-
1
-
-
0032964644
-
Transforming growth factor betas and their signaling receptors in human hepatocellular carcinoma
-
(1999)
Am J Surg
, vol.177
, pp. 209-215
-
-
Abou-Shady, M.1
Baer, H.U.2
Friess, H.3
Berberat, P.4
Zimmermann, A.5
Graber, H.6
Gold, L.I.7
Korc, M.8
Buchler, M.W.9
-
2
-
-
0033971619
-
Alternative splicing within the TGF-beta type I receptor gene (ALK-5) generates two major functional isoforms in vascular smooth muscle cells
-
(2000)
FEBS Lett
, vol.467
, pp. 128-132
-
-
Agrotis, A.1
Condron, M.2
Bobik, A.3
-
9
-
-
0031415228
-
Transforming growth factor-beta isoform expression in human ovarian tumours
-
(1997)
Eur J Cancer
, vol.33
, pp. 2397-2403
-
-
Bartlett, J.M.1
Langdon, S.P.2
Scott, W.N.3
Love, S.B.4
Miller, E.P.5
Katsaros, D.6
Smyth, J.F.7
Miller, W.R.8
-
10
-
-
0032900109
-
Higher frequency of DPC4/Smad4 alterations in pancreatic cancer cell lines than in primary pancreatic adenocarcinomas
-
(1999)
Cancer Lett
, vol.139
, pp. 43-49
-
-
Bartsch, D.1
Barth, P.2
Bastian, D.3
Ramaswamy, A.4
Gerdes, B.5
Chaloupka, B.6
Deiss, Y.7
Simon, B.8
Schudy, A.9
-
11
-
-
0033535531
-
Mutations of the DPC4/Smad4 gene in neuroendocrine pancreatic tumors
-
(1999)
Oncogene
, vol.18
, pp. 2367-2371
-
-
Bartsch, D.1
Hahn, S.A.2
Danichevski, K.D.3
Ramaswamy, A.4
Bastian, D.5
Galehdari, H.6
Barth, P.7
Schmiegel, W.8
Simon, B.9
Rothmund, M.10
-
12
-
-
0032770957
-
Tumor-associated transforming growth factor-beta and interleukin-10 contribute to a systemic Th2 immune phenotype in pancreatic carcinoma patients
-
(1999)
Am J Pathol
, vol.155
, pp. 537-547
-
-
Bellone, G.1
Turletti, A.2
Artusio, E.3
Mareschi, K.4
Carbone, A.5
Tibaudi, D.6
Robecchi, A.7
Emanuelli, G.8
Rodeck, U.9
-
13
-
-
0032775701
-
Screening Smad1, Smad2, Smad3, and Smad5 for germline mutations in juvenile polyposis syndrome
-
(1999)
Gut
, vol.45
, pp. 406-408
-
-
Bevan, S.1
Woodford-Richens, K.2
Rozen, P.3
Eng, C.4
Young, J.5
Dunlop, M.6
Neale, K.7
Phillips, R.8
Markie, D.9
Rodriguez-Bigas, M.10
Leggett, B.11
Sheridan, E.12
Hodgson, S.13
Iwama, T.14
Eccles, D.15
Bodmer, W.16
Houlston, R.17
Tomlinson, I.18
-
18
-
-
0031764556
-
Microsatellite alterations and p53, TGF-beta-RII, IGFIIR and bax mutations in sporadic nonsmall-cell lung cancer
-
(1998)
Int J Cancer
, vol.78
, pp. 606-609
-
-
Caligo, M.A.1
Ghimenti, C.2
Marchetti, A.3
Lonobile, A.4
Buttitta, F.5
Pellegrini, S.6
Bevilacqua, G.7
-
19
-
-
0033946516
-
Genetic progression in microsatellite instability high (MSI-H) colon cancers correlates with clinico-pathological parameters: A study of the TGF beta RII, BAX, HMSH3, HMSH6, IGFIIR and BLM genes
-
(2000)
Int J Cancer
, vol.89
, pp. 230-235
-
-
Calin, G.A.1
Gafa, R.2
Tibiletti, M.G.3
Herlea, V.4
Becheanu, G.5
Cavazzini, L.6
Barbanti-Brodano, G.7
Nenci, I.8
Negrini, M.9
Lanza, G.10
-
20
-
-
0033585086
-
Smad4/DPC4 silencing and hyper-active Ras jointly disrupt transforming growth factor-beta antiproliferative responses in colon cancer cells
-
(1999)
J Bio Chem
, vol.274
, Issue.19
, pp. 33637-33643
-
-
Calonge, M.J.1
Massague, J.2
-
23
-
-
