-
1
-
-
0027369395
-
Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene
-
Sadlack, B., H. Merz, H. Schorle, A. Schimpl, A. C. Feller, and I. Horak. 1993. Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene. Cell 75: 253-261.
-
(1993)
Cell
, vol.75
, pp. 253-261
-
-
Sadlack, B.1
Merz, H.2
Schorle, H.3
Schimpl, A.4
Feller, A.C.5
Horak, I.6
-
2
-
-
0028784289
-
Interleukin-2 receptor α-chain regulates the size and content of the peripheral lymphoid compartment
-
Willerford, D. M., J. Chen, J. A. Ferry, L. Davidson, A. Ma, and F. W. Alt. 1995. Interleukin-2 receptor α-chain regulates the size and content of the peripheral lymphoid compartment. Immunity 3: 521-530.
-
(1995)
Immunity
, vol.3
, pp. 521-530
-
-
Willerford, D.M.1
Chen, J.2
Ferry, J.A.3
Davidson, L.4
Ma, A.5
Alt, F.W.6
-
3
-
-
0029028363
-
Deregulated T cell activation and autoimmunity in mice lacking interleukin-2 receptor β
-
Suzuki, H., T. M. Kundig, C. Furlonger, A. Wakeham, E. Timms, T. Matsuyama, R. Schmits, J. J. Simard, P. S. Ohashi, H. Griesser, et al. 1995. Deregulated T cell activation and autoimmunity in mice lacking interleukin-2 receptor β. Science 268: 1472-1476.
-
(1995)
Science
, vol.268
, pp. 1472-1476
-
-
Suzuki, H.1
Kundig, T.M.2
Furlonger, C.3
Wakeham, A.4
Timms, E.5
Matsuyama, T.6
Schmits, R.7
Simard, J.J.8
Ohashi, P.S.9
Griesser, H.10
-
4
-
-
0036669298
-
CD4 regulatory T cells prevent lethal autoimmunity in IL-2Rβ-deficient mice. Implications for the nonredundant function of IL-2
-
Malek, T. R., A. Yu, V. Vincek, P. Scibelli, and L. Kong. 2002. CD4 regulatory T cells prevent lethal autoimmunity in IL-2Rβ-deficient mice. Implications for the nonredundant function of IL-2. Immunity 17: 167-178.
-
(2002)
Immunity
, vol.17
, pp. 167-178
-
-
Malek, T.R.1
Yu, A.2
Vincek, V.3
Scibelli, P.4
Kong, L.5
-
5
-
-
0034654319
-
Normal lymphoid homeostasis and lack of lethal autoimmunity in mice containing mature T cells with severely impaired IL-2 receptors
-
Malek, T. R., B. O. Porter, E. K. Codias, P. Scibelli, and A. Yu. 2000. Normal lymphoid homeostasis and lack of lethal autoimmunity in mice containing mature T cells with severely impaired IL-2 receptors. J. Immunol. 164: 2905-2914.
-
(2000)
J. Immunol
, vol.164
, pp. 2905-2914
-
-
Malek, T.R.1
Porter, B.O.2
Codias, E.K.3
Scibelli, P.4
Yu, A.5
-
6
-
-
15444374646
-
+ regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization
-
+ regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization. J. Exp. Med. 201: 723-735.
-
(2005)
J. Exp. Med
, vol.201
, pp. 723-735
-
-
Setoguchi, R.1
Hori, S.2
Takahashi, T.3
Sakaguchi, S.4
-
7
-
-
27544446622
-
+ regulatory T cells in the absence of interleukin 2 signaling
-
+ regulatory T cells in the absence of interleukin 2 signaling. Nat Immunol. 6: 1152-1159.
-
(2005)
Nat Immunol
, vol.6
, pp. 1152-1159
-
-
D'Cruz, L.M.1
Klein, L.2
-
8
-
-
27544481941
-
A function for interleukin 2 in Foxp3-expressing regulatory T cells
-
Fontenot, J. D., J. P. Rasmussen, M. A. Gavin, and A. Y. Rudensky. 2005. A function for interleukin 2 in Foxp3-expressing regulatory T cells. Nat. Immunol. 6: 1142-1151.
