메뉴 건너뛰기




Volumn 98, Issue C, 2011, Pages 293-347

Molecular targets of alcohol action: Translational research for pharmacotherapy development and screening

Author keywords

Alcohol; Animal models; Behavior; Biomarkers; Complex trait disorders; Dependence; Drug development; Gene expression; Phenotype; Proteomics

Indexed keywords


EID: 78650897821     PISSN: 18771173     EISSN: None     Source Type: Book Series    
DOI: 10.1016/B978-0-12-385506-0.00007-7     Document Type: Chapter
Times cited : (14)

References (310)
  • 3
    • 0031734499 scopus 로고    scopus 로고
    • General and specific inheritance of substance abuse and alcoholism
    • D. Goldman, and A. Bergen General and specific inheritance of substance abuse and alcoholism Arch Gen Psychiatry 55 1998 964 965
    • (1998) Arch Gen Psychiatry , vol.55 , pp. 964-965
    • Goldman, D.1    Bergen, A.2
  • 4
    • 0031666579 scopus 로고    scopus 로고
    • Comorbidity of substance use disorders with mood and anxiety disorders: Results of the International Consortium in Psychiatric Epidemiology
    • K.R. Merikangas, R.L. Mehta, B.E. Molnar, E.E. Walters, J.D. Swendsen, and S. Aguilar-Gaziola Comorbidity of substance use disorders with mood and anxiety disorders: results of the International Consortium in Psychiatric Epidemiology Addict Behav 23 1998 893 907
    • (1998) Addict Behav , vol.23 , pp. 893-907
    • Merikangas, K.R.1    Mehta, R.L.2    Molnar, B.E.3    Walters, E.E.4    Swendsen, J.D.5    Aguilar-Gaziola, S.6
  • 5
    • 0038811920 scopus 로고    scopus 로고
    • Specificity of genetic and environmental risk factors for use and abuse/dependence of cannabis, cocaine, hallucinogens, sedatives, stimulants, and opiates in male twins
    • K.S. Kendler, K.C. Jacobson, C.A. Prescott, and M.C. Neale Specificity of genetic and environmental risk factors for use and abuse/dependence of cannabis, cocaine, hallucinogens, sedatives, stimulants, and opiates in male twins Am J Psychiatry 160 2003 687 695
    • (2003) Am J Psychiatry , vol.160 , pp. 687-695
    • Kendler, K.S.1    Jacobson, K.C.2    Prescott, C.A.3    Neale, M.C.4
  • 6
  • 7
    • 12144288685 scopus 로고    scopus 로고
    • Variations in GABRA2, encoding the alpha 2 subunit of the GABA(A) receptor, are associated with alcohol dependence and with brain oscillations
    • H.J. Edenberg, D.M. Dick, X. Xuei, H. Tian, L. Almasy, and L.O. Bauer Variations in GABRA2, encoding the alpha 2 subunit of the GABA(A) receptor, are associated with alcohol dependence and with brain oscillations Am J Hum Genet 74 2004 705 714
    • (2004) Am J Hum Genet , vol.74 , pp. 705-714
    • Edenberg, H.J.1    Dick, D.M.2    Xuei, X.3    Tian, H.4    Almasy, L.5    Bauer, L.O.6
  • 8
    • 20244368365 scopus 로고    scopus 로고
    • Association between alcoholism and gamma-amino butyric acid alpha2 receptor subtype in a Russian population
    • J. Lappalainen, E. Krupitsky, M. Remizov, S. Pchelina, A. Taraskina, and E. Zvartau Association between alcoholism and gamma-amino butyric acid alpha2 receptor subtype in a Russian population Alcohol Clin Exp Res 29 2005 493 498
    • (2005) Alcohol Clin Exp Res , vol.29 , pp. 493-498
    • Lappalainen, J.1    Krupitsky, E.2    Remizov, M.3    Pchelina, S.4    Taraskina, A.5    Zvartau, E.6
  • 9
    • 33745659406 scopus 로고    scopus 로고
    • The role of GABRA2 in risk for conduct disorder and alcohol and drug dependence across developmental stages
    • D.M. Dick, L. Bierut, A. Hinrichs, L. Fox, K.K. Bucholz, and J. Kramer The role of GABRA2 in risk for conduct disorder and alcohol and drug dependence across developmental stages Behav Genet 36 2006 577 590
    • (2006) Behav Genet , vol.36 , pp. 577-590
    • Dick, D.M.1    Bierut, L.2    Hinrichs, A.3    Fox, L.4    Bucholz, K.K.5    Kramer, J.6
  • 10
    • 0033137333 scopus 로고    scopus 로고
    • D2 dopamine receptor gene (DRD2) allele and haplotype frequencies in alcohol dependent and control subjects: No association with phenotype or severity of phenotype
    • J. Gelernter, and H. Kranzler D2 dopamine receptor gene (DRD2) allele and haplotype frequencies in alcohol dependent and control subjects: no association with phenotype or severity of phenotype Neuropsychopharmacology 20 1999 640 649
    • (1999) Neuropsychopharmacology , vol.20 , pp. 640-649
    • Gelernter, J.1    Kranzler, H.2
  • 11
    • 2942746257 scopus 로고    scopus 로고
    • Linkage and linkage disequilibrium of evoked EEG oscillations with CHRM2 receptor gene polymorphisms: Implications for human brain dynamics and cognition
    • K.A. Jones, B. Porjesz, L. Almasy, L. Bierut, A. Goate, and J.C. Wang Linkage and linkage disequilibrium of evoked EEG oscillations with CHRM2 receptor gene polymorphisms: implications for human brain dynamics and cognition Int J Psychophysiol 53 2004 75 90
    • (2004) Int J Psychophysiol , vol.53 , pp. 75-90
    • Jones, K.A.1    Porjesz, B.2    Almasy, L.3    Bierut, L.4    Goate, A.5    Wang, J.C.6
  • 12
    • 33646127794 scopus 로고    scopus 로고
    • Association of alcohol dehydrogenase genes with alcohol dependence: A comprehensive analysis
    • H.J. Edenberg, X. Xuei, H.J. Chen, H. Tian, L.F. Wetherill, and D.M. Dick Association of alcohol dehydrogenase genes with alcohol dependence: a comprehensive analysis Hum Mol Genet 15 2006 1539 1549
    • (2006) Hum Mol Genet , vol.15 , pp. 1539-1549
    • Edenberg, H.J.1    Xuei, X.2    Chen, H.J.3    Tian, H.4    Wetherill, L.F.5    Dick, D.M.6
  • 13
    • 34548590486 scopus 로고    scopus 로고
    • Family-based association analyses of alcohol dependence phenotypes across DRD2 and neighboring gene ANKK1
    • D.M. Dick, J.C. Wang, J. Plunkett, F. Aliev, A. Hinrichs, and S. Bertelsen Family-based association analyses of alcohol dependence phenotypes across DRD2 and neighboring gene ANKK1 Alcohol Clin Exp Res 31 2007 1645 1653
    • (2007) Alcohol Clin Exp Res , vol.31 , pp. 1645-1653
    • Dick, D.M.1    Wang, J.C.2    Plunkett, J.3    Aliev, F.4    Hinrichs, A.5    Bertelsen, S.6
  • 14
    • 0033973444 scopus 로고    scopus 로고
    • DRD4 exon III VNTR polymorphism - Susceptibility factor for heroin dependence? Results of a case-control and a family-based association approach
    • P. Franke, M.M. Nothen, T. Wang, M. Knapp, D. Lichtermann, and H. Neidt DRD4 exon III VNTR polymorphism-susceptibility factor for heroin dependence? Results of a case-control and a family-based association approach Mol Psychiatry 5 2000 101 104 (Pubitemid 30088460)
    • (2000) Molecular Psychiatry , vol.5 , Issue.1 , pp. 101-104
    • Franke, P.1    Nothen, M.M.2    Wang, T.3    Knapp, M.4    Lichtermann, D.5    Neidt, H.6    Sander, T.7    Propping, P.8    Maier, W.9
  • 15
    • 0033989459 scopus 로고    scopus 로고
    • Pharmacogenetics of responses to alcohol and genes that influence alcohol drinking
    • T.K. Li Pharmacogenetics of responses to alcohol and genes that influence alcohol drinking J Stud Alcohol 61 2000 5 12
    • (2000) J Stud Alcohol , vol.61 , pp. 5-12
    • Li, T.K.1
  • 16
    • 43049171797 scopus 로고    scopus 로고
    • A systematic single nucleotide polymorphism screen to fine-map alcohol dependence genes on chromosome 7 identifies association with a novel susceptibility gene ACN9
    • D.M. Dick, F. Aliev, J.C. Wang, S. Saccone, A. Hinrichs, and S. Bertelsen A systematic single nucleotide polymorphism screen to fine-map alcohol dependence genes on chromosome 7 identifies association with a novel susceptibility gene ACN9 Biol Psychiatry 63 2008 1047 1053
    • (2008) Biol Psychiatry , vol.63 , pp. 1047-1053
    • Dick, D.M.1    Aliev, F.2    Wang, J.C.3    Saccone, S.4    Hinrichs, A.5    Bertelsen, S.6
  • 19
    • 0035199891 scopus 로고    scopus 로고
    • Drug addiction, dysregulation of reward, and allostasis
    • G.F. Koob, and M. Le Moal Drug addiction, dysregulation of reward, and allostasis Neuropsychopharmacology 24 2001 97 129
    • (2001) Neuropsychopharmacology , vol.24 , pp. 97-129
    • Koob, G.F.1    Le Moal, M.2
  • 20
    • 33749478205 scopus 로고    scopus 로고
    • Genetics and the future of clinical psychiatry
    • A.R. Hariri, and D.A. Lewis Genetics and the future of clinical psychiatry Am J Psychiatry 163 2006 1676 1678
    • (2006) Am J Psychiatry , vol.163 , pp. 1676-1678
    • Hariri, A.R.1    Lewis, D.A.2
  • 22
    • 0037624040 scopus 로고    scopus 로고
    • Influence of life stress on depression: Moderation by a polymorphism in the 5-HTT gene
    • A. Caspi, K. Sugden, T.E. Moffitt, A. Taylor, I.W. Craig, and H. Harrington Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene Science 301 2003 386 389
    • (2003) Science , vol.301 , pp. 386-389
    • Caspi, A.1    Sugden, K.2    Moffitt, T.E.3    Taylor, A.4    Craig, I.W.5    Harrington, H.6
  • 24
    • 0026653230 scopus 로고
    • Vulnerability to drug abuse among opioid addicts' siblings: Individual, familial, and peer influences
    • S.S. Luthar, S.F. Anton, K.R. Merikangas, and B.J. Rounsaville Vulnerability to drug abuse among opioid addicts' siblings: individual, familial, and peer influences Compr Psychiatry 33 1992 190 196
    • (1992) Compr Psychiatry , vol.33 , pp. 190-196
    • Luthar, S.S.1    Anton, S.F.2    Merikangas, K.R.3    Rounsaville, B.J.4
  • 25
    • 0031791365 scopus 로고    scopus 로고
    • Familial transmission of substance dependence: Alcohol, marijuana, cocaine, and habitual smoking: A report from the Collaborative Study on the Genetics of Alcoholism
    • L.J. Bierut, S.H. Dinwiddie, H. Begleiter, R.R. Crowe, V. Hesselbrock, and J.I. Nurnberger Jr. Familial transmission of substance dependence: alcohol, marijuana, cocaine, and habitual smoking: a report from the Collaborative Study on the Genetics of Alcoholism Arch Gen Psychiatry 55 1998 982 988
    • (1998) Arch Gen Psychiatry , vol.55 , pp. 982-988
    • Bierut, L.J.1    Dinwiddie, S.H.2    Begleiter, H.3    Crowe, R.R.4    Hesselbrock, V.5    Nurnberger Jr., J.I.6
  • 27
    • 0032941383 scopus 로고    scopus 로고
    • Children of alcoholics exhibit attenuated cognitive impairment during an ethanol challenge
    • J. Erblich, and M. Earleywine Children of alcoholics exhibit attenuated cognitive impairment during an ethanol challenge Alcohol Clin Exp Res 23 1999 476 482
    • (1999) Alcohol Clin Exp Res , vol.23 , pp. 476-482
    • Erblich, J.1    Earleywine, M.2
  • 28
    • 0029983168 scopus 로고    scopus 로고
    • The electroencephalogram after alcohol administration in high-risk men and the development of alcohol use disorders 10 years later
    • J. Volavka, P. Czobor, D.W. Goodwin, W.F. Gabrielli Jr., E.C. Penick, and S.A. Mednick The electroencephalogram after alcohol administration in high-risk men and the development of alcohol use disorders 10 years later Arch Gen Psychiatry 53 1996 258 263
    • (1996) Arch Gen Psychiatry , vol.53 , pp. 258-263
    • Volavka, J.1    Czobor, P.2    Goodwin, D.W.3    Gabrielli Jr., W.F.4    Penick, E.C.5    Mednick, S.A.6
  • 29
    • 0033638443 scopus 로고    scopus 로고
    • The relationships of a family history of alcohol dependence, a low level of response to alcohol and six domains of life functioning to the development of alcohol use disorders
    • M.A. Schuckit, and T.L. Smith The relationships of a family history of alcohol dependence, a low level of response to alcohol and six domains of life functioning to the development of alcohol use disorders J Stud Alcohol 61 2000 827 835
    • (2000) J Stud Alcohol , vol.61 , pp. 827-835
    • Schuckit, M.A.1    Smith, T.L.2
  • 30
    • 6344228776 scopus 로고    scopus 로고
    • The search for genes contributing to the low level of response to alcohol: Patterns of findings across studies
    • M.A. Schuckit, T.L. Smith, and J. Kalmijn The search for genes contributing to the low level of response to alcohol: patterns of findings across studies Alcohol Clin Exp Res 28 2004 1449 1458
    • (2004) Alcohol Clin Exp Res , vol.28 , pp. 1449-1458
    • Schuckit, M.A.1    Smith, T.L.2    Kalmijn, J.3
  • 31
    • 0025896673 scopus 로고
    • Platelet serotonin uptake in men with family histories of alcoholism
    • J.L. Rausch, M.G. Monteiro, and M.A. Schuckit Platelet serotonin uptake in men with family histories of alcoholism Neuropsychopharmacology 4 1991 83 86
    • (1991) Neuropsychopharmacology , vol.4 , pp. 83-86
    • Rausch, J.L.1    Monteiro, M.G.2    Schuckit, M.A.3
  • 32
    • 0038662872 scopus 로고    scopus 로고
    • Serotonin transporter gene variation is associated with alcohol sensitivity in rhesus macaques exposed to early-life stress
    • C.S. Barr, T.K. Newman, M.L. Becker, M. Champoux, K.P. Lesch, and S.J. Suomi Serotonin transporter gene variation is associated with alcohol sensitivity in rhesus macaques exposed to early-life stress Alcohol Clin Exp Res 27 2003 812 817
    • (2003) Alcohol Clin Exp Res , vol.27 , pp. 812-817
    • Barr, C.S.1    Newman, T.K.2    Becker, M.L.3    Champoux, M.4    Lesch, K.P.5    Suomi, S.J.6
  • 33
    • 12344328265 scopus 로고    scopus 로고
    • An expanded evaluation of the relationship of four alleles to the level of response to alcohol and the alcoholism risk
    • X. Hu, G. Oroszi, J. Chun, T.L. Smith, D. Goldman, and M.A. Schuckit An expanded evaluation of the relationship of four alleles to the level of response to alcohol and the alcoholism risk Alcohol Clin Exp Res 29 2005 8 16
    • (2005) Alcohol Clin Exp Res , vol.29 , pp. 8-16
    • Hu, X.1    Oroszi, G.2    Chun, J.3    Smith, T.L.4    Goldman, D.5    Schuckit, M.A.6
  • 34
    • 33746257088 scopus 로고    scopus 로고
    • Low level of response to alcohol as associated with serotonin transporter genotype and high alcohol intake in adolescents
    • A.S. Hinckers, M. Laucht, M.H. Schmidt, K.F. Mann, G. Schumann, and M.A. Schuckit Low level of response to alcohol as associated with serotonin transporter genotype and high alcohol intake in adolescents Biol Psychiatry 60 2006 282 287
    • (2006) Biol Psychiatry , vol.60 , pp. 282-287
    • Hinckers, A.S.1    Laucht, M.2    Schmidt, M.H.3    Mann, K.F.4    Schumann, G.5    Schuckit, M.A.6
  • 35
    • 0033106106 scopus 로고    scopus 로고
    • Selective genotyping for the role of 5-HT2A, 5-HT2C, and GABA alpha 6 receptors and the serotonin transporter in the level of response to alcohol: A pilot study
    • M.A. Schuckit, C. Mazzanti, T.L. Smith, U. Ahmed, M. Radel, and N. Iwata Selective genotyping for the role of 5-HT2A, 5-HT2C, and GABA alpha 6 receptors and the serotonin transporter in the level of response to alcohol: a pilot study Biol Psychiatry 45 1999 647 651
    • (1999) Biol Psychiatry , vol.45 , pp. 647-651
    • Schuckit, M.A.1    Mazzanti, C.2    Smith, T.L.3    Ahmed, U.4    Radel, M.5    Iwata, N.6
  • 36
    • 0029744877 scopus 로고    scopus 로고
    • Alcohol dependence: A commentary on mechanisms
    • P.L. Hoffman, and B. Tabakoff Alcohol dependence: a commentary on mechanisms Alcohol Alcohol 31 1996 333 340
    • (1996) Alcohol Alcohol , vol.31 , pp. 333-340
    • Hoffman, P.L.1    Tabakoff, B.2
  • 37
    • 0346335778 scopus 로고    scopus 로고
    • A central role of the BK potassium channel in behavioral responses to ethanol in C. elegans
    • A.G. Davies, J.T. Pierce-Shimomura, H. Kim, M.K. VanHoven, T.R. Thiele, and A. Bonci A central role of the BK potassium channel in behavioral responses to ethanol in C. elegans Cell 115 2003 655 666
    • (2003) Cell , vol.115 , pp. 655-666
    • Davies, A.G.1    Pierce-Shimomura, J.T.2    Kim, H.3    Vanhoven, M.K.4    Thiele, T.R.5    Bonci, A.6
