The practical application of aqueous two-phase processes for the recovery of biological products

Journal of Microbiology and Biotechnology

Volumn 12, Issue 4, 2002, Pages 535-543

  Rito Palomares, Marco ^a  

^a SCHOOL OF ENGINEERING AND SCIENCES   (Mexico)

Author keywords

ATPS processes; Process integration; Proteins; Recovery of biological products

Indexed keywords

BIOLOGICAL PRODUCT; POLYMER;

AQUEOUS SOLUTION; ARTICLE; BIOTECHNOLOGICAL PROCEDURES; CHEMICAL PROCEDURES; CONTROLLED STUDY; MEDICAL RESEARCH; MEDICAL TECHNOLOGY; PHASE PARTITIONING; PROCESS DESIGN; PRODUCT RECOVERY; PURIFICATION;

EID: 0036694420     PISSN: 10177825     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (51)

1. On protein partition in two-phase aqueous polymer systems
2. Cutinase purification on poly(ethyleneglycol)-hydroxypropyl starch aqueous two-phase systems
3. Partitioning of whey proteins, bovine serum albumin and porcine insulin in aqueous two-phase systems
4. Partitioning and purification of monoclonal antibodies in aqueous two-phase systems
5. Direct process integration of cell disruption and fluidised bed absorption for the recovery of intracellular proteins
6. Extraction in aqueous two-phase systems of alkaline xylanase produced by Bacillus pumpilus and its application in kraft pulp bleaching
7. Recovery in aqueous two-phase systems of nanoparticulates applied as surrogate mimics for viral gene therapy vectors
8. Theory of phase formation in aqueous two-phase systems
9. Technical aspects of extractive purification of penicillin fermentation broth by aqueous two-phase partitioning
10. The application of aqueous two-phase systems to the purification of pharmaceutical proteins from transgenic sheep milk
11. Large-scale in situ isolation of periplasmic IGF-I from Escherichia coli
12. Use of aqueous two-phase systems for in situ extraction of water soluble antibiotics during their synthesis by enzymes immobilized on porous supports
13. Separation and recovery of food coloring dyes using aqueous biphasic extraction chromatographic resin
14. The molecular basis of partitioning in aqueous two-phase systems
15. Applications of phase partition in biotechnology
16. Concentration and purification of β-glucosidase from Aspergillus niger by using aqueous two-phase partitioning
17. Driving forces for phase separation and partitioning in aqueous two-phase systems
18. Thermoseparating water/polymer system: A novel one-polymer aqueous two-phase system for protein purification
19. Extractive cultivation of recombinant Escherichia coli using aqueous two phase systems for product and separation of extracellular xylanase
20. Use of aqueous two-phase systems in sample preparation for polymerase chain reaction-based detection of microorganisms
21. 2O aqueous two-phase systems to produce nisin
22. Ucon-benzoyl dextran aqueous two-phase systems: Protein purification with phase component recycling
23. Variation of penicillin acylase partition coefficient with phase volume ratio in poly(ethylene glycol)-sodium citrate aqueous two-phase systems
24. Aqueous two-phase systems for protein separation studies on phase inversion
25. Separation and purification of glucoamylase in aqueous two-phase systems by two-step extraction
26. Milano expressed in Escherichia coli using aqueous two-phase extraction followed by temperature-induced phase separation
27. Purification of recombinant proteins using thermoseparating aqueous two-phase system and polymer recycling
28. New polymers forming aqueous two-phase systems
29. Novel polymer-polymer conjugates for recovery of lactic acid by aqueous two-phase extraction
30. Amine-based aqueous polymers for the simultaneous titration and extraction of lactic acid in aqueous two-phase systems
31. Aqueous two-phase systems containing urea: Influence on phase separation and stabilization of protein conformation by phase component
32. Effect of biological suspensions on the position of the binodal curve in aqueous two-phase systems
33. Influence of systems and process parameters on partitioning of cheese whey proteins in aqueous two-phase systems
34. Practical implementation of aqueous two-phase processes for protein recovery from yeast
35. Generic application of an aqueous two-phase process for protein recovery from animal blood
36. Aroma compounds recovery from mycelial cultures in aqueous two-phase processes
37. Metal ion separation in polyethylene glycol-based aqueous biphasic systems: Correlation of partitioning behaviour with available thermodynamic hydration data
38. Partitioning of small organic molecules in aqueous biphasic systems
39. New aqueous two-phase systems based on cashew-nut tree gum and poly(ethylene glycol)
40. On the kinetics of phase separation in aqueous two-phase systems
41. Extractive fermentation for improved production of endoglucanase by an intergeneric fusant of Trichoderma ressei/Saccharomyces cerevisiae using aqueous two-phase systems
42. Aqueous two-phase: The system of choice for extractive fermentation
43. Affinity partitioning of a poly(histidine)-tagged integral membrane protein, cytochrome bo3 ubiquinol oxidase, in a detergent-polymer aqueous two-phase system containing metal-chelating polymer
44. Kinetics of phase separation under different process and design parameters in aqueous two-phase systems
45. Drowning-out crystallisation of sodium sulphate using aqueous two-phase systems
46. Enzyme purification with aqueous two-phase systems: Comparison between systems composed of pure polymers and systems composed of crude polymers
47. Aqueous two-phase partition of complex protein feedstock derived from brain tissue homogenates
48. Aqueous two-phase systems as an alternative process route for the fractionation of small inclusion bodies
49. Extractive bioconversion in aqueous two-phase systems
50. IgG and hybridoma partitioning in aqueous two-phase systems containing a dye-ligand