-
1
-
-
0014642629
-
Penicillins and other acylamino compounds synthesized by the cell-bound penicillin acylase of Escherichia coli
-
Cole M. Penicillins and other acylamino compounds synthesized by the cell-bound penicillin acylase of Escherichia coli. Biochem J 11 (1969) 733-739
-
(1969)
Biochem J
, vol.11
, pp. 733-739
-
-
Cole, M.1
-
2
-
-
0027159506
-
G acylase catalyzed resolution of phenylacetate ester of secondary alcohols
-
Baldaro E., D'Arrigo P., Pedrocchi-Fantoni G., Rosell C.M., Servi S., Tagliani A., et al. G acylase catalyzed resolution of phenylacetate ester of secondary alcohols. Tetrahedron Asimmetry 4 (1993) 1031-1304
-
(1993)
Tetrahedron Asimmetry
, vol.4
, pp. 1031-1304
-
-
Baldaro, E.1
D'Arrigo, P.2
Pedrocchi-Fantoni, G.3
Rosell, C.M.4
Servi, S.5
Tagliani, A.6
-
3
-
-
0032874447
-
Use of enzyme penicillin acylase in selective amidation/amide hydrolysis to resolve ethyl 3-amino-4-pentynoate isomers
-
Topgi R., Ng J.S., Landis B., Wang P., and Behling J.R. Use of enzyme penicillin acylase in selective amidation/amide hydrolysis to resolve ethyl 3-amino-4-pentynoate isomers. Bioorg Med Chem 7 (1999) 2221-2229
-
(1999)
Bioorg Med Chem
, vol.7
, pp. 2221-2229
-
-
Topgi, R.1
Ng, J.S.2
Landis, B.3
Wang, P.4
Behling, J.R.5
-
4
-
-
0035806466
-
Highly efficient and enantioselective enzymatic acylation of amines in aqueous medium
-
Guranda D.T., van Langen L.M., van Rantwijk F., Sheldon R.A., and Svedas V.K. Highly efficient and enantioselective enzymatic acylation of amines in aqueous medium. Tetrahedron Asimmetry 12 (2001) 1645-1650
-
(2001)
Tetrahedron Asimmetry
, vol.12
, pp. 1645-1650
-
-
Guranda, D.T.1
van Langen, L.M.2
van Rantwijk, F.3
Sheldon, R.A.4
Svedas, V.K.5
-
5
-
-
0026596437
-
Enantioselective recognition of the phenalacetyl moiety in the Pen G acylase catalyzed hydrolysis of phenylacetate esters
-
Fuganti C., Rosell C.M., Servi S., Tagliani A., and Terreni M. Enantioselective recognition of the phenalacetyl moiety in the Pen G acylase catalyzed hydrolysis of phenylacetate esters. Tetrahedron Asimmetry 3 (1992) 383-386
-
(1992)
Tetrahedron Asimmetry
, vol.3
, pp. 383-386
-
-
Fuganti, C.1
Rosell, C.M.2
Servi, S.3
Tagliani, A.4
Terreni, M.5
-
6
-
-
0034595324
-
An enzyme-labile safety catch linker for combinatorial synthesis on a soluble polymeric support
-
Grether U., and Waldmann H. An enzyme-labile safety catch linker for combinatorial synthesis on a soluble polymeric support. Angew Chem Intl Ed 9 (2000) 629-632
-
(2000)
Angew Chem Intl Ed
, vol.9
, pp. 629-632
-
-
Grether, U.1
Waldmann, H.2
-
7
-
-
0027715307
-
Phenyacetyl group as enzyme cleavable aminoprotection of purine nucleosides
-
Dineva M.A., Galunsky B., Kashe V., and Petrov D.D. Phenyacetyl group as enzyme cleavable aminoprotection of purine nucleosides. Bioorg Med Chem Lett 12 (1993) 2781-2784
-
(1993)
Bioorg Med Chem Lett
, vol.12
, pp. 2781-2784
-
-
Dineva, M.A.1
Galunsky, B.2
Kashe, V.3
Petrov, D.D.4
-
8
-
-
0028857547
-
Penicillin acylase has a single-amino-acid catalytic centre
-
Duggleby H.J., Tolley S.P., Dodson C.P., Dodson E.J., and Moody P.C.E. Penicillin acylase has a single-amino-acid catalytic centre. Nature 373 (1995) 264-268
-
(1995)
Nature
, vol.373
, pp. 264-268
-
-
Duggleby, H.J.1
Tolley, S.P.2
Dodson, C.P.3
Dodson, E.J.4
Moody, P.C.E.5
-
10
-
-
36849031214
-
-
Clausen K, Dekkers RM. Process for the preparation of β-lactams at constantly high concentration of reactants. WP 9602663A1 (1999).
