Microarray Analysis of Mouse Brain Gene Expression Following Acute Ethanol Treatment

Neurochemical Research

Volumn 29, Issue 2, 2004, Pages 357-369

  Treadwell, Julie A ^a   Singh, Shiva M ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

Brain; Ethanol; Gene expression; Microarray; Mouse

Indexed keywords

ALCOHOL;

ALCOHOL CONSUMPTION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN; CONTROLLED STUDY; DNA MICROARRAY; FEMALE; GENE CONTROL; GENE EXPRESSION; GENE FUNCTION; GENE IDENTIFICATION; HOMEOSTASIS; MALE; MOUSE; MOUSE STRAIN; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STRESS; UNINDEXED SEQUENCE;

ANIMALS; BRAIN; CENTRAL NERVOUS SYSTEM DEPRESSANTS; COMPUTER SYSTEMS; ETHANOL; FEMALE; GENE EXPRESSION; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SPECIES SPECIFICITY;

ANIMALIA; MURINAE;

EID: 1242269209     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:NERE.0000013738.06437.a6     Document Type: Article

References (73)

1. Crabbe, J. C., Phillips, T. J., Buck, K. J., Cunningham, C. L., and Belknap, J. K. 1999. Identifying genes for alcohol and drug sensitivity: Recent progress and future directions. Trends Neurosci. 22:173-179.
2. Li, T. K. 2000. Pharmacogenetics of responses to alcohol and genes that influence alcohol drinking. J. Stud. Alcohol 61:5-12.
3. Buck, K. J. and Finn, D. A. 2001. Genetic factors in addiction: QTL mapping and candidate gene studies implicate GABAergic genes in alcohol and barbiturate withdrawal in mice. Addiction 96:139-149.
4. Prescott, C. A. and Kendler, K. S. 1999. Genetics and environmental contributions to alcohol abuse and dependence in a population-based sample of male twins. Am. J. Psychiatry 156:34-40.
5. Schuckit, M. A. 1994. A clinical model of genetic influences in alcohol dependence. J. Stud. Alcohol 55:5-17.
6. Fan, L., van der Brug, M., Chen, W.-B., Dodd, P. R., Matsumoto, I., Niwa, S., and Wilce, P. A. 1999. Increased expression of a mitochondrial gene in human alcoholic brain revealed by differential display. Alcohol. Clin. Exp. Res. 23:408-415.
7. Lewohl, J. M., Wang, L., Miles, M. F., Zhang, L., Dodd, P. R., and Harris, R. A. 2000. Gene expression in human alcoholism: Microarray analysis of frontal cortex. Alcohol. Clin. Exp. Res. 24:1873-1882.
8. Mayfield, R. D., Lewohl, J. M., Dodd, P. R., Herlihy, A., Liu, J., and Harris, R. A. 2002. Patterns of gene expression are altered in the frontal and motor cortices of human alcoholics. J. Neurochem. 81:802-813.
9. Thibault, C., Lai, C., Wilke, N., Duong, B., Olive, M. F., Rahman, S., Dong, H., Hodge, C. W., Lockhart, D. J., and Miles, M. F. 2000. Expression profiling of neural cells reveals specific patterns of ethanol-responsive gene expression. Mol. Pharmacol. 52:1593-1600.
10. Rimondini, R., Arlinde, C., Sommer, W., and Heilig, M. 2002. Long-lasting increase in voluntary ethanol consumption and transcriptional regulation in the rat brain after intermittent exposure to alcohol. FASEB J. 16:27-35.
11. Saito, M., Smiley, J., Toth, R., and Vadasz, C. 2002. Microarray analysis of gene expression in rat hippocampus after chronic ethanol treatment. Neurochem. Res. 27:1221-1229.
12. Schuckit, M. A. and Smith, T. L. 1996. An 8-year follow-up of 450 sons of alcoholic and control subjects. Arch. Gen. Psychiatry 53:202-210.