0023652332
-
The transforming growth factor-beta system, a complex pattern of cross-reactive ligands and receptors
-
(1987)
Cell
, vol.48
, pp. 409-415
-
-
Cheifetz, S.1
Weatherbee, J.A.2
Tsang, M.L.3
Anderson, J.K.4
Mole, J.E.5
Lucas, R.6
Massague, J.7
-
26
-
-
0033516627
-
Structural alterations of transforming growth factor-beta receptor genes in human cervical carcinoma
-
(1999)
Int J Cancer
, vol.82
, pp. 43-51
-
-
Chen, T.P.1
De Vries, E.G.E.2
Hollema, H.3
Yegen, H.A.4
Vellucci, V.F.5
Strickler, H.D.6
Hildesheim, A.7
Reiss, M.8
-
27
-
-
0029821872
-
Microsatellite alterations in plasma DNA of small cell lung cancer patients
-
(1996)
Nature Med
, vol.2
, pp. 1033-1035
-
-
Chen, X.Q.1
Stroun, M.2
Magnenat, J.L.3
Nicod, L.P.4
Kurt, A.M.5
Lyautey, J.6
Lederrey, C.7
Anker, P.8
-
36
-
-
12344320716
-
Thrombospondin-1 is a major activator of TGF-beta-1 in vivo
-
(1998)
Cell
, vol.93
, pp. 1159-1170
-
-
Crawford, S.E.1
Stellmach, V.2
Murphyullrich, J.E.3
Ribeiro, S.F.4
Lawler, J.5
Hynes, R.O.6
Boivin, G.P.7
Bouck, N.8
-
37
-
-
0030598681
-
TGF-beta-1 inhibits the formation of benign skin tumors, but enhances progression to invasive spindle carcinomas in transgenic mice
-
(1996)
Cell
, vol.86
, pp. 531-542
-
-
Cui, W.1
Fowlis, D.J.2
Bryson, S.3
Duffle, E.4
Ireland, H.5
Balmain, A.6
Akhurst, R.J.7
-
44
-
-
0031472520
-
Comparison of the effects of acsdkp, thymosin beta-4, macrophage inflammatory protein 1-alpha and transforming growth factor beta on human leukemic cells
-
(1997)
Leukemia and Lymphoma
, vol.27
, pp. 487-494
-
-
Defard, M.1
Lemoine, F.M.2
Bonnet, M.L.3
Baillou, C.4
Isnard, F.5
Najman, A.6
Guigon, M.7
-
46
-
-
0031575532
-
Hpv16 E6 oncoprotein stimulates the transforming growth factor-beta-1 promoter in fibroblasts through a specific GC-rich sequence
-
(1997)
Virology
, vol.228
, pp. 190-199
-
-
Dey, A.1
Atcha, I.A.2
Bagchi, S.3
-
50
-
-
0034075926
-
Expression of transforming growth factor beta-1 in gastric cancer and in the gastric mucosa of first-degree relatives of patients with gastric cancer
-
(2000)
Br J Cancer
, vol.82
, pp. 1795-1800
-
-
Ebert, M.P.A.1
Yu, J.2
Miehlke, S.3
Fei, G.4
Lendeckel, U.5
Ridwelski, K.6
Stolte, M.7
Bayerdorffer, E.8
Malfertheiner, P.9
-
53
-
-
0033168833
-
Transforming growth factor-beta type II receptor confers tumor suppressor activity in murine renal carcinoma (RENCA) cells
-
(1999)
Urology
, vol.54
, pp. 164-170
-
-
Engel, J.D.1
Kundu, S.D.2
Yang, T.3
Yang, S.4
Goodwin, S.5
Janulis, L.6
Cho, J.S.7
Chang, J.8
Kim, S.J.9
Lee, C.10
-
59
-
-
0032771825
-
Frequent 4-bp deletion in exon 9 of the SMAD4/MADH4 gene in familial juvenile polyposis patients
-
(1999)
Genes, Chromosomes Cancer
, vol.25
, pp. 403-406
-
-
Friedl, W.1
Kruse, R.2
Uhlhaas, S.3
Stolte, M.4
Schartmann, B.5
Keller, K.M.6
Jungck, M.7
Stern, M.8
Loff, S.9
Back, W.10
Propping, P.11
Jenne, D.E.12
-
61
-
-
0032968104
-
Gene mutation of transforming growth factor beta I type II receptor in hepatocellular carcinoma
-
(1999)
Int J Cancer
, vol.81
, pp. 851-853
-
-
Furuta, K.1
Misao, S.2
Takahashi, K.3
Tagaya, T.4
