-
1
-
-
0029150110
-
Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
-
S. Sakaguchi, N. Sakaguchi, M. Asano, M. Itoh, and M. Toda Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases J Immunol 155 1995 1151 1164
-
(1995)
J Immunol
, vol.155
, pp. 1151-1164
-
-
Sakaguchi, S.1
Sakaguchi, N.2
Asano, M.3
Itoh, M.4
Toda, M.5
-
2
-
-
2942642383
-
In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes
-
Q. Tang, K.J. Henriksen, M. Bi, E.B. Finger, G. Szot, and J. Ye In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes J Exp Med 199 2004 1455 1465
-
(2004)
J Exp Med
, vol.199
, pp. 1455-1465
-
-
Tang, Q.1
Henriksen, K.J.2
Bi, M.3
Finger, E.B.4
Szot, G.5
Ye, J.6
-
4
-
-
0036838536
-
+ regulatory T cells suppress antigen-specific autoreactive immune responses and central nervous system inflammation during active experimental autoimmune encephalomyelitis
-
+ regulatory T cells suppress antigen-specific autoreactive immune responses and central nervous system inflammation during active experimental autoimmune encephalomyelitis J Immunol 169 2002 4712 4716
-
(2002)
J Immunol
, vol.169
, pp. 4712-4716
-
-
Kohm, A.P.1
Carpentier, P.A.2
Anger, H.A.3
Miller, S.D.4
-
5
-
-
33746214867
-
Suppression of disease in New Zealand Black/New Zealand White lupus-prone mice by adoptive transfer of ex vivo expanded regulatory T cells
-
K.J. Scalapino, Q. Tang, J.A. Bluestone, M.L. Bonyhadi, and D.I. Daikh Suppression of disease in New Zealand Black/New Zealand White lupus-prone mice by adoptive transfer of ex vivo expanded regulatory T cells J Immunol 177 2006 1451 1459
-
(2006)
J Immunol
, vol.177
, pp. 1451-1459
-
-
Scalapino, K.J.1
Tang, Q.2
Bluestone, J.A.3
Bonyhadi, M.L.4
Daikh, D.I.5
-
6
-
-
0028873470
-
CTLA-4 gene polymorphism associated with Graves' disease in a Caucasian population
-
T. Yanagawa, Y. Hidaka, V. Guimaraes, M. Soliman, and L.J. DeGroot CTLA-4 gene polymorphism associated with Graves' disease in a Caucasian population J Clin Endocrinol Metab 80 1995 41 45
-
(1995)
J Clin Endocrinol Metab
, vol.80
, pp. 41-45
-
-
Yanagawa, T.1
Hidaka, Y.2
Guimaraes, V.3
Soliman, M.4
Degroot, L.J.5
-
7
-
-
22544445236
-
Association of CTLA4 polymorphism with regulatory T cell frequency
-
S.F. Atabani, C.L. Thio, S. Divanovic, A. Trompette, Y. Belkaid, and D.L. Thomas Association of CTLA4 polymorphism with regulatory T cell frequency Eur J Immunol 35 2005 2157 2162
-
(2005)
Eur J Immunol
, vol.35
, pp. 2157-2162
-
-
Atabani, S.F.1
Thio, C.L.2
Divanovic, S.3
Trompette, A.4
Belkaid, Y.5
Thomas, D.L.6
-
8
-
-
8944259914
-
The CTLA-4 gene region of chromosome 2q33 is linked to, and associated with, type 1 diabetes. Belgian Diabetes Registry
-
L. Nistico, R. Buzzetti, L.E. Pritchard, B. Van der Auwera, C. Giovannini, and E. Bosi The CTLA-4 gene region of chromosome 2q33 is linked to, and associated with, type 1 diabetes. Belgian Diabetes Registry Hum Mol Genet 5 1996 1075 1080
-
(1996)
Hum Mol Genet
, vol.5
, pp. 1075-1080
-
-
Nistico, L.1
Buzzetti, R.2
Pritchard, L.E.3
Van Der Auwera, B.4
Giovannini, C.5
Bosi, E.6
-
9
-
-
20244373351
-
Localization of a type 1 diabetes locus in the IL2RA/CD25 region by use of tag single-nucleotide polymorphisms
-
A. Vella, J.D. Cooper, C.E. Lowe, N. Walker, S. Nutland, and B. Widmer Localization of a type 1 diabetes locus in the IL2RA/CD25 region by use of tag single-nucleotide polymorphisms Am J Hum Genet 76 2005 773 779
-
(2005)
Am J Hum Genet
, vol.76
, pp. 773-779
-
-
Vella, A.1
Cooper, J.D.2
Lowe, C.E.3
Walker, N.4
Nutland, S.5
Widmer, B.6
-
10
-
-
0035167967
-
The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3
-
C.L. Bennett, J. Christie, F. Ramsdell, M.E. Brunkow, P.J. Ferguson, and L. Whitesell The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3 Nat Genet 27 2001 20 21
-
(2001)
Nat Genet
, vol.27
, pp. 20-21
-
-
Bennett, C.L.1
Christie, J.2
Ramsdell, F.3
Brunkow, M.E.4
Ferguson, P.J.5
Whitesell, L.6
-
11
-
-
0034526617
-
JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome
-
T.A. Chatila, F. Blaeser, N. Ho, H.M. Lederman, C. Voulgaropoulos, and C. Helms JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome J Clin Invest 106 2000 R75 R81
-
(2000)
J Clin Invest
, vol.106
-
-
Chatila, T.A.1
Blaeser, F.2
Ho, N.3
Lederman, H.M.4
Voulgaropoulos, C.5
Helms, C.6
-
12
-
-
0035163909
-
X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy
-
R.S. Wildin, F. Ramsdell, J. Peake, F. Faravelli, J.L. Casanova, and N. Buist X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy Nat Genet 27 2001 18 20
-
(2001)
Nat Genet
, vol.27
, pp. 18-20
-
-
Wildin, R.S.1
Ramsdell, F.2
Peake, J.3
Faravelli, F.4
Casanova, J.L.5
Buist, N.6
-
13
-
-
0035162560
-
Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse
-
M.E. Brunkow, E.W. Jeffery, K.A. Hjerrild, B. Paeper, and L.B. Clark Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse Nat Genet 27 2001 68 73
-
(2001)
Nat Genet
, vol.27
, pp. 68-73
-
-
Brunkow, M.E.1
Jeffery, E.W.2
Hjerrild, K.A.3
Paeper, B.4
Clark, L.B.5
-
14
-
-
25844504653
-
Developmental regulation of Foxp3 expression during ontogeny
-
J.D. Fontenot, J.L. Dooley, A.G. Farr, and A.Y. Rudensky Developmental regulation of Foxp3 expression during ontogeny J Exp Med 202 2005 901 906
-
(2005)
J Exp Med
, vol.202
, pp. 901-906
-
-
Fontenot, J.D.1
Dooley, J.L.2
Farr, A.G.3
Rudensky, A.Y.4
-
15
-
-
0347785480
-
Control of regulatory T cell development by the transcription factor Foxp3
-
S. Hori, T. Nomura, and S. Sakaguchi Control of regulatory T cell development by the transcription factor Foxp3 Science 299 2003 1057 1061
-
(2003)
Science
, vol.299
, pp. 1057-1061
-
-
Hori, S.1
Nomura, T.2
Sakaguchi, S.3
-
18
-
-
15244354286
-
Regulatory T cell lineage specification by the forkhead transcription factor foxp3
-
J.D. Fontenot Regulatory T cell lineage specification by the forkhead transcription factor foxp3 Immunity 22 2005 329 341
-
(2005)
Immunity
, vol.22
, pp. 329-341
-
-
Fontenot, J.D.1
-
21
-
-
0033682056
-
+ immunoregulatory T cells that control autoimmune diabetes
-