13. Crawley, J. N., Belknap, J. K., Collins, A., Crabbe, J. C., Frankel, W., Henderson, N., Hitzemann, R. J., Maxson, S. C., Miner, L. L., Silva, A. J., Wehner, J. M., Wynshaw-Boris, A., and Paylor, R. 1997. Behavioral phenotypes of inbred mouse strains: Implications and recommendations for molecular studies. Psychopharmacology (Berl.) 132:107-124.
14. Chomczynski, P. and Sacchi, N. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:156-159.
15. Li, Y. and Sarkar, F. 2002. Down-regulation of invasion and angiogenesis-related genes identified by cDNA microarray analysis of PC3 prostate cancer cells treated with genistein. Cancer Lett. 186:157-165.
16. Welling, D. B., Lasak, J. M., Akhmametyeva, E., Ghaheri, B., and Chang, L. S. 2002. cDNA microarray analysis of vestibular schwannomas. Otol. Neurotol. 23:736-748.
17. Rahman, S. and Miles, M. F. 2001. Identification of novel ethanol-sensitive genes by expression profiling. Pharmacol. Ther. 92:123-134.
18. Wurmbach, E., Gonzalez-Maeso, J., Yuen, T., Ebersole, B. J., Mastaitis, J. W., Mobbs, C. V., and Sealfon, S. C. 2002. Validated genomic approach to study differentially expressed genes in complex tissues. Neurochem. Res. 27:1027-1033.
19. Daniels, G. M. and Buck, K. J. 2002. Expression profiling identifies strain-specific changes associated with ethanol withdrawal in mice. Genes Brain Behav. 1:35-45.
20. Bakay, M., Chen, Y.-W., Borup, R., Zhao, P., Nagaraju, K., and Hoffman, E. P. 2002. Sources of variability and effect of experimental approach on expression profiling data interpretation. BMC Bioinformatics 3:4.
21. Yuen, T., Wurmbach, E., Pfeffer, R. L., Ebersole, B. J., and Sealfon, S. C. 2002. Accuracy and calibration of commercial oligonucleotide and custom cDNA microarrays. Nucleic Acids Res. 30:e48.
22. Lu, S. C., Alvarez, L., Huang, Z.-Z., Chen, L., An, W., Corrales, F. J., Avila, M. A., Kanel, G., and Mato, J. M. 2001. Methionine adenosyltransferase 1A knockout mice are predisposed to liver injury and exhibit increased expression of genes involved in proliferation. Proc. Natl. Acad. Sci. USA 98:5560-5565.
23. Zhao, X., Lein, E. S., He, A., Smith, S. C., Aston, C., and Gage, F. H. 2001. Transcriptional profiling reveals strict boundaries between hippocampal subregions. J. Comp. Neurol. 441:187-196.
24. Matejuk, A., Dwyer, J., Zamora, A., Vandenbark, A. A., and Offner, H. 2002. Evaluation of the effects of 17β-estradiol (17β-E2) on gene expression in experimental autoimmune encephalomyelitis using DNA microarray. Endocrinology 143:313-319.
25. Sokolov, B. P., Polesskaya, O. O., and Uhl, G. R. 2003. Mouse brain gene expression changes after acute and chronic amphetamine. J. Neurochem. 84:244-252.
26. Xu, Y., Ehringer, M., Yang, F., and Sikela, J. M. 2001. Comparison of global brain gene expression profiles between inbred long-sleep and inbred short-sleep mice by high-density gene array hybridization. Alcohol. Clin. Exp. Res. 25:810-818.
27. Asher, O., Cunningham, T. D., Yao, L., Gordon, A. S., and Diamond, I. 2002. Ethanol stimulates cAMP responsive element-mediated transcription via CREB and cAMP-dependent protein kinase. J. Pharmacol. Exp. Ther. 301:66-70.