-
-
-
-
12
-
-
0028835759
-
The use of stabilised penicillin acylase derivatives improves the design of kinetically controlled synthesis
-
Fernandez-Lafuente R., Rosell C.M., and Guisan J.M. The use of stabilised penicillin acylase derivatives improves the design of kinetically controlled synthesis. J Mol Cat A 101 (1995) 91-97
-
(1995)
J Mol Cat A
, vol.101
, pp. 91-97
-
-
Fernandez-Lafuente, R.1
Rosell, C.M.2
Guisan, J.M.3
-
14
-
-
36849019431
-
-
Ulrich Eberhard G. An enzymatic process for preparing b-lactam. EP 1394262A1 (2004).
-
-
-
-
15
-
-
0031466064
-
One-pot chemoenzymatic synthesis of 3′-functionalized cephalosporines (Cefazolin) by three consecutive biotransformations in fully aqueous medium
-
Hernandez-Justiz O., Fernandez-Lafuente R., Guisan J.M., Negri P., Pagani G., Pregnolato M., et al. One-pot chemoenzymatic synthesis of 3′-functionalized cephalosporines (Cefazolin) by three consecutive biotransformations in fully aqueous medium. J Org Chem 62 (1997) 9099-9106
-
(1997)
J Org Chem
, vol.62
, pp. 9099-9106
-
-
Hernandez-Justiz, O.1
Fernandez-Lafuente, R.2
Guisan, J.M.3
Negri, P.4
Pagani, G.5
Pregnolato, M.6
-
16
-
-
0035903842
-
Modulation of penicillin acylase properties via immobilization techniques: one-pot chemoenzymatic synthesis of cephamandole from cephalosporin C
-
Terreni M., Pagani G., Ubiali D., Fernandez-Lafuente R., Mateo C., and Guisan J.M. Modulation of penicillin acylase properties via immobilization techniques: one-pot chemoenzymatic synthesis of cephamandole from cephalosporin C. Bioorg Med Chem Lett 11 (2001) 2429-2432
-
(2001)
Bioorg Med Chem Lett
, vol.11
, pp. 2429-2432
-
-
Terreni, M.1
Pagani, G.2
Ubiali, D.3
Fernandez-Lafuente, R.4
Mateo, C.5
Guisan, J.M.6
-
17
-
-
0026767204
-
Penicillin acylase mediate synthesis of formyl cefamandole
-
Fuganti C., Rosell C.M., Servi S., Tagliani A., and Terreni M. Penicillin acylase mediate synthesis of formyl cefamandole. Biotech Lett 14 (1992) 543-546
-
(1992)
Biotech Lett
, vol.14
, pp. 543-546
-
-
Fuganti, C.1
Rosell, C.M.2
Servi, S.3
Tagliani, A.4
Terreni, M.5
-
18
-
-
14644415440
-
Influence of substrate structure on PGA-catalyzed acylations. Evaluation of different approaches for the enzymatic synthesis of Cefonicid
-
Terreni M., Tchamkam J.G., Sarnataro U., Rocchietti S., Fernandez-Lafuente R., and Guisan J.M. Influence of substrate structure on PGA-catalyzed acylations. Evaluation of different approaches for the enzymatic synthesis of Cefonicid. Adv Synth Catal 347 (2005) 121-128
-
(2005)
Adv Synth Catal
, vol.347
, pp. 121-128
-
-
Terreni, M.1
Tchamkam, J.G.2
Sarnataro, U.3
Rocchietti, S.4
Fernandez-Lafuente, R.5
Guisan, J.M.6
-
19
-
-
0027155750
-
Inactivation of penicillin acylase from Kluyvera citrophila by N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline: a case of time-dependent non-covalent enzyme inhibition
-
Martin J., Manchego J.M., and Arche R. Inactivation of penicillin acylase from Kluyvera citrophila by N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline: a case of time-dependent non-covalent enzyme inhibition. Biochem J 291 (1993) 907-914