+ immunoregulatory T cells that control autoimmune diabetes Immunity 12 2000 431 440
-
(2000)
Immunity
, vol.12
, pp. 431-440
-
-
Salomon, B.1
-
22
-
-
13944260538
-
CD28 costimulation of developing thymocytes induces Foxp3 expression and regulatory T cell differentiation independently of interleukin 2
-
X. Tai, M. Cowan, L. Feigenbaum, and A. Singer CD28 costimulation of developing thymocytes induces Foxp3 expression and regulatory T cell differentiation independently of interleukin 2 Nat Immunol 6 2005 152 162
-
(2005)
Nat Immunol
, vol.6
, pp. 152-162
-
-
Tai, X.1
Cowan, M.2
Feigenbaum, L.3
Singer, A.4
-
23
-
-
0035920510
-
Major histocompatibility complex class II-positive cortical epithelium mediates the selection of CD4(+)25(+) immunoregulatory T cells
-
S.J. Bensinger, A. Bandeira, M.S. Jordan, A.J. Caton, and T.M. Laufer Major histocompatibility complex class II-positive cortical epithelium mediates the selection of CD4(+)25(+) immunoregulatory T cells J Exp Med 194 2001 427 438
-
(2001)
J Exp Med
, vol.194
, pp. 427-438
-
-
Bensinger, S.J.1
Bandeira, A.2
Jordan, M.S.3
Caton, A.J.4
Laufer, T.M.5
-
24
-
-
50149099154
-
Differentiation of regulatory Foxp3+ T cells in the thymic cortex
-
A. Liston, K.M. Nutsch, A.G. Farr, J.M. Lund, J.P. Rasmussen, and P.A. Koni Differentiation of regulatory Foxp3+ T cells in the thymic cortex Proc Natl Acad Sci USA 105 2008 11903 11908
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 11903-11908
-
-
Liston, A.1
Nutsch, K.M.2
Farr, A.G.3
Lund, J.M.4
Rasmussen, J.P.5
Koni, P.A.6
-
26
-
-
14544296063
-
CD4(+) CD25(+) regulatory T cell selection
-
A.J. Caton, C. Cozzo, J. Larkin 3rd, M.A. Lerman, A. Boesteanu, and M.S. Jordan CD4(+) CD25(+) regulatory T cell selection Ann NY Acad Sci 1029 2004 101 114
-
(2004)
Ann NY Acad Sci
, vol.1029
, pp. 101-114
-
-
Caton, A.J.1
Cozzo, C.2
Larkin III, J.3
Lerman, M.A.4
Boesteanu, A.5
Jordan, M.S.6
-
28
-
-
0036568942
-
Generation of CD4(+)CD25(+) regulatory T cells from autoreactive T cells simultaneously with their negative selection in the thymus and from nonautoreactive T cells by endogenous TCR expression
-
K. Kawahata, Y. Misaki, M. Yamauchi, S. Tsunekawa, K. Setoguchi, and J. Miyazaki Generation of CD4(+)CD25(+) regulatory T cells from autoreactive T cells simultaneously with their negative selection in the thymus and from nonautoreactive T cells by endogenous TCR expression J Immunol 168 2002 4399 4405
-
(2002)
J Immunol
, vol.168
, pp. 4399-4405
-
-
Kawahata, K.1
Misaki, Y.2
Yamauchi, M.3
Tsunekawa, S.4
Setoguchi, K.5
Miyazaki, J.6
-
30
-
-
9244244736
-
Number of T reg cells that differentiate does not increase upon encounter of agonist ligand on thymic epithelial cells
-
H.M. van Santen, C. Benoist, and D. Mathis Number of T reg cells that differentiate does not increase upon encounter of agonist ligand on thymic epithelial cells J Exp Med 200 2004 1221 1230
-
(2004)
J Exp Med
, vol.200
, pp. 1221-1230
-
-
Van Santen, H.M.1
Benoist, C.2
Mathis, D.3
-
31
-
-
37849009964
-
A two-step process for thymic regulatory T cell development
-
C.W. Lio, and C.S. Hsieh A two-step process for thymic regulatory T cell development Immunity 28 2008 100 111
-
(2008)
Immunity
, vol.28
, pp. 100-111
-
-
Lio, C.W.1
Hsieh, C.S.2
-
33
-
-
0036669298
-
CD4 regulatory T cells prevent lethal autoimmunity in IL-2Rbeta-deficient mice. Implications for the nonredundant function of IL-2
-
T.R. Malek, A. Yu, V. Vincek, P. Scibelli, and L. Kong CD4 regulatory T cells prevent lethal autoimmunity in IL-2Rbeta-deficient mice. Implications for the nonredundant function of IL-2 Immunity 17 2002 167 178
-
(2002)
Immunity
, vol.17
, pp. 167-178
-
-
Malek, T.R.1
Yu, A.2
Vincek, V.3
Scibelli, P.4
Kong, L.5
-
35
-
-
33847242598
-
Foxp3 occupancy and regulation of key target genes during T-cell stimulation
-
A. Marson, K. Kretschmer, G.M. Frampton, E.S. Jacobsen, J.K. Polansky, and K.D. MacIsaac Foxp3 occupancy and regulation of key target genes during T-cell stimulation Nature 445 2007 931 935
-
(2007)
Nature
, vol.445
, pp. 931-935
-
-
Marson, A.1
Kretschmer, K.2
Frampton, G.M.3
Jacobsen, E.S.4
Polansky, J.K.5
MacIsaac, K.D.6
-
36
-
-
33847220736
-
Genome-wide analysis of Foxp3 target genes in developing and mature regulatory T cells
-
Y. Zheng, S.Z. Josefowicz, A. Kas, T.T. Chu, M.A. Gavin, and A.Y. Rudensky Genome-wide analysis of Foxp3 target genes in developing and mature regulatory T cells Nature 445 2007 936 940
-
(2007)
Nature
, vol.445
, pp. 936-940
-
-
Zheng, Y.1
Josefowicz, S.Z.2
Kas, A.3
Chu, T.T.4
Gavin, M.A.5
Rudensky, A.Y.6
-
37
-
-
33847153417
-
Foxp3-dependent programme of regulatory T-cell differentiation
-
M.A. Gavin, J.P. Rasmussen, J.D. Fontenot, V. Vasta, V.C. Manganiello, and J.A. Beavo Foxp3-dependent programme of regulatory T-cell differentiation Nature 445 2007 771 775
-
(2007)
Nature
, vol.445
, pp. 771-775
-
-
Gavin, M.A.1
Rasmussen, J.P.2
Fontenot, J.D.3
Vasta, V.4
Manganiello, V.C.5
Beavo, J.A.6
-
38
-
-
36048978911
-
Foxp3 transcription-factor-dependent and -independent regulation of the regulatory T cell transcriptional signature
-
J.A. Hill, M. Feuerer, K. Tash, S. Haxhinasto, J. Perez, and R. Melamed Foxp3 transcription-factor-dependent and -independent regulation of the regulatory T cell transcriptional signature Immunity 27 2007 786 800
-
(2007)
Immunity
, vol.27
, pp. 786-800
-
-
Hill, J.A.1
Feuerer, M.2
Tash, K.3
Haxhinasto, S.4
Perez, J.5
Melamed, R.6
-
39
-
-
33947600584
-
Regulatory T cell development in the absence of functional Foxp3
-
W. Lin, D. Haribhai, L.M. Relland, N. Truong, M.R. Carlson, and C.B. Williams Regulatory T cell development in the absence of functional Foxp3 Nat Immunol 8 2007 359 368
-
(2007)
Nat Immunol
, vol.8
, pp. 359-368
-
-
Lin, W.1
Haribhai, D.2
Relland, L.M.3
Truong, N.4
Carlson, M.R.5
Williams, C.B.6
-
40
-
-
34247215187
-
Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1
-
M. Ono, M. Borde, V. Heissmeyer, M. Feuerer, A.D. Lapan, and J.C. Stroud Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1 Nature 446 2007 685 689
-
(2007)
Nature
, vol.446
