Evaluation of different enzymes as catalysts for the production of β-lactam antibiotics following a kinetically controlled strategy

Enzyme and Microbial Technology

Volumn 25, Issue 3-5, 1999, Pages 336-343

  Hernandez Justiz O ^a   Terreni, M ^b   Pagani, G ^b   Garcia J L ^c   Guisan J M ^a   Fernandez Lafuente R ^a  

^a CSIC   (Spain)

^b UNIVERSITY OF PAVIA   (Italy)

^c CENTRO DE INVESTIGACIONES BIOLÓGICAS   (Spain)

Author keywords

Ampicillin; Aqueous two phase system; Cephalexin; Cephamandole; Enzymatic synthesis of antibiotics

Indexed keywords

ANTIBIOTICS; BIOCONVERSION; BIOSYNTHESIS; CATALYSTS; ENZYMES; ESTERS; HYDROLYSIS; MICROORGANISMS;

AMPICILLIN; AQUEOUS TWO PHASE SYSTEM; CEPHAMANDOLE; LACTAM ANTIBIOTICS;

ENZYME KINETICS;

AMIDASE; AMPICILLIN; BETA LACTAM ANTIBIOTIC; CEFALEXIN; CEFAMANDOLE; PENICILLIN G;

ACETOBACTER; ARTICLE; BACILLUS MEGATERIUM; CHEMICAL REACTION KINETICS; DRUG MANUFACTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME IMMOBILIZATION; ESCHERICHIA COLI; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; KLUYVEROMYCES; PH; TECHNIQUE;

ACETOBACTER TURBIDANS; BACILLUS MEGATERIUM; ESCHERICHIA COLI; KLUYVERA CITROPHILA;

EID: 0037506386     PISSN: 01410229     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0141-0229(99)00050-2     Document Type: Article

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