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Volumn 42, Issue 4, 2010, Pages 590-611

Interactions of dietary phytochemicals with ABC transporters: Possible implications for drug disposition and multidrug resistance in cancer

Author keywords

ABC transporter; Cancer; Multidrug resistance; Pharmacokinetics; Phytochemical

Indexed keywords

ABC TRANSPORTER; ANTINEOPLASTIC AGENT; APIGENIN; BIOCHANIN A; CATECHIN; CURCUMIN; CYANIDIN 3 GLUCOSIDE; DAIDZEIN; ELACRIDAR; EPICATECHIN; EPIGALLOCATECHIN; FLAVANOL DERIVATIVE; FLAVONE DERIVATIVE; FLAVONOID; FLAVONOL DERIVATIVE; GALLOCATECHIN; GENISTEIN; ISOFLAVONE DERIVATIVE; LUTEOLIN; MALVIDIN CHLORIDE; MYRICETIN; NARINGENIN; PELARGONIDIN; PLANT MEDICINAL PRODUCT; PROANTHOCYANIDIN DERIVATIVE; PUERARIN; QUERCETIN; RESVERATROL; SILYMARIN; TARIQUIDAR; UNINDEXED DRUG; XENOBIOTIC AGENT; ZOSUQUIDAR;

EID: 77957594068     PISSN: 03602532     EISSN: 10979883     Source Type: Journal    
DOI: 10.3109/03602531003758690     Document Type: Review
Times cited : (45)

References (262)
  • 1
    • 0033199027 scopus 로고    scopus 로고
    • The mouse Bcrp1/Mxr/Abcp gene: Amplification and overexpression in cell lines selected for resistance to topotecan, mitoxantrone, or doxorubicin
    • Allen, J. D., Brinkhuis, R. F., Wijnholds, J., Schinkel, A. H. (1999). The mouse Bcrp1/Mxr/Abcp gene: amplification and overexpression in cell lines selected for resistance to topotecan, mitoxantrone, or doxorubicin. Cancer Res 59:4237-4241.
    • (1999) Cancer Res , vol.59 , pp. 4237-4241
    • Allen, J.D.1    Brinkhuis, R.F.2    Wijnholds, J.3    Schinkel, A.H.4
  • 2
    • 0000890967 scopus 로고    scopus 로고
    • Potent and specific inhibition of the breast cancer resistance protein multidrug transporter in vitro and in mouse intestine by a novel analogue of fumitre- morgin C
    • Allen, J. D., van Loevezijn, A., Lakhai, J. M., van der Valk, M., van Tellingen, O., Reid, G., et al. (2002). Potent and specific inhibition of the breast cancer resistance protein multidrug transporter in vitro and in mouse intestine by a novel analogue of fumitre- morgin C. Mol Cancer Ther 1:417-425.
    • (2002) Mol Cancer Ther , vol.1 , pp. 417-425
    • Allen, J.D.1    Van Loevezijn, A.2    Lakhai, J.M.3    Van Der Valk, M.4    Van Tellingen, O.5    Reid, G.6
  • 3
    • 63449139456 scopus 로고    scopus 로고
    • Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding
    • Aller, S. G., Yu, J., Ward, A., Weng, Y., Chittaboina, S., Zhuo, R., et al. (2009). Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding. Science 323:1718-1722.
    • (2009) Science , vol.323 , pp. 1718-1722
    • Aller, S.G.1    Yu, J.2    Ward, A.3    Weng, Y.4    Chittaboina, S.5    Zhuo, R.6
  • 4
    • 55949084512 scopus 로고    scopus 로고
    • Biological activities of curcumin and its analogues (Congeners) made by man and mother nature
    • Anand, P., Thomas, S. G., Kunnumakkara, A. B., Sundaram, C., Harikumar, K. B., Sung, B., et al. (2008). Biological activities of curcumin and its analogues (Congeners) made by man and mother nature. Biochem Pharmacol 76:1590-1611.
    • (2008) Biochem Pharmacol , vol.76 , pp. 1590-1611
    • Anand, P.1    Thomas, S.G.2    Kunnumakkara, A.B.3    Sundaram, C.4    Harikumar, K.B.5    Sung, B.6
  • 5
    • 34748877360 scopus 로고    scopus 로고
    • Involvement of breast cancer resistance protein (ABCG2) in the biliary excretion mechanism of fluoroquinolones
    • Ando, T., Kusuhara, H., Merino, G., Alvarez, A. I., Schinkel, A. H., Sugiyama, Y. (2007). Involvement of breast cancer resistance protein (ABCG2) in the biliary excretion mechanism of fluoroquinolones. Drug Metab Dispos 35:1873-1879.
    • (2007) Drug Metab Dispos , vol.35 , pp. 1873-1879
    • Ando, T.1    Kusuhara, H.2    Merino, G.3    Alvarez, A.I.4    Schinkel, A.H.5    Sugiyama, Y.6
  • 6
    • 0037103569 scopus 로고    scopus 로고
    • Modulation of P-glycoprotein expression and function by curcumin in multidrug-resistant human KB cells
    • Anuchapreeda, S., Leechanachai, P., Smith, M. M., Ambudkar, S. V., Limtrakul, P. N. (2002). Modulation of P-glycoprotein expression and function by curcumin in multidrug-resistant human KB cells. Biochem Pharmacol 64:573-582.
    • (2002) Biochem Pharmacol , vol.64 , pp. 573-582
    • Anuchapreeda, S.1    Leechanachai, P.2    Smith, M.M.3    Ambudkar, S.V.4    Limtrakul, P.N.5
  • 7
    • 12844250848 scopus 로고    scopus 로고
    • Modulation of P-glycoprotein-mediated multidrug resistance in K562 leukemic cells by indole-3-carbinol
    • Arora, A., Seth, K., Kalra, N., Shukla, Y. (2005). Modulation of P-glycoprotein-mediated multidrug resistance in K562 leukemic cells by indole-3-carbinol. Toxicol Appl Pharmacol 202: 237-243.
    • (2005) Toxicol Appl Pharmacol , vol.202 , pp. 237-243
    • Arora, A.1    Seth, K.2    Kalra, N.3    Shukla, Y.4
  • 8
    • 3042814442 scopus 로고    scopus 로고
    • Reversal of P-glycoprotein- mediated multidrug resistance by diallyl sulfide in K562 leukemic cells and in mouse liver
    • Arora, A., Seth, K., Shukla, Y. (2004). Reversal of P-glycoprotein- mediated multidrug resistance by diallyl sulfide in K562 leukemic cells and in mouse liver. Carcinogenesis 25:941-949.
    • (2004) Carcinogenesis , vol.25 , pp. 941-949
    • Arora, A.1    Seth, K.2    Shukla, Y.3
  • 9
    • 0037469098 scopus 로고    scopus 로고
    • Modulation of vinca-alkaloid induced P-glycoprotein expression by indole-3-carbinol
    • Arora, A., Shukla, Y. (2003). Modulation of vinca-alkaloid induced P-glycoprotein expression by indole-3-carbinol. Cancer Lett 189:167-173.
    • (2003) Cancer Lett , vol.189 , pp. 167-173
    • Arora, A.1    Shukla, Y.2
  • 10
    • 0344823703 scopus 로고    scopus 로고
    • Neuroprotection by bioac- tive components in medicinal and food plant extracts
    • Aruoma, O. I., Bahorun, T., Jen, L-S. (2003). Neuroprotection by bioac- tive components in medicinal and food plant extracts. Mutat Res Rev Mutat Res 544:203-215.
    • (2003) Mutat Res Rev Mutat Res , vol.544 , pp. 203-215
    • Aruoma, O.I.1    Bahorun, T.2    Jen, L.-S.3
  • 11
    • 27844474247 scopus 로고    scopus 로고
    • Drug discovery from medicinal plants
    • Balunas, M. J., Kinghorn, A. D. (2005). Drug discovery from medicinal plants. Life Sci 78:431-441.
    • (2005) Life Sci , vol.78 , pp. 431-441
    • Balunas, M.J.1    Kinghorn, A.D.2
  • 12
    • 67650496175 scopus 로고    scopus 로고
    • 3,3'-diindolyl- methane enhances chemosensitivity of multiple chemothera- peutic agents in pancreatic cancer
    • Banerjee, S., Wang, Z., Kong, D., Sarkar, F. H. (2009). 3,3'-diindolyl- methane enhances chemosensitivity of multiple chemothera- peutic agents in pancreatic cancer. Cancer Res 69:5592-5600.
    • (2009) Cancer Res , vol.69 , pp. 5592-5600
    • Banerjee, S.1    Wang, Z.2    Kong, D.3    Sarkar, F.H.4
  • 13
    • 25444493107 scopus 로고    scopus 로고
    • Molecular evidence for increased antitumor activity of gemcitabine by genistein in vitro and in vivo using an orthotopic model of pancreatic cancer
    • Banerjee, S., Zhang, Y., Ali, S., Bhuiyan, M., Wang, Z., Chiao, P. J., et al. (2005). Molecular evidence for increased antitumor activity of gemcitabine by genistein in vitro and in vivo using an orthotopic model of pancreatic cancer. Cancer Res 65:9064-9072.
    • (2005) Cancer Res , vol.65 , pp. 9064-9072
    • Banerjee, S.1    Zhang, Y.2    Ali, S.3    Bhuiyan, M.4    Wang, Z.5    Chiao, P.J.6
  • 14
    • 33745962138 scopus 로고    scopus 로고
    • Therapeutic potential of resveratrol: The in vivo evidence
    • Baur, J. A., Sinclair, D. A. (2006). Therapeutic potential of resveratrol: the in vivo evidence. Nat Rev Drug Discov 5:493-506.
    • (2006) Nat Rev Drug Discov , vol.5 , pp. 493-506
    • Baur, J.A.1    Sinclair, D.A.2
  • 15
    • 0031468429 scopus 로고    scopus 로고
    • Evidence for reversal of multidrug resistance by quinine in LR73 cells without alteration of nuclear pirarubicin uptake and downregulation of mdr1 gene expression
    • Belhoussine, R., Morjani, H., Lahlil, R., Manfait, M. (1997). Evidence for reversal of multidrug resistance by quinine in LR73 cells without alteration of nuclear pirarubicin uptake and downregulation of mdr1 gene expression. Int J Cancer 73:600-606.
    • (1997) Int J Cancer , vol.73 , pp. 600-606
    • Belhoussine, R.1    Morjani, H.2    Lahlil, R.3    Manfait, M.4
  • 16
    • 33846441251 scopus 로고    scopus 로고
    • Multidrug resistance protein 4 protects bone marrow, thymus, spleen, and intestine from nucleotide analogue- induced damage
    • Belinsky, M. G., Guo, P., Lee, K., Zhou, F., Kotova, E., Grinberg, A., et al. (2007). Multidrug resistance protein 4 protects bone marrow, thymus, spleen, and intestine from nucleotide analogue- induced damage. Cancer Res 67:262-268.
    • (2007) Cancer Res , vol.67 , pp. 262-268
    • Belinsky, M.G.1    Guo, P.2    Lee, K.3    Zhou, F.4    Kotova, E.5    Grinberg, A.6
  • 17
    • 71949106600 scopus 로고    scopus 로고
    • The drug transporter-metabolism alliance: Uncovering and defining the interplay
    • Benet, L. Z. (2009). The drug transporter-metabolism alliance: uncovering and defining the interplay. Mol Pharm 6:1631-1643.
    • (2009) Mol Pharm , vol.6 , pp. 1631-1643
    • Benet, L.Z.1
  • 18
    • 2442451598 scopus 로고    scopus 로고
    • MRP8, a new member of ABC transporter superfamily, identified by EST database mining and gene prediction program, is highly expressed in breast cancer
    • Bera, T. K., Lee, S., Salvatore, G., Lee, B., Pastan, I. (2001). MRP8, a new member of ABC transporter superfamily, identified by EST database mining and gene prediction program, is highly expressed in breast cancer. Mol Med 7:509-516.
    • (2001) Mol Med , vol.7 , pp. 509-516
    • Bera, T.K.1    Lee, S.2    Salvatore, G.3    Lee, B.4    Pastan, I.5
  • 20
    • 34248205135 scopus 로고    scopus 로고
    • Polymeric nanoparticle-encapsulated curcumin ("nanocurcumin"): A novel strategy for human cancer therapy
    • Bisht, S., Feldmann, G., Soni, S., Ravi, R., Karikar, C., Maitra, A. (2007). Polymeric nanoparticle-encapsulated curcumin ("nanocurcumin"): a novel strategy for human cancer therapy. J Nanobiotechnol 5:3.
    • (2007) J Nanobiotechnol , vol.5 , pp. 3
    • Bisht, S.1    Feldmann, G.2    Soni, S.3    Ravi, R.4    Karikar, C.5    Maitra, A.6
  • 21
    • 0345118903 scopus 로고    scopus 로고
    • Multidrug resistance protein-6 (MRP6) in human dermal fibroblasts. Comparison between cells from normal subjects and from Pseudoxanthoma elasticum patients
    • Boraldi, F., Quaglino, D., Croce, M. A., Garcia Fernandez, M. I., Tiozzo, R., Gheduzzi, D., et al. (2003). Multidrug resistance protein-6 (MRP6) in human dermal fibroblasts. Comparison between cells from normal subjects and from Pseudoxanthoma elasticum patients. Matrix Biol 22:491-500.
    • (2003) Matrix Biol , vol.22 , pp. 491-500
    • Boraldi, F.1    Quaglino, D.2    Croce, M.A.3    Garcia Fernandez, M.I.4    Tiozzo, R.5    Gheduzzi, D.6
  • 22
    • 0036074018 scopus 로고    scopus 로고
    • Mammalian ABC transporters in health and disease
    • Borst, P., Elferink, R. O. (2002). Mammalian ABC transporters in health and disease. Annu Rev Biochem 71:537-592.
    • (2002) Annu Rev Biochem , vol.71 , pp. 537-592
    • Borst, P.1    Elferink, R.O.2
  • 24
    • 0034674901 scopus 로고    scopus 로고
    • A family of drug transporters: The multidrug resistance-associated proteins
    • Borst, P., Evers, R., Kool, M., Wijnholds, J. (2000). A family of drug transporters: the multidrug resistance-associated proteins. J Natl Cancer Inst 92:1295-1302.
    • (2000) J Natl Cancer Inst , vol.92 , pp. 1295-1302
    • Borst, P.1    Evers, R.2    Kool, M.3    Wijnholds, J.4
  • 25
    • 0036720280 scopus 로고    scopus 로고
    • Recent advances in the discovery of flavonoids and analogs with high- affinity binding to P-glycoprotein responsible for cancer cell multidrug resistance
    • Boumendjel, A., Di Pietro, A., Dumontet, C., Barron, D. (2002). Recent advances in the discovery of flavonoids and analogs with high- affinity binding to P-glycoprotein responsible for cancer cell multidrug resistance. Med Res Rev 22:512-529.
    • (2002) Med Res Rev , vol.22 , pp. 512-529
    • Boumendjel, A.1    Di Pietro, A.2    Dumontet, C.3    Barron, D.4
  • 26
    • 33845906363 scopus 로고    scopus 로고
    • The effect of low pH on breast cancer resistance protein (ABCG2)-mediated transport of methotrexate, 7-hydroxymethotrexate, methotrexate diglutamate, folic acid, mitoxantrone, topotecan, and resveratrol in in vitro drug transport models
    • Breedveld, P., Pluim, D., Cipriani, G., Dahlhaus, F., van Eijndhoven, M. A., de Wolf, C. J., et al. (2007). The effect of low pH on breast cancer resistance protein (ABCG2)-mediated transport of methotrexate, 7-hydroxymethotrexate, methotrexate diglutamate, folic acid, mitoxantrone, topotecan, and resveratrol in in vitro drug transport models. Mol Pharmacol 71:240-249.
    • (2007) Mol Pharmacol , vol.71 , pp. 240-249
    • Breedveld, P.1    Pluim, D.2    Cipriani, G.3    Dahlhaus, F.4    Van Eijndhoven, M.A.5    De Wolf, C.J.6
  • 27
    • 16844384057 scopus 로고    scopus 로고
    • The effect of Bcrp1 (Abcg2) on the in vivo pharmacokinetics and brain penetration of imat- inib mesylate (Gleevec): Implications for the use of breast cancer resistance protein and P-glycoprotein inhibitors to enable the brain penetration of imatinib in patients
    • Breedveld, P., Pluim, D., Cipriani, G., Wielinga, P., van Tellingen, O., Schinkel, A. H., et al. (2005). The effect of Bcrp1 (Abcg2) on the in vivo pharmacokinetics and brain penetration of imat- inib mesylate (Gleevec): implications for the use of breast cancer resistance protein and P-glycoprotein inhibitors to enable the brain penetration of imatinib in patients. Cancer Res 65:2577-2582.
    • (2005) Cancer Res , vol.65 , pp. 2577-2582
    • Breedveld, P.1    Pluim, D.2    Cipriani, G.3    Wielinga, P.4    Van Tellingen, O.5    Schinkel, A.H.6
  • 28
    • 1642523398 scopus 로고    scopus 로고
    • Cellular accumulation of dietary anticarcinogenic isothiocyanates is followed by transporter-mediated export as dithiocarbamates
    • Callaway, E. C., Zhang, Y., Chew, W., Chow, H. H. (2004). Cellular accumulation of dietary anticarcinogenic isothiocyanates is followed by transporter-mediated export as dithiocarbamates. Cancer Lett 204:23-31.
    • (2004) Cancer Lett , vol.204 , pp. 23-31
    • Callaway, E.C.1    Zhang, Y.2    Chew, W.3    Chow, H.H.4
  • 29
    • 0031060647 scopus 로고    scopus 로고
    • Inhibition of drug transport by genistein in multidrug-resistant cells expressing P-glycoprotein
    • Castro, A. F., Altenberg, G. A. (1997). Inhibition of drug transport by genistein in multidrug-resistant cells expressing P-glycoprotein. Biochem Pharmacol 53:89-93.
    • (1997) Biochem Pharmacol , vol.53 , pp. 89-93
    • Castro, A.F.1    Altenberg, G.A.2
  • 30
    • 0029997940 scopus 로고    scopus 로고
    • Transport and epithelial secretion of the cardiac glycoside, digoxin, by human intestinal epithelial (Caco-2) cells
    • Cavet, M. E., West, M., Simmons, N. L. (1996). Transport and epithelial secretion of the cardiac glycoside, digoxin, by human intestinal epithelial (Caco-2) cells. Br J Pharmacol 118:1389-1396.