, pp. 685-689
-
-
Ono, M.1
Borde, M.2
Heissmeyer, V.3
Feuerer, M.4
Lapan, A.D.5
Stroud, J.C.6
-
41
-
-
33746228122
-
FOXP3 controls regulatory T cell function through cooperation with NFAT
-
Y. Wu, M. Borde, V. Heissmeyer, M. Feuerer, A.D. Lapan, and J.C. Stroud FOXP3 controls regulatory T cell function through cooperation with NFAT Cell 126 2006 375 387
-
(2006)
Cell
, vol.126
, pp. 375-387
-
-
Wu, Y.1
Borde, M.2
Heissmeyer, V.3
Feuerer, M.4
Lapan, A.D.5
Stroud, J.C.6
-
42
-
-
43449135305
-
TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function
-
L. Zhou, J.E. Lopes, M.M. Chong, II Ivanov, R. Min, and G.D. Victora TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function Nature 453 2008 236 240
-
(2008)
Nature
, vol.453
, pp. 236-240
-
-
Zhou, L.1
Lopes, J.E.2
Chong, M.M.3
Ivanov, I.I.4
Min, R.5
Victora, G.D.6
-
45
-
-
17044430217
-
Identifying Foxp3-expressing suppressor T cells with a bicistronic reporter
-
Y.Y. Wan, and R.A. Flavell Identifying Foxp3-expressing suppressor T cells with a bicistronic reporter Proc Natl Acad Sci USA 102 2005 5126 5131
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 5126-5131
-
-
Wan, Y.Y.1
Flavell, R.A.2
-
47
-
-
29244435493
-
Inducing and expanding regulatory T cell populations by foreign antigen
-
K. Kretschmer, I. Apostolou, D. Hawiger, K. Khazaie, M.C. Nussenzweig, and H. von Boehmer Inducing and expanding regulatory T cell populations by foreign antigen Nat Immunol 6 2005 1219 1227
-
(2005)
Nat Immunol
, vol.6
, pp. 1219-1227
-
-
Kretschmer, K.1
Apostolou, I.2
Hawiger, D.3
Khazaie, K.4
Nussenzweig, M.C.5
Von Boehmer, H.6
-
48
-
-
38349095578
-
Smad3 and NFAT cooperate to induce Foxp3 expression through its enhancer
-
Y. Tone, K. Furuuchi, Y. Kojima, M.L. Tykocinski, M.I. Greene, and M. Tone Smad3 and NFAT cooperate to induce Foxp3 expression through its enhancer Nat Immunol 9 2008 194 202
-
(2008)
Nat Immunol
, vol.9
, pp. 194-202
-
-
Tone, Y.1
Furuuchi, K.2
Kojima, Y.3
Tykocinski, M.L.4
Greene, M.I.5
Tone, M.6
-
49
-
-
2542420993
-
In vivo instruction of suppressor commitment in naive T cells
-
I. Apostolou, and H. von Boehmer In vivo instruction of suppressor commitment in naive T cells J Exp Med 199 2004 1401 1408
-
(2004)
J Exp Med
, vol.199
, pp. 1401-1408
-
-
Apostolou, I.1
Von Boehmer, H.2
-
50
-
-
0035399985
-
+ CD4 T cells in vivo after induction of peripheral tolerance with intravenous or oral antigen
-
+ CD4 T cells in vivo after induction of peripheral tolerance with intravenous or oral antigen J Immunol 167 2001 188 195
-
(2001)
J Immunol
, vol.167
, pp. 188-195
-
-
Thorstenson, K.M.1
Khoruts, A.2
-
51
-
-
34547769253
-
All-trans retinoic acid mediates enhanced T reg cell growth, differentiation, and gut homing in the face of high levels of co-stimulation
-
M.J. Benson, K. Pino-Lagos, M. Rosemblatt, and R.J. Noelle All-trans retinoic acid mediates enhanced T reg cell growth, differentiation, and gut homing in the face of high levels of co-stimulation J Exp Med 204 2007 1765 1774
-
(2007)
J Exp Med
, vol.204
, pp. 1765-1774
-
-
Benson, M.J.1
Pino-Lagos, K.2
Rosemblatt, M.3
Noelle, R.J.4
-
52
-
-
33746379546
-
The role of the transcription factor Foxp3 in the development of regulatory T cells
-
J.M. Kim, and A. Rudensky The role of the transcription factor Foxp3 in the development of regulatory T cells Immunol Rev 212 2006 86 98
-
(2006)
Immunol Rev
, vol.212
, pp. 86-98
-
-
Kim, J.M.1
Rudensky, A.2
-
53
-
-
31144464767
-
Cutting edge: Deficiency in the E3 ubiquitin ligase Cbl-b results in a multifunctional defect in T cell TGF-beta sensitivity in vitro and in vivo
-
E.A. Wohlfert, L. Gorelik, R. Mittler, R.A. Flavell, and R.B. Clark Cutting edge: deficiency in the E3 ubiquitin ligase Cbl-b results in a multifunctional defect in T cell TGF-beta sensitivity in vitro and in vivo J Immunol 176 2006 1316 1320
-
(2006)
J Immunol
, vol.176
, pp. 1316-1320
-
-
Wohlfert, E.A.1
Gorelik, L.2
Mittler, R.3
Flavell, R.A.4
Clark, R.B.5
-
56
-
-
0027959893
-
Single IL-2-secreting precursor CD4 T cell can develop into either Th1 or Th2 cytokine secretion phenotype
-
S. Sad, and T.R. Mosmann Single IL-2-secreting precursor CD4 T cell can develop into either Th1 or Th2 cytokine secretion phenotype J Immunol 153 1994 3514 3522
-
(1994)
J Immunol
, vol.153
, pp. 3514-3522
-
-
Sad, S.1
Mosmann, T.R.2
-
57
-
-
0025951644
-
Transforming growth factor-beta and IL-4 cause helper T cell precursors to develop into distinct effector helper cells that differ in lymphokine secretion pattern and cell surface phenotype
-
S.L. Swain, G. Huston, S. Tonkonogy, and A. Weinberg Transforming growth factor-beta and IL-4 cause helper T cell precursors to develop into distinct effector helper cells that differ in lymphokine secretion pattern and cell surface phenotype J Immunol 147 1991 2991 3000
-
(1991)
J Immunol
, vol.147
, pp. 2991-3000
-
-
Swain, S.L.1
Huston, G.2
Tonkonogy, S.3
Weinberg, A.4
-
58
-
-
0033623339
-
TGF-beta1 down-regulates Th2 development and results in decreased IL-4-induced STAT6 activation and GATA-3 expression
-
V.L. Heath, E.E. Murphy, C. Crain, M.G. Tomlinson, and A. O'Garra TGF-beta1 down-regulates Th2 development and results in decreased IL-4-induced STAT6 activation and GATA-3 expression Eur J Immunol 30 2000 2639 2649
-
(2000)
Eur J Immunol
, vol.30
, pp. 2639-2649
-
-
Heath, V.L.1
Murphy, E.E.2
Crain, C.3
Tomlinson, M.G.4
O'Garra, A.5
-
59
-
-
0037013930
-
Mechanism of transforming growth factor beta-induced inhibition of T helper type 1 differentiation
-
L. Gorelik, S. Constant, and R.A. Flavell Mechanism of transforming growth factor beta-induced inhibition of T helper type 1 differentiation J Exp Med 195 2002 1499 1505
-
(2002)
J Exp Med
, vol.195
, pp. 1499-1505
-
-
Gorelik, L.1
Constant, S.2
Flavell, R.A.3
-
60
-
-
0034327176
-
Cutting edge: TGF-beta inhibits Th type 2 development through inhibition of GATA-3 expression
-
L. Gorelik, P.E. Fields, and R.A. Flavell Cutting edge: TGF-beta inhibits Th type 2 development through inhibition of GATA-3 expression J Immunol 165 2000 4773 4777
