T cell-specific inactivation of the interleukin 10 gene in mice results in enhanced T cell responses but normal innate responses to lipopolysaccharide or skin irritation

Journal of Experimental Medicine

Volumn 200, Issue 10, 2004, Pages 1289-1297

  Roers, Axel ^a   Siewe, Lisa ^a   Strittmatter, Elke ^a   Deckert, Martina ^a   Schlüter, Dirk ^b,c   Stenzel, Werner ^a   Gruber, Achim D ^d   Krieg, Thomas ^a   Rajewsky, Klaus ^e   Müller, Werner ^f  

^a UNIVERSITY OF COLOGNE   (Germany)

^b OTTO VON GUERICKE UNIVERSITY   (Germany)

^c UNIVERSITY OF HEIDELBERG   (Germany)

^d UNIVERSITY OF VETERINARY MEDICINE HANNOVER   (Germany)

^e HARVARD MEDICAL SCHOOL   (United States)

^f HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

Author keywords

Allergic contact dermatitis; Cytokines; Gene targeting; Inflammation; Inflammatory bowel disease

Indexed keywords

CD4 ANTIGEN; CYTOKINE; DNA; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 10 RECEPTOR; INTERLEUKIN 12; INTERLEUKIN 2 RECEPTOR; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; CELL TYPE; CONTACT ALLERGY; CONTACT DERMATITIS; CONTROLLED STUDY; ENTERITIS; GENE TARGETING; IMMUNE RESPONSE; IMMUNOPATHOLOGY; INFLAMMATION; INTESTINE EPITHELIUM CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; SKIN IRRITATION; SPLEEN CELL; T LYMPHOCYTE; TOXOPLASMA GONDII;

ANIMALS; GENE SILENCING; HISTOLOGICAL TECHNIQUES; IMMUNITY, CELLULAR; IMMUNITY, NATURAL; INTERLEUKIN-10; INTESTINAL MUCOSA; LIPOPOLYSACCHARIDES; MICE; MICE, TRANSGENIC; MUTAGENESIS, INSERTIONAL; SKIN IRRITANCY TESTS; SPLEEN; T-LYMPHOCYTES; TOXOPLASMA;

EID: 9244237038     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20041789     Document Type: Article

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