibition on high-density lipoprotein subspecies, apolipoprotein A-I metabolism, and fecal sterol excretion
    • Brousseau ME, Diffenderfer MR, Millar JS, et al. Effects of cholesteryl ester transfer protein inhibition on high-density lipoprotein subspecies, apolipoprotein A-I metabolism, and fecal sterol excretion. Arterioscler Thromb Vasc Biol 2005; 25: 1057-64.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 1057-1064
    • Brousseau, M.E.1    Diffenderfer, M.R.2    Millar, J.S.3
  • 27
    • 0041662117 scopus 로고    scopus 로고
    • Overexpression of apolipoprotein A-I promotes reverse transport of cholesterol from macrophages to feces in vivo
    • Zhang Y, Zanotti I, Reilly MP, et al. Overexpression of apolipoprotein A-I promotes reverse transport of cholesterol from macrophages to feces in vivo. Circulation 2003; 108: 661-3.
    • (2003) Circulation , vol.108 , pp. 661-663
    • Zhang, Y.1    Zanotti, I.2    Reilly, M.P.3
  • 28
    • 34547700634 scopus 로고    scopus 로고
    • Macrophage ABCA1 and ABCG1, but not SR-BI, promote macrophage reverse cholesterol transport in vivo
    • Wang X, Collins HL, Ranalletta M, et al. Macrophage ABCA1 and ABCG1, but not SR-BI, promote macrophage reverse cholesterol transport in vivo. J Clin Invest 2007; 117: 2216-24.
    • (2007) J Clin Invest , vol.117 , pp. 2216-2224
    • Wang, X.1    Collins, H.L.2    Ranalletta, M.3
  • 29
    • 66349086459 scopus 로고    scopus 로고
    • The role of reverse cholesterol transport in animals and humans and relationship to atherosclerosis
    • Rader DJ, Alexander ET, Weibel GL, et al. The role of reverse cholesterol transport in animals and humans and relationship to atherosclerosis. J Lipid Res 2009; 50(Suppl): S189-94.
    • (2009) J Lipid Res , vol.50 , Issue.SUPPL
    • Rader, D.J.1    Alexander, E.T.2    Weibel, G.L.3
  • 30
    • 70349434883 scopus 로고    scopus 로고
    • In vivo macrophage- specific RCT and antioxidant and antiinflammatory HDL activity measurements: New tools for predicting HDL atheroprotection
    • Escola-Gil JC, Rotllan N, Julve J, Blanco-Vaca F. In vivo macrophage- specific RCT and antioxidant and antiinflammatory HDL activity measurements: new tools for predicting HDL atheroprotection. Atherosclerosis 2009; 206: 321-7.
    • (2009) Atherosclerosis , vol.206 , pp. 321-327
    • Escola-Gil, J.C.1    Rotllan, N.2    Julve, J.3    Blanco-Vaca, F.4
  • 31
    • 0032813808 scopus 로고    scopus 로고
    • Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency
    • Brooks-Wilson A, Marcil M, Clee SM, et al. Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency. Nat Genet 1999; 22: 336-45.
    • (1999) Nat Genet , vol.22 , pp. 336-345
    • Brooks-Wilson, A.1    Marcil, M.2    Clee, S.M.3
  • 32
    • 0032813809 scopus 로고    scopus 로고
    • The gene encoding ATPbinding cassette transporter 1 is mutated in Tangier disease
    • Bodzioch M, Orso E, Klucken J, et al. The gene encoding ATPbinding cassette transporter 1 is mutated in Tangier disease. Nat Genet 1999; 22: 347-51.
    • (1999) Nat Genet , vol.22 , pp. 347-351
    • Bodzioch, M.1    Orso, E.2    Klucken, J.3
  • 33
    • 0032813660 scopus 로고    scopus 로고
    • Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1
    • Rust S, Rosier M, Funke H, et al. Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1. Nat Genet 1999; 22: 352-5.
    • (1999) Nat Genet , vol.22 , pp. 352-355
    • Rust, S.1    Rosier, M.2    Funke, H.3
  • 34
    • 33745132444 scopus 로고    scopus 로고
    • Macrophage reverse cholesterol transport: Key to the regression of atherosclerosis?
    • Cuchel M, Rader DJ. Macrophage reverse cholesterol transport: key to the regression of atherosclerosis? Circulation 2006; 113: 2548-55.
    • (2006) Circulation , vol.113 , pp. 2548-2555
    • Cuchel, M.1    Rader, D.J.2
  • 35
    • 31044446982 scopus 로고    scopus 로고
    • Direct evidence in vivo of impaired macrophage-specific reverse cholesterol transport in ATP-binding cassette transporter A1-deficient mice
    • Calpe-Berdiel L, Rotllan N, Palomer X, et al. Direct evidence in vivo of impaired macrophage-specific reverse cholesterol transport in ATP-binding cassette transporter A1-deficient mice. Biochim Biophys Acta 2005; 1738: 6-9.
    • (2005) Biochim Biophys Acta , vol.1738 , pp. 6-9
    • Calpe-Berdiel, L.1    Rotllan, N.2    Palomer, X.3
  • 36
    • 34547645177 scopus 로고    scopus 로고
    • In vivo reverse cholesterol transport from macrophages lacking ABCA1 expression is impaired
    • Wang MD, Franklin V, Marcel YL. In vivo reverse cholesterol transport from macrophages lacking ABCA1 expression is impaired. Arterioscler Thromb Vasc Biol 2007; 27: 1837-42.
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , pp. 1837-1842
    • Wang, M.D.1    Franklin, V.2    Marcel, Y.L.3
  • 37
    • 58149477561 scopus 로고    scopus 로고
    • Enhancing apolipoprotein A-I-dependent cholesterol efflux elevates cholesterol export from macrophages in vivo
    • Mukhamedova N, Escher G, D'Souza W, et al. Enhancing apolipoprotein A-I-dependent cholesterol efflux elevates cholesterol export from macrophages in vivo. J Lipid Res 2008; 49: 2312-22.
    • (2008) J Lipid Res , vol.49 , pp. 2312-2322
    • Mukhamedova, N.1    Escher, G.2    D'Souza, W.3
  • 38
    • 18344364090 scopus 로고    scopus 로고
    • Leukocyte ABCA1 controls susceptibility to atherosclerosis and macrophage recruitment into tissues
    • van Eck M, Bos IS, Kaminski WE, et al. Leukocyte ABCA1 controls susceptibility to atherosclerosis and macrophage recruitment into tissues. Proc Natl Acad Sci USA 2002; 99: 6298-303.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 6298-6303
    • van Eck, M.1    Bos, I.S.2    Kaminski, W.E.3
  • 39
    • 0036120566 scopus 로고    scopus 로고
    • Increased atherosclerosis in hyperlipidemic mice with inactivation of ABCA1 in macrophages
    • Aiello RJ, Brees D, Bourassa PA, et al. Increased atherosclerosis in hyperlipidemic mice with inactivation of ABCA1 in macrophages. Arterioscler Thromb Vasc Biol 2002; 22: 630-7.
    • (2002) Arterioscler Thromb Vasc Biol , vol.22 , pp. 630-637
    • Aiello, R.J.1    Brees, D.2    Bourassa, P.A.3
  • 40
    • 33646685651 scopus 로고    scopus 로고
    • Macrophage ATP-binding cassette transporter A1 overexpression inhibits atherosclerotic lesion progression in low-density lipoprotein receptor knockout mice
    • Van Eck M, Singaraja RR, Ye D, et al. Macrophage ATP-binding cassette transporter A1 overexpression inhibits atherosclerotic lesion progression in low-density lipoprotein receptor knockout mice. Arterioscler Thromb Vasc Biol 2006; 26: 929-34.
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , pp. 929-934
    • Van Eck, M.1    Singaraja, R.R.2    Ye, D.3
  • 41
    • 25444524077 scopus 로고    scopus 로고
    • Redistribution of macrophage cholesteryl ester hydrolase from cytoplasm to lipid droplets upon lipid loading
    • Zhao B, Fisher BJ, St Clair RW, et al. Redistribution of macrophage cholesteryl ester hydrolase from cytoplasm to lipid droplets upon lipid loading. J Lipid Res 2005; 46: 2114-21.
    • (2005) J Lipid Res , vol.46 , pp. 2114-2121
    • Zhao, B.1    Fisher, B.J.2    St Clair, R.W.3
  • 42
    • 34948878197 scopus 로고    scopus 로고
    • Macrophage-specific transgenic expression of cholesteryl ester hydrolase significantly reduces atherosclerosis and lesion necrosis in Ldlr mice
    • Zhao B, Song J, Chow WN, et al. Macrophage-specific transgenic expression of cholesteryl ester hydrolase significantly reduces atherosclerosis and lesion necrosis in Ldlr mice. J Clin Invest 2007; 117: 2983-92.
    • (2007) J Clin Invest , vol.117 , pp. 2983-2992
    • Zhao, B.1    Song, J.2    Chow, W.N.3
  • 44
    • 66349110576 scopus 로고    scopus 로고
    • Overexpression of human 15(S)-lipoxygenase-1 in RAW macrophages leads to increased cholesterol mobilization and reverse cholesterol transport
    • Weibel GL, Joshi MR, Alexander ET, et al. Overexpression of human 15(S)-lipoxygenase-1 in RAW macrophages leads to increased cholesterol mobilization and reverse cholesterol transport. Arterioscler Thromb Vasc Biol 2009; 29: 837-42.
    • (2009) Arterioscler Thromb Vasc Biol , vol.29 , pp. 837-842
    • Weibel, G.L.1    Joshi, M.R.2    Alexander, E.T.3
  • 46
    • 34447498570 scopus 로고    scopus 로고
    • Modification of HDL3 by mild oxidative stress increases ATP-binding cassette transporter 1- mediated cholesterol efflux
    • Pirillo A, Uboldi P, Pappalardo G, et al. Modification of HDL3 by mild oxidative stress increases ATP-binding cassette transporter 1- mediated cholesterol efflux. Cardiovasc Res 2007; 75: 566-74.
    • (2007) Cardiovasc Res , vol.75 , pp. 566-574
    • Pirillo, A.1    Uboldi, P.2    Pappalardo, G.3
  • 47
    • 0032752579 scopus 로고    scopus 로고
    • Disruption of the 12/15- lipoxygenase gene diminishes atherosclerosis in apo E-deficient mice
    • Cyrus T, Witztum JL, Rader DJ, et al. Disruption of the 12/15- lipoxygenase gene diminishes atherosclerosis in apo E-deficient mice. J Clin Invest 1999; 103: 1597-604.
    • (1999) J Clin Invest , vol.103 , pp. 1597-1604
    • Cyrus, T.1    Witztum, J.L.2    Rader, D.J.3
  • 48
    • 0035826892 scopus 로고    scopus 로고
    • Absence of 12/15-lipoxygenase expression decreases lipid peroxidation and atherogenesis in apolipoprotein e-deficient mice
    • Cyrus T, Pratico D, Zhao L, et al. Absence of 12/15-lipoxygenase expression decreases lipid peroxidation and atherogenesis in apolipoprotein e-deficient mice. Circulation 2001; 103: 2277-82.
    • (2001) Circulation , vol.103 , pp. 2277-2282
    • Cyrus, T.1    Pratico, D.2    Zhao, L.3
  • 49
    • 10744233434 scopus 로고    scopus 로고
    • 12/15-Lipoxygenase activity mediates inflammatory monocyte/endothelial interactions and atherosclerosis in vivo
    • Reilly KB, Srinivasan S, Hatley ME et al. 12/15-Lipoxygenase activity mediates inflammatory monocyte/endothelial interactions and atherosclerosis in vivo. J Biol Chem 2004; 279: 9440-50.
    • (2004) J Biol Chem , vol.279 , pp. 9440-9450
    • Reilly, K.B.1    Srinivasan, S.2    Hatley, M.E.3
  • 50
    • 54049137639 scopus 로고    scopus 로고
    • Atherosclerosis: Evidence for impairment of resolution of vascular inflammation governed by specific lipid mediators
    • Merched AJ, Ko K, Gotlinger KH, et al. Atherosclerosis: evidence for impairment of resolution of vascular inflammation governed by specific lipid mediators. FASEB J 2008; 22: 3595-606.
    • (2008) FASEB J , vol.22 , pp. 3595-3606
    • Merched, A.J.1    Ko, K.2    Gotlinger, K.H.3
  • 51
    • 0025902231 scopus 로고
    • Inhibition of early atherogenesis in transgenic mice by human apolipoprotein AI
    • Rubin EM, Krauss RM, Spangler EA, et al. Inhibition of early atherogenesis in transgenic mice by human apolipoprotein AI. Nature 1991; 353: 265-7.
    • (1991) Nature , vol.353 , pp. 265-267
    • Rubin, E.M.1    Krauss, R.M.2    Spangler, E.A.3
  • 52
    • 0028025262 scopus 로고
    • Human apolipoprotein A-I gene expression increases high density lipoprotein and suppresses atherosclerosis in the apolipoprotein E-deficient mouse
    • Plump AS, Scott CJ, Breslow JL. Human apolipoprotein A-I gene expression increases high density lipoprotein and suppresses atherosclerosis in the apolipoprotein E-deficient mouse. Proc Natl Acad Sci USA 1994; 91: 9607-11.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 9607-9611
    • Plump, A.S.1    Scott, C.J.2    Breslow, J.L.3
  • 53
    • 0028167663 scopus 로고
    • Apolipoprotein AI transgene corrects apolipoprotein E deficiency-induced atherosclerosis in mice
    • Paszty C, Maeda N, Verstuyft J, Rubin EM. Apolipoprotein AI transgene corrects apolipoprotein E deficiency-induced atherosclerosis in mice. J Clin Invest 1994; 94: 899-903.
    • (1994) J Clin Invest , vol.94 , pp. 899-903
    • Paszty, C.1    Maeda, N.2    Verstuyft, J.3    Rubin, E.M.4
  • 54
    • 9544221670 scopus 로고    scopus 로고
    • Inhibition of atherosclerosis development in cholesterol-fed human apolipoprotein A-Itransgenic rabbits
    • Duverger N, Kruth H, Emmanuel F, et al. Inhibition of atherosclerosis development in cholesterol-fed human apolipoprotein A-Itransgenic rabbits. Circulation 1996; 94: 713-7.
    • (1996) Circulation , vol.94 , pp. 713-717
    • Duverger, N.1    Kruth, H.2    Emmanuel, F.3
  • 55
    • 0033547789 scopus 로고    scopus 로고
    • Somatic gene transfer of human ApoA-I inhibits atherosclerosis progression in mouse models
    • Benoit P, Emmanuel F, Caillaud JM, et al. Somatic gene transfer of human ApoA-I inhibits atherosclerosis progression in mouse models. Circulation 1999; 99: 105-10.
    • (1999) Circulation , vol.99 , pp. 105-110
    • Benoit, P.1    Emmanuel, F.2    Caillaud, J.M.3
  • 56
    • 0032706442 scopus 로고    scopus 로고
    • Regression of atherosclerosis induced by liver-directed gene transfer of apolipoprotein A-I in mice
    • Tangirala RK, Tsukamoto K, Chun SH, et al. Regression of atherosclerosis induced by liver-directed gene transfer of apolipoprotein A-I in mice. Circulation 1999; 100: 1816-22.
    • (1999) Circulation , vol.100 , pp. 1816-1822
    • Tangirala, R.K.1    Tsukamoto, K.2    Chun, S.H.3
  • 57
    • 0038193486 scopus 로고    scopus 로고
    • The lipidation by hepatocytes of human apolipoprotein A-I occurs by both ABCA1- dependent and -independent pathways
    • Kiss RS, McManus DC, Franklin V, et al. The lipidation by hepatocytes of human apolipoprotein A-I occurs by both ABCA1- dependent and -independent pathways. J Biol Chem 2003; 278: 10119-27.
    • (2003) J Biol Chem , vol.278 , pp. 10119-10127
    • Kiss, R.S.1    McManus, D.C.2    Franklin, V.3
  • 58
    • 70349579203 scopus 로고    scopus 로고
    • Macrophage reverse cholesterol transport in mice expressing ApoA-I Milano
    • Alexander ET, Weibel GL, Joshi MR, et al. Macrophage reverse cholesterol transport in mice expressing ApoA-I Milano. Arterioscler Thromb Vasc Biol 2009; 29: 1496-501.
    • (2009) Arterioscler Thromb Vasc Biol , vol.29 , pp. 1496-1501
    • Alexander, E.T.1    Weibel, G.L.2    Joshi, M.R.3
  • 59
    • 26844431924 scopus 로고    scopus 로고
    • Increased atherosclerosis in mice lacking apolipoprotein A-I attributable to both impaired reverse cholesterol transport and increased inflammation
    • Moore RE, Navab M, Millar JS, et al. Increased atherosclerosis in mice lacking apolipoprotein A-I attributable to both impaired reverse cholesterol transport and increased inflammation. Circ Res 2005; 97: 763-71.
    • (2005) Circ Res , vol.97 , pp. 763-771
    • Moore, R.E.1    Navab, M.2    Millar, J.S.3
  • 61
    • 33748976880 scopus 로고    scopus 로고
    • Mast cell proteases: Physiological tools to study functional significance of high density lipoproteins in the initiation of reverse cholesterol transport
    • Lee-Rueckert M, Kovanen PT. Mast cell proteases: physiological tools to study functional significance of high density lipoproteins in the initiation of reverse cholesterol transport. Atherosclerosis 2006; 189: 8-18.
    • (2006) Atherosclerosis , vol.189 , pp. 8-18
    • Lee-Rueckert, M.1    Kovanen, P.T.2
  • 62
    • 33845665664 scopus 로고    scopus 로고
    • Haptoglobin genotype is a regulator of reverse cholesterol transport in diabetes in vitro and in vivo
    • Asleh R, Miller-Lotan R, Aviram M, et al. Haptoglobin genotype is a regulator of reverse cholesterol transport in diabetes in vitro and in vivo. Circ Res 2006; 99: 1419-25.