-
(2000)
J Immunol
, vol.165
, pp. 4773-4777
-
-
Gorelik, L.1
Fields, P.E.2
Flavell, R.A.3
-
61
-
-
34547757390
-
Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid
-
C.M. Sun, J.A. Hall, R.B. Blank, N. Bouladoux, M. Oukka, and J.R. Mora Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid J Exp Med 204 2007 1775 1785
-
(2007)
J Exp Med
, vol.204
, pp. 1775-1785
-
-
Sun, C.M.1
Hall, J.A.2
Blank, R.B.3
Bouladoux, N.4
Oukka, M.5
Mora, J.R.6
-
62
-
-
34547788180
-
A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism
-
J.L. Coombes, K.R. Siddiqui, C.V. Arancibia-Carcamo, J. Hall, C.M. Sun, and Y. Belkaid A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism J Exp Med 204 2007 1757 1764
-
(2007)
J Exp Med
, vol.204
, pp. 1757-1764
-
-
Coombes, J.L.1
Siddiqui, K.R.2
Arancibia-Carcamo, C.V.3
Hall, J.4
Sun, C.M.5
Belkaid, Y.6
-
64
-
-
64049110576
-
Retinoic acid can directly promote TGF-beta-mediated Foxp3(+) Treg cell conversion of naive T cells
-
D. Mucida, K. Pino-Lagos, G. Kim, E. Nowak, M.J. Benson, and M. Kronenberg Retinoic acid can directly promote TGF-beta-mediated Foxp3(+) Treg cell conversion of naive T cells Immunity 30 2009 471 472 author reply 472473
-
(2009)
Immunity
, vol.30
, pp. 471-472
-
-
Mucida, D.1
Pino-Lagos, K.2
Kim, G.3
Nowak, E.4
Benson, M.J.5
Kronenberg, M.6
-
65
-
-
34447265236
-
CREB/ATF-dependent T cell receptor-induced FoxP3 gene expression: A role for DNA methylation
-
H.P. Kim, and W.J. Leonard CREB/ATF-dependent T cell receptor-induced FoxP3 gene expression: a role for DNA methylation J Exp Med 204 2007 1543 1551
-
(2007)
J Exp Med
, vol.204
, pp. 1543-1551
-
-
Kim, H.P.1
Leonard, W.J.2
-
66
-
-
33644844341
-
Molecular mechanisms underlying FOXP3 induction in human T cells
-
P.Y. Mantel Molecular mechanisms underlying FOXP3 induction in human T cells J Immunol 176 2006 3593 3602
-
(2006)
J Immunol
, vol.176
, pp. 3593-3602
-
-
Mantel, P.Y.1
-
67
-
-
71749094333
-
Development of Foxp3(+) regulatory t cells is driven by the c-Rel enhanceosome
-
Q. Ruan, V. Kameswaran, Y. Tone, L. Li, H.C. Liou, and M.I. Greene Development of Foxp3(+) regulatory t cells is driven by the c-Rel enhanceosome Immunity 31 2009 932 940
-
(2009)
Immunity
, vol.31
, pp. 932-940
-
-
Ruan, Q.1
Kameswaran, V.2
Tone, Y.3
Li, L.4
Liou, H.C.5
Greene, M.I.6
-
69
-
-
40949123088
-
Dual functions for the endoplasmic reticulum calcium sensors STIM1 and STIM2 in T cell activation and tolerance
-
M. Oh-Hora, M. Yamashita, P.G. Hogan, S. Sharma, E. Lamperti, and W. Chung Dual functions for the endoplasmic reticulum calcium sensors STIM1 and STIM2 in T cell activation and tolerance Nat Immunol 9 2008 432 443
-
(2008)
Nat Immunol
, vol.9
, pp. 432-443
-
-
Oh-Hora, M.1
Yamashita, M.2
Hogan, P.G.3
Sharma, S.4
Lamperti, E.5
Chung, W.6
-
70
-
-
0023917345
-
Thymus and autoimmunity. Transplantation of the thymus from cyclosporin A-treated mice causes organ-specific autoimmune disease in athymic nude mice
-
S. Sakaguchi, and N. Sakaguchi Thymus and autoimmunity. Transplantation of the thymus from cyclosporin A-treated mice causes organ-specific autoimmune disease in athymic nude mice J Exp Med 167 1988 1479 1485
-
(1988)
J Exp Med
, vol.167
, pp. 1479-1485
-
-
Sakaguchi, S.1
Sakaguchi, N.2
-
71
-
-
0024589097
-
Organ-specific autoimmune disease induced in mice by elimination of T cell subsets. V. Neonatal administration of cyclosporin A causes autoimmune disease
-
S. Sakaguchi, and N. Sakaguchi Organ-specific autoimmune disease induced in mice by elimination of T cell subsets. V. Neonatal administration of cyclosporin A causes autoimmune disease J Immunol 142 1989 471 480
-
(1989)
J Immunol
, vol.142
, pp. 471-480
-
-
Sakaguchi, S.1
Sakaguchi, N.2
-
72
-
-
0032575574
-
A protein kinase C-, Ras-, and RSK2-dependent signal transduction pathway activates the cAMP-responsive element-binding protein transcription factor following T cell receptor engagement
-
N. Muthusamy, and J.M. Leiden A protein kinase C-, Ras-, and RSK2-dependent signal transduction pathway activates the cAMP-responsive element-binding protein transcription factor following T cell receptor engagement J Biol Chem 273 1998 22841 22847
-
(1998)
J Biol Chem
, vol.273
, pp. 22841-22847
-
-
Muthusamy, N.1
Leiden, J.M.2
-
73
-
-
33747801470
-
+ regulatory T cells through a STAT-dependent mechanism and induces the expansion of these cells in vivo
-
+ regulatory T cells through a STAT-dependent mechanism and induces the expansion of these cells in vivo Blood 108 2006 1571 1579
-
(2006)
Blood
, vol.108
, pp. 1571-1579
-
-
Zorn, E.1
Nelson, E.A.2
Mohseni, M.3
Porcheray, F.4
Kim, H.5
Litsa, D.6
-
74
-
-
65549100376
-
Cutting edge: TCR stimulation is sufficient for induction of Foxp3 expression in the absence of DNA methyltransferase 1
-
S.Z. Josefowicz, C.B. Wilson, and A.Y. Rudensky Cutting edge: TCR stimulation is sufficient for induction of Foxp3 expression in the absence of DNA methyltransferase 1 J Immunol 182 2009 6648 6652
-
(2009)
J Immunol
, vol.182
, pp. 6648-6652
-
-
Josefowicz, S.Z.1
Wilson, C.B.2
Rudensky, A.Y.3
-
76
-
-
70350451993
-
Runx-CBFbeta complexes control expression of the transcription factor Foxp3 in regulatory T cells
-
D. Rudra, T. Egawa, M.M. Chong, P. Treuting, D.R. Littman, and A.Y. Rudensky Runx-CBFbeta complexes control expression of the transcription factor Foxp3 in regulatory T cells Nat Immunol 10 2009 1170 1177
-
(2009)
Nat Immunol
, vol.10
, pp. 1170-1177
-
-
Rudra, D.1
Egawa, T.2
Chong, M.M.3
Treuting, P.4
Littman, D.R.5
Rudensky, A.Y.6
-
77
-
-
70449706325
-
Runx proteins regulate Foxp3 expression
-
L. Bruno, L. Mazzarella, M. Hoogenkamp, A. Hertweck, B.S. Cobb, and S. Sauer Runx proteins regulate Foxp3 expression J Exp Med 206 2009 2329 2337
-
(2009)
J Exp Med
, vol.206
, pp. 2329-2337
-
-
Bruno, L.1
Mazzarella, L.2
Hoogenkamp, M.3
Hertweck, A.4
Cobb, B.S.5
Sauer, S.6
-
80
-
-
33746111852
-
The kinase TAK1 integrates antigen and cytokine receptor signaling for T cell development, survival and function
-
