Synaptic proteome changes in the superior frontal gyrus and occipital cortex of the alcoholic brain

Proteomics - Clinical Applications

Volumn 3, Issue 6, 2009, Pages 730-742

  Etheridge, Naomi ^a   Lewohl, Joanne M ^b   Mayfield, R Dayne ^c   Harris, R Adron ^c   Dodd, Peter R ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b GRIFFITH UNIVERSITY   (Australia)

^c UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

Human brain; OC; SFG; Synapse

Indexed keywords

ADULT; AGED; ALCOHOLISM; AMINO ACID SEQUENCE; ARTICLE; AUTOPSY; BRAIN CORTEX; BRAIN REGION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FUNCTIONAL PROTEOMICS; HUMAN; HUMAN TISSUE; MALE; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NERVE CELL PLASTICITY; NEUROPATHOLOGY; OCCIPITAL CORTEX; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN METABOLISM; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; SUPERIOR FRONTAL GYRUS; SYNAPTIC POTENTIAL; TISSUE SPECIFICITY; TRANSPORT VESICLE; TWO DIMENSIONAL GEL ELECTROPHORESIS;

EID: 70350087346     PISSN: 18628346     EISSN: None     Source Type: Journal    
DOI: 10.1002/prca.200800202     Document Type: Article

References (59)

