Facile synthesis of artificial enzyme nano-environments via solid-phase chemistry of immobilized derivatives: Dramatic stabilization of penicillin acylase versus organic solvents

Enzyme and Microbial Technology

Volumn 24, Issue 1-2, 1999, Pages 96-103

  Fernandez Lafuente, R ^a   Rosell, C M ^a   Caanan Haden, L ^b   Rodes, L ^b   Guisan, J M ^a  

^a CSIC   (Spain)

^b CENTER FOR GENETIC ENGINEERING AND BIOTECHNOLOGY   (Cuba)

Author keywords

Artificial nano environments; Dextrans; Enzymes in organic media; Immobilized enzymes; Solid phase modification of proteins; Stabilization of enzymes

Indexed keywords

BIOSYNTHESIS; CATALYST ACTIVITY; CATALYST SUPPORTS; CHEMICAL MODIFICATION; COMPOSITION EFFECTS; MACROMOLECULES; MOLECULAR WEIGHT; MORPHOLOGY; NITROGEN COMPOUNDS; ORGANIC POLYMERS; ORGANIC SOLVENTS; POLYSACCHARIDES;

DEXTRAN; HYDROPHILICITY; POLYAMINE;

ENZYME IMMOBILIZATION;

AMIDASE; BORANE DERIVATIVE; ORGANIC SOLVENT; PENICILLIN G;

ARTICLE; CHEMICAL MODIFICATION; CHEMISTRY; DRUG STABILITY; ENZYME IMMOBILIZATION; ENZYME SYNTHESIS; HYDROPHILICITY; MACROMOLECULE; MOLECULAR WEIGHT;

EID: 0032890111     PISSN: 01410229     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0141-0229(98)00102-1     Document Type: Article

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