    • (1996) Br J Pharmacol , vol.118 , pp. 1389-1396
    • Cavet, M.E.1    West, M.2    Simmons, N.L.3
  • 31
    • 33748356494 scopus 로고    scopus 로고
    • Modulation of the function of the multidrug resistance-linked ATP-binding cassette transporter ABCG2 by the cancer chemo- preventive agent curcumin
    • Chearwae, W., Shukla, S., Limtrakul, P., Ambudkar, S. V. (2006). Modulation of the function of the multidrug resistance-linked ATP-binding cassette transporter ABCG2 by the cancer chemo- preventive agent curcumin. Mol Cancer Ther 5:1995-2006.
    • (2006) Mol Cancer Ther , vol.5 , pp. 1995-2006
    • Chearwae, W.1    Shukla, S.2    Limtrakul, P.3    Ambudkar, S.V.4
  • 32
    • 57849106304 scopus 로고    scopus 로고
    • An in vitro study of liposomal curcumin: Stability, toxicity, and biological activity in human lymphocytes and Epstein-Barr virus-transformed human B-cells
    • Chen, C., Johnston, T. D., Jeon, H., Gedaly, R., McHugh, P. P., Burke, T. G., et al. (2009). An in vitro study of liposomal curcumin: stability, toxicity, and biological activity in human lymphocytes and Epstein-Barr virus-transformed human B-cells. Int J Pharm 366:133-139.
    • (2009) Int J Pharm , vol.366 , pp. 133-139
    • Chen, C.1    Johnston, T.D.2    Jeon, H.3    Gedaly, R.4    McHugh, P.P.5    Burke, T.G.6
  • 33
    • 19544388778 scopus 로고    scopus 로고
    • Dietary cancer-chemopreventive compounds: From signaling and gene expression to pharmacological effects
    • Chen, C., Kong, A. N. (2005). Dietary cancer-chemopreventive compounds: from signaling and gene expression to pharmacological effects. Trends Pharmacol Sci 26:318-326.
    • (2005) Trends Pharmacol Sci , vol.26 , pp. 318-326
    • Chen, C.1    Kong, A.N.2
  • 34
    • 0031041385 scopus 로고    scopus 로고
    • Multidrug-resistant human sarcoma cells with a mutant P-glycoprotein, altered phenotype, and resistance to cyclosporins
    • Chen, G., Duran, G. E., Steger, K. A., Lacayo, N. J., Jaffrezou, J. P., Dumontet, C., et al. (1997). Multidrug-resistant human sarcoma cells with a mutant P-glycoprotein, altered phenotype, and resistance to cyclosporins. J Bio Chem 272:5974-5982.
    • (1997) J Bio Chem , vol.272 , pp. 5974-5982
    • Chen, G.1    Duran, G.E.2    Steger, K.A.3    Lacayo, N.J.4    Jaffrezou, J.P.5    Dumontet, C.6
  • 35
    • 0032946239 scopus 로고    scopus 로고
    • ATP-dependent efflux of CPT-11 and SN-38 by the multidrug resistance protein (MRP) and its inhibition by PAK- 104P
    • Chen, Z-S., Furukawa, T., Sumizawa, T., Ono, K., Ueda, K., Seto, K., et al. (1999). ATP-dependent efflux of CPT-11 and SN-38 by the multidrug resistance protein (MRP) and its inhibition by PAK- 104P. Mol Pharmacol 55:921-928.
    • (1999) Mol Pharmacol , vol.55 , pp. 921-928
    • Chen, Z.-S.1    Furukawa, T.2    Sumizawa, T.3    Ono, K.4    Ueda, K.5    Seto, K.6
  • 36
    • 0035823559 scopus 로고    scopus 로고
    • Transport of cyclic nucleotides and estradiol 17-beta-D-glucuronide by multidrug resistance protein 4. Resistance to 6-mercaptopurine and 6-thioguanine
    • Chen, Z. S., Lee, K., Kruh, G. D. (2001). Transport of cyclic nucleotides and estradiol 17-beta-D-glucuronide by multidrug resistance protein 4. Resistance to 6-mercaptopurine and 6-thioguanine. J Bio Chem 276:33747-33754.
    • (2001) J Bio Chem , vol.276 , pp. 33747-33754
    • Chen, Z.S.1    Lee, K.2    Kruh, G.D.3
  • 37
    • 0036137072 scopus 로고    scopus 로고
    • Organ distribution of multidrug resistance proteins 1, 2, and 3 (Mrp1, 2, and 3) mRNA and hepatic induction of Mrp3 by constitutive androstane receptor activators in rats
    • Cherrington, N. J., Hartley, D. P., Li, N., Johnson, D. R., Klaassen, C. D. (2002). Organ distribution of multidrug resistance proteins 1, 2, and 3 (Mrp1, 2, and 3) mRNA and hepatic induction of Mrp3 by constitutive androstane receptor activators in rats. J Pharmacol Exp Ther 300:97-104.
    • (2002) J Pharmacol Exp Ther , vol.300 , pp. 97-104
    • Cherrington, N.J.1    Hartley, D.P.2    Li, N.3    Johnson, D.R.4    Klaassen, C.D.5
  • 38
    • 36849021582 scopus 로고    scopus 로고
    • Curcumin downregulates the multidrug-resistance mdrib gene by inhibiting the PI3K/Akt/NF kappa B pathway
    • Choi, B. H., Kim, C. G., Lim, Y., Shin, S. Y., Lee, Y. H. (2008). Curcumin downregulates the multidrug-resistance mdrib gene by inhibiting the PI3K/Akt/NF kappa B pathway. Cancer Lett 259:111-118.
    • (2008) Cancer Lett , vol.259 , pp. 111-118
    • Choi, B.H.1    Kim, C.G.2    Lim, Y.3    Shin, S.Y.4    Lee, Y.H.5
  • 39
    • 1842789744 scopus 로고    scopus 로고
    • Enhanced bioavailability of paclitaxel after oral coadministration with flavone in rats
    • Choi, J. S., Choi, H. K., Shin, S. C. (2004a). Enhanced bioavailability of paclitaxel after oral coadministration with flavone in rats. Int J Pharm 275:165-170.
    • (2004) Int J Pharm , vol.275 , pp. 165-170
    • Choi, J.S.1    Choi, H.K.2    Shin, S.C.3
  • 40
    • 1442359716 scopus 로고    scopus 로고
    • Enhanced paclitaxel bio- availability after oral administration of paclitaxel or prodrug to rats pretreated with quercetin
    • Choi, J. S., Jo, B. W., Kim, Y. C. (2004b). Enhanced paclitaxel bio- availability after oral administration of paclitaxel or prodrug to rats pretreated with quercetin. Eur J Pharm Biopharm 57: 313-318.
    • (2004) Eur J Pharm Biopharm , vol.57 , pp. 313-318
    • Choi, J.S.1    Jo, B.W.2    Kim, Y.C.3
  • 41
    • 13844256394 scopus 로고    scopus 로고
    • Enhanced paclitaxel bioavailability after oral coadministration of paclitaxel prodrug with naringin to rats
    • Choi, J. S., Shin, S. C. (2005). Enhanced paclitaxel bioavailability after oral coadministration of paclitaxel prodrug with naringin to rats. Int J Pharm 292:149-156.
    • (2005) Int J Pharm , vol.292 , pp. 149-156
    • Choi, J.S.1    Shin, S.C.2
  • 42
    • 7144259744 scopus 로고    scopus 로고
    • The bisbenzylisoquinoline alkaloids, tetrandine and fangchinoline, enhance the cytotoxicity of multidrug resistance- related drugs via modulation of P-glycoprotein
    • Choi, S. U., Park, S. H., Kim, K. H., Choi, E. J., Kim, S., Park, W. K., et al. (1998). The bisbenzylisoquinoline alkaloids, tetrandine and fangchinoline, enhance the cytotoxicity of multidrug resistance- related drugs via modulation of P-glycoprotein. Anticancer Drugs 9:255-261.
    • (1998) Anticancer Drugs , vol.9 , pp. 255-261
    • Choi, S.U.1    Park, S.H.2    Kim, K.H.3    Choi, E.J.4    Kim, S.5    Park, W.K.6
  • 43
    • 0030041159 scopus 로고    scopus 로고
    • Reversal of multidrug resistance in vivo by dietary administration of the phytochemical indole-3 carbinol
    • Christensen, J., LeBlanc, G. (1996). Reversal of multidrug resistance in vivo by dietary administration of the phytochemical indole-3 -carbinol. Cancer Res 56:574-581.
    • (1996) Cancer Res , vol.56 , pp. 574-581
    • Christensen, J.1    Leblanc, G.2
  • 44
    • 1642330416 scopus 로고    scopus 로고
    • Transport of ethinylestradiol glucuronide and ethi- nylestradiol sulfate by the multidrug-resistance proteins MRP1, MRP2, and MRP3
    • Chu, X. Y., Huskey, S. E., Braun, M. P., Sarkadi, B., Evans, D. C., Evers, R. (2004). Transport of ethinylestradiol glucuronide and ethi- nylestradiol sulfate by the multidrug-resistance proteins MRP1, MRP2, and MRP3. J Pharmacol Exp Ther 309:156-164.
    • (2004) J Pharmacol Exp Ther , vol.309 , pp. 156-164
    • Chu, X.Y.1    Huskey, S.E.2    Braun, M.P.3    Sarkadi, B.4    Evans, D.C.5    Evers, R.6
  • 45
    • 2342644918 scopus 로고    scopus 로고
    • Expression, upregulation, and transport activity of the multidrug-resistance protein Abcg2 at the mouse blood-brain barrier
    • Cisternino, S., Mercier, C., Bourasset, F., Roux, F., Scherrmann, J. M. (2004). Expression, upregulation, and transport activity of the multidrug-resistance protein Abcg2 at the mouse blood-brain barrier. Cancer Res 64:3296-3301.
    • (2004) Cancer Res , vol.64 , pp. 3296-3301
    • Cisternino, S.1    Mercier, C.2    Bourasset, F.3    Roux, F.4    Scherrmann, J.M.5
  • 46
    • 33750478648 scopus 로고    scopus 로고
    • Multiple drug-binding sites on the R482G isoform of the ABCG2 transporter
    • Clark, R., Kerr, I. D., Callaghan, R. (2006). Multiple drug-binding sites on the R482G isoform of the ABCG2 transporter. Br J Pharmacol 149:506-515.
    • (2006) Br J Pharmacol , vol.149 , pp. 506-515
    • Clark, R.1    Kerr, I.D.2    Callaghan, R.3
  • 47
    • 0027095653 scopus 로고
    • Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line
    • Cole, S. P. C., Bhardwaj, G., Gerlach, J. H., Mackie, J. E., Grant, C. E., Almquist, K. C. (1992). Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line. Science 258:1650-1654.
    • (1992) Science , vol.258 , pp. 1650-1654
    • Cole, S.P.C.1    Bhardwaj, G.2    Gerlach, J.H.3    MacKie, J.E.4    Grant, C.E.5    Almquist, K.C.6
  • 48
    • 0032589932 scopus 로고    scopus 로고
    • Modulation of the permeability of H2 receptor antagonists, cimetidine and ranitidine, by P-glycoprotein in rat intestine and the human colonic cell line Caco-2
    • Collett, A., Higgs, N. B., Sims, E., Rowland, M., Warhurst, G. (1999). Modulation of the permeability of H2 receptor antagonists, cimetidine and ranitidine, by P-glycoprotein in rat intestine and the human colonic cell line Caco-2. J Pharmacol Exp Ther 288:171-178.
    • (1999) J Pharmacol Exp Ther , vol.288 , pp. 171-178
    • Collett, A.1    Higgs, N.B.2    Sims, E.3    Rowland, M.4    Warhurst, G.5
  • 49
    • 0032544087 scopus 로고    scopus 로고
    • Flavonoids: A class of modulators with bifunc- tional interactions at vicinal ATP- and steroid-binding sites on mouse P-glycoprotein
    • Conseil, G., Baubichon-Cortay, H., Dayan, G., Jault, J. M., Barron, D., Di Pietro, A. (1998). Flavonoids: a class of modulators with bifunc- tional interactions at vicinal ATP- and steroid-binding sites on mouse P-glycoprotein. Proc Natl Acad Sci U S A 95:9831-9836.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 9831-9836
    • Conseil, G.1    Baubichon-Cortay, H.2    Dayan, G.3    Jault, J.M.4    Barron, D.5    Di Pietro, A.6
  • 51
    • 0038155173 scopus 로고    scopus 로고
    • Jatrophane diterpenes as P-glycoprotein inhibitors. First insights of structure-activity relationships and discovery of a new, powerful lead
    • Corea, G., Fattorusso, E., Lanzotti, V., Taglialatela-Scafati, O., Appendino, G., Ballero, M., et al. (2003). Jatrophane diterpenes as P-glycoprotein inhibitors. First insights of structure-activity relationships and discovery of a new, powerful lead. J Med Chem 46:3395-3402.
    • (2003) J Med Chem , vol.46 , pp. 3395-3402
    • Corea, G.1    Fattorusso, E.2    Lanzotti, V.3    Taglialatela-Scafati, O.4    Appendino, G.5    Ballero, M.6
  • 52
    • 0028172728 scopus 로고
    • Modulation of adriamycin accumulation and efflux by flavonoids in HCT-15 colon cells Activation of P-glycoprotein as a putative mechanism
    • Critchfield, J. W., Welsh, C. J., Phang, J. M., Yeh, G. C. (1994). Modulation of adriamycin accumulation and efflux by flavonoids in HCT-15 colon cells. Activation of P-glycoprotein as a putative mechanism. Biochem Pharmacol 48:1437-1445.
    • (1994) Biochem Pharmacol , vol.48 , pp. 1437-1445
    • Critchfield, J.W.1    Welsh, C.J.2    Phang, J.M.3    Yeh, G.C.4
  • 53
    • 62749095208 scopus 로고    scopus 로고
    • Enhancement of oral absorption of curcumin by self-microemul- sifying drug delivery systems
    • Cui, J., Yu, B., Zhao, Y., Zhu, W., Li, H., Lou, H., et al. (2009). Enhancement of oral absorption of curcumin by self-microemul- sifying drug delivery systems. Int J Pharm 371:148-155.
    • (2009) Int J Pharm , vol.371 , pp. 148-155
    • Cui, J.1    Yu, B.2    Zhao, Y.3    Zhu, W.4    Li, H.5    Lou, H.6
  • 54
    • 59949099425 scopus 로고    scopus 로고
    • Expression and transcriptional regulation of ABC transporters and cytochromes P450 in hCMEC/D3 human cerebral microvascular endothelial cells
    • Dauchy, S., Miller, F., Couraud, P. O., Weaver, R. J., Weksler, B., Romero, I. A., et al. (2009). Expression and transcriptional regulation of ABC transporters and cytochromes P450 in hCMEC/D3 human cerebral microvascular endothelial cells. Biochem Pharmacol 77:897-909.
    • (2009) Biochem Pharmacol , vol.77 , pp. 897-909
    • Dauchy, S.1    Miller, F.2    Couraud, P.O.3    Weaver, R.J.4    Weksler, B.5    Romero, I.A.6
  • 55
    • 0029948519 scopus 로고    scopus 로고
    • Recombinant N-terminal nucleotide-binding domain from mouse P-glycoprotein. Overexpression, purification, and role of cysteine 430
    • Dayan, G., Baubichon-Cortay, H., Jault, J. M., Cortay, J. C., Deleage, G., Di Pietro, A. (1996). Recombinant N-terminal nucleotide-binding domain from mouse P-glycoprotein. Overexpression, purification, and role of cysteine 430. J Biol Chem 271:11652-11658.
    • (1996) J Biol Chem , vol.271 , pp. 11652-11658
    • Dayan, G.1    Baubichon-Cortay, H.2    Jault, J.M.3    Cortay, J.C.4    Deleage, G.5    Di Pietro, A.6
  • 56
    • 0032695270 scopus 로고    scopus 로고
    • Reversal of resistance by GF120918 in cell lines expressing the ABC half-transporter, MXR
    • de Bruin, M., Miyake, K., Litman, T., Robey, R., Bates, S. E. (1999). Reversal of resistance by GF120918 in cell lines expressing the ABC half-transporter, MXR. Cancer Lett 146:117-126.
    • (1999) Cancer Lett , vol.146 , pp. 117-126
    • De Bruin, M.1    Miyake, K.2    Litman, T.3    Robey, R.4    Bates, S.E.5
  • 57
    • 35348973560 scopus 로고    scopus 로고
    • Grapefruit juice-drug interactions: Grapefruit juice and its components inhibit p-glycoprotein (ABCB1)-mediated transport of talinolol in Caco-2 cells
    • De Castro, W. V., Mertens-Talcott, S., Derendorf, H., Butterweck, V. (2007). Grapefruit juice-drug interactions: grapefruit juice and its components inhibit p-glycoprotein (ABCB1)-mediated transport of talinolol in Caco-2 cells. J Pharm Sci 96:2808-2817.
    • (2007) J Pharm Sci , vol.96 , pp. 2808-2817
    • De Castro, W.V.1    Mertens-Talcott, S.2    Derendorf, H.3    Butterweck, V.4
  • 58
    • 54049137262 scopus 로고    scopus 로고
    • Contribution of the drug transporter, ABCG2 (breast cancer resistance protein), to resistance against anticancer nucleosides
    • de Wolf, C., Jansen, R., Yamaguchi, H., de Haas, M., van de Wetering, K., Wijnholds, J., et al. (2008). Contribution of the drug transporter, ABCG2 (breast cancer resistance protein), to resistance against anticancer nucleosides. Mol Cancer Ther 7:3092-3102.
    • (2008) Mol Cancer Ther , vol.7 , pp. 3092-3102
    • De Wolf, C.1    Jansen, R.2    Yamaguchi, H.3    De Haas, M.4    Van De Wetering, K.5    Wijnholds, J.6
  • 59
    • 0034819420 scopus 로고    scopus 로고
    • Carotenoid composition in the fruits of red paprika (Capsicum annuum var lycopersiciforme rubrum) during ripening; Biosynthesis of caro- tenoids in red paprika
    • Deli, J., Molnar, P., Matus, Z., Toth, G. (2001). Carotenoid composition in the fruits of red paprika (Capsicum annuum var. lycopersiciforme rubrum) during ripening; biosynthesis of caro- tenoids in red paprika. J Agric Food Chem 49:1517-1523.
