Delivery of Chlamydia pneumoniae to the vessel wall aggravates atherosclerosis in LDLr-/- mice

Cardiovascular Research

Volumn 69, Issue 1, 2006, Pages 280-288

  Hauer, A D ^a,d,e   De Vos, P ^a   Peterse, N ^a   Ten Cate, H ^b   Van Berkel, Th J C ^a   Stassen, F R M ^c   Kuiper, J ^a  

^a LEIDEN UNIVERSITY   (Netherlands)

^b MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^c MAASTRICHT UNIVERSITY   (Netherlands)

^d LEIDEN UNIVERSITY   (Netherlands)

^e NONE   (Netherlands)

Author keywords

Atherosclerosis; Chlamydia pneumoniae; Inflammation; Mouse model

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY WALL; ARTICLE; ATHEROSCLEROSIS; BLOOD VESSEL WALL; CAROTID ARTERY; CHLAMYDOPHILA PNEUMONIAE; CONTROLLED STUDY; MACROPHAGE; MALE; MOUSE; MYCOPLASMA PNEUMONIAE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SMOOTH MUSCLE FIBER; UPREGULATION;

ANIMALS; ATHEROSCLEROSIS; CAROTID ARTERIES; CAROTID ARTERY DISEASES; CAROTID ARTERY INJURIES; CHEMOKINE CCL2; CHLAMYDOPHILA INFECTIONS; CHLAMYDOPHILA PNEUMONIAE; COLLAGEN; ENDOTHELIAL CELLS; IMMUNOHISTOCHEMISTRY; INTERCELLULAR ADHESION MOLECULE-1; MACROPHAGES; MICE; MICE, KNOCKOUT; MODELS, ANIMAL; MUSCLE, SMOOTH, VASCULAR; MYCOPLASMA PNEUMONIAE; RECEPTORS, LDL; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 29144521809     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cardiores.2005.07.011     Document Type: Article

References (45)