1. WHO, World Health Organization, Geneva, Switzerland 2004.
2. Thomas, G. J., Dodd, P. R., Regional-specific alterations in the GABA-benzodiazepine receptors in the brain of human chronic-alcoholism. J. Neurochem. 1993, 61, S76-S76.
3. Harper, C., Matsumoto, I., Ethanol and brain damage. Curr. Opin. Pharm. 2005, 5, 73-78.
4. Harper, C. G., Kril, J. J., Neuropathology of alcoholism. Alcohol Alcohol. 1990, 25, 207-216.
5. Jensen, G. B., Pakkenberg, B., Do alcoholics drink their neurons away. Lancet 1993, 342, 1201-1204.
6. Kril, J. J., Halliday, G. M., Svoboda, M. D., Cartwright, H., The cerebral cortex is damaged in chronic alcoholics. Neuroscience 1997, 79, 983-998.
7. Pfefferbaum, A., Sullivan, E. V., Rosenbloom, M. J., Mathalon, H., Lim, K. O., A controlled study of cortical gray matter and ventricular changes in alcoholic men over a 5-year interval. Arch. Gen. Psychiatry 1998, 55, 905-912.
8. Harper, C., Kril, J., If you drink your brain will shrink - neuropathological considerations. Alcohol Alcohol. 1991, 375-380.
9. Hermann, D., Smolka, M. N., Klein, S., Heinz, A. et al., Reduced fMRI activation of an occipital area in recently detoxified alcohol-dependent patients in a visual and acoustic stimulation paradigm. Addict. Biol. 2007, 12, 117-121.
10. Wang, G. J., Volkow, N. D., Franceschi, D., Fowler, J. S. et al., Regional brain metabolism during alcohol intoxication. Alcohol. Clin. Exp. Res. 2000, 24, 822-829.
11. Zhu, W., Volkow, N. D., Ma, Y., Fowler, J. S., Wang, G. J., Relationship between ethanol-induced changes in brain regional metabolism and its motor, behavioural and cognitive effects. Alcohol Alcohol. 2004, 39, 53-58.
12. Lewohl, J. M., Wang, L., Miles, M. F., Zhang, L. et al., Gene expression in human alcoholism: microarray analysis of frontal cortex. Alcohol. Clin. Exp. Res. 2000, 24, 1873-1882.
13. Mayfield, R. D., Lewohl, J. M., Dodd, P. R., Herlihy, A. et al., Patterns of gene expression are altered in the frontal and motor cortices of human alcoholics. J. Neurochem. 2002, 81, 802-813.
14. Alexander-Kaufman, K., Cordwell, S., Harper, C., Matsumoto, I., A proteome analysis of the dorsolateral prefrontal cortex in human alcoholic patients. Proteomics Clin. Appl. 2007, 1, 62-72.
15. Lewohl, J. M., Van Dyk, D. D., Craft, G. E., Innes, D. J. et al., The application of proteomics to the human alcoholic brain. Ann. N. Y. Acad. Sci. 2004, 1025, 14-26.
16. Dodd, P. R., Hardy, J. A., Oakley, A. E., Edwardson, J. A. et al., A rapid method for preparing synaptosomes - comparison, with alternative procedures. Brain Res. 1981, 226, 107-118.
17. Shevchenko, A., Loboda, A., Ens, W., Schraven, B. et al., Archived polyacrylamide gels as a resource for proteome characterization by mass spectrometry. Electrophoresis 2001, 22, 1194-1203.
18. Fountoulakis, M., Juranville, J. F., Dierssen, M., Lubec, G., Proteomic analysis of the fetal brain. Proteomics 2002, 2, 1547-1576.
19. Langen, H., Berndt, P., Röder, D., Cairns, N. et al., Two-dimensional map of human brain proteins. Electrophoresis 1999, 20, 907-916.
20. Yang, J. W., Juranville, J. F., Höger, H., Fountoulakis, M., Lubec, G., Molecular diversity of rat brain proteins as revealed by proteomic analysis. Mol. Divers. 2005, 9, 385-396.
21. McCarthy, J., Hopwood, F., Oxley, D., Laver, M. et al., Carbamylation of proteins in 2-D electrophoresis - myth or reality? J. Prot. Res. 2003, 2, 239-242.
22. Righetti, P. G., Real and imaginary artefacts in proteome analysis via two-dimensional maps. J. Chromatogr. B 2006, 841, 14-22.
23. Franzen, B., Yang, Y., Sunnemark, D., Wickman, M. et al., Dihydropyrimidinase related protein-2 as a biomarker for temperature and time dependent post mortem changes in the mouse brain proteome. Proteomics 2003, 3, 1920-1929.
24. Alexander-Kaufman, K., James, G., Sheedy, D., Harper, C., Matsumoto, I., Differential protein expression in the prefrontal white matter of human alcoholics: a proteomics study. Mol. Psychiatry 2006, 11, 56-65.
25. Ames, A., CNS energy metabolism as related to function. Brain Res. Rev. 2000, 34, 42-68.
26. Matsuda-Matsumoto, H., Iwazaki, T., Kashem, M. A., Harper, C., Matsumoto, I., Differential protein expression profiles in the hippocampus of human alcoholics. Neurochem. Int. 2007, 51, 370-376.
27. Alexander-Kaufman, K., Harper, C., Wilce, P., Matsumoto, I., Cerebellar vermis proteome of chronic alcoholic individuals. Alcohol. Clin. Exp. Res. 2007, 31, 1286-1296.
28. Kashem, M. A., James, G., Harper, C.,Wilce, P., Matsumoto, I., Differential protein expression in the corpus callosum (splenium) of human alcoholics: a proteomics study. Neurochem. Int. 2007, 50, 450-459.
29. Kashem, M. A., Harper, C., Matsumoto, I., Differential protein expression in the corpus callosum (genu) of human alcoholics. Neurochem. Int. 2008, 53, 1-11.
30. Wang, J., Morris, A. J., Tolan, D. R., Pagliaro, L., This molecular nature of the F-Actin binding-activity of aldolase revealed with site-directed mutants. Mol. Biol. Cell 1995, 6, 812-812.
31. Forlemu, N. Y., Waingeh, V. F., Ouporov, I. V., Lowe, S. L., Thomasson, K. A., Theoretical study of interactions between muscle aldolase and F-actin: insight into different species. Biopolymers 2007, 85, 60-71.