    • (2001) J Agric Food Chem , vol.49 , pp. 1517-1523
    • Deli, J.1    Molnar, P.2    Matus, Z.3    Toth, G.4
  • 60
  • 61
    • 5144232445 scopus 로고    scopus 로고
    • Diallyl disulfide, a chemopreventive agent in garlic, induces multidrug-resistance-associated protein 2 expression
    • Demeule, M., Brossard, M., Turcotte, S., Regina, A., Jodoin, J., Beliveau, R. (2004). Diallyl disulfide, a chemopreventive agent in garlic, induces multidrug-resistance-associated protein 2 expression. Biochem Biophys Res Commun 324:937-945.
    • (2004) Biochem Biophys Res Commun , vol.324 , pp. 937-945
    • Demeule, M.1    Brossard, M.2    Turcotte, S.3    Regina, A.4    Jodoin, J.5    Beliveau, R.6
  • 63
    • 0035037554 scopus 로고    scopus 로고
    • Placental transfer of the soy isoflavone, genistein, following dietary and gavage administration to Sprague-Dawley rats
    • Doerge, D. R., Churchwell, M. I., Chang, H. C., Newbold, R. R., Delclos, K. B. (2001). Placental transfer of the soy isoflavone, genistein, following dietary and gavage administration to Sprague-Dawley rats. Reprod Toxicol 15:105-110.
    • (2001) Reprod Toxicol , vol.15 , pp. 105-110
    • Doerge, D.R.1    Churchwell, M.I.2    Chang, H.C.3    Newbold, R.R.4    Delclos, K.B.5
  • 65
    • 9544240355 scopus 로고    scopus 로고
    • Involvement of P-glycoprotein in the transmembrane transport of interleukin-2 (IL-2), IL-4, and interferon-gamma in normal human T lymphocytes
    • Drach, J., Gsur, A., Hamilton, G., Zhao, S., Angerler, J., Fiegl, M., et al. (1996). Involvement of P-glycoprotein in the transmembrane transport of interleukin-2 (IL-2), IL-4, and interferon-gamma in normal human T lymphocytes. Blood 88:1747-1754.
    • (1996) Blood , vol.88 , pp. 1747-1754
    • Drach, J.1    Gsur, A.2    Hamilton, G.3    Zhao, S.4    Angerler, J.5    Fiegl, M.6
  • 66
    • 71649106260 scopus 로고    scopus 로고
    • Berry anthocyanins and anthocyanidins exhibit distinct affinities for the efflux transporters BCRP and MDR1
    • Dreiseitel, A., Oosterhuis, B., Vukman, K. V., Schreier, P., Oehme, A., Locher, S., et al. (2009). Berry anthocyanins and anthocyanidins exhibit distinct affinities for the efflux transporters BCRP and MDR1. Br J Pharmacol 158:1942-1950.
    • (2009) Br J Pharmacol , vol.158 , pp. 1942-1950
    • Dreiseitel, A.1    Oosterhuis, B.2    Vukman, K.V.3    Schreier, P.4    Oehme, A.5    Locher, S.6
  • 67
    • 0042950000 scopus 로고    scopus 로고
    • Coordinate induction of both cytochrome P4503A and MDR1 by St John's wort in healthy subjects
    • Dresser, G. K., Schwarz, U. I., Wilkinson, G. R., Kim, R. B. (2003). Coordinate induction of both cytochrome P4503A and MDR1 by St John's wort in healthy subjects. Clin Pharmacol Ther 73: 41-50.
    • (2003) Clin Pharmacol Ther , vol.73 , pp. 41-50
    • Dresser, G.K.1    Schwarz, U.I.2    Wilkinson, G.R.3    Kim, R.B.4
  • 68
    • 0029079452 scopus 로고
    • Reversal of multidrug-resistance phenotype by surfactants: Relationship to membrane-lipid fluidity
    • Dudeja, P., Anderson, K., Harris, J., Buckingham, L., Coon, J. (1995). Reversal of multidrug-resistance phenotype by surfactants: relationship to membrane-lipid fluidity. Arch Biochem Biophys 319:309-315.
    • (1995) Arch Biochem Biophys , vol.319 , pp. 309-315
    • Dudeja, P.1    Anderson, K.2    Harris, J.3    Buckingham, L.4    Coon, J.5
  • 70
    • 34447505041 scopus 로고    scopus 로고
    • Berry phytochemicals, genomic stability, and cancer: Evidence for chemoprotection at several stages in the carcinogenic process
    • Duthie, S. J. (2007). Berry phytochemicals, genomic stability, and cancer: evidence for chemoprotection at several stages in the carcinogenic process. Mol Nutr Food Res 51:665-674.
    • (2007) Mol Nutr Food Res , vol.51 , pp. 665-674
    • Duthie, S.J.1
  • 71
    • 27144483358 scopus 로고    scopus 로고
    • Identification of BCRP as transporter of benzo[a]pyrene conjugates metabolically formed in Caco-2 cells and its induction by Ah-receptor agonists
    • Ebert, B., Seidel, A., Lampen, A. (2005). Identification of BCRP as transporter of benzo[a]pyrene conjugates metabolically formed in Caco-2 cells and its induction by Ah-receptor agonists. Carcinogenesis 26:1754-1763.
    • (2005) Carcinogenesis , vol.26 , pp. 1754-1763
    • Ebert, B.1    Seidel, A.2    Lampen, A.3
  • 72
    • 33947233105 scopus 로고    scopus 로고
    • Phytochemicals induce breast cancer resistance protein in Caco-2 cells and enhance the transport of benzo[a]pyrene-3-sulfate
    • Ebert, B., Seidel, A., Lampen, A. (2007). Phytochemicals induce breast cancer resistance protein in Caco-2 cells and enhance the transport of benzo[a]pyrene-3-sulfate. Toxicol Sci 96:227-236.
    • (2007) Toxicol Sci , vol.96 , pp. 227-236
    • Ebert, B.1    Seidel, A.2    Lampen, A.3
  • 73
    • 34748926909 scopus 로고    scopus 로고
    • Effect of breast cancer resistance protein (Bcrp/Abcg2) on the disposition of phytoestrogens
    • DOI 10.1124/mol.107.034751
    • Enokizono, J., Kusuhara, H., Sugiyama, Y. (2007). Effect of breast cancer resistance protein (bcrp/abcg2) on the disposition of phytoestrogens. Mol Pharmacol 72:967-975. (Pubitemid 47481419)
    • (2007) Molecular Pharmacology , vol.72 , Issue.4 , pp. 967-975
    • Enokizono, J.1    Kusuhara, H.2    Sugiyama, Y.3
  • 75
    • 33646471830 scopus 로고    scopus 로고
    • ABC drug- transporter expression and functional activity in trophoblast-like cell lines and differentiating primary trophoblast
    • Evseenko, D. A., Paxton, J. W., Keelan, J. A. (2006). ABC drug- transporter expression and functional activity in trophoblast-like cell lines and differentiating primary trophoblast. Am J Physiol Regul Integr Comp Physiol 290:R1357-R1365.
    • (2006) Am J Physiol Regul Integr Comp Physiol , vol.290
    • Evseenko, D.A.1    Paxton, J.W.2    Keelan, J.A.3
  • 77
    • 33645930969 scopus 로고    scopus 로고
    • Localization of the ABCG2 mitoxantrone resistance-associated protein in normal tissues
    • Fetsch, P. A., Abati, A., Litman, T., Morisaki, K., Honjo, Y., Mittal, K., et al. (2006). Localization of the ABCG2 mitoxantrone resistance-associated protein in normal tissues. Cancer Lett 235: 84-92.
    • (2006) Cancer Lett , vol.235 , pp. 84-92
    • Fetsch, P.A.1    Abati, A.2    Litman, T.3    Morisaki, K.4    Honjo, Y.5    Mittal, K.6
  • 78
    • 75149143363 scopus 로고    scopus 로고
    • ABC transporters in cancer: More than just drug efflux pumps
    • Fletcher, J. I., Haber, M., Henderson, M. J., Norris, M. D. (2010). ABC transporters in cancer: more than just drug efflux pumps. Nat Rev Cancer 10:147-156.
    • (2010) Nat Rev Cancer , vol.10 , pp. 147-156
    • Fletcher, J.I.1    Haber, M.2    Henderson, M.J.3    Norris, M.D.4
  • 79
    • 34250379186 scopus 로고    scopus 로고
    • Schisandrol A from Schisandra chinensis reverses P-glycoprotein-mediated multidrug resistance by affecting Pgp- substrate complexes
    • Fong, W. F., Wan, C. K., Zhu, G. Y., Chattopadhyay, A., Dey, S., Zhao, Z., et al. (2007). Schisandrol A from Schisandra chinensis reverses P-glycoprotein-mediated multidrug resistance by affecting Pgp- substrate complexes. Planta Med 73:212-220.
    • (2007) Planta Med , vol.73 , pp. 212-220
    • Fong, W.F.1    Wan, C.K.2    Zhu, G.Y.3    Chattopadhyay, A.4    Dey, S.5    Zhao, Z.6
  • 80
    • 34247646575 scopus 로고    scopus 로고
    • Tariquidar (XR9576): A P-glycoprotein drug efflux pump inhibitor
    • Fox, E., Bates, S. E. (2007). Tariquidar (XR9576): a P-glycoprotein drug efflux pump inhibitor. Exp Rev Anticancer Ther 7: 447-459.
    • (2007) Exp Rev Anticancer Ther , vol.7 , pp. 447-459
    • Fox, E.1    Bates, S.E.2
  • 81
    • 0032710237 scopus 로고    scopus 로고
    • Epithelial transport of anthelmintic ivermectin in a novel model of isolated proximal kidney tubules
    • Fricker, G., Gutmann, H., Droulle, A., Drewe, J., Miller, D. (1999). Epithelial transport of anthelmintic ivermectin in a novel model of isolated proximal kidney tubules. Pharm Res 16: 1570-1575.
    • (1999) Pharm Res , vol.16 , pp. 1570-1575
    • Fricker, G.1    Gutmann, H.2    Droulle, A.3    Drewe, J.4    Miller, D.5
  • 82
    • 67249125471 scopus 로고    scopus 로고
    • Curcumin analogues exhibit enhanced growth suppres- sive activity in human pancreatic cancer cells
    • Friedman, L., Lin, L., Ball, S., Bekaii-Saab, T., Fuchs, J., Li, P. K., et al. (2009) Curcumin analogues exhibit enhanced growth suppres- sive activity in human pancreatic cancer cells. Anticancer Drugs 20:444-449.
    • (2009) Anticancer Drugs , vol.20 , pp. 444-449
    • Friedman, L.1    Lin, L.2    Ball, S.3    Bekaii-Saab, T.4    Fuchs, J.5    Li, P.K.6
  • 83
    • 1642299307 scopus 로고    scopus 로고
    • Characterization of tetrandrine, a potent inhibitor of P- glycoprotein-mediated multidrug resistance
    • Fu, L., Liang, Y., Deng, L., Ding, Y., Chen, L., Ye, Y., et al. (2004). Characterization of tetrandrine, a potent inhibitor of P- glycoprotein-mediated multidrug resistance. Cancer Chemother Pharmacol 53:349-356.
    • (2004) Cancer Chemother Pharmacol , vol.53 , pp. 349-356
    • Fu, L.1    Liang, Y.2    Deng, L.3    Ding, Y.4    Chen, L.5    Ye, Y.6
  • 84
    • 9044252313 scopus 로고    scopus 로고
    • CYP3A-like cytochrome P450- mediated metabolism and polarized efflux of cyclosporin A in Caco-2 cells
    • Gan, L. S., Moseley, M. A., Khosla, B., Augustijns, P. F., Bradshaw, T. P., Hendren, R. W., et al. (1996). CYP3A-like cytochrome P450- mediated metabolism and polarized efflux of cyclosporin A in Caco-2 cells. Drug Metab Dispos 24:344-349.
    • (1996) Drug Metab Dispos , vol.24 , pp. 344-349
    • Gan, L.S.1    Moseley, M.A.2    Khosla, B.3    Augustijns, P.F.4    Bradshaw, T.P.5    Hendren, R.W.6
  • 85
    • 70349176240 scopus 로고    scopus 로고
    • Is resistance useless? Multidrug resistance and collateral sensitivity
    • Hall, M. D., Handley, M. D., Gottesman, M. M. (2009). Is resistance useless? Multidrug resistance and collateral sensitivity. Trends Pharmacol Sci 30:546-556.
    • (2009) Trends Pharmacol Sci , vol.30 , pp. 546-556
    • Hall, M.D.1    Handley, M.D.2    Gottesman, M.M.3
  • 86
    • 46749147175 scopus 로고    scopus 로고
    • In vitro and in vivo evaluation of the effects of piperine on P-gp function and expression
    • Han, Y., Chin, Tan, T. M., Lim, L. Y. (2008). In vitro and in vivo evaluation of the effects of piperine on P-gp function and expression. Toxicol Appl Pharmacol 230:283-289.
    • (2008) Toxicol Appl Pharmacol , vol.230 , pp. 283-289
    • Han, Y.1    Chin Tan, T.M.2    Lim, L.Y.3
  • 87
    • 39849092746 scopus 로고    scopus 로고
    • Sulforaphane and erucin increase MRP1 and MRP2 in human carcinoma cell lines
    • Harris, K. E., Jeffery, E. H. (2008). Sulforaphane and erucin increase MRP1 and MRP2 in human carcinoma cell lines. J Nutr Biochem 19:246-254.
    • (2008) J Nutr Biochem , vol.19 , pp. 246-254
    • Harris, K.E.1    Jeffery, E.H.2
  • 89
    • 0026621245 scopus 로고
    • ABC transporters: From microorganisms to man
    • Higgins, C. F. (1992). ABC transporters: from microorganisms to man. Annu Rev Cell Biol 8:67-113.
    • (1992) Annu Rev Cell Biol , vol.8 , pp. 67-113
    • Higgins, C.F.1
  • 90
    • 34547169521 scopus 로고    scopus 로고
    • Expression of thirty-six drug transporter genes in human intestine, liver, kidney, and organotypic cell lines
    • Hilgendorf, C., Ahlin, G., Seithel, A., Artursson, P., Ungell, A. L., Karlsson, J. (2007). Expression of thirty-six drug transporter genes in human intestine, liver, kidney, and organotypic cell lines. Drug Metab Dispos 35:1333-1340.
    • (2007) Drug Metab Dispos , vol.35 , pp. 1333-1340
    • Hilgendorf, C.1    Ahlin, G.2    Seithel, A.3    Artursson, P.4    Ungell, A.L.5    Karlsson, J.6
  • 92
    • 0141849078 scopus 로고    scopus 로고
    • Involvement of multidrug-resistance-associated proteins in regulating cellular levels of (-)-epigallocatechin-3-gallate and its methyl metabolites
    • Hong, J., Lambert, J. D., Lee, S. H., Sinko, P. J., Yang, C. S. (2003). Involvement of multidrug-resistance-associated proteins in regulating cellular levels of (-)-epigallocatechin-3-gallate and its methyl metabolites. Biochem Biophys Res Commun 310:222-227.
    • (2003) Biochem Biophys Res Commun , vol.310 , pp. 222-227
    • Hong, J.1    Lambert, J.D.2    Lee, S.H.3    Sinko, P.J.4    Yang, C.S.5
  • 93
    • 0033731516 scopus 로고    scopus 로고
    • Function and regulation of ATP-binding cassette transport proteins involved in hepatobiliary transport
    • Hooivelda, G. J. E. J., van Montfoorta, J. E. (2000). Function and regulation of ATP-binding cassette transport proteins involved in hepatobiliary transport. Eur J Pharm Sci 12:13-30.
    • (2000) Eur J Pharm Sci , vol.12 , pp. 13-30
    • Hooivelda, G.J.E.J.1    Van Montfoorta, J.E.2
  • 94
    • 46649098436 scopus 로고    scopus 로고
    • Flavonoids, flavonoid-rich foods, and cardiovascular risk: A meta-analysis of randomized, controlled trials
    • Hooper, L., Kroon, P. A., Rimm, E. B., Cohn, J. S., Harvey, I., Le Cornu, K. A., et al. (2008). Flavonoids, flavonoid-rich foods, and cardiovascular risk: a meta-analysis of randomized, controlled trials. Am J Clin Nutr 88:38-50.
    • (2008) Am J Clin Nutr , vol.88 , pp. 38-50
    • Hooper, L.1    Kroon, P.A.2    Rimm, E.B.3    Cohn, J.S.4    Harvey, I.5    Le Cornu, K.A.6
  • 95
    • 44449088297 scopus 로고    scopus 로고
    • Curcuma drugs and curcumin regulate the expression and function of P-gp in Caco-2 cells in completely opposite ways
    • Hou, X. L., Takahashi, K., Tanaka, K., Tougou, K., Qiu, F., Komatsu, K., et al. (2008). Curcuma drugs and curcumin regulate the expression and function of P-gp in Caco-2 cells in completely opposite ways. Int J Pharm 358:224-229.
    • (2008) Int J Pharm , vol.358 , pp. 224-229
    • Hou, X.L.1    Takahashi, K.2    Tanaka, K.3    Tougou, K.4    Qiu, F.5    Komatsu, K.6
  • 96
    • 1942506722 scopus 로고    scopus 로고
    • Imatinib mesylate is a potent inhibitor of the ABCG2 (BCRP) transporter and reverses resistance to topotecan and SN-38 in vitro
    • Houghton, P. J., Germain, G. S., Harwood, F. C., Schuetz, J. D., Stewart, C. F., Buchdunger, E., et al. (2004). Imatinib mesylate is a potent inhibitor of the ABCG2 (BCRP) transporter and reverses resistance to topotecan and SN-38 in vitro. Cancer Res 64: 2333-2337.
    • (2004) Cancer Res , vol.64 , pp. 2333-2337
    • Houghton, P.J.1    Germain, G.S.2    Harwood, F.C.3    Schuetz, J.D.4    Stewart, C.F.5    Buchdunger, E.6
  • 97
    • 40849145621 scopus 로고    scopus 로고
    • In vitro-to-in vivo prediction of P-glycoprotein-based drug interactions at the human and rodent blood-brain barrier
    • Hsiao, P., Bui, T., Ho, R. J., Unadkat, J. D. (2008). In vitro-to-in vivo prediction of P-glycoprotein-based drug interactions at the human and rodent blood-brain barrier. Drug Metab Dispos 36:481-484.
