-
1
-
-
0032211043
-
The optimization of penicillin biosynthesis in fungi
-
Penalva, M. A., Rowlands, R. T., and Turner, G.: The optimization of penicillin biosynthesis in fungi. Trends Biotechnol., 16, 483-489 (1998).
-
(1998)
Trends Biotechnol.
, vol.16
, pp. 483-489
-
-
Penalva, M.A.1
Rowlands, R.T.2
Turner, G.3
-
2
-
-
0026086202
-
The role of penicillin amidases in nature and in industry
-
Valle, F., Balbas, P., Merino, E., and Bolivar, F.: The role of penicillin amidases in nature and in industry. Trends Biochem. Sci., 16, 36-40 (1991).
-
(1991)
Trends Biochem. Sci.
, vol.16
, pp. 36-40
-
-
Valle, F.1
Balbas, P.2
Merino, E.3
Bolivar, F.4
-
3
-
-
0028095969
-
Molecular biology of β-lactam acylases
-
Deshpande, B. S., Ambedkar, S. S., Sudhakaran, V. K., and Shewale, J. G.: Molecular biology of β-lactam acylases. World J. Microbiol. Biotechnol., 10, 129-138 (1994).
-
(1994)
World J. Microbiol. Biotechnol.
, vol.10
, pp. 129-138
-
-
Deshpande, B.S.1
Ambedkar, S.S.2
Sudhakaran, V.K.3
Shewale, J.G.4
-
4
-
-
0002100485
-
Immobilized biocatalysts and antibiotic production: Biochemical, genetical and biotechnical aspects
-
Moo-Young, M. (ed.), Marcel Dekker, New York
-
Vandamme, E. J.: Immobilized biocatalysts and antibiotic production: biochemical, genetical and biotechnical aspects, p. 261-286. In Moo-Young, M. (ed.), Immobilized enzymes and cells: fundamentals and applications. Marcel Dekker, New York (1988).
-
(1988)
Immobilized Enzymes and Cells: Fundamentals and Applications
, pp. 261-286
-
-
Vandamme, E.J.1
-
5
-
-
0031149064
-
Penicillin V acylase: Its potential in the production of 6-aminopenicillanic acid
-
Shewale, J. G. and Sudhakaran, V. K.: Penicillin V acylase: its potential in the production of 6-aminopenicillanic acid. Enzyme Microb. Technol., 20, 402-410 (1997).
-
(1997)
Enzyme Microb. Technol.
, vol.20
, pp. 402-410
-
-
Shewale, J.G.1
Sudhakaran, V.K.2
-
6
-
-
0014642629
-
Hydrolysis of penicillins and related compounds by the cell-bound penicillin acylase of Escherichia coli
-
Cole, M.: Hydrolysis of penicillins and related compounds by the cell-bound penicillin acylase of Escherichia coli. Biochem. J., 115, 733-739 (1969).
-
(1969)
Biochem. J.
, vol.115
, pp. 733-739
-
-
Cole, M.1
-
7
-
-
0022870084
-
Complete nucleotide sequence of the penicillin acylase from Kluyvera citrophila
-
Barbero, J. L., Buesa, J. M., Buitrago, G. G., Mendez, E., Perez-Aranda, A., and Garcia, J. L.: Complete nucleotide sequence of the penicillin acylase from Kluyvera citrophila. Gene, 49, 69-80 (1986).
-
(1986)
Gene
, vol.49
, pp. 69-80
-
-
Barbero, J.L.1
Buesa, J.M.2
Buitrago, G.G.3
Mendez, E.4
Perez-Aranda, A.5
Garcia, J.L.6
-
8
-
-
0028965854
-
Purification and preliminary crystallographic studies of penicillin G acylase from Providencia rettgeri
-
Kiel, H. E., Daumy, G. O., and Kelly, J. A.: Purification and preliminary crystallographic studies of penicillin G acylase from Providencia rettgeri. Protein Sci., 4, 433-441 (1995).
-
(1995)
Protein Sci.
, vol.4
, pp. 433-441
-
-
Kiel, H.E.1
Daumy, G.O.2
Kelly, J.A.3
-
9
-
-
0030882016
-
Molecular cloning and analysis of the gene encoding the thermostable penicillin G acylase from Alcaligenes faecalis
-
Verhaert, R. M. D., Riemens, A. M., Laan, J., Duin, J., and Quax, W. J.: Molecular cloning and analysis of the gene encoding the thermostable penicillin G acylase from Alcaligenes faecalis. Appl. Environ. Microbiol., 63, 3412-3418 (1997).
-
(1997)
Appl. Environ. Microbiol.
, vol.63
, pp. 3412-3418
-
-
Verhaert, R.M.D.1
Riemens, A.M.2
Laan, J.3
Duin, J.4
Quax, W.J.5
-
10
-
-
0024354782
-
Expression of the Arthrobacter viscosus penicillin acylase gene in Escherichia coli and Bacillus subtilis
-
Ohashi, H., Katsuta, Y., Nagashima, M., Kamei, T., and Yano, M.: Expression of the Arthrobacter viscosus penicillin acylase gene in Escherichia coli and Bacillus subtilis. Appl. Environ. Microbiol., 55, 351-356 (1989).
-
(1989)
Appl. Environ. Microbiol.
, vol.55
, pp. 351-356
-
-
Ohashi, H.1
Katsuta, Y.2
Nagashima, M.3
Kamei, T.4
Yano, M.5
-
11
-
-
0014035567
-
Purification and properties of penicillin acylases from Bacillus megaterium
-
Chiang, C. and Bennett, R. E.: Purification and properties of penicillin acylases from Bacillus megaterium. J. Bacteriol., 93, 302-308 (1967).
-
(1967)
J. Bacteriol.
, vol.93
, pp. 302-308
-
-
Chiang, C.1
Bennett, R.E.2
-
12
-
-
0036364670
-
Optimization of a fermentation medium for the production of penicillin G acylase from Bacillus sp.
-
Rajendbran, J., Krishnakumar, V., and Gunasekaran, P.: Optimization of a fermentation medium for the production of penicillin G acylase from Bacillus sp. Lett. Appl. Microbiol., 35, 523-527 (2002).
-
(2002)
Lett. Appl. Microbiol.
, vol.35
, pp. 523-527
-
-
Rajendbran, J.1
Krishnakumar, V.2
Gunasekaran, P.3
-
13
-
-
0030029182
-
Molecular characterization of the 4-hydroxyphenylacetate catabolic pathway of Escherichia coli W: Engineering a mobile aromatic degradative cluster
-
Prieto, M. A., Diaz, E., and Garcia, J. L.: Molecular characterization of the 4-hydroxyphenylacetate catabolic pathway of Escherichia coli W: engineering a mobile aromatic degradative cluster. J. Bacteriol., 178, 111-120 (1996).
-
(1996)
J. Bacteriol.
, vol.178
, pp. 111-120
-
-
Prieto, M.A.1
Diaz, E.2
Garcia, J.L.3
-
14
-
-
0028972449
-
A protein catalytic framework with an N-terminal nucleophile is capable of self-activation
-
Brannigan, J. A., Dodson, G., Duggleby, H. J., Moody, P. C., Smith, J. L., Tomchick, D. R., and Murzin, A. G.: A protein catalytic framework with an N-terminal nucleophile is capable of self-activation. Nature, 378, 416-419 (1995).