  • 38
    • 24144456193 scopus 로고    scopus 로고
    • Genetic associations of alcohol dehydrogenase with alcohol use disorders and endophenotypes in white college students
    • T.L. Wall, S.H. Shea, S.E. Luczak, T.A. Cook, and L.G. Carr Genetic associations of alcohol dehydrogenase with alcohol use disorders and endophenotypes in white college students J Abnorm Psychol 114 2005 456 465
    • (2005) J Abnorm Psychol , vol.114 , pp. 456-465
    • Wall, T.L.1    Shea, S.H.2    Luczak, S.E.3    Cook, T.A.4    Carr, L.G.5
  • 40
    • 33747675436 scopus 로고    scopus 로고
    • Associations of variations in alcohol dehydrogenase genes with the level of response to alcohol in non-Asians
    • N.C. Duranceaux, M.A. Schuckit, M.Y. Eng, S.K. Robinson, L.G. Carr, and T.L. Wall Associations of variations in alcohol dehydrogenase genes with the level of response to alcohol in non-Asians Alcohol Clin Exp Res 30 2006 1470 1478
    • (2006) Alcohol Clin Exp Res , vol.30 , pp. 1470-1478
    • Duranceaux, N.C.1    Schuckit, M.A.2    Eng, M.Y.3    Robinson, S.K.4    Carr, L.G.5    Wall, T.L.6
  • 41
    • 0032736548 scopus 로고    scopus 로고
    • Genetics of alcoholism: A review of recent studies in human and animal models
    • T. Foroud, and T.K. Li Genetics of alcoholism: a review of recent studies in human and animal models Am J Addict 8 1999 261 278
    • (1999) Am J Addict , vol.8 , pp. 261-278
    • Foroud, T.1    Li, T.K.2
  • 42
    • 27644552815 scopus 로고    scopus 로고
    • The neuroscience of addiction
    • N. Volkow, and T.K. Li The neuroscience of addiction Nat Neurosci 8 2005 1429 1430
    • (2005) Nat Neurosci , vol.8 , pp. 1429-1430
    • Volkow, N.1    Li, T.K.2
  • 43
    • 67649985942 scopus 로고    scopus 로고
    • Alcoholism: A systems approach from molecular physiology to addictive behavior
    • R. Spanagel Alcoholism: a systems approach from molecular physiology to addictive behavior Physiol Rev 89 2009 649 705
    • (2009) Physiol Rev , vol.89 , pp. 649-705
    • Spanagel, R.1
  • 44
    • 79957634943 scopus 로고
    • Task Force on DSM-IV
    • American Psychiatric Association Washington, DC
    • American Psychiatric Association Task Force on DSM-IV Diagnostic and Statistical Manual of Mental Disorders: DSM-IV 1994 American Psychiatric Association Washington, DC xxvii 886pp
    • (1994) Diagnostic and Statistical Manual of Mental Disorders: DSM-IV
  • 45
    • 0033553203 scopus 로고    scopus 로고
    • Pharmacological treatment of alcohol dependence: A review of the evidence
    • J.C. Garbutt, S.L. West, T.S. Carey, K.N. Lohr, and F.T. Crews Pharmacological treatment of alcohol dependence: a review of the evidence JAMA 281 1999 1318 1325
    • (1999) JAMA , vol.281 , pp. 1318-1325
    • Garbutt, J.C.1    West, S.L.2    Carey, T.S.3    Lohr, K.N.4    Crews, F.T.5
  • 46
    • 33746325472 scopus 로고    scopus 로고
    • Pharmacological treatment of alcohol dependence: Target symptoms and target mechanisms
    • M. Heilig, and M. Egli Pharmacological treatment of alcohol dependence: target symptoms and target mechanisms Pharmacol Ther 111 2006 855 876
    • (2006) Pharmacol Ther , vol.111 , pp. 855-876
    • Heilig, M.1    Egli, M.2
  • 47
    • 33646178951 scopus 로고    scopus 로고
    • Combined pharmacotherapies and behavioral interventions for alcohol dependence: The COMBINE study: A randomized controlled trial
    • R.F. Anton, S.S. O'Malley, D.A. Ciraulo, R.A. Cisler, D. Couper, and D.M. Donovan Combined pharmacotherapies and behavioral interventions for alcohol dependence: the COMBINE study: a randomized controlled trial JAMA 295 2006 2003 2017
    • (2006) JAMA , vol.295 , pp. 2003-2017
    • Anton, R.F.1    O'Malley, S.S.2    Ciraulo, D.A.3    Cisler, R.A.4    Couper, D.5    Donovan, D.M.6
  • 48
    • 77955632266 scopus 로고    scopus 로고
    • Turning the clock ahead: Potential preclinical and clinical neuropharmacological targets for alcohol dependence
    • L. Leggio, S. Cardone, A. Ferrulli, G.A. Kenna, M. Diana, and R.M. Swift Turning the clock ahead: potential preclinical and clinical neuropharmacological targets for alcohol dependence Curr Pharm Des 16 2010 2159 2181
    • (2010) Curr Pharm des , vol.16 , pp. 2159-2181
    • Leggio, L.1    Cardone, S.2    Ferrulli, A.3    Kenna, G.A.4    Diana, M.5    Swift, R.M.6
  • 49
    • 33847385403 scopus 로고    scopus 로고
    • Emerging approaches to managing alcohol dependence
    • R. Swift Emerging approaches to managing alcohol dependence Am J Health Syst Pharm 64 2007 S12 S22
    • (2007) Am J Health Syst Pharm , vol.64
    • Swift, R.1
  • 50
    • 36849082451 scopus 로고    scopus 로고
    • Update on neuropharmacological treatments for alcoholism: Scientific basis and clinical findings
    • B.A. Johnson Update on neuropharmacological treatments for alcoholism: scientific basis and clinical findings Biochem Pharmacol 75 2008 34 56
    • (2008) Biochem Pharmacol , vol.75 , pp. 34-56
    • Johnson, B.A.1
  • 51
    • 60249101338 scopus 로고    scopus 로고
    • The state of pharmacotherapy for the treatment of alcohol dependence
    • J.C. Garbutt The state of pharmacotherapy for the treatment of alcohol dependence J Subst Abuse Treat 36 2009 S15 S23 quiz S4S5
    • (2009) J Subst Abuse Treat , vol.36
    • Garbutt, J.C.1
  • 53
    • 39749095228 scopus 로고    scopus 로고
    • Insulin but not insulin growth factor-1 correlates with craving in currently drinking alcohol-dependent patients
    • L. Leggio, A. Ferrulli, N. Malandrino, A. Miceli, E. Capristo, and G. Gasbarrini Insulin but not insulin growth factor-1 correlates with craving in currently drinking alcohol-dependent patients Alcohol Clin Exp Res 32 2008 450 458
    • (2008) Alcohol Clin Exp Res , vol.32 , pp. 450-458
    • Leggio, L.1    Ferrulli, A.2    Malandrino, N.3    Miceli, A.4    Capristo, E.5    Gasbarrini, G.6
  • 54
    • 57249116913 scopus 로고    scopus 로고
    • Relationship between the hypothalamic-pituitary-thyroid axis and alcohol craving in alcohol-dependent patients: A longitudinal study
    • L. Leggio, A. Ferrulli, S. Cardone, N. Malandrino, A. Mirijello, and C. D'Angelo Relationship between the hypothalamic-pituitary-thyroid axis and alcohol craving in alcohol-dependent patients: a longitudinal study Alcohol Clin Exp Res 32 2008 2047 2053
    • (2008) Alcohol Clin Exp Res , vol.32 , pp. 2047-2053
    • Leggio, L.1    Ferrulli, A.2    Cardone, S.3    Malandrino, N.4    Mirijello, A.5    D'Angelo, C.6
  • 55
    • 77956040423 scopus 로고    scopus 로고
    • Ghrelin receptor antagonism decreases alcohol consumption and activation of perioculomotor urocortin-containing neurons
    • S. Kaur, and A.E. Ryabinin Ghrelin receptor antagonism decreases alcohol consumption and activation of perioculomotor urocortin-containing neurons Alcohol Clin Exp Res 34 2010 1525 1534
    • (2010) Alcohol Clin Exp Res , vol.34 , pp. 1525-1534
    • Kaur, S.1    Ryabinin, A.E.2
  • 56
    • 77953563389 scopus 로고    scopus 로고
    • Role of the ghrelin system in alcoholism: Acting on the growth hormone secretagogue receptor to treat alcohol-related diseases
    • L. Leggio Role of the ghrelin system in alcoholism: acting on the growth hormone secretagogue receptor to treat alcohol-related diseases Drug News Perspect 23 2010 157 166
    • (2010) Drug News Perspect , vol.23 , pp. 157-166
    • Leggio, L.1
  • 57
    • 77949877264 scopus 로고    scopus 로고
    • Aripiprazole: A drug with a novel mechanism of action and possible efficacy for alcohol dependence
    • D.E. Vergne, and R.F. Anton Aripiprazole: a drug with a novel mechanism of action and possible efficacy for alcohol dependence CNS Neurol Disord Drug Targets 9 2010 50 54
    • (2010) CNS Neurol Disord Drug Targets , vol.9 , pp. 50-54
    • Vergne, D.E.1    Anton, R.F.2
  • 58
    • 4444370811 scopus 로고    scopus 로고
    • Uses of topiramate in the treatment of alcohol dependence
    • B.A. Johnson Uses of topiramate in the treatment of alcohol dependence Expert Rev Neurother 4 2004 751 758
    • (2004) Expert Rev Neurother , vol.4 , pp. 751-758
    • Johnson, B.A.1
  • 59
    • 77955628606 scopus 로고    scopus 로고
    • Safety and efficacy of baclofen in the treatment of alcohol-dependent patients
    • G. Addolorato, and L. Leggio Safety and efficacy of baclofen in the treatment of alcohol-dependent patients Curr Pharm Des 16 2010 2113 2117
    • (2010) Curr Pharm des , vol.16 , pp. 2113-2117
    • Addolorato, G.1    Leggio, L.2
  • 60
    • 10844261674 scopus 로고    scopus 로고
    • Role of the serotonergic system in the neurobiology of alcoholism: Implications for treatment
    • B.A. Johnson Role of the serotonergic system in the neurobiology of alcoholism: implications for treatment CNS Drugs 18 2004 1105 1118
    • (2004) CNS Drugs , vol.18 , pp. 1105-1118
    • Johnson, B.A.1
  • 61
    • 77949905566 scopus 로고    scopus 로고
    • Neuronal nicotinic acetylcholine receptors as pharmacotherapeutic targets for the treatment of alcohol use disorders
    • S. Chatterjee, and S.E. Bartlett Neuronal nicotinic acetylcholine receptors as pharmacotherapeutic targets for the treatment of alcohol use disorders CNS Neurol Disord Drug Targets 9 2010 60 76
    • (2010) CNS Neurol Disord Drug Targets , vol.9 , pp. 60-76
    • Chatterjee, S.1    Bartlett, S.E.2
  • 62
    • 0013526775 scopus 로고    scopus 로고
    • Prediction of chemosensitivity for patients with acute myeloid leukemia, according to expression levels of 28 genes selected by genome-wide complementary DNA microarray analysis
    • J. Okutsu, T. Tsunoda, Y. Kaneta, T. Katagiri, O. Kitahara, and H. Zembutsu Prediction of chemosensitivity for patients with acute myeloid leukemia, according to expression levels of 28 genes selected by genome-wide complementary DNA microarray analysis Mol Cancer Ther 1 2002 1035 1042
    • (2002) Mol Cancer Ther , vol.1 , pp. 1035-1042
    • Okutsu, J.1    Tsunoda, T.2    Kaneta, Y.3    Katagiri, T.4    Kitahara, O.5    Zembutsu, H.6
  • 63
    • 0037081081 scopus 로고    scopus 로고
    • Genome-wide cDNA microarray screening to correlate gene expression profiles with sensitivity of 85 human cancer xenografts to anticancer drugs
    • H. Zembutsu, Y. Ohnishi, T. Tsunoda, Y. Furukawa, T. Katagiri, and Y. Ueyama Genome-wide cDNA microarray screening to correlate gene expression profiles with sensitivity of 85 human cancer xenografts to anticancer drugs Cancer Res 62 2002 518 527
    • (2002) Cancer Res , vol.62 , pp. 518-527
    • Zembutsu, H.1    Ohnishi, Y.2    Tsunoda, T.3    Furukawa, Y.4    Katagiri, T.5    Ueyama, Y.6
  • 64
    • 0042014485 scopus 로고    scopus 로고
    • Transcriptional profiling of targets for combination therapy of lung carcinoma with paclitaxel and mitogen-activated protein/extracellular signal-regulated kinase kinase inhibitor
    • D.J. Taxman, J.P. MacKeigan, C. Clements, D.T. Bergstralh, and J.P. Ting Transcriptional profiling of targets for combination therapy of lung carcinoma with paclitaxel and mitogen-activated protein/extracellular signal-regulated kinase kinase inhibitor Cancer Res 63 2003 5095 5104
    • (2003) Cancer Res , vol.63 , pp. 5095-5104
    • Taxman, D.J.1    MacKeigan, J.P.2    Clements, C.3    Bergstralh, D.T.4    Ting, J.P.5
  • 65
    • 0042852195 scopus 로고    scopus 로고
    • Proteomics in alcohol research
    • H. Anni, and Y. Israel Proteomics in alcohol research Alcohol Res Health 26 2002 219 232
    • (2002) Alcohol Res Health , vol.26 , pp. 219-232
    • Anni, H.1    Israel, Y.2
  • 67
    • 0344010009 scopus 로고    scopus 로고
    • Molecular analysis of transitional cell carcinoma using cDNA microarray
    • O. Mor, O. Nativ, A. Stein, L. Novak, D. Lehavi, and Y. Shiboleth Molecular analysis of transitional cell carcinoma using cDNA microarray Oncogene 22 2003 7702 7710
    • (2003) Oncogene , vol.22 , pp. 7702-7710
    • Mor, O.1    Nativ, O.2    Stein, A.3    Novak, L.4    Lehavi, D.5    Shiboleth, Y.6
  • 68
    • 0345868259 scopus 로고    scopus 로고
    • A diagnostic test for prostate cancer from gene expression profiling data
    • R. Bueno, K.R. Loughlin, M.H. Powell, and G.J. Gordon A diagnostic test for prostate cancer from gene expression profiling data J Urol 171 2004 903 906
    • (2004) J Urol , vol.171 , pp. 903-906
    • Bueno, R.1    Loughlin, K.R.2    Powell, M.H.3    Gordon, G.J.4
  • 69
    • 0033637841 scopus 로고    scopus 로고
    • Molecular characterization of schizophrenia viewed by microarray analysis of gene expression in prefrontal cortex
    • K. Mirnics, F.A. Middleton, A. Marquez, D.A. Lewis, and P. Levitt Molecular characterization of schizophrenia viewed by microarray analysis of gene expression in prefrontal cortex Neuron 28 2000 53 67
    • (2000) Neuron , vol.28 , pp. 53-67
    • Mirnics, K.1    Middleton, F.A.2    Marquez, A.3    Lewis, D.A.4    Levitt, P.5
  • 70
    • 0042011475 scopus 로고    scopus 로고
    • DNA microarrays: Translation of the genome from laboratory to clinic
    • D.H. Geschwind DNA microarrays: translation of the genome from laboratory to clinic Lancet Neurol 2 2003 275 282
    • (2003) Lancet Neurol , vol.2 , pp. 275-282
    • Geschwind, D.H.1
  • 71
    • 0141785242 scopus 로고    scopus 로고
    • CDNA microarray and proteomic approaches in the study of brain diseases: Focus on schizophrenia and Alzheimer's disease
    • E.R. Marcotte, L.K. Srivastava, and R. Quirion cDNA microarray and proteomic approaches in the study of brain diseases: focus on schizophrenia and Alzheimer's disease Pharmacol Ther 100 2003 63 74
    • (2003) Pharmacol Ther , vol.100 , pp. 63-74
    • Marcotte, E.R.1    Srivastava, L.K.2    Quirion, R.3
  • 73
    • 77952912527 scopus 로고    scopus 로고
    • Future prospects for biomarkers of alcohol consumption and alcohol-induced disorders
    • W.M. Freeman, and K.E. Vrana Future prospects for biomarkers of alcohol consumption and alcohol-induced disorders Alcohol Clin Exp Res 34 2010 946 954
    • (2010) Alcohol Clin Exp Res , vol.34 , pp. 946-954
    • Freeman, W.M.1    Vrana, K.E.2
  • 74
    • 0030682474 scopus 로고    scopus 로고
    • Carbohydrate deficient transferrin in detecting relapse in alcohol dependence
    • C. Mitchell, D. Simpson, and J. Chick Carbohydrate deficient transferrin in detecting relapse in alcohol dependence Drug Alcohol Depend 48 1997 97 103
    • (1997) Drug Alcohol Depend , vol.48 , pp. 97-103
    • Mitchell, C.1    Simpson, D.2    Chick, J.3
  • 75
    • 0033768173 scopus 로고    scopus 로고
    • Genes and addiction
    • E.J. Nestler Genes and addiction Nat Genet 26 2000 277 281
    • (2000) Nat Genet , vol.26 , pp. 277-281
    • Nestler, E.J.1
  • 76
    • 36549012990 scopus 로고    scopus 로고
    • High-throughput genomic technology in research and clinical management of breast cancer. Plasma-based proteomics in early detection and therapy
    • M.A. Davis, and S. Hanash High-throughput genomic technology in research and clinical management of breast cancer. Plasma-based proteomics in early detection and therapy Breast Cancer Res 8 2006 217
    • (2006) Breast Cancer Res , vol.8 , pp. 217
    • Davis, M.A.1    Hanash, S.2
  • 77
    • 33749845827 scopus 로고    scopus 로고
    • Whole genome expression analysis for biologic rational pathway modeling: Application in cancer prognosis and therapy prediction
    • D. Kemming, U. Vogt, N. Tidow, C.M. Schlotter, H. Burger, and M.W. Helms Whole genome expression analysis for biologic rational pathway modeling: application in cancer prognosis and therapy prediction Mol Diagn Ther 10 2006 271 280