1. R. Ross Atherosclerosis-an inflammatory disease N Engl J Med 340 1999 115 126
2. J.T. Grayston Infections caused by Chlamydia pneumoniae strain TWAR Clin Infect Dis 15 1992 757 761
3. P. Saikku, M. Leinonen, K. Mattila, M.R. Ekman, M.S. Nieminen, and P.H. Makela Serological evidence of an association of a novel Chlamydia, TWAR, with chronic coronary heart disease and acute myocardial infarction Lancet 2 1988 983 986
4. T.C. Moazed, C.C. Kuo, J.T. Grayston, and L.A. Campbell Evidence of systemic dissemination of Chlamydia pneumoniae via macrophages in the mouse J Infect Dis 177 1998 1322 1325
5. C.C. Kuo, A. Shor, L.A. Campbell, H. Fukushi, D.L. Patton, and J.T. Grayston Demonstration of Chlamydia pneumoniae in atherosclerotic lesions of coronary arteries J Infect Dis 167 1993 841 849
6. J.B. Muhlestein Antibiotic treatment of atherosclerosis Curr Opin Lipidol 14 2003 605 614
7. S.S. Kaukoranta-Tolvanen, T. Ronni, M. Leinonen, P. Saikku, and K. Laitinen Expression of adhesion molecules on endothelial cells stimulated by Chlamydia pneumoniae Microb Pathog 21 1996 407 411
8. R.E. Molestina, R.D. Miller, J.A. Ramirez, and J.T. Summersgill Infection of human endothelial cells with Chlamydia pneumoniae stimulates transendothelial migration of neutrophils and monocytes Infect Immun 67 1999 1323 1330
9. B.K. Coombes, and J.B. Mahony cDNA array analysis of altered gene expression in human endothelial cells in response to Chlamydia pneumoniae infection Infect Immun 69 2001 1420 1427
10. M.V. Kalayoglu, B.N. Perkins, and G.I. Byrne Chlamydia pneumoniae-infected monocytes exhibit increased adherence to human aortic endothelial cells Microbes Infect 3 2001 963 969
11. A.E. May, V. Redecke, S. Gruner, R. Schmidt, S. Massberg, and T. Miethke Recruitment of Chlamydia pneumoniae-infected macrophages to the carotid artery wall in noninfected, nonatherosclerotic mice Arterioscler Thromb Vasc Biol 23 2003 789 794
12. M.V. Kalayoglu, B. Hoerneman, D. LaVerda, S.G. Morrison, R.P. Morrison, and G.I. Byrne Cellular oxidation of low-density lipoprotein by Chlamydia pneumoniae J Infect Dis 180 1999 780 790
13. R. Dittrich, C. Dragonas, A. Mueller, T. Maltaris, J. Rupp, and M.W. Beckmann Endothelial Chlamydia pneumoniae infection promotes oxidation of LDL Biochem Biophys Res Commun 319 2004 501 505
14. J. Rodel, D. Prochnau, K. Prager, E. Pentcheva, M. Hartmann, and E. Straube Increased production of matrix metalloproteinases 1 and 3 by smooth muscle cells upon infection with Chlamydia pneumoniae FEMS Immunol Med Microbiol 38 2003 159 164
15. L.A. Campbell, M. Rosenfeld, and C.C. Kuo The role of Chlamydia pneumoniae in atherosclerosis-recent evidence from animal models Trends Microbiol 8 2000 255 257
16. G. Caligiuri, M. Rottenberg, A. Nicoletti, H. Wigzell, and G.K. Hansson Chlamydia pneumoniae infection does not induce or modify atherosclerosis in mice Circulation 103 2001 2834 2838
17. M.L. Higuchi, N. Sambiase, S. Palomino, P. Gutierrez, L.M. Demarchi, and V.D. Aiello Detection of Mycoplasma pneumoniae and Chlamydia pneumoniae in ruptured atherosclerotic plaques Braz J Med Biol Res 33 2000 1023 1026
18. D. Taylor-Robinson Chlamydia pneumoniae infection and coronary heart disease. Trials should assess whether antibiotics eliminate organism from atherosclerotic lesions BMJ 315 1997 1538
19. R.P. Verkooyen, S. Harreveld, S. Ahmad Mousavi Joulandan, R.J. Diepersloot, and H.A. Verbrugh Survival of Chlamydia pneumoniae following contact with various surfaces Clin Microbiol Infect 1 1995 114 118
20. J.H. von der Thusen, T.J. van Berkel, and E.A. Biessen Induction of rapid atherogenesis by perivascular carotid collar placement in apolipoprotein E-deficient and low-density lipoprotein receptor-deficient mice Circulation 103 2001 1164 1170
21. -/- mice after adenovirus-mediated transfer of p53 Circulation 105 2002 2064 2070
22. H. Weiler, V. Lindner, B. Kerlin, B.H. Isermann, S.B. Hendrickson, and B.C. Cooley Characterization of a mouse model for thrombomodulin deficiency Arterioscler Thromb Vasc Biol 21 2001 1531 1537
23. C.A. Jantos, S. Heck, R. Roggendorf, M. Sen-Gupta, and J.H. Hegemann Antigenic and molecular analyses of different Chlamydia pneumoniae strains J Clin Microbiol 35 1997 620 623
24. M. Hoekstra, J.K. Kruijt, M. Van Eck, and T.J. Van Berkel Specific gene expression of ATP-binding cassette transporters and nuclear hormone receptors in rat liver parenchymal, endothelial, and Kupffer cells J Biol Chem 278 2003 25448 25453
25. S.V. Pislaru, M. Van Ranst, C. Pislaru, Z. Szelid, G. Theilmeier, and J.M. Ossewaarde Chlamydia pneumoniae induces neointima formation in coronary arteries of normal pigs Cardiovasc Res 57 2003 834 842