-
(2005)
Nat. Immunol
, vol.6
, pp. 1142-1151
-
-
Fontenot, J.D.1
Rasmussen, J.P.2
Gavin, M.A.3
Rudensky, A.Y.4
-
12
-
-
0347785480
-
Control of regulatory T cell development by the transcription factor Foxp3
-
Hori, S., T. Nomura, and S. Sakaguchi. 2003. Control of regulatory T cell development by the transcription factor Foxp3. Science 299: 1057-1061.
-
(2003)
Science
, vol.299
, pp. 1057-1061
-
-
Hori, S.1
Nomura, T.2
Sakaguchi, S.3
-
15
-
-
0034526617
-
JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome
-
Chatila, T. A., F. Blaeser, N. Ho, H. M. Lederman, C. Voulgaropoulos, C. Helms, and A. M. Bowcock. 2000. JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome. J. Clin. Invest. 106: R75-R81.
-
(2000)
J. Clin. Invest
, vol.106
-
-
Chatila, T.A.1
Blaeser, F.2
Ho, N.3
Lederman, H.M.4
Voulgaropoulos, C.5
Helms, C.6
Bowcock, A.M.7
-
16
-
-
0035163909
-
X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy
-
Wildin, R. S., F. Ramsdell, J. Peake, F. Faravelli, J. L. Casanova, N. Buist, E. Levy-Lahad, M. Mazzella, O. Goulet, L. Perroni, et al. 2001. X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy. Nat. Genet. 27: 18-20.
-
(2001)
Nat. Genet
, vol.27
, pp. 18-20
-
-
Wildin, R.S.1
Ramsdell, F.2
Peake, J.3
Faravelli, F.4
Casanova, J.L.5
Buist, N.6
Levy-Lahad, E.7
Mazzella, M.8
Goulet, O.9
Perroni, L.10
-
17
-
-
0035167967
-
The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3
-
Bennett, C. L., J. Christie, F. Ramsdell, M. E. Brunkow, P. J. Ferguson, L. Whitesell, T. E. Kelly, F. T. Saulsbury, P. F. Chance, and H. D. Ochs. 2001. The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3. Nat. Genet. 27: 20-21.
-
(2001)
Nat. Genet
, vol.27
, pp. 20-21
-
-
Bennett, C.L.1
Christie, J.2
Ramsdell, F.3
Brunkow, M.E.4
Ferguson, P.J.5
Whitesell, L.6
Kelly, T.E.7
Saulsbury, F.T.8
Chance, P.F.9
Ochs, H.D.10
-
18
-
-
0035162560
-
Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse
-
Brunkow, M. E., E. W. Jeffery, K. A. Hjerrild, B. Paeper, L. B. Clark, S. A. Yasayko, J. E. Wilkinson, D. Galas, S. F. Ziegler, and F. Ramsdell. 2001: Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse. Nat. Genet. 27: 68-73.
-
(2001)
Nat. Genet
, vol.27
, pp. 68-73
-
-
Brunkow, M.E.1
Jeffery, E.W.2
Hjerrild, K.A.3
Paeper, B.4
Clark, L.B.5
Yasayko, S.A.6
Wilkinson, J.E.7
Galas, D.8
Ziegler, S.F.9
Ramsdell, F.10
-
19
-
-
33644841621
-
Attenuation of IL-7 receptor signaling is not required for allelic exclusion
-
Will, W. M., J. D. Aaker, M. A. Burchill, I. R. Harmon, J. J. O'Neil, C. A. Goetz, K. L. Hippen, and M. A. Farrar. 2006. Attenuation of IL-7 receptor signaling is not required for allelic exclusion. J. Immunol. 176: 3350-3355.
