Mice expressing the human CYP7A1 gene in the mouse CYP7A1 knock-out background lack induction of CYP7A1 expression by cholesterol feeding and have increased hypercholesterolemia when fed a high fat diet

Journal of Biological Chemistry

Volumn 277, Issue 45, 2002, Pages 42588-42595

  Chen, Jean Y ^a   Levy Wilson, Beatriz ^b   Goodart, Sheryl ^a   Cooper, Allen D ^a  

^a PALO ALTO MEDICAL FOUNDATION   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BODY FLUIDS; CATALYSIS; CHOLESTEROL; HORMONES; PROTEINS;

LIPOPROTEINS;

GENES;

BILE ACID; CELL NUCLEUS RECEPTOR; CHOLESTEROL; CHOLESTEROL 7ALPHA MONOOXYGENASE; CHOLIC ACID; COLESTYRAMINE; FARNESOID X RECEPTOR; FAT; HIGH DENSITY LIPOPROTEIN; HORMONE RECEPTOR; LIVER X RECEPTOR; LOW DENSITY LIPOPROTEIN; SATURATED FATTY ACID; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CATALYSIS; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; HOMOZYGOTE; HUMAN; HUMAN CELL; HYPERCHOLESTEROLEMIA; KNOCKOUT GENE; KNOCKOUT MOUSE; LIPID DIET; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; TRANSGENIC MOUSE; TRIACYLGLYCEROL BLOOD LEVEL;

ANIMALS; CHOLESTEROL 7-ALPHA-HYDROXYLASE; CHOLESTEROL, DIETARY; DIETARY FATS; ENZYME INDUCTION; FEMALE; HETEROZYGOTE; HOMOZYGOTE; HUMANS; HYPERCHOLESTEROLEMIA; LIVER; MALE; MICE; MICE, KNOCKOUT; RNA, MESSENGER; SEX CHARACTERISTICS; TIME FACTORS;

ANIMALIA; MUS MUSCULUS; RODENTIA;

EID: 0037044830     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M205117200     Document Type: Article

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