-
(1993)
Biochem J
, vol.291
, pp. 907-914
-
-
Martin, J.1
Manchego, J.M.2
Arche, R.3
-
20
-
-
0021474972
-
Phenylalkylsulfonyl derivatives as covalent inhibitors of penicillin amidase
-
Siewiinsky M., and Kuropatwa M. Phenylalkylsulfonyl derivatives as covalent inhibitors of penicillin amidase. Hoppe-Seyeŕs Z Physiol Chem 635 (1984) 829-837
-
(1984)
Hoppe-Seyeŕs Z Physiol Chem
, vol.635
, pp. 829-837
-
-
Siewiinsky, M.1
Kuropatwa, M.2
-
21
-
-
0032524016
-
Modulation of the properties of penicillin G acylase by acyl donor substrates during n-protection of amino compounds
-
Fernandez-Lafuente R., Rosell C.M., and Guisan J.M. Modulation of the properties of penicillin G acylase by acyl donor substrates during n-protection of amino compounds. Enzyme Microb Tech 22 (1998) 583-587
-
(1998)
Enzyme Microb Tech
, vol.22
, pp. 583-587
-
-
Fernandez-Lafuente, R.1
Rosell, C.M.2
Guisan, J.M.3
-
22
-
-
0141908147
-
Enzyme distribution derived from macroscopic particle behavior of an industrial immobilized penicillin-G acylase
-
van Roon J.L., Joerink M., Rijkers M., Tramper J., Schroen C., and Beeftink H. Enzyme distribution derived from macroscopic particle behavior of an industrial immobilized penicillin-G acylase. Biotechnol Prog 19 (2003) 1510-1518
-
(2003)
Biotechnol Prog
, vol.19
, pp. 1510-1518
-
-
van Roon, J.L.1
Joerink, M.2
Rijkers, M.3
Tramper, J.4
Schroen, C.5
Beeftink, H.6
-
23
-
-
36849093878
-
-
De Vroom E. An improved immobilized penicillin G acylase. WP 9704086A1 (1997).
-
-
-
-
24
-
-
20544476972
-
Immobilization of penicillin G acylase: the key to optimum performance
-
Kallenberg A.I., Van Rantwijk F., and Sheldon R.A. Immobilization of penicillin G acylase: the key to optimum performance. Adv Synth Catal 347 (2005) 905-926
-
(2005)
Adv Synth Catal
, vol.347
, pp. 905-926
-
-
Kallenberg, A.I.1
Van Rantwijk, F.2
Sheldon, R.A.3
-
25
-
-
0036644256
-
Influence of the enzyme derivative preparation and substrate structure on the enantioselectivity of penicillin G acylase
-
Rocchietti S., San Vincente Urrutia A., Pregnolato M., Tagliani A., Guisan J.M., Fernandez-Lafuente R., et al. Influence of the enzyme derivative preparation and substrate structure on the enantioselectivity of penicillin G acylase. Enzyme Microb Tech 31 (2002) 88-93
-
(2002)
Enzyme Microb Tech
, vol.31
, pp. 88-93
-
-
Rocchietti, S.1
San Vincente Urrutia, A.2
Pregnolato, M.3
Tagliani, A.4
Guisan, J.M.5
Fernandez-Lafuente, R.6
-
27
-
-
22044436655
-
Some special features of glyoxyl supports to immobilize proteins
-
Mateo C., Abian O., Bernedo M., Cuenca E., Fuentes M., Fernandez-Lorente G., et al. Some special features of glyoxyl supports to immobilize proteins. Enzyme Microb Technol 37 (2005) 456-462
-
(2005)
Enzyme Microb Technol
, vol.37
, pp. 456-462
-
-
Mateo, C.1
Abian, O.2
Bernedo, M.3
Cuenca, E.4
Fuentes, M.5
Fernandez-Lorente, G.6
-
28
-
-
33645282523
-
Glyoxyl agarose as a new chromatographic matrix
-
Grazú V., Betancor L., Montes T., Lopez-Gallego F., Guisan J.M., and Fernandez-Lafuente R. Glyoxyl agarose as a new chromatographic matrix. Enzyme Microb Technol 38 (2006) 960-966