    • (2008) Drug Metab Dispos , vol.36 , pp. 481-484
    • Hsiao, P.1    Bui, T.2    Ho, R.J.3    Unadkat, J.D.4
  • 98
    • 0037159933 scopus 로고    scopus 로고
    • Multidrug resistance protein 2 (MRP2) transports HIV protease inhibitors, and transport can be enhanced by other drugs
    • Huisman, M. T., Smit, J. W., Crommentuyn, K. M., Zelcer, N., Wiltshire, H. R., Beijnen, J. H., et al. (2002). Multidrug resistance protein 2 (MRP2) transports HIV protease inhibitors, and transport can be enhanced by other drugs. AIDS 16:2295-2301.
    • (2002) AIDS , vol.16 , pp. 2295-2301
    • Huisman, M.T.1    Smit, J.W.2    Crommentuyn, K.M.3    Zelcer, N.4    Wiltshire, H.R.5    Beijnen, J.H.6
  • 99
    • 37549068911 scopus 로고    scopus 로고
    • The breast cancer resistance protein transporter, ABCG2, is expressed in the human kidney proximal tubule apical membrane
    • Huls, M., Brown, C. D., Windass, A. S., Sayer, R., van den Heuvel, J. J., Heemskerk, S., et al. (2008). The breast cancer resistance protein transporter, ABCG2, is expressed in the human kidney proximal tubule apical membrane. Kidney Int 73:220-225.
    • (2008) Kidney Int , vol.73 , pp. 220-225
    • Huls, M.1    Brown, C.D.2    Windass, A.S.3    Sayer, R.4    Van Den Heuvel, J.J.5    Heemskerk, S.6
  • 100
    • 59149089885 scopus 로고    scopus 로고
    • The role of ATP-binding cassette transporters in tissue defense and organ regeneration
    • Huls, M., Russel, F. G., Masereeuw, R. (2009). The role of ATP-binding cassette transporters in tissue defense and organ regeneration. J Pharmacol Exp Ther 328:3-9.
    • (2009) J Pharmacol Exp Ther , vol.328 , pp. 3-9
    • Huls, M.1    Russel, F.G.2    Masereeuw, R.3
  • 101
    • 0025964988 scopus 로고
    • Interaction of organic chemicals with P-glycoprotein in the adrenal gland, kidney, and a multidrug- resistant KB cell
    • Ichikawa, M., Yoshimura, A., Sumizawa, T., Shudo, N., Kuwazuru, Y., Furukawa, T., et al. (1991). Interaction of organic chemicals with P-glycoprotein in the adrenal gland, kidney, and a multidrug- resistant KB cell. J Bio Chem 266:903-908.
    • (1991) J Bio Chem , vol.266 , pp. 903-908
    • Ichikawa, M.1    Yoshimura, A.2    Sumizawa, T.3    Shudo, N.4    Kuwazuru, Y.5    Furukawa, T.6
  • 102
    • 0042856460 scopus 로고    scopus 로고
    • Breast cancer resistance protein exports sulfated estrogens but not free estrogens
    • Imai, Y., Asada, S., Tsukahara, S., Ishikawa, E., Tsuruo, T., Sugimoto, Y. (2003). Breast cancer resistance protein exports sulfated estrogens but not free estrogens. Mol Pharmacol 64:610-618.
    • (2003) Mol Pharmacol , vol.64 , pp. 610-618
    • Imai, Y.1    Asada, S.2    Tsukahara, S.3    Ishikawa, E.4    Tsuruo, T.5    Sugimoto, Y.6
  • 103
    • 3042569646 scopus 로고    scopus 로고
    • Phytoestrogens/ flavonoids reverse breast cancer resistance protein/ABCG2- mediated multidrug resistance
    • Imai, Y., Tsukahara, S., Asada, S., Sugimoto, Y. (2004). Phytoestrogens/ flavonoids reverse breast cancer resistance protein/ABCG2- mediated multidrug resistance. Cancer Res 64:4346-4352.
    • (2004) Cancer Res , vol.64 , pp. 4346-4352
    • Imai, Y.1    Tsukahara, S.2    Asada, S.3    Sugimoto, Y.4
  • 104
    • 0034811602 scopus 로고    scopus 로고
    • Correlation of gene expression of ten drug-efflux proteins of the ATP-binding cassette transporter family in normal human jejunum and in human intestinal epithelial Caco-2 cell monolayers
    • Jan, T., Hans, T., Greger, L., Curt, E. (2001). Correlation of gene expression of ten drug-efflux proteins of the ATP-binding cassette transporter family in normal human jejunum and in human intestinal epithelial Caco-2 cell monolayers. J Pharmacol Exp Ther 299:164-170.
    • (2001) J Pharmacol Exp Ther , vol.299 , pp. 164-170
    • Jan, T.1    Hans, T.2    Greger, L.3    Curt, E.4
  • 105
    • 0034730755 scopus 로고    scopus 로고
    • The multidrug resistance protein 5 functions as an ATP-dependent export pump for cyclic nucleotides
    • Jedlitschky, G., Burchell, B., Keppler, D. (2000). The multidrug resistance protein 5 functions as an ATP-dependent export pump for cyclic nucleotides. J Bio Chem 275:30069-30074.
    • (2000) J Bio Chem , vol.275 , pp. 30069-30074
    • Jedlitschky, G.1    Burchell, B.2    Keppler, D.3
  • 106
    • 22144497802 scopus 로고    scopus 로고
    • Transport of dietary phenethyl isothio- cyanate is mediated by multidrug resistance protein 2 but not P-glycoprotein
    • Ji, Y., Morris, M. E. (2005). Transport of dietary phenethyl isothio- cyanate is mediated by multidrug resistance protein 2 but not P-glycoprotein. Biochem Pharmacol 70:640-647.
    • (2005) Biochem Pharmacol , vol.70 , pp. 640-647
    • Ji, Y.1    Morris, M.E.2
  • 107
    • 12144264443 scopus 로고    scopus 로고
    • Reversal of multidrug resistance of cancer through inhibition of P-glycoprotein by 5-bromotetrandrine
    • DOI 10.1007/s00280-004-0868-0
    • Jin, J., Wang, F. P., Wei, H., Liu, G. (2005). Reversal of multidrug resistance of cancer through inhibition of P-glycoprotein by 5-bromotetrandrine. Cancer Chemother Pharmacol 55: 179-188. (Pubitemid 40110061)
    • (2005) Cancer Chemotherapy and Pharmacology , vol.55 , Issue.2 , pp. 179-188
    • Jin, J.1    Wang, F.-P.2    Wei, H.3    Liu, G.4
  • 108
    • 0037196568 scopus 로고    scopus 로고
    • Inhibition of the multidrug resistance P-glycoprotein activity by green tea polyphenols
    • Jodoin, J., Demeule, M., Beliveau, R. (2002). Inhibition of the multidrug resistance P-glycoprotein activity by green tea polyphenols. Biochim Biophys Acta 1542:149-159.
    • (2002) Biochim Biophys Acta , vol.1542 , pp. 149-159
    • Jodoin, J.1    Demeule, M.2    Beliveau, R.3
  • 109
    • 14644409841 scopus 로고    scopus 로고
    • The breast cancer resistance protein, BCRP (ABCG2), concentrates drugs and carcinogenic xeno- toxins into milk
    • Jonker, J. W., Merino, G., Musters, S., van Herwaarden, A. E., Bolscher, E., Wagenaar, E., et al. (2005). The breast cancer resistance protein, BCRP (ABCG2), concentrates drugs and carcinogenic xeno- toxins into milk. Nat Med 11:127-129.
    • (2005) Nat Med , vol.11 , pp. 127-129
    • Jonker, J.W.1    Merino, G.2    Musters, S.3    Van Herwaarden, A.E.4    Bolscher, E.5    Wagenaar, E.6
  • 110
    • 0034684120 scopus 로고    scopus 로고
    • Role of breast cancer resistance protein in the bioavailability and fetal penetration of topotecan
    • Jonker, J. W., Smit, J. W. (2000). Role of breast cancer resistance protein in the bioavailability and fetal penetration of topotecan. J Natl Cancer Inst 92:1651-1656.
    • (2000) J Natl Cancer Inst , vol.92 , pp. 1651-1656
    • Jonker, J.W.1    Smit, J.W.2
  • 111
    • 34250363135 scopus 로고    scopus 로고
    • Unexpected effect of concomitantly administered curcumin on the pharmacokinetics of talinolol in healthy Chinese volunteers
    • Juan, H., Terhaag, B., Cong, Z., Bi-Kui, Z., Rong-Hua, Z., Feng, W., et al. (2007). Unexpected effect of concomitantly administered curcumin on the pharmacokinetics of talinolol in healthy Chinese volunteers. Eur J Clin Pharmacol 63:663-668.
    • (2007) Eur J Clin Pharmacol , vol.63 , pp. 663-668
    • Juan, H.1    Terhaag, B.2    Cong, Z.3    Bi-Kui, Z.4    Rong-Hua, Z.5    Feng, W.6
  • 113
    • 0031043119 scopus 로고    scopus 로고
    • The role of multidrug-resistance-associated protein (MRP) expression in multidrug resistance
    • Kavallaris, M. (1997). The role of multidrug-resistance-associated protein (MRP) expression in multidrug resistance. Anticancer Drugs 8:17-25.
    • (1997) Anticancer Drugs , vol.8 , pp. 17-25
    • Kavallaris, M.1
  • 114
    • 0033652766 scopus 로고    scopus 로고
    • Impaired protein maturation of the conjugate export pump multidrug-resistance protein 2 as a consequence of a deletion mutation in Dubin-Johnson syndrome
    • Keitel, V., Kartenbeck, J., Nies, A. T., Spring, H., Brom, M., Keppler, D. (2000). Impaired protein maturation of the conjugate export pump multidrug-resistance protein 2 as a consequence of a deletion mutation in Dubin-Johnson syndrome. Hepatology 32:1317-1328.
    • (2000) Hepatology , vol.32 , pp. 1317-1328
    • Keitel, V.1    Kartenbeck, J.2    Nies, A.T.3    Spring, H.4    Brom, M.5    Keppler, D.6
  • 115
    • 56149125452 scopus 로고    scopus 로고
    • Apoptosis by dietary agents for prevention and treatment of cancer
    • Khan, N., Adhami, V. M., Mukhtar, H. (2008). Apoptosis by dietary agents for prevention and treatment of cancer. Biochem Pharmacol 76:1333-1339.
    • (2008) Biochem Pharmacol , vol.76 , pp. 1333-1339
    • Khan, N.1    Adhami, V.M.2    Mukhtar, H.3
  • 116
    • 68849107630 scopus 로고    scopus 로고
    • Short-term effect of quercetin on the pharmacokinetics of fexofenadine, a substrate of P-glycoprotein, in healthy volunteers
    • Kim, K., Park, P., Park, J. (2009). Short-term effect of quercetin on the pharmacokinetics of fexofenadine, a substrate of P-glycoprotein, in healthy volunteers. Eur J Clin Pharmacol 65:609-614.
    • (2009) Eur J Clin Pharmacol , vol.65 , pp. 609-614
    • Kim, K.1    Park, P.2    Park, J.3
  • 117
    • 0037212768 scopus 로고    scopus 로고
    • Reversal of P-glycoprotein-mediated multidrug resistance by ginsenoside Rg(3)
    • Kim, S. W., Kwon, H. Y., Chi, D. W., Shim, J. H., Park, J. D., Lee, Y. H., et al. (2003). Reversal of P-glycoprotein-mediated multidrug resistance by ginsenoside Rg(3). Biochem Pharmacol 65: 75-82.
    • (2003) Biochem Pharmacol , vol.65 , pp. 75-82
    • Kim, S.W.1    Kwon, H.Y.2    Chi, D.W.3    Shim, J.H.4    Park, J.D.5    Lee, Y.H.6
  • 119
    • 35349005744 scopus 로고    scopus 로고
    • Inhibitory effects of ginsenosides and their hydro- lyzed metabolites on daunorubicin transport in KB-C2 cells
    • Kitagawa, S., Takahashi, T., Nabekura, T., Tachikawa, E., Hasegawa, H. (2007b). Inhibitory effects of ginsenosides and their hydro- lyzed metabolites on daunorubicin transport in KB-C2 cells. Biol Pharm Bull 30:1979-1981.
    • (2007) Biol Pharm Bull , vol.30 , pp. 1979-1981
    • Kitagawa, S.1    Takahashi, T.2    Nabekura, T.3    Tachikawa, E.4    Hasegawa, H.5
  • 120
    • 77949398878 scopus 로고    scopus 로고
    • Xenobiotic, bile Acid, and cholesterol transporters: Function and regulation
    • Klaassen, C. D., Aleksunes, L. M. (2010). Xenobiotic, bile Acid, and cholesterol transporters: function and regulation. Pharmacol Rev 62:1-96.
    • (2010) Pharmacol Rev , vol.62 , pp. 1-96
    • Klaassen, C.D.1    Aleksunes, L.M.2
  • 121
    • 0030800078 scopus 로고    scopus 로고
    • Quantitative structure-activity relationship of multidrug-resistance reversal agents
    • Klopman, G., Shi, L., Ramu, A. (1997). Quantitative structure-activity relationship of multidrug-resistance reversal agents. Mol Pharmacol 52:323-334.
    • (1997) Mol Pharmacol , vol.52 , pp. 323-334
    • Klopman, G.1    Shi, L.2    Ramu, A.3
  • 122
    • 20944433769 scopus 로고    scopus 로고
    • Lack of improvement of oral absorption of ME3277 by prodrug formation is ascribed to the intestinal efflux mediated by breast cancer resistant protein (BCRP/ABCG2)
    • Kondo, C., Onuki, R., Kusuhara, H., Suzuki, H., Suzuki, M., Okudaira, N., et al. (2005). Lack of improvement of oral absorption of ME3277 by prodrug formation is ascribed to the intestinal efflux mediated by breast cancer resistant protein (BCRP/ABCG2). Pharm Res 22:613-618.
    • (2005) Pharm Res , vol.22 , pp. 613-618
    • Kondo, C.1    Onuki, R.2    Kusuhara, H.3    Suzuki, H.4    Suzuki, M.5    Okudaira, N.6
  • 123
    • 0030841332 scopus 로고    scopus 로고
    • Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines
    • Kool, M., Dehaas, M., Scheffer, G. L., Scheper, R. J., Vaneijk, M. J. T., Juijn, J. A., et al. (1997). Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines. Cancer Res 57:3537-3547.
    • (1997) Cancer Res , vol.57 , pp. 3537-3547
    • Kool, M.1    Dehaas, M.2    Scheffer, G.L.3    Scheper, R.J.4    Vaneijk, M.J.T.5    Juijn, J.A.6
  • 124
    • 0032893268 scopus 로고    scopus 로고
    • Expression of human MRP6, a homologue of the multidrug resistance protein gene MRP1, in tissues and cancer cells
    • Kool, M., van der Linden, M., de Haas, M., Baas, F. (1999). Expression of human MRP6, a homologue of the multidrug resistance protein gene MRP1, in tissues and cancer cells. Cancer Res 59:175-182.
    • (1999) Cancer Res , vol.59 , pp. 175-182
    • Kool, M.1    Van Der Linden, M.2    De Haas, M.3    Baas, F.4
  • 125
    • 0037203464 scopus 로고    scopus 로고
    • Bioactive compounds in foods: Their role in the prevention of cardiovascular disease and cancer
    • Kris-Etherton, P. M., Hecker, K. D., Bonanome, A., Coval, S. M., Binkoski, A. E., Hilpert, K. F., et al. (2002). Bioactive compounds in foods: their role in the prevention of cardiovascular disease and cancer. Am J Med 113:71-88.
    • (2002) Am J Med , vol.113 , pp. 71-88
    • Kris-Etherton, P.M.1    Hecker, K.D.2    Bonanome, A.3    Coval, S.M.4    Binkoski, A.E.5    Hilpert, K.F.6
  • 127
    • 33644503533 scopus 로고    scopus 로고
    • Distribution and functional activity of P-glycoprotein and multidrug-resistance-associated proteins in human brain microvascular endothelial cells in hippocampal sclerosis
    • Kubota, H., Ishihara, H., Langmann, T., Schmitz, G., Stieger, B., Wieser, H. G., et al. (2006). Distribution and functional activity of P-glycoprotein and multidrug-resistance-associated proteins in human brain microvascular endothelial cells in hippocampal sclerosis. Epilepsy Res 68:213-228.
    • (2006) Epilepsy Res , vol.68 , pp. 213-228
    • Kubota, H.1    Ishihara, H.2    Langmann, T.3    Schmitz, G.4    Stieger, B.5    Wieser, H.G.6
  • 129
    • 34248573808 scopus 로고    scopus 로고
    • Curcumin potentiates antitumor activity of gemcitabine in an orthotopic model of pancreatic cancer through suppression of proliferation, angiogenesis, and inhibition of nuclear factor-kappaB-regulated gene products
    • Kunnumakkara, A. B., Guha, S., Krishnan, S., Diagaradjane, P., Gelovani, J., Aggarwal, B. B. (2007). Curcumin potentiates antitumor activity of gemcitabine in an orthotopic model of pancreatic cancer through suppression of proliferation, angiogenesis, and inhibition of nuclear factor-kappaB-regulated gene products. Cancer Res 67:3853-3861.
    • (2007) Cancer Res , vol.67 , pp. 3853-3861
    • Kunnumakkara, A.B.1    Guha, S.2    Krishnan, S.3    Diagaradjane, P.4    Gelovani, J.5    Aggarwal, B.B.6
  • 130
    • 61649094969 scopus 로고    scopus 로고
    • Curcumin as a possible lead compound against hormone-independent, multidrug-resistant breast cancer
    • Labbozzetta, M., Notarbartolo, M., Poma, P., Maurici, A., Inguglia, L., Marchetti, P., et al. (2009). Curcumin as a possible lead compound against hormone-independent, multidrug-resistant breast cancer. Ann N Y Acad Sci 1155:278-283.
