메뉴 건너뛰기




Volumn 97, Issue 11, 1996, Pages 2408-2416

Opposite regulation of human versus mouse apolipoprotein A-I by fibrates in human apolipoprotein A-I transgenic mice

Author keywords

atherosclerosis; gene regulation; HDL cholesterol; hypolipidemic drugs; peroxisome proliferation

Indexed keywords

ACYL COENZYME A OXIDASE; APOLIPOPROTEIN A1; CELL NUCLEUS RECEPTOR; DNA FRAGMENT; FENOFIBRATE; FENOFIBRIC ACID; FIBRIC ACID DERIVATIVE; GEMFIBROZIL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; MESSENGER RNA; PEROXISOME PROLIFERATOR;

EID: 8944252340     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI118687     Document Type: Article
Times cited : (248)

References (68)
  • 2
    • 0345146115 scopus 로고
    • Heterogeneity of high density lipoprotein particles
    • Fruchart, J.C., G. Ailhaud, and J.M. Bard. 1993. Heterogeneity of high density lipoprotein particles. Circulation. 87:22-27.
    • (1993) Circulation , vol.87 , pp. 22-27
    • Fruchart, J.C.1    Ailhaud, G.2    Bard, J.M.3
  • 3
    • 0028096796 scopus 로고
    • The role of apolipoprotein A-I-containing lipoproteins in atherosclerosis
    • Forte, T.M., and M.R. McCall. 1994. The role of apolipoprotein A-I-containing lipoproteins in atherosclerosis. Curr. Opin. Lipidol. 5:354-364.
    • (1994) Curr. Opin. Lipidol. , vol.5 , pp. 354-364
    • Forte, T.M.1    McCall, M.R.2
  • 4
    • 0025902231 scopus 로고
    • Inhibition of early atherogenesis in transgenic mice by human apolipoprotein Al
    • Rubin, E.M., R.M. Krauss, E.A. Spangler, J.G. Verstuyft, and S.M. Clift. 1991. Inhibition of early atherogenesis in transgenic mice by human apolipoprotein Al. Nature (Lond.). 353:265-267.
    • (1991) Nature (Lond.) , vol.353 , pp. 265-267
    • Rubin, E.M.1    Krauss, R.M.2    Spangler, E.A.3    Verstuyft, J.G.4    Clift, S.M.5
  • 5
    • 0023879854 scopus 로고
    • Effects of fibrates on serum lipids and atherosclerosis
    • Sirtori, C.R., and G. Franceschini. 1988. Effects of fibrates on serum lipids and atherosclerosis. Pharmacol. Ther. 37:167-191.
    • (1988) Pharmacol. Ther. , vol.37 , pp. 167-191
    • Sirtori, C.R.1    Franceschini, G.2
  • 6
    • 0025128458 scopus 로고
    • Fenofibrate, a review of its pharmacodynamic and pharmacokinetic properties and therapeutic use in dyslipidemia
    • Balfour, J.A., D. McTavish, and R.C. Heel. 1990. Fenofibrate, a review of its pharmacodynamic and pharmacokinetic properties and therapeutic use in dyslipidemia. Drugs. 40:260-290.
    • (1990) Drugs , vol.40 , pp. 260-290
    • Balfour, J.A.1    McTavish, D.2    Heel, R.C.3
  • 7
    • 0028817459 scopus 로고
    • Fibrates downregulate apolipoprotein C-III expression independent of induction of peroxisomal acyl coenzyme A oxidase
    • Staels, B., N. Vu-Dac, V.A. Kosykh, R. Saladin, J.C. Fruchart, J. Dallongeville, and J. Auwerx. 1995. Fibrates downregulate apolipoprotein C-III expression independent of induction of peroxisomal acyl coenzyme A oxidase. J. Clin. Invest. 95:705-712.
    • (1995) J. Clin. Invest. , vol.95 , pp. 705-712
    • Staels, B.1    Vu-Dac, N.2    Kosykh, V.A.3    Saladin, R.4    Fruchart, J.C.5    Dallongeville, J.6    Auwerx, J.7
  • 8
    • 0024245703 scopus 로고
    • Effects of ciprofibrate and fenofibrate on liver lipids and lipoprotein synthesis in normo- and hypercholesterolemic rats
    • Petit, D., M.T. Bonnefis, C. Rey, and R. Infante. 1988. Effects of ciprofibrate and fenofibrate on liver lipids and lipoprotein synthesis in normo- and hypercholesterolemic rats. Atherosclerosis. 74:215-225.