-
(2006)
Enzyme Microb Technol
, vol.38
, pp. 960-966
-
-
Grazú, V.1
Betancor, L.2
Montes, T.3
Lopez-Gallego, F.4
Guisan, J.M.5
Fernandez-Lafuente, R.6
-
29
-
-
33646500582
-
Glyoxyl agarose: a fully inert and hydrophilic support for immobilization and high stabilization of proteins
-
Mateo C., Palomo J.M., Fuentes M., Betancor L., Grazú V., Lopez-Gallego F., et al. Glyoxyl agarose: a fully inert and hydrophilic support for immobilization and high stabilization of proteins. Enzyme Micro Technol 39 (2006) 274-280
-
(2006)
Enzyme Micro Technol
, vol.39
, pp. 274-280
-
-
Mateo, C.1
Palomo, J.M.2
Fuentes, M.3
Betancor, L.4
Grazú, V.5
Lopez-Gallego, F.6
-
30
-
-
0033042026
-
Salt-induced immobilization of affinity ligands onto epoxide-activated supports
-
Wheatley J.B., Schmidt Jr., and Donald E. Salt-induced immobilization of affinity ligands onto epoxide-activated supports. J Chromatogr A 849 (1999) 1-12
-
(1999)
J Chromatogr A
, vol.849
, pp. 1-12
-
-
Wheatley, J.B.1
Schmidt, Jr.2
Donald, E.3
-
31
-
-
0027326779
-
Salt induced immobilization of proteins on high-performance liquid chromatographic epoxide affinity support
-
Wheatley J.B., and Schmidt D.E. Salt induced immobilization of proteins on high-performance liquid chromatographic epoxide affinity support. J Chromatogr A 644 (1993) 11-16
-
(1993)
J Chromatogr A
, vol.644
, pp. 11-16
-
-
Wheatley, J.B.1
Schmidt, D.E.2
-
32
-
-
0034575018
-
Multifunctional epoxy supports: a new tool to improve the covalent immobilization of proteins. The promotion of physical adsorptions of proteins on the supports before their covalent linkage
-
Mateo C., Fernández-Lorente G., Abian O., Fernández-Lafuente R., and Guisán J.M. Multifunctional epoxy supports: a new tool to improve the covalent immobilization of proteins. The promotion of physical adsorptions of proteins on the supports before their covalent linkage. Biomocromolecules 1 (2000) 739-745
-
(2000)
Biomocromolecules
, vol.1
, pp. 739-745
-
-
Mateo, C.1
Fernández-Lorente, G.2
Abian, O.3
Fernández-Lafuente, R.4
Guisán, J.M.5
-
33
-
-
0034111128
-
Increase in conformational stability of enzymes immobilized on epoxy-activated supports by favoring additional multipoint covalent attachment
-
Mateo C., Abian O., Fernández-Lafuente R., and Guisán J.M. Increase in conformational stability of enzymes immobilized on epoxy-activated supports by favoring additional multipoint covalent attachment. Enzyme Microb Technol 26 (2000) 509-515
-
(2000)
Enzyme Microb Technol
, vol.26
, pp. 509-515
-
-
Mateo, C.1
Abian, O.2
Fernández-Lafuente, R.3
Guisán, J.M.4
-
34
-
-
0035988098
-
Epoxy sepabeads: a novel epoxy support for stabilization of industrial enzymes via very intense multipoint covalent attachment
-
Mateo C., Abian O., Fernández-Lorente G., Predoche J., Fernández-Lafuente R., and Guisan J.M. Epoxy sepabeads: a novel epoxy support for stabilization of industrial enzymes via very intense multipoint covalent attachment. Biotechnol Prog 18 (2002) 629-634
-
(2002)
Biotechnol Prog
, vol.18
, pp. 629-634
-
-
Mateo, C.1
Abian, O.2
Fernández-Lorente, G.3