    • (2006) Mol Diagn Ther , vol.10 , pp. 271-280
    • Kemming, D.1    Vogt, U.2    Tidow, N.3    Schlotter, C.M.4    Burger, H.5    Helms, M.W.6
  • 79
    • 44849088394 scopus 로고    scopus 로고
    • New molecular assays for cancer diagnosis and targeted therapy
    • P. Lea, and M. Ling New molecular assays for cancer diagnosis and targeted therapy Curr Opin Mol Ther 10 2008 251 259
    • (2008) Curr Opin Mol Ther , vol.10 , pp. 251-259
    • Lea, P.1    Ling, M.2
  • 80
    • 27844556870 scopus 로고    scopus 로고
    • Convergent functional genomics: A Bayesian candidate gene identification approach for complex disorders
    • B. Bertsch, C.A. Ogden, K. Sidhu, H. Le-Niculescu, R. Kuczenski, and A.B. Niculescu Convergent functional genomics: a Bayesian candidate gene identification approach for complex disorders Methods 37 2005 274 279
    • (2005) Methods , vol.37 , pp. 274-279
    • Bertsch, B.1    Ogden, C.A.2    Sidhu, K.3    Le-Niculescu, H.4    Kuczenski, R.5    Niculescu, A.B.6
  • 81
    • 61649089088 scopus 로고    scopus 로고
    • Transcriptional vulnerability of brain regions in Alzheimer's disease and dementia
    • V. Haroutunian, P. Katsel, and J. Schmeidler Transcriptional vulnerability of brain regions in Alzheimer's disease and dementia Neurobiol Aging 30 2009 561 573
    • (2009) Neurobiol Aging , vol.30 , pp. 561-573
    • Haroutunian, V.1    Katsel, P.2    Schmeidler, J.3
  • 82
    • 70450223147 scopus 로고    scopus 로고
    • Analysis of gene expression in two large schizophrenia cohorts identifies multiple changes associated with nerve terminal function
    • P.R. Maycox, F. Kelly, A. Taylor, S. Bates, J. Reid, and R. Logendra Analysis of gene expression in two large schizophrenia cohorts identifies multiple changes associated with nerve terminal function Mol Psychiatry 14 2009 1083 1094
    • (2009) Mol Psychiatry , vol.14 , pp. 1083-1094
    • Maycox, P.R.1    Kelly, F.2    Taylor, A.3    Bates, S.4    Reid, J.5    Logendra, R.6
  • 83
    • 33745214876 scopus 로고    scopus 로고
    • Patterns of gene expression in the frontal cortex discriminate alcoholic from nonalcoholic individuals
    • J. Liu, J.M. Lewohl, R.A. Harris, V.R. Iyer, P.R. Dodd, and P.K. Randall Patterns of gene expression in the frontal cortex discriminate alcoholic from nonalcoholic individuals Neuropsychopharmacology 31 2006 1574 1582
    • (2006) Neuropsychopharmacology , vol.31 , pp. 1574-1582
    • Liu, J.1    Lewohl, J.M.2    Harris, R.A.3    Iyer, V.R.4    Dodd, P.R.5    Randall, P.K.6
  • 84
    • 0035363734 scopus 로고    scopus 로고
    • Identification of potential diagnostic markers of prostate cancer and prostatic intraepithelial neoplasia using cDNA microarray
    • J.H. Bull, G. Ellison, A. Patel, G. Muir, M. Walker, and M. Underwood Identification of potential diagnostic markers of prostate cancer and prostatic intraepithelial neoplasia using cDNA microarray Br J Cancer 84 2001 1512 1519
    • (2001) Br J Cancer , vol.84 , pp. 1512-1519
    • Bull, J.H.1    Ellison, G.2    Patel, A.3    Muir, G.4    Walker, M.5    Underwood, M.6
  • 85
    • 33748714310 scopus 로고    scopus 로고
    • Transcriptional profiling develops molecular signatures for ovarian tumors
    • D.I. Smith Transcriptional profiling develops molecular signatures for ovarian tumors Cytometry 47 2002 60 62
    • (2002) Cytometry , vol.47 , pp. 60-62
    • Smith, D.I.1
  • 86
    • 0038823525 scopus 로고    scopus 로고
    • The endophenotype concept in psychiatry: Etymology and strategic intentions
    • I.I. Gottesman, and T.D. Gould The endophenotype concept in psychiatry: etymology and strategic intentions Am J Psychiatry 160 2003 636 645
    • (2003) Am J Psychiatry , vol.160 , pp. 636-645
    • Gottesman, I.I.1    Gould, T.D.2
  • 87
    • 33749024625 scopus 로고    scopus 로고
    • Alcohol-related genes: Contributions from studies with genetically engineered mice
    • J.C. Crabbe, T.J. Phillips, R.A. Harris, M.A. Arends, and G.F. Koob Alcohol-related genes: contributions from studies with genetically engineered mice Addict Biol 11 2006 195 269
    • (2006) Addict Biol , vol.11 , pp. 195-269
    • Crabbe, J.C.1    Phillips, T.J.2    Harris, R.A.3    Arends, M.A.4    Koob, G.F.5
  • 88
    • 76749141396 scopus 로고    scopus 로고
    • A comparison of selected quantitative trait loci associated with alcohol use phenotypes in humans and mouse models
    • C.L. Ehlers, N.A. Walter, D.M. Dick, K.J. Buck, and J.C. Crabbe A comparison of selected quantitative trait loci associated with alcohol use phenotypes in humans and mouse models Addict Biol 15 2010 185 199
    • (2010) Addict Biol , vol.15 , pp. 185-199
    • Ehlers, C.L.1    Walter, N.A.2    Dick, D.M.3    Buck, K.J.4    Crabbe, J.C.5
  • 89
    • 0028670645 scopus 로고
    • D2 dopamine receptor TaqI A alleles in medically ill alcoholic and nonalcoholic patients
    • E.P. Noble, K. Syndulko, R.J. Fitch, T. Ritchie, M.C. Bohlman, and P. Guth D2 dopamine receptor TaqI A alleles in medically ill alcoholic and nonalcoholic patients Alcohol Alcohol 29 1994 729 744
    • (1994) Alcohol Alcohol , vol.29 , pp. 729-744
    • Noble, E.P.1    Syndulko, K.2    Fitch, R.J.3    Ritchie, T.4    Bohlman, M.C.5    Guth, P.6
  • 91
    • 78650005651 scopus 로고    scopus 로고
    • The complexity of alcohol drinking: Studies in rodent genetic models
    • J.C. Crabbe, T.J. Phillips, and J.K. Belknap The complexity of alcohol drinking: studies in rodent genetic models Behav Genet 2010 (Epub ahead of print)
    • (2010) Behav Genet
    • Crabbe, J.C.1    Phillips, T.J.2    Belknap, J.K.3
  • 92
    • 60249096629 scopus 로고    scopus 로고
    • An overview of genetic influences in alcoholism
    • M.A. Schuckit An overview of genetic influences in alcoholism J Subst Abuse Treat 36 2009 S5 S14
    • (2009) J Subst Abuse Treat , vol.36
    • Schuckit, M.A.1
  • 93
    • 76749122845 scopus 로고    scopus 로고
    • Consilience of rodent and human phenotypes relevant for alcohol dependence
    • J.C. Crabbe Consilience of rodent and human phenotypes relevant for alcohol dependence Addict Biol 15 2010 103 108
    • (2010) Addict Biol , vol.15 , pp. 103-108
    • Crabbe, J.C.1
  • 94
    • 76749084324 scopus 로고    scopus 로고
    • Human and laboratory rodent low response to alcohol: Is better consilience possible?
    • J.C. Crabbe, R.L. Bell, and C.L. Ehlers Human and laboratory rodent low response to alcohol: is better consilience possible? Addict Biol 15 2010 125 144
    • (2010) Addict Biol , vol.15 , pp. 125-144
    • Crabbe, J.C.1    Bell, R.L.2    Ehlers, C.L.3
  • 95
    • 76749168547 scopus 로고    scopus 로고
    • Understanding the construct of impulsivity and its relationship to alcohol use disorders
    • D.M. Dick, G. Smith, P. Olausson, S.H. Mitchell, R.F. Leeman, and S.S. O'Malley Understanding the construct of impulsivity and its relationship to alcohol use disorders Addict Biol 15 2010 217 226
    • (2010) Addict Biol , vol.15 , pp. 217-226
    • Dick, D.M.1    Smith, G.2    Olausson, P.3    Mitchell, S.H.4    Leeman, R.F.5    O'Malley, S.S.6
  • 96
    • 76749117168 scopus 로고    scopus 로고
    • Acute withdrawal, protracted abstinence and negative affect in alcoholism: Are they linked?
    • M. Heilig, M. Egli, J.C. Crabbe, and H.C. Becker Acute withdrawal, protracted abstinence and negative affect in alcoholism: are they linked? Addict Biol 15 2010 169 184
    • (2010) Addict Biol , vol.15 , pp. 169-184
    • Heilig, M.1    Egli, M.2    Crabbe, J.C.3    Becker, H.C.4
  • 97
    • 76749157203 scopus 로고    scopus 로고
    • Ethanol consumption: How should we measure it? Achieving consilience between human and animal phenotypes
    • R.F. Leeman, M. Heilig, C.L. Cunningham, D.N. Stephens, T. Duka, and S.S. O'Malley Ethanol consumption: how should we measure it? Achieving consilience between human and animal phenotypes Addict Biol 15 2010 109 124
    • (2010) Addict Biol , vol.15 , pp. 109-124
    • Leeman, R.F.1    Heilig, M.2    Cunningham, C.L.3    Stephens, D.N.4    Duka, T.5    O'Malley, S.S.6
  • 98
    • 76749131142 scopus 로고    scopus 로고
    • Consilient research approaches in studying gene x environment interactions in alcohol research
    • K.J. Sher, D.M. Dick, J.C. Crabbe, K.E. Hutchison, S.S. O'Malley, and A.C. Heath Consilient research approaches in studying gene x environment interactions in alcohol research Addict Biol 15 2010 200 216
    • (2010) Addict Biol , vol.15 , pp. 200-216
    • Sher, K.J.1    Dick, D.M.2    Crabbe, J.C.3    Hutchison, K.E.4    O'Malley, S.S.5    Heath, A.C.6
  • 99
    • 76749086579 scopus 로고    scopus 로고
    • Reward sensitivity: Issues of measurement, and achieving consilience between human and animal phenotypes
    • D.N. Stephens, T. Duka, H.S. Crombag, C.L. Cunningham, M. Heilig, and J.C. Crabbe Reward sensitivity: issues of measurement, and achieving consilience between human and animal phenotypes Addict Biol 15 2010 145 168
    • (2010) Addict Biol , vol.15 , pp. 145-168
    • Stephens, D.N.1    Duka, T.2    Crombag, H.S.3    Cunningham, C.L.4    Heilig, M.5    Crabbe, J.C.6
  • 100
    • 34247847741 scopus 로고    scopus 로고
    • The genetics of alcoholism: Identifying specific genes through family studies
    • H.J. Edenberg, and T. Foroud The genetics of alcoholism: identifying specific genes through family studies Addict Biol 11 2006 386 396
    • (2006) Addict Biol , vol.11 , pp. 386-396
    • Edenberg, H.J.1    Foroud, T.2
  • 101
    • 0036598330 scopus 로고    scopus 로고
    • Complex-trait genetics: Emergence of multivariate strategies
    • T.J. Phillips, and J.K. Belknap Complex-trait genetics: emergence of multivariate strategies Nat Rev Neurosci 3 2002 478 485
    • (2002) Nat Rev Neurosci , vol.3 , pp. 478-485
    • Phillips, T.J.1    Belknap, J.K.2
  • 102
    • 67651108806 scopus 로고    scopus 로고
    • The genetics of quantitative traits: Challenges and prospects
    • T.F. Mackay, E.A. Stone, and J.F. Ayroles The genetics of quantitative traits: challenges and prospects Nat Rev Genet 10 2009 565 577
    • (2009) Nat Rev Genet , vol.10 , pp. 565-577
    • MacKay, T.F.1    Stone, E.A.2    Ayroles, J.F.3
  • 103
    • 0033118963 scopus 로고    scopus 로고
    • Identifying genes for alcohol and drug sensitivity: Recent progress and future directions
    • J.C. Crabbe, T.J. Phillips, K.J. Buck, C.L. Cunningham, and J.K. Belknap Identifying genes for alcohol and drug sensitivity: recent progress and future directions Trends Neurosci 22 1999 173 179
    • (1999) Trends Neurosci , vol.22 , pp. 173-179
    • Crabbe, J.C.1    Phillips, T.J.2    Buck, K.J.3    Cunningham, C.L.4    Belknap, J.K.5
  • 104
    • 0025326262 scopus 로고
    • Estimation of genetic correlation: Interpretation of experiments using selectively bred and inbred animals
    • J.C. Crabbe, T.J. Phillips, A. Kosobud, and J.K. Belknap Estimation of genetic correlation: interpretation of experiments using selectively bred and inbred animals Alcohol Clin Exp Res 14 1990 141 151
    • (1990) Alcohol Clin Exp Res , vol.14 , pp. 141-151
    • Crabbe, J.C.1    Phillips, T.J.2    Kosobud, A.3    Belknap, J.K.4
  • 105
    • 0031689868 scopus 로고    scopus 로고
    • Ethanol-induced conditioned taste aversion in BXD recombinant inbred mice
    • F.O. Risinger, and C.L. Cunningham Ethanol-induced conditioned taste aversion in BXD recombinant inbred mice Alcohol Clin Exp Res 22 1998 1234 1244
    • (1998) Alcohol Clin Exp Res , vol.22 , pp. 1234-1244
    • Risinger, F.O.1    Cunningham, C.L.2
  • 107
    • 33846503906 scopus 로고    scopus 로고
    • Quantitative trait locus mapping for acute functional tolerance to ethanol in the L x S recombinant inbred panel
    • B. Bennett, C. Downing, P. Carosone-Link, H. Ponicsan, C. Ruf, and T.E. Johnson Quantitative trait locus mapping for acute functional tolerance to ethanol in the L x S recombinant inbred panel Alcohol Clin Exp Res 31 2007 200 208
    • (2007) Alcohol Clin Exp Res , vol.31 , pp. 200-208
    • Bennett, B.1    Downing, C.2    Carosone-Link, P.3    Ponicsan, H.4    Ruf, C.5    Johnson, T.E.6
  • 108
    • 0036584950 scopus 로고    scopus 로고
    • Congenic mapping of alcohol and pentobarbital withdrawal liability loci to a < 1 centimorgan interval of murine chromosome 4: Identification of Mpdz as a candidate gene
    • C. Fehr, R.L. Shirley, J.K. Belknap, J.C. Crabbe, and K.J. Buck Congenic mapping of alcohol and pentobarbital withdrawal liability loci to a < 1 centimorgan interval of murine chromosome 4: identification of Mpdz as a candidate gene J Neurosci 22 2002 3730 3738
    • (2002) J Neurosci , vol.22 , pp. 3730-3738
    • Fehr, C.1    Shirley, R.L.2    Belknap, J.K.3    Crabbe, J.C.4    Buck, K.J.5
  • 110
    • 32144455860 scopus 로고    scopus 로고
    • Expression profiling identifies novel candidate genes for ethanol sensitivity QTLs
    • E.J. MacLaren, B. Bennett, T.E. Johnson, and J.M. Sikela Expression profiling identifies novel candidate genes for ethanol sensitivity QTLs Mamm Genome 17 2006 147 156
    • (2006) Mamm Genome , vol.17 , pp. 147-156
    • MacLaren, E.J.1    Bennett, B.2    Johnson, T.E.3    Sikela, J.M.4
  • 111
    • 33745214657 scopus 로고    scopus 로고
    • Candidate genes and their regulatory elements: Alcohol preference and tolerance
    • L. Saba, S.V. Bhave, N. Grahame, P. Bice, R. Lapadat, and J. Belknap Candidate genes and their regulatory elements: alcohol preference and tolerance Mamm Genome 17 2006 669 688
    • (2006) Mamm Genome , vol.17 , pp. 669-688
    • Saba, L.1    Bhave, S.V.2    Grahame, N.3    Bice, P.4    Lapadat, R.5    Belknap, J.6
  • 113
    • 33846158466 scopus 로고    scopus 로고
    • Defining the dopamine transporter proteome by convergent biochemical and in silico analyses
    • R. Maiya, I. Ponomarev, K.D. Linse, R.A. Harris, and R.D. Mayfield Defining the dopamine transporter proteome by convergent biochemical and in silico analyses Genes Brain Behav 6 2007 97 106
    • (2007) Genes Brain Behav , vol.6 , pp. 97-106
    • Maiya, R.1    Ponomarev, I.2    Linse, K.D.3    Harris, R.A.4    Mayfield, R.D.5
  • 114
    • 70349198891 scopus 로고    scopus 로고
    • Gene expression changes in the nucleus accumbens of alcohol-preferring rats following chronic ethanol consumption
    • R.L. Bell, M.W. Kimpel, J.N. McClintick, W.N. Strother, L.G. Carr, and T. Liang Gene expression changes in the nucleus accumbens of alcohol-preferring rats following chronic ethanol consumption Pharmacol Biochem Behav 94 2009 131 147
    • (2009) Pharmacol Biochem Behav , vol.94 , pp. 131-147
    • Bell, R.L.1    Kimpel, M.W.2    McClintick, J.N.3    Strother, W.N.4    Carr, L.G.5    Liang, T.6
  • 115
    • 77249167034 scopus 로고    scopus 로고
    • Changes in gene expression in regions of the extended amygdala of alcohol-preferring rats after binge-like alcohol drinking
    • W.J. McBride, M.W. Kimpel, J.A. Schultz, J.N. McClintick, H.J. Edenberg, and R.L. Bell Changes in gene expression in regions of the extended amygdala of alcohol-preferring rats after binge-like alcohol drinking Alcohol 44 2010 171 183
    • (2010) Alcohol , vol.44 , pp. 171-183
    • McBride, W.J.1    Kimpel, M.W.2    Schultz, J.A.3    McClintick, J.N.4    Edenberg, H.J.5    Bell, R.L.6
  • 116
    • 41949084152 scopus 로고    scopus 로고
    • Differential gene expression in the nucleus accumbens with ethanol self-administration in inbred alcohol-preferring rats