    • (1988) Atherosclerosis , vol.74 , pp. 215-225
    • Petit, D.1    Bonnefis, M.T.2    Rey, C.3    Infante, R.4
  • 10
    • 0026488464 scopus 로고
    • Perturbation of developmental gene expression in rat liver by fibric acid derivatives: Lipoprotein lipase and α-fetoprotein as models
    • Staels, B., and J. Auwerx. 1992. Perturbation of developmental gene expression in rat liver by fibric acid derivatives: lipoprotein lipase and α-fetoprotein as models. Development. 115:1035-1043.
    • (1992) Development , vol.115 , pp. 1035-1043
    • Staels, B.1    Auwerx, J.2
  • 11
    • 0024509605 scopus 로고
    • Biochemical mechanisms of induction of hepatic peroxisome proliferation
    • Lock, E.A., A.M. Michell, and C.R. Elcombe. 1989. Biochemical mechanisms of induction of hepatic peroxisome proliferation. Annu. Rev. Pharmacol. Toxicol. 29:145-163.
    • (1989) Annu. Rev. Pharmacol. Toxicol. , vol.29 , pp. 145-163
    • Lock, E.A.1    Michell, A.M.2    Elcombe, C.R.3
  • 14
    • 0342528190 scopus 로고
    • A fatty acyl-CoA oxidizing system in rat liver peroxisomes: Enhancement by clofibrate, a hypolipidemic drug
    • Lazarow, P., and C. de Duve. 1976. A fatty acyl-CoA oxidizing system in rat liver peroxisomes: enhancement by clofibrate, a hypolipidemic drug. Proc. Natl. Acad. Sci. USA. 73:2042-2046.
    • (1976) Proc. Natl. Acad. Sci. USA , vol.73 , pp. 2042-2046
    • Lazarow, P.1    De Duve, C.2
  • 15
    • 0026008055 scopus 로고
    • Characteristics of induction of peroxisomal fatty acid oxidation-related enzymes in rat liver by drugs
    • Kozuka, H., J. Yamada, S. Horie, T. Watanabe, T. Suga, and T. Ikeda. 1991. Characteristics of induction of peroxisomal fatty acid oxidation-related enzymes in rat liver by drugs. Biochem. Pharmacol. 41:617-623.
    • (1991) Biochem. Pharmacol. , vol.41 , pp. 617-623
    • Kozuka, H.1    Yamada, J.2    Horie, S.3    Watanabe, T.4    Suga, T.5    Ikeda, T.6
  • 16
    • 0025604385 scopus 로고
    • On the mechanism of induction of microsomal cytochrome P450IVA1 and peroxisome proliferation in rat liver by clofibrate
    • Milton, M.N., C.R. Elcombe, and G.G. Gibson. 1990. On the mechanism of induction of microsomal cytochrome P450IVA1 and peroxisome proliferation in rat liver by clofibrate. Biochem. Pharmacol. 40:2727-2732.
    • (1990) Biochem. Pharmacol. , vol.40 , pp. 2727-2732
    • Milton, M.N.1    Elcombe, C.R.2    Gibson, G.G.3
  • 17
    • 0025635882 scopus 로고
    • Induction of peroxisomal acyl CoA oxidase activity and lipid peroxidation in primary rat hepatocyte cultures
    • Tomaszewski, K.E., S.W. Heindel, W.L. Jenkins, and R.L. Melnick. 1990. Induction of peroxisomal acyl CoA oxidase activity and lipid peroxidation in primary rat hepatocyte cultures. Toxicology. 65:49-60.
    • (1990) Toxicology , vol.65 , pp. 49-60
    • Tomaszewski, K.E.1    Heindel, S.W.2    Jenkins, W.L.3    Melnick, R.L.4
  • 18
    • 0018888058 scopus 로고
    • Hypolipidaemic hepatic peroxisome proliferators from a new class of chemical carcinogens
    • Reddy, J.K., D.L. Azarnoff, and C.E. Hignite. 1980. Hypolipidaemic hepatic peroxisome proliferators from a new class of chemical carcinogens. Nature (Lond.). 283:397-398.
