Direct measurement of alcohol and its metabolites

Addiction

Volumn 98, Issue SUPPL. 2, 2003, Pages 73-80

  Swift, Robert ^a,b  

^a BROWN UNIVERSITY   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Ethanol; Measurement; Metabolites; Pharmacokinetics

Indexed keywords

ACETALDEHYDE; ACETIC ACID; ALCOHOL; FATTY ACID ESTER;

ALCOHOL METABOLISM; BLOOD LEVEL; BODY FLUID; DRUG DISTRIBUTION; ELECTROCHEMISTRY; GAS CHROMATOGRAPHY; HUMAN; INFRARED SPECTROSCOPY; MEASUREMENT; METABOLITE; REVIEW; SALIVA LEVEL; URINE LEVEL;

ALCOHOL DRINKING; BIOLOGICAL MARKERS; BREATH TESTS; ETHANOL; HUMANS;

EID: 0346829862     PISSN: 09652140     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1359-6357.2003.00605.x     Document Type: Review

References (34)

1. Bearer, C. F., Lee, S., Salvator, A. E., Minnes, S., Swick, A., Yamashita, T. & Singer, L. T. (1999) Ethyl linoleate in meconium: a biomarker for pre-natal ethanol exposure. Alcoholism: Clinical and Experimental Research, 23, 487-493.
2. Dubowski, K. (1976) Recent developments in breath alcohol analysis. In: Israelstam, S. & Lambert, S., eds. Proceedings of the 6th International Conference on Alcohol Drugs and Traffic Safety, pp. Toronto, Canada: ARF of Toronto.
3. Fujimiya, T., Li, Y. U. & Ohbora, Y. (2000) Michaelis-Menten elimination kinetics of acetate during ethanol oxidation. Alcoholism: Clinical and Experimental Research, 24, 16S-20S.
4. Haber, P. S. (2000) Metabolism of alcohol by the human stomach. Alcoholism: Clinical and Experimental Research, 24 (4), 407-408.
5. Hazelett, S. E., Liebelt, R. A., Brown, W. J., Androulakakis, V., Jarjoura, D. & Truitt, E. B. Jr (1998) Evaluation of acetaldehyde-modified hemoglobin and other markers of chronic heavy alcohol use: effects of gender and hemoglobin concentration. Alcoholism: Clinical and Experimental Research, 22, 1813-1819.
6. Hazelett, S. E., Liebelt, R. A. & Truitt, E. B. Jr (1993) Improved separation of acetaldehyde-induced hemoglobin, Alcoholism: Clinical and Experimental Research, 17, 1107-1111.
7. Jones, A. W. (2000) Aspects of in-vivo pharmacokinetics of alcohol. Alcoholism: Clinical and Experimental Research, 24, 400-403.
8. Jones, A. W. & Anderson, L. (1996) Varability of blood/breath alcohol ratio in drinking drivers. Journal of Forensic Sciences, 41, 916-921.
9. Jones, A. W., Jonsson, K.-A. & Kechagias, S. (1997) Effect of high-fat, high-protein, and high-carbohydrate meals on the pharmacokinetics of a small dose of alcohol. British Journal of Clinical Pharmacology, 44, 521-526.
10. Klein, J., Karaskov, T. & Koren, G. (1999) Fatty acid ethyl esters: a novel biologic marker for heavy in utero ethanol exposure: a case report. Therapeutic Drug Monitoring, 21, 644-646.
11. Kwo, P. Y., Ramchandani, V. A., O'Connor, S., Amann, D., Carr, L. G., Sandrasegaran, K., Kopecky, K. K. & Li, T. K. (1998) Gender differences in alcohol metabolism: Relationship to liver volume and effect of adjusting for body mass. Gastroenterology, 115(6), 1552-1557.
12. Kyle, U. G., Genton, L., Slosman, D. O. & Pichard, C. (2001) Fat-free and fat mass percentiles in 5225 healthy subjects aged 15-98 years. Nutrition, 17, 2001.
13. Lands, E. M. (1998) A review of alcohol clearance in humans. Alcohol, 25, 147-160.
14. Laposata, M. (1998) Fatty acid ethyl esters: ethanol metabolites which mediate ethanol-induced organ damage and serve as markers of ethanol intake. Progress in Lipid Research, 37, 307-316.
15. Levitt, M. D. & Levitt, D. G. (1994) The critical role of the rate of ethanol absorption In the interpretation of studies purporting to demonstrate gastric metabolism of ethanol Journal of Pharmacology and Experimental Therapeutics, 269, 297-304.
16. Levitt, M. D., Li, R., Demaster, E. G., Elson, M., Furne, J. & Levitt, D. G. (1997) Use of measurements of ethanol absorption from stomach and intestine to assess human ethanol metabolism. American Journal of Physiology and Gastrointestinal Liver Physiology, 273, G951-G957.