    • Z.A. Rodd, M.W. Kimpel, H.J. Edenberg, R.L. Bell, W.N. Strother, and J.N. McClintick Differential gene expression in the nucleus accumbens with ethanol self-administration in inbred alcohol-preferring rats Pharmacol Biochem Behav 89 2008 481 498
    • (2008) Pharmacol Biochem Behav , vol.89 , pp. 481-498
    • Rodd, Z.A.1    Kimpel, M.W.2    Edenberg, H.J.3    Bell, R.L.4    Strother, W.N.5    McClintick, J.N.6
  • 117
    • 0033675534 scopus 로고    scopus 로고
    • Expression profiling of neural cells reveals specific patterns of ethanol-responsive gene expression
    • C. Thibault, C. Lai, N. Wilke, B. Duong, M.F. Olive, and S. Rahman Expression profiling of neural cells reveals specific patterns of ethanol-responsive gene expression Mol Pharmacol 58 2000 1593 1600
    • (2000) Mol Pharmacol , vol.58 , pp. 1593-1600
    • Thibault, C.1    Lai, C.2    Wilke, N.3    Duong, B.4    Olive, M.F.5    Rahman, S.6
  • 118
    • 0034967563 scopus 로고    scopus 로고
    • Comparison of global brain gene expression profiles between inbred long-sleep and inbred short-sleep mice by high-density gene array hybridization
    • Y. Xu, M. Ehringer, F. Yang, and J.M. Sikela Comparison of global brain gene expression profiles between inbred long-sleep and inbred short-sleep mice by high-density gene array hybridization Alcohol Clin Exp Res 25 2001 810 818
    • (2001) Alcohol Clin Exp Res , vol.25 , pp. 810-818
    • Xu, Y.1    Ehringer, M.2    Yang, F.3    Sikela, J.M.4
  • 119
    • 0002221924 scopus 로고    scopus 로고
    • Expression profiling identifies strain-specific changes associated with ethanol withdrawal in mice
    • G.M. Daniels, and K.J. Buck Expression profiling identifies strain-specific changes associated with ethanol withdrawal in mice Genes Brain Behav 1 2002 35 45
    • (2002) Genes Brain Behav , vol.1 , pp. 35-45
    • Daniels, G.M.1    Buck, K.J.2
  • 120
    • 0036807224 scopus 로고    scopus 로고
    • Microarray analysis of gene expression in rat hippocampus after chronic ethanol treatment
    • M. Saito, J. Smiley, R. Toth, and C. Vadasz Microarray analysis of gene expression in rat hippocampus after chronic ethanol treatment Neurochem Res 27 2002 1221 1229
    • (2002) Neurochem Res , vol.27 , pp. 1221-1229
    • Saito, M.1    Smiley, J.2    Toth, R.3    Vadasz, C.4
  • 121
    • 0141643191 scopus 로고    scopus 로고
    • Pharmacogenomic analysis of mechanisms mediating ethanol regulation of dopamine beta-hydroxylase
    • S. Hassan, B. Duong, K.S. Kim, and M.F. Miles Pharmacogenomic analysis of mechanisms mediating ethanol regulation of dopamine beta-hydroxylase J Biol Chem 278 2003 38860 38869
    • (2003) J Biol Chem , vol.278 , pp. 38860-38869
    • Hassan, S.1    Duong, B.2    Kim, K.S.3    Miles, M.F.4
  • 122
    • 0037780558 scopus 로고    scopus 로고
    • Selective breeding, quantitative trait locus analysis, and gene arrays identify candidate genes for complex drug-related behaviors
    • B. Tabakoff, S.V. Bhave, and P.L. Hoffman Selective breeding, quantitative trait locus analysis, and gene arrays identify candidate genes for complex drug-related behaviors J Neurosci 23 2003 4491 4498
    • (2003) J Neurosci , vol.23 , pp. 4491-4498
    • Tabakoff, B.1    Bhave, S.V.2    Hoffman, P.L.3
  • 123
    • 3543022156 scopus 로고    scopus 로고
    • Mouse striatal transcriptome analysis: Effects of oral self-administration of alcohol
    • M. Saito, I. Szakall, R. Toth, K.M. Kovacs, M. Oros, and V.V. Prasad Mouse striatal transcriptome analysis: effects of oral self-administration of alcohol Alcohol 32 2004 223 241
    • (2004) Alcohol , vol.32 , pp. 223-241
    • Saito, M.1    Szakall, I.2    Toth, R.3    Kovacs, K.M.4    Oros, M.5    Prasad, V.V.6
  • 124
    • 1242269209 scopus 로고    scopus 로고
    • Microarray analysis of mouse brain gene expression following acute ethanol treatment
    • J.A. Treadwell, and S.M. Singh Microarray analysis of mouse brain gene expression following acute ethanol treatment Neurochem Res 29 2004 357 369
    • (2004) Neurochem Res , vol.29 , pp. 357-369
    • Treadwell, J.A.1    Singh, S.M.2
  • 125
    • 14644397886 scopus 로고    scopus 로고
    • Ethanol-responsive brain region expression networks: Implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice
    • R.T. Kerns, A. Ravindranathan, S. Hassan, M.P. Cage, T. York, and J.M. Sikela Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice J Neurosci 25 2005 2255 2266
    • (2005) J Neurosci , vol.25 , pp. 2255-2266
    • Kerns, R.T.1    Ravindranathan, A.2    Hassan, S.3    Cage, M.P.4    York, T.5    Sikela, J.M.6
  • 126
    • 1242338915 scopus 로고    scopus 로고
    • Alcoholism damages the brain, but does moderate alcohol use?
    • A. Pfefferbaum Alcoholism damages the brain, but does moderate alcohol use? Lancet Neurol 3 2004 143 144
    • (2004) Lancet Neurol , vol.3 , pp. 143-144
    • Pfefferbaum, A.1
  • 127
    • 24944442520 scopus 로고    scopus 로고
    • Neurocircuitry in alcoholism: A substrate of disruption and repair
    • E.V. Sullivan, and A. Pfefferbaum Neurocircuitry in alcoholism: a substrate of disruption and repair Psychopharmacology (Berl) 180 2005 583 594
    • (2005) Psychopharmacology (Berl) , vol.180 , pp. 583-594
    • Sullivan, E.V.1    Pfefferbaum, A.2
  • 128
    • 61449209903 scopus 로고    scopus 로고
    • The neuropathology of alcohol-related brain damage
    • C. Harper The neuropathology of alcohol-related brain damage Alcohol Alcohol 44 2009 136 140
    • (2009) Alcohol Alcohol , vol.44 , pp. 136-140
    • Harper, C.1
  • 130
    • 0036315907 scopus 로고    scopus 로고
    • Patterns of gene expression are altered in the frontal and motor cortices of human alcoholics
    • R.D. Mayfield, J.M. Lewohl, P.R. Dodd, A. Herlihy, J. Liu, and R.A. Harris Patterns of gene expression are altered in the frontal and motor cortices of human alcoholics J Neurochem 81 2002 802 813
    • (2002) J Neurochem , vol.81 , pp. 802-813
    • Mayfield, R.D.1    Lewohl, J.M.2    Dodd, P.R.3    Herlihy, A.4    Liu, J.5    Harris, R.A.6
  • 131
    • 4444356798 scopus 로고    scopus 로고
    • Gene expression profiling of individual cases reveals consistent transcriptional changes in alcoholic human brain
    • J. Liu, J.M. Lewohl, P.R. Dodd, P.K. Randall, R.A. Harris, and R.D. Mayfield Gene expression profiling of individual cases reveals consistent transcriptional changes in alcoholic human brain J Neurochem 90 2004 1050 1058
    • (2004) J Neurochem , vol.90 , pp. 1050-1058
    • Liu, J.1    Lewohl, J.M.2    Dodd, P.R.3    Randall, P.K.4    Harris, R.A.5    Mayfield, R.D.6
  • 133
    • 34548236356 scopus 로고    scopus 로고
    • Altered gene expression profiles in the frontal cortex of cirrhotic alcoholics
    • J. Liu, J.M. Lewohl, R.A. Harris, P.R. Dodd, and R.D. Mayfield Altered gene expression profiles in the frontal cortex of cirrhotic alcoholics Alcohol Clin Exp Res 31 2007 1460 1466
    • (2007) Alcohol Clin Exp Res , vol.31 , pp. 1460-1466
    • Liu, J.1    Lewohl, J.M.2    Harris, R.A.3    Dodd, P.R.4    Mayfield, R.D.5
  • 135
    • 2942716700 scopus 로고    scopus 로고
    • A cluster of differentially expressed signal transduction genes identified by microarray analysis in a rat genetic model of alcoholism
    • C. Arlinde, W. Sommer, K. Bjork, M. Reimers, P. Hyytia, and K. Kiianmaa A cluster of differentially expressed signal transduction genes identified by microarray analysis in a rat genetic model of alcoholism Pharmacogenomics J 4 2004 208 218
    • (2004) Pharmacogenomics J , vol.4 , pp. 208-218
    • Arlinde, C.1    Sommer, W.2    Bjork, K.3    Reimers, M.4    Hyytia, P.5    Kiianmaa, K.6
  • 138
    • 34248644018 scopus 로고    scopus 로고
    • Functional gene expression differences between inbred alcohol-preferring and -non-preferring rats in five brain regions
    • M.W. Kimpel, W.N. Strother, J.N. McClintick, L.G. Carr, T. Liang, and H.J. Edenberg Functional gene expression differences between inbred alcohol-preferring and -non-preferring rats in five brain regions Alcohol 41 2007 95 132
    • (2007) Alcohol , vol.41 , pp. 95-132
    • Kimpel, M.W.1    Strother, W.N.2    McClintick, J.N.3    Carr, L.G.4    Liang, T.5    Edenberg, H.J.6
  • 139
    • 40549144036 scopus 로고    scopus 로고
    • Neurotoxic consequences of chronic alcohol withdrawal: Expression profiling reveals importance of gender over withdrawal severity
    • J.G. Hashimoto, and K.M. Wiren Neurotoxic consequences of chronic alcohol withdrawal: expression profiling reveals importance of gender over withdrawal severity Neuropsychopharmacology 33 2008 1084 1096
    • (2008) Neuropsychopharmacology , vol.33 , pp. 1084-1096
    • Hashimoto, J.G.1    Wiren, K.M.2
  • 140
    • 0036136686 scopus 로고    scopus 로고
    • Long-lasting increase in voluntary ethanol consumption and transcriptional regulation in the rat brain after intermittent exposure to alcohol
    • R. Rimondini, C. Arlinde, W. Sommer, and M. Heilig Long-lasting increase in voluntary ethanol consumption and transcriptional regulation in the rat brain after intermittent exposure to alcohol FASEB J 16 2002 27 35
    • (2002) FASEB J , vol.16 , pp. 27-35
    • Rimondini, R.1    Arlinde, C.2    Sommer, W.3    Heilig, M.4
  • 141
    • 34547663607 scopus 로고    scopus 로고
    • Candidate genes, pathways and mechanisms for alcoholism: An expanded convergent functional genomics approach
    • Z.A. Rodd, B.A. Bertsch, W.N. Strother, H. Le-Niculescu, Y. Balaraman, and E. Hayden Candidate genes, pathways and mechanisms for alcoholism: an expanded convergent functional genomics approach Pharmacogenomics J 7 2007 222 256
    • (2007) Pharmacogenomics J , vol.7 , pp. 222-256
    • Rodd, Z.A.1    Bertsch, B.A.2    Strother, W.N.3    Le-Niculescu, H.4    Balaraman, Y.5    Hayden, E.6
  • 143
    • 70350087346 scopus 로고    scopus 로고
    • Synaptic proteome changes in the superior frontal gyrus and occipital cortex of the alcoholic brain
    • N. Etheridge, J.M. Lewohl, R.D. Mayfield, R.A. Harris, and P.R. Dodd Synaptic proteome changes in the superior frontal gyrus and occipital cortex of the alcoholic brain Proteomics Clin Appl 3 2009 730 742
    • (2009) Proteomics Clin Appl , vol.3 , pp. 730-742
    • Etheridge, N.1    Lewohl, J.M.2    Mayfield, R.D.3    Harris, R.A.4    Dodd, P.R.5
  • 144
    • 32844475666 scopus 로고    scopus 로고
    • Differential protein expression in the prefrontal white matter of human alcoholics: A proteomics study
    • K. Alexander-Kaufman, G. James, D. Sheedy, C. Harper, and I. Matsumoto Differential protein expression in the prefrontal white matter of human alcoholics: a proteomics study Mol Psychiatry 11 2006 56 65
    • (2006) Mol Psychiatry , vol.11 , pp. 56-65
    • Alexander-Kaufman, K.1    James, G.2    Sheedy, D.3    Harper, C.4    Matsumoto, I.5
  • 145
    • 33846187293 scopus 로고    scopus 로고
    • Differential protein expression in the corpus callosum (splenium) of human alcoholics: A proteomics study
    • M.A. Kashem, G. James, C. Harper, P. Wilce, and I. Matsumoto Differential protein expression in the corpus callosum (splenium) of human alcoholics: a proteomics study Neurochem Int 50 2007 450 459
    • (2007) Neurochem Int , vol.50 , pp. 450-459
    • Kashem, M.A.1    James, G.2    Harper, C.3    Wilce, P.4    Matsumoto, I.5
  • 148
    • 45849101228 scopus 로고    scopus 로고
    • Differential protein expression in the corpus callosum (genu) of human alcoholics
    • M.A. Kashem, C. Harper, and I. Matsumoto Differential protein expression in the corpus callosum (genu) of human alcoholics Neurochem Int 53 2008 1 11
    • (2008) Neurochem Int , vol.53 , pp. 1-11
    • Kashem, M.A.1    Harper, C.2    Matsumoto, I.3
  • 149
    • 61449261932 scopus 로고    scopus 로고
    • Proteomics approach in the study of the pathophysiology of alcohol-related brain damage
    • I. Matsumoto Proteomics approach in the study of the pathophysiology of alcohol-related brain damage Alcohol Alcohol 44 2009 171 176
    • (2009) Alcohol Alcohol , vol.44 , pp. 171-176
    • Matsumoto, I.1
  • 151
    • 33845204371 scopus 로고    scopus 로고
    • Protein expression changes in the nucleus accumbens and amygdala of inbred alcohol-preferring rats given either continuous or scheduled access to ethanol
    • R.L. Bell, M.W. Kimpel, Z.A. Rodd, W.N. Strother, F. Bai, and C.L. Peper Protein expression changes in the nucleus accumbens and amygdala of inbred alcohol-preferring rats given either continuous or scheduled access to ethanol Alcohol 40 2006 3 17
    • (2006) Alcohol , vol.40 , pp. 3-17
    • Bell, R.L.1    Kimpel, M.W.2    Rodd, Z.A.3    Strother, W.N.4    Bai, F.5    Peper, C.L.6
  • 152
    • 59649096975 scopus 로고    scopus 로고
    • Differential effects of ethanol in the nucleus accumbens shell of alcohol-preferring (P), alcohol-non-preferring (NP) and Wistar rats: A proteomics study
    • W.J. McBride, J.A. Schultz, M.W. Kimpel, J.N. McClintick, M. Wang, and J. You Differential effects of ethanol in the nucleus accumbens shell of alcohol-preferring (P), alcohol-non-preferring (NP) and Wistar rats: a proteomics study Pharmacol Biochem Behav 92 2009 304 313
    • (2009) Pharmacol Biochem Behav , vol.92 , pp. 304-313
    • McBride, W.J.1    Schultz, J.A.2    Kimpel, M.W.3    McClintick, J.N.4    Wang, M.5    You, J.6
  • 153
    • 10744228401 scopus 로고    scopus 로고
    • Effect of agonal and postmortem factors on gene expression profile: Quality control in microarray analyses of postmortem human brain
    • H. Tomita, M.P. Vawter, D.M. Walsh, S.J. Evans, P.V. Choudary, and J. Li Effect of agonal and postmortem factors on gene expression profile: quality control in microarray analyses of postmortem human brain Biol Psychiatry 55 2004 346 352
    • (2004) Biol Psychiatry , vol.55 , pp. 346-352
    • Tomita, H.1    Vawter, M.P.2    Walsh, D.M.3    Evans, S.J.4    Choudary, P.V.5    Li, J.6
  • 154
    • 27844592179 scopus 로고    scopus 로고
    • A microarray data analysis framework for postmortem tissues
    • E.S. Jackson, M.T. Wayland, W. Fitzgerald, and S. Bahn A microarray data analysis framework for postmortem tissues Methods 37 2005 247 260
    • (2005) Methods , vol.37 , pp. 247-260
    • Jackson, E.S.1    Wayland, M.T.2    Fitzgerald, W.3    Bahn, S.4
  • 155
    • 34249889834 scopus 로고    scopus 로고
    • Methodological considerations for gene expression profiling of human brain
    • M. Atz, D. Walsh, P. Cartagena, J. Li, S. Evans, and P. Choudary Methodological considerations for gene expression profiling of human brain J Neurosci Methods 163 2007 295 309
    • (2007) J Neurosci Methods , vol.163 , pp. 295-309
    • Atz, M.1    Walsh, D.2    Cartagena, P.3    Li, J.4    Evans, S.5    Choudary, P.6
  • 157
    • 1242341923 scopus 로고    scopus 로고
    • Incipient Alzheimer's disease: Microarray correlation analyses reveal major transcriptional and tumor suppressor responses
    • E.M. Blalock, J.W. Geddes, K.C. Chen, N.M. Porter, W.R. Markesbery, and P.W. Landfield Incipient Alzheimer's disease: microarray correlation analyses reveal major transcriptional and tumor suppressor responses Proc Natl Acad Sci USA 101 2004 2173 2178
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 2173-2178
    • Blalock, E.M.1    Geddes, J.W.2    Chen, K.C.3    Porter, N.M.4    Markesbery, W.R.5    Landfield, P.W.6
  • 158
    • 0036105484 scopus 로고    scopus 로고
    • Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis
    • C. Lock, G. Hermans, R. Pedotti, A. Brendolan, E. Schadt, and H. Garren Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis Nat Med 8 2002 500 508