Y.Y. Wan, H. Chi, M. Xie, M.D. Schneider, and R.A. Flavell The kinase TAK1 integrates antigen and cytokine receptor signaling for T cell development, survival and function Nat Immunol 7 2006 851 858
-
(2006)
Nat Immunol
, vol.7
, pp. 851-858
-
-
Wan, Y.Y.1
Chi, H.2
Xie, M.3
Schneider, M.D.4
Flavell, R.A.5
-
81
-
-
71749088574
-
Nuclear factor-kappaB modulates regulatory T cell development by directly regulating expression of Foxp3 transcription factor
-
M. Long, S.G. Park, I. Strickland, M.S. Hayden, and S. Ghosh Nuclear factor-kappaB modulates regulatory T cell development by directly regulating expression of Foxp3 transcription factor Immunity 31 2009 921 931
-
(2009)
Immunity
, vol.31
, pp. 921-931
-
-
Long, M.1
Park, S.G.2
Strickland, I.3
Hayden, M.S.4
Ghosh, S.5
-
83
-
-
27544446622
-
+ regulatory T cells in the absence of interleukin 2 signaling
-
+ regulatory T cells in the absence of interleukin 2 signaling Nat Immunol 6 2005 1152 1159
-
(2005)
Nat Immunol
, vol.6
, pp. 1152-1159
-
-
D'Cruz, L.M.1
Klein, L.2
-
84
-
-
34249933446
-
Tracing the action of IL-2 in tolerance to islet-specific antigen
-
A. Liston, O.M. Siggs, and C.C. Goodnow Tracing the action of IL-2 in tolerance to islet-specific antigen Immunol Cell Biol 85 2007 338 342
-
(2007)
Immunol Cell Biol
, vol.85
, pp. 338-342
-
-
Liston, A.1
Siggs, O.M.2
Goodnow, C.C.3
-
85
-
-
0031939403
-
+ T cells inhibit both the induction and effector function of autoreactive T cells and represent a unique lineage of immunoregulatory cells
-
+ T cells inhibit both the induction and effector function of autoreactive T cells and represent a unique lineage of immunoregulatory cells J Immunol 160 1998 1212 1218
-
(1998)
J Immunol
, vol.160
, pp. 1212-1218
-
-
Suri-Payer, E.1
Amar, A.Z.2
Thornton, A.M.3
Shevach, E.M.4
-
86
-
-
0031647622
-
+ CD4+ naturally anergic and suppressive T cells: Induction of autoimmune disease by breaking their anergic/suppressive state
-
+ CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state Int Immunol 10 1998 1969 1980
-
(1998)
Int Immunol
, vol.10
, pp. 1969-1980
-
-
Takahashi, T.1
Kuniyasu, Y.2
Toda, M.3
Sakaguchi, N.4
Itoh, M.5
Iwata, M.6
-
87
-
-
0031821875
-
+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production
-
+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production J Exp Med 188 1998 287 296
-
(1998)
J Exp Med
, vol.188
, pp. 287-296
-
-
Thornton, A.M.1
Shevach, E.M.2
-
88
-
-
65549136983
-
+ T regulatory cell-mediated suppression
-
+ T regulatory cell-mediated suppression Immunity 30 2009 636 645
-
(2009)
Immunity
, vol.30
, pp. 636-645
-
-
Shevach, E.M.1
-
90
-
-
29244482759
-
Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice
-
Q. Tang, J.Y. Adams, A.J. Tooley, M. Bi, B.T. Fife, and P. Serra Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice Nat Immunol 7 2006 83 92
-
(2006)
Nat Immunol
, vol.7
, pp. 83-92
-
-
Tang, Q.1
Adams, J.Y.2
Tooley, A.J.3
Bi, M.4
Fife, B.T.5
Serra, P.6
-
91
-
-
0034077559
-
+ regulatory T cells down-regulate co-stimulatory molecules on antigen-presenting cells
-
+ regulatory T cells down-regulate co-stimulatory molecules on antigen-presenting cells Eur J Immunol 30 2000 1538 1543
-
(2000)
Eur J Immunol
, vol.30
, pp. 1538-1543
-
-
Cederbom, L.1
Hall, H.2
Ivars, F.3
-
92
-
-
33646007957
-
+ CD25high regulatory T cells modulate myeloid but not plasmacytoid dendritic cells activation
-
+ CD25high regulatory T cells modulate myeloid but not plasmacytoid dendritic cells activation J Immunol 176 2006 5293 5298
-
(2006)
J Immunol
, vol.176
, pp. 5293-5298
-
-
Houot, R.1
Perrot, I.2
Garcia, E.3
Durand, I.4
Lebecque, S.5
-
94
-
-
33646487145
-
Modulation of dendritic cell function by naive and regulatory CD4+ T cells
-
M. Veldhoen, H. Moncrieffe, R.J. Hocking, C.J. Atkins, and B. Stockinger Modulation of dendritic cell function by naive and regulatory CD4+ T cells J Immunol 176 2006 6202 6210
-
(2006)
J Immunol
, vol.176
, pp. 6202-6210
-
-
Veldhoen, M.1
Moncrieffe, H.2
Hocking, R.J.3
Atkins, C.J.4
Stockinger, B.5
-
95
-
-
33846485153
-
Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice
-
J.M. Kim, J.P. Rasmussen, and A.Y. Rudensky Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice Nat Immunol 8 2007 191 197
-
(2007)
Nat Immunol
, vol.8
, pp. 191-197
-
-
Kim, J.M.1
Rasmussen, J.P.2
Rudensky, A.Y.3
-
96
-
-
65249089638
-
In vivo analysis of dendritic cell development and homeostasis
-
K. Liu, G.D. Victora, T.A. Schwickert, P. Guermonprez, M.M. Meredith, and K. Yao In vivo analysis of dendritic cell development and homeostasis Science 324 2009 392 397
-
(2009)
Science
, vol.324
, pp. 392-397
-
-
Liu, K.1
Victora, G.D.2
Schwickert, T.A.3
Guermonprez, P.4
Meredith, M.M.5
Yao, K.6
-
98
-
-
0033571105
-
+ CD4+ T cells: A common basis between tumor immunity and autoimmunity
-
+ CD4+ T cells: a common basis between tumor immunity and autoimmunity J Immunol 163 1999 5211 5218
-
(1999)
J Immunol
, vol.163
, pp. 5211-5218
-
-
Shimizu, J.1
Yamazaki, S.2
Sakaguchi, S.3
-
99
-
-
0033168037
-
Tumor rejection by in vivo administration of anti-CD25 (interleukin-2 receptor alpha) monoclonal antibody
-
S. Onizuka, I. Tawara, J. Shimizu, S. Sakaguchi, T. Fujita, and E. Nakayama Tumor rejection by in vivo administration of anti-CD25 (interleukin-2 receptor alpha) monoclonal antibody Cancer Res 59 1999 3128 3133
-
(1999)
Cancer Res
, vol.59
, pp. 3128-3133
-
-
Onizuka, S.1
Tawara, I.2
Shimizu, J.3
Sakaguchi, S.4
Fujita, T.5
Nakayama, E.6
-
100
-
-
0036093489
-
+ regulatory cells augments the generation of specific immune T cells in tumor-draining lymph nodes
-
+ regulatory cells augments the generation of specific immune T cells in tumor-draining lymph nodes J Immunother 25 2002 207 217
-
(2002)
J Immunother
, vol.25
, pp. 207-217
-
-
Tanaka, H.1
Tanaka, J.2
Kjaergaard, J.3
Shu, S.4
-
101
-
-
33745978399
-
Regulatory T cells reversibly suppress cytotoxic T cell function independent of effector differentiation
-
T.R. Mempel, M.J. Pittet, K. Khazaie, W. Weninger, R. Weissleder, and H. von Boehmer Regulatory T cells reversibly suppress cytotoxic T cell function independent of effector differentiation Immunity 25 2006 129 141