-
(1995)
Nature
, vol.378
, pp. 416-419
-
-
Brannigan, J.A.1
Dodson, G.2
Duggleby, H.J.3
Moody, P.C.4
Smith, J.L.5
Tomchick, D.R.6
Murzin, A.G.7
-
15
-
-
0028857547
-
Penicillin acylase has a single-amino-acid catalytic centre
-
Duggleby, H. J., Tolley, S. P., Hill, C. P., Dodson, E. J., Dodson, G., and Moody, P. C.: Penicillin acylase has a single-amino-acid catalytic centre. Nature, 373, 264-268 (1995).
-
(1995)
Nature
, vol.373
, pp. 264-268
-
-
Duggleby, H.J.1
Tolley, S.P.2
Hill, C.P.3
Dodson, E.J.4
Dodson, G.5
Moody, P.C.6
-
16
-
-
0002345437
-
Penicillin acylases: Application and potentials
-
Shewale, J. G., Deshpande, B. S., Sudhakaran, V. K., and Ambedkar, S. S.: Penicillin acylases: application and potentials. Process Biochem., 25, 97-103 (1990).
-
(1990)
Process Biochem.
, vol.25
, pp. 97-103
-
-
Shewale, J.G.1
Deshpande, B.S.2
Sudhakaran, V.K.3
Ambedkar, S.S.4
-
17
-
-
0026705620
-
Carbon regulation and the role in nature of the Escherichia coli penicillin acylase (pac) gene
-
Merino, E., Balbas, P., Recillas, F., Becerril, B., Valle, F., and Bolivar, F.: Carbon regulation and the role in nature of the Escherichia coli penicillin acylase (pac) gene. Mol. Microbiol., 6, 2175-2182 (1992).
-
(1992)
Mol. Microbiol.
, vol.6
, pp. 2175-2182
-
-
Merino, E.1
Balbas, P.2
Recillas, F.3
Becerril, B.4
Valle, F.5
Bolivar, F.6
-
18
-
-
0030809762
-
Location of regulatory gene in penicillin G acylase operon (pacR) of E. coli D816
-
Jiang, L., Wang, Y., and Yang, S.: Location of regulatory gene in penicillin G acylase operon (pacR) of E. coli D816. Genet. Anal., 14, 51-54 (1997).
-
(1997)
Genet. Anal.
, vol.14
, pp. 51-54
-
-
Jiang, L.1
Wang, Y.2
Yang, S.3
-
19
-
-
0032797410
-
New insights into the regulation of the pac gene from Escherichia coli W ATCC 11105
-
Rao, A. and Garcia, J. L.: New insights into the regulation of the pac gene from Escherichia coli W ATCC 11105. FEMS Microbiol. Lett., 177, 7-14 (1999).
-
(1999)
FEMS Microbiol. Lett.
, vol.177
, pp. 7-14
-
-
Rao, A.1
Garcia, J.L.2
-
20
-
-
0022897997
-
Characterization of the regulatory region of the Escherichia coli penicillin acylase gene
-
Valle, F., Gosset, G., Tenorio, B., Oliver, G., and Bolivar, F.: Characterization of the regulatory region of the Escherichia coli penicillin acylase gene. Gene, 50, 119-122 (1986).
-
(1986)
Gene
, vol.50
, pp. 119-122
-
-
Valle, F.1
Gosset, G.2
Tenorio, B.3
Oliver, G.4
Bolivar, F.5
-
21
-
-
0016416484
-
Penicillin acylase (bacterial)
-
Savidge, T. A. and Cole, M.: Penicillin acylase (bacterial). Methods Enzymol., 43, 705-721 (1975).
-
(1975)
Methods Enzymol.
, vol.43
, pp. 705-721
-
-
Savidge, T.A.1
Cole, M.2
-
22
-
-
0023481348
-
Complete nucleotide sequence of the penicillin G acylase gene and flanking regions, and its expression in Escherichia coli
-
Oh, S. J., Kim, Y. C., Park, Y. W., Min, S. Y., Kim, I. S., and Kang, H. S.: Complete nucleotide sequence of the penicillin G acylase gene and flanking regions, and its expression in Escherichia coli. Gene, 56, 87-97 (1987).
-
(1987)
Gene
, vol.56
, pp. 87-97
-
-
Oh, S.J.1
Kim, Y.C.2
Park, Y.W.3
Min, S.Y.4
Kim, I.S.5
Kang, H.S.6
-
23
-
-
0025955658
-
Refolding and assembly of penicillin acylase, an enzyme composed of two polypeptide chains that result from proteolytic activation
-
Lindsay, C. D. and Pain, R. H.: Refolding and assembly of penicillin acylase, an enzyme composed of two polypeptide chains that result from proteolytic activation. Biochemistry, 30, 9034-9040 (1991).
-
(1991)
Biochemistry
, vol.30
, pp. 9034-9040
-
-
Lindsay, C.D.1
Pain, R.H.2
-
24
-
-
0034548901
-
Genetic strategies to enhance penicillin acylase production in Escherichia coli
-
Chou, C. P., Lin, W., Kuo, B., and Yu, C.: Genetic strategies to enhance penicillin acylase production in Escherichia coli. Enzyme Microb. Technol., 27, 766-773 (2000).
-
(2000)
Enzyme Microb. Technol.
, vol.27
, pp. 766-773
-
-
Chou, C.P.1
Lin, W.2
Kuo, B.3
Yu, C.4
-
25
-
-
0035084965
-
Expression of penicillin G acylase from the cloned pac gene of Escherichia coli ATCC 11105. Effects of pacR and temperature
-
Dai, M., Zhu, Y., Yang, Y., Wang, E., Xie, Y., Zhao, G., and Jiang, W.: Expression of penicillin G acylase from the cloned pac gene of Escherichia coli ATCC 11105. Effects of pacR and temperature. Eur. J. Biochem., 268, 1298-1303 (2001).
-
(2001)
Eur. J. Biochem.
, vol.268
, pp. 1298-1303
-
-
Dai, M.1
Zhu, Y.2
Yang, Y.3
Wang, E.4
Xie, Y.5
Zhao, G.6
Jiang, W.7
-
26
-
-
0343488839
-
Identification of the pac promoter from Kluyvera citrophila
-
Rao, A. and Garcia, J. L.: Identification of the pac promoter from Kluyvera citrophila. FEMS Microbiol. Lett., 151, 9-16 (1997).
-
(1997)
FEMS Microbiol. Lett.
, vol.151
, pp. 9-16
-
-
Rao, A.1
Garcia, J.L.2
-
27
-
-
0020403459
-
Repression of penicillin G acylase of Proteus rettgeri by tricarboxylic acid cycle intermediates
-
Daumy, G. O., McColl, A. S., and Apostolakos, D.: Repression of penicillin G acylase of Proteus rettgeri by tricarboxylic acid cycle intermediates. J. Bacteriol., 152, 104-110 (1982).
-
(1982)
J. Bacteriol.
, vol.152
, pp. 104-110
-
-
Daumy, G.O.1
McColl, A.S.2
Apostolakos, D.3
-
28
-
-
0025868862
-
Purification and kinetics of penicillin G acylase from a mutant strain of Escherichia coli ATCC 11105
-
Erarslan, A., Terzi, I., Guray, A., and Bermek, E.: Purification and kinetics of penicillin G acylase from a mutant strain of Escherichia coli ATCC 11105. J. Chem. Technol. Biotechnol., 51, 27-40 (1991).