Fukuzawa, Y.5
Ishikawa, T.6
Yoshioka, K.7
Kakumu, S.8
-
65
-
-
0033564547
-
Blocking transforming growth factor beta signaling in transgenic epidermis accelerates chemical carcinogenesis: A mechanism associated with increased angiogenesis
-
(1999)
Cancer Res
, vol.59
, pp. 2861-2868
-
-
Go, C.1
Li, P.2
Wang, X.J.3
-
67
-
-
0032587431
-
Frameshift mutations in TGF beta RII, IGFIIR, BAX, hMSH3 and hMSH6 are absent in lung cancers
-
(1999)
Carcinogenesis
, vol.20
, pp. 499-502
-
-
Gotoh, K.1
Yatabe, Y.2
Sugiura, T.3
Takagi, K.4
Ogawa, M.5
Takahashi, T.6
Mitsudomi, T.7
-
68
-
-
0033555627
-
Mutational inactivation of transforming growth factor beta receptor type II in microsatellite stable colon cancers
-
(1999)
Cancer Res
, vol.59
, pp. 320-324
-
-
Grady, W.M.1
Myeroff, L.L.2
Swinler, S.E.3
Rajput, A.4
Thiagalingam, S.5
Lutterbaugh, J.D.6
Neumann, A.7
Brattain, M.G.8
Chang, J.9
Kim, S.J.10
Kinzler, K.W.11
Vogelstein, B.12
Willson, J.V.13
Markowitz, S.14
-
69
-
-
0034642605
-
Tumor microsatellite instability and clinical outcome in young patients with colorectal cancer
-
(2000)
New Eng J Med
, vol.342
, pp. 69-77
-
-
Gryfe, R.1
Kim, H.2
Hsieh, E.T.K.3
Aronson, M.D.4
Holowaty, E.J.5
Bull, S.B.6
Redston, M.7
Gallinger, S.8
-
70
-
-
0031658101
-
Analyses of mutation and loss of heterozygosity of coding sequences of the entire transforming growth factor beta type ii receptor gene in sporadic human gastric cancer
-
(1998)
Carcinogenesis
, vol.19
, pp. 1539-1544
-
-
Guo, R.J.1
Wang, Y.2
Kaneko, E.3
Wang, D.Y.4
Arai, H.5
Hanai, H.6
Takenoshita, S.7
Hagiwara, K.8
Harris, C.C.9
Sugimura, H.10
-
72
-
-
0032848660
-
Repression of the gene encoding the TGFbeta type II receptor is a major target of the EWS-FLI1 oncoprotein
-
(1999)
Nature Gen
, vol.23
, pp. 222-227
-
-
Hahm, K.B.1
Cho, K.N.2
Lee, C.3
Im, Y.H.4
Chang, J.5
Choi, S.G.6
Sorensen, P.H.B.7
Thiele, C.J.8
Kim, S.J.9
-
73
-
-
0032520915
-
Mutations of the dpc4/smad4 gene in biliary tract carcinoma
-
(1998)
Cancer Res
, vol.58
, pp. 1124-1126
-
-
Hahn, S.A.1
Bartsch, D.2
Schroers, A.3
Galehdari, H.4
Becker, M.5
Ramaswamy, A.6
Schwartewaldhoff, I.7
Maschek, H.8
Schmiegel, W.9
-
76
-
-
0031587828
-
The mad-related protein smad7 associates with the TGF-beta receptor and functions as an antagonist of TGF-beta signaling
-
(1997)
Cell
, vol.89
, pp. 1165-1173
-
-
Hayashi, H.1
Abdollah, S.2
Qiu, Y.B.3
Cai, J.X.4
Xu, Y.Y.5
Grinnell, B.W.6
Richardson, M.A.7
Topper, J.N.8
Gimbrone, M.A.9
Wrana, J.L.10
Falb, D.11
-
80
-
-
0032524069
-
Mutations in the smad4/dpc4 gene in juvenile polyposis
-
(1998)
Science
, vol.280
, pp. 1086-1088
-
-
Howe, J.R.1
Roth, S.2
Ringold, J.C.3
Summers, R.W.4
Jarvinen, H.J.5
Sistonen, P.6
Tomlinson, I.M.7
Houlston, R.S.8
Bevan, S.9
Mitros, F.A.10
Stone, E.M.11
Aaltonen, L.A.12
-
88
-
-
0033625354
-
Resistance to TGF-beta 1 correlates with a reduction of TGF-beta type II receptor expression in Burkitt's lymphoma and Epstein-Barr virus-transformed B lymphoblastoid cell lines
-
(2000)
J General Virol
, vol.81
, pp. 1567-1578
-
-
Inman, G.J.1
Allday, M.J.2
-
93