    • (2006) Circ Res , vol.99 , pp. 1419-1425
    • Asleh, R.1    Miller-Lotan, R.2    Aviram, M.3
  • 63
    • 68249147985 scopus 로고    scopus 로고
    • Receptor targeting of hemoglobin mediated by the haptoglobins: Roles beyond heme scavenging
    • Nielsen MJ, Moestrup SK. Receptor targeting of hemoglobin mediated by the haptoglobins: roles beyond heme scavenging. Blood 2009; 114: 764-71.
    • (2009) Blood , vol.114 , pp. 764-771
    • Nielsen, M.J.1    Moestrup, S.K.2
  • 64
    • 0034727060 scopus 로고    scopus 로고
    • Haptoglobin phenotype and vascular complications in patients with diabetes
    • Levy AP, Roguin A, Hochberg I, et al. Haptoglobin phenotype and vascular complications in patients with diabetes. N Engl J Med 2000; 343: 969-70.
    • (2000) N Engl J Med , vol.343 , pp. 969-970
    • Levy, A.P.1    Roguin, A.2    Hochberg, I.3
  • 65
    • 14844345323 scopus 로고    scopus 로고
    • Haptoglobin genotypeand diabetes-dependent differences in iron-mediated oxidative stress in vitro and in vivo
    • Asleh R, Guetta J, Kalet-Litman S, et al. Haptoglobin genotypeand diabetes-dependent differences in iron-mediated oxidative stress in vitro and in vivo. Circ Res 2005; 96: 435-41.
    • (2005) Circ Res , vol.96 , pp. 435-441
    • Asleh, R.1    Guetta, J.2    Kalet-Litman, S.3
  • 66
    • 33847671755 scopus 로고    scopus 로고
    • Haptoglobin genotype is a determinant of iron, lipid peroxidation, and macrophage accumulation in the atherosclerotic plaque
    • Levy AP, Levy JE, Kalet-Litman S, et al. Haptoglobin genotype is a determinant of iron, lipid peroxidation, and macrophage accumulation in the atherosclerotic plaque. Arterioscler Thromb Vasc Biol 2007; 27: 134-40.
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , pp. 134-140
    • Levy, A.P.1    Levy, J.E.2    Kalet-Litman, S.3
  • 67
    • 0026592806 scopus 로고
    • Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E
    • Zhang SH, Reddick RL, Piedrahita JA, Maeda N. Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E. Science 1992; 258: 468-71.
    • (1992) Science , vol.258 , pp. 468-471
    • Zhang, S.H.1    Reddick, R.L.2    Piedrahita, J.A.3    Maeda, N.4
  • 68
    • 0026725757 scopus 로고
    • Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells
    • Plump AS, Smith JD, Hayek T, et al. Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells. Cell 1992; 71: 343-53.
    • (1992) Cell , vol.71 , pp. 343-353
    • Plump, A.S.1    Smith, J.D.2    Hayek, T.3
  • 69
    • 0036208796 scopus 로고    scopus 로고
    • Altered activities of anti-atherogenic enzymes LCAT, paraoxonase, and plateletactivating factor acetylhydrolase in atherosclerosis-susceptible mice
    • Forte TM, Subbanagounder G, Berliner JA, et al. Altered activities of anti-atherogenic enzymes LCAT, paraoxonase, and plateletactivating factor acetylhydrolase in atherosclerosis-susceptible mice. J Lipid Res 2002; 43: 477-85.
    • (2002) J Lipid Res , vol.43 , pp. 477-485
    • Forte, T.M.1    Subbanagounder, G.2    Berliner, J.A.3
  • 70
    • 0036124456 scopus 로고    scopus 로고
    • Both apolipoprotein E and immune deficiency exacerbate neointimal hyperplasia after vascular injury in mice
    • Zhu B, Reardon CA, Getz GS, Hui DY. Both apolipoprotein E and immune deficiency exacerbate neointimal hyperplasia after vascular injury in mice. Arterioscler Thromb Vasc Biol 2002; 22: 450-5.
    • (2002) Arterioscler Thromb Vasc Biol , vol.22 , pp. 450-455
    • Zhu, B.1    Reardon, C.A.2    Getz, G.S.3    Hui, D.Y.4
  • 71
    • 0030945298 scopus 로고    scopus 로고
    • Increased atherosclerosis in mice reconstituted with apolipoprotein E null macrophages
    • Fazio S, Babaev VR, Murray AB, et al. Increased atherosclerosis in mice reconstituted with apolipoprotein E null macrophages. Proc Natl Acad Sci USA 1997; 94: 4647-52.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 4647-4652
    • Fazio, S.1    Babaev, V.R.2    Murray, A.B.3
  • 72
    • 0034181351 scopus 로고    scopus 로고
    • Accelerated atherosclerosis in C57Bl/6 mice transplanted with ApoE-deficient bone marrow
    • Van Eck M, Herijgers N, Vidgeon-Hart M, et al. Accelerated atherosclerosis in C57Bl/6 mice transplanted with ApoE-deficient bone marrow. Atherosclerosis 2000; 150: 71-80.
    • (2000) Atherosclerosis , vol.150 , pp. 71-80
    • Van Eck, M.1    Herijgers, N.2    Vidgeon-Hart, M.3
  • 73
    • 0036793431 scopus 로고    scopus 로고
    • Physiological expression of macrophage apoE in the artery wall reduces atherosclerosis in severely hyperlipidemic mice
    • Fazio S, Babaev VR, Burleigh ME, et al. Physiological expression of macrophage apoE in the artery wall reduces atherosclerosis in severely hyperlipidemic mice. J Lipid Res 2002; 43: 1602-9.
    • (2002) J Lipid Res , vol.43 , pp. 1602-1609
    • Fazio, S.1    Babaev, V.R.2    Burleigh, M.E.3
  • 74
    • 0035965336 scopus 로고    scopus 로고
    • Retrovirus-mediated expression of apolipoprotein A-I in the macrophage protects against atherosclerosis in vivo
    • Ishiguro H, Yoshida H, Major AS, et al. Retrovirus-mediated expression of apolipoprotein A-I in the macrophage protects against atherosclerosis in vivo. J Biol Chem 2001; 276: 36742-8.
    • (2001) J Biol Chem , vol.276 , pp. 36742-36748
    • Ishiguro, H.1    Yoshida, H.2    Major, A.S.3
  • 75
    • 0028883354 scopus 로고
    • Macrophage-specific expression of human apolipoprotein E reduces atherosclerosis in hypercholesterolemic apolipoprotein E-null mice
    • Bellosta S, Mahley RW, Sanan DA, et al. Macrophage-specific expression of human apolipoprotein E reduces atherosclerosis in hypercholesterolemic apolipoprotein E-null mice. J Clin Invest 1995; 96: 2170-9.
    • (1995) J Clin Invest , vol.96 , pp. 2170-2179
    • Bellosta, S.1    Mahley, R.W.2    Sanan, D.A.3
  • 76
    • 0028944150 scopus 로고
    • Prevention of atherosclerosis in apolipoprotein E-deficient mice by bone marrow transplantation
    • Linton MF, Atkinson JB, Fazio S. Prevention of atherosclerosis in apolipoprotein E-deficient mice by bone marrow transplantation. Science 1995; 267: 1034-7.
    • (1995) Science , vol.267 , pp. 1034-1037
    • Linton, M.F.1    Atkinson, J.B.2    Fazio, S.3
  • 77
    • 0033580593 scopus 로고    scopus 로고
    • Retroviral gene therapy in ApoE-deficient mice: ApoE expression in the artery wall reduces early foam cell lesion formation
    • Hasty AH, Linton MF, Brandt SJ, et al. Retroviral gene therapy in ApoE-deficient mice: ApoE expression in the artery wall reduces early foam cell lesion formation. Circulation 1999; 99: 2571-6.
    • (1999) Circulation , vol.99 , pp. 2571-2576
    • Hasty, A.H.1    Linton, M.F.2    Brandt, S.J.3
  • 78
    • 78650854310 scopus 로고    scopus 로고
    • Macrophage, but not systemic, apolipoprotein E is necessary for macrophage reverse cholesterol transport in vivo
    • Zanotti I, Pedrelli M, Potì F, et al. Macrophage, but not systemic, apolipoprotein E is necessary for macrophage reverse cholesterol transport in vivo. Arterioscler Thromb Vasc Biol 2011; 31: 74-80.
    • (2011) Arterioscler Thromb Vasc Biol , vol.31 , pp. 74-80
    • Zanotti, I.1    Pedrelli, M.2    Potì, F.3
  • 79
    • 0034060299 scopus 로고    scopus 로고
    • Gene transfer and hepatic overexpression of the HDL receptor SR-BI reduces atherosclerosis in the cholesterol-fed LDL receptor-deficient mouse
    • Kozarsky KF, Donahee MH, Glick JM, et al. Gene transfer and hepatic overexpression of the HDL receptor SR-BI reduces atherosclerosis in the cholesterol-fed LDL receptor-deficient mouse. Arterioscler Thromb Vasc Biol 2000; 20: 721-7.
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 721-727
    • Kozarsky, K.F.1    Donahee, M.H.2    Glick, J.M.3
  • 80
    • 0141988913 scopus 로고    scopus 로고
    • Influence of the HDL receptor SR-BI on lipoprotein metabolism and atherosclerosis
    • Trigatti BL, Krieger M, Rigotti A. Influence of the HDL receptor SR-BI on lipoprotein metabolism and atherosclerosis. Arterioscler Thromb Vasc Biol 2003; 23: 1732-8.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 1732-1738
    • Trigatti, B.L.1    Krieger, M.2    Rigotti, A.3
  • 81
    • 0033585115 scopus 로고    scopus 로고
    • Hepatic scavenger receptor BI promotes rapid clearance of high density lipoprotein free cholesterol and its transport into bile
    • Ji Y, Wang N, Ramakrishnan R, et al. Hepatic scavenger receptor BI promotes rapid clearance of high density lipoprotein free cholesterol and its transport into bile. J Biol Chem 1999; 274: 33398-402.
    • (1999) J Biol Chem , vol.274 , pp. 33398-33402
    • Ji, Y.1    Wang, N.2    Ramakrishnan, R.3
  • 82
    • 0042824072 scopus 로고    scopus 로고
    • Biliary lipid secretion, bile acid metabolism, and gallstone formation are not impaired in hepatic lipase-deficient mice
    • Amigo L, Mardones P, Ferrada C, et al. Biliary lipid secretion, bile acid metabolism, and gallstone formation are not impaired in hepatic lipase-deficient mice. Hepatology 2003; 38: 726-34.
    • (2003) Hepatology , vol.38 , pp. 726-734
    • Amigo, L.1    Mardones, P.2    Ferrada, C.3
  • 83
    • 0030960169 scopus 로고    scopus 로고
    • Overexpression of the HDL receptor SR-BI alters plasma HDL and bile cholesterol levels
    • Kozarsky KF, Donahee MH, Rigotti A, et al. Overexpression of the HDL receptor SR-BI alters plasma HDL and bile cholesterol levels. Nature 1997; 387: 414-7.
    • (1997) Nature , vol.387 , pp. 414-417
    • Kozarsky, K.F.1    Donahee, M.H.2    Rigotti, A.3
  • 84
    • 0032484117 scopus 로고    scopus 로고
    • Liver-specific overexpression of scavenger receptor BI decreases levels of very low density lipoprotein ApoB, low density lipoprotein ApoB, and high density lipoprotein in transgenic mice
    • Wang N, Arai T, Ji Y, et al. Liver-specific overexpression of scavenger receptor BI decreases levels of very low density lipoprotein ApoB, low density lipoprotein ApoB, and high density lipoprotein in transgenic mice. J Biol Chem 1998; 273: 32920-6.
    • (1998) J Biol Chem , vol.273 , pp. 32920-32926
    • Wang, N.1    Arai, T.2    Ji, Y.3
  • 85
    • 0030729724 scopus 로고    scopus 로고
    • A targeted mutation in the murine gene encoding the high density lipoprotein (HDL) receptor scavenger receptor class B type I reveals its key role in HDL metabolism
    • Rigotti A, Trigatti BL, Penman M, et al. A targeted mutation in the murine gene encoding the high density lipoprotein (HDL) receptor scavenger receptor class B type I reveals its key role in HDL metabolism. Proc Natl Acad Sci USA 1997; 94: 12610-5.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 12610-12615
    • Rigotti, A.1    Trigatti, B.L.2    Penman, M.3
  • 86
    • 13144275202 scopus 로고    scopus 로고
    • Targeted mutation reveals a central role for SR-BI in hepatic selective uptake of high density lipoprotein cholesterol
    • Varban ML, Rinninger F, Wang N, et al. Targeted mutation reveals a central role for SR-BI in hepatic selective uptake of high density lipoprotein cholesterol. Proc Natl Acad Sci USA 1998; 95: 4619-24.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 4619-4624
    • Varban, M.L.1    Rinninger, F.2    Wang, N.3
  • 87
    • 13044272898 scopus 로고    scopus 로고
    • Influence of the high density lipoprotein receptor SR-BI on reproductive and cardiovascular pathophysiology
    • Trigatti B, Rayburn H, Vinals M, et al. Influence of the high density lipoprotein receptor SR-BI on reproductive and cardiovascular pathophysiology. Proc Natl Acad Sci USA 1999; 96: 9322-7.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 9322-9327
    • Trigatti, B.1    Rayburn, H.2    Vinals, M.3
  • 88
    • 0033593222 scopus 로고    scopus 로고
    • Decreased atherosclerosis in heterozygous low density lipoprotein receptor-deficient mice expressing the scavenger receptor BI transgene
    • Arai T, Wang N, Bezouevski M, et al. Decreased atherosclerosis in heterozygous low density lipoprotein receptor-deficient mice expressing the scavenger receptor BI transgene. J Biol Chem 1999; 274: 2366-71.
    • (1999) J Biol Chem , vol.274 , pp. 2366-2371
    • Arai, T.1    Wang, N.2    Bezouevski, M.3
  • 89
    • 0034617069 scopus 로고    scopus 로고
    • Relationship between expression levels and atherogenesis in scavenger receptor class B, type I transgenics
    • Ueda Y, Gong E, Royer L, et al. Relationship between expression levels and atherogenesis in scavenger receptor class B, type I transgenics. J Biol Chem 2000; 275: 20368-73.
    • (2000) J Biol Chem , vol.275 , pp. 20368-20373
    • Ueda, Y.1    Gong, E.2    Royer, L.3
  • 90
    • 0037155049 scopus 로고    scopus 로고
    • Loss of SR-BI expression leads to the early onset of occlusive atherosclerotic coronary artery disease, spontaneous myocardial infarctions, severe cardiac dysfunction, and premature death in apolipoprotein E-deficient mice
    • Braun A, Trigatti BL, Post MJ, et al. Loss of SR-BI expression leads to the early onset of occlusive atherosclerotic coronary artery disease, spontaneous myocardial infarctions, severe cardiac dysfunction, and premature death in apolipoprotein E-deficient mice. Circ Res 2002; 90: 270-6.
    • (2002) Circ Res , vol.90 , pp. 270-276
    • Braun, A.1    Trigatti, B.L.2    Post, M.J.3
  • 91
    • 26444435788 scopus 로고    scopus 로고
    • Hepatic expression of scavenger receptor class B type I (SR-BI) is a positive regulator of macrophage reverse cholesterol transport in vivo
    • Zhang Y, Da Silva JR, Reilly M, et al. Hepatic expression of scavenger receptor class B type I (SR-BI) is a positive regulator of macrophage reverse cholesterol transport in vivo. J Clin Invest 2005; 115: 2870-4.
    • (2005) J Clin Invest , vol.115 , pp. 2870-2874
    • Zhang, Y.1    Da Silva, J.R.2    Reilly, M.3
  • 92
    • 33744979992 scopus 로고    scopus 로고
    • Human liver cholesteryl ester hydrolase: Cloning, molecular characterization, and role in cellular cholesterol homeostasis
    • Zhao B, Natarajan R, Ghosh S. Human liver cholesteryl ester hydrolase: cloning, molecular characterization, and role in cellular cholesterol homeostasis. Physiol Genomics 2005; 23: 304-10.
    • (2005) Physiol Genomics , vol.23 , pp. 304-310
    • Zhao, B.1    Natarajan, R.2    Ghosh, S.3
  • 93
    • 59849095754 scopus 로고    scopus 로고
    • Hepatic overexpression of cholesteryl ester hydrolase enhances cholesterol elimination and in vivo reverse cholesterol transport
    • Zhao B, Song J, Ghosh S. Hepatic overexpression of cholesteryl ester hydrolase enhances cholesterol elimination and in vivo reverse cholesterol transport. J Lipid Res 2008; 49: 2212-7.
    • (2008) J Lipid Res , vol.49 , pp. 2212-2217
    • Zhao, B.1    Song, J.2    Ghosh, S.3
  • 94
    • 0036733630 scopus 로고    scopus 로고
    • Overexpression of ABCG5 and ABCG8 promotes biliary cholesterol secretion and reduces fractional absorption of dietary cholesterol
    • Yu L, Li-Hawkins J, Hammer RE, et al. Overexpression of ABCG5 and ABCG8 promotes biliary cholesterol secretion and reduces fractional absorption of dietary cholesterol. J Clin Invest 2002; 110: 671-80.
    • (2002) J Clin Invest , vol.110 , pp. 671-680
    • Yu, L.1    Li-Hawkins, J.2    Hammer, R.E.3
  • 95
    • 33644865172 scopus 로고    scopus 로고
    • Pharmacological activation of liver X receptors promotes reverse cholesterol transport in vivo
    • Naik SU, Wang X, Da Silva JS, et al. Pharmacological activation of liver X receptors promotes reverse cholesterol transport in vivo. Circulation 2006; 113: 90-7.
    • (2006) Circulation , vol.113 , pp. 90-97
    • Naik, S.U.1    Wang, X.2    Da Silva, J.S.3
  • 96
    • 53149134712 scopus 로고    scopus 로고
    • Liver X receptormediated activation of reverse cholesterol transport from macrophages to feces in vivo requires ABCG5/G8
    • Calpe-Berdiel L, Rotllan N, Fievet C, et al. Liver X receptormediated activation of reverse cholesterol transport from macrophages to feces in vivo requires ABCG5/G8. J Lipid Res 2008; 49: 1904-11.