    • (1980) Nature (Lond.) , vol.283 , pp. 397-398
    • Reddy, J.K.1    Azarnoff, D.L.2    Hignite, C.E.3
  • 19
    • 0025132245 scopus 로고
    • Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators
    • Isseman, I., and S. Green. 1990. Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators. Nature (Lond.). 347:645-650.
    • (1990) Nature (Lond.) , vol.347 , pp. 645-650
    • Isseman, I.1    Green, S.2
  • 20
    • 0026541591 scopus 로고
    • The mouse peroxisome proliferator activated receptor recognizes a response element in the 5′ flanking sequence of the rat acyl CoA oxidase gene
    • Tugwood, J.D., I. Issemann, R.G. Anderson, K.R Bundell, W.L. McPheat, and S. Green. 1992. The mouse peroxisome proliferator activated receptor recognizes a response element in the 5′ flanking sequence of the rat acyl CoA oxidase gene. EMBO. (Eur. Mol. Biol. Organ.) J. 11:433-439.
    • (1992) EMBO. (Eur. Mol. Biol. Organ.) J. , vol.11 , pp. 433-439
    • Tugwood, J.D.1    Issemann, I.2    Anderson, R.G.3    Bundell, K.R.4    McPheat, W.L.5    Green, S.6
  • 21
    • 0026517010 scopus 로고
    • Control of the peroxisomal β-oxidation pathway by a novel family of nuclear hormone receptors
    • Dreyer, C., G. Krey, H. Keller, F. Givel, G. Helftenbein, and W. Wahli. 1992. Control of the peroxisomal β-oxidation pathway by a novel family of nuclear hormone receptors. Cell. 68:879-887.
    • (1992) Cell , vol.68 , pp. 879-887
    • Dreyer, C.1    Krey, G.2    Keller, H.3    Givel, F.4    Helftenbein, G.5    Wahli, W.6
  • 22
    • 0026976982 scopus 로고
    • Regulation of gene expression by fatty acids and fibric acid derivatives: An integrative role for peroxisome proliferator activated receptors
    • Auwerx, J. 1992. Regulation of gene expression by fatty acids and fibric acid derivatives: an integrative role for peroxisome proliferator activated receptors. Horm. Res. 38:269-277.
    • (1992) Horm. Res. , vol.38 , pp. 269-277
    • Auwerx, J.1
  • 23
    • 0027447461 scopus 로고
    • Fatty acids and retinoids control lipid metabolism through activation of peroxisome proliferator-activated receptor-retinoid X receptor heterodimers
    • Keller, H., C. Dreyer, J. Medin, A. Mahfoudi, K. Ozato, and W. Wahli. 1993. Fatty acids and retinoids control lipid metabolism through activation of peroxisome proliferator-activated receptor-retinoid X receptor heterodimers. Proc. Natl. Acad. Sci. USA. 90:2160-2164.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 2160-2164
    • Keller, H.1    Dreyer, C.2    Medin, J.3    Mahfoudi, A.4    Ozato, K.5    Wahli, W.6
  • 24
    • 0026577411 scopus 로고
    • Fibrates influence the expression of genes involved in lipoprotein metabolism in a tissue-selective manner in the rat
    • Staels, B., A. van Tol, T. Andreu, and J. Auwerx. 1992. Fibrates influence the expression of genes involved in lipoprotein metabolism in a tissue-selective manner in the rat. Arterioscler. Thromb. 12:286-294.
    • (1992) Arterioscler. Thromb. , vol.12 , pp. 286-294
    • Staels, B.1    Van Tol, A.2    Andreu, T.3    Auwerx, J.4
  • 26
    • 0021868786 scopus 로고
    • Effects of fenofibrate on high and low density lipoprotein metabolism in heterozygous familial hypercholesterolemia
    • Malmendier, C.L., and C. Delecroix. 1985. Effects of fenofibrate on high and low density lipoprotein metabolism in heterozygous familial hypercholesterolemia. Atherosclerosis. 55:161-169.
    • (1985) Atherosclerosis , vol.55 , pp. 161-169
    • Malmendier, C.L.1    Delecroix, C.2
  • 27
    • 0026631526 scopus 로고
    • A multicenter comparison of the effects of simvastatin and fenofibrate therapy in severe primary hypercholesterolemia, with particular emphasis on lipoproteins defined by their apolipoprotein composition
    • Bard, J.M., H.J. Parra, R. Camare, G. Luc, O. Ziegler, C. Dachet, E. Brueckert, P. Douste-Blazy, P. Drouin, B. Jacotot, J.L. De Gennes, U. Keller, and J.C. Fruchart. 1992. A multicenter comparison of the effects of simvastatin and fenofibrate therapy in severe primary hypercholesterolemia, with particular emphasis on lipoproteins defined by their apolipoprotein composition. Metabolism. 41:498-503.
