-
1
-
-
0024292632
-
The effect of thymus environment on T cell development and tolerance
-
Marrack, P. et al. The effect of thymus environment on T cell development and tolerance. Cell 53, 627-634 (1988).
-
(1988)
Cell
, vol.53
, pp. 627-634
-
-
Marrack, P.1
-
2
-
-
0024381358
-
A nondeletional mechanism of thymic self tolerance
-
Ramsdell, F., Lantz, T. & Fowlkes, B.J. A nondeletional mechanism of thymic self tolerance. Science 246, 1038-1041 (1989).
-
(1989)
Science
, vol.246
, pp. 1038-1041
-
-
Ramsdell, F.1
Lantz, T.2
Fowlkes, B.J.3
-
3
-
-
0025320109
-
Clonal deletion and clonal anergy in the thymus induced by cellular elements with different radiation sensitivities
-
Roberts, J.L., Sharrow, S.O. & Singer, A. Clonal deletion and clonal anergy in the thymus induced by cellular elements with different radiation sensitivities. J. Exp. Med. 171, 935-940 (1990).
-
(1990)
J. Exp. Med.
, vol.171
, pp. 935-940
-
-
Roberts, J.L.1
Sharrow, S.O.2
Singer, A.3
-
4
-
-
18644365981
-
+ T cells: Evidence from a lymphopenic T cell model
-
+ T cells: evidence from a lymphopenic T cell model. Immunity 17 425-436 (2002).
-
(2002)
Immunity
, vol.17
, pp. 425-436
-
-
Bhandoola, A.1
-
5
-
-
0036360019
-
The enemy within: Keeping self-reactive T cells at bay in the periphery
-
Walker, L.S. & Abbas, A.K. The enemy within: keeping self-reactive T cells at bay in the periphery. Nat. Rev. Immunol. 2, 11-19 (2002).
-
(2002)
Nat. Rev. Immunol.
, vol.2
, pp. 11-19
-
-
Walker, L.S.1
Abbas, A.K.2
-
6
-
-
2442484053
-
+ regulatory T cells for immunologic self-tolerance and negative control of immune responses
-
+ regulatory T cells for immunologic self-tolerance and negative control of immune responses. Annu. Rev. Immunol. 22, 531-562 (2004).
-
(2004)
Annu. Rev. Immunol.
, vol.22
, pp. 531-562
-
-
Sakaguchi, S.1
-
7
-
-
0035180065
-
+ regulatory T cells: Their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance
-
+ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance. Immunol. Rev. 182, 18-32 (2001).
-
(2001)
Immunol. Rev.
, vol.182
, pp. 18-32
-
-
Sakaguchi, S.1
-
9
-
-
0036597371
-
+ suppressor T cells: More questions than answers
-
+ suppressor T cells: more questions than answers. Nat. Rev. Immunol. 2, 389-400 (2002).
-
(2002)
Nat. Rev. Immunol.
, vol.2
, pp. 389-400
-
-
Shevach, E.M.1
-
10
-
-
0034679560
-
+ regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4
-
+ regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4. J. Exp. Med. 192 303-310 (2000).
-
(2000)
J. Exp. Med.
, vol.192
, pp. 303-310
-
-
Takahashi, T.1
-
11
-
-
0034679567
-
+ regulatory cells that control intestinal inflammation
-
+ regulatory cells that control intestinal inflammation. J. Exp. Med. 192, 295-302 (2000).
-
(2000)
J. Exp. Med.
, vol.192
, pp. 295-302
-
-
Read, S.1
Malmstrom, V.2
Powrie, F.3
-
13
-
-
0036195161
-
+ immunoregulatory T cells: Gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor
-
+ immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor. Immunity 16, 311-323 (2002).
-
(2002)
Immunity
, vol.16
, pp. 311-323
-
-
McHugh, R.S.1
-
15
-
-
0035320679
-
+ regulatory T cells induced by an agonist self-peptide
-
+ regulatory T cells induced by an agonist self-peptide. Nat. Immunol. 2, 301-306 (2001).
-
(2001)
Nat. Immunol.
, vol.2
, pp. 301-306
-
-
Jordan, M.S.1
-
16
-
-
0036345337
-
Origin of regulatory T cells with known specificity for antigen
-
Apostolou, I., Sarukhan, A., Klein, L. & von Boehmer, H. Origin of regulatory T cells with known specificity for antigen. Nat. Immunol. 3, 756-763 (2002).