    • (2008) J Lipid Res , vol.49 , pp. 1904-1911
    • Calpe-Berdiel, L.1    Rotllan, N.2    Fievet, C.3
  • 97
    • 50049130053 scopus 로고    scopus 로고
    • The LXR agonist T0901317 promotes the reverse cholesterol transport from macrophages by increasing plasma efflux potential
    • Zanotti I, Poti F, Pedrelli M, et al. The LXR agonist T0901317 promotes the reverse cholesterol transport from macrophages by increasing plasma efflux potential. J Lipid Res 2008; 49: 954-60.
    • (2008) J Lipid Res , vol.49 , pp. 954-960
    • Zanotti, I.1    Poti, F.2    Pedrelli, M.3
  • 98
    • 77950605567 scopus 로고    scopus 로고
    • Liver X receptor activation promotes macrophage-to-feces reverse cholesterol transport in a dyslipidemic hamster model
    • Briand F, Treguier M, Andre A, et al. Liver X receptor activation promotes macrophage-to-feces reverse cholesterol transport in a dyslipidemic hamster model. J Lipid Res 2010; 51(4): 763-70.
    • (2010) J Lipid Res , vol.51 , Issue.4 , pp. 763-770
    • Briand, F.1    Treguier, M.2    Andre, A.3
  • 99
    • 70349563838 scopus 로고    scopus 로고
    • Both the peroxisome proliferatoractivated receptor d agonist, GW0742, and ezetimibe promote reverse cholesterol transport in mice by reducing intestinal reabsorption of HDL-derived cholesterol
    • Briand F, Fuki I, Millar JS, et al. Both the peroxisome proliferatoractivated receptor d agonist, GW0742, and ezetimibe promote reverse cholesterol transport in mice by reducing intestinal reabsorption of HDL-derived cholesterol. Clin Translat Sci 2009; 2: 127-33.
    • (2009) Clin Translat Sci , vol.2 , pp. 127-133
    • Briand, F.1    Fuki, I.2    Millar, J.S.3
  • 100
    • 70349565663 scopus 로고    scopus 로고
    • Fish oil promotes macrophage reverse cholesterol transport in mice
    • Nishimoto T, Pellizzon MA, Aihara M, et al. Fish oil promotes macrophage reverse cholesterol transport in mice. Arterioscler Thromb Vasc Biol 2009; 29: 1502-8.
    • (2009) Arterioscler Thromb Vasc Biol , vol.29 , pp. 1502-1508
    • Nishimoto, T.1    Pellizzon, M.A.2    Aihara, M.3
  • 101
    • 3442902180 scopus 로고    scopus 로고
    • High-level expression of ABCG5 and ABCG8 attenuates diet-induced hypercholesterolemia and atherosclerosis in Ldlr-/- mice
    • Wilund KR, Yu L, Xu F, et al. High-level expression of ABCG5 and ABCG8 attenuates diet-induced hypercholesterolemia and atherosclerosis in Ldlr-/- mice. J Lipid Res 2004; 45: 1429-36.
    • (2004) J Lipid Res , vol.45 , pp. 1429-1436
    • Wilund, K.R.1    Yu, L.2    Xu, F.3
  • 102
    • 10644258089 scopus 로고    scopus 로고
    • No association between plasma levels of plant sterols and atherosclerosis in mice and men
    • Wilund KR, Yu L, Xu F, et al. No association between plasma levels of plant sterols and atherosclerosis in mice and men. Arterioscler Thromb Vasc Biol 2004; 24: 2326-32.
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 2326-2332
    • Wilund, K.R.1    Yu, L.2    Xu, F.3
  • 103
    • 0038614979 scopus 로고    scopus 로고
    • Stimulation of cholesterol excretion by the liver X receptor agonist requires ATP-binding cassette transporters G5 and G8
    • Yu L, York J, von Bergmann K, et al. Stimulation of cholesterol excretion by the liver X receptor agonist requires ATP-binding cassette transporters G5 and G8. J Biol Chem 2003; 278: 15565-70.
    • (2003) J Biol Chem , vol.278 , pp. 15565-15570
    • Yu, L.1    York, J.2    von Bergmann, K.3
  • 104
    • 35248850233 scopus 로고    scopus 로고
    • Are LXRregulated genes a major molecular target of plant sterols/stanols?
    • Calpe-Berdiel L, Escola-Gil JC, Blanco-Vaca F. Are LXRregulated genes a major molecular target of plant sterols/stanols? Atherosclerosis 2007; 195: 210-1.
    • (2007) Atherosclerosis , vol.195 , pp. 210-211
    • Calpe-Berdiel, L.1    Escola-Gil, J.C.2    Blanco-Vaca, F.3
  • 105
    • 33845993219 scopus 로고    scopus 로고
    • Hepatic ABCG5/G8 overexpression reduces apoB-lipoproteins and atherosclerosis when cholesterol absorption is inhibited
    • Basso F, Freeman LA, Ko C, et al. Hepatic ABCG5/G8 overexpression reduces apoB-lipoproteins and atherosclerosis when cholesterol absorption is inhibited. J Lipid Res 2007; 48: 114-26.
    • (2007) J Lipid Res , vol.48 , pp. 114-126
    • Basso, F.1    Freeman, L.A.2    Ko, C.3
  • 107
    • 33947119204 scopus 로고    scopus 로고
    • Different cellular traffic of LDL-cholesterol and acetylated LDL-cholesterol leads to distinct reverse cholesterol transport pathways
    • Wang MD, Kiss RS, Franklin V, et al. Different cellular traffic of LDL-cholesterol and acetylated LDL-cholesterol leads to distinct reverse cholesterol transport pathways. J Lipid Res 2007; 48: 633-45.
    • (2007) J Lipid Res , vol.48 , pp. 633-645
    • Wang, M.D.1    Kiss, R.S.2    Franklin, V.3
  • 108
    • 37849039816 scopus 로고    scopus 로고
    • Coexistence of foam cells and hypocholesterolemia in mice lacking the ABC transporters A1 and G1
    • Out R, Jessup W, Le Goff W, et al. Coexistence of foam cells and hypocholesterolemia in mice lacking the ABC transporters A1 and G1. Circ Res 2008; 102: 113-20.
    • (2008) Circ Res , vol.102 , pp. 113-120
    • Out, R.1    Jessup, W.2    Le Goff, W.3
  • 109
    • 33749063446 scopus 로고    scopus 로고
    • Macrophage ABCG1 deletion disrupts lipid homeostasis in alveolar macrophages and moderately influences atherosclerotic lesion development in LDL receptor-deficient mice
    • Out R, Hoekstra M, Hildebrand RB, et al. Macrophage ABCG1 deletion disrupts lipid homeostasis in alveolar macrophages and moderately influences atherosclerotic lesion development in LDL receptor-deficient mice. Arterioscler Thromb Vasc Biol 2006; 26: 2295-300.
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , pp. 2295-2300
    • Out, R.1    Hoekstra, M.2    Hildebrand, R.B.3
  • 110
    • 33749064634 scopus 로고    scopus 로고
    • Decreased atherosclerosis in low-density lipoprotein receptor knockout mice transplanted with Abcg1-/- bone marrow
    • Ranalletta M, Wang N, Han S, et al. Decreased atherosclerosis in low-density lipoprotein receptor knockout mice transplanted with Abcg1-/- bone marrow. Arterioscler Thromb Vasc Biol 2006; 26: 2308-15.
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , pp. 2308-2315
    • Ranalletta, M.1    Wang, N.2    Han, S.3
  • 111
    • 33749060469 scopus 로고    scopus 로고
    • Impaired development of atherosclerosis in hyperlipidemic Ldlr-/- and ApoE-/- mice transplanted with Abcg1-/- bone marrow
    • Baldan A, Pei L, Lee R, et al. Impaired development of atherosclerosis in hyperlipidemic Ldlr-/- and ApoE-/- mice transplanted with Abcg1-/- bone marrow. Arterioscler Thromb Vasc Biol 2006; 26: 2301-7.
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , pp. 2301-2307
    • Baldan, A.1    Pei, L.2    Lee, R.3
  • 112
    • 36849011221 scopus 로고    scopus 로고
    • Combined deficiency of ABCA1 and ABCG1 promotes foam cell accumulation and accelerates atherosclerosis in mice
    • Yvan-Charvet L, Ranalletta M, Wang N, et al. Combined deficiency of ABCA1 and ABCG1 promotes foam cell accumulation and accelerates atherosclerosis in mice. J Clin Invest 2007; 117: 3900-8.
    • (2007) J Clin Invest , vol.117 , pp. 3900-3908
    • Yvan-Charvet, L.1    Ranalletta, M.2    Wang, N.3
  • 113
    • 38549139265 scopus 로고    scopus 로고
    • Combined deletion of macrophage ABCA1 and ABCG1 leads to massive lipid accumulation in tissue macrophages and distinct atherosclerosis at relatively low plasma cholesterol levels
    • Out R, Hoekstra M, Habets K, et al. Combined deletion of macrophage ABCA1 and ABCG1 leads to massive lipid accumulation in tissue macrophages and distinct atherosclerosis at relatively low plasma cholesterol levels. Arterioscler Thromb Vasc Biol 2008; 28: 258-64.
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , pp. 258-264
    • Out, R.1    Hoekstra, M.2    Habets, K.3
  • 114
    • 33749043006 scopus 로고    scopus 로고
    • Regulation of cholesterol homeostasis in macrophages and consequences for atherosclerotic lesion development
    • Pennings M, Meurs I, Ye D, et al. Regulation of cholesterol homeostasis in macrophages and consequences for atherosclerotic lesion development. FEBS Lett 2006; 580: 5588-96.
    • (2006) FEBS Lett , vol.580 , pp. 5588-5596
    • Pennings, M.1    Meurs, I.2    Ye, D.3
  • 115
    • 0041527450 scopus 로고    scopus 로고
    • Scavenger receptor class B type I-mediated protection against atherosclerosis in LDL receptornegative mice involves its expression in bone marrow-derived cells
    • Covey SD, Krieger M, Wang W, et al. Scavenger receptor class B type I-mediated protection against atherosclerosis in LDL receptornegative mice involves its expression in bone marrow-derived cells. Arterioscler Thromb Vasc Biol 2003; 23: 1589-94.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 1589-1594
    • Covey, S.D.1    Krieger, M.2    Wang, W.3
  • 116
    • 4344574038 scopus 로고    scopus 로고
    • Dual role for scavenger receptor class B, type I on bone marrow-derived cells in atherosclerotic lesion development
    • Van Eck M, Bos IS, Hildebrand RB, et al. Dual role for scavenger receptor class B, type I on bone marrow-derived cells in atherosclerotic lesion development. Am J Pathol 2004; 165: 785-94.
    • (2004) Am J Pathol , vol.165 , pp. 785-794
    • Van Eck, M.1    Bos, I.S.2    Hildebrand, R.B.3
  • 117
    • 0242266978 scopus 로고    scopus 로고
    • Inactivation of macrophage scavenger receptor class B type I promotes atherosclerotic lesion development in apolipoprotein E-deficient mice
    • Zhang W, Yancey PG, Su YR, et al. Inactivation of macrophage scavenger receptor class B type I promotes atherosclerotic lesion development in apolipoprotein E-deficient mice. Circulation 2003; 108: 2258-63.
    • (2003) Circulation , vol.108 , pp. 2258-2263
    • Zhang, W.1    Yancey, P.G.2    Su, Y.R.3
  • 118
    • 33749430965 scopus 로고    scopus 로고
    • Knockdown expression and hepatic deficiency reveal an atheroprotective role for SR-BI in liver and peripheral tissues
    • Huby T, Doucet C, Dachet C, et al. Knockdown expression and hepatic deficiency reveal an atheroprotective role for SR-BI in liver and peripheral tissues. J Clin Invest 2006; 116: 2767-76.
    • (2006) J Clin Invest , vol.116 , pp. 2767-2776
    • Huby, T.1    Doucet, C.2    Dachet, C.3
  • 119
    • 0034613336 scopus 로고    scopus 로고
    • Scavenger receptor-BI inhibits ATP-binding cassette transporter 1- mediated cholesterol efflux in macrophages
    • Chen W, Silver DL, Smith JD, Tall AR. Scavenger receptor-BI inhibits ATP-binding cassette transporter 1- mediated cholesterol efflux in macrophages. J Biol Chem 2000; 275: 30794-800.
    • (2000) J Biol Chem , vol.275 , pp. 30794-30800
    • Chen, W.1    Silver, D.L.2    Smith, J.D.3    Tall, A.R.4
  • 120
    • 0036205355 scopus 로고    scopus 로고
    • ApoE-dependent sterol efflux from macrophages is modulated by scavenger receptor class B type I expression
    • Huang ZH, Mazzone T. ApoE-dependent sterol efflux from macrophages is modulated by scavenger receptor class B type I expression. J Lipid Res 2002; 43: 375-82.
    • (2002) J Lipid Res , vol.43 , pp. 375-382
    • Huang, Z.H.1    Mazzone, T.2
  • 121
    • 36048956329 scopus 로고    scopus 로고
    • Increased oxidative stress in scavenger receptor BI knockout mice with dysfunctional HDL
    • Van Eck M, Hoekstra M, Hildebrand RB, et al. Increased oxidative stress in scavenger receptor BI knockout mice with dysfunctional HDL. Arterioscler Thromb Vasc Biol 2007; 27: 2413-9.
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , pp. 2413-2419
    • Van Eck, M.1    Hoekstra, M.2    Hildebrand, R.B.3
  • 122
    • 0035195675 scopus 로고    scopus 로고
    • Role of apoA-II in lipid metabolism and atherosclerosis: Advances in the study of an enigmatic protein
    • Blanco-Vaca F, Escola-Gil JC, Martin-Campos JM, Julve J. Role of apoA-II in lipid metabolism and atherosclerosis: advances in the study of an enigmatic protein. J Lipid Res 2001; 42: 1727-39.
    • (2001) J Lipid Res , vol.42 , pp. 1727-1739
    • Blanco-Vaca, F.1    Escola-Gil, J.C.2    Martin-Campos, J.M.3    Julve, J.4
  • 124
    • 0037399153 scopus 로고    scopus 로고
    • Apolipoprotein A-II: Beyond genetic associations with lipid disorders and insulin resistance
    • Kalopissis AD, Pastier D, Chambaz J. Apolipoprotein A-II: beyond genetic associations with lipid disorders and insulin resistance. Curr Opin Lipidol 2003; 14: 165-72.
    • (2003) Curr Opin Lipidol , vol.14 , pp. 165-172
    • Kalopissis, A.D.1    Pastier, D.2    Chambaz, J.3
  • 125
    • 2642545150 scopus 로고    scopus 로고
    • Apolipoprotein A-II, genetic variation on chromosome 1q21-q24, and disease susceptibility
    • Martin-Campos JM, Escola-Gil JC, Ribas V, Blanco-Vaca F. Apolipoprotein A-II, genetic variation on chromosome 1q21-q24, and disease susceptibility. Curr Opin Lipidol 2004; 15: 247-53.
    • (2004) Curr Opin Lipidol , vol.15 , pp. 247-253
    • Martin-Campos, J.M.1    Escola-Gil, J.C.2    Ribas, V.3    Blanco-Vaca, F.4
  • 126
    • 0031936294 scopus 로고    scopus 로고
    • Human apolipoprotein A-II is a pro-atherogenic molecule when it is expressed in transgenic mice at a level similar to that in humans: Evidence of a potentially relevant species-specific interaction with diet
    • Escola-Gil JC, Marzal-Casacuberta A, Julve-Gil J, et al. Human apolipoprotein A-II is a pro-atherogenic molecule when it is expressed in transgenic mice at a level similar to that in humans: evidence of a potentially relevant species-specific interaction with diet. J Lipid Res 1998; 39: 457-62.
    • (1998) J Lipid Res , vol.39 , pp. 457-462
    • Escola-Gil, J.C.1    Marzal-Casacuberta, A.2    Julve-Gil, J.3
  • 127
    • 0035091953 scopus 로고    scopus 로고
    • ApoA-II expression in CETP transgenic mice increases VLDL production and impairs VLDL clearance
    • Escola-Gil JC, Julve J, Marzal-Casacuberta A, et al. ApoA-II expression in CETP transgenic mice increases VLDL production and impairs VLDL clearance. J Lipid Res 2001; 42: 241-8.
    • (2001) J Lipid Res , vol.42 , pp. 241-248
    • Escola-Gil, J.C.1    Julve, J.2    Marzal-Casacuberta, A.3
  • 128
    • 0033846955 scopus 로고    scopus 로고
    • Expression of human apolipoprotein A-II in apolipoprotein E-deficient mice induces features of familial combined hyperlipidemia
    • Escola-Gil JC, Julve J, Marzal-Casacuberta A, et al. Expression of human apolipoprotein A-II in apolipoprotein E-deficient mice induces features of familial combined hyperlipidemia. J Lipid Res 2000; 41: 1328-38.
    • (2000) J Lipid Res , vol.41 , pp. 1328-1338
    • Escola-Gil, J.C.1    Julve, J.2    Marzal-Casacuberta, A.3
  • 129
    • 0027279942 scopus 로고
    • Atherosclerosis in transgenic mice overexpressing apolipoprotein A-II
    • Warden CH, Hedrick CC, Qiao JH, et al. Atherosclerosis in transgenic mice overexpressing apolipoprotein A-II. Science 1993; 261: 469-72.