32. Stephan, P., Clarke, F., Morton, D., The indirect binding of triose-phosphate isomerase to myofibrils to form a glycolytic enzyme mini-complex. Biochim. Biophys. Acta 1986, 873, 127-135.
33. Yarar, D., To, W., Abo, A.,Welch, M. D., The Wiskott-Aldrich syndrome protein directs actin-based motility by stimulating actin nucleation with the Arp2/3 complex. Curr. Biol. 1999, 9, 555-558.
34. St-Jean, M., Izard, T., Sygusch, J., A hydrophobic pocket in the active site of glycolytic aldolase mediates interactions with Wiskott-Aldrich syndrome protein. J. Biol. Chem. 2007, 282, 14309-14315.
35. Sultana, R., Boyd-Kimball, D., Cai, J., Pierce, W. M. et al., Proteomics analysis of the Alzheimer's disease hippocampal proteome. J. Alzheimer's Dis. 2007, 11, 153-164.
36. Castegna, A., Aksenov, M., Thongboonkerd, V., Klein, J. B. et al., Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part II: dihydropyrimidinase related protein 2, alpha-enolase and heat shock cognate 71. J. Neurochem. 2002, 82, 1524-1532.
37. Sultana, R., Butterfield, D. A., Redox proteomics studies of in vivo amyloid beta-peptide animal models of Alzheimer's disease: Insight into the role of oxidative stress. Proteomics Clin. Appl. 2008, 2, 685-696.
38. Praefcke, G. J. K., McMahon, H. T., The dynamin super-family: universal membrane tubulation and fission molecules? Nat. Rev. Mol. Cell Biol. 2004, 5, 133-147.
39. Ferguson, S. M., Brasnjo, G., Hayashi, M., Wolfel, M. et al., A selective activity-dependent requirement for dynamin 1 in synaptic vesicle endocytosis. Science 2007, 316, 570-574.
40. Daugaard, M., Rohde, M., Jaattela, M., The heat shock protein 70 family: highly homologous proteins with overlapping and distinct functions. FEBS Lett. 2007, 581, 3702-3710.
41. Calabrese, V., Renis, M., Calderone, A., Russo, A. et al., Stress proteins and SH-groups in oxidant-induced cellular injury after chronic ethanol administration in rat. Free Radical Biol. Med. 1998, 24, 1159-1167.
42. Calabrese, V., Testa, G., Ravagna, A., Bates, T. E., Stella, A. M. G., HSP70 induction in the brain following ethanol administration in the rat: regulation by glutathione redox state. Biochem. Biophys. Res. Commun. 2000, 269, 397-400.
43. Miles, M. F., Diaz, J. E., Deguzman, V. S., Mechanisms of neuronal adaptation to ethanol-ethanol induces Hsc70 gene-transcription in Ng108-15 neuroblastoma × glioma-cells. J. Biol. Chem. 1991, 266, 2409-2414.
44. Damodaran, S., Dlugos, C. A., Wood, T. D., Rabin, R. A., Effects of chronic ethanol administration on brain protein levels: a proteomic investigation using 2-D DIGE system. Eur. J. Pharmacol. 2006, 547, 75-82.
45. Unno, K., Asakura, H., Shibuya, Y., Kaihou, M. et al., Stress response caused by chronic alcohol intake in aged rat brain. Alcohol. Clin. Exp. Res. 2002, 26, 1017-1023.
46. Bonnycastle, L. L. C., Cloning, sequencing, and mapping of the human-chromosome-14 heat-shock protein gene (Hspa2). Genomics 1994, 23, 85-93.
47. Munro, S., Pelham, H. R. B., An HSP70-like protein in the ER - identity with the 78 kd glucose-regulated protein and immunoglobulin heavy-chain binding-protein. Cell 1986, 46, 291-300.
48. Dworniczak, B., Mirault, M. E., Structure and expression of a human-gene coding for a 71 kd heat-shock cognate protein. Nucleic Acids Res. 1987, 15, 5181-5197.
49. Tsukahara, F., Yoshioka, T., Muraki, T., Molecular and functional characterization of HSC54, a novel variant of human heat-shock cognate protein 70. Mol. Pharmacol. 2000, 58, 1257-1263.
50. Mayer, M. P., Bukau, B., Hsp70 chaperones: cellular functions and molecular mechanism. Cell. Mol. Life Sci. 2005, 62, 670-684.
51. Lowenstein, D. H., Chan, P. H., Miles, M. F., The stress protein response in cultured neurons - characterization and evidence for a protective role in excitotoxicity. Neuron 1991, 7, 1053-1060.
52. Chong, K. Y., Lai, C. C., Lille, S., Chang, C. S., Su, C. Y., Stable overexpression of the constitutive form of heat shock protein 70 confers oxidative protection. J. Mol. Cell. Cardiol. 1998, 30, 599-608.
53. Su, C. Y., Chong, K. Y., Edelstein, K., Lille, S. et al., Constitutive HSP70 attenuates hydrogen peroxide-induced membrane lipid peroxidation. Biochem. Biophys. Res. Commun. 1999, 265, 279-284.
54. Das, S. K., Vasudevan, D. M., Alcohol-induced oxidative stress. Life Sci. 2007, 81, 177-187.
55. Sun, A. Y., Sun, G. Y., Ethanol and oxidative mechanisms in the brain. J. Biomed. Sci. 2001, 8, 37-43.
56. Zimatkin, S. M., Pronko, S. P., Vasiliou, V., Gonzalez, F. J., Deitrich, R. A., Enzymatic mechanisms of ethanol oxidation in the brain. Alcohol. Clin. Exp. Res. 2006, 30, 1500-1505.
57. Krystal, J. H., Staley, J., Mason, G., Petrakis, I. L. et al., Gamma-aminobutyric acid type A receptors and alcoholism - intoxication, dependence, vulnerability, and treatment. Arch. Gen. Psychiatry 2006, 63, 957-968.
58. Dodd, P. R., Excited to death: different ways to lose your neurones. Biogerontology 2002, 3, 51-56.
59. Tsai, G. C., Coyle, J. T., The role of glutamatergic neuro-transmission in the pathophysiology of alcoholism. Annu. Rev. Med. 1998, 49, 173-184.