-
-
0000031048
-
Transcriptional repression of the transforming growth factor-beta type I receptor gene by DNA methylation results in the development of TGF-beta resistance in human gastric cancer
-
(1999)
Oncogene
, vol.18
, pp. 7280-7286
-
-
Kang, S.H.1
Bang, Y.J.2
Im, Y.H.3
Yang, H.K.4
Lee, D.A.5
Lee, H.Y.6
Lee, H.S.7
Kim, N.K.8
Kim, S.J.9
-
95
-
-
0032585977
-
Cytokine expression of transforming growth factor-beta 2 and interleukin-10 in squamous cell carcinomas of the head and neck. Comparison of tissue expression and serum levels
-
(1999)
HNO
, vol.47
, pp. 879-884
-
-
Karcher, J.1
Reisser, C.2
Daniel, V.3
Herold-Mende, C.4
-
97
-
-
0005509268
-
Accumulated frameshift mutations at coding nucleotide repeats during the progression of gastric carcinoma with microsatellite instability
-
(1999)
Lab Invest
, vol.79
, pp. 1113-1120
-
-
Kim, J.J.1
Back, M.J.2
Kim, L.3
Kim, N.G.4
Lee, Y.C.5
Song, S.Y.6
Noh, S.H.7
Kim, H.8
-
98
-
-
0000799313
-
Dpc4, a candidate tumor suppressor gene, is altered infrequently in head and neck squamous cell carcinoma
-
(1996)
Cancer Res
, vol.56
, pp. 2519-2521
-
-
Kim, S.K.1
Fan, Y.2
Papadimitrakopoulou, V.3
Clayman, G.4
Hittelman, W.N.5
Hong, W.K.6
Lotan, R.7
Mao, L.8
-
99
-
-
0032897720
-
Reduced transforming growth factor-beta type II receptor (TGF-beta RII) expression in adenocarcinoma of the lung
-
(1999)
Anticancer Res
, vol.19
, pp. 301-306
-
-
Kim, W.S.1
Park, C.2
Jung, Y.S.3
Kim, H.S.4
Han, J.H.5
Park, C.H.6
Kim, K.7
Kim, J.8
Shim, Y.M.9
Park, K.10
-
100
-
-
0032849994
-
Overexpression of Smad2 and colocalization with TGF-beta(1) in human pancreatic cancer
-
(1999)
Digestive Diseases Sci
, vol.44
, pp. 1793-1802
-
-
Kleeff, J.1
Friess, H.2
Simon, P.3
Susmallian, S.4
Buchler, P.5
Zimmermann, A.6
Buchler, M.W.7
Korc, M.8
-
101
-
-
0033598408
-
The TGF-beta signaling inhibitor Smad7 enhances tumorigenicity in pancreatic cancer
-
(1999)
Oncogene
, vol.18
, pp. 5363-5372
-
-
Kleef, J.1
Ishiwata, T.2
Maruyama, H.3
Friess, H.4
Truong, P.5
Buchler, M.W.6
Falb, D.7
Korc, M.8
-
102
-
-
0030965611
-
Processing of the transforming growth factor beta type I and II receptors - Biosynthesis and ligand-induced regulation
-
(1997)
J Biol Chem
, vol.272
, pp. 6423-6427
-
-
Koli, K.M.1
Arteaga, C.L.2
-
110
-
-
0141974555
-
Absence of expression of transforming growth factor-beta type II receptor is associated with an aggressive growth pattern in a murine renal carcinoma cell line, renca
-
(1998)
J Urol
, vol.160
, pp. 1883-1888
-
-
Kundu, S.D.1
Kim, I.Y.2
Zelner, D.3
Janulis, L.4
Goodwin, S.5
Engel, J.D.6
Lee, C.7
-
118
-
-
0033612141
-
Defective angiogenesis in mice lacking endogiin
-
(1999)
Science
, vol.284
, pp. 1534-1537
-
-
Li, D.Y.1
Sorensen, L.K.2
Brooke, B.S.3
Urness, L.D.4
Davis, E.C.5
Taylor, D.G.6
Boak, B.B.7
Wendal, D.P.8
-
128
-
-
0029066689
-
Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability
-
(1995)
Science
, vol.268
, pp. 1336-1338
-
-
Markowitz, S.1
Wang, J.2
Myeroff, L.3
Parsons, R.4
Sun, L.5
Lutterbaugh, J.6
Fan, R.S.7
Zborowska, E.8
Kinzler, K.W.9
Vogeistein, B.10