-
(1991)
J. Chem. Technol. Biotechnol.
, vol.51
, pp. 27-40
-
-
Erarslan, A.1
Terzi, I.2
Guray, A.3
Bermek, E.4
-
29
-
-
0000903228
-
Penicillin acylase: Enzyme production and its application in the manufacture of 6-APA
-
Shewale, J. G. and Sivaraman, H.: Penicillin acylase: enzyme production and its application in the manufacture of 6-APA. Process Biochem., 24, 146-154 (1989).
-
(1989)
Process Biochem.
, vol.24
, pp. 146-154
-
-
Shewale, J.G.1
Sivaraman, H.2
-
30
-
-
0022362447
-
Experimental evolution of penicillin G acylase from Escherichia coli and Proteus rettgeri
-
Daumy, G. O., Danley, D., McColl, A. S., Apostolakos, D., and Vinick, F. J.: Experimental evolution of penicillin G acylase from Escherichia coli and Proteus rettgeri. J. Bacteriol., 163, 925-932 (1985).
-
(1985)
J. Bacteriol.
, vol.163
, pp. 925-932
-
-
Daumy, G.O.1
Danley, D.2
McColl, A.S.3
Apostolakos, D.4
Vinick, F.J.5
-
31
-
-
0028982367
-
Cloning of penicillin G acylase-encoding gene from Escherichia coli high-producing strain RE3
-
Sobotkova, L., Stepanek, V., Plhackova, K., and Kyslik, P.: Cloning of penicillin G acylase-encoding gene from Escherichia coli high-producing strain RE3. Biotechnol. Lett., 17, 723-728 (1995).
-
(1995)
Biotechnol. Lett.
, vol.17
, pp. 723-728
-
-
Sobotkova, L.1
Stepanek, V.2
Plhackova, K.3
Kyslik, P.4
-
32
-
-
0033526409
-
Genetic manipulation to identify limiting steps and develop strategies for high-level expression of penicillin acylase Escherichia coli
-
Chou, C. P., Yu, C., Tseng, J., Lin, M., and Lin, H.: Genetic manipulation to identify limiting steps and develop strategies for high-level expression of penicillin acylase Escherichia coli. Biotechnol. Bioeng., 63, 263-272 (1999).
-
(1999)
Biotechnol. Bioeng.
, vol.63
, pp. 263-272
-
-
Chou, C.P.1
Yu, C.2
Tseng, J.3
Lin, M.4
Lin, H.5
-
33
-
-
0022450984
-
Expression and regulation of the penicillin G acylase gene from Proteus rettgeri cloned in Escherichia coli
-
Daumy, G. O., Williams, J. A., McColl, A. S., Zuzel, T. J., and Danley, D.: Expression and regulation of the penicillin G acylase gene from Proteus rettgeri cloned in Escherichia coli. J. Bacteriol., 168, 431-433 (1986).
-
(1986)
J. Bacteriol.
, vol.168
, pp. 431-433
-
-
Daumy, G.O.1
Williams, J.A.2
McColl, A.S.3
Zuzel, T.J.4
Danley, D.5
-
34
-
-
0023149799
-
Cloning and expression of penicillin acylase genes from over producing strains of Escherichia coli and Bacillus megaterium
-
Meevootisom, V. and Saunders, J. R.: Cloning and expression of penicillin acylase genes from over producing strains of Escherichia coli and Bacillus megaterium. Appl. Microbiol. Biotechnol., 25, 372-373 (1987).
-
(1987)
Appl. Microbiol. Biotechnol.
, vol.25
, pp. 372-373
-
-
Meevootisom, V.1
Saunders, J.R.2
-
35
-
-
0028959277
-
Cloning and sequencing of the pac gene encoding the penicillin G acylase of Bacillus megaterium ATCC 14945
-
Martin, L., Prieto, M. A., Cortes, E., and Garcia, J. L.: Cloning and sequencing of the pac gene encoding the penicillin G acylase of Bacillus megaterium ATCC 14945. FEMS Microbiol. Lett., 125, 287-292 (1995).
-
(1995)
FEMS Microbiol. Lett.
, vol.125
, pp. 287-292
-
-
Martin, L.1
Prieto, M.A.2
Cortes, E.3
Garcia, J.L.4
-
36
-
-
0021148188
-
Instability of the plasmid carrying active penicillin acylase gene from Escherichia coli: Conditions inducing insertional inactivation
-
Deretic, V., Francetic, O., and Glisin, V.: Instability of the plasmid carrying active penicillin acylase gene from Escherichia coli: conditions inducing insertional inactivation. FEMS Microbiol. Lett., 24, 173-177 (1984).
-
(1984)
FEMS Microbiol. Lett.
, vol.24
, pp. 173-177
-
-
Deretic, V.1
Francetic, O.2
Glisin, V.3
-
37
-
-
0035048895
-
Enhanced production of penicillin G acylase from a recombinant Escherichia coli
-
Vohra, P. K., Sharma, R., Kashyap, D. R., and Tewari, R.: Enhanced production of penicillin G acylase from a recombinant Escherichia coli. Biotechnol. Lett., 23, 531-535 (2001).
-
(2001)
Biotechnol. Lett.
, vol.23
, pp. 531-535
-
-
Vohra, P.K.1
Sharma, R.2
Kashyap, D.R.3
Tewari, R.4
-
38
-
-
0033867249
-
High expression of the penicillin G acylase gene (pac) from Bacillus megaterium UN 1 in its own pac minus mutant
-
Panbangred, W., Weeradechapon, K., Udomvaraphant, S., Fujiyama, K., and Meevootisom, V.: High expression of the penicillin G acylase gene (pac) from Bacillus megaterium UN 1 in its own pac minus mutant. J. Appl. Microbiol., 89, 152-157 (2000).
-
(2000)
J. Appl. Microbiol.
, vol.89
, pp. 152-157
-
-
Panbangred, W.1
Weeradechapon, K.2
Udomvaraphant, S.3
Fujiyama, K.4
Meevootisom, V.5
-
39
-
-
0034951829
-
Expression and purification of extracellular penicillin G acylase in Bacillus subtilis
-
Yang, S., Huang, H., Zhang, R., Huang, X., Li, S., and Yuan, Z.: Expression and purification of extracellular penicillin G acylase in Bacillus subtilis. Protein Expr. Purif., 21, 60-64 (2001).
-
(2001)
Protein Expr. Purif.
, vol.21
, pp. 60-64
-
-
Yang, S.1
Huang, H.2
Zhang, R.3
Huang, X.4
Li, S.5
Yuan, Z.6
-
40
-
-
0025960114
-
Expression of penicillin G acylase from Bacillus megaterium ATCC 14945 in Escherichia coli and Bacillus subtilis
-
Kang, J. H., Hwang, Y., and Yoo, O. J.: Expression of penicillin G acylase from Bacillus megaterium ATCC 14945 in Escherichia coli and Bacillus subtilis. J. Biotechnol., 17, 99-108 (1991).
-
(1991)
J. Biotechnol.
, vol.17
, pp. 99-108
-
-
Kang, J.H.1
Hwang, Y.2
Yoo, O.J.3
-
41
-
-
0030916974
-
Localization and characterization of inclusion bodies in recombinant Escherichia coli cells over-producing penicillin G acylase
-
Sriubolmas, N., Panbangred, W., Sriurairatana, S., and Meevootisom, V.: Localization and characterization of inclusion bodies in recombinant Escherichia coli cells over-producing penicillin G acylase. Appl. Microbiol. Biotechnol., 47, 373-378 (1997).
-
(1997)
Appl. Microbiol. Biotechnol.