    • (1993) Science , vol.261 , pp. 469-472
    • Warden, C.H.1    Hedrick, C.C.2    Qiao, J.H.3
  • 130
    • 31044438421 scopus 로고    scopus 로고
    • Overexpression of human apolipoprotein A-II in transgenic mice does not impair macrophage-specific reverse cholesterol transport in vivo
    • Rotllan N, Ribas V, Calpe-Berdiel L, et al. Overexpression of human apolipoprotein A-II in transgenic mice does not impair macrophage-specific reverse cholesterol transport in vivo. Arterioscler Thromb Vasc Biol 2005; 25: e128-32.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25
    • Rotllan, N.1    Ribas, V.2    Calpe-Berdiel, L.3
  • 131
    • 0030851389 scopus 로고    scopus 로고
    • Overexpression of apolipoprotein AII in transgenic mice converts high density lipoproteins to proinflammatory particles
    • Castellani LW, Navab M, Van Lenten BJ, et al. Overexpression of apolipoprotein AII in transgenic mice converts high density lipoproteins to proinflammatory particles. J Clin Invest 1997; 100: 464-74.
    • (1997) J Clin Invest , vol.100 , pp. 464-474
    • Castellani, L.W.1    Navab, M.2    Van Lenten, B.J.3
  • 132
    • 6344291948 scopus 로고    scopus 로고
    • Human apolipoprotein A-II enrichment displaces paraoxonase from HDL and impairs its antioxidant properties: A new mechanism linking HDL protein composition and antiatherogenic potential
    • Ribas V, Sanchez-Quesada JL, Anton R, et al. Human apolipoprotein A-II enrichment displaces paraoxonase from HDL and impairs its antioxidant properties: a new mechanism linking HDL protein composition and antiatherogenic potential. Circ Res 2004; 95: 789-97.
    • (2004) Circ Res , vol.95 , pp. 789-797
    • Ribas, V.1    Sanchez-Quesada, J.L.2    Anton, R.3
  • 133
    • 33845562454 scopus 로고    scopus 로고
    • Human apolipoprotein A-II associates with triglyceride-rich lipoproteins in plasma and impairs their catabolism
    • Dugue-Pujol S, Rousset X, Pastier D, et al. Human apolipoprotein A-II associates with triglyceride-rich lipoproteins in plasma and impairs their catabolism. J Lipid Res 2006; 47: 2631-9.
    • (2006) J Lipid Res , vol.47 , pp. 2631-2639
    • Dugue-Pujol, S.1    Rousset, X.2    Pastier, D.3
  • 134
    • 45549094126 scopus 로고    scopus 로고
    • Apolipoprotein AII is a regulator of very low density lipoprotein metabolism and insulin resistance
    • Castellani LW, Nguyen CN, Charugundla S, et al. Apolipoprotein AII is a regulator of very low density lipoprotein metabolism and insulin resistance. J Biol Chem 2008; 283: 11633-44.
    • (2008) J Biol Chem , vol.283 , pp. 11633-11644
    • Castellani, L.W.1    Nguyen, C.N.2    Charugundla, S.3
  • 135
    • 75149135220 scopus 로고    scopus 로고
    • Human apolipoprotein A-II determines plasma triglycerides by regulating lipoprotein lipase activity and high-density lipoprotein proteome
    • Julve J, Escola-Gil JC, Rotllan N, et al. Human apolipoprotein A-II determines plasma triglycerides by regulating lipoprotein lipase activity and high-density lipoprotein proteome. Arterioscler Thromb Vasc Biol 2010; 30: 232-8.
    • (2010) Arterioscler Thromb Vasc Biol , vol.30 , pp. 232-238
    • Julve, J.1    Escola-Gil, J.C.2    Rotllan, N.3
  • 136
    • 0033556420 scopus 로고    scopus 로고
    • Molecular cloning and expression of lipid transfer inhibitor protein reveals its identity with apolipoprotein F
    • Wang X, Driscoll DM, Morton RE. Molecular cloning and expression of lipid transfer inhibitor protein reveals its identity with apolipoprotein F. J Biol Chem 1999; 274: 1814-20.
    • (1999) J Biol Chem , vol.274 , pp. 1814-1820
    • Wang, X.1    Driscoll, D.M.2    Morton, R.E.3
  • 137
    • 33847368173 scopus 로고    scopus 로고
    • Shotgun proteomics implicates protease inhibition and complement activation in the antiinflammatory properties of HDL
    • Vaisar T, Pennathur S, Green PS, et al. Shotgun proteomics implicates protease inhibition and complement activation in the antiinflammatory properties of HDL. J Clin Invest 2007; 117: 746-56.
    • (2007) J Clin Invest , vol.117 , pp. 746-756
    • Vaisar, T.1    Pennathur, S.2    Green, P.S.3
  • 138
    • 58849167645 scopus 로고    scopus 로고
    • Overexpression of apolipoprotein F reduces HDL cholesterol levels in vivo
    • Lagor WR, Brown RJ, Toh SA, et al. Overexpression of apolipoprotein F reduces HDL cholesterol levels in vivo. Arterioscler Thromb Vasc Biol 2009; 29: 40-6.
    • (2009) Arterioscler Thromb Vasc Biol , vol.29 , pp. 40-46
    • Lagor, W.R.1    Brown, R.J.2    Toh, S.A.3
  • 139
    • 33947151023 scopus 로고    scopus 로고
    • Role of LCAT in HDL remodeling: Investigation of LCAT deficiency states
    • Asztalos BF, Schaefer EJ, Horvath KV, et al. Role of LCAT in HDL remodeling: investigation of LCAT deficiency states. J Lipid Res 2007; 48: 592-9.
    • (2007) J Lipid Res , vol.48 , pp. 592-599
    • Asztalos, B.F.1    Schaefer, E.J.2    Horvath, K.V.3
  • 140
    • 13244266993 scopus 로고    scopus 로고
    • Lipid transfer proteins (LTP) and atherosclerosis
    • Stein O, Stein Y. Lipid transfer proteins (LTP) and atherosclerosis. Atherosclerosis 2005; 178: 217-30.
    • (2005) Atherosclerosis , vol.178 , pp. 217-230
    • Stein, O.1    Stein, Y.2
  • 141
    • 0034087304 scopus 로고    scopus 로고
    • Lecithin- cholesterol acyltransferase: Role in lipoprotein metabolism, reverse cholesterol transport and atherosclerosis
    • Santamarina-Fojo S, Lambert G, Hoeg JM, Brewer HB, Jr. Lecithin- cholesterol acyltransferase: role in lipoprotein metabolism, reverse cholesterol transport and atherosclerosis. Curr Opin Lipidol 2000; 11: 267-75.
    • (2000) Curr Opin Lipidol , vol.11 , pp. 267-275
    • Santamarina-Fojo, S.1    Lambert, G.2    Hoeg, J.M.3    Brewer Jr., H.B.4
  • 142
    • 17144407981 scopus 로고    scopus 로고
    • Inherited disorders of HDL metabolism and atherosclerosis
    • Hovingh GK, de Groot E, van der Steeg W, et al. Inherited disorders of HDL metabolism and atherosclerosis. Curr Opin Lipidol 2005; 16: 139-45.
    • (2005) Curr Opin Lipidol , vol.16 , pp. 139-145
    • Hovingh, G.K.1    de Groot, E.2    van der Steeg, W.3
  • 143
    • 67651085117 scopus 로고    scopus 로고
    • Lecithin: Cholesterol acyltransferase expression has minimal effects on macrophage reverse cholesterol transport in vivo
    • Tanigawa H, Billheimer JT, Tohyama J, et al. Lecithin: cholesterol acyltransferase expression has minimal effects on macrophage reverse cholesterol transport in vivo. Circulation 2009; 120: 160-9.
    • (2009) Circulation , vol.120 , pp. 160-169
    • Tanigawa, H.1    Billheimer, J.T.2    Tohyama, J.3
  • 144
    • 0344429365 scopus 로고    scopus 로고
    • High plasma HDL concentrations associated with enhanced atherosclerosis in transgenic mice overexpressing lecithin-cholesteryl acyltransferase
    • Berard AM, Foger B, Remaley A, et al. High plasma HDL concentrations associated with enhanced atherosclerosis in transgenic mice overexpressing lecithin-cholesteryl acyltransferase. Nat Med 1997; 3: 744-9.
    • (1997) Nat Med , vol.3 , pp. 744-749
    • Berard, A.M.1    Foger, B.2    Remaley, A.3
  • 145
    • 0030812633 scopus 로고    scopus 로고
    • Mice overexpressing human lecithin: Cholesterol acyltransferase are not protected against dietinduced atherosclerosis
    • Mehlum A, Muri M, Hagve TA, et al. Mice overexpressing human lecithin: cholesterol acyltransferase are not protected against dietinduced atherosclerosis. APMIS 1997; 105: 861-8.
    • (1997) APMIS , vol.105 , pp. 861-868
    • Mehlum, A.1    Muri, M.2    Hagve, T.A.3
  • 146
    • 0036827813 scopus 로고    scopus 로고
    • Transgenic overexpression of human lecithin: Cholesterol acyltransferase (LCAT) in mice does not increase aortic cholesterol deposition
    • Furbee JW, Jr., Parks JS. Transgenic overexpression of human lecithin: cholesterol acyltransferase (LCAT) in mice does not increase aortic cholesterol deposition. Atherosclerosis 2002; 165: 89-100.
    • (2002) Atherosclerosis , vol.165 , pp. 89-100
    • Furbee Jr., J.W.1    Parks, J.S.2
  • 147
    • 0039552128 scopus 로고    scopus 로고
    • Cholesteryl ester transfer protein corrects dysfunctional high density lipoproteins and reduces aortic atherosclerosis in lecithin cholesterol acyltransferase transgenic mice
    • Foger B, Chase M, Amar MJ, et al. Cholesteryl ester transfer protein corrects dysfunctional high density lipoproteins and reduces aortic atherosclerosis in lecithin cholesterol acyltransferase transgenic mice. J Biol Chem 1999; 274: 36912-20.
    • (1999) J Biol Chem , vol.274 , pp. 36912-36920
    • Foger, B.1    Chase, M.2    Amar, M.J.3
  • 148
    • 0035805531 scopus 로고    scopus 로고
    • Analysis of glomerulosclerosis and atherosclerosis in lecithin cholesterol acyltransferasedeficient mice
    • Lambert G, Sakai N, Vaisman BL, et al. Analysis of glomerulosclerosis and atherosclerosis in lecithin cholesterol acyltransferasedeficient mice. J Biol Chem 2001; 276: 15090-8.
    • (2001) J Biol Chem , vol.276 , pp. 15090-15098
    • Lambert, G.1    Sakai, N.2    Vaisman, B.L.3
  • 149
    • 0036479142 scopus 로고    scopus 로고
    • Lecithin:Cholesterol acyltransferase deficiency increases atherosclerosis in the low density lipoprotein receptor and apolipoprotein E knockout mice
    • Furbee JW, Jr., Sawyer JK, Parks JS. Lecithin:cholesterol acyltransferase deficiency increases atherosclerosis in the low density lipoprotein receptor and apolipoprotein E knockout mice. J Biol Chem 2002; 277: 3511-9.
    • (2002) J Biol Chem , vol.277 , pp. 3511-3519
    • Furbee Jr., J.W.1    Sawyer, J.K.2    Parks, J.S.3
  • 150
    • 0037023773 scopus 로고    scopus 로고
    • Oxidative stress is markedly elevated in lecithin:Cholesterol acyltransferase-deficient mice and is paradoxically reversed in the apolipoprotein E knockout background in association with a reduction in atherosclerosis
    • Ng DS, Maguire GF, Wylie J, et al. Oxidative stress is markedly elevated in lecithin:cholesterol acyltransferase-deficient mice and is paradoxically reversed in the apolipoprotein E knockout background in association with a reduction in atherosclerosis. J Biol Chem 2002; 277: 11715-20.
    • (2002) J Biol Chem , vol.277 , pp. 11715-11720
    • Ng, D.S.1    Maguire, G.F.2    Wylie, J.3
  • 151
    • 67349250436 scopus 로고    scopus 로고
    • Functional LCAT is not required for macrophage cholesterol efflux to human serum
    • Calabresi L, Favari E, Moleri E, et al. Functional LCAT is not required for macrophage cholesterol efflux to human serum. Atherosclerosis 2009; 204: 141-6.
    • (2009) Atherosclerosis , vol.204 , pp. 141-146
    • Calabresi, L.1    Favari, E.2    Moleri, E.3
  • 152
    • 24344452861 scopus 로고    scopus 로고
    • High-density lipoproteins attenuate interleukin-6 production in endothelial cells exposed to pro-inflammatory stimuli
    • Gomaraschi M, Basilico N, Sisto F, et al. High-density lipoproteins attenuate interleukin-6 production in endothelial cells exposed to pro-inflammatory stimuli. Biochim Biophys Acta 2005; 1736: 136-43.
    • (2005) Biochim Biophys Acta , vol.1736 , pp. 136-143
    • Gomaraschi, M.1    Basilico, N.2    Sisto, F.3
  • 153
    • 69549103151 scopus 로고    scopus 로고
    • Functional lecithin: Cholesterol acyltransferase is not required for efficient atheroprotection in humans
    • Calabresi L, Baldassarre D, Castelnuovo S, et al. Functional lecithin: cholesterol acyltransferase is not required for efficient atheroprotection in humans. Circulation 2009; 120: 628-35.
    • (2009) Circulation , vol.120 , pp. 628-635
    • Calabresi, L.1    Baldassarre, D.2    Castelnuovo, S.3
  • 154
    • 77949498424 scopus 로고    scopus 로고
    • Plasma levels of lecithin:Cholesterol acyltransferase and risk of future coronary artery disease in apparently healthy men and women: A prospective case-control analysis nested in the EPIC-Norfolk population study
    • Holleboom AG, Kuivenhoven JA, Vergeer M, et al. Plasma levels of lecithin:cholesterol acyltransferase and risk of future coronary artery disease in apparently healthy men and women: a prospective case-control analysis nested in the EPIC-Norfolk population study. J Lipid Res 51: 416-21.
    • J Lipid Res , vol.51 , pp. 416-421
    • Holleboom, A.G.1    Kuivenhoven, J.A.2    Vergeer, M.3
  • 155
    • 0028305216 scopus 로고
    • Complete cDNA encoding human phospholipid transfer protein from human endothelial cells
    • Day JR, Albers JJ, Lofton-Day CE, et al. Complete cDNA encoding human phospholipid transfer protein from human endothelial cells. J Biol Chem 1994; 269: 9388-91.
    • (1994) J Biol Chem , vol.269 , pp. 9388-9391
    • Day, J.R.1    Albers, J.J.2    Lofton-Day, C.E.3
  • 156
    • 0029096429 scopus 로고
    • Functional expression of human and mouse plasma phospholipid transfer protein: Effect of recombinant and plasma PLTP on HDL subspecies
    • Albers JJ, Wolfbauer G, Cheung MC, et al. Functional expression of human and mouse plasma phospholipid transfer protein: effect of recombinant and plasma PLTP on HDL subspecies. Biochim Biophys Acta 1995; 1258: 27-34.
    • (1995) Biochim Biophys Acta , vol.1258 , pp. 27-34
    • Albers, J.J.1    Wolfbauer, G.2    Cheung, M.C.3
  • 157
    • 0027469774 scopus 로고
    • Human plasma phospholipid transfer protein causes high density lipoprotein conversion
    • Jauhiainen M, Metso J, Pahlman R, et al. Human plasma phospholipid transfer protein causes high density lipoprotein conversion. J Biol Chem 1993; 268: 4032-6.
    • (1993) J Biol Chem , vol.268 , pp. 4032-4036
    • Jauhiainen, M.1    Metso, J.2    Pahlman, R.3
  • 158
    • 0027451376 scopus 로고
    • High density lipoprotein conversion mediated by human plasma phospholipid transfer protein
    • Tu AY, Nishida HI, Nishida T. High density lipoprotein conversion mediated by human plasma phospholipid transfer protein. J Biol Chem 1993; 268: 23098-105.
    • (1993) J Biol Chem , vol.268 , pp. 23098-23105
    • Tu, A.Y.1    Nishida, H.I.2    Nishida, T.3
  • 159
    • 0034037688 scopus 로고    scopus 로고
    • Human plasma phospholipid transfer protein increases the antiatherogenic potential of high density lipoproteins in transgenic mice
    • van Haperen R, van Tol A, Vermeulen P, et al. Human plasma phospholipid transfer protein increases the antiatherogenic potential of high density lipoproteins in transgenic mice. Arterioscler Thromb Vasc Biol 2000; 20: 1082-8.
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 1082-1088
    • van Haperen, R.1    van Tol, A.2    Vermeulen, P.3
  • 160
    • 2242428907 scopus 로고    scopus 로고
    • Increased risk of atherosclerosis by elevated plasma levels of phospholipid transfer protein
    • van Haperen R, van Tol A, van Gent T, et al. Increased risk of atherosclerosis by elevated plasma levels of phospholipid transfer protein. J Biol Chem 2002; 277: 48938-43.
    • (2002) J Biol Chem , vol.277 , pp. 48938-48943
    • van Haperen, R.1    van Tol, A.2    van Gent, T.3
  • 161
    • 2142751025 scopus 로고    scopus 로고
    • Elevation of plasma phospholipid transfer protein increases the risk of atherosclerosis despite lower apolipoprotein B-containing lipoproteins
    • Lie J, de Crom R, van Gent T, et al. Elevation of plasma phospholipid transfer protein increases the risk of atherosclerosis despite lower apolipoprotein B-containing lipoproteins. J Lipid Res 2004; 45: 805-11.
    • (2004) J Lipid Res , vol.45 , pp. 805-811
    • Lie, J.1    de Crom, R.2    van Gent, T.3
  • 162
    • 10744220804 scopus 로고    scopus 로고
    • Increased atherosclerotic lesions in apoE mice with plasma phospholipid transfer protein overexpression
    • Yang XP, Yan D, Qiao C, et al. Increased atherosclerotic lesions in apoE mice with plasma phospholipid transfer protein overexpression. Arterioscler Thromb Vasc Biol 2003; 23: 1601-7.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 1601-1607
    • Yang, X.P.1    Yan, D.2    Qiao, C.3
  • 163
    • 67349151089 scopus 로고    scopus 로고
    • Elevation of systemic PLTP, but not macrophage-PLTP, impairs macrophage reverse cholesterol transport in transgenic mice
    • Samyn H, Moerland M, van Gent T, et al. Elevation of systemic PLTP, but not macrophage-PLTP, impairs macrophage reverse cholesterol transport in transgenic mice. Atherosclerosis 2009; 204: 429-34.