-
(2006)
Immunity
, vol.25
, pp. 129-141
-
-
Mempel, T.R.1
Pittet, M.J.2
Khazaie, K.3
Weninger, W.4
Weissleder, R.5
Von Boehmer, H.6
-
102
-
-
12244285937
-
Regulatory T cells suppress tumor-specific CD8 T cell cytotoxicity through TGF-beta signals in vivo
-
M.L. Chen, M.J. Pittet, L. Gorelik, R.A. Flavell, R. Weissleder, and H. von Boehmer Regulatory T cells suppress tumor-specific CD8 T cell cytotoxicity through TGF-beta signals in vivo Proc Natl Acad Sci USA 102 2005 419 424
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 419-424
-
-
Chen, M.L.1
Pittet, M.J.2
Gorelik, L.3
Flavell, R.A.4
Weissleder, R.5
Von Boehmer, H.6
-
103
-
-
0035153463
-
Role of transforming growth factor beta in cancer
-
B. Pasche Role of transforming growth factor beta in cancer J Cell Physiol 186 2001 153 168
-
(2001)
J Cell Physiol
, vol.186
, pp. 153-168
-
-
Pasche, B.1
-
107
-
-
0037312480
-
Increase of regulatory T cells in the peripheral blood of cancer patients
-
A.M. Wolf, D. Wolf, M. Steurer, G. Gastl, E. Gunsilius, and B. Grubeck-Loebenstein Increase of regulatory T cells in the peripheral blood of cancer patients Clin Cancer Res 9 2003 606 612
-
(2003)
Clin Cancer Res
, vol.9
, pp. 606-612
-
-
Wolf, A.M.1
Wolf, D.2
Steurer, M.3
Gastl, G.4
Gunsilius, E.5
Grubeck-Loebenstein, B.6
-
109
-
-
33646397029
-
+ T regulatory cells inhibit cytotoxic activity of CTL and NK cells in humans-impact of immunosenescence
-
+ T regulatory cells inhibit cytotoxic activity of CTL and NK cells in humans-impact of immunosenescence Clin Immunol 119 2006 307 316
-
(2006)
Clin Immunol
, vol.119
, pp. 307-316
-
-
Trzonkowski, P.1
Szmit, E.2
Mysliwska, J.3
Mysliwski, A.4
-
111
-
-
0033105648
-
Cellular and molecular characterization of the scurfy mouse mutant
-
L.B. Clark, M.W. Appleby, M.E. Brunkow, J.E. Wilkinson, S.F. Ziegler, and F. Ramsdell Cellular and molecular characterization of the scurfy mouse mutant J Immunol 162 1999 2546 2554
-
(1999)
J Immunol
, vol.162
, pp. 2546-2554
-
-
Clark, L.B.1
Appleby, M.W.2
Brunkow, M.E.3
Wilkinson, J.E.4
Ziegler, S.F.5
Ramsdell, F.6
-
113
-
-
0035198252
-
B cells and professional APCs recruit regulatory T cells via CCL4
-
R.S. Bystry, V. Aluvihare, K.A. Welch, M. Kallikourdis, and A.G. Betz B cells and professional APCs recruit regulatory T cells via CCL4 Nat Immunol 2 2001 1126 1132
-
(2001)
Nat Immunol
, vol.2
, pp. 1126-1132
-
-
Bystry, R.S.1
Aluvihare, V.2
Welch, K.A.3
Kallikourdis, M.4
Betz, A.G.5
-
115
-
-
0034131557
-
Abrogation of TGFbeta signaling in T cells leads to spontaneous T cell differentiation and autoimmune disease
-
L. Gorelik, and R.A. Flavell Abrogation of TGFbeta signaling in T cells leads to spontaneous T cell differentiation and autoimmune disease Immunity 12 2000 171 181
-
(2000)
Immunity
, vol.12
, pp. 171-181
-
-
Gorelik, L.1
Flavell, R.A.2
-
116
-
-
34248592104
-
T cell-produced transforming growth factor-beta1 controls T cell tolerance and regulates Th1- and Th17-cell differentiation
-
M.O. Li, Y.Y. Wan, and R.A. Flavell T cell-produced transforming growth factor-beta1 controls T cell tolerance and regulates Th1- and Th17-cell differentiation Immunity 26 2007 579 591
-
(2007)
Immunity
, vol.26
, pp. 579-591
-
-
Li, M.O.1
Wan, Y.Y.2
Flavell, R.A.3
-
117
-
-
0035801335
-
Cell contact-dependent immunosuppression by CD4(+)CD25(+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta
-
K. Nakamura, A. Kitani, and W. Strober Cell contact-dependent immunosuppression by CD4(+)CD25(+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta J Exp Med 194 2001 629 644
-
(2001)
J Exp Med
, vol.194
, pp. 629-644
-
-
Nakamura, K.1
Kitani, A.2
Strober, W.3
-
118
-
-
0037099613
-
CD4(+)CD25(+) regulatory T cells can mediate suppressor function in the absence of transforming growth factor beta1 production and responsiveness
-
C.A. Piccirillo, J.J. Letterio, A.M. Thornton, R.S. McHugh, M. Mamura, and H. Mizuhara CD4(+)CD25(+) regulatory T cells can mediate suppressor function in the absence of transforming growth factor beta1 production and responsiveness J Exp Med 196 2002 237 246
-
(2002)
J Exp Med
, vol.196
, pp. 237-246
-
-
Piccirillo, C.A.1
Letterio, J.J.2
Thornton, A.M.3
McHugh, R.S.4
Mamura, M.5
Mizuhara, H.6
-
119
-
-
0027521572
-
Interleukin-10-deficient mice develop chronic enterocolitis
-
R. Kuhn, J. Lohler, D. Rennick, K. Rajewsky, and W. Muller Interleukin-10-deficient mice develop chronic enterocolitis Cell 75 1993 263 274
-
(1993)
Cell
, vol.75
, pp. 263-274
-
-
Kuhn, R.1
Lohler, J.2
Rennick, D.3
Rajewsky, K.4
Muller, W.5
-
120
-
-
9244237038
-
T cell-specific inactivation of the interleukin 10 gene in mice results in enhanced T cell responses but normal innate responses to lipopolysaccharide or skin irritation
-
A. Roers, L. Siewe, E. Strittmatter, M. Deckert, D. Schluter, and W. Stenzel T cell-specific inactivation of the interleukin 10 gene in mice results in enhanced T cell responses but normal innate responses to lipopolysaccharide or skin irritation J Exp Med 200 2004 1289 1297
-
(2004)
J Exp Med
, vol.200
, pp. 1289-1297
-
-
Roers, A.1
Siewe, L.2
Strittmatter, E.3
Deckert, M.4
Schluter, D.5
Stenzel, W.6
-
121
-
-
41549159660
-
Regulatory T cell-derived interleukin-10 limits inflammation at environmental interfaces
-
Y.P. Rubtsov, J.P. Rasmussen, E.Y. Chi, J. Fontenot, L. Castelli, and X. Ye Regulatory T cell-derived interleukin-10 limits inflammation at environmental interfaces Immunity 28 2008 546 558
-
(2008)
Immunity
, vol.28
, pp. 546-558
-
-
Rubtsov, Y.P.1
Rasmussen, J.P.2
Chi, E.Y.3
Fontenot, J.4
Castelli, L.5
Ye, X.6
-
122
-
-
0033523607
-
An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation
-
C. Asseman, S. Mauze, M.W. Leach, R.L. Coffman, and F. Powrie An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation J Exp Med 190 1999 995 1004
-
(1999)
J Exp Med
, vol.190
, pp. 995-1004
-
-
Asseman, C.1
Mauze, S.2
Leach, M.W.3
Coffman, R.L.4
Powrie, F.5
-
123
-
-
0030942666
-
Altered immune responses in interleukin 10 transgenic mice