, vol.47
, pp. 373-378
-
-
Sriubolmas, N.1
Panbangred, W.2
Sriurairatana, S.3
Meevootisom, V.4
-
42
-
-
0034733816
-
Bacterial protein translocase: A unique molecular machine with an army of substrates
-
Economou, A.: Bacterial protein translocase: a unique molecular machine with an army of substrates. FEBS Lett., 476, 18-21 (2000).
-
(2000)
FEBS Lett.
, vol.476
, pp. 18-21
-
-
Economou, A.1
-
43
-
-
0033136533
-
Effect of SecB chaperone on production of periplasmic penicillin acylase in Escherichia coli
-
Chou, C. P., Tseng, J., Kuo, B., Lai, K., Lin, M., and Lin, H.: Effect of SecB chaperone on production of periplasmic penicillin acylase in Escherichia coli. Biotechnol. Prog., 15, 439-445 (1999).
-
(1999)
Biotechnol. Prog.
, vol.15
, pp. 439-445
-
-
Chou, C.P.1
Tseng, J.2
Kuo, B.3
Lai, K.4
Lin, M.5
Lin, H.6
-
44
-
-
0029829590
-
A common export pathway for proteins binding complex redox cofactors?
-
Berks, B. C.: A common export pathway for proteins binding complex redox cofactors? Mol. Microbiol., 22, 393-404 (1996).
-
(1996)
Mol. Microbiol.
, vol.22
, pp. 393-404
-
-
Berks, B.C.1
-
45
-
-
0036088769
-
Unusual signal peptide directs penicillin amidase from Escherichia coli to the Tat translocation machinery
-
Ignatova, Z., Hornle, C., Nurk, A., and Kasche, V.: Unusual signal peptide directs penicillin amidase from Escherichia coli to the Tat translocation machinery. Biochem. Biophys. Res. Commun., 291, 146-149 (2002).
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.291
, pp. 146-149
-
-
Ignatova, Z.1
Hornle, C.2
Nurk, A.3
Kasche, V.4
-
46
-
-
0037315336
-
Improvement of posttranslational bottlenecks in the production of penicillin amidase in recombinant Escherichia coli strains
-
Ignatova, Z., Mahsunah, A., Georgieya, M., and Kasche, V.: Improvement of posttranslational bottlenecks in the production of penicillin amidase in recombinant Escherichia coli strains. Appl. Environ. Microbiol., 69, 1237-1245 (2003).
-
(2003)
Appl. Environ. Microbiol.
, vol.69
, pp. 1237-1245
-
-
Ignatova, Z.1
Mahsunah, A.2
Georgieya, M.3
Kasche, V.4
-
47
-
-
0035919127
-
DegP-coexpression minimizes inclusion-body formation upon overproduction of recombinant penicillin acylase in Escherichia coli
-
Lin, W., Huang, S., and Chou, C. P.: DegP-coexpression minimizes inclusion-body formation upon overproduction of recombinant penicillin acylase in Escherichia coli. Biotechnol. Bioeng., 73, 484-492 (2001).
-
(2001)
Biotechnol. Bioeng.
, vol.73
, pp. 484-492
-
-
Lin, W.1
Huang, S.2
Chou, C.P.3
-
48
-
-
0038643369
-
Roles of DegP in prevention of protein misfolding in the periplasm upon overexpression of penicillin acylase in Escherichia coli
-
Pan, K. L., Hsiao, H. C., Weng, C. L., Wu, M. S., and Chou, C. P.: Roles of DegP in prevention of protein misfolding in the periplasm upon overexpression of penicillin acylase in Escherichia coli. J. Bacteriol., 185, 3020-3030 (2003).
-
(2003)
J. Bacteriol.
, vol.185
, pp. 3020-3030
-
-
Pan, K.L.1
Hsiao, H.C.2
Weng, C.L.3
Wu, M.S.4
Chou, C.P.5
-
49
-
-
0028036517
-
Periplasmic aggregation limits the proteolytic maturation of the Escherichia coli penicillin G amidase precursor polypeptide
-
Scherrer, S., Robas, N., Zouheiry, H., Branlant, G., and Branlant, C.: Periplasmic aggregation limits the proteolytic maturation of the Escherichia coli penicillin G amidase precursor polypeptide. Appl. Microbiol. Biotechnol., 42, 85-91 (1994).
-
(1994)
Appl. Microbiol. Biotechnol.
, vol.42
, pp. 85-91
-
-
Scherrer, S.1
Robas, N.2
Zouheiry, H.3
Branlant, G.4
Branlant, C.5
-
50
-
-
0034794414
-
High-level extracellular production of penicillin acylase by genetic engineering of Escherichia coli
-
Lin, W., Huang, S., and Chou, C. P.: High-level extracellular production of penicillin acylase by genetic engineering of Escherichia coli. J. Chem. Technol. Biotechnol., 76, 1030-1037 (2001).
-
(2001)
J. Chem. Technol. Biotechnol.
, vol.76
, pp. 1030-1037
-
-
Lin, W.1
Huang, S.2
Chou, C.P.3
-
51
-
-
0026601663
-
Proteases and protein degradation in Escherichia coli
-
Maurizi, M. R.: Proteases and protein degradation in Escherichia coli. Experentia, 48, 178-201 (1992).
-
(1992)
Experentia
, vol.48
, pp. 178-201
-
-
Maurizi, M.R.1
-
52
-
-
0034135677
-
The relative importance of intracellular proteolysis and transport on the yield of the periplasmic enzyme penicillin amidase in Escherichia coli
-
Ignatova, Z., Enfors, S., Hobbie, M., Taruttis, S., Vogt, C., and Kasche, V.: The relative importance of intracellular proteolysis and transport on the yield of the periplasmic enzyme penicillin amidase in Escherichia coli. Enzyme Microb. Technol., 26, 165-170 (2000).
-
(2000)
Enzyme Microb. Technol.
, vol.26
, pp. 165-170
-
-
Ignatova, Z.1
Enfors, S.2
Hobbie, M.3
Taruttis, S.4
Vogt, C.5
Kasche, V.6
-
53
-
-
0027908935
-
Improved penicillin amidase production using a genetically engineered mutant of Escherichia coli ATCC 11105
-
Robas, N., Zouheiry, H., Branlant, G., and Branlant, C.: Improved penicillin amidase production using a genetically engineered mutant of Escherichia coli ATCC 11105. Biotechnol. Bioeng., 41, 14-24 (1993).
-
(1993)
Biotechnol. Bioeng.
, vol.41
, pp. 14-24
-
-
Robas, N.1
Zouheiry, H.2
Branlant, G.3
Branlant, C.4
-
54
-
-
0008472227
-
Novel strategy for efficient screening and construction of host/vector systems to overproduce penicillin acylase in Escherichia coli
-
Chou, C. P., Yu, C., Lin, W., Kuo, B., and Wang, W.: Novel strategy for efficient screening and construction of host/vector systems to overproduce penicillin acylase in Escherichia coli. Biotechnol. Bioeng., 65, 219-226 (1999).
-
(1999)
Biotechnol. Bioeng.
, vol.65
, pp. 219-226
-
-
Chou, C.P.1
Yu, C.2
Lin, W.3
Kuo, B.4
Wang, W.5
-
55
-
-
0030269978
-
Development of a high-expression system for penicillin G acylase based on the recombinant Escherichia coli strain RE3 (pKA18)
-
Sobotkova, L., Stepanek, V., Plhackova, K., and Kyslik, P.: Development of a high-expression system for penicillin G acylase based on the recombinant Escherichia coli strain RE3 (pKA18). Enzyme Microb. Technol., 19, 389-397 (1996).