Predoche, J.4
Fernández-Lafuente, R.5
Guisan, J.M.6
-
35
-
-
0024029957
-
Aldehyde-agarose gels as activated supports for immobilization-stabilization of enzymes
-
Guisan J.M. Aldehyde-agarose gels as activated supports for immobilization-stabilization of enzymes. Enzyme Microb Technol 10 (1988) 375-382
-
(1988)
Enzyme Microb Technol
, vol.10
, pp. 375-382
-
-
Guisan, J.M.1
-
36
-
-
0035850792
-
Crystal structures of penicillin acylase enzyme-substrate complexes: structural insights into the catalytic mechanism
-
McVey C.E., Walsh M.A., Dodson G.G., Wilson K.S., and Brannigan J.A.J. Crystal structures of penicillin acylase enzyme-substrate complexes: structural insights into the catalytic mechanism. J Mol Biol 313 (2001) 139-150
-
(2001)
J Mol Biol
, vol.313
, pp. 139-150
-
-
McVey, C.E.1
Walsh, M.A.2
Dodson, G.G.3
Wilson, K.S.4
Brannigan, J.A.J.5
-
37
-
-
0018088319
-
Substrate specificity of penicillin acylase of E. coli
-
Plaskie A., Roets E., and Vanderhaeghe H. Substrate specificity of penicillin acylase of E. coli. J Antibiot 31 (1978) 783-788
-
(1978)
J Antibiot
, vol.31
, pp. 783-788
-
-
Plaskie, A.1
Roets, E.2
Vanderhaeghe, H.3
-
38
-
-
0002426489
-
Compounds related to the steroid hormones. XV. Proton magnetic resonance spectra of 11-oxo-steroids
-
Green G.F.H., Page J.E., and Staniforth S.E. Compounds related to the steroid hormones. XV. Proton magnetic resonance spectra of 11-oxo-steroids. J Chem Soc 65 (1965) 1595-1605
-
(1965)
J Chem Soc
, vol.65
, pp. 1595-1605
-
-
Green, G.F.H.1
Page, J.E.2
Staniforth, S.E.3
-
39
-
-
0039826117
-
The X-ray analysis of the structure of cephalosporin C
-
Hodgkin D.C., and Maslen E.N. The X-ray analysis of the structure of cephalosporin C. Biochem J 79 (1961) 393-402
-
(1961)
Biochem J
, vol.79
, pp. 393-402
-
-
Hodgkin, D.C.1
Maslen, E.N.2
-
40
-
-
0014938290
-
Molecular architecture of the cephalosporins. Insights into biological activity based on structural investigation
-
Sweet R.M., and Dahl L.F. Molecular architecture of the cephalosporins. Insights into biological activity based on structural investigation. J Am Chem Soc 92 (1970) 5489-5507
-
(1970)
J Am Chem Soc
, vol.92
, pp. 5489-5507
-
-
Sweet, R.M.1
Dahl, L.F.2
-
41
-
-
0036237518
-
The role of hydrophobic active-site residues in substrate specificity and acyl transfer activity of penicillin acylase
-
Alkema W.B.L., Dijkhuis A.J., de Vries E., and Janssen D.B. The role of hydrophobic active-site residues in substrate specificity and acyl transfer activity of penicillin acylase. Eur J Biochem 269 (2002) 2093-2100
-
(2002)
Eur J Biochem
, vol.269
, pp. 2093-2100
-
-
Alkema, W.B.L.1
Dijkhuis, A.J.2
de Vries, E.3
Janssen, D.B.4
-
42
-
-
2942577464
-
Kinetic studies and molecular modelling attribute a crucial role in the specificity and stereoselectivity of penicillin acylase to the pair ArgA145-ArgB263
-
Guncheva M., Ivanov I., Galunsky B., Stambolieva N., and Kaneti J. Kinetic studies and molecular modelling attribute a crucial role in the specificity and stereoselectivity of penicillin acylase to the pair ArgA145-ArgB263. Eur J Biochem 271 (2004) 2272-2279