-
132
-
-
0027200338
-
Biologic characteristics of acute leukemia after myelodysplastic syndrome
-
(1993)
Blood
, vol.81
, pp. 3388-3394
-
-
Masuya, M.1
Kita, K.2
Shimizu, N.3
Ohishi, K.4
Katayama, N.5
Sekine, T.6
Otsuji, A.7
Miwa, H.8
Shirakawa, S.9
-
133
-
-
0028171579
-
Endoglin, a TGF-beta binding protein of endothelial cells, is the gene for hereditary haemorrhagic telangiectasia type 1
-
(1994)
Nature Gen
, vol.8
, pp. 345-351
-
-
McAllister, K.A.1
Grogg, K.M.2
Johnson, D.W.3
Gallione, C.J.4
Baldwin, M.A.5
Jackson, C.E.6
Helmbald, E.A.7
Markel, D.S.8
McKinnon, W.C.9
Murrell, J.10
-
135
-
-
0033587156
-
Higher frequency of Smad4 gene mutation in humar colorectal cancer with distant metastasis
-
(1999)
Oncogene
, vol.20
, Issue.18
, pp. 3098-3103
-
-
Miyaki, M.1
Iijima, T.2
Konishi, M.3
Sakai, K.4
Ishii, A.5
Yasuno, M.6
Hishima, T.7
Koike, M.8
Shitara, N.9
Iwama, T.10
Utsunomiya, J.11
Kuroki, T.12
Mori, T.13
-
137
-
-
0030938595
-
Genomic sequencing of dpc4 in the analysis of familial pancreatic carcinoma
-
(1997)
Diagnostic Mol Pathol
, vol.6
, pp. 85-90
-
-
Moskaluk, C.A.1
Hruban, R.H.2
Schutte, M.3
Lietman, A.S.4
Smyrk, T.5
Fusaro, L.6
Fusaro, R.7
Lynch, J.8
Yeo, C.J.9
Jackson, C.E.10
Lynch, H.T.11
Kern, S.E.12
-
138
-
-
0033524949
-
The integrin alpha v beta 6 binds and activates latent TGF beta 1: A mechanism for regulating pulmonary inflammation and fibrosis
-
(1999)
Cell
, vol.96
, pp. 319-328
-
-
Munger, J.S.1
Huang, X.Z.2
Kawakatsu, H.3
Griffiths, M.D.4
Dalton, S.L.5
Wu, J.F.6
Pittet, J.F.7
Kaminski, N.8
Garat, C.9
Matthay, M.A.10
Rifkin, D.B.11
Sheppard, D.12
-
139
-
-
18744424592
-
Molecular and biological analysis of carcinoma of the small intestine: Beta-catenin gene mutation by interstitial deletion involving exon 3 and replication error phenotype
-
(2000)
Am J Gastroenterol
, vol.95
, pp. 1576-1580
-
-
Murata, M.1
Iwao, K.2
Miyoshi, Y.3
Nagasawa, Y.4
Ohta, T.5
Shibata, K.6
Oda, K.7
Wada, H.8
Tominaga, S.9
Matsuda, Y.10
Ohsawa, M.11
Nakamura, Y.12
Shimano, T.13
-
142
-
-
0028785602
-
A transforming growth factor beta receptor type II gene mutation common in colon and gastric but rare in endometrial cancers with microsatellite instability
-
(1995)
Cancer Res
, vol.55
, pp. 5545-5547
-
-
Myeroff, L.L.1
Parsons, R.2
Kim, S.J.3
Hedrick, L.4
Cho, K.R.5
Orth, K.6
Mathis, M.7
Kinzler, K.W.8
Lutterbaugh, J.9
Park, K.10
Bang, Y.J.11
Lee, H.Y.12
Park, J.G.13
Lynch, H.T.14
Roberts, A.B.15
Vogelstein, B.16
Markowitz, S.D.17
-
144
-
-
0030611757
-
Identification of smad7, a tgf-beta-inducible antagonist of TGF-beta signalling
-
(1997)
Nature
, vol.389
, pp. 631-635
-
-
Nakao, A.1
Afrakhte, M.2
Moren, A.3
Nakayama, T.4
Christian, J.L.5
Heuchel, R.6
Itoh, S.7
Kawabata, N.8
Heldin, N.E.9
Heldin, C.H.10
Tendijke, P.11
-
145
-
-
0026556208
-
Neutralizing antibodies against transforming growth factor beta potentiate the proliferation of ki-1 positive lymphoma cells. Further evidence for negative autocrine regulation by transforming growth factor beta
-
(1992)
Am J Pathol
, vol.140
, pp. 709-718
-
-
Newcom, S.R.1