-
(1996)
Enzyme Microb. Technol.
, vol.19
, pp. 389-397
-
-
Sobotkova, L.1
Stepanek, V.2
Plhackova, K.3
Kyslik, P.4
-
56
-
-
0035667380
-
A biochemical engineering approach for enhancing production of recombinant penicillin acylase in Escherichia coli
-
Lin, W., Kuo, B., and Chou, C. P.: A biochemical engineering approach for enhancing production of recombinant penicillin acylase in Escherichia coli. Bioprocess Biosyst. Eng., 24, 239-247 (2001).
-
(2001)
Bioprocess Biosyst. Eng.
, vol.24
, pp. 239-247
-
-
Lin, W.1
Kuo, B.2
Chou, C.P.3
-
57
-
-
0027572338
-
Mechanism-based strategies for protein thermostabilization
-
Mozhaev, V. V.: Mechanism-based strategies for protein thermostabilization. Trends Biotechnol., 11, 88-95 (1993).
-
(1993)
Trends Biotechnol.
, vol.11
, pp. 88-95
-
-
Mozhaev, V.V.1
-
58
-
-
0028098166
-
The influence of polyalcohols and carbohydrates on the thermostability of α-amylase
-
De Cordt, S., Hendrickx, M., Maesmans, G., and Tobback, P.: The influence of polyalcohols and carbohydrates on the thermostability of α-amylase. Biotechnol. Bioeng., 43, 107-114 (1994).
-
(1994)
Biotechnol. Bioeng.
, vol.43
, pp. 107-114
-
-
De Cordt, S.1
Hendrickx, M.2
Maesmans, G.3
Tobback, P.4
-
59
-
-
0032714181
-
Stability and stabilization of penicillin acylase
-
Azevedo, A. M., Fonseca, L. P., and Prazeres, D. M. F.: Stability and stabilization of penicillin acylase. J. Chem. Technol. Biotechnol., 74, 1110-1116 (1999).
-
(1999)
J. Chem. Technol. Biotechnol.
, vol.74
, pp. 1110-1116
-
-
Azevedo, A.M.1
Fonseca, L.P.2
Prazeres, D.M.F.3
-
60
-
-
0033406289
-
Effect of dextran polymers on the stability of soluble Escherichia coli penicillin acylase
-
Kazan, D. and Erarslan, A.: Effect of dextran polymers on the stability of soluble Escherichia coli penicillin acylase. J. Chem. Technol. Biotechnol., 74, 1157-1164 (1999).
-
(1999)
J. Chem. Technol. Biotechnol.
, vol.74
, pp. 1157-1164
-
-
Kazan, D.1
Erarslan, A.2
-
61
-
-
0026700681
-
Thermal inactivation kinetics of penicillin G acylase obtained from a mutant derivative of Escherichia coli ATCC 11105
-
Erarslan, A. and Kocer, H.: Thermal inactivation kinetics of penicillin G acylase obtained from a mutant derivative of Escherichia coli ATCC 11105. J. Chem. Technol. Biotechnol., 55, 79-84 (1992).
-
(1992)
J. Chem. Technol. Biotechnol.
, vol.55
, pp. 79-84
-
-
Erarslan, A.1
Kocer, H.2
-
62
-
-
0029040546
-
Thermostabilization of penicillin G acylase obtained from a mutant of E. coli ATCC 11105 by bisimidoesters as homobifunctional cross-linking agents
-
Erarslan, A. and Ertan, H.: Thermostabilization of penicillin G acylase obtained from a mutant of E. coli ATCC 11105 by bisimidoesters as homobifunctional cross-linking agents. Enzyme Microb. Technol., 17, 629-635 (1995).
-
(1995)
Enzyme Microb. Technol.
, vol.17
, pp. 629-635
-
-
Erarslan, A.1
Ertan, H.2
-
63
-
-
0030773072
-
Stabilization of Escherichia coli penicillin G acylase against thermal inactivation by cross-linking with dextran dialdehyde polymers
-
Kazan, D., Ertan, H., and Erarslan, A.: Stabilization of Escherichia coli penicillin G acylase against thermal inactivation by cross-linking with dextran dialdehyde polymers. Appl. Microbiol. Biotechnol., 48, 191-197 (1997).
-
(1997)
Appl. Microbiol. Biotechnol.
, vol.48
, pp. 191-197
-
-
Kazan, D.1
Ertan, H.2
Erarslan, A.3
-
64
-
-
0036010287
-
High-level secretory expression of penicillin amidase from Providencia rettgeri in Saccharomyces cerevisiae: Purification and characterization
-
Ljubijankic, G., Gvozdenovic, J., Sevo, M., and Degrassi, G.: High-level secretory expression of penicillin amidase from Providencia rettgeri in Saccharomyces cerevisiae: purification and characterization. Biotechnol. Prog., 18, 330-336 (2002).
-
(2002)
Biotechnol. Prog.
, vol.18
, pp. 330-336
-
-
Ljubijankic, G.1
Gvozdenovic, J.2
Sevo, M.3
Degrassi, G.4
-
65
-
-
0036231497
-
Production of glycosylated thermostable Providencia rettgeri penicillin G amidase in Pichia pastoris
-
Sevo, M., Degrassi, G., Skoko, N., Venturi, V., and Ljubijankic, G.: Production of glycosylated thermostable Providencia rettgeri penicillin G amidase in Pichia pastoris. FEMS Yeast Res., 1, 271-277 (2002).
-
(2002)
FEMS Yeast Res.
, vol.1
, pp. 271-277
-
-
Sevo, M.1
Degrassi, G.2
Skoko, N.3
Venturi, V.4
Ljubijankic, G.5
-
66
-
-
0029176047
-
Stabilization of penicillin G acylase against pH by chemical crosslinking
-
Kazan, D., Ertan, H., and Erarslan, A.: Stabilization of penicillin G acylase against pH by chemical crosslinking. Process Biochem., 31, 135-140 (1996).
-
(1996)
Process Biochem.
, vol.31
, pp. 135-140
-
-
Kazan, D.1
Ertan, H.2
Erarslan, A.3
-
67
-
-
0030899458
-
Cross-linked stabilization of Escherichia coli penicillin G acylase against pH by dextran-dialdehyde polymers
-
Ertan, H., Kazan, D., and Erarslan, A.: Cross-linked stabilization of Escherichia coli penicillin G acylase against pH by dextran-dialdehyde polymers. Biotechnol. Tech., 11, 225-229 (1997).
-
(1997)
Biotechnol. Tech.
, vol.11
, pp. 225-229
-
-
Ertan, H.1
Kazan, D.2
Erarslan, A.3
-
68
-
-
0034769575
-
Stability enhancement of Escherichia coli penicillin G acylase by glycosylation with yeast mannan
-
Masarova, J., Mislovicova, D., Gemeiner, P., and Michalkova, E.: Stability enhancement of Escherichia coli penicillin G acylase by glycosylation with yeast mannan. Biotechnol. Appl. Biochem., 34, 127-133 (2001).
-
(2001)
Biotechnol. Appl. Biochem.
, vol.34
, pp. 127-133
-
-
Masarova, J.1
Mislovicova, D.2
Gemeiner, P.3
Michalkova, E.4
-
69
-
-
0036933779
-
Stabilization and functional properties of Escherichia coli penicillin G acylase by covalent conjugation of anionic polysaccharide carboxymethylcellulose
-
Ozturk, D. C., Kazan, D., and Erarslan, A.: Stabilization and functional properties of Escherichia coli penicillin G acylase by covalent conjugation of anionic polysaccharide carboxymethylcellulose. World J. Microbiol. Biotechnol., 18, 881-888 (2002).
