메뉴 건너뛰기




Volumn 17, Issue 2, 2002, Pages 167-178

CD4 regulatory T cells prevent lethal autoimmunity in IL-2Rβ-deficient mice: Implications for the nonredundant function of IL-2

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR; RECEPTOR SUBUNIT;

EID: 0036669298     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-7613(02)00367-9     Document Type: Article
Times cited : (699)

References (33)
  • 3
    • 0035873070 scopus 로고    scopus 로고
    • A requirement for IL-2/IL-2 receptor signaling in intrathymic negative selection
    • Bassiri H., Carding S.R. A requirement for IL-2/IL-2 receptor signaling in intrathymic negative selection. J. Immunol. 166:2001;5945-5954.
    • (2001) J. Immunol. , vol.166 , pp. 5945-5954
    • Bassiri, H.1    Carding, S.R.2
  • 4
    • 0028135419 scopus 로고
    • Induction of interleukin 2 receptor β chain expression by self-recognition in the thymus
    • Hanke T., Mitnacht R., Boyd R., Hünig T. Induction of interleukin 2 receptor β chain expression by self-recognition in the thymus. J. Exp. Med. 180:1994;1629-1636.
    • (1994) J. Exp. Med. , vol.180 , pp. 1629-1636
    • Hanke, T.1    Mitnacht, R.2    Boyd, R.3    Hünig, T.4
  • 5
    • 0028980744 scopus 로고
    • Expression and function of the γc subunit of the IL2, IL-4, and IL-7 receptors. Distinct interaction of γc in the IL-4 receptor
    • He Y.-W., Adkins B., Furse R.K., Malek T.R. Expression and function of the γc subunit of the IL2, IL-4, and IL-7 receptors. Distinct interaction of γc in the IL-4 receptor. J. Immunol. 154:1995;1596-1605.
    • (1995) J. Immunol. , vol.154 , pp. 1596-1605
    • He, Y.-W.1    Adkins, B.2    Furse, R.K.3    Malek, T.R.4
  • 6
    • 0031788725 scopus 로고    scopus 로고
    • The structure and function of γc-dependent cytokines and receptors: Regulation of T lymphocyte development and homeostasis
    • He Y.-W., Malek T.R. The structure and function of γc-dependent cytokines and receptors. regulation of T lymphocyte development and homeostasis Crit. Rev. Immunol. 18:1998;503-524.
    • (1998) Crit. Rev. Immunol. , vol.18 , pp. 503-524
    • He, Y.-W.1    Malek, T.R.2
  • 7
    • 0025898690 scopus 로고
    • Superantigens: Mechanism of T-cell stimulation and role in immune responses
    • Herman A., Kappler J.W., Marrack P., Pullen A.M. Superantigens. mechanism of T-cell stimulation and role in immune responses Annu. Rev. Immunol. 9:1991;745-772.
    • (1991) Annu. Rev. Immunol. , vol.9 , pp. 745-772
    • Herman, A.1    Kappler, J.W.2    Marrack, P.3    Pullen, A.M.4
  • 10
    • 0029118133 scopus 로고
    • Normal clonal expansion but impaired Fas-mediated cell death and anergy induction in interleukin-2-deficient mice
    • Kneitz B., Herrmann T., Yonehara S., Schimpl A. Normal clonal expansion but impaired Fas-mediated cell death and anergy induction in interleukin-2-deficient mice. Eur. J. Immunol. 25:1995;2572-2577.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 2572-2577
    • Kneitz, B.1    Herrmann, T.2    Yonehara, S.3    Schimpl, A.4
  • 11
    • 0028142358 scopus 로고
    • Thymic selection and peptide-induced activation of T cell receptor-transgenic CD8 T cells in interleukin-2-deficient mice
    • Krämer S., Mamalaki C., Schimpl A., Kioussis D., Hünig T. Thymic selection and peptide-induced activation of T cell receptor-transgenic CD8 T cells in interleukin-2-deficient mice. Eur. J. Immunol. 24:1994;2317-2322.
    • (1994) Eur. J. Immunol. , vol.24 , pp. 2317-2322
    • Krämer, S.1    Mamalaki, C.2    Schimpl, A.3    Kioussis, D.4    Hünig, T.5
  • 12
    • 0026017971 scopus 로고
    • Interleukin-2 programs αβ T lymphocytes for apoptosis
    • Lenardo M.J. Interleukin-2 programs αβ T lymphocytes for apoptosis. Nature. 353:1991;858-861.
    • (1991) Nature , vol.353 , pp. 858-861