    • (1992) Metabolism , vol.41 , pp. 498-503
    • Bard, J.M.1    Parra, H.J.2    Camare, R.3    Luc, G.4    Ziegler, O.5    Dachet, C.6    Brueckert, E.7    Douste-Blazy, P.8    Drouin, P.9    Jacotot, B.10    De Gennes, J.L.11    Keller, U.12    Fruchart, J.C.13
  • 28
    • 0020564469 scopus 로고
    • Clinical results with gemfibrozil and background to the Helsinki Heart Study
    • Manninen, V. 1983. Clinical results with gemfibrozil and background to the Helsinki Heart Study. Am. J. Cardiol. 52:35B-38B.
    • (1983) Am. J. Cardiol. , vol.52
    • Manninen, V.1
  • 29
    • 0022538038 scopus 로고
    • Effect of gemfibrozil on lipids, apoproteins, and postheparin lipolytic activities in normolipidemic subjects
    • Gnasso, A., B. Lehner, W. Haberbosch, O. Leiss, K. von Bergmann, and J. Augustin. 1986. Effect of gemfibrozil on lipids, apoproteins, and postheparin lipolytic activities in normolipidemic subjects. Metabolism. 35:387-393.
    • (1986) Metabolism , vol.35 , pp. 387-393
    • Gnasso, A.1    Lehner, B.2    Haberbosch, W.3    Leiss, O.4    Von Bergmann, K.5    Augustin, J.6
  • 31
    • 0026057848 scopus 로고
    • Expression of human apolipoprotein A-I in transgenic mice results in reduced plasma levels of murine apolipoprotein A-I and the appearance of two new high density lipoprotein size subclasses
    • Rubin, E.D., B.Y. Ishida, S.M. Clift, and R.M. Krauss. 1991. Expression of human apolipoprotein A-I in transgenic mice results in reduced plasma levels of murine apolipoprotein A-I and the appearance of two new high density lipoprotein size subclasses. Proc. Natl. Acad Sci. USA. 88:434-438.
    • (1991) Proc. Natl. Acad Sci. USA , vol.88 , pp. 434-438
    • Rubin, E.D.1    Ishida, B.Y.2    Clift, S.M.3    Krauss, R.M.4
  • 32
    • 0003054992 scopus 로고
    • Methods for preparation of adult and fetal hepatocyles
    • (Les edition INSERM and John Libbey, Euro text.) A. Guillouzo and C. Gugen-Guillouzo, editors. Les Editions ISERM and John Libbey Euro Text. Paris
    • Gugen-Guillouzo, C., and A. Guillouzo. 1986. Methods for preparation of adult and fetal hepatocyles. In Isolated and Cultured Hepatocytes (Les edition INSERM and John Libbey, Euro text.) A. Guillouzo and C. Gugen-Guillouzo, editors. Les Editions ISERM and John Libbey Euro Text. Paris. 1-12.
    • (1986) Isolated and Cultured Hepatocytes , pp. 1-12
    • Gugen-Guillouzo, C.1    Guillouzo, A.2
  • 33
    • 0010623223 scopus 로고
    • Apolipoproteins
    • H.U. Bergmeyer, editor. Academic Press, New York
    • Fruchart J.C., C. Fievet, and P. Puchois. 1985. Apolipoproteins. In Methods of Enzymatic Analysis. H.U. Bergmeyer, editor. Academic Press, New York. 3:126-138.
    • (1985) Methods of Enzymatic Analysis , vol.3 , pp. 126-138
    • Fruchart, J.C.1    Fievet, C.2    Puchois, P.3
  • 34
    • 0017190667 scopus 로고
    • Enzyme immunoassays in diagnostic medicine. Theory and practice
    • Voller, A., D.E. Bidwell, and A. Bartlett. 1976. Enzyme immunoassays in diagnostic medicine. Theory and practice. Bull. W. H. O. 53:55-65.