-
A. Hagenbaugh, S. Sharma, S.M. Dubinett, S.H. Wei, R. Aranda, and H. Cheroutre Altered immune responses in interleukin 10 transgenic mice J Exp Med 185 1997 2101 2110
-
(1997)
J Exp Med
, vol.185
, pp. 2101-2110
-
-
Hagenbaugh, A.1
Sharma, S.2
Dubinett, S.M.3
Wei, S.H.4
Aranda, R.5
Cheroutre, H.6
-
125
-
-
33745317769
-
Cutting edge: Induction of B7-H4 on APCs through IL-10: Novel suppressive mode for regulatory T cells
-
I. Kryczek, S. Wei, L. Zou, G. Zhu, P. Mottram, and H. Xu Cutting edge: induction of B7-H4 on APCs through IL-10: novel suppressive mode for regulatory T cells J Immunol 177 2006 40 44
-
(2006)
J Immunol
, vol.177
, pp. 40-44
-
-
Kryczek, I.1
Wei, S.2
Zou, L.3
Zhu, G.4
Mottram, P.5
Xu, H.6
-
126
-
-
0344299189
-
Cutting edge: Lymphoproliferative disease in the absence of CTLA-4 is not T cell autonomous
-
M.F. Bachmann, G. Kohler, B. Ecabert, T.W. Mak, and M. Kopf Cutting edge: lymphoproliferative disease in the absence of CTLA-4 is not T cell autonomous J Immunol 163 1999 1128 1131
-
(1999)
J Immunol
, vol.163
, pp. 1128-1131
-
-
Bachmann, M.F.1
Kohler, G.2
Ecabert, B.3
Mak, T.W.4
Kopf, M.5
-
127
-
-
0034679567
-
Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation
-
S. Read, V. Malmstrom, and F. Powrie Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation J Exp Med 192 2000 295 302
-
(2000)
J Exp Med
, vol.192
, pp. 295-302
-
-
Read, S.1
Malmstrom, V.2
Powrie, F.3
-
128
-
-
0034679560
-
Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4
-
T. Takahashi, T. Tagami, S. Yamazaki, T. Uede, J. Shimizu, and N. Sakaguchi Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4 J Exp Med 192 2000 303 310
-
(2000)
J Exp Med
, vol.192
, pp. 303-310
-
-
Takahashi, T.1
Tagami, T.2
Yamazaki, S.3
Uede, T.4
Shimizu, J.5
Sakaguchi, N.6
-
129
-
-
0025830902
-
CTLA-4 is a second receptor for the B cell activation antigen B7
-
P.S. Linsley, W. Brady, M. Urnes, L.S. Grosmaire, N.K. Damle, and J.A. Ledbetter CTLA-4 is a second receptor for the B cell activation antigen B7 J Exp Med 174 1991 561 569
-
(1991)
J Exp Med
, vol.174
, pp. 561-569
-
-
Linsley, P.S.1
Brady, W.2
Urnes, M.3
Grosmaire, L.S.4
Damle, N.K.5
Ledbetter, J.A.6
-
130
-
-
0027937702
-
Complementarity determining region 1 (CDR1)- and CDR3-analogous regions in CTLA-4 and CD28 determine the binding to B7-1
-
R.J. Peach, J. Bajorath, W. Brady, G. Leytze, J. Greene, and J. Naemura Complementarity determining region 1 (CDR1)- and CDR3-analogous regions in CTLA-4 and CD28 determine the binding to B7-1 J Exp Med 180 1994 2049 2058
-
(1994)
J Exp Med
, vol.180
, pp. 2049-2058
-
-
Peach, R.J.1
Bajorath, J.2
Brady, W.3
Leytze, G.4
Greene, J.5
Naemura, J.6
-
131
-
-
0029953858
-
CTLA-4 ligation blocks CD28-dependent T cell activation
-
T.L. Walunas, C.Y. Bakker, and J.A. Bluestone CTLA-4 ligation blocks CD28-dependent T cell activation J Exp Med 183 1996 2541 2550
-
(1996)
J Exp Med
, vol.183
, pp. 2541-2550
-
-
Walunas, T.L.1
Bakker, C.Y.2
Bluestone, J.A.3
-
132
-
-
0031154577
-
CTLA4Ig prevents lymphoproliferation and fatal multiorgan tissue destruction in CTLA-4-deficient mice
-
E.A. Tivol, S.D. Boyd, S. McKeon, F. Borriello, P. Nickerson, and T.B. Strom CTLA4Ig prevents lymphoproliferation and fatal multiorgan tissue destruction in CTLA-4-deficient mice J Immunol 158 1997 5091 5094
-
(1997)
J Immunol
, vol.158
, pp. 5091-5094
-
-
Tivol, E.A.1
Boyd, S.D.2
McKeon, S.3
Borriello, F.4
Nickerson, P.5
Strom, T.B.6
-
133
-
-
0030694234
-
The emerging role of CTLA-4 as an immune attenuator
-
C.B. Thompson, and J.P. Allison The emerging role of CTLA-4 as an immune attenuator Immunity 7 1997 445 450
-
(1997)
Immunity
, vol.7
, pp. 445-450
-
-
Thompson, C.B.1
Allison, J.P.2
-
134
-
-
0346119234
-
Modulation of tryptophan catabolism by regulatory T cells
-
F. Fallarino, U. Grohmann, K.W. Hwang, C. Orabona, C. Vacca, and R. Bianchi Modulation of tryptophan catabolism by regulatory T cells Nat Immunol 4 2003 1206 1212
-
(2003)
Nat Immunol
, vol.4
, pp. 1206-1212
-
-
Fallarino, F.1
Grohmann, U.2
Hwang, K.W.3
Orabona, C.4
Vacca, C.5
Bianchi, R.6
-
135
-
-
0036852170
-
CTLA-4-Ig regulates tryptophan catabolism in vivo
-
U. Grohmann, C. Orabona, F. Fallarino, C. Vacca, F. Calcinaro, and A. Falorni CTLA-4-Ig regulates tryptophan catabolism in vivo Nat Immunol 3 2002 1097 1101
-
(2002)
Nat Immunol
, vol.3
, pp. 1097-1101
-
-
Grohmann, U.1
Orabona, C.2
Fallarino, F.3
Vacca, C.4
Calcinaro, F.5
Falorni, A.6
-
136
-
-
0034176031
-
Indoleamine 2, 3-dioxygenase production by human dendritic cells results in the inhibition of T cell proliferation
-
P. Hwu, M.X. Du, R. Lapointe, M. Do, M.W. Taylor, and H.A. Young Indoleamine 2, 3-dioxygenase production by human dendritic cells results in the inhibition of T cell proliferation J Immunol 164 2000 3596 3599
-
(2000)
J Immunol
, vol.164
, pp. 3596-3599
-
-
Hwu, P.1
Du, M.X.2
Lapointe, R.3
Do, M.4
Taylor, M.W.5
Young, H.A.6
-
137
-
-
0033519278
-
Inhibition of T cell proliferation by macrophage tryptophan catabolism
-
D.H. Munn, E. Shafizadeh, J.T. Attwood, I. Bondarev, A. Pashine, and A.L. Mellor Inhibition of T cell proliferation by macrophage tryptophan catabolism J Exp Med 189 1999 1363 1372
-
(1999)
J Exp Med
, vol.189
, pp. 1363-1372
-
-
Munn, D.H.1
Shafizadeh, E.2
Attwood, J.T.3
Bondarev, I.4
Pashine, A.5
Mellor, A.L.6
-
138
-
-
9244231842
-
CD28 induces immunostimulatory signals in dendritic cells via CD80 and CD86
-
C. Orabona, U. Grohmann, M.L. Belladonna, F. Fallarino, C. Vacca, and R. Bianchi CD28 induces immunostimulatory signals in dendritic cells via CD80 and CD86 Nat Immunol 5 2004 1134 1142
-
(2004)
Nat Immunol
, vol.5
, pp. 1134-1142
-
-
Orabona, C.1
Grohmann, U.2
Belladonna, M.L.3
Fallarino, F.4
Vacca, C.5
Bianchi, R.6
-
139
-
-
0037436119
-
+ T cell-mediated suppression by dendritic cells
-
+ T cell-mediated suppression by dendritic cells Science 299 2003 1033 1036
-
(2003)
Science
, vol.299
, pp. 1033-1036
-
-
Pasare, C.1
Medzhitov, R.2
-
140
-
-
48249103057
-