17. Lieber, C. S. (2000) Ethnic and gender differences in ethanol metabolism. Alcoholism: Clinical and Experimental Research, 24, 417-418.
18. Lin, R. C., S. Shahidi, T. J. Kelly, C. Lumeng & L. Lumeng (1993) Measurement of hemoglobin-acetaldehyde adduct in alcoholic patients. Alcoholism: Clinical and Experimental Research, 17, 669-674.
19. Niemelä, O. (1993) Acetaldehyde adducts of proteins: diagnostic and pathogenic implications in diseases caused by excessive alcohol consumption. Scandinavian Journal of Clinical Laboratory Investigation, 53, 45-54.
20. Payne-James, J. J., Keys, D. W. & Jerreat, P. G. (1995) Salivary alcohol measurement: use in clinical forensic medical practice. Journal of Clinical Forensic Medicine, 2, 41-44.
21. Phillips, M., Greenberg, J. & Andrzejewski, J. (1995) Evaluation of the Alcopatch, a transdermal dosimeter for monitoring alcohol consumption. Alcoholism: Clinical and Experimental Research, 19, 1547-1549.
22. Pragst, F., Auwaerter, V., Sporkert, F. & Spiegel, K. (2001) Analysis of fatty acid ethyl esters in hair as possible markers of chronically elevated alcohol consumption by headspace solid-phase microextraction and gas chromatography-mass spectrometry. Forensic Science International, 121, 76-88.
23. Pronko, P. S., Velichko, M. G., Moroz, A. R. & Rubanovich, N. N. (1997) Low molecular-weight metabolites relevant to ethanol metabolism: Correlation with alcohol withdrawal severity and utility for Identification of alcoholics. Alcohol and Alcoholism, 32, 761-768.
24. Refaai, M. A., Nguyen, P. N., Steffensen, T. S., Evans, R. J., Cluette-Brown, J. E. & Laposata, M. (2002) Liver and adipose tissue fatty acid ethyl esters obtained at autopsy are postmortem markers for premortem ethanol intake. Clinical Chemistry, 48, 77-83.
25. Roine, R. P., Gentry, R. T., Lim, R. T. Jr, Heikkonen, E., Salaspuro, M. & Lieber, C. S. (1993) Comparison of blood alcohol concentrations after beer and whisky. Alcoholism: Clinical and Experimental Research, 17, 709-711.
26. Roizen, M. F., Lichtor, L. & Lane, B. (1990) A 'band-aid' to detect alcohol levels in blood. Anesthesiology, 73, A510.
27. Rosman, A. S., Waraich, A., Baraona, E. & Leiber, C. S. (2000) Disulfiram treatment increases plasma and red blood cell acetaldehyde in abstinent alcoholics. Alcoholism: Clinical and Experimental Research, 24, 958-964.
28. Sarkola, T., Iles, M. R., Kohlenberg-Mueller, K. & Eriksson, C. J. P. (2002) Ethanol, acetaldehyde, acetate, and lactate levels after alcohol intake in white men and women: effect of 4-methylpyrazole. Alcoholism: Clinical and Experimental Research, 26, 239-245.
29. Sillanaukee, P., Seppa, K., Koivula, T., Israel, Y. & Niemala, O. (1992) Acetaldehyde-modified hemoglobin as a marker of alcohol consumption: comparison of two new methods. Journal of Laboratory and Clinical Medicine, 120, 42-47.
30. Swift, R. M. (2000) Transdermal alcohol measurement for estimation of blood alcohol concentration. Alcoholism: Clinical and Experimental Research, 24, 422-423.
31. Swift, R. M., Martin, C., Swette, L., LaConti, A. & Kackley, N. (1992) Studies on a wearable, electronic, transdermal alcohol sensor. Alcoholism: Clinical and Experimental Research, 16, 721-725.
32. Swift, R. M., Santa Ines, M., Almeida, A. & Davidson, D. (1999) A comparison of transdermal alcohol detection and self-report in the determination of alcohol consumption. Alcoholism: Clinical and Experimental Research, 23, 741A.
33. Takeshita, T. & Morimoto, K. (2000) Accumulation of HAA with habitual alcohol drinking in the atypical ALDH2 genotype. Alcoholism: Clinical and Experimental Research, 24, 1-7.
34. Watson, P. E. (1989) Total body water and blood alcohol levels: Updating the fundamentals. In: Crow, K. E. & Batt, R. D., eds. Human Metabolism of Alcohol, vol. 1, pp. 41-56. Boca Raton, FL: CRC Press.