-
(2002)
World J. Microbiol. Biotechnol.
, vol.18
, pp. 881-888
-
-
Ozturk, D.C.1
Kazan, D.2
Erarslan, A.3
-
70
-
-
0036750876
-
Enzyme reaction engineering: Effect of methanol on the synthesis of antibiotics catalyzed by immobilized penicillin G acylase under isothermal and non-isothermal conditions
-
Travascio, P., Zito, E., Portaccio, M., Diano, N., Grano, V., Di Martino, S., Bertolini, T., Rossi, S., and Mita, D. G.: Enzyme reaction engineering: effect of methanol on the synthesis of antibiotics catalyzed by immobilized penicillin G acylase under isothermal and non-isothermal conditions. Biotechnol. Prog., 18, 975-985 (2002).
-
(2002)
Biotechnol. Prog.
, vol.18
, pp. 975-985
-
-
Travascio, P.1
Zito, E.2
Portaccio, M.3
Diano, N.4
Grano, V.5
Di Martino, S.6
Bertolini, T.7
Rossi, S.8
Mita, D.G.9
-
71
-
-
0036219285
-
Optimization of yield in kinetically controlled synthesis of ampicillin with immobilized penicillin acylase in organic media
-
Illanes, A., Anjari, S., Arrieta, R., and Aguirre, C.: Optimization of yield in kinetically controlled synthesis of ampicillin with immobilized penicillin acylase in organic media. Appl. Biochem. Biotechnol., 97, 165-179 (2002).
-
(2002)
Appl. Biochem. Biotechnol.
, vol.97
, pp. 165-179
-
-
Illanes, A.1
Anjari, S.2
Arrieta, R.3
Aguirre, C.4
-
72
-
-
0035931395
-
Kinetically controlled synthesis of ampicillin with immobilized penicillin acylase in the presence of organic cosolvents
-
Illanes, A. and Fajardo, A.: Kinetically controlled synthesis of ampicillin with immobilized penicillin acylase in the presence of organic cosolvents. J. Mol. Catal. B: Enzym., 11, 587-595 (2001).
-
(2001)
J. Mol. Catal. B: Enzym.
, vol.11
, pp. 587-595
-
-
Illanes, A.1
Fajardo, A.2
-
73
-
-
0032890111
-
Facile synthesis of artificial enzyme nano-environments via solid-phase chemistry of immobilized derivatives: Dramatic stabilization of penicillin acylase versus organic solvents
-
Fernandez-Lafuente, R., Rosell, C. M., Caanan-Haden, L., Rodes, L., and Guisan, J. M.: Facile synthesis of artificial enzyme nano-environments via solid-phase chemistry of immobilized derivatives: dramatic stabilization of penicillin acylase versus organic solvents. Enzyme Microb. Technol., 24, 96-103 (1999).
-
(1999)
Enzyme Microb. Technol.
, vol.24
, pp. 96-103
-
-
Fernandez-Lafuente, R.1
Rosell, C.M.2
Caanan-Haden, L.3
Rodes, L.4
Guisan, J.M.5
-
74
-
-
0037008370
-
Penicillin amidase is activated for use in nonaqueous media by lyophilizing in the presence of potassium chloride
-
Lindsay, J. P., Clark, D. S., and Dordick, J. S.: Penicillin amidase is activated for use in nonaqueous media by lyophilizing in the presence of potassium chloride. Enzyme Microb. Technol., 31, 193-197 (2002).
-
(2002)
Enzyme Microb. Technol.
, vol.31
, pp. 193-197
-
-
Lindsay, J.P.1
Clark, D.S.2
Dordick, J.S.3
-
75
-
-
0036202029
-
Influence of external mass transfer limitation on apparent kinetic parameters of penicillin G acylase immobilized on nonporous ultrafine silica particles
-
Kheirolomoom, A., Khorasheh, F., and Fazelina., H.: Influence of external mass transfer limitation on apparent kinetic parameters of penicillin G acylase immobilized on nonporous ultrafine silica particles. J. Biosci. Bioeng., 93, 125-129 (2002).
-
(2002)
J. Biosci. Bioeng.
, vol.93
, pp. 125-129
-
-
Kheirolomoom, A.1
Khorasheh, F.2
Fazelina, H.3
-
76
-
-
0034234028
-
Advances in enzymatic transformation of penicillins to 6-aminopenicillanic acid (6-APA)
-
Parmar, A., Kumar, H., Marwaha, S. S., and Kennedy, J. F.: Advances in enzymatic transformation of penicillins to 6-aminopenicillanic acid (6-APA). Biotechnol. Adv., 18, 289-301 (2000).
-
(2000)
Biotechnol. Adv.
, vol.18
, pp. 289-301
-
-
Parmar, A.1
Kumar, H.2
Marwaha, S.S.3
Kennedy, J.F.4
-
77
-
-
0026816478
-
Immobilization of permeabilized Escherichia coli cells with penicillin acylase activity
-
Prabhune, A. A., Rao, B. S., Pundle, A. V., and Sivaraman, H.: Immobilization of permeabilized Escherichia coli cells with penicillin acylase activity. Enzyme Microb. Technol., 14, 161-163 (1992).
-
(1992)
Enzyme Microb. Technol.
, vol.14
, pp. 161-163
-
-
Prabhune, A.A.1
Rao, B.S.2
Pundle, A.V.3
Sivaraman, H.4
-
78
-
-
0037039499
-
Immobilization of whole cell penicillin G acylase in open pore gelatin matrix
-
Norouzian, D., Javadpoura, S., Moazamib, N., and Akbarzadeba, A.: Immobilization of whole cell penicillin G acylase in open pore gelatin matrix. Enzyme Microb. Technol., 30, 26-29 (2002).
-
(2002)
Enzyme Microb. Technol.
, vol.30
, pp. 26-29
-
-
Norouzian, D.1
Javadpoura, S.2
Moazamib, N.3
Akbarzadeba, A.4
-
79
-
-
0033179495
-
Crosslinking of enzymes for improved stability and performance
-
Govardhan, C.: Crosslinking of enzymes for improved stability and performance. Curr. Opin. Biotechnol., 10, 331-335 (1999).
-
(1999)
Curr. Opin. Biotechnol.
, vol.10
, pp. 331-335
-
-
Govardhan, C.1
-
80
-
-
0035931490
-
Cross-linked aggregates of penicillin acylase: Robust catalysts for the synthesis of β-lactam antibiotics
-
Cao, L., Langen, L. M., Rantwijk, F., and Sheldon, R. A.: Cross-linked aggregates of penicillin acylase: robust catalysts for the synthesis of β-lactam antibiotics. J. Mol. Catal. B: Enzym., 11, 665-670 (2001).
-
(2001)
J. Mol. Catal. B: Enzym.
, vol.11
, pp. 665-670
-
-
Cao, L.1
Langen, L.M.2
Rantwijk, F.3
Sheldon, R.A.4
-
81
-
-
0030877138
-
Protein engineering from a bioindustrial point of view
-
Rubingh, D. N.: Protein engineering from a bioindustrial point of view. Curr. Opin. Biotechnol., 8, 417-422 (1997).
-
(1997)
Curr. Opin. Biotechnol.