26. J.B. Muhlestein Chlamydia pneumoniae-induced atherosclerosis in a rabbit model J Infect Dis 181 Suppl 3 2000 S505 S507
27. V.Y. Hoymans, J.M. Bosmans, D. Ursi, W. Martinet, F.L. Wuyts, and E. Van Marck Immunohistostaining assays for detection of Chlamydia pneumoniae in atherosclerotic arteries indicate cross-reactions with nonchlamydial plaque constituents J Clin Microbiol 42 2004 3219 3224
28. K. Laitinen, A. Laurila, L. Pyhala, M. Leinonen, and P. Saikku Chlamydia pneumoniae infection induces inflammatory changes in the aortas of rabbits Infect Immun 65 1997 4832 4835
29. C.A. Gaydos, J.T. Summersgill, N.N. Sahney, J.A. Ramirez, and T.C. Quinn Replication of Chlamydia pneumoniae in vitro in human macrophages, endothelial cells, and aortic artery smooth muscle cells Infect Immun 64 1996 1614 1620
30. D. Neureiter, P. Heuschmann, S. Stintzing, P. Kolominsky-Rabas, L. Barbera, and A. Jung Detection of Chlamydia pneumoniae but not of Helicobacter pylori in symptomatic atherosclerotic carotids associated with enhanced serum antibodies, inflammation and apoptosis rate Atherosclerosis 168 2003 153 162
31. K. Aalto-Setala, K. Laitinen, L. Erkkila, M. Leinonen, M. Jauhiainen, and C. Ehnholm Chlamydia pneumoniae does not increase atherosclerosis in the aortic root of apolipoprotein E-deficient mice Arterioscler Thromb Vasc Biol 21 2001 578 584
32. L.A. Campbell, E. Blessing, M. Rosenfeld, T. Lin, and C. Kuo Mouse models of C. pneumoniae infection and atherosclerosis J Infect Dis 181 Suppl 3 2000 S508 S513
33. M. Davidson, C.C. Kuo, J.P. Middaugh, L.A. Campbell, S.P. Wang, and W.P. Newman III Confirmed previous infection with Chlamydia pneumoniae (TWAR) and its presence in early coronary atherosclerosis Circulation 98 1998 628 633
34. Y. Geng, R.B. Shane, K. Berencsi, E. Gonczol, M.H. Zaki, and D.J. Margolis Chlamydia pneumoniae inhibits apoptosis in human peripheral blood mononuclear cells through induction of IL-10 J Immunol 164 2000 5522 5529
35. B.K. Coombes, and J.B. Mahony Chlamydia pneumoniae infection of human endothelial cells induces proliferation of smooth muscle cells via an endothelial cell-derived soluble factor(s) Infect Immun 67 1999 2909 2915
36. S. Sasu, D. LaVerda, N. Qureshi, D.T. Golenbock, and D. Beasley Chlamydia pneumoniae and chlamydial heat shock protein 60 stimulate proliferation of human vascular smooth muscle cells via toll-like receptor 4 and p44/p42 mitogen-activated protein kinase activation Circ Res 89 2001 244 250
37. J. Rodel, D. Prochnau, K. Prager, J. Baumert, K.H. Schmidt, and E. Straube Chlamydia pneumoniae decreases smooth muscle cell proliferation through induction of prostaglandin E2 synthesis Infect Immun 72 2004 4900 4904
38. B.K. Coombes, B. Chiu, I.W. Fong, and J.B. Mahony Chlamydia pneumoniae infection of endothelial cells induces transcriptional activation of platelet-derived growth factor-B: a potential link to intimal thickening in a rabbit model of atherosclerosis J Infect Dis 185 2002 1621 1630
39. R. Ezzahiri, F.R. Stassen, H.A. Kurvers, M.M. van Pul, P.J. Kitslaar, and C.A. Bruggeman Chlamydia pneumoniae infection induces an unstable atherosclerotic plaque phenotype in LDL-receptor, ApoE double knockout mice Eur J Vasc Endovasc Surg 26 2003 88 95
40. A. Kol, G.K. Sukhova, A.H. Lichtman, and P. Libby Chlamydial heat shock protein 60 localizes in human atheroma and regulates macrophage tumor necrosis factor-alpha and matrix metalloproteinase expression Circulation 98 1998 300 307
41. R. Dechend, J. Gieffers, R. Dietz, A. Joerres, J. Rupp, and F.C. Luft Hydroxymethylglutaryl coenzyme A reductase inhibition reduces Chlamydia pneumoniae-induced cell interaction and activation Circulation 108 2003 261 265
42. R. Dechend, M. Maass, J. Gieffers, R. Dietz, C. Scheidereit, and A. Leutz Chlamydia pneumoniae infection of vascular smooth muscle and endothelial cells activates NF-kappaB and induces tissue factor and PAI-1 expression: a potential link to accelerated arteriosclerosis Circulation 100 1999 1369 1373
43. F. Bea, M.H. Puolakkainen, T. McMillen, F.N. Hudson, N. Mackman, and C.C. Kuo Chlamydia pneumoniae induces tissue factor expression in mouse macrophages via activation of Egr-1 and the MEK-ERK1/2 pathway Circ Res 92 2003 394 401
44. S.R. Goth, and R.S. Stephens Rapid, transient phosphatidylserine externalization induced in host cells by infection with Chlamydia spp Infect Immun 69 2001 1109 1119
45. G. Caligiuri, M. Rudling, V. Ollivier, M.P. Jacob, J.B. Michel, and G.K. Hansson Interleukin-10 deficiency increases atherosclerosis, thrombosis, and low-density lipoproteins in apolipoprotein E knockout mice Mol Med 9 2003 10 17