PPAR-α and PPAR-γ activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway

Nature Medicine

Volumn 7, Issue 1, 2001, Pages 53-58

  Chinetti, Giulia ^a   Lestavel, Sophie ^a   Bocher, Virginie ^a   Remaley, Alan T ^b   Neve, Bernadette ^a   Torra, Inés Pineda ^a   Teissier, Elisabeth ^a   Minnich, Anne ^c   Jaye, Michael ^c   Duverger, Nicolas ^d   Brewer, H Bryan ^b   Fruchart, Jean Charles ^a   Clavey, Véronique ^a   Staels, Bart ^a  

^a UNIV LILLE   (France)

^b NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^c Aventis Pharmaceuticals   (United States)

^d SANOFI   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; ACETYL LOW DENSITY LIPOPROTEIN; APOLIPOPROTEIN A1; CELL NUCLEUS RECEPTOR; LIVER X RECEPTOR ALPHA; OXYSTEROL; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PIRINIXIC ACID; PROTEIN ABC 1; ROSIGLITAZONE; UNCLASSIFIED DRUG;

ARTICLE; CHOLESTEROL METABOLISM; CHOLESTEROL TRANSPORT; DRUG ACTIVITY; DRUG EFFECT; FOAM CELL; GENE EXPRESSION; HUMAN; HUMAN CELL; MACROPHAGE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR INTRINSIC ACTIVITY; TANGIER DISEASE; TRANSCRIPTION REGULATION;

EID: 0035138625     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/83348     Document Type: Article

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