Overexpression of human 15(S)-lipoxygenase-1 in RAW macrophages leads to increased cholesterol mobilization and reverse cholesterol transport

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 29, Issue 6, 2009, Pages 837-842

  Weibel, Ginny L ^a   Joshi, Michelle R ^a   Alexander, Eric T ^a   Zhu, Peijuan ^b   Blair, Ian A ^b   Rothblat, George H ^a  

^a CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

ABCA 1; Lipoxygenase; Macrophage; Reverse cholesterol transport

Indexed keywords

15 HYDROXYICOSATETRAENOIC ACID; 15 LIPOXYGENASE 1; ABC TRANSPORTER A1; ABC TRANSPORTER G1; ACETYL LOW DENSITY LIPOPROTEIN; APOLIPOPROTEIN A1; ARACHIDONATE 15 LIPOXYGENASE; ARACHIDONIC ACID; CHOLESTEROL; CHOLESTEROL ESTER; ICOSANOID; MESSENGER RNA; TRITIUM; UNCLASSIFIED DRUG; 15 HYDROXY 5,8,11,13 ICOSATETRAENOIC ACID; 15-HYDROXY-5,8,11,13-EICOSATETRAENOIC ACID; ABC TRANSPORTER; ABCG1 PROTEIN, MOUSE; ACETYL-LDL; ALOX15 PROTEIN, HUMAN; CHOLESTEROL ESTER TRANSFER PROTEIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HYDROXYICOSATETRAENOIC ACID; LIPOPROTEIN; LOW DENSITY LIPOPROTEIN;

ANIMAL CELL; ARACHIDONIC ACID METABOLISM; ARTICLE; CELL LINE; CELL MOTILITY; CHOLESTEROL METABOLISM; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; ENZYME SYNTHESIS; FECES; GENE OVEREXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HYDROLYSIS; ICOSANOID METABOLISM; IMMUNOBLOTTING; INJECTION; MACROPHAGE; NONHUMAN; OXYGENATION; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; REVERSE CHOLESTEROL TRANSPORT; ANIMAL; CHEMISTRY; ENZYMOLOGY; GENETICS; METABOLISM; MOUSE; TIME; TRANSPLANTATION; TRANSPORT AT THE CELLULAR LEVEL; UPREGULATION;

ANIMALS; APOLIPOPROTEIN A-I; ARACHIDONATE 15-LIPOXYGENASE; ATP-BINDING CASSETTE TRANSPORTERS; BIOLOGICAL TRANSPORT; CELL LINE; CHOLESTEROL; CHOLESTEROL ESTER TRANSFER PROTEINS; CHOLESTEROL ESTERS; CHOLESTEROL, HDL; FECES; HUMANS; HYDROLYSIS; HYDROXYEICOSATETRAENOIC ACIDS; LIPOPROTEINS; LIPOPROTEINS, LDL; MACROPHAGES; MICE; RNA, MESSENGER; TIME FACTORS; TRANSFECTION; TRITIUM; UP-REGULATION;

EID: 66349110576     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/ATVBAHA.109.186163     Document Type: Article

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