    • (1976) Bull. W. H. O. , vol.53 , pp. 55-65
    • Voller, A.1    Bidwell, D.E.2    Bartlett, A.3
  • 35
    • 0023277545 scopus 로고
    • Single step method for RNA isolation by acid guanidinium-thiocyanate-phenol-chloroform extraction
    • Chomczynski, P., and N. Sacchi. 1987. Single step method for RNA isolation by acid guanidinium-thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:156-159.
    • (1987) Anal. Biochem. , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 36
    • 0024354267 scopus 로고
    • Influence of development, oestrogens and food intake on apolipoprotein A-I, A-II and e mRNA in the rat liver and intestine
    • Staels, B., J. Auwerx, L. Chan, A. van Tol, M. Rosseneu, and G. Verhoeven. 1989. Influence of development, oestrogens and food intake on apolipoprotein A-I, A-II and E mRNA in the rat liver and intestine. J. Lipid. Res. 30:1137-1145.
    • (1989) J. Lipid. Res. , vol.30 , pp. 1137-1145
    • Staels, B.1    Auwerx, J.2    Chan, L.3    Van Tol, A.4    Rosseneu, M.5    Verhoeven, G.6
  • 38
    • 0021362861 scopus 로고
    • Molecular cloning of cDNA for rat acyl-CoA oxidase
    • Osumi, T., H. Ozasa, and T. Hashimoto. 1984. Molecular cloning of cDNA for rat acyl-CoA oxidase. J. Biol. Chem. 259:2031-2034.
    • (1984) J. Biol. Chem. , vol.259 , pp. 2031-2034
    • Osumi, T.1    Ozasa, H.2    Hashimoto, T.3
  • 40
    • 0023079956 scopus 로고
    • Isolation and analysis of nuclear RNA
    • Nevins, J.R. 1987. Isolation and analysis of nuclear RNA. Methods Enzymol. 152:234-241.
    • (1987) Methods Enzymol. , vol.152 , pp. 234-241
    • Nevins, J.R.1
  • 41
    • 0023931351 scopus 로고
    • Effects of fenofibrate, gemfibrozil and nicotinic acid on plasma lipoprotein levels in normal and hyperlipidemic mice
    • Olivier, P., M.O. Plancke, D. Marzin, V. Clavey, J. Sauzieres, and J.C. Fruchart. 1988. Effects of fenofibrate, gemfibrozil and nicotinic acid on plasma lipoprotein levels in normal and hyperlipidemic mice. Atherosclerosis. 70:107-114.
    • (1988) Atherosclerosis , vol.70 , pp. 107-114
    • Olivier, P.1    Plancke, M.O.2    Marzin, D.3    Clavey, V.4    Sauzieres, J.5    Fruchart, J.C.6
  • 42
    • 0028997684 scopus 로고
    • Targeted disruption of the α isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators
    • Lee, S.T., T. Pineau, J. Drago, E.J. Lee, J.W. Owens, D.L. Kroetz, P.M. Fernandez-Salguero, H. Westphal, and K.J. Gonzalez. 1995. Targeted disruption of the α isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators. Mol. Cell. Biol. 15:3012-3022.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 3012-3022
    • Lee, S.T.1    Pineau, T.2    Drago, J.3    Lee, E.J.4    Owens, J.W.5    Kroetz, D.L.6    Fernandez-Salguero, P.M.7    Westphal, H.8    Gonzalez, K.J.9
  • 43
    • 0029119082 scopus 로고
    • Fibrates increase human apolipoprotein A-II expression through activation of peroxisome proliferator-activated receptor
    • Vu-Dac, N., K. Schoonjans, V. Kosykh, J. Dallongeville, J.C. Fruchart, B. Staels, and J. Auwerx. 1995. Fibrates increase human apolipoprotein A-II expression through activation of peroxisome proliferator-activated receptor. J. Clin. Invest. 96:741-750.
    • (1995) J. Clin. Invest. , vol.96 , pp. 741-750
    • Vu-Dac, N.1    Schoonjans, K.2    Kosykh, V.3    Dallongeville, J.4    Fruchart, J.C.5    Staels, B.6    Auwerx, J.7
  • 44
    • 0027373567 scopus 로고
    • Protein composition determines the anti-atherogenic properties of HDL in transgenic mice
    • Schultz, J.R., J.G. Verstuyft, E.L. Gong, A.V. Nichols, and E.M. Rubin. 1993. Protein composition determines the anti-atherogenic properties of HDL in transgenic mice. Nature (Lond.). 365:762-764.