    • Lenardo, M.J.1
  • 13
    • 0011040712 scopus 로고
    • Identification and initial characterization of a rat monoclonal antibody reactive with the murine interleukin 2 receptor-ligand complex
    • Malek T.R., Robb R.J., Shevach E.M. Identification and initial characterization of a rat monoclonal antibody reactive with the murine interleukin 2 receptor-ligand complex. Proc. Natl. Acad. Sci. USA. 80:1983;5694-5698.
    • (1983) Proc. Natl. Acad. Sci. USA , vol.80 , pp. 5694-5698
    • Malek, T.R.1    Robb, R.J.2    Shevach, E.M.3
  • 14
    • 0034654319 scopus 로고    scopus 로고
    • Normal lymphoid homeostasis and lack of lethal autoimmunity in mice containing mature T cells with severely impaired IL-2 receptors
    • Malek T.R., Porter B.O., Codias E.K., Scibelli P., Yu A. Normal lymphoid homeostasis and lack of lethal autoimmunity in mice containing mature T cells with severely impaired IL-2 receptors. J. Immunol. 164:2000;2905-2914.
    • (2000) J. Immunol. , vol.164 , pp. 2905-2914
    • Malek, T.R.1    Porter, B.O.2    Codias, E.K.3    Scibelli, P.4    Yu, A.5
  • 15
    • 0035253708 scopus 로고    scopus 로고
    • Broad programming by IL-2 receptor signaling for extended growth to multiple cytokines and functional maturation of antigen-activated T cells
    • Malek T.R., Yu A., Scibelli P., Lichtenheld M.G., Codias E.K. Broad programming by IL-2 receptor signaling for extended growth to multiple cytokines and functional maturation of antigen-activated T cells. J. Immunol. 166:2001;1675-1683.
    • (2001) J. Immunol. , vol.166 , pp. 1675-1683
    • Malek, T.R.1    Yu, A.2    Scibelli, P.3    Lichtenheld, M.G.4    Codias, E.K.5
  • 16
    • 0033491981 scopus 로고    scopus 로고
    • Biology of the interleukin-2 receptor
    • Nelson B.H., Willerford D.M. Biology of the interleukin-2 receptor. Adv. Immunol. 70:1998;1-81.
    • (1998) Adv. Immunol. , vol.70 , pp. 1-81
    • Nelson, B.H.1    Willerford, D.M.2
  • 17
    • 7144259082 scopus 로고    scopus 로고
    • Regulatory CD4 T cells: Expression of IL-2Rα chain, resistance to clonal deletion and IL-2 dependency
    • Papiernik M., de Moraes M.L., Pontoux C., Vasseur F., Penit C. Regulatory CD4 T cells. expression of IL-2Rα chain, resistance to clonal deletion and IL-2 dependency Int. Immunol. 10:1997;371-378.
    • (1997) Int. Immunol. , vol.10 , pp. 371-378
    • Papiernik, M.1    De Moraes, M.L.2    Pontoux, C.3    Vasseur, F.4    Penit, C.5
  • 18
    • 0027369395 scopus 로고
    • Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene
    • Sadlack B., Merz H., Schorle H., Schimpl A., Feller A.C., Horak I. Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene. Cell. 75:1993;253-261.
    • (1993) Cell , vol.75 , pp. 253-261
    • Sadlack, B.1    Merz, H.2    Schorle, H.3    Schimpl, A.4    Feller, A.C.5    Horak, I.6
  • 20
    • 0034716925 scopus 로고    scopus 로고
    • Regulatory T cells: Key controllers of immunologic self-tolerance
    • Sakaguchi S. Regulatory T cells. key controllers of immunologic self-tolerance Cell. 101:2000;455-458.
    • (2000) Cell , vol.101 , pp. 455-458
    • Sakaguchi, S.1
  • 22
    • 0025899598 scopus 로고
    • Development and function of T cells in mice rendered interleukin-2 deficient by gene targeting
    • Schorle H., Holtschke T., Hunig T., Shimpl A., Horak I. Development and function of T cells in mice rendered interleukin-2 deficient by gene targeting. Nature. 352:1991;621-624.
    • (1991) Nature , vol.352 , pp. 621-624
    • Schorle, H.1    Holtschke, T.2    Hunig, T.3    Shimpl, A.4    Horak, I.5
  • 23
    • 0034084162 scopus 로고    scopus 로고
    • Regulatory T cells in autoimmunity
    • Shevach E.M. Regulatory T cells in autoimmunity. Annu. Rev. Immunol. 18:2000;423-449.