    • (2009) Atherosclerosis , vol.204 , pp. 429-434
    • Samyn, H.1    Moerland, M.2    van Gent, T.3
  • 164
    • 0034920010 scopus 로고    scopus 로고
    • Apolipoprotein B secretion and atherosclerosis are decreased in mice with phospholipid-transfer protein deficiency
    • Jiang XC, Qin S, Qiao C, et al. Apolipoprotein B secretion and atherosclerosis are decreased in mice with phospholipid-transfer protein deficiency. Nat Med 2001; 7: 847-52.
    • (2001) Nat Med , vol.7 , pp. 847-852
    • Jiang, X.C.1    Qin, S.2    Qiao, C.3
  • 165
    • 16644402295 scopus 로고    scopus 로고
    • PLTP deficiency improves the anti-inflammatory properties of HDL and reduces the ability of LDL to induce monocyte chemotactic activity
    • Yan D, Navab M, Bruce C, et al. PLTP deficiency improves the anti-inflammatory properties of HDL and reduces the ability of LDL to induce monocyte chemotactic activity. J Lipid Res 2004; 45: 1852-8.
    • (2004) J Lipid Res , vol.45 , pp. 1852-1858
    • Yan, D.1    Navab, M.2    Bruce, C.3
  • 166
    • 0141919768 scopus 로고    scopus 로고
    • High plasma phospholipid transfer protein levels as a risk factor for coronary artery disease
    • Schlitt A, Bickel C, Thumma P, et al. High plasma phospholipid transfer protein levels as a risk factor for coronary artery disease. Arterioscler Thromb Vasc Biol 2003; 23: 1857-62.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 1857-1862
    • Schlitt, A.1    Bickel, C.2    Thumma, P.3
  • 167
    • 67449123466 scopus 로고    scopus 로고
    • PLTP activity is a risk factor for subsequent cardiovascular events in CAD patients under statin therapy: The AtheroGene study
    • Schlitt A, Blankenberg S, Bickel C, et al. PLTP activity is a risk factor for subsequent cardiovascular events in CAD patients under statin therapy: the AtheroGene study. J Lipid Res 2009; 50: 723-9.
    • (2009) J Lipid Res , vol.50 , pp. 723-729
    • Schlitt, A.1    Blankenberg, S.2    Bickel, C.3
  • 168
    • 0041807631 scopus 로고    scopus 로고
    • Cell-associated and extracellular phospholipid transfer protein in human coronary atherosclerosis
    • O'Brien KD, Vuletic S, McDonald TO, et al. Cell-associated and extracellular phospholipid transfer protein in human coronary atherosclerosis. Circulation 2003; 108: 270-4.
    • (2003) Circulation , vol.108 , pp. 270-274
    • O'Brien, K.D.1    Vuletic, S.2    McDonald, T.O.3
  • 169
    • 0142042404 scopus 로고    scopus 로고
    • Phospholipid transfer protein is present in human atherosclerotic lesions and is expressed by macrophages and foam cells
    • Desrumaux CM, Mak PA, Boisvert WA, et al. Phospholipid transfer protein is present in human atherosclerotic lesions and is expressed by macrophages and foam cells. J Lipid Res 2003; 44: 1453-61.
    • (2003) J Lipid Res , vol.44 , pp. 1453-1461
    • Desrumaux, C.M.1    Mak, P.A.2    Boisvert, W.A.3
  • 170
    • 33847647524 scopus 로고    scopus 로고
    • Macrophage phospholipid transfer protein deficiency and ApoE secretion: Impact on mouse plasma cholesterol levels and atherosclerosis
    • Liu R, Hojjati MR, Devlin CM, et al. Macrophage phospholipid transfer protein deficiency and ApoE secretion: impact on mouse plasma cholesterol levels and atherosclerosis. Arterioscler Thromb Vasc Biol 2007; 27: 190-6.
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , pp. 190-196
    • Liu, R.1    Hojjati, M.R.2    Devlin, C.M.3
  • 171
    • 33745955859 scopus 로고    scopus 로고
    • Atheroprotective potential of macrophage-derived phospholipid transfer protein in lowdensity lipoprotein receptor-deficient mice is overcome by apolipoprotein AI overexpression
    • Valenta DT, Ogier N, Bradshaw G, et al. Atheroprotective potential of macrophage-derived phospholipid transfer protein in lowdensity lipoprotein receptor-deficient mice is overcome by apolipoprotein AI overexpression. Arterioscler Thromb Vasc Biol 2006; 26: 1572-8.
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , pp. 1572-1578
    • Valenta, D.T.1    Ogier, N.2    Bradshaw, G.3
  • 172
    • 38049098116 scopus 로고    scopus 로고
    • Macrophage PLTP is atheroprotective in LDLr-deficient mice with systemic PLTP deficiency
    • Valenta DT, Bulgrien JJ, Bonnet DJ, Curtiss LK. Macrophage PLTP is atheroprotective in LDLr-deficient mice with systemic PLTP deficiency. J Lipid Res 2008; 49: 24-32.
    • (2008) J Lipid Res , vol.49 , pp. 24-32
    • Valenta, D.T.1    Bulgrien, J.J.2    Bonnet, D.J.3    Curtiss, L.K.4
  • 173
    • 48249142373 scopus 로고    scopus 로고
    • Elevated expression of phospholipid transfer protein in bone marrow derived cells causes atherosclerosis
    • van Haperen R, Samyn H, Moerland M, et al. Elevated expression of phospholipid transfer protein in bone marrow derived cells causes atherosclerosis. PLoS One 2008; 3: e2255.
    • (2008) PLoS One , vol.3
    • van Haperen, R.1    Samyn, H.2    Moerland, M.3
  • 174
    • 36049014905 scopus 로고    scopus 로고
    • Cholesterol accumulation is increased in macrophages of phospholipid transfer protein-deficient mice: Normalization by dietary alpha-tocopherol supplementation
    • Ogier N, Klein A, Deckert V, et al. Cholesterol accumulation is increased in macrophages of phospholipid transfer protein-deficient mice: normalization by dietary alpha-tocopherol supplementation. Arterioscler Thromb Vasc Biol 2007; 27: 2407-12.
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , pp. 2407-2412
    • Ogier, N.1    Klein, A.2    Deckert, V.3
  • 175
    • 74549148035 scopus 로고    scopus 로고
    • Cholesteryl ester transfer protein: At the heart of the action of lipid-modulating therapy with statins, fibrates, niacin, and cholesteryl ester transfer protein inhibitors
    • Chapman MJ, Le Goff W, Guerin M, Kontush A. Cholesteryl ester transfer protein: at the heart of the action of lipid-modulating therapy with statins, fibrates, niacin, and cholesteryl ester transfer protein inhibitors. Eur Heart J 2010; 31(2): 149-64.
    • (2010) Eur Heart J , vol.31 , Issue.2 , pp. 149-164
    • Chapman, M.J.1    Le Goff, W.2    Guerin, M.3    Kontush, A.4
  • 176
    • 14944381287 scopus 로고    scopus 로고
    • HDL as a target in the treatment of atherosclerotic cardiovascular disease
    • Linsel-Nitschke P, Tall AR. HDL as a target in the treatment of atherosclerotic cardiovascular disease. Nat Rev Drug Discov 2005; 4: 193-205.
    • (2005) Nat Rev Drug Discov , vol.4 , pp. 193-205
    • Linsel-Nitschke, P.1    Tall, A.R.2
  • 177
    • 2142763867 scopus 로고    scopus 로고
    • A prospective study of HDL-C and cholesteryl ester transfer protein gene mutations and the risk of coronary heart disease in the elderly
    • Curb JD, Abbott RD, Rodriguez BL, et al. A prospective study of HDL-C and cholesteryl ester transfer protein gene mutations and the risk of coronary heart disease in the elderly. J Lipid Res 2004; 45: 948-53.
    • (2004) J Lipid Res , vol.45 , pp. 948-953
    • Curb, J.D.1    Abbott, R.D.2    Rodriguez, B.L.3
  • 178
    • 33947180987 scopus 로고    scopus 로고
    • CETP expression enhances liver HDL-cholesteryl ester uptake but does not alter VLDL and biliary lipid secretion
    • Harada LM, Amigo L, Cazita PM, et al. CETP expression enhances liver HDL-cholesteryl ester uptake but does not alter VLDL and biliary lipid secretion. Atherosclerosis 2007; 191(2): 313-8.
    • (2007) Atherosclerosis , vol.191 , Issue.2 , pp. 313-318
    • Harada, L.M.1    Amigo, L.2    Cazita, P.M.3
  • 179
    • 38349131657 scopus 로고    scopus 로고
    • CETP activity variation in mice does not affect two major HDL antiatherogenic properties: Macrophage-specific reverse cholesterol transport and LDL antioxidant protection
    • Rotllan N, Calpe-Berdiel L, Guillaumet-Adkins A, et al. CETP activity variation in mice does not affect two major HDL antiatherogenic properties: macrophage-specific reverse cholesterol transport and LDL antioxidant protection. Atherosclerosis 2008; 196: 505-13.
    • (2008) Atherosclerosis , vol.196 , pp. 505-513
    • Rotllan, N.1    Calpe-Berdiel, L.2    Guillaumet-Adkins, A.3
  • 180
    • 34948860018 scopus 로고    scopus 로고
    • Expression of cholesteryl ester transfer protein in mice promotes macrophage reverse cholesterol transport
    • Tanigawa H, Billheimer JT, Tohyama J, et al. Expression of cholesteryl ester transfer protein in mice promotes macrophage reverse cholesterol transport. Circulation 2007; 116: 1267-73.
    • (2007) Circulation , vol.116 , pp. 1267-1273
    • Tanigawa, H.1    Billheimer, J.T.2    Tohyama, J.3
  • 181
    • 39749120838 scopus 로고    scopus 로고
    • The effect of cholesteryl ester transfer protein overexpression and inhibition on reverse cholesterol transport
    • Tchoua U, D'Souza W, Mukhamedova N, et al. The effect of cholesteryl ester transfer protein overexpression and inhibition on reverse cholesterol transport. Cardiovasc Res 2008; 77: 732-9.
    • (2008) Cardiovasc Res , vol.77 , pp. 732-739
    • Tchoua, U.1    D'Souza, W.2    Mukhamedova, N.3
  • 182
    • 0027325516 scopus 로고
    • Severe atherosclerosis in transgenic mice expressing simian cholesteryl ester transfer protein
    • Marotti KR, Castle CK, Boyle TP, et al. Severe atherosclerosis in transgenic mice expressing simian cholesteryl ester transfer protein. Nature 1993; 364: 73-5.
    • (1993) Nature , vol.364 , pp. 73-75
    • Marotti, K.R.1    Castle, C.K.2    Boyle, T.P.3
  • 183
    • 0028784246 scopus 로고
    • Decreased early atherosclerotic lesions in hypertriglyceridemic mice expressing cholesteryl ester transfer protein transgene
    • Hayek T, Masucci-Magoulas L, Jiang X, et al. Decreased early atherosclerotic lesions in hypertriglyceridemic mice expressing cholesteryl ester transfer protein transgene. J Clin Invest 1995; 96: 2071-4.
    • (1995) J Clin Invest , vol.96 , pp. 2071-2074
    • Hayek, T.1    Masucci-Magoulas, L.2    Jiang, X.3
  • 184
    • 0032917975 scopus 로고    scopus 로고
    • Increased atherosclerosis in ApoE and LDL receptor gene knock-out mice as a result of human cholesteryl ester transfer protein transgene expression
    • Plump AS, Masucci-Magoulas L, Bruce C, et al. Increased atherosclerosis in ApoE and LDL receptor gene knock-out mice as a result of human cholesteryl ester transfer protein transgene expression. Arterioscler Thromb Vasc Biol 1999; 19: 1105-10.
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 1105-1110
    • Plump, A.S.1    Masucci-Magoulas, L.2    Bruce, C.3
  • 185
    • 33750213836 scopus 로고    scopus 로고
    • Cholesteryl ester transfer protein decreases high-density lipoprotein and severely aggravates atherosclerosis in APOE*3-Leiden mice
    • Westerterp M, van der Hoogt CC, de Haan W, et al. Cholesteryl ester transfer protein decreases high-density lipoprotein and severely aggravates atherosclerosis in APOE*3-Leiden mice. Arterioscler Thromb Vasc Biol 2006; 26: 2552-9.
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , pp. 2552-2559
    • Westerterp, M.1    van der Hoogt, C.C.2    de Haan, W.3
  • 186
    • 33947729888 scopus 로고    scopus 로고
    • Important role for bone marrow-derived cholesteryl ester transfer protein in lipoprotein cholesterol redistribution and atherosclerotic lesion development in LDL receptor knockout mice
    • Van Eck M, Ye D, Hildebrand RB, et al. Important role for bone marrow-derived cholesteryl ester transfer protein in lipoprotein cholesterol redistribution and atherosclerotic lesion development in LDL receptor knockout mice. Circ Res 2007; 100: 678-85.
    • (2007) Circ Res , vol.100 , pp. 678-685
    • Van Eck, M.1    Ye, D.2    Hildebrand, R.B.3
  • 187
    • 0344406740 scopus 로고    scopus 로고
    • Endothelial lipase is a major genetic determinant for high-density lipoprotein concentration, structure, and metabolism
    • Ma K, Cilingiroglu M, Otvos JD, et al. Endothelial lipase is a major genetic determinant for high-density lipoprotein concentration, structure, and metabolism. Proc Natl Acad Sci USA 2003; 100: 2748-53.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 2748-2753
    • Ma, K.1    Cilingiroglu, M.2    Otvos, J.D.3
  • 188
    • 1842452934 scopus 로고    scopus 로고
    • Endothelial lipase and HDL metabolism
    • Jaye M, Krawiec J. Endothelial lipase and HDL metabolism. Curr Opin Lipidol 2004; 15: 183-9.
    • (2004) Curr Opin Lipidol , vol.15 , pp. 183-189
    • Jaye, M.1    Krawiec, J.2
  • 189
    • 70350351093 scopus 로고    scopus 로고
    • A naturally occurring variant of endothelial lipase associated with elevated HDL exhibits impaired synthesis
    • Brown RJ, Edmondson AC, Griffon N, et al. A naturally occurring variant of endothelial lipase associated with elevated HDL exhibits impaired synthesis. J Lipid Res 2009; 50: 1910-6.
    • (2009) J Lipid Res , vol.50 , pp. 1910-1916
    • Brown, R.J.1    Edmondson, A.C.2    Griffon, N.3
  • 190
    • 65249186429 scopus 로고    scopus 로고
    • Loss-of-function variants in endothelial lipase are a cause of elevated HDL cholesterol in humans
    • Edmondson AC, Brown RJ, Kathiresan S, et al. Loss-of-function variants in endothelial lipase are a cause of elevated HDL cholesterol in humans. J Clin Invest 2009; 119: 1042-50.
    • (2009) J Clin Invest , vol.119 , pp. 1042-1050
    • Edmondson, A.C.1    Brown, R.J.2    Kathiresan, S.3
  • 191
    • 0032901331 scopus 로고    scopus 로고
    • A novel endothelial-derived lipase that modulates HDL metabolism
    • Jaye M, Lynch KJ, Krawiec J, et al. A novel endothelial-derived lipase that modulates HDL metabolism. Nat Genet 1999; 21: 424-8.
    • (1999) Nat Genet , vol.21 , pp. 424-428
    • Jaye, M.1    Lynch, K.J.2    Krawiec, J.3
  • 192
    • 0037314398 scopus 로고    scopus 로고
    • Endothelial lipase is a major determinant of HDL level
    • Ishida T, Choi S, Kundu RK, et al. Endothelial lipase is a major determinant of HDL level. J Clin Invest 2003; 111: 347-55.
    • (2003) J Clin Invest , vol.111 , pp. 347-355
    • Ishida, T.1    Choi, S.2    Kundu, R.K.3
  • 193
    • 34547571901 scopus 로고    scopus 로고
    • Hepatic proprotein convertases modulate HDL metabolism
    • Jin W, Wang X, Millar JS, et al. Hepatic proprotein convertases modulate HDL metabolism. Cell Metab 2007; 6: 129-36.
    • (2007) Cell Metab , vol.6 , pp. 129-136
    • Jin, W.1    Wang, X.2    Millar, J.S.3
  • 194
    • 7244229703 scopus 로고    scopus 로고
    • Endothelial lipase modulates susceptibility to atherosclerosis in apolipoprotein-E-deficient mice
    • Ishida T, Choi SY, Kundu RK, et al. Endothelial lipase modulates susceptibility to atherosclerosis in apolipoprotein-E-deficient mice. J Biol Chem 2004; 279: 45085-92.
    • (2004) J Biol Chem , vol.279 , pp. 45085-45092
    • Ishida, T.1    Choi, S.Y.2    Kundu, R.K.3
  • 195
    • 30844437283 scopus 로고    scopus 로고
    • Endothelial lipase modulates HDL but has no effect on atherosclerosis development in apoE-/- and LDLR-/- mice
    • Ko KW, Paul A, Ma K, et al. Endothelial lipase modulates HDL but has no effect on atherosclerosis development in apoE-/- and LDLR-/- mice. J Lipid Res 2005; 46: 2586-94.
    • (2005) J Lipid Res , vol.46 , pp. 2586-2594
    • Ko, K.W.1    Paul, A.2    Ma, K.3
  • 196
    • 34547858847 scopus 로고    scopus 로고
    • High-density lipoprotein as a therapeutic target: A systematic review
    • Singh IM, Shishehbor MH, Ansell BJ. High-density lipoprotein as a therapeutic target: a systematic review. JAMA 2007; 298: 786-98.
    • (2007) JAMA , vol.298 , pp. 786-798
    • Singh, I.M.1    Shishehbor, M.H.2    Ansell, B.J.3
  • 197
    • 50649089597 scopus 로고    scopus 로고
    • Fibrates and future PPARalpha agonists in the treatment of cardiovascular disease
    • Staels B, Maes M, Zambon A. Fibrates and future PPARalpha agonists in the treatment of cardiovascular disease. Nat Clin Pract Cardiovasc Med 2008; 5: 542-53.