Tagra, K.K.2
Kadin, M.E.3
-
151
-
-
10344227149
-
Mutations of the transforming growth factor beta type II receptor gene and microsatellite instability in gastric cancer
-
(1996)
Int J Cancer
, vol.68
, pp. 203-206
-
-
Ohue, M.1
Tomita, N.2
Monden, T.3
Miyoshi, Y.4
Ohnishi, T.5
Izawa, H.6
Kawabata, Y.7
Sasaki, M.8
Sekimoto, M.9
Nishisho, I.10
Shiozaki, H.11
Monden, M.12
-
154
-
-
0033016853
-
Analysis of microsatellite instabfiity in cervical cancer
-
(1999)
Int J Gynecol Cancer
, vol.9
, pp. 67-71
-
-
Ou, C.Y.1
Chang, J.G.2
Tseng, H.H.3
Wei, H.J.4
Su, T.H.5
Hsu, T.Y.6
Chang, C.P.7
Lee, H.H.8
-
159
-
-
0033570376
-
T beta R-I(6A) is a candidate tumor susceptibility allele
-
(1999)
Cancer Res
, vol.59
, pp. 5678-5682
-
-
Pasche, B.1
Kolachana, P.2
Nafa, K.3
Satagopan, J.4
Chen, Y.G.5
Lo, R.S.6
Brener, D.7
Yang, D.8
Kirstein, L.9
Oddoux, C.10
Ostrer, H.11
Vineis, P.12
Varesco, L.13
Jhanwar, S.14
Luzzatto, L.15
Massague, J.16
Offit, K.17
-
160
-
-
15444350405
-
Type I transforming growth factor beta receptor maps to 9q22 and exhibits a polymorphism and a rare variant within a polyalanine tract
-
(1998)
Cancer Res
, vol.58
, pp. 2727-2732
-
-
Pasche, B.1
Luo, Y.2
Rao, P.H.3
Nimer, S.D.4
Dmitrovsky, E.5
Caron, P.6
Luzzatto, L.7
Offit, K.8
Cordoncardo, C.9
Renault, B.10
Satagopan, J.M.11
Murty, V.S.12
Massague, J.13
-
162
-
-
6844240210
-
Down-regulated expression of transforming growth factor beta I mrna in endometrial carcinoma
-
(1998)
Br J Cancer
, vol.77
, pp. 1260-1266
-
-
Perlino, E.1
Loverro, G.2
Maiorano, E.3
Giannini, T.4
Cazzolla, A.5
Napoli, A.6
Fiore, M.G.7
Ricco, R.8
Marra, E.9
Selvaggi, L.10
-
173
-
-
0032865413
-
SMAD genes in juvenile polyposis
-
(1999)
Genes, Chromosomes & Cancer
, vol.26
, pp. 54-61
-
-
Roth, S.1
Sistonen, P.2
Salovaara, R.3
Hemminki, A.4
Loukola, A.5
Johansson, M.6
Avizienyte, E.7
Cleary, K.A.8
Lynch, P.9
Amos, C.I.10
Kristo, P.11
Mecklin, J.P.12
Kellokumpu, I.13
Jarvinen, H.14
Aaltonen, L.A.15
-
175
-
-
0030738435
-
Transforming growth factorbeta receptor type 2 mutations and microsatellite instability in sporadic colorectal adenomas and carcinomas
-
(1997)
Am J Pathol
, vol.151
, pp. 33-35
-
-
Samowitz, W.S.1
Slattery, M.L.2
-
176
-
-
0031105963
-
Differential transforming growth factor-beta secretion in adenocarcinoma and squamous cell carcinoma of the uterine cervix
-
(1997)
Gynecol Oncol
, vol.64
, pp. 477-480
-
-
Santin, A.D.1
Hermonat, P.L.2
Hiserodt, J.C.3
Fruehauf, J.4
Schranz, V.5
Barclay, D.6
Pecorelli, S.7
Parham, G.P.8
-
178
-
-
0029075039
-
In situ analysis of transforming growth factor-beta-s (TGF-beta-1, TGF-beta-2, TGF-beta-3), and TGF-beta type II receptor expression in malignant melanoma
-
(1995)
Carcinogenesis
, vol.16
, pp. 1499-1503
-
-
Schmid, P.1
Itin, P.2
Ruffi, T.3
-
182
-
-
0032784406
-
DPC4/SMAD4 gene alterations in human cancer, and theft functional implications
-
(1999)
Ann Oncol
, vol.10
, pp. 4-59
-
-
Schutte, M.1
-
183
-
-
0033587016
-
DPC4/SMAD4 mediated tumor suppression of colon carcinoma cells is associated with reduced urokinase expression
-