+ natural regulatory T cells preferentially form aggregates on dendritic cells in vitro and actively inhibit their maturation
-
+ natural regulatory T cells preferentially form aggregates on dendritic cells in vitro and actively inhibit their maturation Proc Natl Acad Sci USA 105 2008 10113 10118
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 10113-10118
-
-
Onishi, Y.1
Fehervari, Z.2
Yamaguchi, T.3
Sakaguchi, S.4
-
142
-
-
0027511603
-
Functional expression of B7/BB1 on activated T lymphocytes
-
M. Azuma, H. Yssel, J.H. Phillips, H. Spits, and L.L. Lanier Functional expression of B7/BB1 on activated T lymphocytes J Exp Med 177 1993 845 850
-
(1993)
J Exp Med
, vol.177
, pp. 845-850
-
-
Azuma, M.1
Yssel, H.2
Phillips, J.H.3
Spits, H.4
Lanier, L.L.5
-
143
-
-
0027473759
-
B7/BB1, the ligand for CD28, is expressed on repeatedly activated human T cells in vitro
-
D.M. Sansom, and N.D. Hall B7/BB1, the ligand for CD28, is expressed on repeatedly activated human T cells in vitro Eur J Immunol 23 1993 295 298
-
(1993)
Eur J Immunol
, vol.23
, pp. 295-298
-
-
Sansom, D.M.1
Hall, N.D.2
-
144
-
-
0347994958
-
B7 expression on T cells down-regulates immune responses through CTLA-4 ligation via T-T interactions [corrections]
-
P.A. Taylor, C.J. Lees, S. Fournier, J.P. Allison, A.H. Sharpe, and B.R. Blazar B7 expression on T cells down-regulates immune responses through CTLA-4 ligation via T-T interactions [corrections] J Immunol 172 2004 34 39
-
(2004)
J Immunol
, vol.172
, pp. 34-39
-
-
Taylor, P.A.1
Lees, C.J.2
Fournier, S.3
Allison, J.P.4
Sharpe, A.H.5
Blazar, B.R.6
-
145
-
-
3142708571
-
Engagement of B7 on effector T cells by regulatory T cells prevents autoimmune disease
-
S. Paust, L. Lu, N. McCarty, and H. Cantor Engagement of B7 on effector T cells by regulatory T cells prevents autoimmune disease Proc Natl Acad Sci USA 101 2004 10398 10403
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 10398-10403
-
-
Paust, S.1
Lu, L.2
McCarty, N.3
Cantor, H.4
-
146
-
-
0031803215
-
Characterization of human fibroleukin, a fibrinogen-like protein secreted by T lymphocytes
-
S. Marazzi, S. Blum, R. Hartmann, D. Gundersen, M. Schreyer, and S. Argraves Characterization of human fibroleukin, a fibrinogen-like protein secreted by T lymphocytes J Immunol 161 1998 138 147
-
(1998)
J Immunol
, vol.161
, pp. 138-147
-
-
Marazzi, S.1
Blum, S.2
Hartmann, R.3
Gundersen, D.4
Schreyer, M.5
Argraves, S.6
-
148
-
-
0037446535
-
Soluble fibrinogen-like protein 2/fibroleukin exhibits immunosuppressive properties: Suppressing T cell proliferation and inhibiting maturation of bone marrow-derived dendritic cells
-
C.W. Chan Soluble fibrinogen-like protein 2/fibroleukin exhibits immunosuppressive properties: suppressing T cell proliferation and inhibiting maturation of bone marrow-derived dendritic cells J Immunol 170 2003 4036 4044
-
(2003)
J Immunol
, vol.170
, pp. 4036-4044
-
-
Chan, C.W.1
-
149
-
-
40149102880
-
Targeted deletion of fgl2 leads to impaired regulatory T cell activity and development of autoimmune glomerulonephritis
-
I. Shalev, H. Liu, C. Koscik, A. Bartczak, M. Javadi, and K.M. Wong Targeted deletion of fgl2 leads to impaired regulatory T cell activity and development of autoimmune glomerulonephritis J Immunol 180 2008 249 260
-
(2008)
J Immunol
, vol.180
, pp. 249-260
-
-
Shalev, I.1
Liu, H.2
Koscik, C.3
Bartczak, A.4
Javadi, M.5
Wong, K.M.6
-
151
-
-
5644302161
-
Human T regulatory cells can use the perforin pathway to cause autologous target cell death
-
W.J. Grossman, J.W. Verbsky, W. Barchet, M. Colonna, J.P. Atkinson, and T.J. Ley Human T regulatory cells can use the perforin pathway to cause autologous target cell death Immunity 21 2004 589 601
-
(2004)
Immunity
, vol.21
, pp. 589-601
-
-
Grossman, W.J.1
Verbsky, J.W.2
Barchet, W.3
Colonna, M.4
Atkinson, J.P.5
Ley, T.J.6
-
152
-
-
0033499729
-
Cytosolic delivery of granzyme B by bacterial toxins: Evidence that endosomal disruption, in addition to transmembrane pore formation, is an important function of perforin
-
K.A. Browne, E. Blink, V.R. Sutton, C.J. Froelich, D.A. Jans, and J.A. Trapani Cytosolic delivery of granzyme B by bacterial toxins: evidence that endosomal disruption, in addition to transmembrane pore formation, is an important function of perforin Mol Cell Biol 19 1999 8604 8615
-
(1999)
Mol Cell Biol
, vol.19
, pp. 8604-8615
-
-
Browne, K.A.1
Blink, E.2
Sutton, V.R.3
Froelich, C.J.4
Jans, D.A.5
Trapani, J.A.6
-
153
-
-
34250351459
-
Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression
-
S. Deaglio, K.M. Dwyer, W. Gao, D. Friedman, A. Usheva, and A. Erat Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression J Exp Med 204 2007 1257 1265
-
(2007)
J Exp Med
, vol.204
, pp. 1257-1265
-
-
Deaglio, S.1
Dwyer, K.M.2
Gao, W.3
Friedman, D.4
Usheva, A.5
Erat, A.6
-
154
-
-
33750832563
-
T regulatory and primed uncommitted CD4 T cells express CD73, which suppresses effector CD4 T cells by converting 5′-adenosine monophosphate to adenosine
-
J.J. Kobie, P.R. Shah, L. Yang, J.A. Rebhahn, D.J. Fowell, and T.R. Mosmann T regulatory and primed uncommitted CD4 T cells express CD73, which suppresses effector CD4 T cells by converting 5′-adenosine monophosphate to adenosine J Immunol 177 2006 6780 6786
-
(2006)
J Immunol
, vol.177
, pp. 6780-6786
-
-
Kobie, J.J.1
Shah, P.R.2
Yang, L.3
Rebhahn, J.A.4
Fowell, D.J.5
Mosmann, T.R.6
-
155
-
-
0035216666
-
CAMP-elevating agents suppress dendritic cell function
-
T. Kambayashi, R.P. Wallin, and H.G. Ljunggren cAMP-elevating agents suppress dendritic cell function J Leukoc Biol 70 2001 903 910
-
(2001)
J Leukoc Biol
, vol.70
, pp. 903-910
-
-
Kambayashi, T.1
Wallin, R.P.2
Ljunggren, H.G.3
-
156
-
-
0034848771
-
Expression and function of adenosine receptors in human dendritic cells
-
E. Panther, M. Idzko, Y. Herouy, H. Rheinen, P.J. Gebicke-Haerter, and U. Mrowietz Expression and function of adenosine receptors in human dendritic cells FASEB J 15 2001 1963 1970
-
(2001)
FASEB J
, vol.15
, pp. 1963-1970
-
-
Panther, E.1
Idzko, M.2
Herouy, Y.3
Rheinen, H.4
Gebicke-Haerter, P.J.5
Mrowietz, U.6
|