    • (2008) Nat Clin Pract Cardiovasc Med , vol.5 , pp. 542-553
    • Staels, B.1    Maes, M.2    Zambon, A.3
  • 198
    • 73849086222 scopus 로고    scopus 로고
    • Combination therapy of statins and fibrates in the management of cardiovascular risk
    • Fievet C, Staels B. Combination therapy of statins and fibrates in the management of cardiovascular risk. Curr Opin Lipidol 2009; 20: 505-11.
    • (2009) Curr Opin Lipidol , vol.20 , pp. 505-511
    • Fievet, C.1    Staels, B.2
  • 199
    • 44649090091 scopus 로고    scopus 로고
    • High-density lipoprotein and atheroma monitoring
    • Nicholls SJ, Tuzcu EM. High-density lipoprotein and atheroma monitoring. Curr Opin Cardiol 2008; 23: 386-92.
    • (2008) Curr Opin Cardiol , vol.23 , pp. 386-392
    • Nicholls, S.J.1    Tuzcu, E.M.2
  • 200
    • 44649143930 scopus 로고    scopus 로고
    • Acute effects of high-density lipoproteins: Biochemical basis and clinical findings
    • Chiesa G, Parolini C, Sirtori CR. Acute effects of high-density lipoproteins: biochemical basis and clinical findings. Curr Opin Cardiol 2008; 23: 379-85.
    • (2008) Curr Opin Cardiol , vol.23 , pp. 379-385
    • Chiesa, G.1    Parolini, C.2    Sirtori, C.R.3
  • 201
    • 53849127157 scopus 로고    scopus 로고
    • High density lipoprotein cholesterol and statin trials
    • Kakafika A, Athyros VG, Tziomalos K, et al. High density lipoprotein cholesterol and statin trials. Curr Med Chem 2008; 15: 2265-70.
    • (2008) Curr Med Chem , vol.15 , pp. 2265-2270
    • Kakafika, A.1    Athyros, V.G.2    Tziomalos, K.3
  • 202
    • 69749115691 scopus 로고    scopus 로고
    • Enhancing cardiovascular disease risk reduction: Raising high-density lipoprotein levels
    • Hausenloy DJ, Yellon DM. Enhancing cardiovascular disease risk reduction: raising high-density lipoprotein levels. Curr Opin Cardiol 2009; 24: 473-82.
    • (2009) Curr Opin Cardiol , vol.24 , pp. 473-482
    • Hausenloy, D.J.1    Yellon, D.M.2
  • 203
    • 1842815777 scopus 로고    scopus 로고
    • Effects of an inhibitor of cholesteryl ester transfer protein on HDL cholesterol
    • Brousseau ME, Schaefer EJ, Wolfe ML, et al. Effects of an inhibitor of cholesteryl ester transfer protein on HDL cholesterol. N Engl J Med 2004; 350: 1505-15.
    • (2004) N Engl J Med , vol.350 , pp. 1505-1515
    • Brousseau, M.E.1    Schaefer, E.J.2    Wolfe, M.L.3
  • 204
    • 33846424247 scopus 로고    scopus 로고
    • The failure of torcetrapib: Was it the molecule or the mechanism?
    • Tall AR, Yvan-Charvet L, Wang N. The failure of torcetrapib: was it the molecule or the mechanism? Arterioscler Thromb Vasc Biol 2007; 27: 257-60.
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , pp. 257-260
    • Tall, A.R.1    Yvan-Charvet, L.2    Wang, N.3
  • 205
    • 73349122606 scopus 로고    scopus 로고
    • Association of circulating cholesteryl ester transfer protein activity with incidence of cardiovascular disease in the community
    • Vasan RS, Pencina MJ, Robins SJ, et al. Association of circulating cholesteryl ester transfer protein activity with incidence of cardiovascular disease in the community. Circulation 2009; 120: 2414-20.
    • (2009) Circulation , vol.120 , pp. 2414-2420
    • Vasan, R.S.1    Pencina, M.J.2    Robins, S.J.3
  • 206
    • 0028096008 scopus 로고
    • High density lipoproteins with differing apolipoproteins: Relationships to postprandial lipemia, cholesteryl ester transfer protein, and activities of lipoprotein lipase, hepatic lipase, and lecithin: Cholesterol acyltransferase
    • Mowri HO, Patsch JR, Ritsch A, et al. High density lipoproteins with differing apolipoproteins: relationships to postprandial lipemia, cholesteryl ester transfer protein, and activities of lipoprotein lipase, hepatic lipase, and lecithin: cholesterol acyltransferase. J Lipid Res 1994; 35: 291-300.
    • (1994) J Lipid Res , vol.35 , pp. 291-300
    • Mowri, H.O.1    Patsch, J.R.2    Ritsch, A.3
  • 207
    • 33646409606 scopus 로고    scopus 로고
    • HDL from CETP-deficient subjects shows enhanced ability to promote cholesterol efflux from macrophages in an apoE- and ABCG1-dependent pathway
    • Matsuura F, Wang N, Chen W, et al. HDL from CETP-deficient subjects shows enhanced ability to promote cholesterol efflux from macrophages in an apoE- and ABCG1-dependent pathway. J Clin Invest 2006; 116: 1435-42.
    • (2006) J Clin Invest , vol.116 , pp. 1435-1442
    • Matsuura, F.1    Wang, N.2    Chen, W.3
  • 208
    • 33646689775 scopus 로고    scopus 로고
    • Effect of inhibiting cholesteryl ester transfer protein on the kinetics of high-density lipoprotein cholesteryl ester transport in plasma: In vivo studies in rabbits
    • Kee P, Caiazza D, Rye KA, et al. Effect of inhibiting cholesteryl ester transfer protein on the kinetics of high-density lipoprotein cholesteryl ester transport in plasma: in vivo studies in rabbits. Arterioscler Thromb Vasc Biol 2006; 26: 884-90.
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , pp. 884-890
    • Kee, P.1    Caiazza, D.2    Rye, K.A.3
  • 209
    • 43449114204 scopus 로고    scopus 로고
    • Torcetrapib does not reduce atherosclerosis beyond atorvastatin and induces more proinflammatory lesions than atorvastatin
    • de Haan W, de Vries-van der Weij J, van der Hoorn JW, et al. Torcetrapib does not reduce atherosclerosis beyond atorvastatin and induces more proinflammatory lesions than atorvastatin. Circulation 2008; 117: 2515-22.
    • (2008) Circulation , vol.117 , pp. 2515-2522
    • de Haan, W.1    de Vries-van der Weij, J.2    van der Hoorn, J.W.3
  • 210
    • 36549078679 scopus 로고    scopus 로고
    • Effect of the cholesteryl ester transfer protein inhibitor, anacetrapib, on lipoproteins in patients with dyslipidaemia and on 24-h ambulatory blood pressure in healthy individuals: Two double-blind, randomised placebocontrolled phase I studies
    • Krishna R, Anderson MS, Bergman AJ, et al. Effect of the cholesteryl ester transfer protein inhibitor, anacetrapib, on lipoproteins in patients with dyslipidaemia and on 24-h ambulatory blood pressure in healthy individuals: two double-blind, randomised placebocontrolled phase I studies. Lancet 2007; 370: 1907-14.
    • (2007) Lancet , vol.370 , pp. 1907-1914
    • Krishna, R.1    Anderson, M.S.2    Bergman, A.J.3
  • 211
    • 56549117314 scopus 로고    scopus 로고
    • Multiple-Dose Pharmacodynamics and Pharmacokinetics of Anacetrapib, a Potent Cholesteryl Ester Transfer Protein (CETP) Inhibitor, in Healthy Subjects
    • Krishna R, Bergman A, Jin B, et al. Multiple-Dose Pharmacodynamics and Pharmacokinetics of Anacetrapib, a Potent Cholesteryl Ester Transfer Protein (CETP) Inhibitor, in Healthy Subjects. Clin Pharmacol Ther 2008; 84(6): 679-83.
    • (2008) Clin Pharmacol Ther , vol.84 , Issue.6 , pp. 679-683
    • Krishna, R.1    Bergman, A.2    Jin, B.3
  • 212
    • 48149106322 scopus 로고    scopus 로고
    • Torcetrapib-induced blood pressure elevation is independent of CETP inhibition and is accompanied by increased circulating levels of aldosterone
    • Forrest MJ, Bloomfield D, Briscoe RJ, et al. Torcetrapib-induced blood pressure elevation is independent of CETP inhibition and is accompanied by increased circulating levels of aldosterone. Br J Pharmacol 2008; 154: 1465-73.
    • (2008) Br J Pharmacol , vol.154 , pp. 1465-1473
    • Forrest, M.J.1    Bloomfield, D.2    Briscoe, R.J.3
  • 213
    • 52949140241 scopus 로고    scopus 로고
    • JTT-705: Is there still future for a CETP inhibitor after torcetrapib?
    • Rennings AJ, Stalenhoef AF. JTT-705: is there still future for a CETP inhibitor after torcetrapib? Expert Opin Investig Drugs 2008; 17: 1589-97.
    • (2008) Expert Opin Investig Drugs , vol.17 , pp. 1589-1597
    • Rennings, A.J.1    Stalenhoef, A.F.2
  • 214
    • 57849131140 scopus 로고    scopus 로고
    • Cholesterylestertransfer Protein inhibition and endothelial function in type II hyperlipidemia
    • Hermann F, Enseleit F, Spieker LE, et al. Cholesterylestertransfer Protein inhibition and endothelial function in type II hyperlipidemia. Thromb Res 2009; 123(3): 460-5.
    • (2009) Thromb Res , vol.123 , Issue.3 , pp. 460-465
    • Hermann, F.1    Enseleit, F.2    Spieker, L.E.3
  • 215
    • 67651154314 scopus 로고    scopus 로고
    • The end of the road for CETP inhibitors after torcetrapib?
    • Joy T, Hegele RA. The end of the road for CETP inhibitors after torcetrapib? Curr Opin Cardiol 2009; 24: 364-71.
    • (2009) Curr Opin Cardiol , vol.24 , pp. 364-371
    • Joy, T.1    Hegele, R.A.2
  • 216
    • 0242577955 scopus 로고    scopus 로고
    • Effect of recombinant ApoA-I Milano on coronary atherosclerosis in patients with acute coronary syndromes: A randomized controlled trial
    • Nissen SE, Tsunoda T, Tuzcu EM, et al. Effect of recombinant ApoA-I Milano on coronary atherosclerosis in patients with acute coronary syndromes: a randomized controlled trial. JAMA 2003; 290: 2292-300.
    • (2003) JAMA , vol.290 , pp. 2292-2300
    • Nissen, S.E.1    Tsunoda, T.2    Tuzcu, E.M.3
  • 217
    • 3042598045 scopus 로고    scopus 로고
    • Focus on high-density lipoproteins in reducing cardiovascular risk
    • Brewer HB, Jr. Focus on high-density lipoproteins in reducing cardiovascular risk. Am Heart J 2004; 148: S14-8.
    • (2004) Am Heart J , vol.148
    • Brewer Jr., H.B.1
  • 219
    • 34249106358 scopus 로고    scopus 로고
    • Oral administration of the apolipoprotein A-1 mimetic peptide D-4F in humans with CHD improves HDL anti-inflammatory function after a single dose
    • Bloedon LT, Dunbar RL, Duffy D, et al. Oral administration of the apolipoprotein A-1 mimetic peptide D-4F in humans with CHD improves HDL anti-inflammatory function after a single dose. Circulation 2006; 114: 288.
    • (2006) Circulation , vol.114 , pp. 288
    • Bloedon, L.T.1    Dunbar, R.L.2    Duffy, D.3
  • 220
    • 0027994776 scopus 로고
    • Recombinant apolipoprotein A-I Milano reduces intimal thickening after balloon injury in hypercholesterolemic rabbits
    • Ameli S, Hultgardh-Nilsson A, Cercek B, et al. Recombinant apolipoprotein A-I Milano reduces intimal thickening after balloon injury in hypercholesterolemic rabbits. Circulation 1994; 90: 1935-41.
    • (1994) Circulation , vol.90 , pp. 1935-1941
    • Ameli, S.1    Hultgardh-Nilsson, A.2    Cercek, B.3
  • 221
    • 0028985103 scopus 로고
    • Recombinant apolipoprotein A-IMilano dimer inhibits carotid intimal thickening induced by perivascular manipulation in rabbits
    • Soma MR, Donetti E, Parolini C, et al. Recombinant apolipoprotein A-IMilano dimer inhibits carotid intimal thickening induced by perivascular manipulation in rabbits. Circ Res 1995; 76: 405-11.
    • (1995) Circ Res , vol.76 , pp. 405-411
    • Soma, M.R.1    Donetti, E.2    Parolini, C.3
  • 222
    • 0032478183 scopus 로고    scopus 로고
    • Effects of recombinant apolipoprotein A-I(Milano) on aortic atherosclerosis in apolipoprotein Edeficient mice
    • Shah PK, Nilsson J, Kaul S, et al. Effects of recombinant apolipoprotein A-I(Milano) on aortic atherosclerosis in apolipoprotein Edeficient mice. Circulation 1998; 97: 780-5.
    • (1998) Circulation , vol.97 , pp. 780-785
    • Shah, P.K.1    Nilsson, J.2    Kaul, S.3
  • 223
    • 0037124010 scopus 로고    scopus 로고
    • Recombinant apolipoprotein A-I(Milano) infusion into rabbit carotid artery rapidly removes lipid from fatty streaks
    • Chiesa G, Monteggia E, Marchesi M, et al. Recombinant apolipoprotein A-I(Milano) infusion into rabbit carotid artery rapidly removes lipid from fatty streaks. Circ Res 2002; 90: 974-80.
    • (2002) Circ Res , vol.90 , pp. 974-980
    • Chiesa, G.1    Monteggia, E.2    Marchesi, M.3
  • 224
    • 40649126377 scopus 로고    scopus 로고
    • Dose-related effects of repeated ETC-216 (recombinant apolipoprotein A-I Milano/1- palmitoyl-2-oleoyl phosphatidylcholine complexes) administrations on rabbit lipid-rich soft plaques: In vivo assessment by intravascular ultrasound and magnetic resonance imaging
    • Parolini C, Marchesi M, Lorenzon P, et al. Dose-related effects of repeated ETC-216 (recombinant apolipoprotein A-I Milano/1- palmitoyl-2-oleoyl phosphatidylcholine complexes) administrations on rabbit lipid-rich soft plaques: in vivo assessment by intravascular ultrasound and magnetic resonance imaging. J Am Coll Cardiol 2008; 51: 1098-103.
    • (2008) J Am Coll Cardiol , vol.51 , pp. 1098-1103
    • Parolini, C.1    Marchesi, M.2    Lorenzon, P.3
  • 225
    • 34247397359 scopus 로고    scopus 로고
    • Effects of reconstituted high-density lipoprotein infusions on coronary atherosclerosis: A randomized controlled trial
    • Tardif JC, Gregoire J, L'Allier PL, et al. Effects of reconstituted high-density lipoprotein infusions on coronary atherosclerosis: a randomized controlled trial. JAMA 2007; 297: 1675-82.
    • (2007) JAMA , vol.297 , pp. 1675-1682
    • Tardif, J.C.1    Gregoire, J.2    L'Allier, P.L.3
  • 226
    • 0037065730 scopus 로고    scopus 로고
    • Apolipoprotein A-I(Milano) and apolipoprotein A-I(Paris) exhibit an antioxidant activity distinct from that of wild-type apolipoprotein A-I
    • Bielicki JK, Oda MN. Apolipoprotein A-I(Milano) and apolipoprotein A-I(Paris) exhibit an antioxidant activity distinct from that of wild-type apolipoprotein A-I. Biochemistry 2002; 41: 2089-96.
    • (2002) Biochemistry , vol.41 , pp. 2089-2096
    • Bielicki, J.K.1    Oda, M.N.2
  • 227
    • 35848948176 scopus 로고    scopus 로고
    • Normal vascular function despite low levels of high-density lipoprotein cholesterol in carriers of the apolipoprotein A-I(Milano) mutant
    • Gomaraschi M, Baldassarre D, Amato M, et al. Normal vascular function despite low levels of high-density lipoprotein cholesterol in carriers of the apolipoprotein A-I(Milano) mutant. Circulation 2007; 116: 2165-72.
    • (2007) Circulation , vol.116 , pp. 2165-2172
    • Gomaraschi, M.1    Baldassarre, D.2    Amato, M.3
  • 228
    • 0038311032 scopus 로고    scopus 로고
    • Restoration of endothelial function by increasing high-density lipoprotein in subjects with isolated low high-density lipoprotein
    • Bisoendial RJ, Hovingh GK, Levels JH, et al. Restoration of endothelial function by increasing high-density lipoprotein in subjects with isolated low high-density lipoprotein. Circulation 2003; 107: 2944-8.
    • (2003) Circulation , vol.107 , pp. 2944-2948
    • Bisoendial, R.J.1    Hovingh, G.K.2    Levels, J.H.3
  • 229
    • 0037154287 scopus 로고    scopus 로고
    • Oral administration of an Apo A-I mimetic Peptide synthesized from D-amino acids dramatically reduces atherosclerosis in mice independent of plasma cholesterol
    • Navab M, Anantharamaiah GM, Hama S, et al. Oral administration of an Apo A-I mimetic Peptide synthesized from D-amino acids dramatically reduces atherosclerosis in mice independent of plasma cholesterol. Circulation 2002; 105: 290-2.
    • (2002) Circulation , vol.105 , pp. 290-292
    • Navab, M.1    Anantharamaiah, G.M.2    Hama, S.3
  • 230
    • 4544383898 scopus 로고    scopus 로고
    • Oral D-4F causes formation of pre-beta high-density lipoprotein and improves highdensity lipoprotein-mediated cholesterol efflux and reverse cholesterol transport from macrophages in apolipoprotein E-null mice
    • Navab M, Anantharamaiah GM, Reddy ST, et al. Oral D-4F causes formation of pre-beta high-density lipoprotein and improves highdensity lipoprotein-mediated cholesterol efflux and reverse cholesterol transport from macrophages in apolipoprotein E-null mice. Circulation 2004; 109: 3215-20.