    • (1993) Nature (Lond.) , vol.365 , pp. 762-764
    • Schultz, J.R.1    Verstuyft, J.G.2    Gong, E.L.3    Nichols, A.V.4    Rubin, E.M.5
  • 45
    • 0027265618 scopus 로고
    • Atherosclerosis. Insights from the study of transgenic and gene-targeted mice
    • Stoltzfus, L., and E.M. Rubin. 1993. Atherosclerosis. Insights from the study of transgenic and gene-targeted mice. Trends Cardiovasc. Med. 3:130-134.
    • (1993) Trends Cardiovasc. Med. , vol.3 , pp. 130-134
    • Stoltzfus, L.1    Rubin, E.M.2
  • 46
    • 0027183380 scopus 로고
    • Transgenic mouse models of lipoprotein metabolism and atherosclerosis
    • Breslow, J.L. 1993. Transgenic mouse models of lipoprotein metabolism and atherosclerosis. Proc. Natl. Acad. Sci. USA. 90:8314-8318.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 8314-8318
    • Breslow, J.L.1
  • 47
    • 0028290948 scopus 로고
    • Lipoprotein metabolism and atherosclerosis susceptibility in transgenic mice
    • Breslow, J.L. 1994. Lipoprotein metabolism and atherosclerosis susceptibility in transgenic mice. Curr. Opin. Lipidol. 5:175-184.
    • (1994) Curr. Opin. Lipidol. , vol.5 , pp. 175-184
    • Breslow, J.L.1
  • 48
    • 0028596350 scopus 로고
    • Human apolipoprotein A-I prevents atherosclerosis associated with apolipoprotein (a) in transgenic mice
    • Liu, A.C., R.M. Lawn, J.G. Verstuyft, and E.M. Rubin. 1994. Human apolipoprotein A-I prevents atherosclerosis associated with apolipoprotein (a) in transgenic mice. J. Lipid. Res. 35:2263-2267.
    • (1994) J. Lipid. Res. , vol.35 , pp. 2263-2267
    • Liu, A.C.1    Lawn, R.M.2    Verstuyft, J.G.3    Rubin, E.M.4
  • 49
    • 0028167663 scopus 로고
    • Apolipoprotein AI transgene corrects apolipoprotein E deficiency-induced atherosclerosis in mice
    • Paszty, C., N. Maeda, J. Verstuyft, and E.M. Rubin 1994. Apolipoprotein AI transgene corrects apolipoprotein E deficiency-induced atherosclerosis in mice. J. Clin. Invest. 94:899-903.
    • (1994) J. Clin. Invest. , vol.94 , pp. 899-903
    • Paszty, C.1    Maeda, N.2    Verstuyft, J.3    Rubin, E.M.4
  • 50
    • 0028025262 scopus 로고
    • Human apolipoprotein A-I gene expression increase high density lipoprotein and suppresses atherosclerosis in the apolipoprotein E-deficient mouse
    • Plump, A.S., C.J. Scott, and J.L. Breslow. 1994. Human apolipoprotein A-I gene expression increase high density lipoprotein and suppresses atherosclerosis in the apolipoprotein E-deficient mouse. Proc. Natl. Acad. Sci. USA. 91:9607-9611.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 9607-9611
    • Plump, A.S.1    Scott, C.J.2    Breslow, J.L.3
  • 51
    • 0026025868 scopus 로고
    • Synergistic interactions between transcription factors control expression of the apolipoprotein AI gene in liver cells
    • Widom, R.L., J.A.A. Ladias, S. Kouidou, and S.K. Karathanasis. 1991. Synergistic interactions between transcription factors control expression of the apolipoprotein AI gene in liver cells. Mol. Cell. Biol. 11:677-687.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 677-687
    • Widom, R.L.1    Ladias, J.A.A.2    Kouidou, S.3    Karathanasis, S.K.4
  • 52
    • 0028036723 scopus 로고
    • Negative regulation of the human apolipoprotein AI promoter by fibrates can be attenuated by the interaction of the peroxisome-proliferator-activated receptor with its response element
    • Vu-Dac, N., K. Schoonjans, B. Laine, J.C. Fruchart, J. Auwerx, and B. Staels. 1994. Negative regulation of the human apolipoprotein AI promoter by fibrates can be attenuated by the interaction of the peroxisome-proliferator-activated receptor with its response element. J. Biol. Chem. 269:31012-31018.