-
(2006)
J. Immunol
, vol.176
, pp. 3350-3355
-
-
Will, W.M.1
Aaker, J.D.2
Burchill, M.A.3
Harmon, I.R.4
O'Neil, J.J.5
Goetz, C.A.6
Hippen, K.L.7
Farrar, M.A.8
-
20
-
-
0027236954
-
Production of high-liter helper-free retroviruses by transient transfection
-
Pear, W. S., G. P. Nolan, M. L. Scott, and D. Baltimore. 1993. Production of high-liter helper-free retroviruses by transient transfection. Proc. Natl. Acad. Sci. USA 90: 8392-8396.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 8392-8396
-
-
Pear, W.S.1
Nolan, G.P.2
Scott, M.L.3
Baltimore, D.4
-
21
-
-
20444365877
-
Restricted STAT5 activation dictates appropriate thymic B versus T cell lineage commitment
-
Goetz, C. A., I. R. Harmon, J. J. O'Neil, M. A. Burchill, T. M. Johanns, and M. A. Farrar. 2005. Restricted STAT5 activation dictates appropriate thymic B versus T cell lineage commitment. J. Immunol. 174: 7753-7763.
-
(2005)
J. Immunol
, vol.174
, pp. 7753-7763
-
-
Goetz, C.A.1
Harmon, I.R.2
O'Neil, J.J.3
Burchill, M.A.4
Johanns, T.M.5
Farrar, M.A.6
-
22
-
-
0028878330
-
Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor γ chain
-
DiSanto, J. P., W. Muller, D. Guy-Grand, A. Fischer, and K. Rajewsky. 1995. Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor γ chain. Proc. Natl. Acad. Sci. USA 92: 377-381.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 377-381
-
-
DiSanto, J.P.1
Muller, W.2
Guy-Grand, D.3
Fischer, A.4
Rajewsky, K.5
-
23
-
-
0031569097
-
The common γ-chain of cytokine receptors regulates intrathymic T cell development at multiple stages
-
He, Y. W., H. Nakajima, W. J. Leonard, B. Adkins, and T. R. Malek. 1997. The common γ-chain of cytokine receptors regulates intrathymic T cell development at multiple stages. J. Immunol. 158: 2592-2599.
-
(1997)
J. Immunol
, vol.158
, pp. 2592-2599
-
-
He, Y.W.1
Nakajima, H.2
Leonard, W.J.3
Adkins, B.4
Malek, T.R.5
-
24
-
-
0027988545
-
Early lymphocyte expansion is severely impaired in interleukin-7 receptor deficient mice
-
Peschon, J. J., P. J. Morrissey, K. I. Grabstein, F. J. Ramsdell, E. Maraskovsky, B. C. Gliniak, L. S. Park, S. F. Ziegler, D. E. Williams, C. B. Ware, et al. 1994. Early lymphocyte expansion is severely impaired in interleukin-7 receptor deficient mice. J. Exp. Med. 180: 1955-1960.
-
(1994)
J. Exp. Med
, vol.180
, pp. 1955-1960
-
-
Peschon, J.J.1
Morrissey, P.J.2
Grabstein, K.I.3
Ramsdell, F.J.4
Maraskovsky, E.5
Gliniak, B.C.6
Park, L.S.7
Ziegler, S.F.8
Williams, D.E.9
Ware, C.B.10
-
25
-
-
11144357191
-
+ regulatory T cells
-
+ regulatory T cells. J. Immunol. 172: 5287-5296.
-
(2004)
J. Immunol
, vol.172
, pp. 5287-5296
-
-
Bensinger, S.J.1
Walsh, P.T.2
Zhang, J.3
Carroll, M.4
Parsons, R.5
Rathmell, J.C.6
Thompson, C.B.7
Burchill, M.A.8
Farrar, M.A.9
Turka, L.A.10
-
26
-
-
10744228466
-
+ memory T cells
-
+ memory T cells. J. Immunol. 171: 5853-5864.
