The target of ezetimibe is Niemann-Pick C1-Like 1 (NPC1L1)

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 23, 2005, Pages 8132-8137

  Garcia Calvo, Margarita ^a   Lisnock, JeanMarie ^a   Bull, Herbert G ^a   Hawes, Brian E ^a   Burnett, Duane A ^a   Braun, Matthew P ^a   Crona, James H ^a   Davis Jr , Harry R ^a   Dean, Dennis C ^a   Detmers, Patricia A ^a   Graziano, Michael P ^a   Hughes, Meredith ^a   MacIntyre, D Euan ^a   Ogawa, Anthony ^a   O'Neil, Kim A ^a   Iyer, Sai Prasad N ^a   Shevell, Diane E ^a   Smith, Marsha M ^a   Tang, Yui S ^a   Makarewicz, Amanda M ^a   Ujjainwalla, Feroze ^a   Altmann, Scott W ^a   Chapman, Kevin T ^a   Thornberry, Nancy A ^a   more..

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Cholesterol; Intestinal brush border membranes

Indexed keywords

CHOLESTEROL; EZETIMIBE;

ARTICLE; BINDING AFFINITY; BINDING SITE; BRUSH BORDER; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; DRUG GLUCURONIDATION; DRUG TARGETING; GENE; GENE EXPRESSION; HUMAN; HUMAN CELL; HYPERCHOLESTEROLEMIA; INTESTINE CELL; KNOCKOUT MOUSE; MEMBRANE BINDING; MOLECULAR MECHANICS; MOLECULAR TARGET; NPC1L1 GENE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL;

ANIMALS; AZETIDINES; BINDING SITES; CELL LINE; CELL MEMBRANE; ENTEROCYTES; HUMANS; INTESTINES; MACACA MULATTA; MEMBRANE PROTEINS; MEMBRANE TRANSPORT PROTEINS; MICE; MICE, INBRED C57BL; MICROVILLI; NIEMANN-PICK DISEASES; PROTEIN BINDING; PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; SPECIES SPECIFICITY;

MACACA MULATTA;

EID: 20444371945     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0500269102     Document Type: Article

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