    • (1994) J. Biol. Chem. , vol.269 , pp. 31012-31018
    • Vu-Dac, N.1    Schoonjans, K.2    Laine, B.3    Fruchart, J.C.4    Auwerx, J.5    Staels, B.6
  • 53
    • 0025992783 scopus 로고
    • Promoter elements and factors involved in hepatic transcription of the human apo A-I gene positive and negative regulators bind to overlapping site
    • Papazafiri, P., K. Ogami, D.P. Ramji, A. Nicosia, P. Monaci, C. Cladaras, and V.I. Zannis. 1991. Promoter elements and factors involved in hepatic transcription of the human apo A-I gene positive and negative regulators bind to overlapping site. J. Biol. Chem. 5790-5797.
    • (1991) J. Biol. Chem. , pp. 5790-5797
    • Papazafiri, P.1    Ogami, K.2    Ramji, D.P.3    Nicosia, A.4    Monaci, P.5    Cladaras, C.6    Zannis, V.I.7
  • 54
    • 0028061943 scopus 로고
    • Activation of apolipoprotein A-I gene transcription by the liver-enriched factor HNF-3
    • Harnish, D., S. Malik, and S.K. Karathanasis. 1994. Activation of apolipoprotein A-I gene transcription by the liver-enriched factor HNF-3. J. Biol. Chem. 269:28220-28226.
    • (1994) J. Biol. Chem. , vol.269 , pp. 28220-28226
    • Harnish, D.1    Malik, S.2    Karathanasis, S.K.3
  • 55
    • 0027229650 scopus 로고
    • HNF-4 increases activity of the rat apo A-I gene
    • Chan, J., H. Nakabayashi, and N.C.W. Wong. 1993. HNF-4 increases activity of the rat apo A-I gene. Nucleic Acids Res. 21:1205-1211.
    • (1993) Nucleic Acids Res. , vol.21 , pp. 1205-1211
    • Chan, J.1    Nakabayashi, H.2    Wong, N.C.W.3
  • 56
    • 0025875141 scopus 로고
    • A retinoic acid-responsive element in the apolipoprotein AI gene distinguishes between two different retinoic acid response pathways
    • Rottman, J.N., R.L. Widom, B. Nadal-Ginard, V. Mahdavi, and S.K. Karathanasis. 1991. A retinoic acid-responsive element in the apolipoprotein AI gene distinguishes between two different retinoic acid response pathways. Mol. Cell. Biol. 11:3814-3820.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 3814-3820
    • Rottman, J.N.1    Widom, R.L.2    Nadal-Ginard, B.3    Mahdavi, V.4    Karathanasis, S.K.5
  • 57
    • 0025804452 scopus 로고
    • Regulation of the apolipoprotein AI gene by ARP-1, a novel member of the steroid receptor superfamily
    • Ladias, J.A.A., and S.K. Karathanasis. 1991. Regulation of the apolipoprotein AI gene by ARP-1, a novel member of the steroid receptor superfamily. Science (Wash. DC). 251:561-565.
    • (1991) Science (Wash. DC) , vol.251 , pp. 561-565
    • Ladias, J.A.A.1    Karathanasis, S.K.2
  • 58
    • 0028238873 scopus 로고
    • Transcriptional repression of apolipoprotein AI gene expression by orphan receptor ARP-1
    • Ge, R., M. Rhee, S. Malik, and S.K. Karathanasis. 1994. Transcriptional repression of apolipoprotein AI gene expression by orphan receptor ARP-1. J. Biol. Chem. 269:13185-13192.
    • (1994) J. Biol. Chem. , vol.269 , pp. 13185-13192
    • Ge, R.1    Rhee, M.2    Malik, S.3    Karathanasis, S.K.4
  • 59
    • 0027255977 scopus 로고
    • Dietary fat increases high density lipoprotein (HDL) levels both by increasing the transport rates and decreasing the fractional catabolic rates of HDL cholesterol ester and apolipoprotein (apo) A-I
    • Hayek, T., Y. Ito, N. Azrolan, R.B. Verdery, K. Aalto-Setälä, A. Walsh, and J.L. Breslow. 1993. Dietary fat increases high density lipoprotein (HDL) levels both by increasing the transport rates and decreasing the fractional catabolic rates of HDL cholesterol ester and apolipoprotein (apo) A-I. J. Clin. Invest. 91:1665-1671.