    • (2004) Circulation , vol.109 , pp. 3215-3220
    • Navab, M.1    Anantharamaiah, G.M.2    Reddy, S.T.3
  • 231
    • 21544482554 scopus 로고    scopus 로고
    • D-4F and statins synergize to render HDL antiinflammatory in mice and monkeys and cause lesion regression in old apolipoprotein E-null mice
    • Navab M, Anantharamaiah GM, Hama S, et al. D-4F and statins synergize to render HDL antiinflammatory in mice and monkeys and cause lesion regression in old apolipoprotein E-null mice. Arterioscler Thromb Vasc Biol 2005; 25: 1426-32.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 1426-1432
    • Navab, M.1    Anantharamaiah, G.M.2    Hama, S.3
  • 232
    • 35848961212 scopus 로고    scopus 로고
    • Lipoprotein inflammatory properties and serum amyloid A levels but not cholesterol levels predict lesion area in cholesterol-fed rabbits
    • Van Lenten BJ, Wagner AC, Navab M, et al. Lipoprotein inflammatory properties and serum amyloid A levels but not cholesterol levels predict lesion area in cholesterol-fed rabbits. J Lipid Res 2007; 48: 2344-53.
    • (2007) J Lipid Res , vol.48 , pp. 2344-2353
    • Van Lenten, B.J.1    Wagner, A.C.2    Navab, M.3
  • 233
    • 25444520268 scopus 로고    scopus 로고
    • Oral small peptides render HDL antiinflammatory in mice and monkeys and reduce atherosclerosis in ApoE null mice
    • Navab M, Anantharamaiah GM, Reddy ST, et al. Oral small peptides render HDL antiinflammatory in mice and monkeys and reduce atherosclerosis in ApoE null mice. Circ Res 2005; 97: 524-32.
    • (2005) Circ Res , vol.97 , pp. 524-532
    • Navab, M.1    Anantharamaiah, G.M.2    Reddy, S.T.3
  • 234
    • 14444285707 scopus 로고    scopus 로고
    • Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway
    • Lehmann JM, Kliewer SA, Moore LB, et al. Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway. J Biol Chem 1997; 272: 3137-40.
    • (1997) J Biol Chem , vol.272 , pp. 3137-3140
    • Lehmann, J.M.1    Kliewer, S.A.2    Moore, L.B.3
  • 235
    • 0034284918 scopus 로고    scopus 로고
    • Regulation of absorption and ABC1-mediated efflux of cholesterol by RXR heterodimers
    • Repa JJ, Turley SD, Lobaccaro JA, et al. Regulation of absorption and ABC1-mediated efflux of cholesterol by RXR heterodimers. Science 2000; 289: 1524-9.
    • (2000) Science , vol.289 , pp. 1524-1529
    • Repa, J.J.1    Turley, S.D.2    Lobaccaro, J.A.3
  • 236
    • 0037166261 scopus 로고    scopus 로고
    • Regulation of ATP-binding cassette sterol transporters ABCG5 and ABCG8 by the liver X receptors alpha and beta
    • Repa JJ, Berge KE, Pomajzl C, et al. Regulation of ATP-binding cassette sterol transporters ABCG5 and ABCG8 by the liver X receptors alpha and beta. J Biol Chem 2002; 277: 18793-800.
    • (2002) J Biol Chem , vol.277 , pp. 18793-18800
    • Repa, J.J.1    Berge, K.E.2    Pomajzl, C.3
  • 237
    • 0034623288 scopus 로고    scopus 로고
    • Sterol-dependent transactivation of the ABC1 promoter by the liver X receptor/retinoid X receptor
    • Costet P, Luo Y, Wang N, Tall AR. Sterol-dependent transactivation of the ABC1 promoter by the liver X receptor/retinoid X receptor. J Biol Chem 2000; 275: 28240-5.
    • (2000) J Biol Chem , vol.275 , pp. 28240-28245
    • Costet, P.1    Luo, Y.2    Wang, N.3    Tall, A.R.4
  • 238
    • 0037044830 scopus 로고    scopus 로고
    • Mice expressing the human CYP7A1 gene in the mouse CYP7A1 knock-out background lack induction of CYP7A1 expression by cholesterol feeding and have increased hypercholesterolemia when fed a high fat diet
    • Chen JY, Levy-Wilson B, Goodart S, Cooper AD. Mice expressing the human CYP7A1 gene in the mouse CYP7A1 knock-out background lack induction of CYP7A1 expression by cholesterol feeding and have increased hypercholesterolemia when fed a high fat diet. J Biol Chem 2002; 277: 42588-95.
    • (2002) J Biol Chem , vol.277 , pp. 42588-42595
    • Chen, J.Y.1    Levy-Wilson, B.2    Goodart, S.3    Cooper, A.D.4
  • 239
    • 33745029827 scopus 로고    scopus 로고
    • LXR-induced redistribution of ABCG1 to plasma membrane in macrophages enhances cholesterol mass efflux to HDL
    • Wang N, Ranalletta M, Matsuura F, et al. LXR-induced redistribution of ABCG1 to plasma membrane in macrophages enhances cholesterol mass efflux to HDL. Arterioscler Thromb Vasc Biol 2006; 26: 1310-6.
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , pp. 1310-1316
    • Wang, N.1    Ranalletta, M.2    Matsuura, F.3
  • 240
    • 33644651160 scopus 로고    scopus 로고
    • Liver X receptors as integrators of metabolic and inflammatory signaling
    • Zelcer N, Tontonoz P. Liver X receptors as integrators of metabolic and inflammatory signaling. J Clin Invest 2006; 116: 607-14.
    • (2006) J Clin Invest , vol.116 , pp. 607-614
    • Zelcer, N.1    Tontonoz, P.2
  • 241
    • 0037432165 scopus 로고    scopus 로고
    • T-0901317, a synthetic liver X receptor ligand, inhibits development of atherosclerosis in LDL receptor-deficient mice
    • Terasaka N, Hiroshima A, Koieyama T, et al. T-0901317, a synthetic liver X receptor ligand, inhibits development of atherosclerosis in LDL receptor-deficient mice. FEBS Lett 2003; 536: 6-11.
    • (2003) FEBS Lett , vol.536 , pp. 6-11
    • Terasaka, N.1    Hiroshima, A.2    Koieyama, T.3
  • 242
    • 0037188553 scopus 로고    scopus 로고
    • Synthetic LXR ligand inhibits the development of atherosclerosis in mice
    • Joseph SB, McKilligin E, Pei L et al. Synthetic LXR ligand inhibits the development of atherosclerosis in mice. Proc Natl Acad Sci USA 2002; 99: 7604-9.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 7604-7609
    • Joseph, S.B.1    McKilligin, E.2    Pei, L.3
  • 243
    • 11144230882 scopus 로고    scopus 로고
    • Macrophage liver X receptor is required for antiatherogenic activity of LXR agonists
    • Levin N, Bischoff ED, Daige CL, et al. Macrophage liver X receptor is required for antiatherogenic activity of LXR agonists. Arterioscler Thromb Vasc Biol 2005; 25: 135-42.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 135-142
    • Levin, N.1    Bischoff, E.D.2    Daige, C.L.3
  • 244
    • 11144257009 scopus 로고    scopus 로고
    • Increased fecal neutral sterol loss upon liver X receptor activation is independent of biliary sterol secretion in mice
    • Kruit JK, Plosch T, Havinga R, et al. Increased fecal neutral sterol loss upon liver X receptor activation is independent of biliary sterol secretion in mice. Gastroenterology 2005; 128: 147-56.
    • (2005) Gastroenterology , vol.128 , pp. 147-156
    • Kruit, J.K.1    Plosch, T.2    Havinga, R.3
  • 245
    • 67749110331 scopus 로고    scopus 로고
    • Activation of the liver X receptor stimulates trans-intestinal excretion of plasma cholesterol
    • van der Veen JN, van Dijk TH, Vrins CL, et al. Activation of the liver X receptor stimulates trans-intestinal excretion of plasma cholesterol. J Biol Chem 2009; 284: 19211-9.
    • (2009) J Biol Chem , vol.284 , pp. 19211-19219
    • van der Veen, J.N.1    van Dijk, T.H.2    Vrins, C.L.3
  • 246
    • 34548492458 scopus 로고    scopus 로고
    • Direct intestinal cholesterol secretion contributes significantly to total fecal neutral sterol excretion in mice
    • van der Velde AE, Vrins CL, van den Oever K, et al. Direct intestinal cholesterol secretion contributes significantly to total fecal neutral sterol excretion in mice. Gastroenterology 2007; 133: 967-75.
    • (2007) Gastroenterology , vol.133 , pp. 967-975
    • van der Velde, A.E.1    Vrins, C.L.2    van den Oever, K.3
  • 248
    • 36348998164 scopus 로고    scopus 로고
    • The liver X receptor and atherosclerosis
    • Scott J. The liver X receptor and atherosclerosis. N Engl J Med 2007; 357: 2195-7.
    • (2007) N Engl J Med , vol.357 , pp. 2195-2197
    • Scott, J.1
  • 249
    • 0032816777 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-alpha activators regulate genes governing lipoprotein metabolism, vascular inflammation and atherosclerosis
    • Fruchart JC, Duriez P, Staels B. Peroxisome proliferator-activated receptor-alpha activators regulate genes governing lipoprotein metabolism, vascular inflammation and atherosclerosis. Curr Opin Lipidol 1999; 10: 245-57.
    • (1999) Curr Opin Lipidol , vol.10 , pp. 245-257
    • Fruchart, J.C.1    Duriez, P.2    Staels, B.3
  • 250
    • 34250212715 scopus 로고    scopus 로고
    • Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes
    • Nissen SE, Wolski K. Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes. N Engl J Med 2007; 356: 2457-71.
    • (2007) N Engl J Med , vol.356 , pp. 2457-2471
    • Nissen, S.E.1    Wolski, K.2
  • 251
    • 41649084422 scopus 로고    scopus 로고
    • Comparison of pioglitazone vs. glimepiride on progression of coronary atherosclerosis in patients with type 2 diabetes: The PERISCOPE randomized controlled trial
    • Nissen SE, Nicholls SJ, Wolski K, et al. Comparison of pioglitazone vs. glimepiride on progression of coronary atherosclerosis in patients with type 2 diabetes: the PERISCOPE randomized controlled trial. JAMA 2008; 299: 1561-73.
    • (2008) JAMA , vol.299 , pp. 1561-1573
    • Nissen, S.E.1    Nicholls, S.J.2    Wolski, K.3
  • 252
    • 8944252340 scopus 로고    scopus 로고
    • Opposite regulation of human vs. mouse apolipoprotein A-I by fibrates in human apolipoprotein A-I transgenic mice
    • Berthou L, Duverger N, Emmanuel F, et al. Opposite regulation of human vs. mouse apolipoprotein A-I by fibrates in human apolipoprotein A-I transgenic mice. J Clin Invest 1996; 97: 2408-16.
    • (1996) J Clin Invest , vol.97 , pp. 2408-2416
    • Berthou, L.1    Duverger, N.2    Emmanuel, F.3
  • 253
    • 20044396568 scopus 로고    scopus 로고
    • Regulation of human apoA-I by gemfibrozil and fenofibrate through selective peroxisome proliferator- activated receptor alpha modulation
    • Duez H, Lefebvre B, Poulain P, et al. Regulation of human apoA-I by gemfibrozil and fenofibrate through selective peroxisome proliferator- activated receptor alpha modulation. Arterioscler Thromb Vasc Biol 2005; 25: 585-91.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 585-591
    • Duez, H.1    Lefebvre, B.2    Poulain, P.3
  • 254
    • 0035138625 scopus 로고    scopus 로고
    • PPAR-alpha and PPARgamma activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway
    • Chinetti G, Lestavel S, Bocher V, et al. PPAR-alpha and PPARgamma activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway. Nat Med 2001; 7: 53-8.
    • (2001) Nat Med , vol.7 , pp. 53-58
    • Chinetti, G.1    Lestavel, S.2    Bocher, V.3
  • 255
    • 85047693466 scopus 로고    scopus 로고
    • Differential inhibition of macrophage foam-cell formation and atherosclerosis in mice by PPARalpha, beta/delta, and gamma
    • Li AC, Binder CJ, Gutierrez A, et al. Differential inhibition of macrophage foam-cell formation and atherosclerosis in mice by PPARalpha, beta/delta, and gamma. J Clin Invest 2004; 114: 1564-76.
    • (2004) J Clin Invest , vol.114 , pp. 1564-1576
    • Li, A.C.1    Binder, C.J.2    Gutierrez, A.3
  • 256
    • 78650546846 scopus 로고    scopus 로고
    • Differential effects of gemfibrozil and fenofibrate on reverse cholesterol transport from macrophages to feces in vivo
    • doi:10.1016/j.bbalip.2010.11.006
    • Rotllan N, Llaverías G, Julve J, et al. Differential effects of gemfibrozil and fenofibrate on reverse cholesterol transport from macrophages to feces in vivo. Biochim Biophys Acta 2010 doi:10.1016/j.bbalip.2010.11.006.
    • (2010) Biochim Biophys Acta
    • Rotllan, N.1    Llaverías, G.2    Julve, J.3
  • 257
    • 2242436246 scopus 로고    scopus 로고
    • Reduction of atherosclerosis by the peroxisome proliferator-activated receptor alpha agonist fenofibrate in mice
    • Duez H, Chao YS, Hernandez M, et al. Reduction of atherosclerosis by the peroxisome proliferator-activated receptor alpha agonist fenofibrate in mice. J Biol Chem 2002; 277: 48051-7.
    • (2002) J Biol Chem , vol.277 , pp. 48051-48057
    • Duez, H.1    Chao, Y.S.2    Hernandez, M.3
  • 258
    • 33846443997 scopus 로고    scopus 로고
    • Triglyceride: Highdensity lipoprotein cholesterol effects in healthy subjects administered a peroxisome proliferator activated receptor delta agonist
    • Sprecher DL, Massien C, Pearce G, et al. Triglyceride: highdensity lipoprotein cholesterol effects in healthy subjects administered a peroxisome proliferator activated receptor delta agonist. Arterioscler Thromb Vasc Biol 2007; 27: 359-65.
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , pp. 359-365
    • Sprecher, D.L.1    Massien, C.2    Pearce, G.3
  • 259
    • 0034685589 scopus 로고    scopus 로고
    • Activation of PPARdelta alters lipid metabolism in db/db mice
    • Leibowitz MD, Fievet C, Hennuyer N, et al. Activation of PPARdelta alters lipid metabolism in db/db mice. FEBS Lett 2000; 473: 333-6.
    • (2000) FEBS Lett , vol.473 , pp. 333-336
    • Leibowitz, M.D.1    Fievet, C.2    Hennuyer, N.3
  • 260
    • 0035942162 scopus 로고    scopus 로고
    • A selective peroxisome proliferator-activated receptor delta agonist promotes reverse cholesterol transport
    • Oliver WR, Jr., Shenk JL, Snaith MR, et al. A selective peroxisome proliferator-activated receptor delta agonist promotes reverse cholesterol transport. Proc Natl Acad Sci USA 2001; 98: 5306-11.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 5306-5311
    • Oliver Jr., W.R.1    Shenk, J.L.2    Snaith, M.R.3
  • 261
    • 20444378931 scopus 로고    scopus 로고
    • The PPARdelta agonist GW0742X reduces atherosclerosis in LDLR(-/-) mice
    • Graham TL, Mookherjee C, Suckling KE, et al. The PPARdelta agonist GW0742X reduces atherosclerosis in LDLR(-/-) mice. Atherosclerosis 2005; 181: 29-37.
    • (2005) Atherosclerosis , vol.181 , pp. 29-37
    • Graham, T.L.1    Mookherjee, C.2    Suckling, K.E.3
  • 262
    • 41949138804 scopus 로고    scopus 로고
    • PPARdelta regulates multiple proinflammatory pathways to suppress atherosclerosis
    • Barish GD, Atkins AR, Downes M, et al. PPARdelta regulates multiple proinflammatory pathways to suppress atherosclerosis. Proc Natl Acad Sci USA 2008; 105: 4271-6.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 4271-4276
    • Barish, G.D.1    Atkins, A.R.2    Downes, M.3
  • 263
    • 0037044454 scopus 로고    scopus 로고
    • Inhibition of intestinal cholesterol absorption by ezetimibe in humans
    • Sudhop T, Lutjohann D, Kodal A, et al. Inhibition of intestinal cholesterol absorption by ezetimibe in humans. Circulation 2002; 106: 1943-8.
    • (2002) Circulation , vol.106 , pp. 1943-1948
    • Sudhop, T.1    Lutjohann, D.2    Kodal, A.3
  • 264
    • 0038546821 scopus 로고    scopus 로고
    • Cholesterol absorption inhibitors: Defining new options in lipid management
    • Brown WV. Cholesterol absorption inhibitors: defining new options in lipid management. Clin Cardiol 2003; 26: 259-64.
    • (2003) Clin Cardiol , vol.26 , pp. 259-264
    • Brown, W.V.1
  • 265
    • 52649138998 scopus 로고    scopus 로고
    • Analyses of cancer data from three ezetimibe trials
    • Peto R, Emberson J, Landray M, et al. Analyses of cancer data from three ezetimibe trials. N Engl J Med 2008; 359: 1357-66.
    • (2008) N Engl J Med , vol.359 , pp. 1357-1366
    • Peto, R.1    Emberson, J.2    Landray, M.3
  • 266
    • 41649090426 scopus 로고    scopus 로고
    • Effect of rimonabant on progression of atherosclerosis in patients with abdominal obesity and coronary artery disease: The STRADIVARIUS randomized controlled trial
    • Nissen SE, Nicholls SJ, Wolski K, et al. Effect of rimonabant on progression of atherosclerosis in patients with abdominal obesity and coronary artery disease: the STRADIVARIUS randomized controlled trial. JAMA 2008; 299: 1547-60.