-
(2003)
J. Immunol
, vol.171
, pp. 5853-5864
-
-
Burchill, M.A.1
Goetz, C.A.2
Prlic, M.3
O'Neil, J.J.4
Harmon, I.R.5
Bensinger, S.J.6
Turka, L.A.7
Brennan, P.8
Jameson, S.C.9
Farrar, M.A.10
-
27
-
-
0242580058
-
Loss of tolerance and autoimmunity affecting multiple organs in STAT5A/5B-deficient mice
-
Snow, J. W., N. Abraham, M. C. Ma, B. G. Herndier, A. W. Pastuszak, and M. A. Goldsmith. 2003. Loss of tolerance and autoimmunity affecting multiple organs in STAT5A/5B-deficient mice. J. Immunol. 171: 5042-5050.
-
(2003)
J. Immunol
, vol.171
, pp. 5042-5050
-
-
Snow, J.W.1
Abraham, N.2
Ma, M.C.3
Herndier, B.G.4
Pastuszak, A.W.5
Goldsmith, M.A.6
-
28
-
-
4444268818
-
Inactivation of Stat5 in mouse mammary epithelieum during pregnancy reveals distinct functions in cell proliferation, survival, and differentiation
-
Cui, Y., G. Riedlinger, K. Miyoshi, W. Tang, C. Li, C. X. Deng, G. W. Robinson, and L. Hennighausen. 2004. Inactivation of Stat5 in mouse mammary epithelieum during pregnancy reveals distinct functions in cell proliferation, survival, and differentiation. Mol. Cell. Biol. 24: 8037-8047.
-
(2004)
Mol. Cell. Biol
, vol.24
, pp. 8037-8047
-
-
Cui, Y.1
Riedlinger, G.2
Miyoshi, K.3
Tang, W.4
Li, C.5
Deng, C.X.6
Robinson, G.W.7
Hennighausen, L.8
-
29
-
-
18244365863
-
A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival
-
Lee, P. P., D. R. Fitzpatrick, C. Beard, H. K. Jessup, S. Lehar, K. W. Makar, M. Perez-Melgosa, M. T. Sweetser, M. S. Schlissel, S. Nguyen, et al. 2001. A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival. Immunity 15: 763-774.
-
(2001)
Immunity
, vol.15
, pp. 763-774
-
-
Lee, P.P.1
Fitzpatrick, D.R.2
Beard, C.3
Jessup, H.K.4
Lehar, S.5
Makar, K.W.6
Perez-Melgosa, M.7
Sweetser, M.T.8
Schlissel, M.S.9
Nguyen, S.10
-
30
-
-
32244444750
-
Stat5a/b are essential for normal lymphoid development and differentiation
-
Yao, Z., Y. Cui, W. T. Watford, J. H. Bream, K. Yamaoka, B. D. Hissong, D. Li, S. K. Durum, Q. Jiang, A. Bhandoola, et al. 2006. Stat5a/b are essential for normal lymphoid development and differentiation. Proc. Natl. Acad. Sci. USA 103: 1000-1005.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 1000-1005
-
-
Yao, Z.1
Cui, Y.2
Watford, W.T.3
Bream, J.H.4
Yamaoka, K.5
Hissong, B.D.6
Li, D.7
Durum, S.K.8
Jiang, Q.9
Bhandoola, A.10
-
31
-
-
1842477169
-
STAT5 activation underlies IL-7 receptor-dependent B cell development
-
Goetz, C. A., I. R. Harmon, J. J. O'Neil, M. A. Burchill, and M. A. Farrar. 2004. STAT5 activation underlies IL-7 receptor-dependent B cell development. J. Immunol. 172: 4770-4778.