    • (2009) Ann N y Acad Sci , vol.1155 , pp. 278-283
    • Labbozzetta, M.1    Notarbartolo, M.2    Poma, P.3    Maurici, A.4    Inguglia, L.5    Marchetti, P.6
  • 131
    • 34247149458 scopus 로고    scopus 로고
    • Modulation of GSH levels in ABCC1 expressing tumor cells triggers apoptosis through oxidative stress
    • Laberge, R. M., Karwatsky, J., Lincoln, M. C., Leimanis, M. L., Georges, E. (2007). Modulation of GSH levels in ABCC1 expressing tumor cells triggers apoptosis through oxidative stress. Biochem Pharmacol 73:1727-1737.
    • (2007) Biochem Pharmacol , vol.73 , pp. 1727-1737
    • Laberge, R.M.1    Karwatsky, J.2    Lincoln, M.C.3    Leimanis, M.L.4    Georges, E.5
  • 132
    • 0035015140 scopus 로고    scopus 로고
    • Inhibitory effect of steroidal alkaloids on drug transport and multidrug resistance in human cancer cells
    • Lavie, Y., Harel-Orbital, T., Gaffield, W., Liscovitch, M. (2001). Inhibitory effect of steroidal alkaloids on drug transport and multidrug resistance in human cancer cells. Anticancer Res 21:1189-1194.
    • (2001) Anticancer Res , vol.21 , pp. 1189-1194
    • Lavie, Y.1    Harel-Orbital, T.2    Gaffield, W.3    Liscovitch, M.4
  • 133
    • 11844267237 scopus 로고    scopus 로고
    • Investigation of efflux transport of dehydroepiandroster- one sulfate and mitoxantrone at the mouse blood-brain barrier: A minor role of breast cancer resistance protein
    • Lee, Y. J., Kusuhara, H., Jonker, J. W., Schinkel, A. H, Sugiyama, Y. (2005). Investigation of efflux transport of dehydroepiandroster- one sulfate and mitoxantrone at the mouse blood-brain barrier: a minor role of breast cancer resistance protein. J Pharmacol Exp Ther 312:44-52.
    • (2005) J Pharmacol Exp Ther , vol.312 , pp. 44-52
    • Lee, Y.J.1    Kusuhara, H.2    Jonker, J.W.3    Schinkel, A.H.4    Sugiyama, Y.5
  • 134
    • 0013016426 scopus 로고    scopus 로고
    • Bioflavonoid stimulation of glutathione transport by the 190-kDa multidrug resistance protein 1 (MRP1)
    • Leslie, E. M., Deeley, R. G., Cole, S. P. (2003). Bioflavonoid stimulation of glutathione transport by the 190-kDa multidrug resistance protein 1 (MRP1). Drug Metab Dispos 31:11-15.
    • (2003) Drug Metab Dispos , vol.31 , pp. 11-15
    • Leslie, E.M.1    Deeley, R.G.2    Cole, S.P.3
  • 135
    • 17544368685 scopus 로고    scopus 로고
    • Multidrug resistance proteins: Role of P-glycoprotein, MRP1, MRP2, and BCRP (ABCG2) in tissue defense
    • Leslie, E. M., Deeley, R. G., Cole, S. P. (2005). Multidrug resistance proteins: role of P-glycoprotein, MRP1, MRP2, and BCRP (ABCG2) in tissue defense. Toxicol Appl Pharmacol 204:216-237.
    • (2005) Toxicol Appl Pharmacol , vol.204 , pp. 216-237
    • Leslie, E.M.1    Deeley, R.G.2    Cole, S.P.3
  • 136
    • 33846233855 scopus 로고    scopus 로고
    • Dibenzocyclooctadiene lignans: A class of novel inhibitors of multidrug-resistance-asso- ciated protein 1
    • Li, L., Pan, Q., Sun, M., Lu, Q., Hu, X. (2007a). Dibenzocyclooctadiene lignans: a class of novel inhibitors of multidrug-resistance-asso- ciated protein 1. Life Sci 80:741-748.
    • (2007) Life Sci , vol.80 , pp. 741-748
    • Li, L.1    Pan, Q.2    Sun, M.3    Lu, Q.4    Hu, X.5
  • 137
    • 34250156691 scopus 로고    scopus 로고
    • Transport and metabolism of MitoQ10, a mitochondria-targeted antioxidant, in Caco-2 cell monolayers
    • Li, Y., Fawcett, J. P., Zhang, H., Tucker, I. G. (2007b). Transport and metabolism of MitoQ10, a mitochondria-targeted antioxidant, in Caco-2 cell monolayers. J Pharm Pharmacol 59:503-511.
    • (2007) J Pharm Pharmacol , vol.59 , pp. 503-511
    • Li, Y.1    Fawcett, J.P.2    Zhang, H.3    Tucker, I.G.4
  • 138
    • 28844481986 scopus 로고    scopus 로고
    • Effects of citrus fruit juices on cytotoxicity and drug transport pathways of Caco-2 cell monolayers
    • Lim, S. L., Lim, L. Y. (2006). Effects of citrus fruit juices on cytotoxicity and drug transport pathways of Caco-2 cell monolayers. Int J Pharm 307:42-50.
    • (2006) Int J Pharm , vol.307 , pp. 42-50
    • Lim, S.L.1    Lim, L.Y.2
  • 139
    • 34447506459 scopus 로고    scopus 로고
    • Modulation of function of three ABC drug transporters, P-glycoprotein (ABCB1), mitoxantrone resistance protein (ABCG2), and multidrug resistance protein 1 (ABCC1), by tet- rahydrocurcumin, a major metabolite of curcumin
    • Limtrakul, P., Chearwae, W., Shukla, S., Phisalphong, C., Ambudkar, S. V. (2007). Modulation of function of three ABC drug transporters, P-glycoprotein (ABCB1), mitoxantrone resistance protein (ABCG2), and multidrug resistance protein 1 (ABCC1), by tet- rahydrocurcumin, a major metabolite of curcumin. Mol Cell Biochem 296:85-95.
    • (2007) Mol Cell Biochem , vol.296 , pp. 85-95
    • Limtrakul, P.1    Chearwae, W.2    Shukla, S.3    Phisalphong, C.4    Ambudkar, S.V.5
  • 140
    • 38149073214 scopus 로고    scopus 로고
    • A review on the impact of P-glycoprotein on the penetration of drugs into the brain Focus on psychotropic drugs
    • Linnet, K., Ejsing, T. B. (2008). A review on the impact of P-glycoprotein on the penetration of drugs into the brain. Focus on psychotropic drugs. Eur Neuropsychopharmacol 18:157-169.
    • (2008) Eur Neuropsychopharmacol , vol.18 , pp. 157-169
    • Linnet, K.1    Ejsing, T.B.2
  • 141
    • 0034947674 scopus 로고    scopus 로고
    • From MDR to MXR: New understanding of multidrug resistance systems, their properties, and clinical significance
    • Litman, T., Druley, T. E., Stein, W. D., Bates, S. E. (2001). From MDR to MXR: new understanding of multidrug resistance systems, their properties, and clinical significance. Cell Mol Life Sci 58:931-959.
    • (2001) Cell Mol Life Sci , vol.58 , pp. 931-959
    • Litman, T.1    Druley, T.E.2    Stein, W.D.3    Bates, S.E.4
  • 142
    • 13444252334 scopus 로고    scopus 로고
    • Low-dose dietary phytoestrogen abrogates tamoxifen-associated mammary tumor prevention
    • Liu, B., Edgerton, S., Yang, X., Kim, A., Ordonez-Ercan, D., Mason, T., et al. (2005). Low-dose dietary phytoestrogen abrogates tamoxifen-associated mammary tumor prevention. Cancer Res 65:879-886.
    • (2005) Cancer Res , vol.65 , pp. 879-886
    • Liu, B.1    Edgerton, S.2    Yang, X.3    Kim, A.4    Ordonez-Ercan, D.5    Mason, T.6
  • 143
    • 71049183577 scopus 로고    scopus 로고
    • Absorption and disposition of ginsenosides after oral administration of Panax notoginseng extract to rats
    • Liu, H., Yang, J., Du, F., Gao, X., Ma, X., Huang, Y., et al. (2009). Absorption and disposition of ginsenosides after oral administration of Panax notoginseng extract to rats. Drug Metab Dispos 37:2290-2298.
    • (2009) Drug Metab Dispos , vol.37 , pp. 2290-2298
    • Liu, H.1    Yang, J.2    Du, F.3    Gao, X.4    Ma, X.5    Huang, Y.6
  • 144
    • 48649092518 scopus 로고    scopus 로고
    • Lobeline, a piperidine alkaloid from Lobelia, can reverse P-gp-dependent multidrug resistance in tumor cells
    • Ma, Y., Wink, M. (2008). Lobeline, a piperidine alkaloid from Lobelia, can reverse P-gp-dependent multidrug resistance in tumor cells. Phytomedicine 15:754-758.
    • (2008) Phytomedicine , vol.15 , pp. 754-758
    • Ma, Y.1    Wink, M.2
  • 145
    • 22344433760 scopus 로고    scopus 로고
    • Induction of the multidrug-resistance-associated protein family of transporters by chemical activators of receptor-mediated pathways in mouse liver
    • Maher, J. M., Cheng, X., Slitt, A. L., Dieter, M. Z., Klaassen, C. D. (2005). Induction of the multidrug-resistance-associated protein family of transporters by chemical activators of receptor-mediated pathways in mouse liver. Drug Metab Dispos 33:956-962.
    • (2005) Drug Metab Dispos , vol.33 , pp. 956-962
    • Maher, J.M.1    Cheng, X.2    Slitt, A.L.3    Dieter, M.Z.4    Klaassen, C.D.5
  • 146
    • 0035865162 scopus 로고    scopus 로고
    • Coadministration of cyclosporine strongly enhances the oral bioavailability of docetaxel
    • Malingre, M., Richel, D. (2001). Coadministration of cyclosporine strongly enhances the oral bioavailability of docetaxel. J Clin Oncol 19:1160-1166.
    • (2001) J Clin Oncol , vol.19 , pp. 1160-1166
    • Malingre, M.1    Richel, D.2
  • 147
    • 13844281685 scopus 로고    scopus 로고
    • Bioavailability and bioefficacy of polyphenols in humans. I. Review of 97 bioavailability studies
    • Manach, C., Williamson, G., Morand, C., Scalbert, A., Remesy, C. (2005). Bioavailability and bioefficacy of polyphenols in humans. I. Review of 97 bioavailability studies. Am J Clin Nutr 81:230S-242S.
    • (2005) Am J Clin Nutr , vol.81
    • Manach, C.1    Williamson, G.2    Morand, C.3    Scalbert, A.4    Remesy, C.5
  • 148
    • 53349099403 scopus 로고    scopus 로고
    • Effect of the ATP-binding cassette drug transporters, ABCB1, ABCG2, and ABCC2, on erlotinib hydrochloride (Tarceva) disposition in in vitro and in vivo phar- macokinetic studies employing Bcrp1-/-/Mdr1a/1b-/- (triple- knockout) and wild-type mice
    • Marchetti, S., de Vries, N. A., Buckle, T., Bolijn, M. J., van Eijndhoven, M. A., Beijnen, J. H., et al. (2008). Effect of the ATP-binding cassette drug transporters, ABCB1, ABCG2, and ABCC2, on erlotinib hydrochloride (Tarceva) disposition in in vitro and in vivo phar- macokinetic studies employing Bcrp1-/-/Mdr1a/1b-/- (triple- knockout) and wild-type mice. Mol Cancer Ther 7:2280-2287.
    • (2008) Mol Cancer Ther , vol.7 , pp. 2280-2287
    • Marchetti, S.1    De Vries, N.A.2    Buckle, T.3    Bolijn, M.J.4    Van Eijndhoven, M.A.5    Beijnen, J.H.6
  • 149
    • 33846419807 scopus 로고    scopus 로고
    • How can we best use structural information on P-glycoprotein to design inhibitors?
    • McDevitt, C. A., Callaghan, R. (2007). How can we best use structural information on P-glycoprotein to design inhibitors? Pharmacol Ther 113:429-441.
    • (2007) Pharmacol Ther , vol.113 , pp. 429-441
    • McDevitt, C.A.1    Callaghan, R.2
  • 150
    • 70449635126 scopus 로고    scopus 로고
    • Role of basolateral efflux transporter MRP4 in the intestinal absorption of the antiviral drug adefovir, dipivoxil
    • Ming, X., Thakker, D. R. (2009). Role of basolateral efflux transporter MRP4 in the intestinal absorption of the antiviral drug adefovir, dipivoxil. Biochem Pharmacol 79:455-462.
    • (2009) Biochem Pharmacol , vol.79 , pp. 455-462
    • Ming, X.1    Thakker, D.R.2
  • 151
    • 0034600237 scopus 로고    scopus 로고
    • Effect of bioflavonoids on vincristine transport across blood- brain barrier
    • Mitsunaga, Y., Takanaga, H., Matsuo, H., Naito, M., Tsuruo, T. (2000). Effect of bioflavonoids on vincristine transport across blood- brain barrier. Eur J Pharmacol 395:193-201.
    • (2000) Eur J Pharmacol , vol.395 , pp. 193-201
    • Mitsunaga, Y.1    Takanaga, H.2    Matsuo, H.3    Naito, M.4    Tsuruo, T.5
  • 152
    • 0042468096 scopus 로고    scopus 로고
    • Impact of drug-transporter studies on drug discovery and development
    • Mizuno, N., Niwa, T., Yotsumoto, Y., Sugiyama, Y. (2003). Impact of drug-transporter studies on drug discovery and development. Pharmacol Rev 55:425-461.
    • (2003) Pharmacol Rev , vol.55 , pp. 425-461
    • Mizuno, N.1    Niwa, T.2    Yotsumoto, Y.3    Sugiyama, Y.4
  • 153
    • 4143107239 scopus 로고    scopus 로고
    • Impaired renal excretion of 6-hydroxy-5,7-dime- thyl-2-methylamino-4-(3- pyridylmethyl) benzothiazole (E3040) sulfate in breast cancer resistance protein (BCRP1/ABCG2) knockout mice
    • Mizuno, N., Suzuki, M., Kusuhara, H., Suzuki, H., Takeuchi, K., Niwa, T., et al. (2004). Impaired renal excretion of 6-hydroxy-5,7-dime- thyl-2-methylamino-4-(3-pyridylmethyl) benzothiazole (E3040) sulfate in breast cancer resistance protein (BCRP1/ABCG2) knockout mice. Drug Metab Dispos 32:898-901.
    • (2004) Drug Metab Dispos , vol.32 , pp. 898-901
    • Mizuno, N.1    Suzuki, M.2    Kusuhara, H.3    Suzuki, H.4    Takeuchi, K.5    Niwa, T.6
  • 154
    • 1842841638 scopus 로고    scopus 로고
    • Modulation of multidrug resistance and apop- tosis of cancer cells by selected carotenoids
    • Molnar, J., Gyemant, N., Mucsi, I., Molnar, A., Szabo, M., Kortvelyesi, T., et al. (2004). Modulation of multidrug resistance and apop- tosis of cancer cells by selected carotenoids. In Vivo 18:237-244.
    • (2004) In Vivo , vol.18 , pp. 237-244
    • Molnar, J.1    Gyemant, N.2    Mucsi, I.3    Molnar, A.4    Szabo, M.5    Kortvelyesi, T.6
  • 156
    • 0034053334 scopus 로고    scopus 로고
    • Membrane-associated antitumor effects of croc- ine-, ginsenoside-, and cannabinoid derivates
    • Molnar, J., Szabo, D., Pusztai, R., Mucsi, I., Berek, L., Ocsovszki, I., et al. (2000). Membrane-associated antitumor effects of croc- ine-, ginsenoside-, and cannabinoid derivates. Anticancer Res 20:861-867.
    • (2000) Anticancer Res , vol.20 , pp. 861-867
    • Molnar, J.1    Szabo, D.2    Pusztai, R.3    Mucsi, I.4    Berek, L.5    Ocsovszki, I.6
  • 157
    • 37549031270 scopus 로고    scopus 로고
    • Pharmacokinetics and bioavailability of the bioflavonoid biochanin A: Effects of quercetin and EGCG on biochanin a disposition in rats
    • Moon, Y. J., Morris, M. E. (2007). Pharmacokinetics and bioavailability of the bioflavonoid biochanin A: effects of quercetin and EGCG on biochanin a disposition in rats. Mol Pharm 4:865-872.
    • (2007) Mol Pharm , vol.4 , pp. 865-872
    • Moon, Y.J.1    Morris, M.E.2
  • 158
    • 33644914487 scopus 로고    scopus 로고
    • Flavonoid-drug interactions: Effects of flavonoids on ABC transporters
    • Morris, M. E., Zhang, S. Z. (2006). Flavonoid-drug interactions: effects of flavonoids on ABC transporters. Life Sci 78:2116-2130.
    • (2006) Life Sci , vol.78 , pp. 2116-2130
    • Morris, M.E.1    Zhang, S.Z.2
  • 159
    • 84934436443 scopus 로고    scopus 로고
    • Highly active anticancer curcumin analogues
    • Mosley, C. A., Liotta, D. C., Snyder, J. P. (2007). Highly active anticancer curcumin analogues. Adv Exp Med Biol 595:77-103.
    • (2007) Adv Exp Med Biol , vol.595 , pp. 77-103
    • Mosley, C.A.1    Liotta, D.C.2    Snyder, J.P.3
  • 160
    • 11844301652 scopus 로고    scopus 로고
    • Effects of dietary chemopreventive phytochemicals on P-glycoprotein function
    • Nabekura, T., Kamiyama, S., Kitagawa, S. (2005). Effects of dietary chemopreventive phytochemicals on P-glycoprotein function. Biochem Biophys Res Commun 327:866-870.
    • (2005) Biochem Biophys Res Commun , vol.327 , pp. 866-870
    • Nabekura, T.1    Kamiyama, S.2    Kitagawa, S.3
  • 161
    • 49749143424 scopus 로고    scopus 로고
    • Inhibition of P-glycoprotein and multidrug resistance protein 1 by dietary phy- tochemicals
    • Nabekura, T., Yamaki, T., Ueno, K., Kitagawa, S. (2008). Inhibition of P-glycoprotein and multidrug resistance protein 1 by dietary phy- tochemicals. Cancer Chemother Pharmacol 62:867-873.