-
(2002)
Nat. Immunol.
, vol.3
, pp. 756-763
-
-
Apostolou, I.1
Sarukhan, A.2
Klein, L.3
von Boehmer, H.4
-
17
-
-
0347785480
-
Control of regulatory T cell development by the transcription factor Foxp3
-
Hori, S., Nomura, T. & Sakaguchi, S. Control of regulatory T cell development by the transcription factor Foxp3. Science 299 1057-1061 (2003).
-
(2003)
Science
, vol.299
, pp. 1057-1061
-
-
Hori, S.1
Nomura, T.2
Sakaguchi, S.3
-
20
-
-
0033526862
-
Several different cell surface molecules control negative selection of medullary thymocytes
-
Kishimoto, H. & Sprent, J. Several different cell surface molecules control negative selection of medullary thymocytes. J. Exp. Med. 190, 65-73 (1999).
-
(1999)
J. Exp. Med.
, vol.190
, pp. 65-73
-
-
Kishimoto, H.1
Sprent, J.2
-
21
-
-
0027957577
-
+ thymocytes by T cell receptor-induced apoptosis requires a costimulatory signal that can be provided by CD28
-
+ thymocytes by T cell receptor-induced apoptosis requires a costimulatory signal that can be provided by CD28. J. Exp. Med. 179, 709-713 (1994).
-
(1994)
J. Exp. Med.
, vol.179
, pp. 709-713
-
-
Punt, J.A.1
Osborne, B.A.2
Takahama, Y.3
Sharrow, S.O.4
Singer, A.5
-
22
-
-
0030732750
-
+ thymocytes by two distinct mechanisms differing in their requirement for CD28 costimulation: Implications for negative selection in the thymus
-
+ thymocytes by two distinct mechanisms differing in their requirement for CD28 costimulation: implications for negative selection in the thymus. J. Exp. Med. 186, 1911-1922 (1997).
-
(1997)
J. Exp. Med.
, vol.186
, pp. 1911-1922
-
-
Punt, J.A.1
Havran, W.2
Abe, R.3
Sarin, A.4
Singer, A.5
-
24
-
-
0033682056
-
+ immunoregulatory T cells that control autoimmune diabetes
-
+ immunoregulatory T cells that control autoimmune diabetes. Immunity 12, 431-440 (2000).
-
(2000)
Immunity
, vol.12
, pp. 431-440
-
-
Salomon, B.1
-
25
-
-
0141920662
-
+ regulatory T cells
-
+ regulatory T cells. J. Immunol. 171 3348-3352 (2003).
-
(2003)
J. Immunol.
, vol.171
, pp. 3348-3352
-
-
Tang, Q.1
-
26
-
-
0025947895
-
CD28 delivers a costimulatory signal involved in antigen-specific IL-2 production by human T cells
-
Jenkins, M.K., Taylor, P.S., Norton, S.D. & Urdahl, K.B. CD28 delivers a costimulatory signal involved in antigen-specific IL-2 production by human T cells. J. Immunol. 147, 2461-2466 (1991).
-
(1991)
J. Immunol.
, vol.147
, pp. 2461-2466
-
-
Jenkins, M.K.1
Taylor, P.S.2
Norton, S.D.3
Urdahl, K.B.4
-
27
-
-
0029163387
-
CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL
-
Boise, L.H. et al. CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL. Immunity 3 87-98 (1995).
-
(1995)
Immunity
, vol.3
, pp. 87-98
-
-
Boise, L.H.1
-
28
-
-
0035757397
-
T-cell regulation by CD28 and CTLA-4
-
Alegre, M.L., Frauwirth, K.A. & Thompson, C.B. T-cell regulation by CD28 and CTLA-4. Nat. Rev. Immunol. 1, 220-228 (2001).
-
(2001)
Nat. Rev. Immunol.
, vol.1
, pp. 220-228
-
-
Alegre, M.L.1
Frauwirth, K.A.2
Thompson, C.B.3
-
29
-
-
0029894534
-
Antigen compartmentation and T helper cell tolerance induction
-
Oehen, S., Feng, L., Xia, Y., Surh, C.D. & Hedrick, S.M. Antigen compartmentation and T helper cell tolerance induction. J. Exp. Med. 183, 2617-2626 (1996).
