Optimization of cephalexin synthesis with immobilized penicillin acylase in ethylene glycol medium at low temperatures

Journal of Molecular Catalysis B: Enzymatic

Volumn 30, Issue 2, 2004, Pages 95-103

  Illanes, A ^a   Anjari M S ^a   Altamirano, C ^a   Aguirre, C ^b  

^a PONTIFICIA UNIVERSIDAD CATÓLICA DE VALPARAÍSO   (Chile)

^b UNIVERSIDAD CATÓLICA DE LA SANTÍSIMA CONCEPCIÓN   (Chile)

Author keywords

Lactam antibiotics; Cephalexin; Enzymatic synthesis; Immobilized enzymes; Penicillin acylase

Indexed keywords

AMINO ACIDS; BIOSYNTHESIS; CARBOXYLIC ACIDS; FUNGI; HIGH TEMPERATURE EFFECTS; ORGANIC SOLVENTS; PH EFFECTS;

ENZYMATIC SYNTHESIS; HYDROLYTIC REACTIONS; WATER ACTIVITY;

ENZYMES;

AMIDASE; CEFALEXIN; ETHYLENE GLYCOL; PENICILLIN ACYLASE; UNCLASSIFIED DRUG;

ARTICLE; BIOCATALYST; CATALYSIS; CONCENTRATION RESPONSE; DRUG SYNTHESIS; ENVIRONMENTAL TEMPERATURE; ENZYME IMMOBILIZATION; PH; STOICHIOMETRY; TEMPERATURE SENSITIVITY;

EID: 2342517327     PISSN: 13811177     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molcatb.2004.01.020     Document Type: Article

References (60)

