Two-step, one-pot enzymatic synthesis of cefprozil from -phenylacetamido-3-propenyl-cephalosporanic acid (GPRA)

Biocatalysis and Biotransformation

Volumn 26, Issue 4, 2008, Pages 321-326

  Feng, Sheng Xi ^a   Liang, Shi Zhong ^a   Lou, Wen Yong ^a  

^a SOUTH CHINA UNIVERSITY OF TECHNOLOGY   (China)

Author keywords

7 phenylacetamido 3 propenyl cephalosporanic acid (GPRA); Cefprozil; One pot enzymatic synthesis; Penicillin acylase

Indexed keywords

AMINES; ESCHERICHIA COLI; ESTERS;

CEPHALOSPORANIC ACID; E. COLI; ENZYMATIC SYNTHESES; ENZYMATIC TRANSFORMATIONS; ONE POT; ONE POT SYNTHESIS; PENICILLIN ACYLASE (PAC); PHENYLGLYCINE (PHGH);

ORGANIC COMPOUNDS;

4 HYDROXY PHENYLGLYCINE HYDROXYETHYL ESTER; 7 AMINO 3 PROPENYL CEPHALOSPORANIC ACID; 7 PHENYLACETAMIDO 3 PROPENYL CEPHALOSPORANIC ACID; AMIDASE; CEFPROZIL; CEPHALOSPORANIC ACID DERIVATIVE; ESTER; PENICILLIN ACYLASE;

ACYLATION; ARTICLE; BIOTRANSFORMATION; CATALYSIS; DRUG SYNTHESIS; ENZYME IMMOBILIZATION; ENZYME ISOLATION; ENZYME SPECIFICITY; ENZYME SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROLYSIS; NONHUMAN; ONE POT SYNTHESIS;

EID: 45849114356     PISSN: 10242422     EISSN: 10292446     Source Type: Journal    
DOI: 10.1080/10242420802090925     Document Type: Article

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