    • (2008) Cancer Chemother Pharmacol , vol.62 , pp. 867-873
    • Nabekura, T.1    Yamaki, T.2    Ueno, K.3    Kitagawa, S.4
  • 163
    • 0034068093 scopus 로고    scopus 로고
    • Phase i study of CBT-1 and Taxol in patients with Taxol-resistant cancers
    • Oldham, R. K., Reid, W. K., Barnett, D. (2000). Phase I study of CBT-1 and Taxol in patients with Taxol-resistant cancers. Cancer Biother Radiopharm 15:153-159.
    • (2000) Cancer Biother Radiopharm , vol.15 , pp. 153-159
    • Oldham, R.K.1    Reid, W.K.2    Barnett, D.3
  • 165
    • 2442638937 scopus 로고    scopus 로고
    • High-affinity interaction of tyrosine kinase inhibitors with the ABCG2 multidrug transporter
    • Ozvegy-Laczka, C., Hegedus, T., Varady, G., Ujhelly, O., Schuetz, J. D., Varadi, A., et al. (2004). High-affinity interaction of tyrosine kinase inhibitors with the ABCG2 multidrug transporter. Mol Pharmacol 65:1485-1495.
    • (2004) Mol Pharmacol , vol.65 , pp. 1485-1495
    • Ozvegy-Laczka, C.1    Hegedus, T.2    Varady, G.3    Ujhelly, O.4    Schuetz, J.D.5    Varadi, A.6
  • 166
    • 2342533129 scopus 로고    scopus 로고
    • Structure-function relationships of multidrug resistance P-glycoprotein
    • Pajeva, I. K., Globisch, C., Wiese, M. (2004). Structure-function relationships of multidrug resistance P-glycoprotein. J Med Chem 47:2523-2533.
    • (2004) J Med Chem , vol.47 , pp. 2523-2533
    • Pajeva, I.K.1    Globisch, C.2    Wiese, M.3
  • 167
    • 33645976829 scopus 로고    scopus 로고
    • Dibenzocyclooctadiene lingnans: A class of novel inhibitors of P-glycoprotein
    • Pan, Q., Lu, Q., Zhang, K., Hu, X. (2006). Dibenzocyclooctadiene lingnans: a class of novel inhibitors of P-glycoprotein. Cancer Chemother Pharmacol 58:99-106.
    • (2006) Cancer Chemother Pharmacol , vol.58 , pp. 99-106
    • Pan, Q.1    Lu, Q.2    Zhang, K.3    Hu, X.4
  • 168
    • 0032528254 scopus 로고    scopus 로고
    • Multidrug-resistance transporter P-glycoprotein has distinct but interactive binding sites for cytotoxic drugs and reversing agents
    • Pascaud, C., Garrigos, M. (1998). Multidrug-resistance transporter P-glycoprotein has distinct but interactive binding sites for cytotoxic drugs and reversing agents. Biochemical J 333: 3351-3358.
    • (1998) Biochemical J , vol.333 , pp. 3351-3358
    • Pascaud, C.1    Garrigos, M.2
  • 169
    • 58849112270 scopus 로고    scopus 로고
    • Inhibition of P-glycoprotein-mediated paclitaxel resistance by reversibly linked quinine homodimers
    • Pires, M. M., Emmert, D., Hrycyna, C. A., Chmielewski, J. (2009). Inhibition of P-glycoprotein-mediated paclitaxel resistance by reversibly linked quinine homodimers. Mol Pharmacol 75:92-100.
    • (2009) Mol Pharmacol , vol.75 , pp. 92-100
    • Pires, M.M.1    Emmert, D.2    Hrycyna, C.A.3    Chmielewski, J.4
  • 170
    • 76749169561 scopus 로고    scopus 로고
    • Increased ubiquitination of multidrug resistance 1 by ginseno- side Rd
    • Pokharel, Y. R., Kim, N. D., Han, H. K., Oh, W. K., Kang, K. W. (2010). Increased ubiquitination of multidrug resistance 1 by ginseno- side Rd. Nutr Cancer 62:252-259.
    • (2010) Nutr Cancer , vol.62 , pp. 252-259
    • Pokharel, Y.R.1    Kim, N.D.2    Han, H.K.3    Oh, W.K.4
  • 171
    • 20044383925 scopus 로고    scopus 로고
    • The multidrug resistance protein 5 (ABCC5) confers resistance to 5-fluorouracil and transports its monophosphorylated metabolites
    • Pratt, S., Shepard, R. L., Kandasamy, R. A., Johnston, P. A., Perry, W., 3rd, and Dantzig, A. H. (2005). The multidrug resistance protein 5 (ABCC5) confers resistance to 5-fluorouracil and transports its monophosphorylated metabolites. Mol Cancer Ther 4:855-863.
    • (2005) Mol Cancer Ther , vol.4 , pp. 855-863
    • Pratt, S.1    Shepard, R.L.2    Kandasamy, R.A.3    Johnston, P.A.4    Perry III, W.5    Dantzig, A.H.6
  • 172
    • 34548134497 scopus 로고    scopus 로고
    • Increased uptake of quinine into the brain by inhibition of P-glycoprotein
    • Pussard, E., Merzouk, M., Barennes, H. (2007). Increased uptake of quinine into the brain by inhibition of P-glycoprotein. Eur J Pharm Sci 32:123-127.
    • (2007) Eur J Pharm Sci , vol.32 , pp. 123-127
    • Pussard, E.1    Merzouk, M.2    Barennes, H.3
  • 173
  • 174
    • 0033966957 scopus 로고    scopus 로고
    • Fumitremorgin C reverses multidrug resistance in cells transfected with the breast cancer resistance protein
    • Rabindran, S. K., Ross, D., Doyle, A., Yang, W., Greenberger, L. M. (2000). Fumitremorgin C reverses multidrug resistance in cells transfected with the breast cancer resistance protein. Cancer Res 60:47-50. (Pubitemid 30058728)
    • (2000) Cancer Research , vol.60 , Issue.1 , pp. 47-50
    • Rabindran, S.K.1    Ross, D.D.2    Doyle, L.A.3    Yang, W.4    Greenberger, L.M.5
  • 176
    • 0043132421 scopus 로고    scopus 로고
    • The human multidrug resistance protein, MRP4, functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs
    • Reid, G., Wielinga, P., Zelcer, N., van der Heijden, I., Kuil, A., de Haas, M., et al. (2003) The human multidrug resistance protein, MRP4, functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs. Proc Natl Acad Sci U S A 100:9244-9249.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 9244-9249
    • Reid, G.1    Wielinga, P.2    Zelcer, N.3    Van Der Heijden, I.4    Kuil, A.5    De Haas, M.6
  • 177
    • 0042766881 scopus 로고    scopus 로고
    • Cotransport of reduced glutathione with bile salts by MRP4 (ABCC4) localized to the basolateral hepatocyte membrane
    • Rius, M., Nies, A. T., Hummel-Eisenbeiss, J., Jedlitschky, G., Keppler, D. (2003). Cotransport of reduced glutathione with bile salts by MRP4 (ABCC4) localized to the basolateral hepatocyte membrane. Hepatology 38:374-384.
    • (2003) Hepatology , vol.38 , pp. 374-384
    • Rius, M.1    Nies, A.T.2    Hummel-Eisenbeiss, J.3    Jedlitschky, G.4    Keppler, D.5
  • 178
    • 39749135394 scopus 로고    scopus 로고
    • Inhibition of P-glycoprotein (ABCB1)- and multidrug-resistance-associated protein 1 (ABCC1)-mediated transport by the orally administered inhibitor, CBT-1((R))
    • Robey, R. W., Shukla, S., Finley, E. M., Oldham, R. K., Barnett, D., Ambudkar, S. V., et al. (2008). Inhibition of P-glycoprotein (ABCB1)- and multidrug-resistance-associated protein 1 (ABCC1)-mediated transport by the orally administered inhibitor, CBT-1((R)). Biochem Pharmacol 75:1302-1312.
    • (2008) Biochem Pharmacol , vol.75 , pp. 1302-1312
    • Robey, R.W.1    Shukla, S.2    Finley, E.M.3    Oldham, R.K.4    Barnett, D.5    Ambudkar, S.V.6
  • 179
    • 0038121803 scopus 로고    scopus 로고
    • ATP-binding cassette transporter gene expression in rat liver progenitor cells
    • Ros, J. E., Roskams, T. A., Geuken, M., Havinga, R., Splinter, P. L., Petersen, B. E., et al. (2003). ATP-binding cassette transporter gene expression in rat liver progenitor cells. Gut 52:1060-1067.
    • (2003) Gut , vol.52 , pp. 1060-1067
    • Ros, J.E.1    Roskams, T.A.2    Geuken, M.3    Havinga, R.4    Splinter, P.L.5    Petersen, B.E.6
  • 180
    • 0032412212 scopus 로고    scopus 로고
    • Protein kinases and multidrug resistance
    • Rumsby, M., Drew, L., Warr, J. (1998). Protein kinases and multidrug resistance. Cytotechnology 27:203-224.
    • (1998) Cytotechnology , vol.27 , pp. 203-224
    • Rumsby, M.1    Drew, L.2    Warr, J.3
  • 181
    • 34447283477 scopus 로고    scopus 로고
    • Ins and outs of dietary phytochemicals in cancer chemoprevention
    • Russo, G. L. (2007). Ins and outs of dietary phytochemicals in cancer chemoprevention. Biochem Pharmacol 74:533-544.
    • (2007) Biochem Pharmacol , vol.74 , pp. 533-544
    • Russo, G.L.1
  • 182
    • 0033937909 scopus 로고    scopus 로고
    • Sulphation of resveratrol, a natural product present in grapes and wine, in the human liver and duodenum
    • Santi, C. D., Pietrabissa, A., Spisni, R., Mosca, F., Pacifici, G. M. (2000). Sulphation of resveratrol, a natural product present in grapes and wine, in the human liver and duodenum. Xenobiotica 30:609-617.
    • (2000) Xenobiotica , vol.30 , pp. 609-617
    • Santi, C.D.1    Pietrabissa, A.2    Spisni, R.3    Mosca, F.4    Pacifici, G.M.5
  • 183
    • 33749488939 scopus 로고    scopus 로고
    • Human multidrug resistance ABCB and ABCG transporters: Participation in a chemoimmunity defense system
    • Sarkadi, B., Homolya, L., Szakacs, G., Varadi, A. (2006). Human multidrug resistance ABCB and ABCG transporters: participation in a chemoimmunity defense system. Physiol Rev 86:1179-1236.
    • (2006) Physiol Rev , vol.86 , pp. 1179-1236
    • Sarkadi, B.1    Homolya, L.2    Szakacs, G.3    Varadi, A.4
  • 184
    • 70350225860 scopus 로고    scopus 로고
    • Harnessing the fruits of nature for the development of multitargeted cancer therapeutics
    • Sarkar, F. H., Li, Y. (2009). Harnessing the fruits of nature for the development of multitargeted cancer therapeutics. Cancer Treat Rev 35:597-607.
    • (2009) Cancer Treat Rev , vol.35 , pp. 597-607
    • Sarkar, F.H.1    Li, Y.2
  • 185
    • 34548406410 scopus 로고    scopus 로고
    • Targeting multiple signal pathways by chemopreventive agents for cancer prevention and therapy
    • Sarkar, F. H., Li, Y. W. (2007). Targeting multiple signal pathways by chemopreventive agents for cancer prevention and therapy. Acta Pharmacol Sin 28:1305-1315.
    • (2007) Acta Pharmacol Sin , vol.28 , pp. 1305-1315
    • Sarkar, F.H.1    Li, Y.W.2
  • 186
    • 47849122700 scopus 로고    scopus 로고
    • Activation of pregnane X receptor and induction of MDR1 by dietary phytochemicals
    • Satsu, H., Hiura, Y., Mochizuki, K., Hamada, M., Shimizu, M. (2008). Activation of pregnane X receptor and induction of MDR1 by dietary phytochemicals. J Agric Food Chem 56:5366-5373.
    • (2008) J Agric Food Chem , vol.56 , pp. 5366-5373
    • Satsu, H.1    Hiura, Y.2    Mochizuki, K.3    Hamada, M.4    Shimizu, M.5
  • 187
    • 0027981909 scopus 로고
    • Quercetin potentiates the effect of adriamycin in a multidrug-resistant MCF-7 human breast-cancer cell line: P-glycoprotein as a possible target
    • Scambia, G., Ranelletti, F. O., Panici, P. B., De Vincenzo, R., Bonanno, G., Ferrandina, G., et al. (1994). Quercetin potentiates the effect of adriamycin in a multidrug-resistant MCF-7 human breast-cancer cell line: P-glycoprotein as a possible target. Cancer Chemother Pharmacol 34:459-464.
    • (1994) Cancer Chemother Pharmacol , vol.34 , pp. 459-464
    • Scambia, G.1    Ranelletti, F.O.2    Panici, P.B.3    De Vincenzo, R.4    Bonanno, G.5    Ferrandina, G.6
  • 188
    • 0034111043 scopus 로고    scopus 로고
    • P-glycoprotein inhibitor erythromycin increases oral bioavailability of talinolol in humans
    • Schwarz, U., Gramatte, T., Krappweis, J., Oertel, R., Kirch, W. (2000). P-glycoprotein inhibitor erythromycin increases oral bioavailability of talinolol in humans. Int J Clin Pharmacol Ther 38:161-167.
    • (2000) Int J Clin Pharmacol Ther , vol.38 , pp. 161-167
    • Schwarz, U.1    Gramatte, T.2    Krappweis, J.3    Oertel, R.4    Kirch, W.5
  • 189
    • 21744461919 scopus 로고    scopus 로고
    • Breast cancer resistance protein (Bcrp1/Abcg2) limits net intestinal uptake of quercetin in rats by facilitating apical efflux of glucuronides
    • Sesink, A. L. A., Arts, I. C. W., de Boer, V. C. J., Breedveld, P., Schellens, J. H. M., Hollman, P. C. H., et al. (2005). Breast cancer resistance protein (Bcrp1/Abcg2) limits net intestinal uptake of quercetin in rats by facilitating apical efflux of glucuronides. Mol Pharmacol 67:1999-2006.
    • (2005) Mol Pharmacol , vol.67 , pp. 1999-2006
    • Sesink, A.L.A.1    Arts, I.C.W.2    De Boer, V.C.J.3    Breedveld, P.4    Schellens, J.H.M.5    Hollman, P.C.H.6
  • 190
    • 67349107075 scopus 로고    scopus 로고
    • Nanoparticle encapsulation improves oral bioavailability of curcumin by at least 9-fold when compared to curcumin administered with piperine as absorption enhancer
    • Shaikh, J., Ankola, D. D., Beniwal, V., Singh, D., Kumar, M. N. (2009). Nanoparticle encapsulation improves oral bioavailability of curcumin by at least 9-fold when compared to curcumin administered with piperine as absorption enhancer. Eur J Pharm Sci 37:223-230.
    • (2009) Eur J Pharm Sci , vol.37 , pp. 223-230
    • Shaikh, J.1    Ankola, D.D.2    Beniwal, V.3    Singh, D.4    Kumar, M.N.5
  • 191
    • 0030782511 scopus 로고    scopus 로고
    • Positively cooperative sites for drug transport by P-glycoprotein with distinct drug specifities
    • Shapiro, A. B., Ling, V. (1997). Positively cooperative sites for drug transport by P-glycoprotein with distinct drug specifities. Eur J Biochem 250:130-137.
    • (1997) Eur J Biochem , vol.250 , pp. 130-137
    • Shapiro, A.B.1    Ling, V.2
  • 192
    • 65349175650 scopus 로고    scopus 로고
    • Newly synthesized curcumin analog has improved potential to prevent colorectal carcinogenesis in vivo
    • Shibata, H., Yamakoshi, H., Sato, A., Ohori, H., Kakudo, Y., Kudo, C., et al. (2009). Newly synthesized curcumin analog has improved potential to prevent colorectal carcinogenesis in vivo. Cancer Sci 100:956-960.
    • (2009) Cancer Sci , vol.100 , pp. 956-960
    • Shibata, H.1    Yamakoshi, H.2    Sato, A.3    Ohori, H.4    Kakudo, Y.5    Kudo, C.6
  • 193
    • 0026756347 scopus 로고
    • P-glycoprotein. ATP hydrolysis by the N-terminal nucleotide- binding domain
    • Shimabuku, A. M., Nishimoto, T., Ueda, K., Komano, T. (1992). P-glycoprotein. ATP hydrolysis by the N-terminal nucleotide- binding domain. J Biol Chem 267:4308-4311.
    • (1992) J Biol Chem , vol.267 , pp. 4308-4311
    • Shimabuku, A.M.1    Nishimoto, T.2    Ueda, K.3    Komano, T.4
  • 194
    • 60049089374 scopus 로고    scopus 로고
    • Concentration-dependent effect of naringin on intestinal absorption of p1-adrenoceptor antagonist talinolol mediated by P-glycoprotein and organic anion transporting polypeptide (Oatp)
    • Shirasaka, Y., Li, Y., Shibue, Y., Kuraoka, E., Spahn-Langguth, H., Kato, Y., et al. (2009). Concentration-dependent effect of naringin on intestinal absorption of p1-adrenoceptor antagonist talinolol mediated by P-glycoprotein and organic anion transporting polypeptide (Oatp). Pharm Res 26:560-567.
    • (2009) Pharm Res , vol.26 , pp. 560-567
    • Shirasaka, Y.1    Li, Y.2    Shibue, Y.3    Kuraoka, E.4    Spahn-Langguth, H.5    Kato, Y.6
  • 195
    • 33644847684 scopus 로고    scopus 로고
    • Transporters as a determinant of drug clearance and tissue distribution
    • Shitara, Y., Horie, T., Sugiyama, Y. (2006). Transporters as a determinant of drug clearance and tissue distribution. Eur J Pharm Sci 27:425-446.
    • (2006) Eur J Pharm Sci , vol.27 , pp. 425-446
    • Shitara, Y.1    Horie, T.2    Sugiyama, Y.3
  • 196
    • 0031860081 scopus 로고    scopus 로고
    • Influence of piperine on the pharmacokinetics of curcu- min in animals and human volunteers
    • Shoba, G., Joy, D., Joseph, T., Majeed, M., Rajendran, R., Srinivas, P. S. (1998). Influence of piperine on the pharmacokinetics of curcu- min in animals and human volunteers. Planta Med 64:353-356.