1. De Vroom E. Chemica Oggi. 17:1999;65
2. Parmar A., Kumar H., Marwaha S., Kennedy J. Crit. Rev. Biotechnol. 18:1998;1
3. Wegman M., Janssen M., van Rantwijk F., Sheldon R. Adv. Synth. Catal. 343:2001;559
4. Adrio J., Cho H., Piret J., Demain A. Enzyme Microb. Technol. 25:1999;496
5. Schroën C., Nierstrasz V., Bosma R., Kroon P., Tjeerdsma P., De Vroom E., van der Laan J., Moody H., Beeftink H., Janssen A., Tramper J. Biotechnol. Bioeng. 80:2002;144
6. Bruggink A., Roos E., de Vroom E. Org. Process Res. Dev. 2:1998;128
7. Yang L., Wei Z. Biotechnol. Lett. 25:2003;1195
8. Shaw S., Shyu J., Hsieh Y., Yeh H. Enzyme Microb. Technol. 26:2000;142
9. Terreni M., Pagani G., Ubiali D., Fernández-Lafuente R., Mateo C., Guisán J. Bioorg. Med. Chem. Lett. 11:2000;2429
10. Kurochkina V., Nys P. Biocatal. Biotransform. 20:2002;35
11. A. Bruggink, Synthesis of β-lactam Antibiotics, Kluwer Academic Publishers, Dordrecht, 2001.
12. Arroyo M., de la Mata I., Acebal C., Castillón M. Appl. Microbiol. Biotechnol. 60:2003;507
13. Fernandez-Lafuente R., Rosell C., Caanan-Haden L., Rodes L., Guisan J. Enzyme Microb. Technol. 24:1999;96
14. Abián O., Mateo C., Fernández-Lorente G., Palomo J., Fernández-Lafuente R., Guisán J. Biocatal. Biotransform. 19:2001;489
15. Cao L., van Langen L.F., van Rantwijk F., Sheldon R. J. Mol. Catal. B: Enzym. 11:2001;665
16. Wilson L., Illanes A., Abián O., Fernández-Lafuente R., Guisán J. Lanbauforschung Völkenrode. 241:2002;121
17. Özturk D., Kazan D., Erarslan E. World J. Microbiol. Biotechnol. 18:2002;881
18. Hari Krishna S. Biotechnol. Adv. 20:2002;239
19. Ó'Fágáin C. Enzyme Microb. Technol. 33:2003;137
20. Ballesteros A., Bornscheuer U., Capewell A., Combes D., Condoret J., Koenig K., Kolisis F., Marty A., Menge U., Scheper T., Stamatis H., Xenakis A. Biocatal. Biotransform. 13:1995;1
21. Klibanov A. Nature. 409:2001;241
22. Hyun C., Kim J., Ryu D. Biotechnol. Bioeng. 42:1993;800
23. Rosell C., Terreni M., Fernández-Lafuente R., Guisán J. Enzyme Microb. Technol. 23:1998;64
24. Arroyo M., Torres-Guzmán R., de la Mata I., Castillón M., Acebal C. Enzyme Microb. Technol. 27:2000;122
25. Arroyo M., Torres-Guzmán R., de la Mata I., Castillón M., Acebal C. Biotechnol. Prog. 16:2000;368
26. Arroyo M., Torres-Guzmán R., de la Mata I., Castillón M., Acebal C. Biocatal. Biotransform. 20:2002;53
27. Illanes A., Fajardo A. J. Mol. Catal. B: Enzym. 11:2001;605
28. Illanes A., Anjarí S., Arrieta R., Aguirre C. Appl. Biochem. Biotechnol. 97:2002;165
29. Fernandez-Lafuente R., Rossell C., Guisán J. Biotechnol. Appl. Biochem. 24:1996;139
30. Schroën C., Nierstrasz V., Kroon P., Bosma R., Janssen A., Beeftink H., Tramper J. Enzyme Microb. Technol. 24:1999;489
31. Nierstrasz V., Schroën C., Bosma R., Kroon P., Beeftink H., Janssen A., Tramper J. Biocatal. Biotransform. 17:1999;209
32. Hernández-Jústiz O., Fernández-Lafuente R., Terreni M., Guisán J. Biotechnol. Bioeng. 59:1999;73
33. Hernández-Jústiz O., Terreni M., Pagani G., García J., Guisán J., Fernández-Lafuente R. Enzyme Microb. Technol. 25:1999;336
34. Schroën C., Nierstrasz V., Moody H., Hoogschagen M., Kroon P., Bosma R., Beeftink H., Janssen A., Tramper J. Biotechnol. Bioeng. 73:2001;171
35. Wei D., Zhu J., Cao X. Biochem. Eng. J. 11:2002;95
36. Schroën C., Mohy Eldin M., Janssen A., Mita G., Tramper J. J. Mol. Catal. B: Enzym. 15:2001;163
37. Diender M., Straathof A., Heijnen J. Biocatal. Biotransform. 16:1998;275
38. Bell G., Halling P., Moore B., Partridge P., Rees D. Trends Biotechnol. 13:1995;468
39. Aguirre C., Toledo M., Medina V., Illanes A. Process Biochem. 38:2002;351
40. Illanes A., Cabrera Z., Wilson L., Aguirre C. Process Biochem. 39:2003;111
41. Shewale J., Kumar K., Ambedkar G. Biotechnol. Tech. 1:1987;69
42. R. Myers, D. Montgomery, Response Surface Methodology: Process and Product Optimization Using Designed Experiments, Wiley, New York, 1995.
43. Kim M., Lee S. J. Mol. Catal. B: Enzym. 1:1996;201
44. Fernández-Lafuente R., Rosell C., Piatkowska B., Guisán J. Enzyme Microb. Technol. 19:1996;9
45. E. Baldaro, Bioorganic chemistry in U. Pandit, F. Alderweireldt (Eds.), Healthcare and Technology, Plenum Press, New York, 1991, p. 237.
46. van Langen L., de Vroom E., van Rantwijk F., Sheldon R. FEBS Lett. 456:1999;89
47. Wei D., Yang L. J. Chem. Technol. Biotechnol. 78:2003;431
48. Schroën C., Fretz C., de Bruin V., Berendsen W., Moody H., Roos E., van Roon J., Kroon P., Strubel A., Janssen A., Tramper J. Biotechnol. Bioeng. 80:2002;331
49. Kasche V. Enzyme Microb. Technol. 8:1986;4
50. C. Aguirre, M. Venegas, A. Illanes, in: Proceedings of the 15th Chilean Congress of Chemical Engineering, Punta Arenas, Chile, 21-25 October 2002, p. 147.
51. Fernández-Lafuente R., Rosell C., Guisán J. Enzyme Microb. Technol. 23:1998;305
52. Trevascio P., Zito E., De Maio A., Schroën C., Durante D., De Luca P., Bencivenga U., Mita D. Biotechnol. Bioeng. 79:2002;334
53. Kasche V. Biotechnol. Lett. 121:1985;877
54. Henley J., Sadana A. Biotechnol. Bioeng. 26:1985;959
55. Henley J., Sadana A. Biotechnol. Bioeng. 28:1986;1277
56. Illanes A., Altamirano C., Zúñiga M. Biotechnol. Bioeng. 50:1996;609
57. Fernández-Lafuente R., Rosell C., Guisán J. Enzyme Microb. Technol. 13:1991;898
58. Khmelnitsky Y., Mozhaev V., Belova A., Sergeeva M., Martinek K. Eur. J. Biochem. 198:1991;31
59. Wegman M., van Langen L., van Rantwijk F., Sheldon R. Biotechnol. Bioeng. 79:2002;356
60. Yang S., Zhou L., Tang H., Pan J., Wu X., Huang H., Yuan Z. J. Mol. Catal. B: Enzym. 18:2002;285