, vol.8
, pp. 417-422
-
-
Rubingh, D.N.1
-
82
-
-
0025596961
-
Evidence for involvement of an arginyl residue at the catalytic site of penicillin acylase from Escherichia coli
-
Prabhune, A. A. and Sivaraman, H.: Evidence for involvement of an arginyl residue at the catalytic site of penicillin acylase from Escherichia coli. Biochem. Biophys. Res. Commun., 173, 317-322 (1990).
-
(1990)
Biochem. Biophys. Res. Commun.
, vol.173
, pp. 317-322
-
-
Prabhune, A.A.1
Sivaraman, H.2
-
83
-
-
0035066330
-
Identification of catalytically essential amino acid residues of penicillin G acylase obtained from a mutant of Escherichia coli ATCC 11105
-
Kazan, D. and Erarslan, A.: Identification of catalytically essential amino acid residues of penicillin G acylase obtained from a mutant of Escherichia coli ATCC 11105. Process Biochem., 36, 861-867 (2001).
-
(2001)
Process Biochem.
, vol.36
, pp. 861-867
-
-
Kazan, D.1
Erarslan, A.2
-
84
-
-
0023056887
-
Penicillin acylase from E. coli: Unique gene-protein relation
-
Schumacber, G., Sizmann, D., Haug, H., Buckel, P., and Bock, A.: Penicillin acylase from E. coli: unique gene-protein relation. Nucleic Acids Res., 14, 5713-5727 (1986).
-
(1986)
Nucleic Acids Res.
, vol.14
, pp. 5713-5727
-
-
Schumacber, G.1
Sizmann, D.2
Haug, H.3
Buckel, P.4
Bock, A.5
-
85
-
-
0025100583
-
Primary structure requirements for the maturation in vivo of penicillin acylase from Escherichia coli ATCC 11105
-
Sizmann, D., Keilmann, C., and Bock, A.: Primary structure requirements for the maturation in vivo of penicillin acylase from Escherichia coli ATCC 11105. Eur. J. Biochem., 192, 143-151 (1990).
-
(1990)
Eur. J. Biochem.
, vol.192
, pp. 143-151
-
-
Sizmann, D.1
Keilmann, C.2
Bock, A.3
-
86
-
-
0032795578
-
Intramolecular autoproteolysis initiates the maturation of penicillin amidase from Escherichia coli
-
Kasche, V., Lummer, K., Nurk, A., Piotraschke, E., Rieks, A., Stoeva, S., and Voelter, W.: Intramolecular autoproteolysis initiates the maturation of penicillin amidase from Escherichia coli. Biochim. Biophys. Acta, 1433, 76-86 (1999).
-
(1999)
Biochim. Biophys. Acta
, vol.1433
, pp. 76-86
-
-
Kasche, V.1
Lummer, K.2
Nurk, A.3
Piotraschke, E.4
Rieks, A.5
Stoeva, S.6
Voelter, W.7
-
87
-
-
0034462589
-
Characterization of the β-lactam binding site of penicillin acylase of Escherichia coli by structural and site-directed mutagenesis studies
-
Alkema, W. B. L., Hensgens, C. M. H., Kroezinga, E. H., De Vries, E., Floris, R., Laan, V. J. M., Dijkstra, B. W., and Janssen, D. B.: Characterization of the β-lactam binding site of penicillin acylase of Escherichia coli by structural and site-directed mutagenesis studies. Protein Eng., 13, 857-863 (2000).
-
(2000)
Protein Eng.
, vol.13
, pp. 857-863
-
-
Alkema, W.B.L.1
Hensgens, C.M.H.2
Kroezinga, E.H.3
De Vries, E.4
Floris, R.5
Laan, V.J.M.6
Dijkstra, B.W.7
Janssen, D.B.8
-
88
-
-
0036237518
-
The role of hydrophobic active-site residues in substrate specificity and acyl transfer activity of penicillin acylase
-
Alkema, W. B. L., Dijkhuis, A., De Vries, E., and Janssen, D. B.: The role of hydrophobic active-site residues in substrate specificity and acyl transfer activity of penicillin acylase. Eur. J. Biochem., 269, 2093-2100 (2002).
-
(2002)
Eur. J. Biochem.
, vol.269
, pp. 2093-2100
-
-
Alkema, W.B.L.1
Dijkhuis, A.2
De Vries, E.3
Janssen, D.B.4
-
89
-
-
0036628544
-
Role of αArg145 and βArg263 in the active site of penicillin acylase of Escherichia coli
-
Alkema, W. B. L., Prins, A. K., De Vries, E., and Janssen, D. B.: Role of αArg145 and βArg263 in the active site of penicillin acylase of Escherichia coli. Biochem. J., 365, 303-309 (2002).
-
(2002)
Biochem. J.
, vol.365
, pp. 303-309
-
-
Alkema, W.B.L.1
Prins, A.K.2
De Vries, E.3
Janssen, D.B.4
-
90
-
-
0037164179
-
Rational design of a more stable penicillin G acylase against organic cosolvent
-
Yang, S., Zhou, L., Tang, H., Pan, J., Wu, X., Huang, H., and Yuan, Z.: Rational design of a more stable penicillin G acylase against organic cosolvent. J. Mol. Catal. B: Enzym., 18, 285-290 (2002).
-
(2002)
J. Mol. Catal. B: Enzym.
, vol.18
, pp. 285-290
-
-
Yang, S.1
Zhou, L.2
Tang, H.3
Pan, J.4
Wu, X.5
Huang, H.6
Yuan, Z.7
-
91
-
-
0031543435
-
Directed evolution of enzyme catalysts
-
Kuchner, O. and Arnold, F. H.: Directed evolution of enzyme catalysts. Trends Biotechnol., 15, 523-530 (1997).
-
(1997)
Trends Biotechnol.
, vol.15
, pp. 523-530
-
-
Kuchner, O.1
Arnold, F.H.2
-
92
-
-
0024440475
-
Selection of amidases with novel substrate specificities from penicillin amidase of Escherichia coli
-
Forney, L. J., Wong, D. C., and Ferber, D. M.: Selection of amidases with novel substrate specificities from penicillin amidase of Escherichia coli. Appl. Environ. Microbiol., 55, 2550-2555 (1989).
-
(1989)
Appl. Environ. Microbiol.
, vol.55
, pp. 2550-2555
-
-
Forney, L.J.1
Wong, D.C.2
Ferber, D.M.3
-
93
-
-
0024425139
-
Alteration of the catalytic efficiency of penicillin amidase from Escherichia coli
-
Forney, L. J. and Wong, D. C.: Alteration of the catalytic efficiency of penicillin amidase from Escherichia coli. Appl. Environ. Microbiol., 55, 2556-2560 (1989).
-
(1989)
Appl. Environ. Microbiol.
, vol.55
, pp. 2556-2560
-
-
Forney, L.J.1
Wong, D.C.2
-
94
-
-
0028172065
-
Changing the substrate specificity of penicillin G acylase from Kluyvera citrophila through selective pressure
-
Rao, A., Garcia, J. L., Salto, F., and Cortes, E.: Changing the substrate specificity of penicillin G acylase from Kluyvera citrophila through selective pressure. Biochem. J., 303, 869-875 (1994).
-
(1994)
Biochem. J.
, vol.303
, pp. 869-875
-
-
Rao, A.1
Garcia, J.L.2
Salto, F.3
Cortes, E.4
-
95
-
-
0028923978
-
Isolation and mapping of a mutant penicillin G acylase with altered substrate specificity from Escherichia coli
-
Niersbach, H., Tischer, W., Weber, M., Wedekind, F., and Plapp, R.: Isolation and mapping of a mutant penicillin G acylase with altered substrate specificity from Escherichia coli. Biotechnol. Lett., 17, 19-24 (1995).