-
(2004)
J. Immunol
, vol.172
, pp. 4770-4778
-
-
Goetz, C.A.1
Harmon, I.R.2
O'Neil, J.J.3
Burchill, M.A.4
Farrar, M.A.5
-
32
-
-
0026099588
-
Developmental regulation of lck gene expression in T lymphocytes
-
Wildin, R. S., A. M. Garvin, S. Pawar, D. B. Lewis, K. M. Abraham, K. A. Forbush, S. F. Ziegler, J. M. Allen, and R. M. Perlmutter. 1991. Developmental regulation of lck gene expression in T lymphocytes. J. Exp. Med. 173: 383-393.
-
(1991)
J. Exp. Med
, vol.173
, pp. 383-393
-
-
Wildin, R.S.1
Garvin, A.M.2
Pawar, S.3
Lewis, D.B.4
Abraham, K.M.5
Forbush, K.A.6
Ziegler, S.F.7
Allen, J.M.8
Perlmutter, R.M.9
-
33
-
-
15244354286
-
Regulatory T cell lineage specification by the forkhead transcription factor foxp3
-
Fontenot, J. D., J. P. Rasmussen, L. M. Williams, J. L. Dooley, A. G. Farr, and A. Y. Rudensky. 2005. Regulatory T cell lineage specification by the forkhead transcription factor foxp3. Immunity 22: 329-341.
-
(2005)
Immunity
, vol.22
, pp. 329-341
-
-
Fontenot, J.D.1
Rasmussen, J.P.2
Williams, L.M.3
Dooley, J.L.4
Farr, A.G.5
Rudensky, A.Y.6
-
34
-
-
17044430217
-
Identifying Foxp3-expressing suppressor T cells with a bicistronic reporter
-
Wan, Y. Y., and R. A. Flavell. 2005. Identifying Foxp3-expressing suppressor T cells with a bicistronic reporter. Proc. Natl. Acad. Sci. USA 102: 5126-5131.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 5126-5131
-
-
Wan, Y.Y.1
Flavell, R.A.2
-
35
-
-
0037243278
-
Neonates support lymphopenia-induced proliferation
-
Min, B., R. McHugh, G. D. Sempowski, C. Mackall, G. Foucras, and W. E. Paul. 2003. Neonates support lymphopenia-induced proliferation. Immunity 18: 131-140.
-
(2003)
Immunity
, vol.18
, pp. 131-140
-
-
Min, B.1
McHugh, R.2
Sempowski, G.D.3
Mackall, C.4
Foucras, G.5
Paul, W.E.6
-
36
-
-
0347994964
-
+ T cells in neonatal mice allows the generation of long-lived natural memory T cells
-
+ T cells in neonatal mice allows the generation of long-lived natural memory T cells. J. Immunol. 172: 15-19.
-
(2004)
J. Immunol
, vol.172
, pp. 15-19
-
-
Schuler, T.1
Hammerling, G.J.2
Arnold, B.3
-
37
-
-
0033988447
-
DNA binding site selection of dimeric and tetrameric Stat5 proteins reveals a large repertoire of divergent tetrameric Stat5a binding sites
-
Soldaini, E., S. John, S. Moro, J. Bollenbacher, U. Schindler, and W. J. Leonard. 2000. DNA binding site selection of dimeric and tetrameric Stat5 proteins reveals a large repertoire of divergent tetrameric Stat5a binding sites. Mol. Cell. Biol. 20: 389-401.
-
(2000)
Mol. Cell. Biol
, vol.20
, pp. 389-401
-
-
Soldaini, E.1
John, S.2
Moro, S.3
Bollenbacher, J.4
Schindler, U.5
Leonard, W.J.6
-
38
-
-
33747801470
-
+ regulatory T cells through a STAT dependent mechanism and induces the expansion of these cells in vivo
-
+ regulatory T cells through a STAT dependent mechanism and induces the expansion of these cells in vivo. Blood 108: 1571-1579.
-
(2006)
Blood
, vol.108
, pp. 1571-1579
-
-
Zorn, E.1
Nelson, E.A.2
Mohseni, M.3
Porcheray, F.4
Kim, H.5
Litsa, D.6
Bellucci, R.7
Raderschall, E.8
Canning, C.9
Soiffer, R.J.10
|