    • (2000) Annu. Rev. Immunol. , vol.18 , pp. 423-449
    • Shevach, E.M.1
  • 26
    • 0030861424 scopus 로고    scopus 로고
    • Normal thymic selection, superantigen-induced deletion and Fas-mediated apoptosis of T cells in IL-2 receptor β-chain deficient mice
    • Suzuki H., Hayakawa A., Bouchard D., Nakashima I., Mak T.W. Normal thymic selection, superantigen-induced deletion and Fas-mediated apoptosis of T cells in IL-2 receptor β-chain deficient mice. Int. Immunol. 9:1997;1367-1374.
    • (1997) Int. Immunol. , vol.9 , pp. 1367-1374
    • Suzuki, H.1    Hayakawa, A.2    Bouchard, D.3    Nakashima, I.4    Mak, T.W.5
  • 27
    • 0342632839 scopus 로고    scopus 로고
    • Normal regulatory alpha/beta T cells effectively eliminate abnormally activated T cells lacking the interleukin 2 receptor beta in vivo
    • Suzuki H., Zhou Y.W., Kato M., Mak T.W., Nakashima I. Normal regulatory alpha/beta T cells effectively eliminate abnormally activated T cells lacking the interleukin 2 receptor beta in vivo. J. Exp. Med. 190:1999;1561-1572.
    • (1999) J. Exp. Med. , vol.190 , pp. 1561-1572
    • Suzuki, H.1    Zhou, Y.W.2    Kato, M.3    Mak, T.W.4    Nakashima, I.5
  • 28
    • 0033985780 scopus 로고    scopus 로고
    • + immunoregulatory T cells is antigen nonspecific
    • + immunoregulatory T cells is antigen nonspecific. J. Immunol. 164:2000;183-190.
    • (2000) J. Immunol. , vol.164 , pp. 183-190
    • Thornton, A.M.1    Shevach, E.M.2
  • 29
    • 0032502801 scopus 로고    scopus 로고
    • Homeostasis and self-tolerance in the immune system: Turning lymphocytes off
    • Van Parijs L., Abbas A.K. Homeostasis and self-tolerance in the immune system. turning lymphocytes off Science. 280:1998;243-248.
    • (1998) Science , vol.280 , pp. 243-248
    • Van Parijs, L.1    Abbas, A.K.2
  • 30
    • 0031569514 scopus 로고    scopus 로고
    • Functional responses and apoptosis of CD25 (IL-2Rα)-deficient T cells expressing a transgenic antigen receptor
    • Van Parijs L., Biuckians A., Ibragimov A., Alt F.W., Willerford D.M., Abbas A.K. Functional responses and apoptosis of CD25 (IL-2Rα)-deficient T cells expressing a transgenic antigen receptor. J. Immunol. 158:1997;3738-3745.
    • (1997) J. Immunol. , vol.158 , pp. 3738-3745
    • Van Parijs, L.1    Biuckians, A.2    Ibragimov, A.3    Alt, F.W.4    Willerford, D.M.5    Abbas, A.K.6
  • 31
    • 0028784289 scopus 로고
    • Interleukin-2 receptor α chain regulates the size and content of the peripheral lymphoid compartment
    • Willerford D.M., Chen J., Ferry J.A., Davidson L., Ma A., Alt F.W. Interleukin-2 receptor α chain regulates the size and content of the peripheral lymphoid compartment. Immunity. 3:1995;521-530.
    • (1995) Immunity , vol.3 , pp. 521-530
    • Willerford, D.M.1    Chen, J.2    Ferry, J.A.3    Davidson, L.4    Ma, A.5    Alt, F.W.6
  • 32
    • 0034965185 scopus 로고    scopus 로고
    • Control of T cell hyperactivation in IL-2-deficient mice by CD4(+)CD25(-) and CD4(+)CD25(+) T cells: Evidence for two distinct regulatory mechanisms
    • Wolf M., Schimpl A., Hunig T. Control of T cell hyperactivation in IL-2-deficient mice by CD4(+)CD25(-) and CD4(+)CD25(+) T cells. evidence for two distinct regulatory mechanisms Eur. J. Immunol. 31:2001;1637-1645.
    • (2001) Eur. J. Immunol. , vol.31 , pp. 1637-1645
    • Wolf, M.1    Schimpl, A.2    Hunig, T.3
  • 33
    • 0032449386 scopus 로고    scopus 로고
    • Spontaneous expression of interleukin-2 in vivo in specific tissues of young mice
    • Yang-Snyder J.A., Rothenberg E.V. Spontaneous expression of interleukin-2 in vivo in specific tissues of young mice. Dev. Immunol. 5:1998;223-245.
    • (1998) Dev. Immunol. , vol.5 , pp. 223-245
    • Yang-Snyder, J.A.1    Rothenberg, E.V.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.