28. Harrison, M. and Singh, S. M. 2002. Genetics and differential expression of NADH:ubiquinone oxidoreductase B8 subunit in brains of genetic strains of mice differing in voluntary alcohol consumption (VAC). Biochim. Biophys. Acta 1579:164-172.
29. Murphy, B. C., Chiu, T., Harrison, M., Uddin, R. K., and Singh, S. M. 2002. Examination of ethanol responsive liver and brain specific gene expression, in the mouse strains with variable ethanol preferences, using cDNA expression arrays. Biochem. Genet. 40:395-410.
30. Loney, K., Uddin, K. R., and Singh, S. M. 2003. Strain-specific brain metallothionein (MT-II) gene expression, its ethanol responsiveness, and association with voluntary alcohol consumption (VAC) in mice. Alcohol. Clin. Exp. Res. 27:388-395.
31. Luo, J. and Miller, M. W. 2000. Ethanol enhances erbB-mediated migration of human breast cancer cess in culture. Breast Cancer Res. Treat. 63:61-69.
32. Tomasini, R., Samir, A. A., Vaccaro, M. I., Pebusque, M.-J., Dagorn, J. C., Iovanna, J. L., and Dusetti, N. J. 2001. Molecular and functional characterization of the stress-induced protein (SIP) gene and its two transcripts generated by alternative splicing. J. Biol. Chem. 276:44185-44192.
33. Singh, L. D., Singh, S. P., Handa, R. K., Ehmann, S., and Snyder, A. K. 1996. Effects of ethanol on GLUTI protein and gene expression in rat astrocytes. Metab. Brain Dis. 11:343-357.
34. Montoliu, C., Sanchotello, M., Azorin, I., Burgal, M., Valles, S., Renaupiqueras, J., and Guerri, C. 1995. Ethanol increases cytochrome P450-2E1 and induces oxidative stress in astrocytes. J. Neurochem. 65:2561-2570.
35. Guo, W., Baluda, M. A., and Park, N. H. 1997. Ethanol upregulates the expression of p21 WAF1/CIP1 and prolongs G1 transition via a p53-independent pathway in human epithelial cells. Oncogene 15:1143-1149.
36. Kitamura, Y., Ota, T., Matsuoka, Y., Tooyama, I., Kimura, H., Shimohama, S., Nomura, Y., Gebicke-Haerter, P. J., and Taniguchi, T. 1999. Hydrogen peroxide-induced apoptosis mediated by p53 protein in glial cells. Glia 25:154-164.
37. 2-M checkpoint in response to oxidative stress. J. Biol. Chem. 277:26729-26732.
38. Velasco-Miguel, S., Buckbinder, L., Jean, P., Gelbert, L., Talbott, R., Laidlaw, J., Seizinger, B., and Kley, N. 1999. PA26, a novel target of the p53 tumor suppressor and member of the GADD family of DNA damage and growth arrest inducible genes. Oncogene 18:127-137.
39. Yoshida, Y., Matsuda, S., Ikematsu, N., Kawamura-Tsuzuku, J., Inazawa, J., Umemori, H., and Yamamoto, T. 1998. ANA, a novel member of Tob/BTG1 family, is expressed in the ventricular zone of the developing central nervous system. Oncogene 16:2687-2693.
40. 3 up-regulated protein I mediates oxidative stress via suppressing the thioredoxin function. J. Immunol. 164:6287-6295.
41. Tomasini, R., Samir, A. A., Pebusque, M.-J., Calvo, E. L., Totaro, S., Dagorn, J. C., Dusetti, N. J., and Iovanna, J. L. 2002. p53-Dependent expression of the stress-induced protein (SIP). Eur. J. Cell Biol. 81:294-301.
42. Brouard, S., Berberat, P. O., Tobiasch, E., Seldon, M. P., Bach, F. H., and Soares, M. P. 2002. Heme oxygenase-1-derived carbon monoxide requires the activation of transcription factor NF-kappa B to protect endothelial cells from tumor necrosis factor-alpha-mediated apoptosis. J. Biol. Chem. 277:17950-17961.
