Use of enzymes in the production of semi-synthetic penicillins and cephalosporins: Drawbacks and perspectives

Current Medicinal Chemistry

Volumn 17, Issue 32, 2010, Pages 3855-3873

  Volpato, G ^a   Rodrigues, R C ^b   Fernandez Lafuente, R ^c  

^a Quatro G Pesquisa and Desenvolvimento LTDA   (Brazil)

^b FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^c INSTITUTO DE CATÁLISIS Y PETROLEOQUÍMICA   (Spain)

Author keywords

Antibiotic synthesis; Cephalosporin acylase; D amino acid oxidase; Enzyme reaction design; Glutarayl acylase; Penicillin G acylase

Indexed keywords

AMOXICILLIN; AMPICILLIN; BACAMPICILLIN; CARBENICILLIN; CEFACLOR; CEFADROXIL; CEFALEXIN; CEFALOTIN; CEFAZOLIN; CEFIXIME; CEFMETAZOLE; CEFONICID; CEFOTETAN; CEFRADINE; CEFTIBUTEN; CEFUROXIME; CEPHALOSPORIN C; CLOXACILLIN; DICLOXACILLIN; FLUCLOXACILLIN; INDANYL; METICILLIN; MEZLOCILLIN; NAFCILLIN; OXACILLIN; PENICILLIN G; PENICILLIN V; PIPERACILLIN; TICARCILLIN; UNCLASSIFIED DRUG; UNINDEXED DRUG;

AMIDATION; ARTICLE; BIOCATALYSIS; BIOCATALYST; CATALYSIS; CHEMICAL REACTION; CRYSTALLIZATION; DRUG DECOMPOSITION; DRUG DESIGN; DRUG HYDROLYSIS; DRUG INDUSTRY; DRUG ISOLATION; DRUG MANUFACTURE; DRUG MARKETING; DRUG SCREENING; DRUG SYNTHESIS; DRUG USE; ELECTRODIALYSIS; ENERGY CONSUMPTION; ENZYME ACTIVITY; ENZYME IMMOBILIZATION; ENZYME KINETICS; ENZYME SPECIFICITY; ENZYME SYNTHESIS; METABOLIC ENGINEERING; MICELLIZATION; STRUCTURE ACTIVITY RELATION; THERMODYNAMICS;

ANTI-BACTERIAL AGENTS; CEPHALOSPORINS; D-AMINO-ACID OXIDASE; FERMENTATION; HYDROLYSIS; PENICILLIN AMIDASE; PENICILLIN G; THERMODYNAMICS;

EID: 78650645142     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/092986710793205435     Document Type: Article

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