    • (2002) Nat Med , vol.8 , pp. 500-508
    • Lock, C.1    Hermans, G.2    Pedotti, R.3    Brendolan, A.4    Schadt, E.5    Garren, H.6
  • 159
    • 33644817756 scopus 로고    scopus 로고
    • Mitochondrial dysfunction as a cause of axonal degeneration in multiple sclerosis patients
    • R. Dutta, J. McDonough, X. Yin, J. Peterson, A. Chang, and T. Torres Mitochondrial dysfunction as a cause of axonal degeneration in multiple sclerosis patients Ann Neurol 59 2006 478 489
    • (2006) Ann Neurol , vol.59 , pp. 478-489
    • Dutta, R.1    McDonough, J.2    Yin, X.3    Peterson, J.4    Chang, A.5    Torres, T.6
  • 160
    • 0035160042 scopus 로고    scopus 로고
    • Gene expression profiling in postmortem Rett Syndrome brain: Differential gene expression and patient classification
    • C. Colantuoni, O.H. Jeon, K. Hyder, A. Chenchik, A.H. Khimani, and V. Narayanan Gene expression profiling in postmortem Rett Syndrome brain: differential gene expression and patient classification Neurobiol Dis 8 2001 847 865
    • (2001) Neurobiol Dis , vol.8 , pp. 847-865
    • Colantuoni, C.1    Jeon, O.H.2    Hyder, K.3    Chenchik, A.4    Khimani, A.H.5    Narayanan, V.6
  • 162
    • 2042479398 scopus 로고    scopus 로고
    • Molecular characterization of bipolar disorder by comparing gene expression profiles of postmortem brains of major mental disorders
    • K. Iwamoto, C. Kakiuchi, M. Bundo, K. Ikeda, and T. Kato Molecular characterization of bipolar disorder by comparing gene expression profiles of postmortem brains of major mental disorders Mol Psychiatry 9 2004 406 416
    • (2004) Mol Psychiatry , vol.9 , pp. 406-416
    • Iwamoto, K.1    Kakiuchi, C.2    Bundo, M.3    Ikeda, K.4    Kato, T.5
  • 163
    • 0035426751 scopus 로고    scopus 로고
    • Analysis of complex brain disorders with gene expression microarrays: Schizophrenia as a disease of the synapse
    • K. Mirnics, F.A. Middleton, D.A. Lewis, and P. Levitt Analysis of complex brain disorders with gene expression microarrays: schizophrenia as a disease of the synapse Trends Neurosci 24 2001 479 486
    • (2001) Trends Neurosci , vol.24 , pp. 479-486
    • Mirnics, K.1    Middleton, F.A.2    Lewis, D.A.3    Levitt, P.4
  • 164
    • 10444287637 scopus 로고    scopus 로고
    • Heat shock protein 12A shows reduced expression in the prefrontal cortex of subjects with schizophrenia
    • J.L. Pongrac, F.A. Middleton, L. Peng, D.A. Lewis, P. Levitt, and K. Mirnics Heat shock protein 12A shows reduced expression in the prefrontal cortex of subjects with schizophrenia Biol Psychiatry 56 2004 943 950
    • (2004) Biol Psychiatry , vol.56 , pp. 943-950
    • Pongrac, J.L.1    Middleton, F.A.2    Peng, L.3    Lewis, D.A.4    Levitt, P.5    Mirnics, K.6
  • 165
    • 0035856428 scopus 로고    scopus 로고
    • Postmortem brain abnormalities of the glutamate neurotransmitter system in autism
    • A.E. Purcell, O.H. Jeon, A.W. Zimmerman, M.E. Blue, and J. Pevsner Postmortem brain abnormalities of the glutamate neurotransmitter system in autism Neurology 57 2001 1618 1628
    • (2001) Neurology , vol.57 , pp. 1618-1628
    • Purcell, A.E.1    Jeon, O.H.2    Zimmerman, A.W.3    Blue, M.E.4    Pevsner, J.5
  • 166
    • 0035380762 scopus 로고    scopus 로고
    • Microarrays in brain research: The good, the bad and the ugly
    • K. Mirnics Microarrays in brain research: the good, the bad and the ugly Nat Rev Neurosci 2 2001 444 447
    • (2001) Nat Rev Neurosci , vol.2 , pp. 444-447
    • Mirnics, K.1
  • 167
    • 0037644494 scopus 로고    scopus 로고
    • Transcription profiling reveals mitochondrial, ubiquitin and signaling systems abnormalities in postmortem brains from subjects with a history of alcohol abuse or dependence
    • B.P. Sokolov, L. Jiang, N.S. Trivedi, and C. Aston Transcription profiling reveals mitochondrial, ubiquitin and signaling systems abnormalities in postmortem brains from subjects with a history of alcohol abuse or dependence J Neurosci Res 72 2003 756 767
    • (2003) J Neurosci Res , vol.72 , pp. 756-767
    • Sokolov, B.P.1    Jiang, L.2    Trivedi, N.S.3    Aston, C.4
  • 168
    • 3242738202 scopus 로고    scopus 로고
    • Decreased expression of NEFH and PCP4/PEP19 in the prefrontal cortex of alcoholics
    • K. Iwamoto, M. Bundo, M. Yamamoto, H. Ozawa, T. Saito, and T. Kato Decreased expression of NEFH and PCP4/PEP19 in the prefrontal cortex of alcoholics Neurosci Res 49 2004 379 385
    • (2004) Neurosci Res , vol.49 , pp. 379-385
    • Iwamoto, K.1    Bundo, M.2    Yamamoto, M.3    Ozawa, H.4    Saito, T.5    Kato, T.6
  • 169
    • 0030763438 scopus 로고    scopus 로고
    • Novel decision making in patients with prefrontal or posterior brain damage
    • O. Godefroy, and M. Rousseaux Novel decision making in patients with prefrontal or posterior brain damage Neurology 49 1997 695 701
    • (1997) Neurology , vol.49 , pp. 695-701
    • Godefroy, O.1    Rousseaux, M.2
  • 170
    • 0032854149 scopus 로고    scopus 로고
    • Specific cognitive deficits in mild frontal variant frontotemporal dementia
    • S. Rahman, B.J. Sahakian, J.R. Hodges, R.D. Rogers, and T.W. Robbins Specific cognitive deficits in mild frontal variant frontotemporal dementia Brain 122 Pt 8 1999 1469 1493
    • (1999) Brain , vol.122 , Issue.PART 8 , pp. 1469-1493
    • Rahman, S.1    Sahakian, B.J.2    Hodges, J.R.3    Rogers, R.D.4    Robbins, T.W.5
  • 171
    • 0036110016 scopus 로고    scopus 로고
    • Chronic alcoholism and the frontal lobe: Which executive functions are imparied?
    • M.T. Ratti, P. Bo, A. Giardini, and D. Soragna Chronic alcoholism and the frontal lobe: which executive functions are imparied? Acta Neurol Scand 105 2002 276 281
    • (2002) Acta Neurol Scand , vol.105 , pp. 276-281
    • Ratti, M.T.1    Bo, P.2    Giardini, A.3    Soragna, D.4
  • 172
    • 0034748546 scopus 로고    scopus 로고
    • Drug addiction. Part II. Neurobiology of addiction
    • J. Vetulani Drug addiction. Part II. Neurobiology of addiction Pol J Pharmacol 53 2001 303 317
    • (2001) Pol J Pharmacol , vol.53 , pp. 303-317
    • Vetulani, J.1
  • 173
    • 0029116717 scopus 로고
    • Reduced activities of thiamine-dependent enzymes in brains of alcoholics in the absence of Wernicke's encephalopathy
    • J. Lavoie, and R.F. Butterworth Reduced activities of thiamine-dependent enzymes in brains of alcoholics in the absence of Wernicke's encephalopathy Alcohol Clin Exp Res 19 1995 1073 1077
    • (1995) Alcohol Clin Exp Res , vol.19 , pp. 1073-1077
    • Lavoie, J.1    Butterworth, R.F.2
  • 174
    • 0032981648 scopus 로고    scopus 로고
    • Adhesion molecule expression and regulation on cells of the central nervous system
    • S.J. Lee, and E.N. Benveniste Adhesion molecule expression and regulation on cells of the central nervous system J Neuroimmunol 98 1999 77 88
    • (1999) J Neuroimmunol , vol.98 , pp. 77-88
    • Lee, S.J.1    Benveniste, E.N.2
  • 175
    • 0036106017 scopus 로고    scopus 로고
    • The cadherin family of cell adhesion molecules: Multiple roles in synaptic plasticity
    • G.W. Huntley, O. Gil, and O. Bozdagi The cadherin family of cell adhesion molecules: multiple roles in synaptic plasticity Neuroscientist 8 2002 221 233
    • (2002) Neuroscientist , vol.8 , pp. 221-233
    • Huntley, G.W.1    Gil, O.2    Bozdagi, O.3
  • 176
    • 0036682158 scopus 로고    scopus 로고
    • The integrin family of cell adhesion molecules has multiple functions within the CNS
    • R. Milner, and I.L. Campbell The integrin family of cell adhesion molecules has multiple functions within the CNS J Neurosci Res 69 2002 286 291
    • (2002) J Neurosci Res , vol.69 , pp. 286-291
    • Milner, R.1    Campbell, I.L.2
  • 177
    • 0013500939 scopus 로고    scopus 로고
    • The cadherin superfamily in neural development: Diversity, function and interaction with other molecules
    • S. Hirano, S.T. Suzuki, and C. Redies The cadherin superfamily in neural development: diversity, function and interaction with other molecules Front Biosci 8 2003 d306 d355
    • (2003) Front Biosci , vol.8
    • Hirano, S.1    Suzuki, S.T.2    Redies, C.3
  • 178
    • 0038071095 scopus 로고    scopus 로고
    • Cell-cell signaling during synapse formation in the CNS
    • P. Scheiffele Cell-cell signaling during synapse formation in the CNS Annu Rev Neurosci 26 2003 485 508
    • (2003) Annu Rev Neurosci , vol.26 , pp. 485-508
    • Scheiffele, P.1
  • 179
    • 0021889216 scopus 로고
    • Brain shrinkage in chronic alcoholics: A pathological study
    • C.G. Harper, J.J. Kril, and R.L. Holloway Brain shrinkage in chronic alcoholics: a pathological study Br Med J (Clin Res Ed) 290 1985 501 504
    • (1985) Br Med J (Clin Res Ed) , vol.290 , pp. 501-504
    • Harper, C.G.1    Kril, J.J.2    Holloway, R.L.3
  • 180
    • 0024853708 scopus 로고
    • Neuronal counts from four cortical regions of alcoholic brains
    • J.J. Kril, and C.G. Harper Neuronal counts from four cortical regions of alcoholic brains Acta Neuropathol 79 1989 200 204
    • (1989) Acta Neuropathol , vol.79 , pp. 200-204
    • Kril, J.J.1    Harper, C.G.2
  • 182
    • 0026507628 scopus 로고
    • Drugs of abuse: Anatomy, pharmacology and function of reward pathways
    • G.F. Koob Drugs of abuse: anatomy, pharmacology and function of reward pathways Trends Pharmacol Sci 13 1992 177 184
    • (1992) Trends Pharmacol Sci , vol.13 , pp. 177-184
    • Koob, G.F.1
  • 184
    • 5444262536 scopus 로고    scopus 로고
    • Oxidative stress in the pathogenesis of hepatic encephalopathy
    • M.D. Norenberg, A.R. Jayakumar, and K.V. Rama Rao Oxidative stress in the pathogenesis of hepatic encephalopathy Metab Brain Dis 19 2004 313 329
    • (2004) Metab Brain Dis , vol.19 , pp. 313-329
    • Norenberg, M.D.1    Jayakumar, A.R.2    Rama Rao, K.V.3
  • 185
    • 35448969806 scopus 로고    scopus 로고
    • Neuronal cell death in hepatic encephalopathy
    • R.F. Butterworth Neuronal cell death in hepatic encephalopathy Metab Brain Dis 22 2007 309 320
    • (2007) Metab Brain Dis , vol.22 , pp. 309-320
    • Butterworth, R.F.1
  • 186
    • 77954143165 scopus 로고    scopus 로고
    • Evidence for oxidative/nitrosative stress in the pathogenesis of hepatic encephalopathy
    • C. Bemeur, P. Desjardins, and R.F. Butterworth Evidence for oxidative/nitrosative stress in the pathogenesis of hepatic encephalopathy Metab Brain Dis 25 2010 3 9
    • (2010) Metab Brain Dis , vol.25 , pp. 3-9
    • Bemeur, C.1    Desjardins, P.2    Butterworth, R.F.3
  • 187
    • 0036794922 scopus 로고    scopus 로고
    • Astrocyte modulation of neurotoxic injury
    • M. Aschner, U. Sonnewald, and K.H. Tan Astrocyte modulation of neurotoxic injury Brain Pathol 12 2002 475 481
    • (2002) Brain Pathol , vol.12 , pp. 475-481
    • Aschner, M.1    Sonnewald, U.2    Tan, K.H.3
  • 188
    • 33845198403 scopus 로고    scopus 로고
    • The alcohol-preferring P rat and animal models of excessive alcohol drinking
    • R.L. Bell, Z.A. Rodd, L. Lumeng, J.M. Murphy, and W.J. McBride The alcohol-preferring P rat and animal models of excessive alcohol drinking Addict Biol 11 2006 270 288
    • (2006) Addict Biol , vol.11 , pp. 270-288
    • Bell, R.L.1    Rodd, Z.A.2    Lumeng, L.3    Murphy, J.M.4    McBride, W.J.5
  • 189
    • 33847767498 scopus 로고    scopus 로고
    • Phenotypic characterization of genetically selected Sardinian alcohol-preferring (sP) and -non-preferring (sNP) rats
    • G. Colombo, C. Lobina, M.A. Carai, and G.L. Gessa Phenotypic characterization of genetically selected Sardinian alcohol-preferring (sP) and -non-preferring (sNP) rats Addict Biol 11 2006 324 338
    • (2006) Addict Biol , vol.11 , pp. 324-338
    • Colombo, G.1    Lobina, C.2    Carai, M.A.3    Gessa, G.L.4
  • 190
    • 34247884351 scopus 로고    scopus 로고
    • The UChA and UChB rat lines: Metabolic and genetic differences influencing ethanol intake
    • M.E. Quintanilla, Y. Israel, A. Sapag, and L. Tampier The UChA and UChB rat lines: metabolic and genetic differences influencing ethanol intake Addict Biol 11 2006 310 323
    • (2006) Addict Biol , vol.11 , pp. 310-323
    • Quintanilla, M.E.1    Israel, Y.2    Sapag, A.3    Tampier, L.4
  • 191
    • 34247869650 scopus 로고    scopus 로고
    • The alcohol-preferring AA and alcohol-avoiding ANA rats: Neurobiology of the regulation of alcohol drinking
    • W. Sommer, P. Hyytia, and K. Kiianmaa The alcohol-preferring AA and alcohol-avoiding ANA rats: neurobiology of the regulation of alcohol drinking Addict Biol 11 2006 289 309
    • (2006) Addict Biol , vol.11 , pp. 289-309
    • Sommer, W.1    Hyytia, P.2    Kiianmaa, K.3
  • 192
    • 0032104644 scopus 로고    scopus 로고
    • Genetics of alcohol and other abused drugs
    • J.C. Crabbe, and T.J. Phillips Genetics of alcohol and other abused drugs Drug Alcohol Depend 51 1998 61 71
    • (1998) Drug Alcohol Depend , vol.51 , pp. 61-71
    • Crabbe, J.C.1    Phillips, T.J.2
  • 194
    • 0023257348 scopus 로고
    • Neurogenetic adaptive mechanisms in alcoholism
    • C.R. Cloninger Neurogenetic adaptive mechanisms in alcoholism Science 236 1987 410 416
    • (1987) Science , vol.236 , pp. 410-416
    • Cloninger, C.R.1
  • 195
    • 0018361336 scopus 로고
    • The familial incidence of alcoholism: A review
    • N.S. Cotton The familial incidence of alcoholism: a review J Stud Alcohol 40 1979 89 116
    • (1979) J Stud Alcohol , vol.40 , pp. 89-116
    • Cotton, N.S.1
  • 196
    • 0022498111 scopus 로고
    • Genetic aspects of alcoholism
    • M.A. Schuckit Genetic aspects of alcoholism Ann Emerg Med 15 1986 991 996
    • (1986) Ann Emerg Med , vol.15 , pp. 991-996
    • Schuckit, M.A.1
  • 197
    • 0000610628 scopus 로고
    • Alcohol taste thresholds and concentrations of solution preferred by rats
    • C.P. Richter, and K.H. Campbell Alcohol taste thresholds and concentrations of solution preferred by rats Science 91 1940 507 508
    • (1940) Science , vol.91 , pp. 507-508
    • Richter, C.P.1    Campbell, K.H.2
  • 198
    • 0011003987 scopus 로고
    • Individual metabolic patterns, alcoholism, genetotrophic diseases
    • R.J. Williams, L.J. Berry, and E. Beerstecher Individual metabolic patterns, alcoholism, genetotrophic diseases Proc Natl Acad Sci USA 35 1949 265 271
    • (1949) Proc Natl Acad Sci USA , vol.35 , pp. 265-271
    • Williams, R.J.1    Berry, L.J.2    Beerstecher, E.3
  • 199
    • 0020581981 scopus 로고
    • Thirty-two years of selection of rats by ethanol preference: UChA and UChB strains
    • J. Mardones, and N. Segovia-Riquelme Thirty-two years of selection of rats by ethanol preference: UChA and UChB strains Neurobehav Toxicol Teratol 5 1983 171 178
    • (1983) Neurobehav Toxicol Teratol , vol.5 , pp. 171-178
    • Mardones, J.1    Segovia-Riquelme, N.2
  • 200
    • 0000007684 scopus 로고
    • Differences in alcohol preference among inbred strains of mice
    • G.E. McClearn, and D.A. Rodgers Differences in alcohol preference among inbred strains of mice Q J Stud Alcohol 20 1959 691 695
    • (1959) Q J Stud Alcohol , vol.20 , pp. 691-695
    • McClearn, G.E.1    Rodgers, D.A.2
  • 201
    • 33646293109 scopus 로고
    • Genetic factors in alcohol preference of laboratory mice
    • G.E. McClearn, and D.A. Rodgers Genetic factors in alcohol preference of laboratory mice J Comp Physiol Psychol 54 1961 116 119
    • (1961) J Comp Physiol Psychol , vol.54 , pp. 116-119
    • McClearn, G.E.1    Rodgers, D.A.2
  • 203