    • (1998) Planta Med , vol.64 , pp. 353-356
    • Shoba, G.1    Joy, D.2    Joseph, T.3    Majeed, M.4    Rajendran, R.5    Srinivas, P.S.6
  • 197
    • 39749084704 scopus 로고    scopus 로고
    • Development of inhibitors of ATP-binding cassette drug transporters: Present status and challenges
    • Shukla, S., Wu, C. P., Ambudkar, S. V. (2008). Development of inhibitors of ATP-binding cassette drug transporters: present status and challenges. Exp Opin Drug Metab Toxicol 4:205-223.
    • (2008) Exp Opin Drug Metab Toxicol , vol.4 , pp. 205-223
    • Shukla, S.1    Wu, C.P.2    Ambudkar, S.V.3
  • 198
    • 58549098231 scopus 로고    scopus 로고
    • Curcumin inhibits the activity of ABCG2/BCRP1, a multi- drug-resistance-linked ABC drug transporter in mice
    • Shukla, S., Zaher, H., Hartz, A., Bauer, B., Ware, J. A., Ambudkar, S. V. (2009). Curcumin inhibits the activity of ABCG2/BCRP1, a multi- drug-resistance-linked ABC drug transporter in mice. Pharm Res 26:480-487.
    • (2009) Pharm Res , vol.26 , pp. 480-487
    • Shukla, S.1    Zaher, H.2    Hartz, A.3    Bauer, B.4    Ware, J.A.5    Ambudkar, S.V.6
  • 199
    • 62449295289 scopus 로고    scopus 로고
    • Introducing nanochemoprevention as a novel approach for cancer control: Proof of principle with green tea polyphenol epigallocatechin-3-gallate
    • Siddiqui, I. A., Adhami, V. M., Bharali, D. J., Hafeez, B. B., Asim, M., Khwaja, S. I., et al. (2009). Introducing nanochemoprevention as a novel approach for cancer control: proof of principle with green tea polyphenol epigallocatechin-3-gallate. Cancer Res 69:1712-1716.
    • (2009) Cancer Res , vol.69 , pp. 1712-1716
    • Siddiqui, I.A.1    Adhami, V.M.2    Bharali, D.J.3    Hafeez, B.B.4    Asim, M.5    Khwaja, S.I.6
  • 201
    • 0042858530 scopus 로고    scopus 로고
    • Induction of multidrug resistance protein 3 in rat liver is associated with altered vectorial excretion of acetaminophen metabolites
    • Slitt, A. L., Cherrington, N. J., Maher, J. M., Klaassen, C. D. (2003). Induction of multidrug resistance protein 3 in rat liver is associated with altered vectorial excretion of acetaminophen metabolites. Drug Metab Dispos 31:1176-1186.
    • (2003) Drug Metab Dispos , vol.31 , pp. 1176-1186
    • Slitt, A.L.1    Cherrington, N.J.2    Maher, J.M.3    Klaassen, C.D.4
  • 202
    • 0036645522 scopus 로고    scopus 로고
    • Dietary curcumin inhibits chemotherapy-induced apoptosis in models of human breast cancer
    • Somasundaram, S., Edmund, N. A., Moore, D. T., Small, G. W, Shi, Y. Y., Orlowski, R. Z. (2002). Dietary curcumin inhibits chemotherapy-induced apoptosis in models of human breast cancer. Cancer Res 62:3868-3875.
    • (2002) Cancer Res , vol.62 , pp. 3868-3875
    • Somasundaram, S.1    Edmund, N.A.2    Moore, D.T.3    Small, G.W.4    Shi, Y.Y.5    Orlowski, R.Z.6
  • 203
    • 0031962002 scopus 로고    scopus 로고
    • P-glycoprotein transporters and the gastrointestinal tract: Evaluation of the potential in vivo relevance of in vitro data employing talinolol as model compound
    • Spahn-Langguth, H., Baktir, G., Radschuweit, A., Okyar, A., Terhaag, B., Ader, P., et al. (1998). P-glycoprotein transporters and the gastrointestinal tract: evaluation of the potential in vivo relevance of in vitro data employing talinolol as model compound. Int J Clin Pharmacol Ther 36:16-24.
    • (1998) Int J Clin Pharmacol Ther , vol.36 , pp. 16-24
    • Spahn-Langguth, H.1    Baktir, G.2    Radschuweit, A.3    Okyar, A.4    Terhaag, B.5    Ader, P.6
  • 204
    • 33749009058 scopus 로고    scopus 로고
    • Expression and transport activity of breast cancer resistance protein (Bcrp/Abcg2) in dually perfused rat placenta and HRP-1 cell line
    • Staud, F., Vackova, Z., Pospechova, K., Pavek, P., Ceckova, M., Libra, A., et al. (2006). Expression and transport activity of breast cancer resistance protein (Bcrp/Abcg2) in dually perfused rat placenta and HRP-1 cell line. J Pharmacol Exp Ther 319:53-62.
    • (2006) J Pharmacol Exp Ther , vol.319 , pp. 53-62
    • Staud, F.1    Vackova, Z.2    Pospechova, K.3    Pavek, P.4    Ceckova, M.5    Libra, A.6
  • 205
    • 0032874193 scopus 로고    scopus 로고
    • Kinetic and biochemical analysis of carrier-mediated efflux of drugs through the blood- brain and blood-cerebrospinal fluid barriers: Importance in the drug delivery to the brain
    • Sugiyama, Y., Kusuhara, H., Suzuki, H. (1999). Kinetic and biochemical analysis of carrier-mediated efflux of drugs through the blood- brain and blood-cerebrospinal fluid barriers: importance in the drug delivery to the brain. J Contr Rel 62:179-186.
    • (1999) J Contr Rel , vol.62 , pp. 179-186
    • Sugiyama, Y.1    Kusuhara, H.2    Suzuki, H.3
  • 206
    • 0142166328 scopus 로고    scopus 로고
    • Cancer chemoprevention with dietary phytochemicals
    • Surh, Y. J. (2003). Cancer chemoprevention with dietary phytochemicals. Nat Rev Cancer 3:768-780.
    • (2003) Nat Rev Cancer , vol.3 , pp. 768-780
    • Surh, Y.J.1
  • 207
    • 4544247421 scopus 로고    scopus 로고
    • Interactions between sulforaphane and apigenin in the induction of UGT1A1 and GSTA1 in Caco-2 cells
    • Svehlikova, V., Wang, S., Jakubikova, J., Williamson, G., Mithen, R., Bao, Y. (2004). Interactions between sulforaphane and apigenin in the induction of UGT1A1 and GSTA1 in Caco-2 cells. Carcinogenesis 25:1629-1637.
    • (2004) Carcinogenesis , vol.25 , pp. 1629-1637
    • Svehlikova, V.1    Wang, S.2    Jakubikova, J.3    Williamson, G.4    Mithen, R.5    Bao, Y.6
  • 209
    • 0025991731 scopus 로고
    • Azidopine noncompetitively interacts with vinblastine and cyclosporin A binding to P-glycoprotein in multidrug-resistant cells
    • Tamai, I., Safa, A. R. (1991). Azidopine noncompetitively interacts with vinblastine and cyclosporin A binding to P-glycoprotein in multidrug-resistant cells. J Bio Chem 266:16796-16800.
    • (1991) J Bio Chem , vol.266 , pp. 16796-16800
    • Tamai, I.1    Safa, A.R.2
  • 210
    • 1942466493 scopus 로고    scopus 로고
    • Bidirectional transport of rhodamine 123 and Hoechst 33342, fluorescence probes of the binding sites on P-glycoprotein, across MDCK- MDR1 cell monolayers
    • Tang, F., Ouyang, H., Yang, J. Z., Borchardt, R. T. (2004). Bidirectional transport of rhodamine 123 and Hoechst 33342, fluorescence probes of the binding sites on P-glycoprotein, across MDCK- MDR1 cell monolayers. J Pharm Sci 93:1185-1194.
    • (2004) J Pharm Sci , vol.93 , pp. 1185-1194
    • Tang, F.1    Ouyang, H.2    Yang, J.Z.3    Borchardt, R.T.4
  • 211
    • 56749164877 scopus 로고    scopus 로고
    • Effects of dietary flavonoids on the transport of cimetidine via P-glycoprotein and cationic transporters in Caco-2 and LLC-PK1 cell models
    • Taur, J. S., Rodriguez-Proteau, R. (2008). Effects of dietary flavonoids on the transport of cimetidine via P-glycoprotein and cationic transporters in Caco-2 and LLC-PK1 cell models. Xenobiotica 38:1536-1550.
    • (2008) Xenobiotica , vol.38 , pp. 1536-1550
    • Taur, J.S.1    Rodriguez-Proteau, R.2
  • 212
    • 33646914643 scopus 로고    scopus 로고
    • Herbal product-drug interactions mediated by induction
    • Tirona, R. G., Bailey, D. G. (2006). Herbal product-drug interactions mediated by induction. Br J Clin Pharmacol 61:677-681.
    • (2006) Br J Clin Pharmacol , vol.61 , pp. 677-681
    • Tirona, R.G.1    Bailey, D.G.2
  • 214
    • 0041402719 scopus 로고    scopus 로고
    • Rhodamine 123 requires carrier-mediated influx for its activity as a P-glycoprotein substrate in Caco-2 cells
    • Troutman, M. D., Thakker, D. R. (2003). Rhodamine 123 requires carrier-mediated influx for its activity as a P-glycoprotein substrate in Caco-2 cells. Pharm Res 20:1192-1199.
    • (2003) Pharm Res , vol.20 , pp. 1192-1199
    • Troutman, M.D.1    Thakker, D.R.2
  • 215
    • 0035196221 scopus 로고    scopus 로고
    • Effect of P-glycoprotein modulators on the pharmacokinetics of camptothecin using microdi- alysis
    • Tsai, T. H., Lee, C. H., Yeh, P. H. (2001). Effect of P-glycoprotein modulators on the pharmacokinetics of camptothecin using microdi- alysis. Br J Pharmacol 134:1245-1252.
    • (2001) Br J Pharmacol , vol.134 , pp. 1245-1252
    • Tsai, T.H.1    Lee, C.H.2    Yeh, P.H.3
  • 216
    • 0036805387 scopus 로고    scopus 로고
    • Effect of organic isothiocy- anates on the P-glycoprotein- and MRP1-mediated transport of daunomycin and vinblastine
    • Tseng, E., Kamath, A., Morris, M. E. (2002). Effect of organic isothiocy- anates on the P-glycoprotein- and MRP1-mediated transport of daunomycin and vinblastine. Pharm Res 19:1509-1515.
    • (2002) Pharm Res , vol.19 , pp. 1509-1515
    • Tseng, E.1    Kamath, A.2    Morris, M.E.3
  • 217
    • 70350537031 scopus 로고    scopus 로고
    • Identification of compounds selectively killing multidrug-resistant cancer cells
    • Turk, D., Hall, M. D., Chu, B. F., Ludwig, J. A., Fales, H. M., Gottesman, M. M., et al. (2009). Identification of compounds selectively killing multidrug-resistant cancer cells. Cancer Res 69:8293-8301.
    • (2009) Cancer Res , vol.69 , pp. 8293-8301
    • Turk, D.1    Hall, M.D.2    Chu, B.F.3    Ludwig, J.A.4    Fales, H.M.5    Gottesman, M.M.6
  • 218
    • 0036186107 scopus 로고    scopus 로고
    • The MRP4/ABCC4 gene encodes a novel apical organic anion transporter in human kidney proximal tubules: Putative efflux pump for urinary cAMP and cGMP
    • van Aubel, R. A., Smeets, P. H., Peters, J. G., Bindels, R. J., Russel, F. G. (2002). The MRP4/ABCC4 gene encodes a novel apical organic anion transporter in human kidney proximal tubules: putative efflux pump for urinary cAMP and cGMP. J Am Soc Nephrol 13:595-603.
    • (2002) J Am Soc Nephrol , vol.13 , pp. 595-603
    • Van Aubel, R.A.1    Smeets, P.H.2    Peters, J.G.3    Bindels, R.J.4    Russel, F.G.5
  • 219
    • 33645977500 scopus 로고    scopus 로고
    • Dendritic cells require multidrug resistance protein 1 (ABCC1) transporter activity for differentiation
    • van de Ven, R., de Jong, M. C., Reurs, A. W., Schoonderwoerd, A. J., Jansen, G., Hooijberg, J. H., et al. (2006). Dendritic cells require multidrug resistance protein 1 (ABCC1) transporter activity for differentiation. J Immunol 176:5191-5198.
    • (2006) J Immunol , vol.176 , pp. 5191-5198
    • Van De Ven, R.1    De Jong, M.C.2    Reurs, A.W.3    Schoonderwoerd, A.J.4    Jansen, G.5    Hooijberg, J.H.6
  • 221
    • 63849152475 scopus 로고    scopus 로고
    • Intestinal breast cancer resistance protein (BCRP)/Bcrp1 and multidrug resistance protein 3 (MRP3)/ Mrp3 are involved in the pharmacokinetics of resveratrol
    • van de Wetering, K., Burkon, A., Feddema, W., Bot, A., de Jonge, H., Somoza, V., et al. (2009). Intestinal breast cancer resistance protein (BCRP)/Bcrp1 and multidrug resistance protein 3 (MRP3)/ Mrp3 are involved in the pharmacokinetics of resveratrol. Mol Pharmacol 75:876-885.
    • (2009) Mol Pharmacol , vol.75 , pp. 876-885
    • Van De Wetering, K.1    Burkon, A.2    Feddema, W.3    Bot, A.4    De Jonge, H.5    Somoza, V.6
  • 222
    • 0029744881 scopus 로고    scopus 로고
    • Multidrug resistance mediated by a bacterial homolog of the human multidrug transporter, MDR1
    • van Veen, H. W., Venema, K., Bolhuis, H., Oussenko, I., Kok, J., Poolman, B., et al. (1996). Multidrug resistance mediated by a bacterial homolog of the human multidrug transporter, MDR1. Proc Natl Acad Sci U S A 93:10668-10672.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 10668-10672
    • Van Veen, H.W.1    Venema, K.2    Bolhuis, H.3    Oussenko, I.4    Kok, J.5    Poolman, B.6
  • 224
    • 0028136603 scopus 로고
    • Competitive inhibition by genistein and ATP dependence of daunorubicin transport in intact MRP- overexpressing human small cell lung cancer cells
    • Versantvoort, C. H., Broxterman, H. J., Lankelma, J., Feller, N., Pinedo, H. M. (1994). Competitive inhibition by genistein and ATP dependence of daunorubicin transport in intact MRP- overexpressing human small cell lung cancer cells. Biochem Pharmacol 48:1129-1136.
    • (1994) Biochem Pharmacol , vol.48 , pp. 1129-1136
    • Versantvoort, C.H.1    Broxterman, H.J.2    Lankelma, J.3    Feller, N.4    Pinedo, H.M.5
  • 225
    • 0030469817 scopus 로고    scopus 로고
    • Acceleration of MRP-associated efflux of rhodamine 123 by genistein and related compounds
    • Versantvoort, C. H., Rhodes, T., Twentyman, P. R. (1996). Acceleration of MRP-associated efflux of rhodamine 123 by genistein and related compounds. Br J Cancer 74:1949-1954.
    • (1996) Br J Cancer , vol.74 , pp. 1949-1954
    • Versantvoort, C.H.1    Rhodes, T.2    Twentyman, P.R.3
  • 226
    • 0027482403 scopus 로고
    • Genistein modulates the decreased drug accumulation in non-P-glycoprotein- mediated multidrug resistant tumour cells
    • Versantvoort, C. H., Schuurhuis, G. J., Pinedo, H. M., Eekman, C. A., Kuiper, C. M., Lankelma, J., et al. (1993). Genistein modulates the decreased drug accumulation in non-P-glycoprotein- mediated multidrug resistant tumour cells. Br J Cancer 68: 939-946.
    • (1993) Br J Cancer , vol.68 , pp. 939-946
    • Versantvoort, C.H.1    Schuurhuis, G.J.2    Pinedo, H.M.3    Eekman, C.A.4    Kuiper, C.M.5    Lankelma, J.6
  • 227
    • 0035290059 scopus 로고    scopus 로고
    • Active secretion and enterocytic drug metabolism barriers to drug absorption
    • DOI 10.1016/S0169-409X(00)00126-5, PII S0169409X00001265
    • Wacher, V. J., Salphati, L., Benet, L. Z. (2001). Active secretion and enterocytic drug metabolism barriers to drug absorption. Adv Drug Deliv Rev 46:89-102. (Pubitemid 33653416)
    • (2000) Advanced Drug Delivery Reviews , vol.46 , Issue.1-3 , pp. 89-102
    • Wacher, V.J.1    Salphati, L.2    Benet, L.Z.3
  • 228
    • 33748040419 scopus 로고    scopus 로고
    • Gomisin A alters substrate interaction and reverses P-glycoprotein- mediated multidrug resistance in HepG2-DR cells
    • Wan, C. K., Zhu, G. Y., Shen, X. L., Chattopadhyay, A., Dey, S., Fong, W. F. (2006). Gomisin A alters substrate interaction and reverses P-glycoprotein-mediated multidrug resistance in HepG2-DR cells. Biochem Pharmacol 72:824-837.
    • (2006) Biochem Pharmacol , vol.72 , pp. 824-837
    • Wan, C.K.1    Zhu, G.Y.2    Shen, X.L.3    Chattopadhyay, A.4    Dey, S.5    Fong, W.F.6
  • 229
    • 0036399061 scopus 로고    scopus 로고
    • Elevation of P-glycoprotein function by a catechin in green tea
    • Wang, E. J., Barecki-Roach, M., Johnson, W. W. (2002). Elevation of P-glycoprotein function by a catechin in green tea. Biochem Biophys Res Commun 297:412-418.
    • (2002) Biochem Biophys Res Commun , vol.297 , pp. 412-418
    • Wang, E.J.1    Barecki-Roach, M.2    Johnson, W.W.3
  • 230
    • 0037391057 scopus 로고    scopus 로고
    • Fluorescent substrates of sister-P-glycoprotein (BSEP) evaluated as markers of active transport and inhibition: Evidence for contingent unequal binding sites
    • Wang, E. J., Casciano, C. N., Clement, R. P., Johnson, W. W. (2003). Fluorescent substrates of sister-P-glycoprotein (BSEP) evaluated as markers of active transport and inhibition: evidence for contingent unequal binding sites. Pharm Res 20:537-544.