-
(1996)
J. Exp. Med.
, vol.183
, pp. 2617-2626
-
-
Oehen, S.1
Feng, L.2
Xia, Y.3
Surh, C.D.4
Hedrick, S.M.5
-
30
-
-
0028182749
-
Binding of phosphatidylinositol-3-OH kinase to CD28 is required for T-cell signalling
-
Pages, F et al. Binding of phosphatidylinositol-3-OH kinase to CD28 is required for T-cell signalling. Nature 369, 327-329 (1994).
-
(1994)
Nature
, vol.369
, pp. 327-329
-
-
Pages, F.1
-
31
-
-
0028221022
-
T-cell antigen CD28 interacts with the lipid kinase phosphatidylinositol 3-kinase by a cytoplasmic Tyr(P)-Met-Xaa-Met motif
-
Prasad, K.V. et al. T-cell antigen CD28 interacts with the lipid kinase phosphatidylinositol 3-kinase by a cytoplasmic Tyr(P)-Met-Xaa-Met motif. Proc. Natl. Acad. Sci. USA 91, 2834-2838 (1994).
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 2834-2838
-
-
Prasad, K.V.1
-
32
-
-
0031255110
-
The SH3 domain of Itk/Emt binds to proline-rich sequences in the cytoplasmic domain of the T cell costimulatory receptor CD28
-
Marengere, L.E. et al. The SH3 domain of Itk/Emt binds to proline-rich sequences in the cytoplasmic domain of the T cell costimulatory receptor CD28. J. Immunol. 159, 3220-3229 (1997).
-
(1997)
J. Immunol.
, vol.159
, pp. 3220-3229
-
-
Marengere, L.E.1
-
33
-
-
0033517125
-
Proline residues in CD28 and the Src homology (SH)3 domain of Lck are required for T cell costimulation
-
Holdorf, A.D. et al. Proline residues in CD28 and the Src homology (SH)3 domain of Lck are required for T cell costimulation. J. Exp. Med. 190, 375-384 (1999).
-
(1999)
J. Exp. Med.
, vol.190
, pp. 375-384
-
-
Holdorf, A.D.1
-
34
-
-
7144259082
-
Regulatory CD4 T cells: Expression of IL-2Rα chain, resistance to clonal deletion and IL-2 dependency
-
Papiernik, M., de Moraes, M.L., Pontoux, C., Vasseur, F. & Penit, C. Regulatory CD4 T cells: expression of IL-2Rα chain, resistance to clonal deletion and IL-2 dependency. Int. Immunol. 10, 371-378 (1998).
-
(1998)
Int. Immunol.
, vol.10
, pp. 371-378
-
-
Papiernik, M.1
de Moraes, M.L.2
Pontoux, C.3
Vasseur, F.4
Penit, C.5
-
35
-
-
0036669298
-
CD4 regulatory T cells prevent lethal autoimmunity in IL-2Rβ-deficient mice. Implications for the nonredundant function of IL-2
-
Malek, T.R., Yu, A., Vincek, V., Scibelli, P. & Kong, L. CD4 regulatory T cells prevent lethal autoimmunity in IL-2Rβ-deficient mice. Implications for the nonredundant function of IL-2. Immunity 17 167-178 (2002).
-
(2002)
Immunity
, vol.17
, pp. 167-178
-
-
Malek, T.R.1
Yu, A.2
Vincek, V.3
Scibelli, P.4
Kong, L.5
-
37
-
-
0030993441
-
Surface molecules that drive T cell development in vitro in the absence of thymic epithelium and in the absence of lineage-specific signals
-
Cibotti, R., Punt, J.A., Dash, K.S., Sharrow, S.O. & Singer, A. Surface molecules that drive T cell development in vitro in the absence of thymic epithelium and in the absence of lineage-specific signals. Immunity 6, 245-255 (1997).
-
(1997)
Immunity
, vol.6
, pp. 245-255
-
-
Cibotti, R.1
Punt, J.A.2
Dash, K.S.3
Sharrow, S.O.4
Singer, A.5
-
38
-
-
0035284806
-
Maturation versus death of developing double-positive thymocytes reflects competing effects on Bcl-2 expression and can be regulated by the intensity of CD28 costimulation
-
McKean, D.J. et al. Maturation versus death of developing double-positive thymocytes reflects competing effects on Bcl-2 expression and can be regulated by the intensity of CD28 costimulation. J. Immunol. 166, 3468-3475 (2001).