    • 0032982015 scopus 로고    scopus 로고
    • GABA(A) receptors modulate ethanol-induced conditioned place preference and taste aversion in mice
    • J.A. Chester, and C.L. Cunningham GABA(A) receptors modulate ethanol-induced conditioned place preference and taste aversion in mice Psychopharmacology (Berl) 144 1999 363 372
    • (1999) Psychopharmacology (Berl) , vol.144 , pp. 363-372
    • Chester, J.A.1    Cunningham, C.L.2
  • 204
    • 0033828903 scopus 로고    scopus 로고
    • Allelic variation in the GABA A receptor gamma2 subunit is associated with genetic susceptibility to ethanol-induced motor incoordination and hypothermia, conditioned taste aversion, and withdrawal in BXD/Ty recombinant inbred mice
    • H.M. Hood, and K.J. Buck Allelic variation in the GABA A receptor gamma2 subunit is associated with genetic susceptibility to ethanol-induced motor incoordination and hypothermia, conditioned taste aversion, and withdrawal in BXD/Ty recombinant inbred mice Alcohol Clin Exp Res 24 2000 1327 1334
    • (2000) Alcohol Clin Exp Res , vol.24 , pp. 1327-1334
    • Hood, H.M.1    Buck, K.J.2
  • 205
    • 18844454490 scopus 로고    scopus 로고
    • The syntaxin binding protein 1 gene (Stxbp1) is a candidate for an ethanol preference drinking locus on mouse chromosome 2
    • C. Fehr, R.L. Shirley, J.C. Crabbe, J.K. Belknap, K.J. Buck, and T.J. Phillips The syntaxin binding protein 1 gene (Stxbp1) is a candidate for an ethanol preference drinking locus on mouse chromosome 2 Alcohol Clin Exp Res 29 2005 708 720
    • (2005) Alcohol Clin Exp Res , vol.29 , pp. 708-720
    • Fehr, C.1    Shirley, R.L.2    Crabbe, J.C.3    Belknap, J.K.4    Buck, K.J.5    Phillips, T.J.6
  • 206
    • 33846429177 scopus 로고    scopus 로고
    • Sweet and bitter taste of ethanol in C57BL/6J and DBA2/J mouse strains
    • D.A. Blizard Sweet and bitter taste of ethanol in C57BL/6J and DBA2/J mouse strains Behav Genet 37 2007 146 159
    • (2007) Behav Genet , vol.37 , pp. 146-159
    • Blizard, D.A.1
  • 207
    • 0000906259 scopus 로고
    • Genetic selection for voluntary alcohol consumption in the albino rat
    • K. Eriksson Genetic selection for voluntary alcohol consumption in the albino rat Science 159 1968 739 741
    • (1968) Science , vol.159 , pp. 739-741
    • Eriksson, K.1
  • 208
    • 0000755097 scopus 로고
    • Finnish selection studies on alcohol-related behaviors: General outline
    • K. Eriksson, and M. Rusi Finnish selection studies on alcohol-related behaviors: general outline G.E. McClearn, R.A. Deitrich, V.G. Erwin, Development of Animal Models as Pharmacogenetic Tools 1981 U.S. Government Printing Office Washington, DC 87 117
    • (1981) Development of Animal Models As Pharmacogenetic Tools , pp. 87-117
    • Eriksson, K.1    Rusi, M.2
  • 209
    • 0024593736 scopus 로고
    • Genetic animal models in the study of alcoholism
    • J.C. Crabbe Genetic animal models in the study of alcoholism Alcohol Clin Exp Res 13 1989 120 127
    • (1989) Alcohol Clin Exp Res , vol.13 , pp. 120-127
    • Crabbe, J.C.1
  • 210
    • 0034566374 scopus 로고    scopus 로고
    • Recent animal models of alcoholism
    • R. Spanagel Recent animal models of alcoholism Alcohol Res Health 24 2000 124 131
    • (2000) Alcohol Res Health , vol.24 , pp. 124-131
    • Spanagel, R.1
  • 212
    • 4644292674 scopus 로고    scopus 로고
    • An efficient SNP system for mouse genome scanning and elucidating strain relationships
    • P.M. Petkov, Y. Ding, M.A. Cassell, W. Zhang, G. Wagner, and E.E. Sargent An efficient SNP system for mouse genome scanning and elucidating strain relationships Genome Res 14 2004 1806 1811
    • (2004) Genome Res , vol.14 , pp. 1806-1811
    • Petkov, P.M.1    Ding, Y.2    Cassell, M.A.3    Zhang, W.4    Wagner, G.5    Sargent, E.E.6
  • 213
    • 33750829156 scopus 로고    scopus 로고
    • Stability of inbred mouse strain differences in behavior and brain size between laboratories and across decades
    • D. Wahlsten, A. Bachmanov, D.A. Finn, and J.C. Crabbe Stability of inbred mouse strain differences in behavior and brain size between laboratories and across decades Proc Natl Acad Sci USA 103 2006 16364 16369
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 16364-16369
    • Wahlsten, D.1    Bachmanov, A.2    Finn, D.A.3    Crabbe, J.C.4
  • 215
  • 216
    • 0032466081 scopus 로고    scopus 로고
    • Animal models of alcoholism: Neurobiology of high alcohol-drinking behavior in rodents
    • W.J. McBride, and T.K. Li Animal models of alcoholism: neurobiology of high alcohol-drinking behavior in rodents Crit Rev Neurobiol 12 1998 339 369
    • (1998) Crit Rev Neurobiol , vol.12 , pp. 339-369
    • McBride, W.J.1    Li, T.K.2
  • 217
    • 0027324698 scopus 로고
    • Selective breeding for alcohol preference and associated responses
    • T.K. Li, L. Lumeng, and D.P. Doolittle Selective breeding for alcohol preference and associated responses Behav Genet 23 1993 163 170
    • (1993) Behav Genet , vol.23 , pp. 163-170
    • Li, T.K.1    Lumeng, L.2    Doolittle, D.P.3
  • 218
    • 0031179884 scopus 로고    scopus 로고
    • ESBRA-Nordmann 1996 Award Lecture: Ethanol drinking behaviour in Sardinian alcohol-preferring rats
    • G. Colombo ESBRA-Nordmann 1996 Award Lecture: ethanol drinking behaviour in Sardinian alcohol-preferring rats Alcohol Alcohol 32 1997 443 453
    • (1997) Alcohol Alcohol , vol.32 , pp. 443-453
    • Colombo, G.1
  • 219
    • 0036751424 scopus 로고    scopus 로고
    • Phenotypic and genotypic characterization of the Indiana University rat lines selectively bred for high and low alcohol preference
    • J.M. Murphy, R.B. Stewart, R.L. Bell, N.E. Badia-Elder, L.G. Carr, and W.J. McBride Phenotypic and genotypic characterization of the Indiana University rat lines selectively bred for high and low alcohol preference Behav Genet 32 2002 363 388
    • (2002) Behav Genet , vol.32 , pp. 363-388
    • Murphy, J.M.1    Stewart, R.B.2    Bell, R.L.3    Badia-Elder, N.E.4    Carr, L.G.5    McBride, W.J.6
  • 220
    • 3042694117 scopus 로고    scopus 로고
    • Large-scale meta-analysis of cancer microarray data identifies common transcriptional profiles of neoplastic transformation and progression
    • D.R. Rhodes, J. Yu, K. Shanker, N. Deshpande, R. Varambally, and D. Ghosh Large-scale meta-analysis of cancer microarray data identifies common transcriptional profiles of neoplastic transformation and progression Proc Natl Acad Sci USA 101 2004 9309 9314
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 9309-9314
    • Rhodes, D.R.1    Yu, J.2    Shanker, K.3    Deshpande, N.4    Varambally, R.5    Ghosh, D.6
  • 221
    • 0030043694 scopus 로고    scopus 로고
    • Identification of sex-specific quantitative trait loci controlling alcohol preference in C57BL/6 mice
    • J.A. Melo, J. Shendure, K. Pociask, and L.M. Silver Identification of sex-specific quantitative trait loci controlling alcohol preference in C57BL/6 mice Nat Genet 13 1996 147 153
    • (1996) Nat Genet , vol.13 , pp. 147-153
    • Melo, J.A.1    Shendure, J.2    Pociask, K.3    Silver, L.M.4
  • 222
    • 0030969246 scopus 로고    scopus 로고
    • Quantitative trait loci involved in genetic predisposition to acute alcohol withdrawal in mice
    • K.J. Buck, P. Metten, J.K. Belknap, and J.C. Crabbe Quantitative trait loci involved in genetic predisposition to acute alcohol withdrawal in mice J Neurosci 17 1997 3946 3955
    • (1997) J Neurosci , vol.17 , pp. 3946-3955
    • Buck, K.J.1    Metten, P.2    Belknap, J.K.3    Crabbe, J.C.4
  • 224
    • 0034892647 scopus 로고    scopus 로고
    • Further characterization and high-resolution mapping of quantitative trait loci for ethanol-induced locomotor activity
    • K. Demarest, J. Koyner, J. McCaughran Jr., L. Cipp, and R. Hitzemann Further characterization and high-resolution mapping of quantitative trait loci for ethanol-induced locomotor activity Behav Genet 31 2001 79 91
    • (2001) Behav Genet , vol.31 , pp. 79-91
    • Demarest, K.1    Koyner, J.2    McCaughran Jr., J.3    Cipp, L.4    Hitzemann, R.5
  • 225
    • 0035167107 scopus 로고    scopus 로고
    • The replicability of QTLs for murine alcohol preference drinking behavior across eight independent studies
    • J.K. Belknap, and A.L. Atkins The replicability of QTLs for murine alcohol preference drinking behavior across eight independent studies Mamm Genome 12 2001 893 899
    • (2001) Mamm Genome , vol.12 , pp. 893-899
    • Belknap, J.K.1    Atkins, A.L.2
  • 226
    • 0035204002 scopus 로고    scopus 로고
    • Differential expression of NPY and its receptors in alcohol-preferring AA and alcohol-avoiding ANA rats
    • L. Caberlotto, A. Thorsell, R. Rimondini, W. Sommer, P. Hyytia, and M. Heilig Differential expression of NPY and its receptors in alcohol-preferring AA and alcohol-avoiding ANA rats Alcohol Clin Exp Res 25 2001 1564 1569
    • (2001) Alcohol Clin Exp Res , vol.25 , pp. 1564-1569
    • Caberlotto, L.1    Thorsell, A.2    Rimondini, R.3    Sommer, W.4    Hyytia, P.5    Heilig, M.6
  • 227
    • 0035844013 scopus 로고    scopus 로고
    • Evidence for the ability of hippocampal neurons to develop acute tolerance to ethanol in behaving rats
    • N. Ludvig, M.A. George, H.M. Tang, R.A. Gonzales, and P.M. Bungay Evidence for the ability of hippocampal neurons to develop acute tolerance to ethanol in behaving rats Brain Res 900 2001 252 260
    • (2001) Brain Res , vol.900 , pp. 252-260
    • Ludvig, N.1    George, M.A.2    Tang, H.M.3    Gonzales, R.A.4    Bungay, P.M.5
  • 228
    • 0036891565 scopus 로고    scopus 로고
    • Examination of ethanol responsive liver and brain specific gene expression, in the mouse strains with variable ethanol preferences, using cDNA expression arrays
    • B.C. Murphy, T. Chiu, M. Harrison, R.K. Uddin, and S.M. Singh Examination of ethanol responsive liver and brain specific gene expression, in the mouse strains with variable ethanol preferences, using cDNA expression arrays Biochem Genet 40 2002 395 410
    • (2002) Biochem Genet , vol.40 , pp. 395-410
    • Murphy, B.C.1    Chiu, T.2    Harrison, M.3    Uddin, R.K.4    Singh, S.M.5
  • 229
    • 0035142459 scopus 로고    scopus 로고
    • Evidence for a gender-related effect of alcoholism on brain volumes
    • D. Hommer, R. Momenan, E. Kaiser, and R. Rawlings Evidence for a gender-related effect of alcoholism on brain volumes Am J Psychiatry 158 2001 198 204
    • (2001) Am J Psychiatry , vol.158 , pp. 198-204
    • Hommer, D.1    Momenan, R.2    Kaiser, E.3    Rawlings, R.4
  • 231
    • 0018583595 scopus 로고
    • Long-term ethanol administration methods for rats: Advantages of inhalation over intubation or liquid diets
    • J. Rogers, S.G. Wiener, and F.E. Bloom Long-term ethanol administration methods for rats: advantages of inhalation over intubation or liquid diets Behav Neural Biol 27 1979 466 486
    • (1979) Behav Neural Biol , vol.27 , pp. 466-486
    • Rogers, J.1    Wiener, S.G.2    Bloom, F.E.3
  • 232
    • 0034008709 scopus 로고    scopus 로고
    • Excessive ethanol drinking following a history of dependence: Animal model of allostasis
    • A.J. Roberts, C.J. Heyser, M. Cole, P. Griffin, and G.F. Koob Excessive ethanol drinking following a history of dependence: animal model of allostasis Neuropsychopharmacology 22 2000 581 594
    • (2000) Neuropsychopharmacology , vol.22 , pp. 581-594
    • Roberts, A.J.1    Heyser, C.J.2    Cole, M.3    Griffin, P.4    Koob, G.F.5
  • 233
    • 0030455947 scopus 로고    scopus 로고
    • Norepinephrine and serotonin receptors in the paraventricular nucleus interactively modulate ethanol consumption
    • C.W. Hodge, C.J. Slawecki, and A.S. Aiken Norepinephrine and serotonin receptors in the paraventricular nucleus interactively modulate ethanol consumption Alcohol Clin Exp Res 20 1996 1669 1674
    • (1996) Alcohol Clin Exp Res , vol.20 , pp. 1669-1674
    • Hodge, C.W.1    Slawecki, C.J.2    Aiken, A.S.3
  • 234
    • 0034194187 scopus 로고    scopus 로고
    • Ethanol-associated behaviors of mice lacking norepinephrine
    • D. Weinshenker, N.C. Rust, N.S. Miller, and R.D. Palmiter Ethanol-associated behaviors of mice lacking norepinephrine J Neurosci 20 2000 3157 3164
    • (2000) J Neurosci , vol.20 , pp. 3157-3164
    • Weinshenker, D.1    Rust, N.C.2    Miller, N.S.3    Palmiter, R.D.4
  • 235
    • 0024300175 scopus 로고
    • Chronic ethanol causes heterologous desensitization of receptors by reducing alpha s messenger RNA
    • D. Mochly-Rosen, F.H. Chang, L. Cheever, M. Kim, I. Diamond, and A.S. Gordon Chronic ethanol causes heterologous desensitization of receptors by reducing alpha s messenger RNA Nature 333 1988 848 850
    • (1988) Nature , vol.333 , pp. 848-850
    • Mochly-Rosen, D.1    Chang, F.H.2    Cheever, L.3    Kim, M.4    Diamond, I.5    Gordon, A.S.6
  • 236
    • 0023808851 scopus 로고
    • Cultured lymphocytes from alcoholic subjects have altered cAMP signal transduction
    • L.E. Nagy, I. Diamond, and A. Gordon Cultured lymphocytes from alcoholic subjects have altered cAMP signal transduction Proc Natl Acad Sci USA 85 1988 6973 6976
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 6973-6976
    • Nagy, L.E.1    Diamond, I.2    Gordon, A.3
  • 238
    • 0032511188 scopus 로고    scopus 로고
    • Ethanol intoxication in Drosophila: Genetic and pharmacological evidence for regulation by the cAMP signaling pathway
    • M.S. Moore, J. DeZazzo, A.Y. Luk, T. Tully, C.M. Singh, and U. Heberlein Ethanol intoxication in Drosophila: genetic and pharmacological evidence for regulation by the cAMP signaling pathway Cell 93 1998 997 1007
    • (1998) Cell , vol.93 , pp. 997-1007
    • Moore, M.S.1    Dezazzo, J.2    Luk, A.Y.3    Tully, T.4    Singh, C.M.5    Heberlein, U.6
  • 239
    • 0034656653 scopus 로고    scopus 로고
    • High ethanol consumption and low sensitivity to ethanol-induced sedation in protein kinase A-mutant mice
    • T.E. Thiele, B. Willis, J. Stadler, J.G. Reynolds, I.L. Bernstein, and G.S. McKnight High ethanol consumption and low sensitivity to ethanol-induced sedation in protein kinase A-mutant mice J Neurosci 20 2000 RC75
    • (2000) J Neurosci , vol.20 , pp. 75
    • Thiele, T.E.1    Willis, B.2    Stadler, J.3    Reynolds, J.G.4    Bernstein, I.L.5    McKnight, G.S.6
  • 240
    • 0035879273 scopus 로고    scopus 로고
    • The cAMP-protein kinase A signal transduction pathway modulates ethanol consumption and sedative effects of ethanol
    • G. Wand, M. Levine, L. Zweifel, W. Schwindinger, and T. Abel The cAMP-protein kinase A signal transduction pathway modulates ethanol consumption and sedative effects of ethanol J Neurosci 21 2001 5297 5303
    • (2001) J Neurosci , vol.21 , pp. 5297-5303
    • Wand, G.1    Levine, M.2    Zweifel, L.3    Schwindinger, W.4    Abel, T.5
  • 241
    • 0037076671 scopus 로고    scopus 로고
    • Betagamma Dimers mediate synergy of dopamine D2 and adenosine A2 receptor-stimulated PKA signaling and regulate ethanol consumption
    • L. Yao, M.P. Arolfo, D.P. Dohrman, Z. Jiang, P. Fan, and S. Fuchs betagamma Dimers mediate synergy of dopamine D2 and adenosine A2 receptor-stimulated PKA signaling and regulate ethanol consumption Cell 109 2002 733 743
    • (2002) Cell , vol.109 , pp. 733-743
    • Yao, L.1    Arolfo, M.P.2    Dohrman, D.P.3    Jiang, Z.4    Fan, P.5    Fuchs, S.6
  • 245
    • 0032146540 scopus 로고    scopus 로고
    • Chronic ethanol feeding induces cellular antioxidants decrease and oxidative stress in rat peripheral nerves. Effect of S-adenosyl-L-methionine and N-acetyl-L-cysteine