(1999)
Oncogene
, vol.18
, pp. 3152-3158
-
-
Schwarte-Waldoff, I.1
Klein, S.2
Blass-Kampmann, S.3
Hintelmann, A.4
Eilert, C.5
Dreschers, S.6
Kalthoff, H.7
Hahn, S.A.8
Schmiegel, W.9
-
186
-
-
0343415643
-
Mutational analysis of the transforming growth factor beta receptor type II gene in hereditary nonpolyposis colorectal cancer and early-onset colorectal cancer patients
-
(2000)
Clin Cancer Res
, vol.6
, pp. 536-540
-
-
Shin, K.H.1
Park, Y.J.2
Park, J.G.3
-
197
-
-
2642614530
-
Transforming growth factorbeta-1 is a new form of tumor suppressor with true haploid insufficiency
-
(1998)
Nature Med
, vol.4
, pp. 802-807
-
-
Tang, B.W.1
Bottinger, E.P.2
Jakowlew, S.B.3
Bagnall, K.M.4
Mariano, J.5
Anver, M.R.6
Letterio, J.J.7
Wakefield, L.M.8
-
198
-
-
0034719335
-
DCC and SMAD4 alterations in human colorectal and pancreatic tumor dissemination
-
(2000)
Oncogene
, vol.19
, pp. 546-555
-
-
Tarafa, G.1
Villanueva, A.2
Farre, L.3
Rodriguez, J.4
Musulen, E.5
Reyes, G.6
Seminago, R.7
Olmedo, E.8
Paules, A.B.9
Peinado, M.A.10
Bachs, O.11
Capella, G.12
-
200
-
-
0032864305
-
Does mutation of transforming growth factor-beta type II receptor gene play an important role in colorectal polyps?
-
(1999)
Dig Dis Sci
, vol.44
, pp. 1803-1809
-
-
Togo, G.1
Okamoto, M.2
Shiratori, Y.3
Yamaji, H.4
Kate, J.5
Matsumura, M.6
Sano, T.7
Motojima, T.8
Omata, M.9
-
205
-
-
12644296993
-
Dpc 4/smad 4 in non-pancreatic tumors with frequent loh 18q21 and in hematological malignancies
-
(1997)
Int J Oncol
, vol.10
, pp. 257-260
-
-
Verbeek, W.1
Spirin, K.2
Hatta, Y.3
Miller, C.4
Kawamata, N.5
Takeuchi, S.6
Koike, M.7
Asou, H.8
Simpson, J.F.9
Koeffler, H.P.10
-
206
-
-
7844240481
-
Disruption of the antiproliferative TGF-beta signaling pathways in human pancreatic cancer cells
-
(1998)
Oncogene
, vol.17
, pp. 1969-1978
-
-
Villanueva, A.1
Garcia, C.2
Paules, A.B.3
Vicente, M.4
Megias, M.5
Reyes, G.6
Devillalonga, P.7
Agell, N.8
Lluis, F.9
Bachs, O.10
Capella, G.11
-
207
-
-
13344287035
-
Analysis of microsatellite instability in chronic lymphoproliferative disorders
-
(1996)
Ann Hematol
, vol.72
, pp. 67-71
-
-
Volpe, G.1
Gamberi, B.2
Pastore, C.3
Roetto, A.4
Pautasso, M.5
Parvis, G.6
Camaschella, C.7
Mazza, U.8
Saglio, G.9
Gaidano, G.10
-
209
-
-
0033227597
-
Mutation analysis of the Smad3 gene in human ovarian cancers
-
(1999)
Int J Oncol
, vol.15
, pp. 949-953
-
-
Wang, D.1
Kanuma, T.2
Takama, F.3
Mizumuma, H.4
Ibuki, Y.5
Wake, N.6
Mogi, A.7
Shitara, Y.8
Hagiwara, K.9
Takenoshita, S.10
-
210
-
-
0029131403
-
Demonstration that mutation of the type II transforming growth factor beta receptor inactivates its tumor suppressor activity in replication error-positive colon carcinoma cells
-
(1995)
J Biol Chem
, vol.270
, pp. 22044-22049
-
-
Wang, J.1
Sun, L.Z.2
Myeroff, L.3
Wang, X.F.4
Gentry, L.E.5
Yan, J.H.6
Liang, J.R.7
Zborowska, E.8
Markowitz, S.9
Willson, J.K.V.10
Brattain, M.G.11
-
212
-
-
0034032009
-
Loss of expression of Dpc4 in pancreatic intraepithelial neoplasia: Evidence that DPC4 inactivation occurs late in neoplastic progression
-