    • (1993) J. Clin. Invest. , vol.91 , pp. 1665-1671
    • Hayek, T.1    Ito, Y.2    Azrolan, N.3    Verdery, R.B.4    Aalto-Setälä, K.5    Walsh, A.6    Breslow, J.L.7
  • 60
    • 0025740782 scopus 로고
    • Probucol decreases apolipoprotein A-I transport rate and increases high density lipoprotein cholesteryl ester fractional catabolic rate in control and human apolipoprotein A-I transgenic mice
    • Hayek, T., T. Chajek-Shaul, A. Walsh, N. Azrolan, and J.L. Breslow. 1991. Probucol decreases apolipoprotein A-I transport rate and increases high density lipoprotein cholesteryl ester fractional catabolic rate in control and human apolipoprotein A-I transgenic mice. Arterioscler. Thromb. 11:1295-1302.
    • (1991) Arterioscler. Thromb. , vol.11 , pp. 1295-1302
    • Hayek, T.1    Chajek-Shaul, T.2    Walsh, A.3    Azrolan, N.4    Breslow, J.L.5
  • 61
    • 0026501622 scopus 로고
    • Modulation of lipoprotein production in HepG2 cells by fenofibrate and clofibrate
    • Hahn, S.E., and D.M. Goldberg. 1992. Modulation of lipoprotein production in HepG2 cells by fenofibrate and clofibrate. Biochem. Pharmacol. 43: 625-633.
    • (1992) Biochem. Pharmacol. , vol.43 , pp. 625-633
    • Hahn, S.E.1    Goldberg, D.M.2
  • 62
    • 0025726848 scopus 로고
    • Two cis-acting regulatory elements in the peroxisome proliferator-responsive element enhancer region of rat acyl-CoA oxidase gene
    • Osumi, T., J.K. Wen, and T. Hashimoto. 1991. Two cis-acting regulatory elements in the peroxisome proliferator-responsive element enhancer region of rat acyl-CoA oxidase gene. Biochem. Biophys. Res. Commun. 175:866-871.
    • (1991) Biochem. Biophys. Res. Commun. , vol.175 , pp. 866-871
    • Osumi, T.1    Wen, J.K.2    Hashimoto, T.3
  • 63
    • 8944255721 scopus 로고
    • The human apolipoprotein A1 promoter contains a novel PPRE
    • Abstr.
    • Klausing, K., R. Straney, and M. Briggs. 1995. The human apolipoprotein A1 promoter contains a novel PPRE. Circulation. 92:I-291. (Abstr.)
    • (1995) Circulation , vol.92
    • Klausing, K.1    Straney, R.2    Briggs, M.3
  • 64
    • 0028998129 scopus 로고
    • Mode of action of peroxisome proliferators as hypolipidemic drugs. Suppression of apolipoprotein C-III
    • Hertz, R., J. Bishara-Shieban, and J. Bar-Tana. 1995. Mode of action of peroxisome proliferators as hypolipidemic drugs. Suppression of apolipoprotein C-III. J. Biol. Chem. 270:13470-13475.
    • (1995) J. Biol. Chem. , vol.270 , pp. 13470-13475
    • Hertz, R.1    Bishara-Shieban, J.2    Bar-Tana, J.3
  • 65
    • 0022362750 scopus 로고
    • Apolipoprotein changes associated with the plasma lipid-regulating activity of gemfibrozil in cholesterol-fed rats
    • Krause, B.R., and R.S Newton. 1985. Apolipoprotein changes associated with the plasma lipid-regulating activity of gemfibrozil in cholesterol-fed rats. J. Lipid. Res. 26:940-949.
    • (1985) J. Lipid. Res. , vol.26 , pp. 940-949
    • Krause, B.R.1    Newton, R.S.2
  • 66
    • 0022619159 scopus 로고
    • Gemfibrozil increases both apo A-I and apo e concentrations. Comparison to other lipids regulators in cholesterol-fed rats
    • Krause, B.R., and R.S Newton. 1986 Gemfibrozil increases both apo A-I and apo E concentrations. Comparison to other lipids regulators in cholesterol-fed rats. Atherosclerosis. 59:95-98.
    • (1986) Atherosclerosis , vol.59 , pp. 95-98
    • Krause, B.R.1    Newton, R.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.