    • F. Bosch-Morell, F. Martinez-Soriano, A. Colell, J.C. Fernandez-Checa, and F.J. Romero Chronic ethanol feeding induces cellular antioxidants decrease and oxidative stress in rat peripheral nerves. Effect of S-adenosyl-L-methionine and N-acetyl-L-cysteine Free Radic Biol Med 25 1998 365 368
    • (1998) Free Radic Biol Med , vol.25 , pp. 365-368
    • Bosch-Morell, F.1    Martinez-Soriano, F.2    Colell, A.3    Fernandez-Checa, J.C.4    Romero, F.J.5
  • 246
    • 39049191809 scopus 로고    scopus 로고
    • Exploration of human miRNA target genes in neuronal differentiation
    • Y. Fukuda, H. Kawasaki, and K. Taira Exploration of human miRNA target genes in neuronal differentiation Nucleic Acids Symp Ser (Oxf) 2005 341 342
    • (2005) Nucleic Acids Symp ser (Oxf) , pp. 341-342
    • Fukuda, Y.1    Kawasaki, H.2    Taira, K.3
  • 247
    • 70349312583 scopus 로고    scopus 로고
    • MicroRNA-125b promotes neuronal differentiation in human cells by repressing multiple targets
    • M.T. Le, H. Xie, B. Zhou, P.H. Chia, P. Rizk, and M. Um MicroRNA-125b promotes neuronal differentiation in human cells by repressing multiple targets Mol Cell Biol 29 2009 5290 5305
    • (2009) Mol Cell Biol , vol.29 , pp. 5290-5305
    • Le, M.T.1    Xie, H.2    Zhou, B.3    Chia, P.H.4    Rizk, P.5    Um, M.6
  • 248
    • 65349085532 scopus 로고    scopus 로고
    • MicroRNA-124: Micromanager of neurogenesis
    • T. Papagiannakopoulos, and K.S. Kosik MicroRNA-124: micromanager of neurogenesis Cell Stem Cell 4 2009 375 376
    • (2009) Cell Stem Cell , vol.4 , pp. 375-376
    • Papagiannakopoulos, T.1    Kosik, K.S.2
  • 249
    • 63649088898 scopus 로고    scopus 로고
    • Fine control: MicroRNA regulation of adult neurogenesis
    • Q. Shen, and S. Temple Fine control: microRNA regulation of adult neurogenesis Nat Neurosci 12 2009 369 370
    • (2009) Nat Neurosci , vol.12 , pp. 369-370
    • Shen, Q.1    Temple, S.2
  • 250
    • 47749120244 scopus 로고    scopus 로고
    • Posttranscriptional regulation of BK channel splice variant stability by miR-9 underlies neuroadaptation to alcohol
    • A.Z. Pietrzykowski, R.M. Friesen, G.E. Martin, S.I. Puig, C.L. Nowak, and P.M. Wynne Posttranscriptional regulation of BK channel splice variant stability by miR-9 underlies neuroadaptation to alcohol Neuron 59 2008 274 287
    • (2008) Neuron , vol.59 , pp. 274-287
    • Pietrzykowski, A.Z.1    Friesen, R.M.2    Martin, G.E.3    Puig, S.I.4    Nowak, C.L.5    Wynne, P.M.6
  • 251
    • 77951092028 scopus 로고    scopus 로고
    • Multiple microRNAs modulate p21Cip1/Waf1 expression by directly targeting its 3′ untranslated region
    • S. Wu, S. Huang, J. Ding, Y. Zhao, L. Liang, and T. Liu Multiple microRNAs modulate p21Cip1/Waf1 expression by directly targeting its 3′ untranslated region Oncogene 29 2010 2302 2308
    • (2010) Oncogene , vol.29 , pp. 2302-2308
    • Wu, S.1    Huang, S.2    Ding, J.3    Zhao, Y.4    Liang, L.5    Liu, T.6
  • 253
    • 67749132423 scopus 로고    scopus 로고
    • Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps
    • S.W. Chi, J.B. Zang, A. Mele, and R.B. Darnell Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps Nature 460 2009 479 486
    • (2009) Nature , vol.460 , pp. 479-486
    • Chi, S.W.1    Zang, J.B.2    Mele, A.3    Darnell, R.B.4
  • 255
    • 34547922786 scopus 로고    scopus 로고
    • Competing interactions between micro-RNAs determine neural progenitor survival and proliferation after ethanol exposure: Evidence from an ex vivo model of the fetal cerebral cortical neuroepithelium
    • P. Sathyan, H.B. Golden, and R.C. Miranda Competing interactions between micro-RNAs determine neural progenitor survival and proliferation after ethanol exposure: evidence from an ex vivo model of the fetal cerebral cortical neuroepithelium J Neurosci 27 2007 8546 8557
    • (2007) J Neurosci , vol.27 , pp. 8546-8557
    • Sathyan, P.1    Golden, H.B.2    Miranda, R.C.3
  • 256
    • 38349109046 scopus 로고    scopus 로고
    • Effect of alcohol on miR-212 expression in intestinal epithelial cells and its potential role in alcoholic liver disease
    • Y. Tang, A. Banan, C.B. Forsyth, J.Z. Fields, C.K. Lau, and L.J. Zhang Effect of alcohol on miR-212 expression in intestinal epithelial cells and its potential role in alcoholic liver disease Alcohol Clin Exp Res 32 2008 355 364
    • (2008) Alcohol Clin Exp Res , vol.32 , pp. 355-364
    • Tang, Y.1    Banan, A.2    Forsyth, C.B.3    Fields, J.Z.4    Lau, C.K.5    Zhang, L.J.6
  • 257
    • 77954510708 scopus 로고    scopus 로고
    • Striatal microRNA controls cocaine intake through CREB signalling
    • J.A. Hollander, H.I. Im, A.L. Amelio, J. Kocerha, P. Bali, and Q. Lu Striatal microRNA controls cocaine intake through CREB signalling Nature 466 2010 197 202
    • (2010) Nature , vol.466 , pp. 197-202
    • Hollander, J.A.1    Im, H.I.2    Amelio, A.L.3    Kocerha, J.4    Bali, P.5    Lu, Q.6
  • 258
    • 34547629436 scopus 로고    scopus 로고
    • RNA editing of the microRNA-151 precursor blocks cleavage by the Dicer-TRBP complex
    • Y. Kawahara, B. Zinshteyn, T.P. Chendrimada, R. Shiekhattar, and K. Nishikura RNA editing of the microRNA-151 precursor blocks cleavage by the Dicer-TRBP complex EMBO Rep 8 2007 763 769
    • (2007) EMBO Rep , vol.8 , pp. 763-769
    • Kawahara, Y.1    Zinshteyn, B.2    Chendrimada, T.P.3    Shiekhattar, R.4    Nishikura, K.5
  • 259
    • 34250877841 scopus 로고    scopus 로고
    • A mammalian microRNA expression atlas based on small RNA library sequencing
    • P. Landgraf, M. Rusu, R. Sheridan, A. Sewer, N. Iovino, and A. Aravin A mammalian microRNA expression atlas based on small RNA library sequencing Cell 129 2007 1401 1414
    • (2007) Cell , vol.129 , pp. 1401-1414
    • Landgraf, P.1    Rusu, M.2    Sheridan, R.3    Sewer, A.4    Iovino, N.5    Aravin, A.6
  • 260
    • 41649106136 scopus 로고    scopus 로고
    • Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells
    • R.D. Morin, M.D. O'Connor, M. Griffith, F. Kuchenbauer, A. Delaney, and A.L. Prabhu Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells Genome Res 18 2008 610 621
    • (2008) Genome Res , vol.18 , pp. 610-621
    • Morin, R.D.1    O'Connor, M.D.2    Griffith, M.3    Kuchenbauer, F.4    Delaney, A.5    Prabhu, A.L.6
  • 261
    • 53649088131 scopus 로고    scopus 로고
    • Applications of next-generation sequencing technologies in functional genomics
    • O. Morozova, and M.A. Marra Applications of next-generation sequencing technologies in functional genomics Genomics 92 2008 255 264
    • (2008) Genomics , vol.92 , pp. 255-264
    • Morozova, O.1    Marra, M.A.2
  • 262
    • 67650394369 scopus 로고    scopus 로고
    • Transcriptome sequencing of the Microarray Quality Control (MAQC) RNA reference samples using next generation sequencing
    • S.P. Mane, C. Evans, K.L. Cooper, O.R. Crasta, O. Folkerts, and S.K. Hutchison Transcriptome sequencing of the Microarray Quality Control (MAQC) RNA reference samples using next generation sequencing BMC Genomics 10 2009 264
    • (2009) BMC Genomics , vol.10 , pp. 264
    • Mane, S.P.1    Evans, C.2    Cooper, K.L.3    Crasta, O.R.4    Folkerts, O.5    Hutchison, S.K.6
  • 264
    • 70349162750 scopus 로고    scopus 로고
    • High throughput sequencing in mice: A platform comparison identifies a preponderance of cryptic SNPs
    • N.A. Walter, D. Bottomly, T. Laderas, M.A. Mooney, P. Darakjian, and R.P. Searles High throughput sequencing in mice: a platform comparison identifies a preponderance of cryptic SNPs BMC Genomics 10 2009 379
    • (2009) BMC Genomics , vol.10 , pp. 379
    • Walter, N.A.1    Bottomly, D.2    Laderas, T.3    Mooney, M.A.4    Darakjian, P.5    Searles, R.P.6
  • 266
    • 42049098607 scopus 로고    scopus 로고
    • Accumbens Homer2 overexpression facilitates alcohol-induced neuroplasticity in C57BL/6J mice
    • K.K. Szumlinski, A.W. Ary, K.D. Lominac, M. Klugmann, and T.E. Kippin Accumbens Homer2 overexpression facilitates alcohol-induced neuroplasticity in C57BL/6J mice Neuropsychopharmacology 33 2008 1365 1378
    • (2008) Neuropsychopharmacology , vol.33 , pp. 1365-1378
    • Szumlinski, K.K.1    Ary, A.W.2    Lominac, K.D.3    Klugmann, M.4    Kippin, T.E.5
  • 267
    • 36849090854 scopus 로고    scopus 로고
    • Homers regulate drug-induced neuroplasticity: Implications for addiction
    • K.K. Szumlinski, A.W. Ary, and K.D. Lominac Homers regulate drug-induced neuroplasticity: implications for addiction Biochem Pharmacol 75 2008 112 133
    • (2008) Biochem Pharmacol , vol.75 , pp. 112-133
    • Szumlinski, K.K.1    Ary, A.W.2    Lominac, K.D.3
  • 268
    • 70350507405 scopus 로고    scopus 로고
    • Differential effects of chronic ethanol consumption and withdrawal on homer/glutamate receptor expression in subregions of the accumbens and amygdala of P rats
    • I. Obara, R.L. Bell, S.P. Goulding, C.M. Reyes, L.A. Larson, and A.W. Ary Differential effects of chronic ethanol consumption and withdrawal on homer/glutamate receptor expression in subregions of the accumbens and amygdala of P rats Alcohol Clin Exp Res 33 2009 1924 1934
    • (2009) Alcohol Clin Exp Res , vol.33 , pp. 1924-1934
    • Obara, I.1    Bell, R.L.2    Goulding, S.P.3    Reyes, C.M.4    Larson, L.A.5    Ary, A.W.6
  • 269
    • 67650444731 scopus 로고    scopus 로고
    • Binge drinking upregulates accumbens mGluR5-Homer2-PI3K signaling: Functional implications for alcoholism
    • D.K. Cozzoli, S.P. Goulding, P.W. Zhang, B. Xiao, J.H. Hu, and A.W. Ary Binge drinking upregulates accumbens mGluR5-Homer2-PI3K signaling: functional implications for alcoholism J Neurosci 29 2009 8655 8668
    • (2009) J Neurosci , vol.29 , pp. 8655-8668
    • Cozzoli, D.K.1    Goulding, S.P.2    Zhang, P.W.3    Xiao, B.4    Hu, J.H.5    Ary, A.W.6
  • 270
    • 0342748583 scopus 로고    scopus 로고
    • Sequential steps in clathrin-mediated synaptic vesicle endocytosis
    • L. Brodin, P. Low, and O. Shupliakov Sequential steps in clathrin-mediated synaptic vesicle endocytosis Curr Opin Neurobiol 10 2000 312 320
    • (2000) Curr Opin Neurobiol , vol.10 , pp. 312-320
    • Brodin, L.1    Low, P.2    Shupliakov, O.3
  • 271
    • 0030963628 scopus 로고    scopus 로고
    • Regulation of ion transport by protein-protein interaction domains
    • O. Staub, and D. Rotin Regulation of ion transport by protein-protein interaction domains Curr Opin Nephrol Hypertens 6 1997 447 454
    • (1997) Curr Opin Nephrol Hypertens , vol.6 , pp. 447-454
    • Staub, O.1    Rotin, D.2
  • 272
    • 0032475976 scopus 로고    scopus 로고
    • Identification of sorting determinants in the C-terminal cytoplasmic tails of the gamma-aminobutyric acid transporters GAT-2 and GAT-3
    • T.R. Muth, J. Ahn, and M.J. Caplan Identification of sorting determinants in the C-terminal cytoplasmic tails of the gamma-aminobutyric acid transporters GAT-2 and GAT-3 J Biol Chem 273 1998 25616 25627
    • (1998) J Biol Chem , vol.273 , pp. 25616-25627
    • Muth, T.R.1    Ahn, J.2    Caplan, M.J.3
  • 273
    • 0034237258 scopus 로고    scopus 로고
    • PDZ domains in synapse assembly and signalling
    • C.C. Garner, J. Nash, and R.L. Huganir PDZ domains in synapse assembly and signalling Trends Cell Biol 10 2000 274 280
    • (2000) Trends Cell Biol , vol.10 , pp. 274-280
    • Garner, C.C.1    Nash, J.2    Huganir, R.L.3
  • 274
    • 0033807807 scopus 로고    scopus 로고
    • Transport rates of GABA transporters: Regulation by the N-terminal domain and syntaxin 1A
    • S.L. Deken, M.L. Beckman, L. Boos, and M.W. Quick Transport rates of GABA transporters: regulation by the N-terminal domain and syntaxin 1A Nat Neurosci 3 2000 998 1003
    • (2000) Nat Neurosci , vol.3 , pp. 998-1003
    • Deken, S.L.1    Beckman, M.L.2    Boos, L.3    Quick, M.W.4
  • 275
    • 16544374349 scopus 로고    scopus 로고
    • Dopamine transporter network and pathways
    • R. Maiya, and R.D. Mayfield Dopamine transporter network and pathways Int Rev Neurobiol 61 2004 79 96
    • (2004) Int Rev Neurobiol , vol.61 , pp. 79-96
    • Maiya, R.1    Mayfield, R.D.2
  • 276
    • 20744445214 scopus 로고    scopus 로고
    • Proteomic analysis of human norepinephrine transporter complexes reveals associations with protein phosphatase 2A anchoring subunit and 14-3-3 proteins
    • U. Sung, J.L. Jennings, A.J. Link, and R.D. Blakely Proteomic analysis of human norepinephrine transporter complexes reveals associations with protein phosphatase 2A anchoring subunit and 14-3-3 proteins Biochem Biophys Res Commun 333 2005 671 678
    • (2005) Biochem Biophys Res Commun , vol.333 , pp. 671-678
    • Sung, U.1    Jennings, J.L.2    Link, A.J.3    Blakely, R.D.4
  • 277
    • 3142781225 scopus 로고    scopus 로고
    • Small-molecule inhibitors of protein-protein interactions: Progressing towards the dream
    • M.R. Arkin, and J.A. Wells Small-molecule inhibitors of protein-protein interactions: progressing towards the dream Nat Rev Drug Discov 3 2004 301 317
    • (2004) Nat Rev Drug Discov , vol.3 , pp. 301-317
    • Arkin, M.R.1    Wells, J.A.2
  • 278
    • 10444276589 scopus 로고    scopus 로고
    • Making protein interactions druggable: Targeting PDZ domains
    • K.K. Dev Making protein interactions druggable: targeting PDZ domains Nat Rev Drug Discov 3 2004 1047 1056
    • (2004) Nat Rev Drug Discov , vol.3 , pp. 1047-1056
    • Dev, K.K.1
  • 279
    • 20744456475 scopus 로고    scopus 로고
    • Correlation between gene expression profiles and protein-protein interactions within and across genomes
    • N. Bhardwaj, and H. Lu Correlation between gene expression profiles and protein-protein interactions within and across genomes Bioinformatics 21 2005 2730 2738
    • (2005) Bioinformatics , vol.21 , pp. 2730-2738
    • Bhardwaj, N.1    Lu, H.2
  • 280
    • 22244447463 scopus 로고    scopus 로고
    • Assessing the limits of genomic data integration for predicting protein networks
    • L.J. Lu, Y. Xia, A. Paccanaro, H. Yu, and M. Gerstein Assessing the limits of genomic data integration for predicting protein networks Genome Res 15 2005 945 953
    • (2005) Genome Res , vol.15 , pp. 945-953
    • Lu, L.J.1    Xia, Y.2    Paccanaro, A.3    Yu, H.4    Gerstein, M.5
  • 281
    • 25144516911 scopus 로고    scopus 로고
    • Consolidating the set of known human protein-protein interactions in preparation for large-scale mapping of the human interactome
    • A.K. Ramani, R.C. Bunescu, R.J. Mooney, and E.M. Marcotte Consolidating the set of known human protein-protein interactions in preparation for large-scale mapping of the human interactome Genome Biol 6 2005 R40
    • (2005) Genome Biol , vol.6 , pp. 40
    • Ramani, A.K.1    Bunescu, R.C.2    Mooney, R.J.3    Marcotte, E.M.4
  • 282
    • 76749159734 scopus 로고    scopus 로고
    • Dynamin-1 co-associates with native mouse brain BKCa channels: Proteomics analysis of synaptic protein complexes
    • G. Gorini, O. Ponomareva, K.S. Shores, M.D. Person, R.A. Harris, and R.D. Mayfield Dynamin-1 co-associates with native mouse brain BKCa channels: proteomics analysis of synaptic protein complexes FEBS Lett 584 2010 845 851
    • (2010) FEBS Lett , vol.584 , pp. 845-851
    • Gorini, G.1    Ponomareva, O.2    Shores, K.S.3    Person, M.D.4    Harris, R.A.5    Mayfield, R.D.6
  • 283
  • 284
    • 57649137989 scopus 로고    scopus 로고
    • Gene expression profiling in blood: New diagnostics in alcoholism and addiction?