43. Xu, L., Zhan, Y., Wang, Y., Feuerstein, G. Z., and Wang, X. 2002. Recombinant adenoviral expression of dominant negative IκBα protects the brain from cerebral ischemic injury. Biochem. Biophys. Res. Comm. 299:14-17.
44. Zhou, Z., Sun, X., and Kang, Y. J. 2002. Metallothionein protection against alcoholic liver injury through inhibition of oxidative stress. Exp. Biol. Med. (Maywood) 227:214-222.
45. Hidalgo, J., Aschner, M., Zatta, P., and Vasak, M. 2001. Roles of the metallothionein family of proteins in the central nervous system. Brain Res. Bull. 55:133-145.
46. Imaizumi, K., Tsuda, M., Wanaka, A., Tohyama, M., and Takagi, T. 1994. Differential expression of sgk mRNA, a member of the Ser/Thr protein kinase gene family, in rat brain after CNS injury. Brain Res. Mol. Brain Res. 26:189-196.
47. Liu, D., Yang, X., and Songyang, Z. 2000. Identification of CISK, a new member of the SGK kinase family that promotes IL-3-dependent survival. Curr. Biol. 10:1233-1236.
48. Mikosz, C. A., Brickley, D. R., Sharkey, M. S., Moran, T. W., and Conzen, S. D. 2001. Glucocorticoid receptor-mediated protection from apoptosis is associated with induction of the serine/threonine survival kinase gene, sgk-1. J. Biol. Chem. 276:16649-16654.
49. Shoshani, T., Faerman, A., Mett, I., Zelin, E., Tenne, T., Gorodin, S., Moshel, Y., Elbaz, S., Budanov, A., Chaju, A., Kalinski, H., Kamer, I., Rozen, A., Mor, O., Keshet, E., Leshkowitz, D., Einat, P., Skaliter, R., and Feinstein, E. 2002. Identification of a novel hypoxia-inducible factor 1-responsive gene, RTP801, involved in apoptosis. Mol. Cell Biol. 22:2283-2293.
50. Nichols, C. D. and Sanders-Bush, E. 2002. A single dose of lysergic acid diethylamide influences gene expression patterns within the mammalian brain. Neuropsychopharmacology 26:634-642.
51. 2 dopaminergic receptors and it potentiates dopamine-mediated prolactin secretion in lactotrophs in vitro. Life Sci. 63:215-222.
52. Arvanov, V. L., Liang, X., Russo, A., and Wang, R. Y. 1999. LSD and DOB: Interaction with 5-HT2A receptors to inhibit NMDA receptor-mediated transmission in the rat prefrontal cortex. Eur. J. Neurosci. 9:3064-3072.
53. Cannella, B., Pitt, D., Marchionni, M., and Raine, C. S. 1999. Neuregulin and erbB receptor expression in normal and diseased human white matter. J. Neuroimmunol. 100:233-242.
54. Fu, H., Qi, Y., Tan, M., Cai, J., Takebayashi, H., Nakafuku, M., Richardson, W., and Qiu, M. 2002. Dual origin of spinal oligodendrocyte progenitors and evidence for the cooperative role of Olig2 and Nkx2.2 in the control of oligodendrocyte differentiation. Development 129:681-693.
55. Kril, J. J., Halliday, G. M., Svoboda, M. D., and Cartwright, H. 1997. The cerebral cortex is damaged in chronic alcoholics. Neuroscience 79:983-998.
56. Lampl, C. and Yazdi, K. 2002. Central pontine myelinolysis. Eur. Neurol. 47:3-10.
57. Grunwald, F., Schrock, H., Biersack, H. J., and Kuschinsky, W. 1993. Changes in local cerebral glucose utilization in the awake rat during acute and chronic administration of ethanol. J. Nucl. Med. 34:793-798.
58. Williams-Hemby, L., Grant, K. A., Gatto, G. J., and Porrino, L. J. 1996. Metabolic mapping of the effects of chronic voluntary ethanol consumption in rats. Pharmacol. Biochem. Behav. 54:415-423.