    • (2003) Pharm Res , vol.20 , pp. 537-544
    • Wang, E.J.1    Casciano, C.N.2    Clement, R.P.3    Johnson, W.W.4
  • 231
    • 33846464175 scopus 로고    scopus 로고
    • Effects of the flavonoid chrysin on nitrofurantoin pharmacokinetics in rats: Potential involvement of ABCG2
    • Wang, X. D., Morris, M. E. (2007). Effects of the flavonoid chrysin on nitrofurantoin pharmacokinetics in rats: potential involvement of ABCG2. Drug Metab Dispos 35:268-274.
    • (2007) Drug Metab Dispos , vol.35 , pp. 268-274
    • Wang, X.D.1    Morris, M.E.2
  • 232
    • 0347510572 scopus 로고    scopus 로고
    • Lethal quercetin-digoxin interaction in pigs
    • Wang, Y. H., Chao, P. D., Hsiu, S. L., Wen, K. C., Hou, Y. C. (2004). Lethal quercetin-digoxin interaction in pigs. Life Sci 74:1191-1197.
    • (2004) Life Sci , vol.74 , pp. 1191-1197
    • Wang, Y.H.1    Chao, P.D.2    Hsiu, S.L.3    Wen, K.C.4    Hou, Y.C.5
  • 233
    • 0032211902 scopus 로고    scopus 로고
    • Interaction of anti-HIV protease inhibitors with the multidrug transporter P-glycoprotein (P-gp) in human cultured cells
    • Washington, C., Duran, G., Man, M., Sikic, B., Blaschke, T. (1998). Interaction of anti-HIV protease inhibitors with the multidrug transporter P-glycoprotein (P-gp) in human cultured cells. J Acquir Immune Defic Syndr 19:203-209.
    • (1998) J Acquir Immune Defic Syndr , vol.19 , pp. 203-209
    • Washington, C.1    Duran, G.2    Man, M.3    Sikic, B.4    Blaschke, T.5
  • 234
    • 0342762062 scopus 로고    scopus 로고
    • The barrier function of CYP3A4 and P-glycoprotein in the small bowel
    • Watkins, P. B. (1997). The barrier function of CYP3A4 and P-glycoprotein in the small bowel. Adv Drug Deliv Rev 27:161-170.
    • (1997) Adv Drug Deliv Rev , vol.27 , pp. 161-170
    • Watkins, P.B.1
  • 235
    • 0036893815 scopus 로고    scopus 로고
    • Thiopurine metabolism and identification of the thiopurine metabolites transported by MRP4 and MRP5 overexpressed in human embryonic kidney cells
    • Wielinga, P. R., Reid, G., Challa, E. E., van der Heijden, I., van Deemter, L., de Haas, M., et al. (2002). Thiopurine metabolism and identification of the thiopurine metabolites transported by MRP4 and MRP5 overexpressed in human embryonic kidney cells. Mol Pharmacol 62:1321-1331.
    • (2002) Mol Pharmacol , vol.62 , pp. 1321-1331
    • Wielinga, P.R.1    Reid, G.2    Challa, E.E.3    Van Der Heijden, I.4    Van Deemter, L.5    De Haas, M.6
  • 236
    • 12944270590 scopus 로고    scopus 로고
    • Multidrug-resistance protein 5 is a multispecific organic anion transporter able to transport nucleotide analogs
    • Wijnholds, J., Mol, C. A. A. M., van Deemter, L., de Haas, M., Scheffer, G. L., Baas, F., et al. (2000). Multidrug-resistance protein 5 is a multispecific organic anion transporter able to transport nucleotide analogs. Proc Natl Acad Sci U S A 97:7476-7481.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 7476-7481
    • Wijnholds, J.1    Mol, C.A.A.M.2    Van Deemter, L.3    De Haas, M.4    Scheffer, G.L.5    Baas, F.6
  • 237
    • 34547189233 scopus 로고    scopus 로고
    • Interaction of positional isomers of quercetin glucuronides with the transporter ABCC2 (cMOAT, MRP2)
    • Williamson, G., Aeberli, I., Miguet, L., Zhang, Z., Sanchez, M. B., Crespy, V., et al. (2007). Interaction of positional isomers of quercetin glucuronides with the transporter ABCC2 (cMOAT, MRP2). Drug Metab Dispos 35:1262-1268.
    • (2007) Drug Metab Dispos , vol.35 , pp. 1262-1268
    • Williamson, G.1    Aeberli, I.2    Miguet, L.3    Zhang, Z.4    Sanchez, M.B.5    Crespy, V.6
  • 238
    • 25444524567 scopus 로고    scopus 로고
    • Modulatory effects of plant phenols on human multidrug-resistance proteins 1, 4, and 5 (ABCC1, 4, and 5)
    • Wu, C. P., Calcagno, A. M., Hladky, S. B., Ambudkar, S. V., Barrand, M. A. (2005a). Modulatory effects of plant phenols on human multidrug-resistance proteins 1, 4, and 5 (ABCC1, 4, and 5). FEBS J 272:4725-4740.
    • (2005) FEBS J , vol.272 , pp. 4725-4740
    • Wu, C.P.1    Calcagno, A.M.2    Hladky, S.B.3    Ambudkar, S.V.4    Barrand, M.A.5
  • 239
    • 22144455747 scopus 로고    scopus 로고
    • Interactions of mefloquine with ABC proteins, MRP1 (ABCC1), and MRP4 (ABCC4) that are present in human red cell membranes
    • Wu, C. P., Klokouzas, A., Hladky, S. B., Ambudkar, S. V., Barrand, M. A. (2005b). Interactions of mefloquine with ABC proteins, MRP1 (ABCC1), and MRP4 (ABCC4) that are present in human red cell membranes. Biochem Pharmacol 70:500-510.
    • (2005) Biochem Pharmacol , vol.70 , pp. 500-510
    • Wu, C.P.1    Klokouzas, A.2    Hladky, S.B.3    Ambudkar, S.V.4    Barrand, M.A.5
  • 240
    • 45549106377 scopus 로고    scopus 로고
    • Pharmacogenetic characterization of sulfasalazine disposition based on NAT2 and ABCG2 (BCRP) gene polymorphisms in humans
    • Yamasaki, Y., Ieiri, I., Kusuhara, H., Sasaki, T., Kimura, M., Tabuchi, H., et al. (2008). Pharmacogenetic characterization of sulfasalazine disposition based on NAT2 and ABCG2 (BCRP) gene polymorphisms in humans. Clin Pharmacol Ther 84:95-103.
    • (2008) Clin Pharmacol Ther , vol.84 , pp. 95-103
    • Yamasaki, Y.1    Ieiri, I.2    Kusuhara, H.3    Sasaki, T.4    Kimura, M.5    Tabuchi, H.6
  • 242
    • 26444561456 scopus 로고    scopus 로고
    • Modulation of hepatic cytochromes P450 and phase II enzymes by dietary doses of sulforaphane in rats: Implications for its chemopreventive activity
    • Yoxall, V., Kentish, P., Coldham, N., Kuhnert, N., Sauer, M. J., Ioannides, C. (2005). Modulation of hepatic cytochromes P450 and phase II enzymes by dietary doses of sulforaphane in rats: implications for its chemopreventive activity. Int J Cancer 117: 356-362.
    • (2005) Int J Cancer , vol.117 , pp. 356-362
    • Yoxall, V.1    Kentish, P.2    Coldham, N.3    Kuhnert, N.4    Sauer, M.J.5    Ioannides, C.6
  • 243
    • 33644682781 scopus 로고    scopus 로고
    • Breast cancer resistance protein (Bcrp/abcg2) is a major determinant of sulfasalazine absorption and elimination in the mouse
    • Zaher, H., Khan, A. A., Palandra, J., Brayman, T. G., Yu, L., Ware, J. A. (2006). Breast cancer resistance protein (Bcrp/abcg2) is a major determinant of sulfasalazine absorption and elimination in the mouse. Mol Pharm 3:55-61.
    • (2006) Mol Pharm , vol.3 , pp. 55-61
    • Zaher, H.1    Khan, A.A.2    Palandra, J.3    Brayman, T.G.4    Yu, L.5    Ware, J.A.6
  • 244
    • 0037666795 scopus 로고    scopus 로고
    • Evidence for two interacting ligand binding sites in human multidrug resistance protein 2 (ATP binding cassette C2)
    • Zelcer, N., Huisman, M. T., Reid, G., Wielinga, P., Breedveld, P., Kuil, A., et al. (2003a). Evidence for two interacting ligand binding sites in human multidrug resistance protein 2 (ATP binding cassette C2). J Bio Chem 278:23538-23544.
    • (2003) J Bio Chem , vol.278 , pp. 23538-23544
    • Zelcer, N.1    Huisman, M.T.2    Reid, G.3    Wielinga, P.4    Breedveld, P.5    Kuil, A.6
  • 245
    • 0037693882 scopus 로고    scopus 로고
    • Steroid and bile acid conjugates are substrates of human multidrug-resistance protein (MRP) 4 (ATP-binding cassette C4)
    • Zelcer, N., Reid, G., Wielinga, P., Kuil, A., van der Heijden, I., Schuetz, J. D., et al. (2003b). Steroid and bile acid conjugates are substrates of human multidrug-resistance protein (MRP) 4 (ATP-binding cassette C4). Biochem J 371:361-367.
    • (2003) Biochem J , vol.371 , pp. 361-367
    • Zelcer, N.1    Reid, G.2    Wielinga, P.3    Kuil, A.4    Van Der Heijden, I.5    Schuetz, J.D.6
  • 246
    • 0031800792 scopus 로고    scopus 로고
    • Role of organic cation transporters in drug absorption and elimination
    • Zhang, L., Brett, C. M., Giacomini, K. M. (1998). Role of organic cation transporters in drug absorption and elimination. Annu Rev Pharmacol Toxicol 38:431-460.
    • (1998) Annu Rev Pharmacol Toxicol , vol.38 , pp. 431-460
    • Zhang, L.1    Brett, C.M.2    Giacomini, K.M.3
  • 247
    • 34249297623 scopus 로고    scopus 로고
    • Mechanistic study on the intestinal absorption and disposition of baicalein
    • Zhang, L., Lin, G., Kovacs, B., Jani, M., Krajcsi, P., Zuo, Z. (2007a). Mechanistic study on the intestinal absorption and disposition of baicalein. Eur J Pharm Sci 31:221-231.
    • (2007) Eur J Pharm Sci , vol.31 , pp. 221-231
    • Zhang, L.1    Lin, G.2    Kovacs, B.3    Jani, M.4    Krajcsi, P.5    Zuo, Z.6
  • 248
    • 8444230840 scopus 로고    scopus 로고
    • Investigation of intestinal absorption and disposition of green-tea catechins by Caco-2 monolayer model
    • Zhang, L., Zheng, Y., Chow, M. S. S., Zuo, Z. (2004a). Investigation of intestinal absorption and disposition of green-tea catechins by Caco-2 monolayer model. Int J Pharm 287:1-12.
    • (2004) Int J Pharm , vol.287 , pp. 1-12
    • Zhang, L.1    Zheng, Y.2    Chow, M.S.S.3    Zuo, Z.4
  • 249
    • 37549066909 scopus 로고    scopus 로고
    • Intestinal and hepatic glucuronida- tion of flavonoids
    • Zhang, L., Zuo, Z., Lin, G. (2007b). Intestinal and hepatic glucuronida- tion of flavonoids. Mol Pharm 4:833-845.
    • (2007) Mol Pharm , vol.4 , pp. 833-845
    • Zhang, L.1    Zuo, Z.2    Lin, G.3
  • 250
    • 2442536000 scopus 로고    scopus 로고
    • In vivo reversal of doxorubicin resistance by (-)-epigallocatechin gallate in a solid human carcinoma xenograft
    • Zhang, Q., Wei, D., Liu, J. (2004b). In vivo reversal of doxorubicin resistance by (-)-epigallocatechin gallate in a solid human carcinoma xenograft. Cancer Lett 208:179-186.
    • (2004) Cancer Lett , vol.208 , pp. 179-186
    • Zhang, Q.1    Wei, D.2    Liu, J.3
  • 251
    • 0043127383 scopus 로고    scopus 로고
    • Effect of the flavonoids, biochanin A and silymarin, on the P-glycoprotein-mediated transport of dig- oxin and vinblastine in human intestinal Caco-2 cells
    • Zhang, S., Morris, M. E. (2003a). Effect of the flavonoids, biochanin A and silymarin, on the P-glycoprotein-mediated transport of dig- oxin and vinblastine in human intestinal Caco-2 cells. Pharm Res 20:1184-1191.
    • (2003) Pharm Res , vol.20 , pp. 1184-1191
    • Zhang, S.1    Morris, M.E.2
  • 252
    • 0037371275 scopus 로고    scopus 로고
    • Effects of the flavonoids, biochanin A, morin, phloretin, and silymarin, on P-glycoprotein-mediated transport
    • Zhang, S., Morris, M. E. (2003b). Effects of the flavonoids, biochanin A, morin, phloretin, and silymarin, on P-glycoprotein-mediated transport. J Pharmacol Exp Ther 304:1258-1267.
    • (2003) J Pharmacol Exp Ther , vol.304 , pp. 1258-1267
    • Zhang, S.1    Morris, M.E.2
  • 253
    • 2142711101 scopus 로고    scopus 로고
    • Flavonoids are inhibitors of breast cancer resistance protein (ABCG2)-mediated transport
    • Zhang, S. Z., Yang, X. N., Morris, M. E. (2004c). Flavonoids are inhibitors of breast cancer resistance protein (ABCG2)-mediated transport. Mol Pharmacol 65:1208-1216.
    • (2004) Mol Pharmacol , vol.65 , pp. 1208-1216
    • Zhang, S.Z.1    Yang, X.N.2    Morris, M.E.3
  • 255
    • 46449099725 scopus 로고    scopus 로고
    • Effects of spice constituents on P-glycoprotein-mediated transport and CYP3A4-mediated metabolism in vitro
    • Zhang, W., Lim, L. Y. (2008). Effects of spice constituents on P-glycoprotein-mediated transport and CYP3A4-mediated metabolism in vitro. Drug Metab Dispos 36:1283-1290.
    • (2008) Drug Metab Dispos , vol.36 , pp. 1283-1290
    • Zhang, W.1    Lim, L.Y.2
  • 256
    • 33845937786 scopus 로고    scopus 로고
    • Impact of curcumin-induced changes in P-glycoprotein and CYP3A expression on the pharmacokinetics of peroral celiprolol and midazolam in rats
    • Zhang, W., Tan, T. M., Lim, L. Y. (2007c). Impact of curcumin-induced changes in P-glycoprotein and CYP3A expression on the pharmacokinetics of peroral celiprolol and midazolam in rats. Drug Metab Dispos 35:110-115.
    • (2007) Drug Metab Dispos , vol.35 , pp. 110-115
    • Zhang, W.1    Tan, T.M.2
  • 257
    • 0026577605 scopus 로고
    • A major inducer of anticarcinogenic protective enzymes from broccoli: Isolation and elucidation of structure
    • Zhang, Y., Talalay, P., Cho, C. G., Posner, G. H. (1992). A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure. Proc Natl Acad Sci U S A 89:2399-2403.
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 2399-2403
    • Zhang, Y.1    Talalay, P.2    Cho, C.G.3    Posner, G.H.4
  • 258
    • 0035054725 scopus 로고    scopus 로고
    • The gut as a barrier to drug absorption-combined role of cytochrome P450 3A and P-glycoprotein
    • Zhang, Y. C., Benet, L. Z. (2001). The gut as a barrier to drug absorption-combined role of cytochrome P450 3A and P-glycoprotein. Clin Pharmacokinet 40:159-168.
    • (2001) Clin Pharmacokinet , vol.40 , pp. 159-168
    • Zhang, Y.C.1    Benet, L.Z.2
  • 259
    • 40849097788 scopus 로고    scopus 로고
    • The breast cancer resistance protein (Bcrp1/ Abcg2) limits fetal distribution of glyburide in the pregnant mouse: An Obstetric-Fetal Pharmacology Research Unit Network and University of Washington Specialized Center of Research Study
    • Zhou, L., Naraharisetti, S. B., Wang, H., Unadkat, J. D., Hebert, M. F., Mao, Q. (2008a). The breast cancer resistance protein (Bcrp1/ Abcg2) limits fetal distribution of glyburide in the pregnant mouse: an Obstetric-Fetal Pharmacology Research Unit Network and University of Washington Specialized Center of Research Study. Mol Pharmacol 73:949-959.
    • (2008) Mol Pharmacol , vol.73 , pp. 949-959
    • Zhou, L.1    Naraharisetti, S.B.2    Wang, H.3    Unadkat, J.D.4    Hebert, M.F.5    Mao, Q.6
  • 260
    • 1642360726 scopus 로고    scopus 로고
    • Herbal modulation of P-glycoprotein
    • Zhou, S., Lim, L. Y., Chowbay, B. (2004). Herbal modulation of P-glycoprotein. Drug Metab Rev 36:57-104.
    • (2004) Drug Metab Rev , vol.36 , pp. 57-104
    • Zhou, S.1    Lim, L.Y.2    Chowbay, B.3
  • 261
    • 53349117254 scopus 로고    scopus 로고
    • Substrates and inhibitors of human multidrug-resist- ance-associated proteins and the implications in drug development
    • Zhou, S. F., Wang, L. L., Di, Y. M., Xue, C. C., Duan, W., Li, C. G., et al. (2008b). Substrates and inhibitors of human multidrug-resist- ance-associated proteins and the implications in drug development. Curr Med Chem 15:1981-2039.
    • (2008) Curr Med Chem , vol.15 , pp. 1981-2039
    • Zhou, S.F.1    Wang, L.L.2    Di, Y.M.3    Xue, C.C.4    Duan, W.5    Li, C.G.6
  • 262
    • 21344445915 scopus 로고    scopus 로고
    • In vitro and in vivo characterizations of tetrandrine on the reversal of P-glycoprotein-mediated drug resistance to paclitaxel
    • Zhu, X., Sui, M., Fan, W. (2005). In vitro and in vivo characterizations of tetrandrine on the reversal of P-glycoprotein-mediated drug resistance to paclitaxel. Anticancer Res 25:1953-1962.
    • (2005) Anticancer Res , vol.25 , pp. 1953-1962
    • Zhu, X.1    Sui, M.2    Fan, W.3


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