-
(1995)
Biotechnol. Lett.
, vol.17
, pp. 19-24
-
-
Niersbach, H.1
Tischer, W.2
Weber, M.3
Wedekind, F.4
Plapp, R.5
-
96
-
-
0029091933
-
Improvement of the catalytic properties of penicillin G acylase from Escherichia coli ATCC 11105 by selection of a new substrate specificity
-
Niersbach, H., Kuhne, A., Tischer, W., Weber, M., Wedekind, F., and Plapp, R.: Improvement of the catalytic properties of penicillin G acylase from Escherichia coli ATCC 11105 by selection of a new substrate specificity. Appl. Microbiol. Biotechnol., 43, 679-684 (1995).
-
(1995)
Appl. Microbiol. Biotechnol.
, vol.43
, pp. 679-684
-
-
Niersbach, H.1
Kuhne, A.2
Tischer, W.3
Weber, M.4
Wedekind, F.5
Plapp, R.6
-
97
-
-
0033199842
-
Processing and functional display of the 86 kDa heterodimeric penicillin G acylase on the surface of phage fd
-
Verhaert, R. M. D., Duina, J. V., and Quax, W. J.: Processing and functional display of the 86 kDa heterodimeric penicillin G acylase on the surface of phage fd. Biochem. J., 342, 415-422 (1999).
-
(1999)
Biochem. J.
, vol.342
, pp. 415-422
-
-
Verhaert, R.M.D.1
Duina, J.V.2
Quax, W.J.3
-
98
-
-
0028050350
-
Rapid evolution of a protein in vitro by DNA shuffling
-
Stemmer, W. P.: Rapid evolution of a protein in vitro by DNA shuffling. Nature, 370, 389-391 (1994).
-
(1994)
Nature
, vol.370
, pp. 389-391
-
-
Stemmer, W.P.1
-
99
-
-
0032518266
-
DNA shuffling of a family of genes from diverse species accelerates directed evolution
-
Crameri, A., Raillard, S. A., Bermudez, E., and Stemmer, W. P.: DNA shuffling of a family of genes from diverse species accelerates directed evolution. Nature, 391, 288-291 (1998).
-
(1998)
Nature
, vol.391
, pp. 288-291
-
-
Crameri, A.1
Raillard, S.A.2
Bermudez, E.3
Stemmer, W.P.4
-
100
-
-
0041384171
-
Improving the specific synthetic activity of a penicillin G acylase using DNA family shuffling
-
Zheng, Z., Ai-Hui, Z., Jing-Ru, W., Mao-Lin, C., RenBao, L., Sheng, Y., and Zhong-Yi, Y.: Improving the specific synthetic activity of a penicillin G acylase using DNA family shuffling. Acta Biochim. Biophys. Sin., 35, 573-579 (2003).
-
(2003)
Acta Biochim. Biophys. Sin.
, vol.35
, pp. 573-579
-
-
Zheng, Z.1
Ai-Hui, Z.2
Jing-Ru, W.3
Mao-Lin, C.4
Renbao, L.5
Sheng, Y.6
Zhong-Yi, Y.7
-
101
-
-
0026697771
-
Effects of site-directed mutations on processing and activities of penicillin G acylase from Escherichia coli ATCC 11105
-
Choi, K. S., Kim, J. A., and Kang, H. S.: Effects of site-directed mutations on processing and activities of penicillin G acylase from Escherichia coli ATCC 11105. J. Bacteriol., 174, 6270-6276 (1992).
-
(1992)
J. Bacteriol.
, vol.174
, pp. 6270-6276
-
-
Choi, K.S.1
Kim, J.A.2
Kang, H.S.3
-
102
-
-
0034720448
-
Identification of a new active site for autocatalytic processing of penicillin acylase precursor in Escherichia coli ATCC 11105
-
Lee, H., Park, O. K., and Kang, H. S.: Identification of a new active site for autocatalytic processing of penicillin acylase precursor in Escherichia coli ATCC 11105. Biochem. Biophys. Res. Commun., 272, 199-204 (2000).
-
(2000)
Biochem. Biophys. Res. Commun.
, vol.272
, pp. 199-204
-
-
Lee, H.1
Park, O.K.2
Kang, H.S.3
-
103
-
-
0035850792
-
Crystal structure of penicillin acylase enzyme-substrate complexes: Structural insights into the catalytic mechanism
-
McVey, C. E., Walsh, M. A., Dodson, G. G., Wilson, K. S., and Brannigan, J. A.: Crystal structure of penicillin acylase enzyme-substrate complexes: structural insights into the catalytic mechanism. J. Mol. Biol., 313, 139-150 (2001).
-
(2001)
J. Mol. Biol.
, vol.313
, pp. 139-150
-
-
McVey, C.E.1
Walsh, M.A.2
Dodson, G.G.3
Wilson, K.S.4
Brannigan, J.A.5
-
105
-
-
0025160413
-
Penicillin acylase mutants with altered site-directed activity from Kluyvera citrophila
-
Prieto, I., Martin, J., Arche, R., Fernandez, P., Perez-Aranda, A., and Barbero, J. L.: Penicillin acylase mutants with altered site-directed activity from Kluyvera citrophila. Appl. Microbiol. Biotechnol., 33, 553-559 (1990).
-
(1990)
Appl. Microbiol. Biotechnol.
, vol.33
, pp. 553-559
-
-
Prieto, I.1
Martin, J.2
Arche, R.3
Fernandez, P.4
Perez-Aranda, A.5
Barbero, J.L.6
-
106
-
-
0026598688
-
Changing glycine 21 for glutamic acid in the β-subunit of penicillin G acylase from Kluyvera citrophila prevents protein maturation
-
Prieto, I., Rodriguez, M. C., Marquez, G., Perez-Aranda, A., and Barbero, J. L.: Changing glycine 21 for glutamic acid in the β-subunit of penicillin G acylase from Kluyvera citrophila prevents protein maturation. Appl. Microbiol. Biotechnol., 36, 659-662 (1992).
-
(1992)
Appl. Microbiol. Biotechnol.
, vol.36
, pp. 659-662
-
-
Prieto, I.1
Rodriguez, M.C.2
Marquez, G.3
Perez-Aranda, A.4
Barbero, J.L.5
-
107
-
-
0026334245
-
Chemical modification of serine at the active site of penicillin acylase from Kluyvera citrophila
-
Martin, J., Slade, A., Aitken, A., Arche, R., and Virden, R.: Chemical modification of serine at the active site of penicillin acylase from Kluyvera citrophila. Biochem. J., 280, 659-662 (1991).
-
(1991)
Biochem. J.
, vol.280
, pp. 659-662
-
-
Martin, J.1
Slade, A.2
Aitken, A.3
Arche, R.4
Virden, R.5
-
108
-
-
0032884396
-
Crystal structure of penicillin G acylase from the Bro1 mutant strain of Providencia rettgeri
-
McDonough, M. A., Klei, H. E., and Kelly, J. A.: Crystal structure of penicillin G acylase from the Bro1 mutant strain of Providencia rettgeri. Protein Sci., 8, 1971-1981 (1999).
-
(1999)
Protein Sci.
, vol.8
, pp. 1971-1981
-
-
McDonough, M.A.1
Klei, H.E.2
Kelly, J.A.3
|