59. Smith, D. G., Learn, J. E., McBride, W. J., Lumeng, L., Li, T. K., and Murphy, J. M. 2001. Long-term effects of alcohol drinking on cerebral glucose utilization in alcohol-preferring rats. Pharmacol. Biochem. Behav. 69:543-553.
60. Handa, R. K., DeJoseph, M. R., Singh, L. D., Hawkins, R. A., and Singh, S. P. 2000. Glucose transporters and glucose utilization in rat brain after acute ethanol administration. Metab. Brain Dis. 15:211-222.
61. Tomás, M., Fornas, E., Megías, L., Durán, J.-M., Portolés, M., Guerri, C., Egea, G., and Renau-Piqueras, J. 2002. Ethanol impairs monosaccharide uptake and glycosylation in cultured rat astrocytes. J. Neurochem. 83:601-612.
62. Hu, I. C., Singh, S. P., and Snyder, A. K. 1995. Effects of ethanol on glucose transporter expression in cultured hippocampal neurons. Alcohol. Clin. Exp. Res. 19:1398-1402.
63. Poirier, L. A., Rachdaoui, N., and Nagy, L. E. 2001. GLUT4 vesicle trafficking in rat adipocytes after ethanol feeding: regulation of heterotrimeric G-proteins. Biochem. J. 354:323-330.
64. El Messari, S., Ait-Ikhlef, A., Ambrose, D. H., Penicaud, L., and Arluison, M. 2002. Expression of insulin-responsive glucose transporter GLUT4 mRNA in the rat brain and spinal cord: An in situ hybridization study. J. Chem. Neuroanat. 24:225-242.
65. Gray, S., Feinberg, M. W., Hull, S., Kuo, C. T., Watanabe, M., Sen-Banerjee, S., DePina, A., Haspel, R., and Jain, M. K. 2002. The Kruppel-like factor KLF15 regulates the insulin-sensitive glucose transporter GLUT4. J. Biol. Chem. 277:34322-34328.
66. Rowles, J., Scherer, S. W., Xi, T., Majer, M., Nickle, D. C., Rommens, J. M., Popov, K. M., Harris, R. A., Riebow, N. L., Xia, J., Tsui, L. C., Bogardus, C., and Prochazka, M. 1996. Cloning and characterization of PDK4 on 7q21.3 encoding a fourth pyruvate dehydrogenase kinase isoenzyme in human. J. Biol. Chem. 271:22376-22382.
67. Markel, P., Bennett, B., Beeson, M., Gordon, L., and Johnson, T. 1997. Confirmation of quantitative trait loci for ethanol sensitivity in long-sleep and short-sleep mice. Genome Res. 7:92-99.
68. Buck, K. J., Metten, P., Belknap, J. K., and Crabbe, J. C. 1997. Quantitative trait loci involved in genetic predisposition to acute alcohol withdrawal in mice. J. Neurosci. 17:3946-3955.
69. Tarantino, L. M., McLeam, G. E., Rodriguez, L. A., and Plomin, R. 1998. Confirmation of quantitative trait loci for alcohol preference in mice. Alcohol. Clin. Exp. Res. 22:1099-1105.
70. Belknap, J. K., Crabbe, J. C., and Young, E. R. 1993. Voluntary consumption of ethanol in 15 inbred mouse strains. Psychopharmacology (Berl.) 112:503-510.
71. Belknap, J. K., Metten, P., Helms, M. L., O'Toole, L. A., Angeli-Gade, S., Crabbe, J. C., and Phillips, T. J. 1993. Quantitative trait loci (QTL) applications to substances of abuse: Physical dependence studies with nitrous oxide and ethanol in BXD mice. Behav. Genet. 23:213-222.
72. Browman, D. E. and Crabbe, J. C. 2000. Quantitative trait loci affecting ethanol sensitivity in BXD recombinant inbred mice. Alcohol. Clin. Exp. Res. 24:17-23.
73. Shelton, K. L. and Grant, K. A. 2002. Discriminative stimulus effects of ethanol in C57BL/6J and DBA/2J inbred mice. Alcohol. Clin. Exp. Res. 26:747-757.