(2000)
Cancer Res
, vol.60
, pp. 2002-2006
-
-
Wilentz, R.E.1
Iacobuzio-Donahue, C.A.2
Argani, P.3
McCarthy, D.M.4
Parsons, J.L.5
Yeo, C.J.6
Kern, S.E.7
Hruban, R.H.8
-
214
-
-
0034194138
-
Allelic loss at SMAD4 in polyps from juvenile polyposis patients and use of fluorescence in situ hybridization to demonstrate clonal origin of the epithelium
-
(2000)
Cancer Res
, vol.60
, pp. 2477-2482
-
-
Woodford-Richens, K.1
Williamson, J.2
Bevan, S.3
Young, J.4
Leggett, B.5
Frayling, I.6
Thway, Y.7
Hodgson, S.8
Kim, J.C.9
Iwama, T.10
Novelli, M.11
Sheer, D.12
Poulsom, R.13
Wright, N.14
Houlston, R.15
Tomlinson, I.16
-
216
-
-
0034712832
-
Mutations in the tumor suppressors Smad2 and Smad4 inactivate transforming growth factor beta signaling by targeting Smads to the ubiquitin-proteasome pathway
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 4820-4825
-
-
Xu, J.1
Attisano, L.2
-
218
-
-
0034705036
-
Ski acts as a co-repressor with Smad2 and Smad3 to regulate the response to type beta transforming growth factor
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 5924-5929
-
-
Xu, W.D.1
Angelis, K.2
Danielpour, D.3
Haddad, M.M.4
Bischof, O.5
Campisi, J.6
Stavnezer, E.7
Medrano, E.E.8
-
219
-
-
0034611611
-
Haploid loss of the tumor suppressor Smad4/Dpc4 initiates gastric polyposis and cancer in mice
-
(2000)
Oncogene
, vol.19
, pp. 1868-1874
-
-
Xu, X.L.1
Brodie, S.G.2
Yang, X.3
Im, Y.H.4
Parks, W.T.5
Chen, L.6
Zhou, Y.X.7
Weinstein, M.8
Kim, S.J.9
Deng, C.X.10
-
223
-
-
0034604108
-
Heterogeneities in the biological and biochemical functions of Smad2 and Smad4 mutants naturally occurring in human lung cancers
-
(2000)
Oncogene
, vol.19
, pp. 2305-2311
-
-
Yanagisawa, K.1
Uchida, K.2
Nagatake, M.3
Masuda, A.4
Sugiyama, M.5
Saito, T.6
Yamaki, K.7
Takahashi, T.8
Osada, H.9
-
224
-
-
0031981196
-
Transforming growth factor beta type II receptor (Tgf-beta-RII) mutation in gastric lymphoma without mutator phenotype
-
(1998)
Pathol Int
, vol.48
, pp. 134-137
-
-
Yasumi, K.1
Guo, R.J.2
Hanai, H.3
Arai, H.4
Kaneko, E.5
Konno, H.6
Takenoshita, S.7
Hagiwara, K.8
Sugimura, H.9
-
226
-
-
0032918414
-
TGF-beta signaling blockade inhibits PTHrP secretion by breast cancer cells and bone metastases development
-
(1999)
J Clin Invest
, vol.103
, pp. 197-206
-
-
Yin, J.J.1
Selander, K.2
Chirgwin, J.M.3
Dallas, M.4
Grubbs, B.G.5
Wieser, R.6
Massague, J.7
Mundy, G.R.8
Guise, T.A.9
-
227
-
-
0034234736
-
Growth control of human biliary epithelial cells by interleukin 6, hepatocyte growth factor, transforming growth factor beta 1, and actvin A: Comparison of a cholangiocarcinoma cell line with primary cultures of non-neoplastic biliary epithelial cells
-
(2000)
Hepatology
, vol.32
, pp. 26-35
-
-
Yokomuro, S.1
Tsuji, H.2
Lunz, J.G.3
Sakamoto, T.4
Ezure, T.5
Murase, N.6
Demetris, A.J.7
-
230
-
-
0032936925
-
Involvement of mutations in the DPC4 promoter in endometrial carcinoma development
-
(1999)
Mol Carcinog
, vol.25
, pp. 64-72
-
-
Zhou, Y.1
Kato, H.2
Shan, D.3
Minami, R.4
Kitazawa, S.5
Matsuda, T.6
Arima, T.7
Barrett, J.C.8
Wake, N.9
|