    • (2008) JAMA , vol.299 , pp. 1547-1560
    • Nissen, S.E.1    Nicholls, S.J.2    Wolski, K.3
  • 267
    • 0035572836 scopus 로고    scopus 로고
    • Ezetimibe, a potent cholesterol absorption inhibitor, inhibits the development of atherosclerosis in ApoE knockout mice
    • Davis HR, Jr., Compton DS, Hoos L, Tetzloff G. Ezetimibe, a potent cholesterol absorption inhibitor, inhibits the development of atherosclerosis in ApoE knockout mice. Arterioscler Thromb Vasc Biol 2001; 21: 2032-8.
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 2032-2038
    • Davis Jr., H.R.1    Compton, D.S.2    Hoos, L.3    Tetzloff, G.4
  • 268
    • 34247209263 scopus 로고    scopus 로고
    • Deficiency of Niemann- Pick C1 Like 1 prevents atherosclerosis in ApoE-/- mice
    • Davis HR, Jr., Hoos LM, Tetzloff G, et al. Deficiency of Niemann- Pick C1 Like 1 prevents atherosclerosis in ApoE-/- mice. Arterioscler Thromb Vasc Biol 2007; 27: 841-9.
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , pp. 841-849
    • Davis Jr., H.R.1    Hoos, L.M.2    Tetzloff, G.3
  • 269
    • 20444371945 scopus 로고    scopus 로고
    • The target of ezetimibe is Niemann-Pick C1-Like 1 (NPC1L1)
    • Garcia-Calvo M, Lisnock J, Bull HG, et al. The target of ezetimibe is Niemann-Pick C1-Like 1 (NPC1L1). Proc Natl Acad Sci USA 2005; 102: 8132-7.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 8132-8137
    • Garcia-Calvo, M.1    Lisnock, J.2    Bull, H.G.3
  • 270
    • 46249110108 scopus 로고    scopus 로고
    • Cholesterol absorption from the intestine is a major determinant of reverse cholesterol transport from peripheral tissue macrophages
    • Sehayek E, Hazen SL. Cholesterol absorption from the intestine is a major determinant of reverse cholesterol transport from peripheral tissue macrophages. Arterioscler Thromb Vasc Biol 2008; 28: 1296-7.
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , pp. 1296-1297
    • Sehayek, E.1    Hazen, S.L.2
  • 271
    • 41649107358 scopus 로고    scopus 로고
    • Simvastatin with or without ezetimibe in familial hypercholesterolemia
    • Kastelein JJ, Akdim F, Stroes ES, et al. Simvastatin with or without ezetimibe in familial hypercholesterolemia. N Engl J Med 2008; 358: 1431-43.
    • (2008) N Engl J Med , vol.358 , pp. 1431-1443
    • Kastelein, J.J.1    Akdim, F.2    Stroes, E.S.3
  • 272
    • 73949102609 scopus 로고    scopus 로고
    • Moderately decreased cholesterol absorption rates are associated with a large atheroprotective effect
    • Greenberg ME, Smith JD, Sehayek E. Moderately decreased cholesterol absorption rates are associated with a large atheroprotective effect. Arterioscler Thromb Vasc Biol 2009; 29: 1745-50.
    • (2009) Arterioscler Thromb Vasc Biol , vol.29 , pp. 1745-1750
    • Greenberg, M.E.1    Smith, J.D.2    Sehayek, E.3
  • 273
    • 33746851173 scopus 로고    scopus 로고
    • Consumption of saturated fat impairs the anti-inflammatory properties of high-density lipoproteins and endothelial function
    • Nicholls SJ, Lundman P, Harmer JA, et al. Consumption of saturated fat impairs the anti-inflammatory properties of high-density lipoproteins and endothelial function. J Am Coll Cardiol 2006; 48: 715-20.
    • (2006) J Am Coll Cardiol , vol.48 , pp. 715-720
    • Nicholls, S.J.1    Lundman, P.2    Harmer, J.A.3
  • 274
    • 0038135048 scopus 로고    scopus 로고
    • Effects of dietary fatty acids and carbohydrates on the ratio of serum total to HDL cholesterol and on serum lipids and apolipoproteins: A metaanalysis of 60 controlled trials
    • Mensink RP, Zock PL, Kester AD, Katan MB. Effects of dietary fatty acids and carbohydrates on the ratio of serum total to HDL cholesterol and on serum lipids and apolipoproteins: a metaanalysis of 60 controlled trials. Am J Clin Nutr 2003; 77: 1146-55.
    • (2003) Am J Clin Nutr , vol.77 , pp. 1146-1155
    • Mensink, R.P.1    Zock, P.L.2    Kester, A.D.3    Katan, M.B.4
  • 275
    • 69749111974 scopus 로고    scopus 로고
    • The role of diet and nutritional supplements in preventing and treating cardiovascular disease
    • Hill AM, Fleming JA, Kris-Etherton PM. The role of diet and nutritional supplements in preventing and treating cardiovascular disease. Curr Opin Cardiol 2009; 24: 433-41.
    • (2009) Curr Opin Cardiol , vol.24 , pp. 433-441
    • Hill, A.M.1    Fleming, J.A.2    Kris-Etherton, P.M.3
  • 277
    • 0034088725 scopus 로고    scopus 로고
    • Effect of dietary omega-3 fatty acids and chronic ethanol consumption on reverse cholesterol transport in rats
    • Marmillot P, Rao MN, Liu QH, et al. Effect of dietary omega-3 fatty acids and chronic ethanol consumption on reverse cholesterol transport in rats. Metabolism 2000; 49: 508-12.
    • (2000) Metabolism , vol.49 , pp. 508-512
    • Marmillot, P.1    Rao, M.N.2    Liu, Q.H.3
  • 278
    • 0031677782 scopus 로고    scopus 로고
    • The -911/+25 sequence of human apolipoprotein A-II promoter is sufficient to confer liver restricted expression, developmental changes and response to a high fat diet in transgenic mice
    • Le Beyec J, Benetollo C, Chauffeton V et al. The -911/+25 sequence of human apolipoprotein A-II promoter is sufficient to confer liver restricted expression, developmental changes and response to a high fat diet in transgenic mice. Transgenics 1998; 2: 211-20.
    • (1998) Transgenics , vol.2 , pp. 211-220
    • Le Beyec, J.1    Benetollo, C.2    Chauffeton, V.3
  • 279
    • 0347357649 scopus 로고    scopus 로고
    • Fish oil increases antioxidant enzyme activities in macrophages and reduces atherosclerotic lesions in apoE-knockout mice
    • Wang HH, Hung TM, Wei J, Chiang AN. Fish oil increases antioxidant enzyme activities in macrophages and reduces atherosclerotic lesions in apoE-knockout mice. Cardiovasc Res 2004; 61: 169-76.
    • (2004) Cardiovasc Res , vol.61 , pp. 169-176
    • Wang, H.H.1    Hung, T.M.2    Wei, J.3    Chiang, A.N.4
  • 280
    • 56649114482 scopus 로고    scopus 로고
    • Atherosclerosis prevention by a fish oil-rich diet in apoE(-/-) mice is associated with a reduction of endothelial adhesion molecules
    • Casos K, Saiz MP, Ruiz-Sanz JI, Mitjavila MT. Atherosclerosis prevention by a fish oil-rich diet in apoE(-/-) mice is associated with a reduction of endothelial adhesion molecules. Atherosclerosis 2008; 201: 306-17.
    • (2008) Atherosclerosis , vol.201 , pp. 306-317
    • Casos, K.1    Saiz, M.P.2    Ruiz-Sanz, J.I.3    Mitjavila, M.T.4
  • 281
    • 0033071393 scopus 로고    scopus 로고
    • Concentration of serum lipids and aortic lesion size in female and male apo E-deficient mice fed docosahexaenoic acid
    • Adan Y, Shibata K, Ni W, et al. Concentration of serum lipids and aortic lesion size in female and male apo E-deficient mice fed docosahexaenoic acid. Biosci Biotechnol Biochem 1999; 63: 309-13.
    • (1999) Biosci Biotechnol Biochem , vol.63 , pp. 309-313
    • Adan, Y.1    Shibata, K.2    Ni, W.3
  • 282
    • 28344448270 scopus 로고    scopus 로고
    • Contrasting effect of fish oil supplementation on the development of atherosclerosis in murine models
    • Zampolli A, Bysted A, Leth T, et al. Contrasting effect of fish oil supplementation on the development of atherosclerosis in murine models. Atherosclerosis 2006; 184: 78-85.
    • (2006) Atherosclerosis , vol.184 , pp. 78-85
    • Zampolli, A.1    Bysted, A.2    Leth, T.3
  • 283
    • 0141528778 scopus 로고    scopus 로고
    • The J-shaped effect of coffee consumption on the risk of developing acute coronary syndromes: The CARDIO2000 case-control study
    • Panagiotakos DB, Pitsavos C, Chrysohoou C, et al. The J-shaped effect of coffee consumption on the risk of developing acute coronary syndromes: the CARDIO2000 case-control study. J Nutr 2003; 133: 3228-32.
    • (2003) J Nutr , vol.133 , pp. 3228-3232
    • Panagiotakos, D.B.1    Pitsavos, C.2    Chrysohoou, C.3
  • 284
    • 45549103018 scopus 로고    scopus 로고
    • The relationship of coffee consumption with mortality
    • Lopez-Garcia E, van Dam RM, Li TY, et al. The relationship of coffee consumption with mortality. Ann Intern Med 2008; 148: 904-14.
    • (2008) Ann Intern Med , vol.148 , pp. 904-914
    • Lopez-Garcia, E.1    van Dam, R.M.2    Li, T.Y.3
  • 286
    • 77949376766 scopus 로고    scopus 로고
    • Coffee consumption enhances high-density lipoprotein-mediated cholesterol efflux in macrophages
    • Uto-Kondo H, Ayaori M, Ogura M, et al. Coffee consumption enhances high-density lipoprotein-mediated cholesterol efflux in macrophages. Circ Res 2010; 106(4): 779-87.
    • (2010) Circ Res , vol.106 , Issue.4 , pp. 779-787
    • Uto-Kondo, H.1    Ayaori, M.2    Ogura, M.3
  • 287
    • 65549138006 scopus 로고    scopus 로고
    • Paraoxonases role in the prevention of cardiovascular diseases
    • Rosenblat M, Aviram M. Paraoxonases role in the prevention of cardiovascular diseases. Biofactors 2009; 35: 98-104.
    • (2009) Biofactors , vol.35 , pp. 98-104
    • Rosenblat, M.1    Aviram, M.2
  • 288
    • 39749145196 scopus 로고    scopus 로고
    • Translating molecular discoveries into new therapies for atherosclerosis
    • Rader DJ, Daugherty A. Translating molecular discoveries into new therapies for atherosclerosis. Nature 2008; 451: 904-13.
    • (2008) Nature , vol.451 , pp. 904-913
    • Rader, D.J.1    Daugherty, A.2
  • 291
    • 62649150750 scopus 로고    scopus 로고
    • Inflammation impairs reverse cholesterol transport in vivo
    • McGillicuddy FC, de la Llera Moya M, Hinkle CC, et al. Inflammation impairs reverse cholesterol transport in vivo. Circulation 2009; 119: 1135-45.
    • (2009) Circulation , vol.119 , pp. 1135-1145
    • McGillicuddy, F.C.1    de la Llera Moya, M.2    Hinkle, C.C.3
  • 292
    • 77950604454 scopus 로고    scopus 로고
    • Myeloperoxidase and serum amyloid A contribute to impaired in vivo reverse cholesterol transport during the acute phase response, but not group IIA secretory phospholipase A2
    • Annema W, Nijstad N, Tolle M, et al. Myeloperoxidase and serum amyloid A contribute to impaired in vivo reverse cholesterol transport during the acute phase response, but not group IIA secretory phospholipase A2. J Lipid Res 2010; 51: 743-54.
    • (2010) J Lipid Res , vol.51 , pp. 743-754
    • Annema, W.1    Nijstad, N.2    Tolle, M.3
  • 293
    • 0033051627 scopus 로고    scopus 로고
    • Chlamydia pneumoniae infection accelerates the progression of atherosclerosis in apolipoprotein E-deficient mice
    • Moazed TC, Campbell LA, Rosenfeld ME, et al. Chlamydia pneumoniae infection accelerates the progression of atherosclerosis in apolipoprotein E-deficient mice. J Infect Dis 1999; 180: 238-41.
    • (1999) J Infect Dis , vol.180 , pp. 238-241
    • Moazed, T.C.1    Campbell, L.A.2    Rosenfeld, M.E.3
  • 294
    • 0034516874 scopus 로고    scopus 로고
    • Chlamydia pneumoniae infection significantly exacerbates aortic atherosclerosis in an LDLR-/- mouse model within six months
    • Liu L, Hu H, Ji H, et al. Chlamydia pneumoniae infection significantly exacerbates aortic atherosclerosis in an LDLR-/- mouse model within six months. Mol Cell Biochem 2000; 215: 123-8.
    • (2000) Mol Cell Biochem , vol.215 , pp. 123-128
    • Liu, L.1    Hu, H.2    Ji, H.3
  • 295
    • 0036839433 scopus 로고    scopus 로고
    • Chlamydophila pneumoniae (Chlamydia pneumoniae) accelerates the formation of complex atherosclerotic lesions in Apo E3-Leiden mice
    • Ezzahiri R, Nelissen-Vrancken HJ, Kurvers HA, et al. Chlamydophila pneumoniae (Chlamydia pneumoniae) accelerates the formation of complex atherosclerotic lesions in Apo E3-Leiden mice. Cardiovasc Res 2002; 56: 269-76.
    • (2002) Cardiovasc Res , vol.56 , pp. 269-276
    • Ezzahiri, R.1    Nelissen-Vrancken, H.J.2    Kurvers, H.A.3
  • 296
    • 29144521809 scopus 로고    scopus 로고
    • Delivery of Chlamydia pneumoniae to the vessel wall aggravates atherosclerosis in LDLr- /- mice
    • Hauer AD, de Vos P, Peterse N, et al. Delivery of Chlamydia pneumoniae to the vessel wall aggravates atherosclerosis in LDLr- /- mice. Cardiovasc Res 2006; 69: 280-8.
    • (2006) Cardiovasc Res , vol.69 , pp. 280-288
    • Hauer, A.D.1    de Vos, P.2    Peterse, N.3
  • 297
    • 44949233003 scopus 로고    scopus 로고
    • Increased hepatic and circulating interleukin-6 levels in human non-alcoholic steatohepatitis
    • Wieckowska A, Papouchado BG, Li Z, et al. Increased hepatic and circulating interleukin-6 levels in human non-alcoholic steatohepatitis. Am J Gastroenterol 2008; 103: 1372-9.
    • (2008) Am J Gastroenterol , vol.103 , pp. 1372-1379
    • Wieckowska, A.1    Papouchado, B.G.2    Li, Z.3
  • 298
    • 11144237718 scopus 로고    scopus 로고
    • Association between elevated liver enzymes and C-reactive protein: Possible hepatic contribution to systemic inflammation in the metabolic syndrome
    • Kerner A, Avizohar O, Sella R, et al. Association between elevated liver enzymes and C-reactive protein: possible hepatic contribution to systemic inflammation in the metabolic syndrome. Arterioscler Thromb Vasc Biol 2005; 25: 193-7.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 193-197
    • Kerner, A.1    Avizohar, O.2    Sella, R.3
  • 299
    • 33746745255 scopus 로고    scopus 로고
    • Adiponectin and coronary heart disease: A prospective study and meta-analysis
    • Sattar N, Wannamethee G, Sarwar N, et al. Adiponectin and coronary heart disease: a prospective study and meta-analysis. Circulation 2006; 114: 623-9.
    • (2006) Circulation , vol.114 , pp. 623-629
    • Sattar, N.1    Wannamethee, G.2    Sarwar, N.3
  • 300
    • 0034005969 scopus 로고    scopus 로고
    • Hyperlipidemia and insulin resistance are induced by protease inhibitors independent of changes in body composition in patients with HIV infection
    • Mulligan K, Grunfeld C, Tai VW, et al. Hyperlipidemia and insulin resistance are induced by protease inhibitors independent of changes in body composition in patients with HIV infection. J Acquir Immune Defic Syndr 2000; 23: 35-43.
    • (2000) J Acquir Immune Defic Syndr , vol.23 , pp. 35-43
    • Mulligan, K.1    Grunfeld, C.2    Tai, V.W.3
  • 301
    • 0035824764 scopus 로고    scopus 로고
    • Nevirapinecontaining antiretroviral therapy in HIV-1 infected patients results in an anti-atherogenic lipid profile
    • van der Valk M, Kastelein JJ, Murphy RL, et al. Nevirapinecontaining antiretroviral therapy in HIV-1 infected patients results in an anti-atherogenic lipid profile. AIDS 2001; 15: 2407-14.
    • (2001) AIDS , vol.15 , pp. 2407-2414
    • van der Valk, M.1    Kastelein, J.J.2    Murphy, R.L.3
  • 302
    • 0037322240 scopus 로고    scopus 로고
    • Lipid profiles associated with antiretroviral drug choices
    • van der Valk M, Reiss P. Lipid profiles associated with antiretroviral drug choices. Curr Opin Infect Dis 2003; 16: 19-23.
    • (2003) Curr Opin Infect Dis , vol.16 , pp. 19-23
    • van der Valk, M.1    Reiss, P.2
  • 303
    • 67349213582 scopus 로고    scopus 로고
    • Effects of nevirapine and efavirenz on HDL cholesterol levels and reverse cholesterol transport in mice
    • Tohyama J, Billheimer JT, Fuki IV, et al. Effects of nevirapine and efavirenz on HDL cholesterol levels and reverse cholesterol transport in mice. Atherosclerosis 2009; 204: 418-23.
    • (2009) Atherosclerosis , vol.204 , pp. 418-423
    • Tohyama, J.1    Billheimer, J.T.2    Fuki, I.V.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.