    • R.D. Mayfield, and R.A. Harris Gene expression profiling in blood: new diagnostics in alcoholism and addiction? Neuropsychopharmacology 34 2009 250 251
    • (2009) Neuropsychopharmacology , vol.34 , pp. 250-251
    • Mayfield, R.D.1    Harris, R.A.2
  • 285
    • 0346829862 scopus 로고    scopus 로고
    • Direct measurement of alcohol and its metabolites
    • R. Swift Direct measurement of alcohol and its metabolites Addiction 98 Suppl. 2 2003 73 80
    • (2003) Addiction , vol.98 , Issue.SUPPL. 2 , pp. 73-80
    • Swift, R.1
  • 286
    • 77952931598 scopus 로고    scopus 로고
    • Alcohol biomarkers in applied settings: Recent advances and future research opportunities
    • R.Z. Litten, A.M. Bradley, and H.B. Moss Alcohol biomarkers in applied settings: recent advances and future research opportunities Alcohol Clin Exp Res 34 2010 955 967
    • (2010) Alcohol Clin Exp Res , vol.34 , pp. 955-967
    • Litten, R.Z.1    Bradley, A.M.2    Moss, H.B.3
  • 287
    • 0035497644 scopus 로고    scopus 로고
    • The activity of beta-hexosaminidase (uHex) and gamma-glutamyl-transferase (uGGT) in urine as non-invasive markers of chronic alcohol abuse: I. Alcohol-dependent subjects
    • E. Taracha, B. Habrat, P. Wozniak, J. Walkowiak, and B. Szukalski The activity of beta-hexosaminidase (uHex) and gamma-glutamyl-transferase (uGGT) in urine as non-invasive markers of chronic alcohol abuse: I. Alcohol-dependent subjects World J Biol Psychiatry 2 2001 184 189
    • (2001) World J Biol Psychiatry , vol.2 , pp. 184-189
    • Taracha, E.1    Habrat, B.2    Wozniak, P.3    Walkowiak, J.4    Szukalski, B.5
  • 288
    • 33845400236 scopus 로고    scopus 로고
    • Biomarkers in alcoholism
    • O. Niemela Biomarkers in alcoholism Clin Chim Acta 377 2007 39 49
    • (2007) Clin Chim Acta , vol.377 , pp. 39-49
    • Niemela, O.1
  • 289
    • 26644458338 scopus 로고    scopus 로고
    • Validity of carbohydrate-deficient transferrin (%CDT), gamma-glutamyltransferase (gamma-GT) and mean corpuscular erythrocyte volume (MCV) as biomarkers for chronic alcohol abuse: A study in patients with alcohol dependence and liver disorders of non-alcoholic and alcoholic origin
    • B. Hock, M. Schwarz, I. Domke, V.P. Grunert, M. Wuertemberger, and U. Schiemann Validity of carbohydrate-deficient transferrin (%CDT), gamma-glutamyltransferase (gamma-GT) and mean corpuscular erythrocyte volume (MCV) as biomarkers for chronic alcohol abuse: a study in patients with alcohol dependence and liver disorders of non-alcoholic and alcoholic origin Addiction 100 2005 1477 1486
    • (2005) Addiction , vol.100 , pp. 1477-1486
    • Hock, B.1    Schwarz, M.2    Domke, I.3    Grunert, V.P.4    Wuertemberger, M.5    Schiemann, U.6
  • 290
    • 0033828818 scopus 로고    scopus 로고
    • Objective diagnosis of alcohol abuse: Compared values of carbohydrate-deficient transferrin (CDT), gamma-glutamyl transferase (GGT), and mean corpuscular volume (MCV)
    • M. Reynaud, F. Schellenberg, M.N. Loisequx-Meunier, R. Schwan, B. Maradeix, and F. Planche Objective diagnosis of alcohol abuse: compared values of carbohydrate-deficient transferrin (CDT), gamma-glutamyl transferase (GGT), and mean corpuscular volume (MCV) Alcohol Clin Exp Res 24 2000 1414 1419
    • (2000) Alcohol Clin Exp Res , vol.24 , pp. 1414-1419
    • Reynaud, M.1    Schellenberg, F.2    Loisequx-Meunier, M.N.3    Schwan, R.4    Maradeix, B.5    Planche, F.6
  • 291
    • 0035713119 scopus 로고    scopus 로고
    • Carbohydrate-deficient transferrin for detection and monitoring of sustained heavy drinking. What have we learned? Where do we go from here?
    • R.F. Anton Carbohydrate-deficient transferrin for detection and monitoring of sustained heavy drinking. What have we learned? Where do we go from here? Alcohol 25 2001 185 188
    • (2001) Alcohol , vol.25 , pp. 185-188
    • Anton, R.F.1
  • 293
    • 1642388323 scopus 로고    scopus 로고
    • Accuracy of carbohydrate-deficient transferrin in the detection of excessive alcohol consumption: A systematic review
    • H. Koch, G.J. Meerkerk, J.O. Zaat, M.F. Ham, R.J. Scholten, and W.J. Assendelft Accuracy of carbohydrate-deficient transferrin in the detection of excessive alcohol consumption: a systematic review Alcohol Alcohol 39 2004 75 85
    • (2004) Alcohol Alcohol , vol.39 , pp. 75-85
    • Koch, H.1    Meerkerk, G.J.2    Zaat, J.O.3    Ham, M.F.4    Scholten, R.J.5    Assendelft, W.J.6
  • 294
    • 2942665883 scopus 로고    scopus 로고
    • Laboratory markers carbohydrate-deficient transferrin, gamma-glutamyltransferase, and mean corpuscular volume are not useful as screening tools for high-risk drinking in the general population: Results from the Study of Health in Pomerania (SHIP)
    • D. Alte, J. Luedemann, H.J. Rose, and U. John Laboratory markers carbohydrate-deficient transferrin, gamma-glutamyltransferase, and mean corpuscular volume are not useful as screening tools for high-risk drinking in the general population: results from the Study of Health in Pomerania (SHIP) Alcohol Clin Exp Res 28 2004 931 940
    • (2004) Alcohol Clin Exp Res , vol.28 , pp. 931-940
    • Alte, D.1    Luedemann, J.2    Rose, H.J.3    John, U.4
  • 295
    • 0035995992 scopus 로고    scopus 로고
    • Laboratory tests for acute alcohol consumption: Results of the WHO/ISBRA Study on State and Trait Markers of Alcohol Use and Dependence
    • A. Helander, and C.J. Eriksson Laboratory tests for acute alcohol consumption: results of the WHO/ISBRA Study on State and Trait Markers of Alcohol Use and Dependence Alcohol Clin Exp Res 26 2002 1070 1077
    • (2002) Alcohol Clin Exp Res , vol.26 , pp. 1070-1077
    • Helander, A.1    Eriksson, C.J.2
  • 296
    • 37449004575 scopus 로고    scopus 로고
    • Biomarkers to disclose recent intake of alcohol: Potential of 5-hydroxytryptophol glucuronide testing using new direct UPLC-tandem MS and ELISA methods
    • O. Beck, N. Stephanson, M. Bottcher, N. Dahmen, C. Fehr, and A. Helander Biomarkers to disclose recent intake of alcohol: potential of 5-hydroxytryptophol glucuronide testing using new direct UPLC-tandem MS and ELISA methods Alcohol Alcohol 42 2007 321 325
    • (2007) Alcohol Alcohol , vol.42 , pp. 321-325
    • Beck, O.1    Stephanson, N.2    Bottcher, M.3    Dahmen, N.4    Fehr, C.5    Helander, A.6
  • 299
    • 47149087864 scopus 로고    scopus 로고
    • Ethylglucuronide as a biomarker for ethanol detection
    • J.C. Kissack, J. Bishop, and A.L. Roper Ethylglucuronide as a biomarker for ethanol detection Pharmacotherapy 28 2008 769 781
    • (2008) Pharmacotherapy , vol.28 , pp. 769-781
    • Kissack, J.C.1    Bishop, J.2    Roper, A.L.3
  • 300
    • 39449129609 scopus 로고    scopus 로고
    • Comparison of ethyl glucuronide in hair with phosphatidylethanol in whole blood as post-mortem markers of alcohol abuse
    • P. Bendroth, R. Kronstrand, A. Helander, J. Greby, N. Stephanson, and P. Krantz Comparison of ethyl glucuronide in hair with phosphatidylethanol in whole blood as post-mortem markers of alcohol abuse Forensic Sci Int 176 2008 76 81
    • (2008) Forensic Sci Int , vol.176 , pp. 76-81
    • Bendroth, P.1    Kronstrand, R.2    Helander, A.3    Greby, J.4    Stephanson, N.5    Krantz, P.6
  • 301
    • 42149100497 scopus 로고    scopus 로고
    • Measurement of direct ethanol metabolites in a case of a former driving under the influence (DUI) of alcohol offender, now claiming abstinence
    • F.M. Wurst, M. Yegles, C. Alling, S. Aradottir, J. Dierkes, and G.A. Wiesbeck Measurement of direct ethanol metabolites in a case of a former driving under the influence (DUI) of alcohol offender, now claiming abstinence Int J Legal Med 122 2008 235 239
    • (2008) Int J Legal Med , vol.122 , pp. 235-239
    • Wurst, F.M.1    Yegles, M.2    Alling, C.3    Aradottir, S.4    Dierkes, J.5    Wiesbeck, G.A.6
  • 302
    • 42049121446 scopus 로고    scopus 로고
    • Determination of fatty acid ethyl esters (FAEE) and ethyl glucuronide (EtG) in hair: A promising way for retrospective detection of alcohol abuse during pregnancy?
    • F. Pragst, and M. Yegles Determination of fatty acid ethyl esters (FAEE) and ethyl glucuronide (EtG) in hair: a promising way for retrospective detection of alcohol abuse during pregnancy? Ther Drug Monit 30 2008 255 263
    • (2008) Ther Drug Monit , vol.30 , pp. 255-263
    • Pragst, F.1    Yegles, M.2
  • 303
    • 41349105693 scopus 로고    scopus 로고
    • Measurement of direct ethanol metabolites suggests higher rate of alcohol use among pregnant women than found with the AUDITa pilot study in a population-based sample of Swedish women
    • F.M. Wurst, E. Kelso, W. Weinmann, F. Pragst, M. Yegles, and I. Sundstrom Poromaa Measurement of direct ethanol metabolites suggests higher rate of alcohol use among pregnant women than found with the AUDITa pilot study in a population-based sample of Swedish women Am J Obstet Gynecol 198 2008 407 e1-e5
    • (2008) Am J Obstet Gynecol , vol.198 , pp. 407
    • Wurst, F.M.1    Kelso, E.2    Weinmann, W.3    Pragst, F.4    Yegles, M.5    Sundstrom Poromaa, I.6
  • 305
    • 77952923654 scopus 로고    scopus 로고
    • Editorial commentary: Alcohol biomarker papers
    • R.F. Anton Editorial commentary: alcohol biomarker papers Alcohol Clin Exp Res 34 2010 939 940
    • (2010) Alcohol Clin Exp Res , vol.34 , pp. 939-940
    • Anton, R.F.1
  • 307
    • 4444380045 scopus 로고    scopus 로고
    • Biochemical alcohol screening in primary health care
    • P.M. Miller, and R.F. Anton Biochemical alcohol screening in primary health care Addict Behav 29 2004 1427 1437
    • (2004) Addict Behav , vol.29 , pp. 1427-1437
    • Miller, P.M.1    Anton, R.F.2
  • 308
    • 33646180812 scopus 로고    scopus 로고
    • Apo-AII is an elevated biomarker of chronic non-human primate ethanol self-administration
    • W.M. Freeman, R.S. Gooch, M.E. Lull, T.J. Worst, S.J. Walker, and A.S. Xu Apo-AII is an elevated biomarker of chronic non-human primate ethanol self-administration Alcohol Alcohol 41 2006 300 305
    • (2006) Alcohol Alcohol , vol.41 , pp. 300-305
    • Freeman, W.M.1    Gooch, R.S.2    Lull, M.E.3    Worst, T.J.4    Walker, S.J.5    Xu, A.S.6
  • 309
    • 77955645502 scopus 로고    scopus 로고
    • Pharmacotherapy of alcohol dependence: Past, present and future research
    • L. Leggio, and G. Addolorato Pharmacotherapy of alcohol dependence: past, present and future research Curr Pharm Des 16 2010 2074 2075
    • (2010) Curr Pharm des , vol.16 , pp. 2074-2075
    • Leggio, L.1    Addolorato, G.2
  • 310
    • 33746870694 scopus 로고    scopus 로고
    • The neurobiology of addiction: A neuroadaptational view relevant for diagnosis
    • G.F. Koob The neurobiology of addiction: a neuroadaptational view relevant for diagnosis Addiction 101 Suppl. 1 2006 23 30
    • (2006) Addiction , vol.101 , Issue.SUPPL. 1 , pp. 23-30
    • Koob, G.F.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.