-
(2001)
J. Immunol.
, vol.166
, pp. 3468-3475
-
-
McKean, D.J.1
-
40
-
-
0036195934
-
Regulation of Lck activity by CD4 and CD28 in the immunological synapse
-
Holdorf, A.D., Lee, K.H., Burack, W.R., Allen, P.M. & Shaw, A.S. Regulation of Lck activity by CD4 and CD28 in the immunological synapse. Nat. Immunol. 3, 259-264 (2002).
-
(2002)
Nat. Immunol.
, vol.3
, pp. 259-264
-
-
Holdorf, A.D.1
Lee, K.H.2
Burack, W.R.3
Allen, P.M.4
Shaw, A.S.5
-
41
-
-
0033613826
-
T lymphocyte costimulation mediated by reorganization of membrane microdomains
-
Viola, A., Schroeder, S., Sakakibara, Y. & Lanzavecchia, A. T lymphocyte costimulation mediated by reorganization of membrane microdomains. Science 283, 680-682 (1999).
-
(1999)
Science
, vol.283
, pp. 680-682
-
-
Viola, A.1
Schroeder, S.2
Sakakibara, Y.3
Lanzavecchia, A.4
-
42
-
-
0027281691
-
Differential T cell costimulatory requirements in CD28-deficient mice
-
Shahinian, A. et al. Differential T cell costimulatory requirements in CD28-deficient mice. Science 261, 609-612 (1993).
-
(1993)
Science
, vol.261
, pp. 609-612
-
-
Shahinian, A.1
-
43
-
-
0035319244
-
A point mutation in CD28 distinguishes proliferative signals from survival signals
-
Okkenhaug, K. et al. A point mutation in CD28 distinguishes proliferative signals from survival signals. Nat. Immunol. 2, 325-332 (2001).
-
(2001)
Nat. Immunol.
, vol.2
, pp. 325-332
-
-
Okkenhaug, K.1
-
44
-
-
0035340150
-
Cutting edge: Distinct motifs within CD28 regulate T cell proliferation and induction of Bcl-XL
-
Burr, J.S. et al. Cutting edge: distinct motifs within CD28 regulate T cell proliferation and induction of Bcl-XL. J. Immunol. 166, 5331-5335 (2001).
-
(2001)
J. Immunol.
, vol.166
, pp. 5331-5335
-
-
Burr, J.S.1
-
45
-
-
0035869402
-
Critical requirement for the membrane-proximal cytosolic tyrosine residue for CD28-mediated costimulation in vivo
-
Harada, Y. et al. Critical requirement for the membrane-proximal cytosolic tyrosine residue for CD28-mediated costimulation in vivo. J. Immunol. 166, 3797-3803 (2001).
-
(2001)
J. Immunol.
, vol.166
, pp. 3797-3803
-
-
Harada, Y.1
-
46
-
-
11144358624
-
Distinct regions in the CD28 cytoplasmic domain are required for T helper type 2 differentiation
-
Andres, P.G. et al. Distinct regions in the CD28 cytoplasmic domain are required for T helper type 2 differentiation. Nat. Immunol. 5, 435-442 (2004).
-
(2004)
Nat. Immunol.
, vol.5
, pp. 435-442
-
-
Andres, P.G.1
-
47
-
-
0033696599
-
+ thymocytes initially terminate CD8 transcription even when differentiating into CD8+ T cells
-
+ thymocytes initially terminate CD8 transcription even when differentiating into CD8+ T cells. Immunity 13, 59-71 (2000).
-
(2000)
Immunity
, vol.13
, pp. 59-71
-
-
Brugnera, E.1
-
48
-
-
0025751550
-
bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes
-
Sentman, C.L., Shutter, J.R., Hockenbery, D., Kanagawa, O. & Korsmeyer, S.J. bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes. Cell 67, 879-888 (1991).
-
(1991)
Cell
, vol.67
, pp. 879-888
-
-
Sentman, C.L.1
Shutter, J.R.2
Hockenbery, D.3
Kanagawa, O.4
Korsmeyer, S.J.5
-
49
-
-
0024444304
-
+ T cells in transgenic mice expressing a class II MHC-restricted antigen receptor
-
+ T cells in transgenic mice expressing a class II MHC-restricted antigen receptor. Nature 341, 746-749 (1989).
-
(1989)
Nature
, vol.341
, pp. 746-749
-
-
Kaye, J.1
|