Carrier-bound and carrier-free penicillin acylase biocatalysts for the thermodynamically controlled synthesis of β-lactam compounds in organic medium

Enzyme and Microbial Technology

Volumn 43, Issue 6, 2008, Pages 442-447

  Wilson, Lorena ^a   Illanes, Andrés ^a   Romero, Oscar ^a   Vergara, José ^a   Mateo, César ^b  

^a PONTIFICIA UNIVERSIDAD CATÓLICA DE VALPARAÍSO   (Chile)

^b INSTITUTO DE CATÁLISIS Y PETROLEOQUÍMICA   (Spain)

Author keywords

Lactam antibiotics; CLEAs; Organic cosolvents; Penicillin acylase; Thermodynamically controlled synthesis

Indexed keywords

AMINES; ARSENIC COMPOUNDS; BATCH REACTORS; CHLORINE COMPOUNDS; CIVIL AVIATION; DYNAMIC POSITIONING; ENZYMES; ETHERS; FOOD ADDITIVES; PERCOLATION (SOLID STATE); SYSTEM STABILITY;

CLEAS; CO SOLVENTS; CONTROLLED SYNTHESIS; CROSS-LINKED ENZYME AGGREGATES; DIGLYME; ENZYMATIC SYNTHESES; EQUILIBRIUM CONVERSION; GLYOXYL AGAROSE; HALF-LIVES; MICRO ENVIRONMENTS; MODEL REACTION SYSTEM; NO REDUCTION; ORGANIC COSOLVENTS; ORGANIC MEDIUM; PENICILLIN ACYLASE; PHENYL ACETIC ACID; REACTION MEDIUM; SEQUENTIAL BATCH REACTORS; THERMODYNAMICALLY CONTROLLED SYNTHESIS;

COMPLEXATION;

7 AMINO DEACETOXYCEPHALOSPORANIC ACID; AMIDASE; BETA LACTAM ANTIBIOTIC; CARRIER PROTEIN; CEPHALOSPORIN DERIVATIVE; DEACETOXYCEPHALOSPORIN G; DIGLYME; DIOXANE; ORGANIC SOLVENT; PENICILLIN ACYLASE; PHENYLACETIC ACID; SOLVENT; UNCLASSIFIED DRUG;

ARTICLE; BATCH REACTOR; BIOCATALYST; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME BINDING; ENZYME STABILITY; ENZYME SYNTHESIS; NONHUMAN; POLYMERIZATION; THERMODYNAMICS;

EID: 52949085077     PISSN: 01410229     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.enzmictec.2008.07.007     Document Type: Article

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