TGF-β1 down-regulates Th2 development and results in decreased IL-4-induced STAT6 activation and GATA-3 expression

European Journal of Immunology

Volumn 30, Issue 9, 2000, Pages 2639-2649

  Heath, Victoria L ^a   Murphy, Erin E ^a   Crain, Chad ^a   Tomlinson, Michael G ^a   O'Garra, Anne ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

IL 4 signaling; TGF ; Th2 development

Indexed keywords

ANTIBODY; CD4 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 4; OVALBUMIN; STAT6 PROTEIN; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR GATA 3; TRANSFORMING GROWTH FACTOR BETA1; DNA BINDING PROTEIN; GATA3 PROTEIN, MOUSE; MAF PROTEIN, MOUSE; ONCOPROTEIN; STAT6 PROTEIN, MOUSE; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR C MAF; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ARTICLE; DOWN REGULATION; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOREGULATION; LYMPHOCYTE DIFFERENTIATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE; TH2 CELL; ANIMAL; BAGG ALBINO MOUSE; BIOSYNTHESIS; PHOSPHORYLATION; PHYSIOLOGY; TH1 CELL;

ANIMALS; DNA-BINDING PROTEINS; DOWN-REGULATION; GATA3 TRANSCRIPTION FACTOR; INTERFERON TYPE II; INTERLEUKIN-4; MICE; MICE, INBRED BALB C; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-MAF; STAT6 TRANSCRIPTION FACTOR; TH1 CELLS; TH2 CELLS; TRANS-ACTIVATORS; TRANSFORMING GROWTH FACTOR BETA;

EID: 0033623339     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4141(200009)30:9<2639::AID-IMMU2639>3.0.CO;2-7     Document Type: Article

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