-
(2004)
Eur J Biochem
, vol.271
, pp. 2272-2279
-
-
Guncheva, M.1
Ivanov, I.2
Galunsky, B.3
Stambolieva, N.4
Kaneti, J.5
-
43
-
-
0033550299
-
Salt bridge stability in monomeric proteins
-
Kumar S., and Nussinov R. Salt bridge stability in monomeric proteins. J Mol Biol 293 (1999) 1241-1255
-
(1999)
J Mol Biol
, vol.293
, pp. 1241-1255
-
-
Kumar, S.1
Nussinov, R.2
-
44
-
-
0032189174
-
The presence of methanol exerts a strong and complex modulation of the synthesis of different antibiotics by immobilized penicillin G acylase
-
Fernandez-Lafuente R., Rosell C.M., and Guisan J.M. The presence of methanol exerts a strong and complex modulation of the synthesis of different antibiotics by immobilized penicillin G acylase. Enzyme Microb Technol 23 (1998) 305-310
-
(1998)
Enzyme Microb Technol
, vol.23
, pp. 305-310
-
-
Fernandez-Lafuente, R.1
Rosell, C.M.2
Guisan, J.M.3
-
45
-
-
0343446120
-
Synthesis of antibiotics (cephaloglycin) catalyzed by penicillin G acylase: evaluation and optimization of different synthetic approaches
-
Fernandez-Lafuente R., Rosell C.M., Piatkowska B., and Guisan J.M. Synthesis of antibiotics (cephaloglycin) catalyzed by penicillin G acylase: evaluation and optimization of different synthetic approaches. Enzyme Microb Technol 19 (1996) 9-14
-
(1996)
Enzyme Microb Technol
, vol.19
, pp. 9-14
-
-
Fernandez-Lafuente, R.1
Rosell, C.M.2
Piatkowska, B.3
Guisan, J.M.4
-
46
-
-
0030568517
-
Penicillin acylase-catalyzed synthesis of pivampicillin: effect of reaction variables and organic cosolvents
-
Kim M.G., and Lee S.B. Penicillin acylase-catalyzed synthesis of pivampicillin: effect of reaction variables and organic cosolvents. J Mol Cat B: Enzym 1 (1996) 71-80
-
(1996)
J Mol Cat B: Enzym
, vol.1
, pp. 71-80
-
-
Kim, M.G.1
Lee, S.B.2
-
47
-
-
0030568593
-
Effect of organic solvents on penicillin acylase-catalyzed reactions: interaction of organic solvents with enzymes
-
Kim M.G., and Lee S.B. Effect of organic solvents on penicillin acylase-catalyzed reactions: interaction of organic solvents with enzymes. J Mol Cat B: Enzym 1 (1996) 181-190
-
(1996)
J Mol Cat B: Enzym
, vol.1
, pp. 181-190
-
-
Kim, M.G.1
Lee, S.B.2
-
48
-
-
0030568603
-
Penicillin acylase-catalyzed synthesis of β-lactam antibiotics in water-methanol mixtures: effect of cosolvent content and chemical nature of substrate on reaction rates and yields
-
Kim M.G., and Lee S.B. Penicillin acylase-catalyzed synthesis of β-lactam antibiotics in water-methanol mixtures: effect of cosolvent content and chemical nature of substrate on reaction rates and yields. J Mol Cat B: Enzym 1 (1996) 201-211
-
(1996)
J Mol Cat B: Enzym
, vol.1
, pp. 201-211
-
-
Kim, M.G.1
Lee, S.B.2
-
49
-
-
0031573245
-
Improving the activity of immobilized subtilisin by site-specific attachment to surfaces
-
Huang W., Wang J.Q., Bhattacharyya D., and Bachas L.G. Improving the activity of immobilized subtilisin by site-specific attachment to surfaces. Anal Chem 69 (1997) 4601-4607
-
(1997)
Anal Chem
, vol.69
, pp. 4601-4607
-
-
Huang, W.1
Wang, J.Q.2
Bhattacharyya, D.3
Bachas, L.G.4
|